TreeWAS – Variant ID: rs1975197

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z22.3 Carrier of other specified bacterial diseases	0.000	0.956	0.044
D73.0 Hyposplenism	0.000	0.976	0.024
D72.8 Other specified disorders of white blood cells	0.000	0.977	0.023
D72 Other disorders of white blood cells	0.000	0.979	0.021
D73 Diseases of spleen	0.000	0.979	0.021
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.980	0.020
D70 Agranulocytosis	0.000	0.981	0.019
Z22 Carrier of infectious disease	0.000	0.982	0.018
D72.9 Disorder of white blood cells, unspecified	0.000	0.985	0.015
D72.0 Genetic anomalies of leukocytes	0.000	0.985	0.015
D72.1 Eosinophilia	0.000	0.985	0.015
D73.9 Disease of spleen, unspecified	0.000	0.985	0.015
D73.3 Abscess of spleen	0.000	0.985	0.015
D73.2 Chronic congestive splenomegaly	0.000	0.985	0.015
D73.5 Infarction of spleen	0.000	0.985	0.015
D74 Methaemoglobinaemia	0.000	0.985	0.014
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.985	0.014
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.985	0.014
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.986	0.014
D73.8 Other diseases of spleen	0.000	0.986	0.014
D73.4 Cyst of spleen	0.000	0.986	0.014
D73.1 Hypersplenism	0.000	0.987	0.013
Z22.5 Carrier of viral hepatitis	0.000	0.987	0.013
Z22.9 Carrier of infectious disease, unspecified	0.000	0.987	0.013
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.987	0.013
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.987	0.013
Z22.2 Carrier of diphtheria	0.000	0.987	0.013
Z22.0 Carrier of typhoid	0.000	0.987	0.013
Z22.8 Carrier of other infectious diseases	0.000	0.987	0.013
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.989	0.011
D74.9 Methaemoglobinaemia, unspecified	0.000	0.989	0.010
D74.8 Other methaemoglobinaemias	0.000	0.989	0.010
D74.0 Congenital methaemoglobinaemia	0.000	0.989	0.010
D14.0 Middle ear, nasal cavity and accessory sinuses	0.010	0.990	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.990	0.010
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.990	0.010
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.990	0.010
S91.1 Open wound of toe(s) without damage to nail	0.010	0.990	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.990	0.010
D76.3 Other histiocytosis syndromes	0.000	0.990	0.010
S91.3 Open wound of other parts of foot	0.010	0.990	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.990	0.010
S91 Open wound of ankle and foot	0.009	0.990	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.000	0.991	0.009
S91.0 Open wound of ankle	0.008	0.992	0.000
Q38.7 Pharyngeal pouch	0.000	0.992	0.008
E53.8 Deficiency of other specified B group vitamins	0.008	0.992	0.000
K01.1 Impacted teeth	0.000	0.993	0.007
D75.0 Familial erythrocytosis	0.000	0.993	0.007
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.993	0.007
D75.2 Essential thrombocytosis	0.000	0.993	0.007
S91.7 Multiple open wounds of ankle and foot	0.007	0.993	0.000
S91.2 Open wound of toe(s) with damage to nail	0.007	0.993	0.000
R80 Isolated proteinuria	0.000	0.994	0.006
D14 Benign neoplasm of middle ear and respiratory system	0.006	0.994	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.006	0.994	0.000
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
E53.9 Vitamin B deficiency, unspecified	0.006	0.994	0.000
R22.1 Localised swelling, mass and lump, neck	0.006	0.994	0.000
D14.3 Bronchus and lung	0.006	0.994	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.006	0.994	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.006	0.994	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.994	0.006
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.995	0.005
I72.4 Aneurysm of artery of lower extremity	0.000	0.995	0.005
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
D14.1 Larynx	0.005	0.995	0.000
D14.4 Respiratory system, unspecified	0.005	0.995	0.000
D14.2 Trachea	0.005	0.995	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.995	0.005
G25.8 Other specified extrapyramidal and movement disorders	0.005	0.995	0.000
K50.0 Crohn's disease of small intestine	0.000	0.995	0.005
E53.1 Pyridoxine deficiency	0.004	0.995	0.000
E53.0 Riboflavin deficiency	0.004	0.995	0.000
S02 Fracture of skull and facial bones	0.000	0.996	0.004
S02.50 Fracture of tooth (closed)	0.000	0.996	0.004
I72 Other aneurysm	0.000	0.996	0.004
S02.60 Fracture of mandible (closed)	0.000	0.996	0.004
S02.6 Fracture of mandible	0.000	0.996	0.004
S02.5 Fracture of tooth	0.000	0.996	0.004
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.996	0.004
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.996	0.003
I72.0 Aneurysm of carotid artery	0.000	0.996	0.004
Z28 Immunisation not carried out	0.000	0.996	0.004
Z27 Need for immunisation against combinations of infectious diseases	0.000	0.996	0.004
Z26 Need for immunisation against other single infectious diseases	0.000	0.996	0.004
Z25 Need for immunisation against other single viral diseases	0.000	0.996	0.004
Z24 Need for immunisation against certain single viral diseases	0.000	0.996	0.004
Z23 Need for immunisation against single bacterial diseases	0.000	0.996	0.004
Z20 Contact with and exposure to communicable diseases	0.000	0.996	0.004
I72.8 Aneurysm of other specified arteries	0.000	0.996	0.004
Q38 Other congenital malformations of tongue, mouth and pharynx	0.000	0.996	0.004
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.996	0.004
