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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs192051543
log Bayes Factor = 14.1247
Chromosome 12   position 22,657,770  (GRCh37) Explore rs192051543 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
Z51 Other medical care
0.994 0.006 0.000
Chapter VIII Diseases of the ear and mastoid process
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.985 0.015 0.000
H65-H75 Diseases of middle ear and mastoid
0.981 0.019 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
Z51.5 Palliative care
0.980 0.020 0.000
S80-S89 Injuries to the knee and lower leg
0.978 0.022 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.978 0.022 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
S09 Other and unspecified injuries of head
0.972 0.028 0.000
H72 Perforation of tympanic membrane
0.971 0.029 0.000
E70-E90 Metabolic disorders
0.967 0.033 0.000
E78.5 Hyperlipidaemia, unspecified
0.963 0.037 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.962 0.038 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.959 0.041 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.958 0.042 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.957 0.043 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.957 0.043 0.000
S09.9 Unspecified injury of head
0.954 0.046 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.953 0.047 0.000
M45-M49 Spondylopathies
0.949 0.051 0.000
Z50 Care involving use of rehabilitation procedures
0.948 0.052 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.943 0.057 0.000
Z51.3 Blood transfusion without reported diagnosis
0.940 0.060 0.000
S82 Fracture of lower leg, including ankle
0.935 0.065 0.000
D70 Agranulocytosis
0.932 0.068 0.000
M70-M79 Other soft tissue disorders
0.932 0.068 0.000
S40-S49 Injuries to the shoulder and upper arm
0.931 0.069 0.000
D60-D64 Aplastic and other anaemias
0.927 0.073 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.926 0.074 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.924 0.076 0.000
Z46 Fitting and adjustment of other devices
0.923 0.077 0.000
M47 Spondylosis
0.922 0.078 0.000
E20-E35 Disorders of other endocrine glands
0.919 0.081 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
S01 Open wound of head
0.911 0.089 0.000
C15-C26 Malignant neoplasms of digestive organs
0.909 0.091 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.908 0.092 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.904 0.096 0.000
M47.8 Other spondylosis
0.904 0.096 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.902 0.098 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.899 0.101 0.000
S82.8 Fractures of other parts of lower leg
0.898 0.102 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.898 0.102 0.000
C34 Malignant neoplasm of bronchus and lung
0.897 0.103 0.000
Z48 Other surgical follow-up care
0.893 0.107 0.000
M24 Other specific joint derangements
0.889 0.111 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.884 0.116 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.883 0.117 0.000
M79.6 Pain in limb
0.882 0.118 0.000
D63.0 Anaemia in neoplastic disease
0.877 0.123 0.000
M47.86 Other spondylosis (Lumbar region)
0.877 0.123 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.876 0.124 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.876 0.124 0.000
T90 Sequelae of injuries of head
0.874 0.126 0.000
D45 Polycythaemia vera
0.872 0.128 0.000
C77.0 Lymph nodes of head, face and neck
0.872 0.128 0.000
M60-M63 Disorders of muscles
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.871 0.129 0.000
C73 Malignant neoplasm of thyroid gland
0.870 0.130 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.867 0.133 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.865 0.135 0.000
D69 Purpura and other haemorrhagic conditions
0.865 0.135 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.862 0.138 0.000
S06 Intracranial injury
0.861 0.139 0.000
S80 Superficial injury of lower leg
0.855 0.145 0.000
C77.1 Intrathoracic lymph nodes
0.855 0.145 0.000
H90-H95 Other disorders of ear
0.852 0.148 0.000
Z51.1 Chemotherapy session for neoplasm
0.851 0.149 0.000
Z43 Attention to artificial openings
0.851 0.149 0.000
Z46.6 Fitting and adjustment of urinary device
0.849 0.151 0.000
G40-G47 Episodic and paroxysmal disorders
