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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs188135659
log Bayes Factor = 15.5868
Chromosome 3   position 19,839,062  (GRCh37) Explore rs188135659 on Ensembl!
Variant rs188135659 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
J34 Other disorders of nose and nasal sinuses
0.991 0.009 0.000
J30-J39 Other diseases of upper respiratory tract
0.991 0.009 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.990 0.010 0.000
I25.2 Old myocardial infarction
0.988 0.012 0.000
Chapter VII Diseases of the eye and adnexa
0.985 0.015 0.000
J34.2 Deviated nasal septum
0.982 0.018 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.982 0.018 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.980 0.020 0.000
I44 Atrioventricular and left bundle-branch block
0.979 0.021 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.975 0.025 0.000
E10-E14 Diabetes mellitus
0.973 0.027 0.000
J34.3 Hypertrophy of nasal turbinates
0.971 0.029 0.000
H65-H75 Diseases of middle ear and mastoid
0.970 0.030 0.000
E11 Non-insulin-dependent diabetes mellitus
0.968 0.032 0.000
I44.7 Left bundle-branch block, unspecified
0.964 0.036 0.000
E11.9 Without complications
0.960 0.040 0.000
Chapter I Certain infectious and parasitic diseases
0.956 0.044 0.000
I05-I09 Chronic rheumatic heart diseases
0.951 0.049 0.000
M45-M49 Spondylopathies
0.950 0.050 0.000
I60-I69 Cerebrovascular diseases
0.950 0.050 0.000
S60-S69 Injuries to the wrist and hand
0.945 0.055 0.000
H72 Perforation of tympanic membrane
0.940 0.060 0.000
I51 Complications and ill-defined descriptions of heart disease
0.932 0.068 0.000
D50-D53 Nutritional anaemias
0.928 0.072 0.000
T39.1 4-Aminophenol derivatives
0.919 0.081 0.000
I08 Multiple valve diseases
0.917 0.083 0.000
I20 Angina pectoris
0.915 0.085 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.910 0.090 0.000
I49 Other cardiac arrhythmias
0.910 0.090 0.000
M48 Other spondylopathies
0.910 0.090 0.000
Chapter II Neoplasms
0.908 0.092 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.908 0.092 0.000
A00-A09 Intestinal infectious diseases
0.904 0.096 0.000
M20-M25 Other joint disorders
0.901 0.099 0.000
I45 Other conduction disorders
0.897 0.103 0.000
D50 Iron deficiency anaemia
0.893 0.107 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.887 0.113 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.887 0.113 0.000
I51.8 Other ill-defined heart diseases
0.886 0.114 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.885 0.115 0.000
S61 Open wound of wrist and hand
0.882 0.118 0.000
I08.0 Disorders of both mitral and aortic valves
0.882 0.118 0.000
I67 Other cerebrovascular diseases
0.881 0.119 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.881 0.119 0.000
M48.0 Spinal stenosis
0.880 0.120 0.000
M50-M54 Other dorsopathies
0.880 0.120 0.000
H66 Suppurative and unspecified otitis media
0.879 0.121 0.000
I44.0 Atrioventricular block, first degree
0.879 0.121 0.000
D50.9 Iron deficiency anaemia, unspecified
0.877 0.123 0.000
S00-S09 Injuries to the head
0.865 0.135 0.000
H53-H54 Visual disturbances and blindness
0.865 0.135 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.864 0.136 0.000
H50 Other strabismus
0.854 0.146 0.000
I24 Other acute ischaemic heart diseases
0.853 0.147 0.000
S80-S89 Injuries to the knee and lower leg
0.852 0.148 0.000
M25 Other joint disorders, not elsewhere classified
0.852 0.148 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.848 0.152 0.000
I47 Paroxysmal tachycardia
0.848 0.152 0.000
S90-S99 Injuries to the ankle and foot
0.846 0.154 0.000
H40-H42 Glaucoma
0.843 0.157 0.000
H30-H36 Disorders of choroid and retina
0.843 0.157 0.000
E20-E35 Disorders of other endocrine glands
0.838 0.162 0.000
I21 Acute myocardial infarction
0.831 0.169 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.831 0.169 0.000
M48.02 Spinal stenosis (Cervical region)
0.830 0.170 0.000
C15-C26 Malignant neoplasms of digestive organs
0.828 0.172 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.827 0.173 0.000
I42 Cardiomyopathy
0.827 0.173 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.825 0.175 0.000
M80-M85 Disorders of bone density and structure
0.824 0.176 0.000
I35 Nonrheumatic aortic valve disorders