Z98.2 Presence of cerebrospinal fluid drainage device	0.004	0.996	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.996	0.004
S02.8 Fractures of other skull and facial bones	0.000	0.996	0.004
S02.1 Fracture of base of skull	0.000	0.996	0.004
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.004	0.996	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.996	0.003
I51.9 Heart disease, unspecified	0.000	0.996	0.004
N92.0 Excessive and frequent menstruation with regular cycle	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
I72.2 Aneurysm of renal artery	0.000	0.997	0.003
I72.9 Aneurysm of unspecified site	0.000	0.997	0.003
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
S02.0 Fracture of vault of skull	0.000	0.997	0.003
S02.51 Fracture of tooth (open)	0.000	0.997	0.003
S02.61 Fracture of mandible (open)	0.000	0.997	0.003
K62.9 Disease of anus and rectum, unspecified	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.997	0.003
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.003	0.997	0.000
M45 Ankylosing spondylitis	0.003	0.997	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.000	0.997	0.003
Z20.8 Contact with and exposure to other communicable diseases	0.000	0.997	0.003
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.000	0.997	0.003
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.000	0.997	0.003
Z20.5 Contact with and exposure to viral hepatitis	0.000	0.997	0.003
Z20.4 Contact with and exposure to rubella	0.000	0.997	0.003
Z20.3 Contact with and exposure to rabies	0.000	0.997	0.003
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.000	0.997	0.003
Z20.1 Contact with and exposure to tuberculosis	0.000	0.997	0.003
Z20.0 Contact with and exposure to intestinal infectious diseases	0.000	0.997	0.003
Z23.8 Need for immunisation against other single bacterial diseases	0.000	0.997	0.003
Z23.7 Need for immunisation against pertussis alone	0.000	0.997	0.003
Z23.6 Need for immunisation against diphtheria alone	0.000	0.997	0.003
Z23.5 Need for immunisation against tetanus alone	0.000	0.997	0.003
Z23.4 Need for immunisation against tularaemia	0.000	0.997	0.003
Z23.3 Need for immunisation against plague	0.000	0.997	0.003
Z23.2 Need for immunisation against tuberculosis [BCG]	0.000	0.997	0.003
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.000	0.997	0.003
Z23.0 Need for immunisation against cholera alone	0.000	0.997	0.003
Z24.6 Need for immunisation against viral hepatitis	0.000	0.997	0.003
Z24.5 Need for immunisation against rubella alone	0.000	0.997	0.003
Z24.4 Need for immunisation against measles alone	0.000	0.997	0.003
Z24.3 Need for immunisation against yellow fever	0.000	0.997	0.003
Z24.2 Need for immunisation against rabies	0.000	0.997	0.003
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.000	0.997	0.003
Z24.0 Need for immunisation against poliomyelitis	0.000	0.997	0.003
Z25.8 Need for immunisation against other specified single viral diseases	0.000	0.997	0.003
Z25.1 Need for immunisation against influenza	0.000	0.997	0.003
Z25.0 Need for immunisation against mumps alone	0.000	0.997	0.003
Z26.9 Need for immunisation against unspecified infectious disease	0.000	0.997	0.003
Z26.8 Need for immunisation against other specified single infectious diseases	0.000	0.997	0.003
Z26.0 Need for immunisation against leishmaniasis	0.000	0.997	0.003
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.000	0.997	0.003
Z27.8 Need for immunisation against other combinations of infectious diseases	0.000	0.997	0.003
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.000	0.997	0.003
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.000	0.997	0.003
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.000	0.997	0.003
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.000	0.997	0.003
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.000	0.997	0.003
Z28.9 Immunisation not carried out for unspecified reason	0.000	0.997	0.003
Z28.8 Immunisation not carried out for other reasons	0.000	0.997	0.003
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.000	0.997	0.003
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.000	0.997	0.003
Z28.0 Immunisation not carried out because of contraindication	0.000	0.997	0.003
E83.5 Disorders of calcium metabolism	0.000	0.997	0.003
Q38.8 Other congenital malformations of pharynx	0.000	0.997	0.003
Q38.6 Other congenital malformations of mouth	0.000	0.997	0.003
Q38.5 Congenital malformations of palate, not elsewhere classified	0.000	0.997	0.003
Q38.4 Congenital malformations of salivary glands and ducts	0.000	0.997	0.003
Q38.3 Other congenital malformations of tongue	0.000	0.997	0.003
Q38.2 Macroglossia	0.000	0.997	0.003
Q38.0 Congenital malformations of lips, not elsewhere classified	0.000	0.997	0.003
S51.9 Open wound of forearm, part unspecified	0.000	0.997	0.003
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.997	0.003
S02.81 Fractures of other skull and facial bones (open)	0.000	0.997	0.003
S02.11 Fracture of base of skull (open)	0.000	0.997	0.003
I72.3 Aneurysm of iliac artery	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.003	0.997	0.000
N99.5 Malfunction of external stoma of urinary tract	0.003	0.997	0.000
Z03.4 Observation for suspected myocardial infarction	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.001	0.997	0.002
N99.2 Postprocedural adhesions of vagina	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.000	0.997	0.003
N99.0 Postprocedural renal failure	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.000	0.997	0.003
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.003	0.997	0.000
N99.1 Postprocedural urethral stricture	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.000	0.997	0.002
S02.01 Fracture of vault of skull (open)	0.000	0.997	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.997	0.002
S92.0 Fracture of calcaneus	0.003	0.997	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.002	0.997	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.002	0.997	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.002	0.997	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.002	0.997	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.002	0.997	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.002	0.997	0.000
K01 Embedded and impacted teeth	0.000	0.997	0.003
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.002
I60 Subarachnoid haemorrhage	0.003	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.997	0.002
S51.0 Open wound of elbow	0.000	0.997	0.003
S99.8 Other specified injuries of ankle and foot	0.002	0.997	0.000
S92.3 Fracture of metatarsal bone	0.002	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
S92.1 Fracture of talus	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
S51 Open wound of forearm	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.998	0.002
E83.4 Disorders of magnesium metabolism	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
S06 Intracranial injury	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
R10.0 Acute abdomen	0.000	0.998	0.002
S81.0 Open wound of knee	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.000	0.998	0.002
E51 Thiamine deficiency	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
K01.0 Embedded teeth	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
E54 Ascorbic acid deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
D43.2 Brain, unspecified	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
I60.8 Other subarachnoid haemorrhage	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
R22.9 Localised swelling, mass and lump, unspecified	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.001	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
Q42 Congenital absence, atresia and stenosis of large intestine	0.000	0.998	0.001
Q41 Congenital absence, atresia and stenosis of small intestine	0.000	0.998	0.001
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.001	0.998	0.000
E56.8 Deficiency of other vitamins	0.001	0.998	0.000
E56.0 Deficiency of vitamin E	0.001	0.998	0.000
I35.1 Aortic (valve) insufficiency	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.998	0.002
Q45 Other congenital malformations of digestive system	0.000	0.998	0.001
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
G24.5 Blepharospasm	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.001	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.998	0.001
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.001	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
I78 Diseases of capillaries	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.000	0.998	0.001
N99-N99 Other disorders of the genitourinary system	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
E51.9 Thiamine deficiency, unspecified	0.001	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.001	0.998	0.000
E51.1 Beriberi	0.001	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.001	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.001	0.998	0.000
G25.5 Other chorea	0.001	0.998	0.000
G25.4 Drug-induced chorea	0.001	0.998	0.000
G95.2 Cord compression, unspecified	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.000	0.998	0.001
Q43.6 Congenital fistula of rectum and anus	0.000	0.998	0.001
Q43.5 Ectopic anus	0.000	0.998	0.001
Q43.4 Duplication of intestine	0.000	0.998	0.001
Q43.2 Other congenital functional disorders of colon	0.000	0.998	0.001
Q43.1 Hirschsprung's disease	0.000	0.998	0.001
Q43.0 Meckel's diverticulum	0.000	0.998	0.001
S51.7 Multiple open wounds of forearm	0.000	0.998	0.001
S70.0 Contusion of hip	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.001
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.998	0.000
N21 Calculus of lower urinary tract	0.002	0.998	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.998	0.002
I78.8 Other diseases of capillaries	0.000	0.998	0.001
S06.9 Intracranial injury, unspecified	0.000	0.998	0.001
S06.3 Focal brain injury	0.000	0.998	0.001
Z45.0 Adjustment and management of cardiac pacemaker	0.002	0.998	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.001
G24.3 Spasmodic torticollis	0.001	0.998	0.000
N21.8 Other lower urinary tract calculus	0.001	0.998	0.000
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.000	0.998	0.001
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
C32.0 Glottis	0.000	0.998	0.001
E50.9 Vitamin A deficiency, unspecified	0.001	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.001	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.001	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.001	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.001	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.001	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.001	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.001	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.001	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.001	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.001	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.001	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.001	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.001	0.998	0.000
E64.3 Sequelae of rickets	0.001	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.001	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.001	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.001	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.000	0.998	0.001
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.001	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.001	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.998	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.001	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.001	0.998	0.001
S92.50 Fracture of other toe (closed)	0.001	0.998	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
S06.0 Concussion	0.000	0.998	0.001
Z43.2 Attention to ileostomy	0.001	0.998	0.000
I74 Arterial embolism and thrombosis	0.000	0.998	0.001
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.999	0.001
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.999	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.999	0.001
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.999	0.001
S82.21 Fracture of shaft of tibia (open)	0.001	0.999	0.000
D33.3 Cranial nerves	0.001	0.999	0.000
G24.8 Other dystonia	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.999	0.001
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.999	0.001
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.000	0.999	0.001
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.000	0.999	0.001
Q41.2 Congenital absence, atresia and stenosis of ileum	0.000	0.999	0.001
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.000	0.999	0.001
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.000	0.999	0.001
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.000	0.999	0.001
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.000	0.999	0.001
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.000	0.999	0.001
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.000	0.999	0.001
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.000	0.999	0.001
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.000	0.999	0.001
G37 Other demyelinating diseases of central nervous system	0.000	0.999	0.001
C16.3 Pyloric antrum	0.001	0.999	0.000
F31.8 Other bipolar affective disorders	0.000	0.999	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001
Q45.9 Congenital malformation of digestive system, unspecified	0.000	0.999	0.001
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.000	0.999	0.001
Q45.2 Congenital pancreatic cyst	0.000	0.999	0.001
Q45.1 Annular pancreas	0.000	0.999	0.001
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.000	0.999	0.001
G24 Dystonia	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
G25.2 Other specified forms of tremor	0.001	0.999	0.000
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
Q44.7 Other congenital malformations of liver	0.000	0.999	0.001
Q44.5 Other congenital malformations of bile ducts	0.000	0.999	0.001
Q44.4 Choledochal cyst	0.000	0.999	0.001
Q44.3 Congenital stenosis and stricture of bile ducts	0.000	0.999	0.001
Q44.2 Atresia of bile ducts	0.000	0.999	0.001
Q44.1 Other congenital malformations of gallbladder	0.000	0.999	0.001
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.000	0.999	0.001
E55 Vitamin D deficiency	0.001	0.999	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
C16.5 Lesser curvature of stomach, unspecified	0.001	0.999	0.000
C25.9 Pancreas, unspecified	0.001	0.999	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.999	0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.999	0.001
I78.9 Disease of capillaries, unspecified	0.000	0.999	0.001
Q39.9 Congenital malformation of oesophagus, unspecified	0.000	0.999	0.001
Q39.8 Other congenital malformations of oesophagus	0.000	0.999	0.001
Q39.6 Diverticulum of oesophagus	0.000	0.999	0.001
Q39.5 Congenital dilatation of oesophagus	0.000	0.999	0.001
Q39.3 Congenital stenosis and stricture of oesophagus	0.000	0.999	0.001
Q39.2 Congenital tracheooesophageal fistula without atresia	0.000	0.999	0.001
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.000	0.999	0.001
Q39.0 Atresia of oesophagus without fistula	0.000	0.999	0.001
Q45.8 Other specified congenital malformations of digestive system	0.000	0.999	0.001
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.999	0.001
K27 Peptic ulcer, site unspecified	0.001	0.999	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.999	0.001
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.999	0.001
N21.9 Calculus of lower urinary tract, unspecified	0.001	0.999	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.999	0.001
E61 Deficiency of other nutrient elements	0.001	0.999	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.001	0.999	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.999	0.001
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
C25.2 Tail of pancreas	0.001	0.999	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.999	0.001
S52.20 Fracture of shaft of ulna (closed)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations