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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1893217
log Bayes Factor = 16.5233
Chromosome 18   position 12,809,340  (GRCh37) Explore rs1893217 on Ensembl!
Variant rs1893217 is listed in the   GWAS Catalog   ⇪
Variant rs1893217 is part of Cluster X0236

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K50 Crohn's disease [regional enteritis]
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
D50 Iron deficiency anaemia
0.999 0.001 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
D50.9 Iron deficiency anaemia, unspecified
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.998 0.002 0.000
D51 Vitamin B12 deficiency anaemia
0.995 0.005 0.000
K50.9 Crohn's disease, unspecified
0.995 0.005 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
K90.0 Coeliac disease
0.994 0.006 0.000
K90 Intestinal malabsorption
0.993 0.007 0.000
K90-K93 Other diseases of the digestive system
0.992 0.008 0.000
# Top node
0.991 0.009 0.000
E11.3 With ophthalmic complications
0.990 0.010 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.989 0.011 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.988 0.012 0.000
E10.3 With ophthalmic complications
0.985 0.015 0.000
K51 Ulcerative colitis
0.984 0.016 0.000
K07 Dentofacial anomalies [including malocclusion]
0.973 0.027 0.000
K50.1 Crohn's disease of large intestine
0.973 0.027 0.000
K11 Diseases of salivary glands
0.972 0.028 0.000
K50.0 Crohn's disease of small intestine
0.972 0.028 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.970 0.030 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.969 0.031 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.969 0.031 0.000
E27 Other disorders of adrenal gland
0.962 0.038 0.000
E10.1 With ketoacidosis
0.954 0.046 0.000
K07.3 Anomalies of tooth position
0.953 0.047 0.000
K51.4 Pseudopolyposis of colon
0.946 0.054 0.000
K51.9 Ulcerative colitis, unspecified
0.933 0.067 0.000
E11.1 With ketoacidosis
0.930 0.070 0.000
D50.8 Other iron deficiency anaemias
0.922 0.078 0.000
Q60-Q64 Congenital malformations of the urinary system
0.917 0.083 0.000
Chapter VII Diseases of the eye and adnexa
0.914 0.086 0.000
E21.0 Primary hyperparathyroidism
0.912 0.088 0.000
K11.2 Sialoadenitis
0.904 0.096 0.000
H30-H36 Disorders of choroid and retina
0.904 0.096 0.000
E24 Cushing's syndrome
0.899 0.101 0.000
H36 Retinal disorders in diseases classified elsewhere
0.898 0.102 0.000
E27.9 Disorder of adrenal gland, unspecified
0.896 0.104 0.000
H36.0 Diabetic retinopathy
0.894 0.106 0.000
Chapter XX External causes of morbidity and mortality
0.890 0.110 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.888 0.112 0.000
E14 Unspecified diabetes mellitus
0.882 0.118 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.882 0.118 0.000
K09 Cysts of oral region, not elsewhere classified
0.882 0.118 0.000
K50.8 Other Crohn's disease
0.871 0.129 0.000
K11.5 Sialolithiasis
0.870 0.130 0.000
E11.6 With other specified complications
0.870 0.130 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.868 0.132 0.000
E10.4 With neurological complications
0.867 0.133 0.000
Q50-Q56 Congenital malformations of genital organs
0.865 0.135 0.000
H43-H45 Disorders of vitreous body and globe
0.863 0.137 0.000
E10.6 With other specified complications
0.855 0.145 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.847 0.153 0.000
E27.8 Other specified disorders of adrenal gland
0.844 0.156 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.844 0.156 0.000
E23 Hypofunction and other disorders of pituitary gland
0.842 0.158 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.839 0.161 0.000
V40-V49 Car occupant injured in transport accident
0.837 0.163 0.000
E11.5 With peripheral circulatory complications
0.829 0.171 0.000
E03.1 Congenital hypothyroidism without goitre
0.829 0.171 0.000
Q21 Congenital malformations of cardiac septa
0.818 0.182 0.000
K12 Stomatitis and related lesions
0.818 0.182 0.000
E21.3 Hyperparathyroidism, unspecified
