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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs190627217
log Bayes Factor = 13.7219
Chromosome 17   position 45,811,915  (GRCh37) Explore rs190627217 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M15-M19 Arthrosis
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.992 0.008 0.000
M19 Other arthrosis
0.991 0.009 0.000
Z86 Personal history of certain other diseases
0.990 0.010 0.000
M51 Other intervertebral disk disorders
0.989 0.011 0.000
M25 Other joint disorders, not elsewhere classified
0.988 0.012 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.986 0.014 0.000
M19.9 Arthrosis, unspecified
0.984 0.016 0.000
M54 Dorsalgia
0.983 0.017 0.000
Z86.7 Personal history of diseases of the circulatory system
0.983 0.017 0.000
Chapter XIV Diseases of the genitourinary system
0.979 0.021 0.000
M51.2 Other specified intervertebral disk displacement
0.979 0.021 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.975 0.025 0.000
M54.5 Low back pain
0.975 0.025 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.974 0.026 0.000
N60-N64 Disorders of breast
0.974 0.026 0.000
M25.5 Pain in joint
0.970 0.030 0.000
Chapter II Neoplasms
0.966 0.034 0.000
O00-O08 Pregnancy with abortive outcome
0.956 0.044 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.954 0.046 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.951 0.049 0.000
M16 Coxarthrosis [arthrosis of hip]
0.949 0.051 0.000
M25.56 Pain in joint (Lower leg)
0.941 0.059 0.000
Chapter V Mental and behavioural disorders
0.936 0.064 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.936 0.064 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.932 0.068 0.000
N61 Inflammatory disorders of breast
0.930 0.070 0.000
C51-C58 Malignant neoplasms of female genital organs
0.925 0.075 0.000
Z92 Personal history of medical treatment
0.923 0.077 0.000
N64 Other disorders of breast
0.923 0.077 0.000
Z87 Personal history of other diseases and conditions
0.916 0.084 0.000
H30-H36 Disorders of choroid and retina
0.916 0.084 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.915 0.085 0.000
M54.57 Low back pain (Lumbosacral region)
0.909 0.091 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.908 0.092 0.000
O02 Other abnormal products of conception
0.904 0.096 0.000
S70-S79 Injuries to the hip and thigh
0.902 0.098 0.000
N60 Benign mammary dysplasia
0.899 0.101 0.000
G35 Multiple sclerosis
0.893 0.107 0.000
M16.1 Other primary coxarthrosis
0.892 0.108 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.887 0.113 0.000
M45-M49 Spondylopathies
0.887 0.113 0.000
N10-N16 Renal tubulo-interstitial diseases
0.882 0.118 0.000
H40-H42 Glaucoma
0.881 0.119 0.000
Z86.0 Personal history of other neoplasms
0.881 0.119 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.880 0.120 0.000
S80-S89 Injuries to the knee and lower leg
0.879 0.121 0.000
C56 Malignant neoplasm of ovary
0.875 0.125 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.873 0.127 0.000
H43-H45 Disorders of vitreous body and globe
0.868 0.132 0.000
O02.1 Missed abortion
0.867 0.133 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.865 0.135 0.000
H10-H13 Disorders of conjunctiva
0.863 0.137 0.000
M23 Internal derangement of knee
0.862 0.138 0.000
M54.59 Low back pain (Site unspecified)
0.860 0.140 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.858 0.142 0.000
H35 Other retinal disorders
0.854 0.146 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.853 0.147 0.000
G40-G47 Episodic and paroxysmal disorders
0.852 0.148 0.000
M31 Other necrotising vasculopathies
0.849 0.151 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.848 0.152 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.846 0.154 0.000
M25.4 Effusion of joint
0.845 0.155 0.000
Z42 Follow-up care involving plastic surgery
0.839 0.161 0.000
M25.7 Osteophyte
0.839 0.161 0.000
D00-D09 In situ neoplasms
0.837 0.163 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.834 0.166 0.000
O60-O75 Complications of labour and delivery
0.833 0.167 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.832 0.168 0.000
G70-G73 Diseases of myoneural junction and muscle
0.832 0.168 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.829 0.171 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.827 0.173 0.000
Z97 Presence of other devices
0.826 0.174 0.000
N64.9 Disorder of breast, unspecified
0.825 0.175 0.000
M16.0 Primary coxarthrosis, bilateral