0.816 0.184 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.815 0.185 0.000
H66.3 Other chronic suppurative otitis media
0.815 0.185 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
S61.0 Open wound of finger(s) without damage to nail
0.813 0.187 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.809 0.191 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.805 0.195 0.000
T40.2 Other opioids
0.805 0.195 0.000
M22 Disorders of patella
0.804 0.196 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.804 0.196 0.000
M25.7 Osteophyte
0.803 0.197 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.802 0.198 0.000
M46 Other inflammatory spondylopathies
0.800 0.200 0.000
T39.0 Salicylates
0.798 0.202 0.000
I20.8 Other forms of angina pectoris
0.795 0.205 0.000
S70-S79 Injuries to the hip and thigh
0.795 0.205 0.000
H72.0 Central perforation of tympanic membrane
0.794 0.206 0.000
M54 Dorsalgia
0.790 0.210 0.000
I47.1 Supraventricular tachycardia
0.788 0.212 0.000
I51.9 Heart disease, unspecified
0.786 0.214 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.786 0.214 0.000
E11.2 With renal complications
0.785 0.215 0.000
I46 Cardiac arrest
0.785 0.215 0.000
I49.5 Sick sinus syndrome
0.785 0.215 0.000
I20.0 Unstable angina
0.783 0.217 0.000
Chapter V Mental and behavioural disorders
0.783 0.217 0.000
I25.5 Ischaemic cardiomyopathy
0.781 0.219 0.000
E10 Insulin-dependent diabetes mellitus
0.781 0.219 0.000
H90-H95 Other disorders of ear
0.781 0.219 0.000
D60-D64 Aplastic and other anaemias
0.780 0.220 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.780 0.220 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.776 0.224 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.775 0.225 0.000
C18 Malignant neoplasm of colon
0.772 0.228 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.772 0.228 0.000
I69 Sequelae of cerebrovascular disease
0.770 0.230 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.770 0.230 0.000
H18 Other disorders of cornea
0.769 0.231 0.000
H53 Visual disturbances
0.769 0.231 0.000
I95 Hypotension
0.767 0.233 0.000
H72.8 Other perforations of tympanic membrane
0.767 0.233 0.000
Chapter XX External causes of morbidity and mortality
0.759 0.241 0.000
I67.9 Cerebrovascular disease, unspecified
0.759 0.241 0.000
I67.2 Cerebral atherosclerosis
0.757 0.243 0.000
M48.09 Spinal stenosis (Site unspecified)
0.754 0.245 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
I49.1 Atrial premature depolarisation
0.753 0.247 0.000
A30-A49 Other bacterial diseases
0.752 0.248 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.752 0.248 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.750 0.250 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.750 0.250 0.000
C60-C63 Malignant neoplasms of male genital organs
0.749 0.251 0.000
M25.78 Osteophyte (Other)
0.749 0.251 0.000
S40-S49 Injuries to the shoulder and upper arm
0.749 0.251 0.000
M40-M43 Deforming dorsopathies
0.745 0.255 0.000
I45.1 Other and unspecified right bundle-branch block
0.745 0.255 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.745 0.255 0.000
D80-D89 Certain disorders involving the immune mechanism
0.744 0.256 0.000
H40 Glaucoma
0.742 0.258 0.000
J90-J94 Other diseases of pleura
0.741 0.259 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.741 0.259 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.741 0.259 0.000
H50.9 Strabismus, unspecified
0.740 0.260 0.000
H35 Other retinal disorders
0.738 0.262 0.000
H55-H59 Other disorders of eye and adnexa
0.736 0.263 0.000
H65 Nonsuppurative otitis media
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.735 0.265 0.000
I63 Cerebral infarction
0.735 0.265 0.000
J36 Peritonsillar abscess
0.735 0.265 0.000
S61.1 Open wound of finger(s) with damage to nail
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.733 0.267 0.000
I45.5 Other specified heart block
0.733 0.267 0.000
S02 Fracture of skull and facial bones
0.732 0.268 0.000
E27 Other disorders of adrenal gland
0.731 0.269 0.000
S06 Intracranial injury
0.729 0.271 0.000
E11.3 With ophthalmic complications
0.728 0.272 0.000
E11.4 With neurological complications
0.726 0.274 0.000
H17 Corneal scars and opacities
0.725 0.275 0.000
J32 Chronic sinusitis
0.724 0.276 0.000
J35 Chronic diseases of tonsils and adenoids
0.724 0.276 0.000
H50.1 Divergent concomitant strabismus
0.723 0.277 0.000
E13 Other specified diabetes mellitus
0.723 0.277 0.000
H10-H13 Disorders of conjunctiva
0.721 0.279 0.000
S69 Other and unspecified injuries of wrist and hand
0.718 0.282 0.000
H71 Cholesteatoma of middle ear
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
M22.2 Patellofemoral disorders
0.716 0.284 0.000
M54.3 Sciatica
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.285 0.000
T36 Poisoning by systemic antibiotics
0.714 0.285 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.711 0.289 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.711 0.289 0.000
I50 Heart failure
0.711 0.289 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.711 0.289 0.000
J37 Chronic laryngitis and laryngotracheitis
0.710 0.289 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.710 0.290 0.000
M35 Other systemic involvement of connective tissue
0.710 0.290 0.000
L40-L45 Papulosquamous disorders
0.709 0.291 0.000
I24.8 Other forms of acute ischaemic heart disease
0.708 0.291 0.000
S92 Fracture of foot, except ankle
0.707 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
I45.6 Preexcitation syndrome
0.707 0.293 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.706 0.294 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.706 0.294 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.706 0.294 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.706 0.294 0.000
S63.6 Sprain and strain of finger(s)
0.705 0.295 0.000
I67.1 Cerebral aneurysm, nonruptured
0.705 0.295 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
M60-M63 Disorders of muscles
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.704 0.296 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.704 0.296 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.703 0.296 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.703 0.296 0.000
T39.4 Antirheumatics, not elsewhere classified
0.703 0.296 0.000
T39.2 Pyrazolone derivatives
0.703 0.296 0.000
I33 Acute and subacute endocarditis
0.703 0.297 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.703 0.297 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.703 0.297 0.000
E40-E46 Malnutrition
0.703 0.297 0.000
J60-J70 Lung diseases due to external agents
0.702 0.298 0.000
D00-D09 In situ neoplasms
0.702 0.298 0.000
I44.6 Other and unspecified fascicular block
0.702 0.298 0.000
I44.5 Left posterior fascicular block
0.702 0.298 0.000
I44.4 Left anterior fascicular block
0.702 0.298 0.000
I44.3 Other and unspecified atrioventricular block
0.702 0.298 0.000
B95-B98 Bacterial, viral and other infectious agents
0.701 0.299 0.000
I95.9 Hypotension, unspecified
0.700 0.300 0.000
I49.9 Cardiac arrhythmia, unspecified
0.700 0.300 0.000
D55-D59 Haemolytic anaemias
0.699 0.301 0.000
C18.4 Transverse colon
0.699 0.301 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
E12 Malnutrition-related diabetes mellitus
0.698 0.302 0.000
I49.8 Other specified cardiac arrhythmias
0.698 0.302 0.000
H50.0 Convergent concomitant strabismus
0.697 0.303 0.000
I60 Subarachnoid haemorrhage
0.696 0.303 0.000
M54.9 Dorsalgia, unspecified
0.696 0.304 0.000
A08 Viral and other specified intestinal infections
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.695 0.305 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.695 0.305 0.000
H74 Other disorders of middle ear and mastoid
0.695 0.305 0.000
H70 Mastoiditis and related conditions
0.695 0.305 0.000
H69 Other disorders of Eustachian tube
0.695 0.305 0.000
H68 Eustachian salpingitis and obstruction
0.695 0.305 0.000
H67 Otitis media in diseases classified elsewhere
0.695 0.305 0.000
S67 Crushing injury of wrist and hand
0.695 0.305 0.000
J40-J47 Chronic lower respiratory diseases
0.694 0.306 0.000
L60-L75 Disorders of skin appendages
0.694 0.306 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.694 0.306 0.000
E11.8 With unspecified complications
0.694 0.306 0.000
E11.7 With multiple complications
0.694 0.306 0.000
E11.6 With other specified complications
0.694 0.306 0.000
E11.5 With peripheral circulatory complications
0.694 0.306 0.000
E11.1 With ketoacidosis
0.694 0.306 0.000
E11.0 With coma
0.694 0.306 0.000
M25.5 Pain in joint
0.693 0.307 0.000
S89 Other and unspecified injuries of lower leg
