TreeWAS – Variant ID: rs188845491

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.085	0.915
Chapter XXI Factors influencing health status and contact with health services	0.085	0.915
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.083	0.917
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.077	0.923
Z86 Personal history of certain other diseases	0.074	0.926
Z95 Presence of cardiac and vascular implants and grafts	0.071	0.929
Chapter XIV Diseases of the genitourinary system	0.068	0.931
Chapter XI Diseases of the digestive system	0.068	0.931
Chapter X Diseases of the respiratory system	0.068	0.932
Z87 Personal history of other diseases and conditions	0.067	0.933
Chapter IV Endocrine, nutritional and metabolic diseases	0.066	0.934
Z70-Z76 Persons encountering health services in other circumstances	0.066	0.934
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.065	0.934
Z86.4 Personal history of psychoactive substance abuse	0.065	0.935
R50-R69 General symptoms and signs	0.065	0.935
Z00-Z13 Persons encountering health services for examination and investigation	0.065	0.935
Chapter IX Diseases of the circulatory system	0.064	0.936
Chapter II Neoplasms	0.064	0.936
Z90 Acquired absence of organs, not elsewhere classified	0.064	0.936
Chapter XX External causes of morbidity and mortality	0.063	0.937
Z96 Presence of other functional implants	0.063	0.937
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.063	0.937
Chapter V Mental and behavioural disorders	0.063	0.937
Z92 Personal history of medical treatment	0.063	0.937
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.062	0.937
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.062	0.938
Z40-Z54 Persons encountering health services for specific procedures and health care	0.062	0.938
Chapter XXII Codes for special purposes	0.061	0.939
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.061	0.939
Chapter XVI Certain conditions originating in the perinatal period	0.061	0.939
Chapter XV Pregnancy, childbirth and the puerperium	0.061	0.939
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.061	0.939
Chapter XII Diseases of the skin and subcutaneous tissue	0.061	0.939
Chapter VIII Diseases of the ear and mastoid process	0.061	0.939
Chapter VI Diseases of the nervous system	0.061	0.939
Chapter I Certain infectious and parasitic diseases	0.061	0.939
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.061	0.939
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.061	0.939
Z95.1 Presence of aortocoronary bypass graft	0.060	0.940
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.060	0.940
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.060	0.940
Z98 Other postsurgical states	0.060	0.940
Z97 Presence of other devices	0.060	0.940
Z94 Transplanted organ and tissue status	0.060	0.940
Z93 Artificial opening status	0.060	0.940
Z91 Personal history of risk-factors, not elsewhere classified	0.060	0.940
Z89 Acquired absence of limb	0.060	0.940
Z85 Personal history of malignant neoplasm	0.060	0.940
Z84 Family history of other conditions	0.060	0.940
Z83 Family history of other specific disorders	0.060	0.940
Z81 Family history of mental and behavioural disorders	0.060	0.940
Z80 Family history of malignant neoplasm	0.060	0.940
Chapter VII Diseases of the eye and adnexa	0.060	0.940
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.059	0.941
Z86.6 Personal history of diseases of the nervous system and sense organs	0.059	0.941
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.058	0.942
R30-R39 Symptoms and signs involving the urinary system	0.058	0.942
N80-N98 Noninflammatory disorders of female genital tract	0.056	0.944
R95-R99 Ill-defined and unknown causes of mortality	0.055	0.944
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.055	0.944
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.055	0.944
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.055	0.944
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.055	0.944
R47-R49 Symptoms and signs involving speech and voice	0.055	0.944
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.055	0.944
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.055	0.944