0.816 0.184 0.000
E29 Testicular dysfunction
0.815 0.185 0.000
K11.9 Disease of salivary gland, unspecified
0.812 0.188 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.810 0.190 0.000
H43 Disorders of vitreous body
0.807 0.193 0.000
E34 Other endocrine disorders
0.807 0.193 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.804 0.196 0.000
K11.1 Hypertrophy of salivary gland
0.802 0.198 0.000
H34 Retinal vascular occlusions
0.798 0.202 0.000
E14.9 Without complications
0.798 0.202 0.000
K09.0 Developmental odontogenic cysts
0.794 0.206 0.000
V48 Car occupant injured in noncollision transport accident
0.793 0.207 0.000
Q27 Other congenital malformations of peripheral vascular system
0.791 0.209 0.000
E24.9 Cushing's syndrome, unspecified
0.789 0.211 0.000
Q63 Other congenital malformations of kidney
0.788 0.212 0.000
Chapter XXII Codes for special purposes
0.787 0.213 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.786 0.214 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.784 0.216 0.000
E21.4 Other specified disorders of parathyroid gland
0.783 0.217 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.782 0.218 0.000
Q90 Down's syndrome
0.778 0.222 0.000
K07.4 Malocclusion, unspecified
0.775 0.225 0.000
K90.8 Other intestinal malabsorption
0.771 0.229 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.769 0.231 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.768 0.232 0.000
E13 Other specified diabetes mellitus
0.766 0.234 0.000
Q21.0 Ventricular septal defect
0.765 0.235 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.765 0.235 0.000
K07.9 Dentofacial anomaly, unspecified
0.765 0.235 0.000
E50-E64 Other nutritional deficiencies
0.764 0.236 0.000
V48.4 Person injured while boarding or alighting
0.762 0.238 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.762 0.238 0.000
V98-V99 Other and unspecified transport accidents
0.761 0.239 0.000
K07.1 Anomalies of jaw-cranial base relationship
0.759 0.241 0.000
W50-W64 Exposure to animate mechanical forces
0.758 0.242 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.758 0.242 0.000
K12.1 Other forms of stomatitis
0.756 0.244 0.000
E11.2 With renal complications
0.754 0.246 0.000
E10.8 With unspecified complications
0.753 0.247 0.000
Q60.0 Renal agenesis, unilateral
0.752 0.248 0.000
K14 Diseases of tongue
0.751 0.249 0.000
E14.1 With ketoacidosis
0.749 0.251 0.000
K51.5 Mucosal proctocolitis
0.748 0.252 0.000
K11.3 Abscess of salivary gland
0.748 0.252 0.000
H43.1 Vitreous haemorrhage
0.748 0.252 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.743 0.256 0.000
E22 Hyperfunction of pituitary gland
0.742 0.258 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.740 0.260 0.000
Q66 Congenital deformities of feet
0.740 0.260 0.000
H21 Other disorders of iris and ciliary body
0.740 0.260 0.000
K07.0 Major anomalies of jaw size
0.740 0.260 0.000
Q52 Other congenital malformations of female genitalia
0.739 0.261 0.000
Y57 Other and unspecified drugs and medicaments
0.738 0.262 0.000
E40-E46 Malnutrition
0.734 0.265 0.000
K00 Disorders of tooth development and eruption
0.731 0.269 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.729 0.271 0.000
K04 Diseases of pulp and periapical tissues
0.729 0.271 0.000
H33 Retinal detachments and breaks
0.729 0.271 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.728 0.272 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.727 0.273 0.000
Q35-Q37 Cleft lip and cleft palate
0.727 0.273 0.000
V10-V19 Pedal cyclist injured in transport accident
0.727 0.273 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.723 0.277 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.722 0.278 0.000
Q60.2 Renal agenesis, unspecified
0.722 0.278 0.000
V90-V94 Water transport accidents
0.721 0.279 0.000
K90.9 Intestinal malabsorption, unspecified
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E31 Polyglandular dysfunction
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
D50.1 Sideropenic dysphagia
0.716 0.284 0.000
Q40 Other congenital malformations of upper alimentary tract
0.716 0.284 0.000
E11.7 With multiple complications
0.715 0.285 0.000
Q74 Other congenital malformations of limb(s)
0.715 0.285 0.000
E23.6 Other disorders of pituitary gland
0.715 0.285 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.714 0.286 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.714 0.286 0.000
D51.2 Transcobalamin II deficiency
0.714 0.286 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.714 0.286 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.712 0.288 0.000
K90.3 Pancreatic steatorrhoea
0.712 0.288 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.712 0.288 0.000
K90.1 Tropical sprue
0.712 0.288 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.711 0.288 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.710 0.290 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.710 0.290 0.000
K03 Other diseases of hard tissues of teeth
0.709 0.291 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.709 0.291 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.708 0.292 0.000
H33.5 Other retinal detachments
0.706 0.294 0.000
H44 Disorders of globe
0.706 0.294 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.705 0.295 0.000
E14.4 With neurological complications
0.703 0.297 0.000
E24.0 Pituitary-dependent Cushing's disease
0.703 0.297 0.000
Y44 Agents primarily affecting blood constituents
0.702 0.298 0.000
H50 Other strabismus
0.702 0.298 0.000
H21.8 Other specified disorders of iris and ciliary body
0.701 0.298 0.000
Q39 Congenital malformations of oesophagus
0.701 0.299 0.000
Q90.9 Down's syndrome, unspecified
0.700 0.300 0.000
Y45.2 Propionic acid derivatives
0.700 0.300 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.698 0.302 0.000
K07.8 Other dentofacial anomalies
0.697 0.302 0.000
K07.5 Dentofacial functional abnormalities
0.697 0.302 0.000
K11.4 Fistula of salivary gland
0.697 0.303 0.000
K11.0 Atrophy of salivary gland
0.697 0.303 0.000
Q96 Turner's syndrome
0.697 0.303 0.000
E21.2 Other hyperparathyroidism
0.695 0.305 0.000
E27.5 Adrenomedullary hyperfunction
0.690 0.310 0.000
E27.0 Other adrenocortical overactivity
0.690 0.310 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.689 0.311 0.000
E06 Thyroiditis
0.689 0.311 0.000
E10.5 With peripheral circulatory complications
0.688 0.312 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.687 0.313 0.000
E20 Hypoparathyroidism
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.683 0.316 0.000
E24.2 Drug-induced Cushing's syndrome
0.683 0.317 0.000
E29.1 Testicular hypofunction
0.683 0.317 0.000
K14.8 Other diseases of tongue
0.681 0.319 0.000
Q65 Congenital deformities of hip
0.681 0.319 0.000
H16 Keratitis
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.320 0.000
E53 Deficiency of other B group vitamins
0.679 0.321 0.000
K11.8 Other diseases of salivary glands
0.678 0.322 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.677 0.322 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.676 0.324 0.000
K05 Gingivitis and periodontal diseases
0.675 0.325 0.000
X10-X19 Contact with heat and hot substances
0.675 0.325 0.000
E11.8 With unspecified complications
0.673 0.327 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.673 0.327 0.000
E10.0 With coma
0.669 0.331 0.000
V99 Unspecified transport accident
0.669 0.331 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.668 0.332 0.000
K04.8 Radicular cyst
0.667 0.333 0.000
H34.1 Central retinal artery occlusion
0.666 0.334 0.000
Y59 Other and unspecified vaccines and biological substances
0.666 0.334 0.000
E11.0 With coma
0.665 0.334 0.000
Q51 Congenital malformations of uterus and cervix
0.665 0.335 0.000
E07 Other disorders of thyroid
0.665 0.335 0.000
E23.7 Disorder of pituitary gland, unspecified
0.665 0.335 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.664 0.336 0.000
D52 Folate deficiency anaemia
0.664 0.336 0.000
V01-V09 Pedestrian injured in transport accident
0.660 0.340 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.658 0.342 0.000
Y00-Y09 Assault
0.658 0.342 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.657 0.343 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.657 0.343 0.000
E34.8 Other specified endocrine disorders
0.654 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.649 0.351 0.000
H34.2 Other retinal artery occlusions
0.649 0.351 0.000
Q52.5 Fusion of labia
0.648 0.352 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.648 0.352 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.648 0.352 0.000
E26 Hyperaldosteronism
0.647 0.353 0.000
K11.7 Disturbances of salivary secretion
0.647 0.353 0.000
H33.2 Serous retinal detachment
0.647 0.353 0.000
W75-W84 Other accidental threats to breathing
0.646 0.354 0.000
E24.8 Other Cushing's syndrome
0.645 0.355 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.645 0.355 0.000
E24.3 Ectopic ACTH syndrome
0.645 0.355 0.000
E24.1 Nelson's syndrome
0.645 0.355 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.644 0.356 0.000
H43.9 Disorder of vitreous body, unspecified
0.644 0.356 0.000
H49 Paralytic strabismus
0.644 0.356 0.000
Q25 Congenital malformations of great arteries
0.643 0.357 0.000
K12.0 Recurrent oral aphthae
0.643 0.357 0.000
Y57.8 Other drugs and medicaments
0.641 0.359 0.000
H30 Chorioretinal inflammation
0.641 0.359 0.000
Q00-Q07 Congenital malformations of the nervous system
0.640 0.360 0.000
H43.8 Other disorders of vitreous body
0.640 0.360 0.000
Y79.2 Prosthetic and other implants, materials and accessory devices
0.638 0.362 0.000
Y35-Y36 Legal intervention and operations of war
0.638 0.362 0.000
X85-X99 Assault
0.638 0.362 0.000
X30-X39 Exposure to forces of nature
0.638 0.362 0.000
W65-W74 Accidental drowning and submersion
0.638 0.362 0.000
V95-V97 Air and space transport accidents
0.638 0.362 0.000
V70-V79 Bus occupant injured in transport accident
0.638 0.362 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.638 0.362 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.638 0.362 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.638 0.362 0.000
X00-X09 Exposure to smoke, fire and flames
0.638 0.362 0.000
E10.2 With renal complications
0.637 0.363 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.637 0.363 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.637 0.363 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.637 0.363 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.637 0.363 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.637 0.363 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.637 0.363 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.637 0.363 0.000
Q27.3 Peripheral arteriovenous malformation
0.636 0.364 0.000
E34.0 Carcinoid syndrome
0.635 0.365 0.000
Q45 Other congenital malformations of digestive system
0.633 0.367 0.000
E14.7 With multiple complications
0.632 0.367 0.000
E14.5 With peripheral circulatory complications
0.632 0.367 0.000
E14.2 Withrenal complications
0.632 0.367 0.000
E14.0 With coma
0.632 0.367 0.000
E23.0 Hypopituitarism
0.632 0.368 0.000
Q26 Congenital malformations of great veins
0.632 0.368 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.632 0.368 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.632 0.368 0.000
K09.9 Cyst of oral region, unspecified
0.630 0.370 0.000
K07.6 Temporomandibular joint disorders
0.629 0.370 0.000
K51.8 Other ulcerative colitis
0.629 0.371 0.000
E05.9 Thyrotoxicosis, unspecified
0.629 0.371 0.000
K11.6 Mucocele of salivary gland
0.626 0.374 0.000
Y10-Y34 Event of undetermined intent
0.625 0.375 0.000
K07.2 Anomalies of dental arch relationship
0.624 0.376 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.622 0.378 0.000
Q75 Other congenital malformations of skull and face bones
0.622 0.378 0.000
Q73 Reduction defects of unspecified limb
0.622 0.378 0.000
Q72 Reduction defects of lower limb
0.622 0.378 0.000
Q71 Reduction defects of upper limb
0.622 0.378 0.000
Q70 Syndactyly
0.622 0.378 0.000
Q69 Polydactyly
0.622 0.378 0.000
Q68 Other congenital musculoskeletal deformities
0.622 0.378 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.622 0.378 0.000
Q63.0 Accessory kidney
0.622 0.378 0.000
Q63.2 Ectopic kidney
0.622 0.378 0.000
Q66.8 Other congenital deformities of feet
0.621 0.379 0.000
Y41.5 Antiviral drugs
0.621 0.379 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.621 0.379 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.620 0.379 0.000
Q55 Other congenital malformations of male genital organs
0.620 0.379 0.000
E27.1 Primary adrenocortical insufficiency
0.620 0.380 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.620 0.380 0.000
K52 Other non-infective gastro-enteritis and colitis
0.620 0.380 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.619 0.381 0.000
Q21.1 Atrial septal defect
0.619 0.381 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.619 0.381 0.000
E53.8 Deficiency of other specified B group vitamins
0.619 0.381 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.616 0.384 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.616 0.384 0.000
H18 Other disorders of cornea
0.616 0.384 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.615 0.385 0.000
K09.1 Developmental (nonodontogenic) cysts of oral region
0.615 0.385 0.000
Y44.2 Anticoagulants
0.612 0.388 0.000
E03.8 Other specified hypothyroidism
0.610 0.389 0.000
K00.0 Anodontia
0.610 0.390 0.000
K51.2 Ulcerative (chronic) proctitis
0.610 0.390 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.609 0.391 0.000
Q43 Other congenital malformations of intestine
0.608 0.392 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.607 0.392 0.000
Q60.6 Potter's syndrome
0.607 0.393 0.000
Q60.5 Renal hypoplasia, unspecified
0.607 0.393 0.000
Q60.4 Renal hypoplasia, bilateral
0.607 0.393 0.000
Q60.3 Renal hypoplasia, unilateral
0.607 0.393 0.000
Q60.1 Renal agenesis, bilateral
0.607 0.393 0.000
Q64 Other congenital malformations of urinary system
0.607 0.393 0.000
E28 Ovarian dysfunction
0.607 0.393 0.000
E14.8 With unspecified complications
0.606 0.394 0.000
Y58 Bacterial vaccines
0.605 0.395 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.605 0.395 0.000
E14.6 With other specified complications
0.605 0.395 0.000
Q40.3 Congenital malformation of stomach, unspecified
0.605 0.395 0.000
Q53 Undescended testicle
0.604 0.396 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.604 0.396 0.000
E23.1 Drug-induced hypopituitarism
0.604 0.396 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.603 0.397 0.000
Q39.4 Oesophageal web
0.603 0.397 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.602 0.398 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.602 0.398 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.600 0.399 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.600 0.400 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.600 0.400 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.600 0.400 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.600 0.400 0.000
V41 Car occupant injured in collision with pedal cycle
0.600 0.400 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.600 0.400 0.000
Q78 Other osteochondrodysplasias
0.600 0.400 0.000
V93 Accident on board watercraft without accident to watercraft, not causing drowning and submersion
0.599 0.401 0.000
E13.9 Without complications
0.598 0.402 0.000
V43.9 Unspecified car occupant injured in traffic accident
0.598 0.402 0.000
H20 Iridocyclitis
0.598 0.402 0.000
Q76 Congenital malformations of spine and bony thorax
0.598 0.402 0.000
D53 Other nutritional anaemias
0.596 0.403 0.000
E22.1 Hyperprolactinaemia
0.596 0.404 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.594 0.405 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.594 0.405 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.594 0.406 0.000
H34.8 Other retinal vascular occlusions
0.589 0.411 0.000
H50.9 Strabismus, unspecified
0.587 0.413 0.000
D68 Other coagulation defects
0.587 0.413 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.587 0.413 0.000
Q21.8 Other congenital malformations of cardiac septa
0.587 0.413 0.000
Q21.4 Aortopulmonary septal defect
0.587 0.413 0.000
Q21.3 Tetralogy of Fallot
0.587 0.413 0.000
Q21.2 Atrioventricular septal defect
0.587 0.413 0.000
H34.9 Retinal vascular occlusion, unspecified
0.586 0.414 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.586 0.414 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.585 0.415 0.000
E29.9 Testicular dysfunction, unspecified
0.584 0.416 0.000
E29.8 Other testicular dysfunction
0.584 0.416 0.000
E29.0 Testicular hyperfunction
0.584 0.416 0.000
H44.4 Hypotony of eye
0.584 0.416 0.000
Y41.0 Sulphonamides
0.584 0.416 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.584 0.416 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.583 0.417 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.583 0.417 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.581 0.419 0.000
Y80 Physical medicine devices associated with adverse incidents
0.581 0.419 0.000
Y78 Radiological devices associated with adverse incidents
0.581 0.419 0.000
Y75 Neurological devices associated with adverse incidents
0.581 0.419 0.000
Y74 General hospital and personal-use devices associated with adverse incidents
0.581 0.419 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.581 0.419 0.000
Y72 Otorhinolaryngological devices associated with adverse incidents
0.581 0.419 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.581 0.419 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.580 0.420 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.580 0.420 0.000
K10 Other diseases of jaws
0.579 0.421 0.000
H43.0 Vitreous prolapse
0.579 0.421 0.000
K04.5 Chronic apical periodontitis
0.579 0.421 0.000
H50.0 Convergent concomitant strabismus
0.579 0.421 0.000
E34.5 Androgen resistance syndrome
0.578 0.421 0.000
E34.4 Constitutional tall stature
0.578 0.421 0.000
E34.3 Short stature, not elsewhere classified
0.578 0.421 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.578 0.421 0.000
E34.1 Other hypersecretion of intestinal hormones
0.578 0.421 0.000
H44.1 Other endophthalmitis
0.578 0.422 0.000
Q66.9 Congenital deformity of feet, unspecified
0.577 0.423 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.577 0.423 0.000
Q80-Q89 Other congenital malformations
0.576 0.424 0.000
E27.2 Addisonian crisis
0.575 0.425 0.000
H31 Other disorders of choroid
0.575 0.425 0.000
E11.4 With neurological complications
0.572 0.428 0.000
H34.0 Transient retinal artery occlusion
0.572 0.428 0.000
Y45.5 4-Aminophenol derivatives
0.571 0.428 0.000
Y77.2 Prosthetic and other implants, materials and accessory devices
0.571 0.429 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.571 0.429 0.000
X50 Overexertion and strenuous or repetitive movements
0.571 0.429 0.000
E05.8 Other thyrotoxicosis
0.570 0.430 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.570 0.430 0.000
W57.8 Other specified place
0.569 0.431 0.000
V48.5 Driver injured in traffic accident
0.569 0.431 0.000
V48.9 Unspecified car occupant injured in traffic accident
0.569 0.431 0.000
V48.7 Person on outside of vehicle injured in traffic accident
0.569 0.431 0.000
V48.6 Passenger injured in traffic accident
0.569 0.431 0.000
V48.3 Unspecified car occupant injured in nontraffic accident
0.569 0.431 0.000
V48.2 Person on outside of vehicle injured in nontraffic accident
0.569 0.431 0.000
V48.1 Passenger injured in nontraffic accident
0.569 0.431 0.000
V48.0 Driver injured in nontraffic accident
0.569 0.431 0.000
Y57.5 X-ray contrast media
0.569 0.431 0.000
K05.1 Chronic gingivitis
0.568 0.432 0.000
Y48 Anaesthetics and therapeutic gases
0.567 0.432 0.000
Q27.4 Congenital phlebectasia
0.567 0.433 0.000
Q27.2 Other congenital malformations of renal artery
0.567 0.433 0.000
Q27.1 Congenital renal artery stenosis
0.567 0.433 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.567 0.433 0.000
W55 Bitten or struck by other mammals
0.567 0.433 0.000
V80-V89 Other land transport accidents
0.565 0.435 0.000
K09.2 Other cysts of jaw
0.565 0.435 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.565 0.435 0.000
Q63.8 Other specified congenital malformations of kidney
0.565 0.435 0.000
Q63.3 Hyperplastic and giant kidney
0.565 0.435 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.565 0.435 0.000
H16.4 Corneal neovascularisation
0.564 0.436 0.000
H21.2 Degeneration of iris and ciliary body
0.563 0.437 0.000
Q28 Other congenital malformations of circulatory system
0.562 0.438 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.562 0.438 0.000
D55-D59 Haemolytic anaemias
0.561 0.439 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.561 0.439 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.560 0.440 0.000
Q96.9 Turner's syndrome, unspecified
0.560 0.440 0.000
H43.3 Other vitreous opacities
0.559 0.440 0.000
Y45.0 Opioids and related analgesics
0.558 0.442 0.000
Q90.2 Trisomy 21, translocation
0.558 0.442 0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)
0.558 0.442 0.000
Q90.0 Trisomy 21, meiotic nondisjunction
0.558 0.442 0.000
Q40.2 Other specified congenital malformations of stomach
0.555 0.445 0.000
H51 Other disorders of binocular movement
0.554 0.446 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.553 0.447 0.000
Q62.5 Duplication of ureter
0.553 0.447 0.000
H49.2 Sixth [abducent] nerve palsy
0.552 0.448 0.000
K05.4 Periodontosis
0.552 0.448 0.000
Y45.4 Antirheumatics
0.551 0.448 0.000
D80-D89 Certain disorders involving the immune mechanism
0.551 0.449 0.000
H50.2 Vertical strabismus
0.551 0.449 0.000
H50.1 Divergent concomitant strabismus
0.550 0.450 0.000
E13.8 With unspecified complications
0.549 0.451 0.000
E13.7 With multiple complications
0.549 0.451 0.000
E13.6 With other specified complications
0.549 0.451 0.000
E13.5 With peripheral circulatory complications
0.549 0.451 0.000
E13.4 With neurological complications
0.549 0.451 0.000
E13.3 With ophthalmic complications
0.549 0.451 0.000
E13.2 With renal complications
0.549 0.451 0.000
E13.1 With ketoacidosis
0.549 0.451 0.000
E13.0 With coma
0.549 0.451 0.000
K06.1 Gingival enlargement
0.548 0.451 0.000
K06.0 Gingival recession
0.548 0.451 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.548 0.452 0.000
E63 Other nutritional deficiencies
0.548 0.452 0.000
E56 Other vitamin deficiencies
0.548 0.452 0.000
E51 Thiamine deficiency
0.548 0.452 0.000
E50 Vitamin A deficiency
0.548 0.452 0.000
E60 Dietary zinc deficiency
0.548 0.452 0.000
E59 Dietary selenium deficiency
0.548 0.452 0.000
E58 Dietary calcium deficiency
0.548 0.452 0.000
E54 Ascorbic acid deficiency
0.548 0.452 0.000
E52 Niacin deficiency [pellagra]
0.548 0.452 0.000
U80 Agent resistant to penicillin and related antibiotics
0.548 0.452 0.000
Q65.8 Other congenital deformities of hip
0.547 0.453 0.000
Y52 Agents primarily affecting the cardiovascular system
0.547 0.453 0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.547 0.453 0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament
0.546 0.454 0.000
Q50.5 Embryonic cyst of broad ligament
0.546 0.454 0.000
Q50.3 Other congenital malformations of ovary
0.546 0.454 0.000
Q50.2 Congenital torsion of ovary
0.546 0.454 0.000
Q50.1 Developmental ovarian cyst
0.546 0.454 0.000
Q50.0 Congenital absence of ovary
0.546 0.454 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.546 0.454 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.546 0.454 0.000
V98 Other specified transport accidents
0.545 0.454 0.000
E46 Unspecified protein-energy malnutrition
0.544 0.456 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.544 0.456 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.543 0.456 0.000
W59 Bitten or crushed by other reptiles
0.543 0.456 0.000
W58 Bitten or struck by crocodile or alligator
0.543 0.456 0.000
W56 Contact with marine animal
0.543 0.456 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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