0.692 0.307 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.692 0.308 0.000
B35-B49 Mycoses
0.692 0.308 0.000
I31 Other diseases of pericardium
0.691 0.309 0.000
A04 Other bacterial intestinal infections
0.691 0.309 0.000
M53 Other dorsopathies, not elsewhere classified
0.690 0.310 0.000
D75 Other diseases of blood and blood-forming organs
0.689 0.311 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.686 0.314 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.686 0.314 0.000
B99-B99 Other infectious diseases
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.315 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
B50-B64 Protozoal diseases
0.685 0.315 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.685 0.315 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.315 0.000
A75-A79 Rickettsioses
0.685 0.315 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.315 0.000
A65-A69 Other spirochaetal diseases
0.685 0.315 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.315 0.000
A15-A19 Tuberculosis
0.685 0.315 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.315 0.000
H60-H62 Diseases of external ear
0.684 0.316 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.683 0.317 0.000
I09 Other rheumatic heart diseases
0.682 0.318 0.000
I06 Rheumatic aortic valve diseases
0.682 0.318 0.000
I05 Rheumatic mitral valve diseases
0.682 0.318 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.682 0.318 0.000
M47 Spondylosis
0.682 0.318 0.000
D64 Other anaemias
0.682 0.318 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.682 0.318 0.000
M49 Spondylopathies in diseases classified elsewhere
0.681 0.319 0.000
M45 Ankylosing spondylitis
0.681 0.319 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.681 0.319 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.681 0.319 0.000
I62 Other nontraumatic intracranial haemorrhage
0.681 0.319 0.000
D51 Vitamin B12 deficiency anaemia
0.681 0.319 0.000
I07 Rheumatic tricuspid valve diseases
0.681 0.319 0.000
H40.9 Glaucoma, unspecified
0.680 0.320 0.000
C50-C50 Malignant neoplasm of breast
0.680 0.320 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.679 0.321 0.000
S65 Injury of blood vessels at wrist and hand level
0.678 0.322 0.000
S60 Superficial injury of wrist and hand
0.678 0.322 0.000
J20-J22 Other acute lower respiratory infections
0.675 0.325 0.000
H90 Conductive and sensorineural hearing loss
0.675 0.325 0.000
I21.4 Acute subendocardial myocardial infarction
0.674 0.326 0.000
H72.2 Other marginal perforations of tympanic membrane
0.674 0.326 0.000
H72.1 Attic perforation of tympanic membrane
0.674 0.326 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.672 0.327 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.669 0.331 0.000
I51.6 Cardiovascular disease, unspecified
0.668 0.331 0.000
I51.5 Myocardial degeneration
0.668 0.331 0.000
I51.4 Myocarditis, unspecified
0.668 0.331 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.668 0.331 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.668 0.331 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.668 0.331 0.000
I51.0 Cardiac septal defect, acquired
0.668 0.331 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.668 0.332 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.667 0.333 0.000
J31.0 Chronic rhinitis
0.667 0.333 0.000
D53 Other nutritional anaemias
0.665 0.334 0.000
D52 Folate deficiency anaemia
0.665 0.334 0.000
I46.9 Cardiac arrest, unspecified
0.665 0.335 0.000
H52 Disorders of refraction and accommodation
0.664 0.336 0.000
B25-B34 Other viral diseases
0.664 0.336 0.000
S61.8 Open wound of other parts of wrist and hand
0.664 0.336 0.000
D70 Agranulocytosis
0.663 0.337 0.000
J09-J18 Influenza and pneumonia
0.663 0.337 0.000
I42.0 Dilated cardiomyopathy
0.662 0.338 0.000
M54.39 Sciatica (Site unspecified)
0.661 0.339 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.659 0.341 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.659 0.341 0.000
I08.9 Multiple valve disease, unspecified
0.657 0.343 0.000
I08.8 Other multiple valve diseases
0.657 0.343 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.657 0.343 0.000
I20.9 Angina pectoris, unspecified
0.657 0.343 0.000
S64 Injury of nerves at wrist and hand level
0.657 0.343 0.000
C18.9 Colon, unspecified
0.657 0.343 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.656 0.343 0.000
H43-H45 Disorders of vitreous body and globe
0.656 0.344 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.656 0.344 0.000
S91 Open wound of ankle and foot
0.656 0.344 0.000
I20.1 Angina pectoris with documented spasm
0.656 0.344 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.655 0.345 0.000
I42.2 Other hypertrophic cardiomyopathy
0.655 0.345 0.000
M81 Osteoporosis without pathological fracture
0.654 0.346 0.000
H20 Iridocyclitis
0.653 0.347 0.000
H51 Other disorders of binocular movement
0.652 0.347 0.000
H49 Paralytic strabismus
0.652 0.347 0.000
I49.2 Junctional premature depolarisation
0.652 0.348 0.000
M48.9 Spondylopathy, unspecified
0.652 0.348 0.000
M48.8 Other specified spondylopathies
0.652 0.348 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.652 0.348 0.000
M48.4 Fatigue fracture of vertebra
0.652 0.348 0.000
M48.3 Traumatic spondylopathy
0.652 0.348 0.000
M48.2 Kissing spine
0.652 0.348 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.652 0.348 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.651 0.349 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.651 0.349 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.651 0.349 0.000
S50-S59 Injuries to the elbow and forearm
0.651 0.349 0.000
S81 Open wound of lower leg
0.649 0.351 0.000
M48.06 Spinal stenosis (Lumbar region)
0.648 0.352 0.000
A07 Other protozoal intestinal diseases
0.648 0.352 0.000
A06 Amoebiasis
0.648 0.352 0.000
A05 Other bacterial foodborne intoxications
0.648 0.352 0.000
A03 Shigellosis
0.648 0.352 0.000
A02 Other Salmonella infections
0.648 0.352 0.000
A01 Typhoid and paratyphoid fevers
0.648 0.352 0.000
A00 Cholera
0.648 0.352 0.000
H36 Retinal disorders in diseases classified elsewhere
0.648 0.352 0.000
H73 Other disorders of tympanic membrane
0.647 0.353 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.646 0.354 0.000
M34 Systemic sclerosis
0.646 0.354 0.000
M33 Dermatopolymyositis
0.646 0.354 0.000
M32 Systemic lupus erythematosus
0.646 0.354 0.000
M30 Polyarteritis nodosa and related conditions
0.646 0.354 0.000
M80 Osteoporosis with pathological fracture
0.646 0.354 0.000
H18.9 Disorder of cornea, unspecified
0.645 0.355 0.000
T90 Sequelae of injuries of head
0.645 0.355 0.000
I71 Aortic aneurysm and dissection
0.644 0.356 0.000
I10-I15 Hypertensive diseases
0.644 0.356 0.000
I45.9 Conduction disorder, unspecified
0.643 0.357 0.000
I45.8 Other specified conduction disorders
0.643 0.357 0.000
I45.4 Nonspecific intraventricular block
0.643 0.357 0.000
I45.3 Trifascicular block
0.643 0.357 0.000
I45.2 Bifascicular block
0.643 0.357 0.000
I45.0 Right fascicular block
0.643 0.357 0.000
H54 Blindness and low vision
0.643 0.357 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.643 0.357 0.000
M24 Other specific joint derangements
0.641 0.359 0.000
X60-X84 Intentional self-harm
0.641 0.359 0.000
M31 Other necrotising vasculopathies
0.641 0.359 0.000
D50.1 Sideropenic dysphagia
0.640 0.360 0.000
M22.4 Chondromalacia patellae
0.639 0.361 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.639 0.361 0.000
I22 Subsequent myocardial infarction
0.638 0.362 0.000
S68 Traumatic amputation of wrist and hand
0.637 0.363 0.000
I61 Intracerebral haemorrhage
0.636 0.364 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.636 0.364 0.000
H21 Other disorders of iris and ciliary body
0.636 0.364 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.636 0.364 0.000
H16 Keratitis
0.636 0.364 0.000
H15 Disorders of sclera
0.636 0.364 0.000
I49.0 Ventricular fibrillation and flutter
0.636 0.364 0.000
C61 Malignant neoplasm of prostate
0.635 0.365 0.000
H53.2 Diplopia
0.635 0.365 0.000
J39 Other diseases of upper respiratory tract
0.634 0.365 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.634 0.366 0.000
T40.8 Lysergide [LSD]
0.634 0.366 0.000
T40.7 Cannabis (derivatives)
0.634 0.366 0.000
T40.6 Other and unspecified narcotics
0.634 0.366 0.000
T40.5 Cocaine
0.634 0.366 0.000
T40.4 Other synthetic narcotics
0.634 0.366 0.000
T40.3 Methadone
0.634 0.366 0.000
T40.1 Heroin
0.634 0.366 0.000
T40.0 Opium
0.634 0.366 0.000
C20 Malignant neoplasm of rectum
0.634 0.366 0.000
J44 Other chronic obstructive pulmonary disease
0.633 0.367 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.633 0.367 0.000
S61.7 Multiple open wounds of wrist and hand
0.632 0.367 0.000
J90 Pleural effusion, not elsewhere classified
0.632 0.368 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.632 0.368 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.632 0.368 0.000
I67.5 Moyamoya disease
0.632 0.368 0.000
I67.4 Hypertensive encephalopathy
0.632 0.368 0.000
I67.3 Progressive vascular leukoencephalopathy
0.632 0.368 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.632 0.368 0.000
S62 Fracture at wrist and hand level
0.631 0.368 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.631 0.369 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.631 0.369 0.000
M48.04 Spinal stenosis (Thoracic region)
0.631 0.369 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.631 0.369 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.631 0.369 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.631 0.369 0.000
I49.3 Ventricular premature depolarisation
0.631 0.369 0.000
E10.1 With ketoacidosis
0.631 0.369 0.000
M25.76 Osteophyte (Lower leg)
0.631 0.369 0.000
H66.9 Otitis media, unspecified
0.631 0.369 0.000
H66.4 Suppurative otitis media, unspecified
0.631 0.369 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.631 0.369 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.631 0.369 0.000
H66.0 Acute suppurative otitis media
0.631 0.369 0.000
L40 Psoriasis
0.630 0.370 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.630 0.370 0.000
I35.9 Aortic valve disorder, unspecified
0.630 0.370 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.629 0.371 0.000
E65-E68 Obesity and other hyperalimentation
0.629 0.371 0.000
D45 Polycythaemia vera
0.628 0.372 0.000
S71 Open wound of hip and thigh
0.628 0.372 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.627 0.373 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.626 0.374 0.000
H40.0 Glaucoma suspect
0.626 0.374 0.000
I49.4 Other and unspecified premature depolarisation
0.626 0.374 0.000
T91 Sequelae of injuries of neck and trunk
0.626 0.374 0.000
M84 Disorders of continuity of bone
0.625 0.375 0.000
H53.0 Amblyopia ex anopsia
0.625 0.375 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.625 0.375 0.000
S92.3 Fracture of metatarsal bone
0.625 0.375 0.000
H35.8 Other specified retinal disorders
0.624 0.376 0.000
T45.0 Antiallergic and antiemetic drugs
0.624 0.376 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.624 0.376 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.623 0.377 0.000
M51 Other intervertebral disk disorders
0.622 0.377 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.623 0.377 0.000
H18.6 Keratoconus
0.622 0.378 0.000
A41 Other septicaemia
0.622 0.378 0.000
M50 Cervical disk disorders
0.621 0.378 0.000
M35.3 Polymyalgia rheumatica
0.621 0.379 0.000
S01 Open wound of head
0.621 0.379 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.621 0.379 0.000
D72 Other disorders of white blood cells
0.620 0.380 0.000
S08 Traumatic amputation of part of head
0.620 0.380 0.000
S07 Crushing injury of head
0.620 0.380 0.000
S05 Injury of eye and orbit
0.620 0.380 0.000
S04 Injury of cranial nerves
0.620 0.380 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.620 0.380 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.620 0.380 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.620 0.380 0.000
I99 Other and unspecified disorders of circulatory system
0.620 0.380 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.618 0.382 0.000
S80 Superficial injury of lower leg
0.618 0.382 0.000
I77 Other disorders of arteries and arterioles
0.617 0.383 0.000
E22 Hyperfunction of pituitary gland
0.616 0.384 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.615 0.384 0.000
H34 Retinal vascular occlusions
0.615 0.385 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.615 0.385 0.000
M21.1 Varus deformity, not elsewhere classified
0.613 0.386 0.000
H80-H83 Diseases of inner ear
0.613 0.387 0.000
S82 Fracture of lower leg, including ankle
0.613 0.387 0.000
H50.8 Other specified strabismus
0.612 0.387 0.000
H50.6 Mechanical strabismus
0.612 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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