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.055	0.944
Z95.5 Presence of coronary angioplasty implant and graft	0.055	0.945
E00-E07 Disorders of thyroid gland	0.055	0.945
K50-K52 Noninfective enteritis and colitis	0.055	0.945
Z86.7 Personal history of diseases of the circulatory system	0.054	0.946
J09-J18 Influenza and pneumonia	0.054	0.946
Z87.1 Personal history of diseases of the digestive system	0.053	0.947
Z86.5 Personal history of other mental and behavioural disorders	0.053	0.947
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.053	0.947
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.053	0.947
Z86.1 Personal history of infectious and parasitic diseases	0.053	0.947
Z86.0 Personal history of other neoplasms	0.053	0.947
K90-K93 Other diseases of the digestive system	0.053	0.947
R69 Unknown and unspecified causes of morbidity	0.053	0.947
J20-J22 Other acute lower respiratory infections	0.052	0.948
R55 Syncope and collapse	0.052	0.948
Z72 Problems related to lifestyle	0.052	0.948
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.052	0.948
Z37 Outcome of delivery	0.052	0.948
R07 Pain in throat and chest	0.052	0.948
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.051	0.949
Z95.8 Presence of other cardiac and vascular implants and grafts	0.051	0.949
Z95.4 Presence of other heart-valve replacement	0.051	0.949
Z95.3 Presence of xenogenic heart valve	0.051	0.949
Z95.2 Presence of prosthetic heart valve	0.051	0.949
Z95.0 Presence of cardiac pacemaker	0.051	0.949
Z87.4 Personal history of diseases of the genito-urinary system	0.051	0.949
K55-K64 Other diseases of intestines	0.051	0.949
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.050	0.949
N30-N39 Other diseases of urinary system	0.050	0.950
Z90.4 Acquired absence of other parts of digestive tract	0.050	0.950
I20-I25 Ischaemic heart diseases	0.050	0.950
K20-K31 Diseases of oesophagus, stomach and duodenum	0.049	0.950
M70-M79 Other soft tissue disorders	0.049	0.951
N99-N99 Other disorders of the genitourinary system	0.049	0.951
N70-N77 Inflammatory diseases of female pelvic organs	0.049	0.951
N60-N64 Disorders of breast	0.049	0.951
N40-N51 Diseases of male genital organs	0.049	0.951
N25-N29 Other disorders of kidney and ureter	0.049	0.951
N20-N23 Urolithiasis	0.049	0.951
N17-N19 Renal failure	0.049	0.951
N10-N16 Renal tubulo-interstitial diseases	0.049	0.951
N00-N08 Glomerular diseases	0.049	0.951
K70-K77 Diseases of liver	0.049	0.951
K65-K67 Diseases of peritoneum	0.049	0.951
K35-K38 Diseases of appendix	0.049	0.951
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.049	0.951
J95-J99 Other diseases of the respiratory system	0.049	0.951
J90-J94 Other diseases of pleura	0.049	0.951
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.049	0.951
J80-J84 Other respiratory diseases principally affecting the interstitium	0.049	0.951
J60-J70 Lung diseases due to external agents	0.049	0.951
J30-J39 Other diseases of upper respiratory tract	0.049	0.951
J00-J06 Acute upper respiratory infections	0.049	0.951
J40-J47 Chronic lower respiratory diseases	0.049	0.951
Z96.6 Presence of orthopaedic joint implants	0.049	0.951
C60-C63 Malignant neoplasms of male genital organs	0.049	0.951
R11 Nausea and vomiting	0.049	0.951
Z87.8 Personal history of other specified conditions	0.048	0.952
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.048	0.952
Z87.6 Personal history of certain conditions arising in the perinatal period	0.048	0.952
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.048	0.952
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.048	0.952
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.048	0.952
Z87.0 Personal history of diseases of the respiratory system	0.048	0.952
Z92.2 Personal history of long-term (current) use of other medicaments	0.048	0.952
F30-F39 Mood [affective] disorders	0.048	0.952
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.048	0.952
E65-E68 Obesity and other hyperalimentation	0.047	0.952
E50-E64 Other nutritional deficiencies	0.047	0.952
E40-E46 Malnutrition	0.047	0.952
E20-E35 Disorders of other endocrine glands	0.047	0.952
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.047	0.952
Z76 Persons encountering health services in other circumstances	0.047	0.953
Z75 Problems related to medical facilities and other health care	0.047	0.953
Z74 Problems related to care-provider dependency	0.047	0.953
Z73 Problems related to life-management difficulty	0.047	0.953
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.047	0.953
Z70 Counselling related to sexual attitude, behaviour and orientation	0.047	0.953
Z39 Postpartum care and examination	0.047	0.953
Z38 Liveborn infants according to place of birth	0.047	0.953
Z36 Antenatal screening	0.047	0.953
Z35 Supervision of high-risk pregnancy	0.047	0.953
Z34 Supervision of normal pregnancy	0.047	0.953
Z32 Pregnancy examination and test	0.047	0.953
Z31 Procreative management	0.047	0.953
Z30 Contraceptive management	0.047	0.953
Z33 Pregnant state, incidental	0.047	0.953
E70-E90 Metabolic disorders	0.047	0.953
N84 Polyp of female genital tract	0.047	0.953
E03 Other hypothyroidism	0.047	0.953
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.047	0.953
R68 Other general symptoms and signs	0.047	0.953
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.047	0.953
R63 Symptoms and signs concerning food and fluid intake	0.047	0.953
R62 Lack of expected normal physiological development	0.047	0.953
R61 Hyperhidrosis	0.047	0.953
R60 Oedema, not elsewhere classified	0.047	0.953
R59 Enlarged lymph nodes	0.047	0.953
R57 Shock, not elsewhere classified	0.047	0.953
R56 Convulsions, not elsewhere classified	0.047	0.953
R52 Pain, not elsewhere classified	0.047	0.953
R50 Fever of unknown origin	0.047	0.953
R64 Cachexia	0.047	0.953
R58 Haemorrhage, not elsewhere classified	0.047	0.953
R54 Senility	0.047	0.953
R53 Malaise and fatigue	0.047	0.953
R51 Headache	0.047	0.953
R33 Retention of urine	0.047	0.953
Z13 Special screening examination for other diseases and disorders	0.047	0.953
Z12 Special screening examination for neoplasms	0.047	0.953
Z11 Special screening examination for infectious and parasitic diseases	0.047	0.953
Z10 Routine general health check-up of defined subpopulation	0.047	0.953
Z08 Follow-up examination after treatment for malignant neoplasm	0.047	0.953
Z04 Examination and observation for other reasons	0.047	0.953
Z03 Medical observation and evaluation for suspected diseases and conditions	0.047	0.953
Z02 Examination and encounter for administrative purposes	0.047	0.953
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.047	0.953
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.047	0.953
D60-D64 Aplastic and other anaemias	0.046	0.954
I95-I99 Other and unspecified disorders of the circulatory system	0.046	0.954
I70-I79 Diseases of arteries, arterioles and capillaries	0.046	0.954
I60-I69 Cerebrovascular diseases	0.046	0.954
I30-I52 Other forms of heart disease	0.046	0.954
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.046	0.954
I05-I09 Chronic rheumatic heart diseases	0.046	0.954
I00-I02 Acute rheumatic fever	0.046	0.954
D37-D48 Neoplasms of uncertain or unknown behaviour	0.046	0.954
D10-D36 Benign neoplasms	0.046	0.954
D00-D09 In situ neoplasms	0.046	0.954
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.046	0.954
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.046	0.954
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.046	0.954
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.046	0.954
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.046	0.954
C64-C68 Malignant neoplasms of urinary tract	0.046	0.954
C51-C58 Malignant neoplasms of female genital organs	0.046	0.954
C50-C50 Malignant neoplasm of breast	0.046	0.954
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.046	0.954
C43-C44 Melanoma and other malignant neoplasms of skin	0.046	0.954
C40-C41 Malignant neoplasms of bone and articular cartilage	0.046	0.954
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.046	0.954
C15-C26 Malignant neoplasms of digestive organs	0.046	0.954
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.046	0.954
I10-I15 Hypertensive diseases	0.046	0.954
Z90.8 Acquired absence of other organs	0.046	0.954
Z90.7 Acquired absence of genital organ(s)	0.046	0.954
Z90.6 Acquired absence of other parts of urinary tract	0.046	0.954