0.824 0.176 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.824 0.176 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.824 0.176 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.822 0.178 0.000
M25.54 Pain in joint (Hand)
0.817 0.183 0.000
Chapter XXII Codes for special purposes
0.817 0.183 0.000
M54.56 Low back pain (Lumbar region)
0.817 0.183 0.000
M54.4 Lumbago with sciatica
0.816 0.184 0.000
N60.0 Solitary cyst of breast
0.814 0.186 0.000
M30 Polyarteritis nodosa and related conditions
0.813 0.187 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.812 0.188 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.810 0.190 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.809 0.191 0.000
H55-H59 Other disorders of eye and adnexa
0.808 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.807 0.193 0.000
M51.8 Other specified intervertebral disk disorders
0.807 0.193 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.807 0.193 0.000
N64.5 Other signs and symptoms in breast
0.806 0.194 0.000
O04 Medical abortion
0.805 0.195 0.000
M86-M90 Other osteopathies
0.804 0.196 0.000
C53 Malignant neoplasm of cervix uteri
0.804 0.196 0.000
G62 Other polyneuropathies
0.802 0.198 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.800 0.200 0.000
H40 Glaucoma
0.800 0.200 0.000
Chapter I Certain infectious and parasitic diseases
0.799 0.201 0.000
M19.0 Primary arthrosis of other joints
0.798 0.202 0.000
G37 Other demyelinating diseases of central nervous system
0.798 0.202 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.794 0.206 0.000
T39.1 4-Aminophenol derivatives
0.794 0.206 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.789 0.211 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.788 0.212 0.000
C64-C68 Malignant neoplasms of urinary tract
0.787 0.213 0.000
O80-O84 Delivery
0.787 0.213 0.000
H35.4 Peripheral retinal degeneration
0.786 0.214 0.000
C15-C26 Malignant neoplasms of digestive organs
0.784 0.216 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.781 0.219 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.781 0.219 0.000
M25.53 Pain in joint (Forearm)
0.781 0.219 0.000
Z89 Acquired absence of limb
0.777 0.223 0.000
S72 Fracture of femur
0.776 0.224 0.000
M05-M14 Inflammatory polyarthropathies
0.776 0.224 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.775 0.225 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.772 0.228 0.000
Z40 Prophylactic surgery
0.771 0.229 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.770 0.230 0.000
Q50-Q56 Congenital malformations of genital organs
0.769 0.231 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.769 0.231 0.000
H40.1 Primary open-angle glaucoma
0.769 0.231 0.000
T39.0 Salicylates
0.769 0.231 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.767 0.233 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.765 0.235 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.763 0.237 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.762 0.238 0.000
G40 Epilepsy
0.762 0.238 0.000
G63.2 Diabetic polyneuropathy
0.762 0.238 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.761 0.239 0.000
M18 Arthrosis of first carpometacarpal joint
0.761 0.239 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.761 0.239 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.761 0.239 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.760 0.240 0.000
S10-S19 Injuries to the neck
0.759 0.241 0.000
H43 Disorders of vitreous body
0.758 0.242 0.000
H00 Hordeolum and chalazion
0.757 0.243 0.000
O42 Premature rupture of membranes
0.757 0.243 0.000
M19.98 Arthrosis, unspecified (Other)
0.756 0.243 0.000
S82 Fracture of lower leg, including ankle
0.756 0.244 0.000
M19.94 Arthrosis, unspecified (Hand)
0.755 0.245 0.000
M48 Other spondylopathies
0.755 0.245 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.755 0.245 0.000
N60.2 Fibroadenosis of breast
0.754 0.246 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
O03 Spontaneous abortion
0.753 0.246 0.000
T93 Sequelae of injuries of lower limb
0.753 0.247 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.752 0.248 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.752 0.248 0.000
T91 Sequelae of injuries of neck and trunk
0.751 0.249 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.750 0.250 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.747 0.253 0.000
N64.8 Other specified disorders of breast
0.747 0.253 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.746 0.254 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.744 0.256 0.000
H36 Retinal disorders in diseases classified elsewhere
0.744 0.256 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.743 0.257 0.000
M24 Other specific joint derangements
0.742 0.257 0.000
N62 Hypertrophy of breast
0.742 0.258 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.742 0.258 0.000
M50 Cervical disk disorders
0.739 0.261 0.000
S70 Superficial injury of hip and thigh
0.738 0.262 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.736 0.264 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.734 0.266 0.000
M54.9 Dorsalgia, unspecified
0.733 0.267 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.733 0.267 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.731 0.269 0.000
Q00-Q07 Congenital malformations of the nervous system
0.730 0.269 0.000
N60.8 Other benign mammary dysplasias
0.729 0.270 0.000
M31.6 Other giant cell arteritis
0.729 0.271 0.000
M25.46 Effusion of joint (Lower leg)
0.729 0.271 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.729 0.271 0.000
H04 Disorders of lachrymal system
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.727 0.273 0.000
H10 Conjunctivitis
0.727 0.273 0.000
T92 Sequelae of injuries of upper limb
0.726 0.274 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.726 0.274 0.000
F99-F99 Unspecified mental disorder
0.725 0.275 0.000
Q60-Q64 Congenital malformations of the urinary system
0.725 0.275 0.000
F80-F89 Disorders of psychological development
0.725 0.275 0.000
F60-F69 Disorders of adult personality and behaviour
0.724 0.276 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.723 0.277 0.000
N99-N99 Other disorders of the genitourinary system
0.723 0.277 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.718 0.281 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.6 Pain in thoracic spine
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C53.9 Cervix uteri, unspecified
0.717 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M25.59 Pain in joint (Site unspecified)
0.716 0.284 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
M15 Polyarthrosis
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
M21 Other acquired deformities of limbs
0.715 0.285 0.000
G70 Myasthenia gravis and other myoneural disorders
0.714 0.286 0.000
Q80-Q89 Other congenital malformations
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M34 Systemic sclerosis
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.713 0.287 0.000
S72.1 Pertrochanteric fracture
0.713 0.287 0.000
N86 Erosion and ectropion of cervix uteri
0.713 0.287 0.000
G61 Inflammatory polyneuropathy
0.712 0.288 0.000
D05 Carcinoma in situ of breast
0.712 0.288 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.712 0.288 0.000
Z92.8 Personal history of other medical treatment
0.711 0.289 0.000
M16.7 Other secondary coxarthrosis
0.711 0.289 0.000
Z84 Family history of other conditions
0.711 0.289 0.000
Z81 Family history of mental and behavioural disorders
0.711 0.289 0.000
M19.8 Other specified arthrosis
0.710 0.290 0.000
M19.2 Other secondary arthrosis
0.710 0.290 0.000
T90 Sequelae of injuries of head
0.710 0.290 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.709 0.291 0.000
M51.3 Other specified intervertebral disk degeneration
0.709 0.291 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.709 0.291 0.000
M51.9 Intervertebral disk disorder, unspecified
0.709 0.291 0.000
M51.4 Schmorl's nodes
0.709 0.291 0.000
O72 Postpartum haemorrhage
0.709 0.291 0.000
M25.9 Joint disorder, unspecified
0.708 0.292 0.000
M25.8 Other specified joint disorders
0.708 0.292 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.708 0.292 0.000
M25.3 Other instability of joint
0.708 0.292 0.000
M25.2 Flail joint
0.708 0.292 0.000
M25.1 Fistula of joint
0.708 0.292 0.000
M25.0 Haemarthrosis
0.708 0.292 0.000
M19.1 Posttraumatic arthrosis of other joints
0.708 0.292 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.708 0.292 0.000
O85-O92 Complications predominantly related to the puerperium
0.707 0.293 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.707 0.293 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.706 0.294 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.705 0.295 0.000
M54.8 Other dorsalgia
0.705 0.295 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.295 0.000
N73 Other female pelvic inflammatory diseases
0.704 0.296 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.704 0.296 0.000
S81 Open wound of lower leg
0.703 0.297 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.703 0.297 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.702 0.298 0.000
D04 Carcinoma in situ of skin
0.702 0.298 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.701 0.299 0.000
Z83 Family history of other specific disorders
0.701 0.299 0.000
G59.0 Diabetic mononeuropathy
0.700 0.300 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.700 0.300 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.699 0.301 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.699 0.301 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.699 0.301 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.699 0.301 0.000
T36 Poisoning by systemic antibiotics
0.699 0.301 0.000
M54.55 Low back pain (Thoracolumbar region)
0.699 0.301 0.000
M54.54 Low back pain-Thoracic
0.699 0.301 0.000
M54.53 Low back pain-Cervicothoracic
0.699 0.301 0.000
M54.52 Low back pain-Cervical
0.699 0.301 0.000
M54.51 Low back pain-Occipit-atl-axl
0.699 0.301 0.000
M54.50 Low back pain (Multiple sites in spine)
0.699 0.301 0.000
Z85 Personal history of malignant neoplasm
0.698 0.302 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.698 0.302 0.000
M25.57 Pain in joint (Ankle and foot)
0.698 0.302 0.000
O04.9 Complete or unspecified, without complication
0.697 0.303 0.000
M46 Other inflammatory spondylopathies
0.697 0.303 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.696 0.304 0.000
M25.58 Pain in joint (Other)
0.696 0.304 0.000
M25.52 Pain in joint (Upper arm)
0.696 0.304 0.000
C50-C50 Malignant neoplasm of breast
0.695 0.305 0.000
H40.2 Primary angle-closure glaucoma
0.695 0.305 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.695 0.305 0.000
N30-N39 Other diseases of urinary system
0.695 0.305 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.693 0.307 0.000
S20-S29 Injuries to the thorax
0.693 0.307 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.692 0.308 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.692 0.308 0.000
G43 Migraine
0.692 0.308 0.000
H11 Other disorders of conjunctiva
0.692 0.308 0.000
G62.9 Polyneuropathy, unspecified
0.692 0.308 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.690 0.310 0.000
N87 Dysplasia of cervix uteri
0.689 0.311 0.000
N81 Female genital prolapse
0.689 0.311 0.000
Z97.4 Presence of external hearing-aid
0.688 0.312 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.688 0.312 0.000
O40 Polyhydramnios
0.687 0.313 0.000
D80-D89 Certain disorders involving the immune mechanism
0.687 0.313 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.687 0.313 0.000
S40-S49 Injuries to the shoulder and upper arm
0.687 0.313 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.686 0.314 0.000
M80-M85 Disorders of bone density and structure
0.686 0.314 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.685 0.315 0.000
O07 Failed attempted abortion
0.685 0.315 0.000
O06 Unspecified abortion
0.685 0.315 0.000
O05 Other abortion
0.685 0.315 0.000
O01 Hydatidiform mole
0.685 0.315 0.000
O00 Ectopic pregnancy
0.685 0.315 0.000
Z99.3 Dependence on wheelchair
0.685 0.315 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.685 0.315 0.000
S79 Other and unspecified injuries of hip and thigh
0.685 0.315 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.683 0.317 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.682 0.318 0.000
G36 Other acute disseminated demyelination
0.681 0.318 0.000
O73 Retained placenta and membranes, without haemorrhage
0.681 0.319 0.000
S82.8 Fractures of other parts of lower leg
0.681 0.319 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.680 0.319 0.000
M16.5 Other posttraumatic coxarthrosis
0.680 0.319 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.680 0.319 0.000
M16.3 Other dysplastic coxarthrosis
0.680 0.319 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.680 0.319 0.000
H35.7 Separation of retinal layers
0.679 0.321 0.000
H00.1 Chalazion
0.679 0.321 0.000
H35.8 Other specified retinal disorders
0.678 0.321 0.000
N81.2 Incomplete uterovaginal prolapse
0.678 0.322 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.678 0.322 0.000
N11 Chronic tubulo-interstitial nephritis
0.678 0.322 0.000
C18 Malignant neoplasm of colon
0.678 0.322 0.000
O30 Multiple gestation
0.677 0.323 0.000
Z47 Other orthopaedic follow-up care
0.676 0.324 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.676 0.324 0.000
G30-G32 Other degenerative diseases of the nervous system
0.675 0.324 0.000
Z72 Problems related to lifestyle
0.675 0.325 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.674 0.326 0.000
M47 Spondylosis
0.673 0.327 0.000
Z75 Problems related to medical facilities and other health care
0.673 0.327 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.671 0.329 0.000
F70-F79 Mental retardation
0.671 0.329 0.000
G60 Hereditary and idiopathic neuropathy
0.671 0.329 0.000
G64 Other disorders of peripheral nervous system
0.671 0.329 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.669 0.331 0.000
M23.3 Other meniscus derangements
0.668 0.332 0.000
S72.10 Pertrochanteric fracture (closed)
0.668 0.332 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.668 0.332 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.668 0.332 0.000
Q35-Q37 Cleft lip and cleft palate
0.668 0.332 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.668 0.332 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.668 0.332 0.000
Z43 Attention to artificial openings
0.668 0.332 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.668 0.332 0.000
H57 Other disorders of eye and adnexa
0.667 0.333 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.666 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.666 0.334 0.000
H44 Disorders of globe
0.665 0.334 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.665 0.335 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.664 0.336 0.000
H43.1 Vitreous haemorrhage
0.664 0.336 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.663 0.336 0.000
C51 Malignant neoplasm of vulva
0.663 0.336 0.000
C58 Malignant neoplasm of placenta
0.663 0.336 0.000
C52 Malignant neoplasm of vagina
0.663 0.336 0.000
B35-B49 Mycoses
0.663 0.337 0.000
Z52 Donors of organs and tissues
0.662 0.337 0.000
O47 False labour
0.662 0.338 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.662 0.338 0.000
Z92.9 Personal history of medical treatment, unspecified
0.662 0.338 0.000
Z92.5 Personal history of rehabilitation measures
0.662 0.338 0.000
N89 Other noninflammatory disorders of vagina
0.662 0.338 0.000
N64.4 Mastodynia
0.662 0.338 0.000
N64.3 Galactorrhoea not associated with childbirth
0.662 0.338 0.000
N64.2 Atrophy of breast
0.662 0.338 0.000
N64.0 Fissure and fistula of nipple
0.662 0.338 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.662 0.338 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.662 0.338 0.000
Z46 Fitting and adjustment of other devices
0.662 0.338 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.661 0.338 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.661 0.339 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.660 0.340 0.000
H53-H54 Visual disturbances and blindness
0.660 0.340 0.000
M48.0 Spinal stenosis
0.660 0.340 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.660 0.340 0.000
G44 Other headache syndromes
0.657 0.343 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.657 0.343 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.657 0.343 0.000
H31 Other disorders of choroid
0.657 0.343 0.000
H30 Chorioretinal inflammation
0.657 0.343 0.000
T98 Sequelae of other and unspecified effects of external causes
0.656 0.344 0.000
T95 Sequelae of burns, corrosions and frostbite
0.656 0.344 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.656 0.344 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.656 0.344 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.656 0.344 0.000
M25.71 Osteophyte (Shoulder region)
0.656 0.344 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.655 0.345 0.000
S80 Superficial injury of lower leg
0.654 0.346 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.654 0.346 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.654 0.346 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.652 0.348 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.652 0.348 0.000
N60.1 Diffuse cystic mastopathy
0.652 0.348 0.000
T42.4 Benzodiazepines
0.651 0.348 0.000
B25-B34 Other viral diseases
0.651 0.349 0.000
E10-E14 Diabetes mellitus
0.651 0.349 0.000
M06 Other rheumatoid arthritis
0.651 0.349 0.000
G90-G99 Other disorders of the nervous system
0.651 0.349 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.651 0.349 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.651 0.349 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.651 0.349 0.000
T39.4 Antirheumatics, not elsewhere classified
0.651 0.349 0.000
T39.2 Pyrazolone derivatives
0.651 0.349 0.000
H01 Other inflammation of eyelid
0.651 0.349 0.000
H34 Retinal vascular occlusions
0.650 0.349 0.000
D45 Polycythaemia vera
0.650 0.349 0.000
M23.5 Chronic instability of knee
0.650 0.350 0.000
S32 Fracture of lumbar spine and pelvis
0.650 0.350 0.000
M54.1 Radiculopathy
0.650 0.350 0.000
M45 Ankylosing spondylitis
0.649 0.351 0.000
O02.9 Abnormal product of conception, unspecified
0.648 0.352 0.000
O02.8 Other specified abnormal products of conception
0.648 0.352 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.648 0.352 0.000
S78 Traumatic amputation of hip and thigh
0.647 0.353 0.000
S77 Crushing injury of hip and thigh
0.647 0.353 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.647 0.353 0.000
S75 Injury of blood vessels at hip and thigh level
0.647 0.353 0.000
S74 Injury of nerves at hip and thigh level
0.647 0.353 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.647 0.353 0.000
S71 Open wound of hip and thigh
0.647 0.353 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.646 0.354 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.646 0.354 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.645 0.355 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.645 0.355 0.000
N60.9 Benign mammary dysplasia, unspecified
0.644 0.355 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.644 0.356 0.000
M25.51 Pain in joint (Shoulder region)
0.643 0.357 0.000
O82 Single delivery by Caesarean section
0.643 0.357 0.000
Z92.0 Personal history of contraception
0.642 0.358 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.642 0.358 0.000
M40-M43 Deforming dorsopathies
0.641 0.358 0.000
S90 Superficial injury of ankle and foot
0.641 0.359 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.640 0.360 0.000
C21 Malignant neoplasm of anus and anal canal
0.640 0.360 0.000
M25.77 Osteophyte (Ankle and foot)
0.640 0.360 0.000
E11 Non-insulin-dependent diabetes mellitus
0.639 0.361 0.000
Z87.8 Personal history of other specified conditions
0.639 0.361 0.000
M31.3 Wegener's granulomatosis
0.639 0.361 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.639 0.361 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.638 0.362 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.638 0.362 0.000
G57 Mononeuropathies of lower limb
0.637 0.363 0.000
T87 Complications peculiar to reattachment and amputation
0.636 0.364 0.000
M49 Spondylopathies in diseases classified elsewhere
0.636 0.364 0.000
D50-D53 Nutritional anaemias
0.635 0.365 0.000
M25.47 Effusion of joint (Ankle and foot)
0.634 0.366 0.000
Z49 Care involving dialysis
0.633 0.367 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.632 0.367 0.000
N15 Other renal tubulo-interstitial diseases
0.632 0.367 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.632 0.367 0.000
N13 Obstructive and reflux uropathy
0.632 0.368 0.000
H42 Glaucoma in diseases classified elsewhere
0.632 0.368 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.631 0.369 0.000
N20-N23 Urolithiasis
0.631 0.369 0.000
H43.3 Other vitreous opacities
0.631 0.369 0.000
B65-B83 Helminthiases
0.631 0.369 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.630 0.370 0.000
S89 Other and unspecified injuries of lower leg
0.630 0.370 0.000
S88 Traumatic amputation of lower leg
0.630 0.370 0.000
S87 Crushing injury of lower leg
0.630 0.370 0.000
S86 Injury of muscle and tendon at lower leg level
0.630 0.370 0.000
S85 Injury of blood vessels at lower leg level
0.630 0.370 0.000
S84 Injury of nerves at lower leg level
0.630 0.370 0.000
Chapter XX External causes of morbidity and mortality
0.630 0.370 0.000
G70.0 Myasthenia gravis
0.629 0.371 0.000
H10.9 Conjunctivitis, unspecified
0.629 0.371 0.000
F20 Schizophrenia
0.629 0.371 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.628 0.371 0.000
Z94 Transplanted organ and tissue status
0.628 0.372 0.000
M22 Disorders of patella
0.627 0.372 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.627 0.373 0.000
H52 Disorders of refraction and accommodation
0.626 0.374 0.000
H05 Disorders of orbit
0.626 0.374 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.626 0.374 0.000
C20 Malignant neoplasm of rectum
0.626 0.374 0.000
D60-D64 Aplastic and other anaemias
0.625 0.375 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.624 0.376 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.624 0.376 0.000
Z89.4 Acquired absence of foot and ankle
0.623 0.377 0.000
Z72.1 Alcohol use
0.623 0.377 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.623 0.377 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.622 0.377 0.000
M50.1 Cervical disk disorder with radiculopathy
0.622 0.378 0.000
Z54 Convalescence
0.620 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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