0.848 0.152 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.846 0.154 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.845 0.155 0.000
Z50.5 Speech therapy
0.844 0.156 0.000
H74 Other disorders of middle ear and mastoid
0.844 0.156 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.842 0.158 0.000
M24.1 Other articular cartilage disorders
0.842 0.158 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.842 0.158 0.000
Chapter I Certain infectious and parasitic diseases
0.841 0.159 0.000
M47.82 Other spondylosis (Cervical region)
0.841 0.159 0.000
S01.8 Open wound of other parts of head
0.838 0.162 0.000
S02 Fracture of skull and facial bones
0.835 0.165 0.000
C77.9 Lymph node, unspecified
0.835 0.165 0.000
S90-S99 Injuries to the ankle and foot
0.833 0.167 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.831 0.169 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.825 0.175 0.000
Z50.8 Care involving use of rehabilitation procedures
0.820 0.180 0.000
H80-H83 Diseases of inner ear
0.818 0.182 0.000
C83.3 Large cell (diffuse)
0.818 0.182 0.000
H72.8 Other perforations of tympanic membrane
0.815 0.185 0.000
C34.1 Upper lobe, bronchus or lung
0.814 0.186 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.813 0.187 0.000
X60-X84 Intentional self-harm
0.813 0.187 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.812 0.188 0.000
Chapter X Diseases of the respiratory system
0.810 0.190 0.000
S05 Injury of eye and orbit
0.808 0.192 0.000
M77 Other enthesopathies
0.808 0.192 0.000
M86-M90 Other osteopathies
0.804 0.196 0.000
C79 Secondary malignant neoplasm of other sites
0.795 0.205 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.794 0.206 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.791 0.209 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.790 0.210 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.788 0.212 0.000
S42 Fracture of shoulder and upper arm
0.788 0.212 0.000
C34.0 Main bronchus
0.787 0.212 0.000
Z48.0 Attention to surgical dressings and sutures
0.787 0.213 0.000
D69.6 Thrombocytopenia, unspecified
0.786 0.214 0.000
T90.5 Sequelae of intracranial injury
0.786 0.214 0.000
G60 Hereditary and idiopathic neuropathy
0.785 0.215 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.785 0.215 0.000
E21.3 Hyperparathyroidism, unspecified
0.784 0.216 0.000
T00-T07 Injuries involving multiple body regions
0.782 0.217 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.782 0.218 0.000
Y00-Y09 Assault
0.781 0.219 0.000
M62 Other disorders of muscle
0.781 0.219 0.000
Z29 Need for other prophylactic measures
0.780 0.220 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.780 0.220 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.780 0.220 0.000
M21 Other acquired deformities of limbs
0.777 0.223 0.000
C77.4 Inguinal and lower limb lymph nodes
0.775 0.225 0.000
G90-G99 Other disorders of the nervous system
0.775 0.225 0.000
Y43 Primarily systemic agents
0.775 0.225 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.774 0.226 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.772 0.228 0.000
Z43.3 Attention to colostomy
0.772 0.228 0.000
S80.9 Superficial injury of lower leg, unspecified
0.772 0.228 0.000
Z50.2 Alcohol rehabilitation
0.772 0.228 0.000
S01.5 Open wound of lip and oral cavity
0.771 0.229 0.000
Z47 Other orthopaedic follow-up care
0.770 0.230 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.770 0.230 0.000
G62 Other polyneuropathies
0.769 0.231 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.769 0.231 0.000
S82.2 Fracture of shaft of tibia
0.768 0.232 0.000
S40 Superficial injury of shoulder and upper arm
0.765 0.235 0.000
S32 Fracture of lumbar spine and pelvis
0.765 0.235 0.000
Z50.1 Other physical therapy
0.764 0.236 0.000
C88 Malignant immunoproliferative diseases
0.764 0.236 0.000
D47.4 Osteomyelofibrosis
0.763 0.237 0.000
M91-M94 Chondropathies
0.763 0.237 0.000
D80-D89 Certain disorders involving the immune mechanism
0.763 0.237 0.000
S82.6 Fracture of lateral malleolus
0.763 0.237 0.000
E83 Disorders of mineral metabolism
0.762 0.238 0.000
V40-V49 Car occupant injured in transport accident
0.760 0.240 0.000
D47.1 Chronic myeloproliferative disease
0.760 0.240 0.000
M79.7 Fibromyalgia
0.758 0.242 0.000
S81 Open wound of lower leg
0.758 0.242 0.000
E21.0 Primary hyperparathyroidism
0.757 0.242 0.000
M84 Disorders of continuity of bone
0.757 0.242 0.000
M80 Osteoporosis with pathological fracture
0.757 0.243 0.000
T92 Sequelae of injuries of upper limb
0.757 0.243 0.000
C77.5 Intrapelvic lymph nodes
0.755 0.245 0.000
E89.0 Postprocedural hypothyroidism
0.754 0.246 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.753 0.247 0.000
E87.6 Hypokalaemia
0.753 0.247 0.000
E22 Hyperfunction of pituitary gland
0.752 0.248 0.000
G30-G32 Other degenerative diseases of the nervous system
0.752 0.248 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.750 0.250 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.750 0.250 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.750 0.250 0.000
H71 Cholesteatoma of middle ear
0.750 0.250 0.000
S20-S29 Injuries to the thorax
0.749 0.251 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.749 0.251 0.000
Z49 Care involving dialysis
0.749 0.251 0.000
Z54 Convalescence
0.748 0.251 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.747 0.253 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.746 0.254 0.000
A00-A09 Intestinal infectious diseases
0.745 0.255 0.000
C15 Malignant neoplasm of oesophagus
0.745 0.255 0.000
E50-E64 Other nutritional deficiencies
0.743 0.257 0.000
H73 Other disorders of tympanic membrane
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
M22 Disorders of patella
0.742 0.258 0.000
T93 Sequelae of injuries of lower limb
0.742 0.258 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.742 0.258 0.000
D72 Other disorders of white blood cells
0.742 0.258 0.000
Y86 Sequelae of other accidents
0.741 0.258 0.000
Z44 Fitting and adjustment of external prosthetic device
0.741 0.259 0.000
Y84.6 Urinary catheterisation
0.740 0.260 0.000
H74.0 Tympanosclerosis
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.738 0.262 0.000
H69 Other disorders of Eustachian tube
0.738 0.262 0.000
S70-S79 Injuries to the hip and thigh
0.738 0.262 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
S01.4 Open wound of cheek and temporomandibular area
0.735 0.265 0.000
M79.62 Pain in limb (Upper arm)
0.735 0.265 0.000
C64-C68 Malignant neoplasms of urinary tract
0.735 0.265 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.735 0.265 0.000
D46 Myelodysplastic syndromes
0.734 0.265 0.000
Z48.9 Surgical follow-up care, unspecified
0.733 0.267 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.730 0.270 0.000
G70-G73 Diseases of myoneural junction and muscle
0.729 0.270 0.000
T98 Sequelae of other and unspecified effects of external causes
0.728 0.272 0.000
C81 Hodgkin's disease
0.727 0.273 0.000
S60-S69 Injuries to the wrist and hand
0.727 0.273 0.000
M79.60 Pain in limb (Multiple sites)
0.725 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.725 0.275 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.725 0.275 0.000
W20-W49 Exposure to inanimate mechanical forces
0.724 0.276 0.000
Q60-Q64 Congenital malformations of the urinary system
0.724 0.276 0.000
Q80-Q89 Other congenital malformations
0.722 0.278 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.721 0.279 0.000
M79.64 Pain in limb (Hand)
0.721 0.279 0.000
Z45 Adjustment and management of implanted device
0.720 0.280 0.000
S41 Open wound of shoulder and upper arm
0.719 0.280 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.719 0.281 0.000
T90.9 Sequelae of unspecified injury of head
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M62.8 Other specified disorders of muscle
0.717 0.283 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
S01.7 Multiple open wounds of head
0.716 0.284 0.000
Q00-Q07 Congenital malformations of the nervous system
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.715 0.285 0.000
S07 Crushing injury of head
0.715 0.285 0.000
S04 Injury of cranial nerves
0.715 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
S82.81 Fractures of other parts of lower leg (open)
0.715 0.285 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
Z51.9 Medical care, unspecified
0.712 0.287 0.000
Z51.6 Desensitisation to allergens
0.712 0.287 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.712 0.287 0.000
D68 Other coagulation defects
0.712 0.288 0.000
M24.2 Disorder of ligament
0.711 0.289 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.711 0.289 0.000
G43 Migraine
0.710 0.290 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.709 0.291 0.000
C25 Malignant neoplasm of pancreas
0.709 0.291 0.000
J80 Adult respiratory distress syndrome
0.709 0.291 0.000
S02.2 Fracture of nasal bones
0.709 0.291 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.709 0.291 0.000
G62.9 Polyneuropathy, unspecified
0.708 0.292 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.708 0.292 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.707 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
H92 Otalgia and effusion of ear
0.707 0.293 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.706 0.293 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.706 0.293 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.706 0.293 0.000
Z29.2 Other prophylactic chemotherapy
0.706 0.294 0.000
J81 Pulmonary oedema
0.706 0.294 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.706 0.294 0.000
T91 Sequelae of injuries of neck and trunk
0.705 0.295 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.704 0.296 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.704 0.296 0.000
C32 Malignant neoplasm of larynx
0.704 0.296 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.703 0.296 0.000
H70 Mastoiditis and related conditions
0.703 0.296 0.000
H68 Eustachian salpingitis and obstruction
0.703 0.296 0.000
H67 Otitis media in diseases classified elsewhere
0.703 0.296 0.000
S82.3 Fracture of lower end of tibia
0.703 0.297 0.000
G83 Other paralytic syndromes
0.703 0.297 0.000
Y85 Sequelae of transport accidents
0.702 0.298 0.000
S88 Traumatic amputation of lower leg
0.701 0.298 0.000
S87 Crushing injury of lower leg
0.701 0.298 0.000
S86 Injury of muscle and tendon at lower leg level
0.701 0.298 0.000
S85 Injury of blood vessels at lower leg level
0.701 0.298 0.000
S84 Injury of nerves at lower leg level
0.701 0.298 0.000
H91 Other hearing loss
0.701 0.299 0.000
E27 Other disorders of adrenal gland
0.701 0.299 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.701 0.299 0.000
G60.0 Hereditary motor and sensory neuropathy
0.700 0.299 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.700 0.300 0.000
E24 Cushing's syndrome
0.700 0.300 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.699 0.301 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.699 0.301 0.000
S09.8 Other specified injuries of head
0.697 0.303 0.000
S09.7 Multiple injuries of head
0.697 0.303 0.000
S09.2 Traumatic rupture of ear drum
0.697 0.303 0.000
S09.1 Injury of muscle and tendon of head
0.697 0.303 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.697 0.303 0.000
Z86 Personal history of certain other diseases
0.696 0.304 0.000
H72.2 Other marginal perforations of tympanic membrane
0.696 0.304 0.000
H72.1 Attic perforation of tympanic membrane
0.696 0.304 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.695 0.305 0.000
S91 Open wound of ankle and foot
0.695 0.305 0.000
M79.67 Pain in limb (Ankle and foot)
0.695 0.305 0.000
M77.1 Lateral epicondylitis
0.694 0.306 0.000
E85 Amyloidosis
0.693 0.306 0.000
E84 Cystic fibrosis
0.693 0.306 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.306 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.306 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.306 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.306 0.000
E74 Other disorders of carbohydrate metabolism
0.693 0.306 0.000
E73 Lactose intolerance
0.693 0.306 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.306 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.306 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.306 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.306 0.000
H81 Disorders of vestibular function
0.693 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.692 0.308 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.692 0.308 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.691 0.309 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.691 0.309 0.000
Z46.8 Fitting and adjustment of other specified devices
0.691 0.309 0.000
S42.2 Fracture of upper end of humerus
0.690 0.310 0.000
M79.63 Pain in limb (Forearm)
0.690 0.310 0.000
E78.8 Other disorders of lipoprotein metabolism
0.689 0.310 0.000
E78.6 Lipoprotein deficiency
0.689 0.310 0.000
E78.4 Other hyperlipidaemia
0.689 0.310 0.000
E78.3 Hyperchylomicronaemia
0.689 0.310 0.000
E78.2 Mixed hyperlipidaemia
0.689 0.310 0.000
E78.1 Pure hyperglyceridaemia
0.689 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.688 0.312 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.688 0.312 0.000
C34.9 Bronchus or lung, unspecified
0.687 0.313 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.687 0.313 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.687 0.313 0.000
Z22 Carrier of infectious disease
0.687 0.313 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.686 0.314 0.000
C95 Leukaemia of unspecified cell type
0.686 0.314 0.000
C94 Other leukaemias of specified cell type
0.686 0.314 0.000
C93 Monocytic leukaemia
0.686 0.314 0.000
C86 Other specified types of T/NK-cell lymphoma
0.686 0.314 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.686 0.314 0.000
D74 Methaemoglobinaemia
0.686 0.314 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.686 0.314 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.686 0.314 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.685 0.315 0.000
E87.7 Fluid overload
0.683 0.317 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.683 0.317 0.000
T95 Sequelae of burns, corrosions and frostbite
0.683 0.317 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.683 0.317 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.683 0.317 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.683 0.317 0.000
S01.3 Open wound of ear
0.682 0.318 0.000
G61 Inflammatory polyneuropathy
0.682 0.318 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.681 0.319 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.681 0.319 0.000
M49 Spondylopathies in diseases classified elsewhere
0.681 0.319 0.000
M45 Ankylosing spondylitis
0.680 0.320 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.680 0.320 0.000
Z50.6 Orthoptic training
0.679 0.320 0.000
Z50.3 Drug rehabilitation
0.679 0.320 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.679 0.321 0.000
M46 Other inflammatory spondylopathies
0.679 0.321 0.000
G41 Status epilepticus
0.679 0.321 0.000
S82.4 Fracture of fibula alone
0.679 0.321 0.000
M35 Other systemic involvement of connective tissue
0.679 0.321 0.000
C77.2 Intra-abdominal lymph nodes
0.678 0.322 0.000
M79.2 Neuralgia and neuritis, unspecified
0.676 0.324 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.676 0.324 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.676 0.324 0.000
C31 Malignant neoplasm of accessory sinuses
0.676 0.324 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.676 0.324 0.000
C37 Malignant neoplasm of thymus
0.676 0.324 0.000
C33 Malignant neoplasm of trachea
0.676 0.324 0.000
M79.69 Pain in limb (Site unspecified)
0.676 0.324 0.000
Y57 Other and unspecified drugs and medicaments
0.674 0.326 0.000
M25 Other joint disorders, not elsewhere classified
0.673 0.327 0.000
S89 Other and unspecified injuries of lower leg
0.673 0.327 0.000
S00 Superficial injury of head
0.673 0.327 0.000
C21 Malignant neoplasm of anus and anal canal
0.671 0.329 0.000
Z40 Prophylactic surgery
0.671 0.329 0.000
C77.8 Lymph nodes of multiple regions
0.670 0.329 0.000
S82.9 Fracture of lower leg, part unspecified
0.670 0.330 0.000
S82.7 Multiple fractures of lower leg
0.670 0.330 0.000
D41.0 Kidney
0.670 0.330 0.000
M79.66 Pain in limb (Lower leg)
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.669 0.331 0.000
H60-H62 Diseases of external ear
0.668 0.332 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.668 0.332 0.000
D41.4 Bladder
0.668 0.332 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.668 0.332 0.000
D61 Other aplastic anaemias
0.668 0.332 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.668 0.332 0.000
C34.2 Middle lobe, bronchus or lung
0.667 0.332 0.000
M65-M68 Disorders of synovium and tendon
0.667 0.333 0.000
S48 Traumatic amputation of shoulder and upper arm
0.667 0.333 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.667 0.333 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.667 0.333 0.000
S44 Injury of nerves at shoulder and upper arm level
0.667 0.333 0.000
S47 Crushing injury of shoulder and upper arm
0.667 0.333 0.000
Y88 Sequelae of surgical and medical care as external cause
0.667 0.333 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.666 0.334 0.000
S06.2 Diffuse brain injury
0.666 0.334 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.665 0.335 0.000
J60-J70 Lung diseases due to external agents
0.664 0.336 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.664 0.336 0.000
D67 Hereditary factor IX deficiency
0.664 0.336 0.000
D66 Hereditary factor VIII deficiency
0.664 0.336 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.664 0.336 0.000
M24.0 Loose body in joint
0.663 0.336 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.663 0.337 0.000
C74 Malignant neoplasm of adrenal gland
0.663 0.337 0.000
M47.1 Other spondylosis with myelopathy
0.662 0.338 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.662 0.338 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.662 0.338 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.662 0.338 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.662 0.338 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.662 0.338 0.000
Z46.1 Fitting and adjustment of hearing aid
0.662 0.338 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.662 0.338 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.662 0.338 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.661 0.339 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.661 0.339 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.661 0.339 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.660 0.340 0.000
S01.0 Open wound of scalp
0.660 0.340 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.659 0.341 0.000
E34 Other endocrine disorders
0.659 0.341 0.000
E32 Diseases of thymus
0.659 0.341 0.000
E31 Polyglandular dysfunction
0.659 0.341 0.000
E30 Disorders of puberty, not elsewhere classified
0.659 0.341 0.000
E29 Testicular dysfunction
0.659 0.341 0.000
E26 Hyperaldosteronism
0.659 0.341 0.000
E25 Adrenogenital disorders
0.659 0.341 0.000
E20 Hypoparathyroidism
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.659 0.341 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.659 0.341 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.658 0.342 0.000
S06.4 Epidural haemorrhage
0.658 0.342 0.000
H72.0 Central perforation of tympanic membrane
0.658 0.342 0.000
C16 Malignant neoplasm of stomach
0.657 0.343 0.000
M47.9 Spondylosis, unspecified
0.657 0.343 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.657 0.343 0.000
S06.8 Other intracranial injuries
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.656 0.344 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.656 0.344 0.000
M79.79 Fibromyalgia (Site unspecified)
0.655 0.345 0.000
E40-E46 Malnutrition
0.655 0.345 0.000
J40-J47 Chronic lower respiratory diseases
0.654 0.346 0.000
S05.9 Injury of eye and orbit, part unspecified
0.654 0.346 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.653 0.347 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.652 0.348 0.000
C17 Malignant neoplasm of small intestine
0.652 0.348 0.000
C23 Malignant neoplasm of gallbladder
0.652 0.348 0.000
D40.0 Prostate
0.652 0.348 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.651 0.349 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.651 0.349 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.651 0.349 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.651 0.349 0.000
C22.0 Liver cell carcinoma
0.651 0.349 0.000
B25-B34 Other viral diseases
0.651 0.349 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.649 0.351 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.648 0.352 0.000
Q50-Q56 Congenital malformations of genital organs
0.648 0.352 0.000
Q35-Q37 Cleft lip and cleft palate
0.648 0.352 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.648 0.352 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.648 0.352 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.648 0.352 0.000
M47.84 Other spondylosis (Thoracic region)
0.648 0.352 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.648 0.352 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.648 0.352 0.000
G64 Other disorders of peripheral nervous system
0.648 0.352 0.000
D64 Other anaemias
0.647 0.353 0.000
M79.9 Soft tissue disorder, unspecified
0.646 0.353 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.646 0.353 0.000
M79.3 Panniculitis, unspecified
0.646 0.353 0.000
M79.1 Myalgia
0.646 0.353 0.000
M89 Other disorders of bone
0.646 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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