Z90.5 Acquired absence of kidney	0.046	0.954
Z90.3 Acquired absence of part of stomach	0.046	0.954
Z90.2 Acquired absence of lung [part of]	0.046	0.954
Z90.1 Acquired absence of breast(s)	0.046	0.954
Z90.0 Acquired absence of part of head and neck	0.046	0.954
Z51 Other medical care	0.046	0.954
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.045	0.954
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.045	0.954
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.045	0.954
Y60-Y69 Misadventures to patients during surgical and medical care	0.045	0.954
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.045	0.954
Y35-Y36 Legal intervention and operations of war	0.045	0.954
Y10-Y34 Event of undetermined intent	0.045	0.954
Y00-Y09 Assault	0.045	0.954
X85-X99 Assault	0.045	0.954
X60-X84 Intentional self-harm	0.045	0.954
X58-X59 Accidental exposure to other and unspecified factors	0.045	0.954
X50-X57 Overexertion, travel and privation	0.045	0.954
X40-X49 Accidental poisoning by and exposure to noxious substances	0.045	0.954
X30-X39 Exposure to forces of nature	0.045	0.954
X20-X29 Contact with venomous animals and plants	0.045	0.954
X10-X19 Contact with heat and hot substances	0.045	0.954
X00-X09 Exposure to smoke, fire and flames	0.045	0.954
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.045	0.954
W75-W84 Other accidental threats to breathing	0.045	0.954
W65-W74 Accidental drowning and submersion	0.045	0.954
W50-W64 Exposure to animate mechanical forces	0.045	0.954
W20-W49 Exposure to inanimate mechanical forces	0.045	0.954
W00-W19 Falls	0.045	0.954
V98-V99 Other and unspecified transport accidents	0.045	0.954
V95-V97 Air and space transport accidents	0.045	0.954
V90-V94 Water transport accidents	0.045	0.954
V80-V89 Other land transport accidents	0.045	0.954
V70-V79 Bus occupant injured in transport accident	0.045	0.954
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.045	0.954
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.045	0.954
V40-V49 Car occupant injured in transport accident	0.045	0.954
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.045	0.954
V20-V29 Motorcycle rider injured in transport accident	0.045	0.954
V10-V19 Pedal cyclist injured in transport accident	0.045	0.954
V01-V09 Pedestrian injured in transport accident	0.045	0.954
Z96.9 Presence of functional implant, unspecified	0.045	0.954
Z96.8 Presence of other specified functional implants	0.045	0.954
Z96.7 Presence of other bone and tendon implants	0.045	0.954
Z96.5 Presence of tooth-root and mandibular implants	0.045	0.954
Z96.4 Presence of endocrine implants	0.045	0.954
Z96.3 Presence of artificial larynx	0.045	0.954
Z96.2 Presence of otological and audiological implants	0.045	0.954
Z96.1 Presence of intraocular lens	0.045	0.954
Z96.0 Presence of urogenital implants	0.045	0.954
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.045	0.954
M91-M94 Chondropathies	0.045	0.954
M86-M90 Other osteopathies	0.045	0.954
M80-M85 Disorders of bone density and structure	0.045	0.954
M65-M68 Disorders of synovium and tendon	0.045	0.954
M60-M63 Disorders of muscles	0.045	0.954
M50-M54 Other dorsopathies	0.045	0.954
M45-M49 Spondylopathies	0.045	0.954
M40-M43 Deforming dorsopathies	0.045	0.954
M20-M25 Other joint disorders	0.045	0.954
M05-M14 Inflammatory polyarthropathies	0.045	0.954
M00-M03 Infectious arthropathies	0.045	0.954
F99-F99 Unspecified mental disorder	0.045	0.954
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.045	0.954
F80-F89 Disorders of psychological development	0.045	0.954
F70-F79 Mental retardation	0.045	0.954
F60-F69 Disorders of adult personality and behaviour	0.045	0.954
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.045	0.954
F40-F48 Neurotic, stress-related and somatoform disorders	0.045	0.954
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.045	0.954
F00-F09 Organic, including symptomatic, mental disorders	0.045	0.954
Z92.9 Personal history of medical treatment, unspecified	0.045	0.955
Z92.8 Personal history of other medical treatment	0.045	0.955
Z92.6 Personal history of chemotherapy for neoplastic disease	0.045	0.955
Z92.5 Personal history of rehabilitation measures	0.045	0.955
Z92.4 Personal history of major surgery, not elsewhere classified	0.045	0.955
Z92.3 Personal history of irradiation	0.045	0.955
Z92.0 Personal history of contraception	0.045	0.955
Z92.1 Personal history of long-term (current) use of anticoagulants	0.045	0.955
D80-D89 Certain disorders involving the immune mechanism	0.045	0.955
D70-D77 Other diseases of blood and blood-forming organs	0.045	0.955
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.045	0.955
D55-D59 Haemolytic anaemias	0.045	0.955
D50-D53 Nutritional anaemias	0.045	0.955
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.045	0.955
R06 Abnormalities of breathing	0.045	0.955
R04 Haemorrhage from respiratory passages	0.045	0.955
R03 Abnormal blood-pressure reading, without diagnosis	0.045	0.955
R01 Cardiac murmurs and other cardiac sounds	0.045	0.955
R00 Abnormalities of heart beat	0.045	0.955
R05 Cough	0.045	0.955
R02 Gangrene, not elsewhere classified	0.045	0.955
K52 Other non-infective gastro-enteritis and colitis	0.045	0.955
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.045	0.955
Z53 Persons encountering health services for specifie procedures, not carried out	0.045	0.955
Z54 Convalescence	0.045	0.955
Z52 Donors of organs and tissues	0.045	0.955
Z50 Care involving use of rehabilitation procedures	0.045	0.955
Z49 Care involving dialysis	0.045	0.955
Z48 Other surgical follow-up care	0.045	0.955
Z47 Other orthopaedic follow-up care	0.045	0.955
Z46 Fitting and adjustment of other devices	0.045	0.955
Z45 Adjustment and management of implanted device	0.045	0.955
Z44 Fitting and adjustment of external prosthetic device	0.045	0.955
Z43 Attention to artificial openings	0.045	0.955
Z42 Follow-up care involving plastic surgery	0.045	0.955
Z41 Procedures for purposes other than remedying health state	0.045	0.955
Z40 Prophylactic surgery	0.045	0.955
B99-B99 Other infectious diseases	0.044	0.956
B95-B98 Bacterial, viral and other infectious agents	0.044	0.956
B90-B94 Sequelae of infectious and parasitic diseases	0.044	0.956
B85-B89 Pediculosis, acariasis and other infestations	0.044	0.956
B65-B83 Helminthiases	0.044	0.956
B50-B64 Protozoal diseases	0.044	0.956
B35-B49 Mycoses	0.044	0.956
B25-B34 Other viral diseases	0.044	0.956
B20-B24 Human immunodeficiency virus [HIV] disease	0.044	0.956
B15-B19 Viral hepatitis	0.044	0.956
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.044	0.956
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.044	0.956
A80-A89 Viral infections of the central nervous system	0.044	0.956
A75-A79 Rickettsioses	0.044	0.956
A70-A74 Other diseases caused by chlamydiae	0.044	0.956
A65-A69 Other spirochaetal diseases	0.044	0.956
A50-A64 Infections with a predominantly sexual mode of transmission	0.044	0.956
A30-A49 Other bacterial diseases	0.044	0.956
A20-A28 Certain zoonotic bacterial diseases	0.044	0.956
A15-A19 Tuberculosis	0.044	0.956
A00-A09 Intestinal infectious diseases	0.044	0.956
G90-G99 Other disorders of the nervous system	0.044	0.956
G80-G83 Cerebral palsy and other paralytic syndromes	0.044	0.956
G70-G73 Diseases of myoneural junction and muscle	0.044	0.956
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.044	0.956
G50-G59 Nerve, nerve root and plexus disorders	0.044	0.956
G40-G47 Episodic and paroxysmal disorders	0.044	0.956
G35-G37 Demyelinating diseases of the central nervous system	0.044	0.956
G30-G32 Other degenerative diseases of the nervous system	0.044	0.956
G20-G26 Extrapyramidal and movement disorders	0.044	0.956
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.044	0.956
G00-G09 Inflammatory diseases of the central nervous system	0.044	0.956
H90-H95 Other disorders of ear	0.044	0.956
H80-H83 Diseases of inner ear	0.044	0.956
H65-H75 Diseases of middle ear and mastoid	0.044	0.956
H60-H62 Diseases of external ear	0.044	0.956
L80-L99 Other disorders of the skin and subcutaneous tissue	0.044	0.956
L60-L75 Disorders of skin appendages	0.044	0.956
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.044	0.956
L50-L54 Urticaria and erythema	0.044	0.956
L40-L45 Papulosquamous disorders	0.044	0.956
L20-L30 Dermatitis and eczema	0.044	0.956
L10-L14 Bullous disorders	0.044	0.956
L00-L08 Infections of the skin and subcutaneous tissue	0.044	0.956
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.044	0.956
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.044	0.956
T79-T79 Certain early complications of trauma	0.044	0.956
T66-T78 Other and unspecified effects of external causes	0.044	0.956
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.044	0.956
T36-T50 Poisoning by drugs, medicaments and biological substances	0.044	0.956
T33-T35 Frostbite	0.044	0.956
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.044	0.956
T26-T28 Burns and corrosions confined to eye and internal organs	0.044	0.956
T20-T25 Burns and corrosions of external body surface, specified by site	0.044	0.956
T15-T19 Effects of foreign body entering through natural orifice	0.044	0.956
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.044	0.956
T00-T07 Injuries involving multiple body regions	0.044	0.956
S90-S99 Injuries to the ankle and foot	0.044	0.956
S80-S89 Injuries to the knee and lower leg	0.044	0.956
S70-S79 Injuries to the hip and thigh	0.044	0.956
S60-S69 Injuries to the wrist and hand	0.044	0.956
S50-S59 Injuries to the elbow and forearm	0.044	0.956
S40-S49 Injuries to the shoulder and upper arm	0.044	0.956
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.044	0.956
S20-S29 Injuries to the thorax	0.044	0.956
S10-S19 Injuries to the neck	0.044	0.956
S00-S09 Injuries to the head	0.044	0.956
O94-O99 Other obstetric conditions, not elsewhere classified	0.044	0.956
O85-O92 Complications predominantly related to the puerperium	0.044	0.956
O80-O84 Delivery	0.044	0.956
O60-O75 Complications of labour and delivery	0.044	0.956
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.044	0.956
O20-O29 Other maternal disorders predominantly related to pregnancy	0.044	0.956
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.044	0.956
O00-O08 Pregnancy with abortive outcome	0.044	0.956
P90-P96 Other disorders originating in the perinatal period	0.044	0.956
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.044	0.956
P75-P78 Digestive system disorders of fetus and newborn	0.044	0.956
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.044	0.956
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.044	0.956
P35-P39 Infections specific to the perinatal period	0.044	0.956
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.044	0.956
P10-P15 Birth trauma	0.044	0.956
P05-P08 Disorders related to length of gestation and fetal growth	0.044	0.956
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.044	0.956
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.044	0.956
Q80-Q89 Other congenital malformations	0.044	0.956
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.044	0.956
Q60-Q64 Congenital malformations of the urinary system	0.044	0.956
Q50-Q56 Congenital malformations of genital organs	0.044	0.956
Q38-Q45 Other congenital malformations of the digestive system	0.044	0.956
Q35-Q37 Cleft lip and cleft palate	0.044	0.956
Q30-Q34 Congenital malformations of the respiratory system	0.044	0.956
Q20-Q28 Congenital malformations of the circulatory system	0.044	0.956
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.044	0.956
Q00-Q07 Congenital malformations of the nervous system	0.044	0.956
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.044	0.956
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.044	0.956
Z29 Need for other prophylactic measures	0.044	0.956
Z28 Immunisation not carried out	0.044	0.956
Z27 Need for immunisation against combinations of infectious diseases	0.044	0.956
Z26 Need for immunisation against other single infectious diseases	0.044	0.956
Z25 Need for immunisation against other single viral diseases	0.044	0.956
Z24 Need for immunisation against certain single viral diseases	0.044	0.956
Z23 Need for immunisation against single bacterial diseases	0.044	0.956
Z22 Carrier of infectious disease	0.044	0.956
Z20 Contact with and exposure to communicable diseases	0.044	0.956
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.044	0.956
Z65 Problems related to other psychosocial circumstances	0.044	0.956
Z64 Problems related to certain psychosocial circumstances	0.044	0.956
Z63 Other problems related to primary support group, including family circumstances	0.044	0.956
Z62 Other problems related to upbringing	0.044	0.956
Z61 Problems related to negative life events in childhood	0.044	0.956
Z60 Problems related to social environment	0.044	0.956
Z59 Problems related to housing and economic circumstances	0.044	0.956
Z58 Problems related to physical environment	0.044	0.956
Z57 Occupational exposure to risk-factors	0.044	0.956
Z56 Problems related to employment and unemployment	0.044	0.956
Z55 Problems related to education and literacy	0.044	0.956
J18 Pneumonia, organism unspecified	0.044	0.956
E10-E14 Diabetes mellitus	0.043	0.957
M15-M19 Arthrosis	0.043	0.957
R19 Other symptoms and signs involving the digestive system and abdomen	0.043	0.957
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.043	0.957
R18 Ascites	0.043	0.957
R17 Unspecified jaundice	0.043	0.957
R15 Faecal incontinence	0.043	0.957
R14 Flatulence and related conditions	0.043	0.957
R13 Dysphagia	0.043	0.957
R12 Heartburn	0.043	0.957
Z80.9 Family history of malignant neoplasm, unspecified	0.043	0.957
Z80.8 Family history of malignant neoplasm of other organs or systems	0.043	0.957
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.043	0.957
Z80.6 Family history of leukaemia	0.043	0.957
Z80.5 Family history of malignant neoplasm of urinary tract	0.043	0.957
Z80.4 Family history of malignant neoplasm of genital organs	0.043	0.957
Z80.3 Family history of malignant neoplasm of breast	0.043	0.957
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.043	0.957
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.043	0.957
Z80.0 Family history of malignant neoplasm of digestive organs	0.043	0.957
Z81.8 Family history of other mental and behavioural disorders	0.043	0.957
Z81.4 Family history of other substance abuse	0.043	0.957
Z81.3 Family history of other psychoactive substance abuse	0.043	0.957
Z81.2 Family history of tobacco abuse	0.043	0.957
Z81.1 Family history of alcohol abuse	0.043	0.957
Z81.0 Family history of mental retardation	0.043	0.957
Z83.7 Family history of diseases of the digestive system	0.043	0.957
Z83.6 Family history of diseases of the respiratory system	0.043	0.957
Z83.5 Family history of eye and ear disorders	0.043	0.957
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.043	0.957
Z83.3 Family history of diabetes mellitus	0.043	0.957
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.043	0.957
Z83.1 Family history of other infectious and parasitic diseases	0.043	0.957
Z83.0 Family history of human immunodeficiency virus [HIV]	0.043	0.957
Z84.8 Family history of other specified conditions	0.043	0.957
Z84.3 Family history of consanguinity	0.043	0.957
Z84.2 Family history of other diseases of the genito-urinary system	0.043	0.957
Z84.1 Family history of disorders of the kidney and ureter	0.043	0.957
Z84.0 Family history of diseases of the skin and subcutaneous tissue	0.043	0.957
Z85.0 Personal history of malignant neoplasm of digestive organs	0.043	0.957
Z85.9 Personal history of malignant neoplasm, unspecified	0.043	0.957
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.043	0.957
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.043	0.957
Z85.6 Personal history of leukaemia	0.043	0.957
Z85.5 Personal history of malignant neoplasm of urinary tract	0.043	0.957
Z85.4 Personal history of malignant neoplasm of genital organs	0.043	0.957
Z85.3 Personal history of malignant neoplasm of breast	0.043	0.957
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.043	0.957
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.043	0.957
Z89.9 Acquired absence of limb, unspecified	0.043	0.957
Z89.8 Acquired absence of upper and lower limbs [any level]	0.043	0.957
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.043	0.957
Z89.6 Acquired absence of leg above knee	0.043	0.957
Z89.5 Acquired absence of leg at or below knee	0.043	0.957
Z89.4 Acquired absence of foot and ankle	0.043	0.957
Z89.3 Acquired absence of both upper limbs [any level]	0.043	0.957
Z89.2 Acquired absence of upper limb above wrist	0.043	0.957
Z89.1 Acquired absence of hand and wrist	0.043	0.957

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations