TreeWAS – Variant ID: rs198817

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
K90 Intestinal malabsorption	0.472	0.528	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.413	0.587	0.000
K90.3 Pancreatic steatorrhoea	0.338	0.662	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.338	0.662	0.000
K90.1 Tropical sprue	0.338	0.662	0.000
K90.8 Other intestinal malabsorption	0.319	0.681	0.000
K90.9 Intestinal malabsorption, unspecified	0.243	0.757	0.000
E83 Disorders of mineral metabolism	0.000	0.942	0.058
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.955	0.045
E83.8 Other disorders of mineral metabolism	0.000	0.958	0.042
E83.2 Disorders of zinc metabolism	0.000	0.958	0.042
E83.0 Disorders of copper metabolism	0.000	0.958	0.042
K90-K93 Other diseases of the digestive system	0.040	0.960	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.967	0.033
K93 Disorders of other digestive organs in diseases classified elsewhere	0.029	0.971	0.000
D27 Benign neoplasm of ovary	0.023	0.977	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.021	0.979	0.000
K93.1 Megacolon in Chagas' disease	0.021	0.979	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.021	0.979	0.000
E05.9 Thyrotoxicosis, unspecified	0.016	0.984	0.000
I10 Essential (primary) hypertension	0.014	0.986	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.014	0.986	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.011	0.988	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.989	0.011
K91.9 Postprocedural disorder of digestive system, unspecified	0.011	0.989	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.010	0.990	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.010	0.990	0.000
C15.9 Oesophagus, unspecified	0.010	0.990	0.000
R04.0 Epistaxis	0.000	0.991	0.009
K91.1 Postgastric surgery syndromes	0.009	0.991	0.000
K91.5 Postcholecystectomy syndrome	0.009	0.991	0.000
R81 Glycosuria	0.000	0.992	0.008
D45 Polycythaemia vera	0.000	0.992	0.008
C81.9 Hodgkin's disease, unspecified	0.008	0.992	0.000
K63.1 Perforation of intestine (nontraumatic)	0.008	0.992	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.007	0.993	0.000
C15.3 Upper third of oesophagus	0.007	0.993	0.000
C15 Malignant neoplasm of oesophagus	0.007	0.993	0.000
I46.9 Cardiac arrest, unspecified	0.007	0.993	0.000
O44.1 Placenta praevia with haemorrhage	0.006	0.994	0.000
D37.4 Colon	0.000	0.994	0.006
R82 Other abnormal findings in urine	0.000	0.994	0.006
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.994	0.006
C81 Hodgkin's disease	0.006	0.994	0.000
F40.2 Specific (isolated) phobias	0.000	0.994	0.006
K91.3 Postoperative intestinal obstruction	0.006	0.994	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.994	0.006
C15.1 Thoracic part of oesophagus	0.005	0.994	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.005	0.995	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.995	0.005
C81.2 Mixed cellularity	0.005	0.995	0.000
R82.1 Myoglobinuria	0.000	0.995	0.005
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.995	0.005
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.005	0.995	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.005	0.995	0.000
E05.5 Thyroid crisis or storm	0.005	0.995	0.000
E05.4 Thyrotoxicosis factitia	0.005	0.995	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.005	0.995	0.000
C81.0 Lymphocytic predominance	0.005	0.995	0.000
H54.7 Unspecified visual loss	0.005	0.995	0.000
E05.8 Other thyrotoxicosis	0.005	0.995	0.000
C15.8 Overlapping lesion of oesophagus	0.005	0.995	0.000
C15.2 Abdominal part of oesophagus	0.005	0.995	0.000
C81.1 Nodular sclerosis	0.005	0.995	0.000
D37.5 Rectum	0.000	0.995	0.005
C15.0 Cervical part of oesophagus	0.005	0.995	0.000
S20.2 Contusion of thorax	0.005	0.995	0.000
C15.4 Middle third of oesophagus	0.005	0.995	0.000
D41.4 Bladder	0.000	0.995	0.005
D37.0 Lip, oral cavity and pharynx	0.000	0.995	0.005
D37.6 Liver, gallbladder and bile ducts	0.000	0.995	0.005
D37.9 Digestive organ, unspecified	0.000	0.995	0.005
R80 Isolated proteinuria	0.000	0.995	0.005
R82.4 Acetonuria	0.000	0.995	0.005
C15.5 Lower third of oesophagus	0.005	0.995	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.995	0.005
L27.0 Generalised skin eruption due to drugs and medicaments	0.005	0.995	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.995	0.004
R82.3 Haemoglobinuria	0.000	0.995	0.004
R82.2 Biliuria	0.000	0.995	0.004
R82.0 Chyluria	0.000	0.995	0.004
D37.2 Small intestine	0.000	0.995	0.005
K10.8 Other specified diseases of jaws	0.000	0.995	0.005
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.004	0.996	0.000
C81.3 Lymphocytic depletion	0.004	0.996	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.996	0.004
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.004	0.996	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.000	0.996	0.004
E85.4 Organ-limited amyloidosis	0.000	0.996	0.004
E03.9 Hypothyroidism, unspecified	0.004	0.996	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.996	0.004
D37.1 Stomach	0.000	0.996	0.004
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.996	0.004
C81.7 Other Hodgkin's disease	0.004	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.996	0.004
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.996	0.004
O87.2 Haemorrhoids in the puerperium	0.000	0.996	0.004
D41.2 Ureter	0.000	0.996	0.004
Z71.3 Dietary counselling and surveillance	0.004	0.996	0.000
D37.3 Appendix	0.000	0.996	0.004
S20 Superficial injury of thorax	0.004	0.996	0.000
R06.4 Hyperventilation	0.000	0.996	0.004
S20.4 Other superficial injuries of back wall of thorax	0.004	0.996	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.996	0.004
E85.3 Secondary systemic amyloidosis	0.000	0.996	0.004
K91.4 Colostomy and enterostomy malfunction	0.004	0.996	0.000
E85 Amyloidosis	0.000	0.996	0.004
K10.2 Inflammatory conditions of jaws	0.000	0.997	0.003
K10 Other diseases of jaws	0.000	0.997	0.003
S20.3 Other superficial injuries of front wall of thorax	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
D41.9 Urinary organ, unspecified	0.000	0.997	0.003
D41.7 Other urinary organs	0.000	0.997	0.003
D41.3 Urethra	0.000	0.997	0.003
F40 Phobic anxiety disorders	0.000	0.997	0.003
S20.8 Superficial injuries of other and unspecified parts of thorax	0.003	0.997	0.000
I46 Cardiac arrest	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.997	0.003
D68.2 Hereditary deficiency of other clotting factors	0.000	0.997	0.003
Z31 Procreative management	0.003	0.997	0.000
D41.1 Renal pelvis	0.000	0.997	0.003
D37.7 Other digestive organs	0.000	0.997	0.003
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.997	0.003
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.997	0.003
I46.1 Sudden cardiac death, so described	0.003	0.997	0.000
O86.4 Pyrexia of unknown origin following delivery	0.000	0.997	0.003
S80.9 Superficial injury of lower leg, unspecified	0.000	0.997	0.003
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
Z31.3 Other assisted fertilisation methods	0.003	0.997	0.000
S20.7 Multiple superficial injuries of thorax	0.003	0.997	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.997	0.003
F40.0 Agoraphobia	0.000	0.997	0.003
Z31.8 Other procreative management	0.003	0.997	0.000
D41.0 Kidney	0.000	0.997	0.003
D48.7 Other specified sites	0.000	0.997	0.003
K10.0 Developmental disorders of jaws	0.000	0.997	0.003
K10.9 Disease of jaws, unspecified	0.000	0.997	0.003
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.997	0.003
S20.0 Contusion of breast	0.003	0.997	0.000
D48.0 Bone and articular cartilage	0.000	0.997	0.003
O46.9 Antepartum haemorrhage, unspecified	0.003	0.997	0.000
E85.8 Other amyloidosis	0.000	0.997	0.003
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.997	0.003
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.997	0.003
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.997	0.003
O87 Venous complications in the puerperium	0.000	0.997	0.003
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.997	0.003
O23.4 Unspecified infection of urinary tract in pregnancy	0.003	0.997	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.997	0.003
K10.1 Giant cell granuloma, central	0.000	0.997	0.003
R27.0 Ataxia, unspecified	0.000	0.997	0.003
E03 Other hypothyroidism	0.003	0.997	0.000
D40.0 Prostate	0.000	0.997	0.003
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.997	0.003
C22.1 Intrahepatic bile duct carcinoma	0.003	0.997	0.000
K10.3 Alveolitis of jaws	0.000	0.997	0.003
S46.0 Injury of tendon of the rotator cuff of shoulder	0.003	0.997	0.000
Z31.2 In vitro fertilisation	0.003	0.997	0.000
F40.1 Social phobias	0.000	0.997	0.003
G58.9 Mononeuropathy, unspecified	0.003	0.997	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.997	0.003
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.997	0.003
D48.4 Peritoneum	0.000	0.997	0.003
D34 Benign neoplasm of thyroid gland	0.000	0.997	0.003
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.997	0.003
R27.8 Other and unspecified lack of coordination	0.000	0.997	0.003
Z31.6 General counselling and advice on procreation	0.002	0.997	0.000
Z31.5 Genetic counselling	0.002	0.997	0.000
Z31.1 Artifical insemination	0.002	0.997	0.000
F40.8 Other phobic anxiety disorders	0.000	0.997	0.002
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.000	0.997	0.003
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.997	0.002
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.003	0.997	0.000
K75.4 Autoimmune hepatitis	0.003	0.997	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.997	0.003
D46 Myelodysplastic syndromes	0.000	0.997	0.002
G70.0 Myasthenia gravis	0.003	0.997	0.000
D42.9 Meninges, unspecified	0.000	0.997	0.002
D42.1 Spinal meninges	0.000	0.997	0.002
D42.0 Cerebral meninges	0.000	0.997	0.002
D48.6 Breast	0.000	0.997	0.002
S20.1 Other and unspecified superficial injuries of breast	0.002	0.998	0.000
Z31.4 Procreative investigation and testing	0.002	0.998	0.000
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
O87.8 Other venous complications in the puerperium	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
M84.0 Malunion of fracture	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
D40.9 Male genital organ, unspecified	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
D48.3 Retroperitoneum	0.000	0.998	0.002
E03.0 Congenital hypothyroidism with diffuse goitre	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
G40 Epilepsy	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
G40.8 Other epilepsy	0.000	0.998	0.002
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.998	0.002
Z31.9 Procreative management, unspecified	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
I10-I15 Hypertensive diseases	0.002	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
D38.5 Other respiratory organs	0.000	0.998	0.002
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.998	0.002
G59.0 Diabetic mononeuropathy	0.000	0.998	0.002
O87.3 Cerebral venous thrombosis in the puerperium	0.000	0.998	0.002
O87.1 Deep phlebothrombosis in the puerperium	0.000	0.998	0.002
J34.2 Deviated nasal septum	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
D40.7 Other male genital organs	0.000	0.998	0.002
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.998	0.000
E03.5 Myxoedema coma	0.002	0.998	0.000
E03.4 Atrophy of thyroid (acquired)	0.002	0.998	0.000
E03.3 Postinfectious hypothyroidism	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.002	0.998	0.000
D39.7 Other female genital organs	0.000	0.998	0.002
E23.0 Hypopituitarism	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
J33.8 Other polyp of sinus	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
Z04.5 Examination and observation following other inflicted injury	0.000	0.998	0.002
O86 Other puerperal infections	0.000	0.998	0.002
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.998	0.002
D38.6 Respiratory organ, unspecified	0.000	0.998	0.002
D38.4 Thymus	0.000	0.998	0.002
D38.3 Mediastinum	0.000	0.998	0.002
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.002
E06 Thyroiditis	0.001	0.998	0.002
D38.0 Larynx	0.000	0.998	0.002
O87.9 Venous complication in the puerperium, unspecified	0.000	0.998	0.002
R27 Other lack of coordination	0.000	0.998	0.002
D39.9 Female genital organ, unspecified	0.000	0.998	0.002
D39.2 Placenta	0.000	0.998	0.002
D39.0 Uterus	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.998	0.002
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.998	0.002
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.000	0.998	0.002
D40.1 Testis	0.000	0.998	0.002
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.002
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.002
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.998	0.002
T68 Hypothermia	0.000	0.998	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.002
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
D48.5 Skin	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.002	0.998	0.000
L27.8 Dermatitis due to other substances taken internally	0.002	0.998	0.000
L27.2 Dermatitis due to ingested food	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
K92 Other diseases of digestive system	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
K51.9 Ulcerative colitis, unspecified	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
K92.8 Other specified diseases of digestive system	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.998	0.002
O86.2 Urinary tract infection following delivery	0.000	0.998	0.002
E00-E07 Disorders of thyroid gland	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
E03.1 Congenital hypothyroidism without goitre	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.000	0.998	0.002
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D38.2 Pleura	0.000	0.998	0.002
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
I13 Hypertensive heart and renal disease	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.002	0.998	0.000
O86.8 Other specified puerperal infections	0.000	0.998	0.002
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
E03.8 Other specified hypothyroidism	0.002	0.998	0.000
Z96.2 Presence of otological and audiological implants	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.000	0.998	0.002
G40.5 Special epileptic syndromes	0.000	0.998	0.002
O86.3 Other genito-urinary tract infections following delivery	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.001	0.998	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.998	0.001
E06.1 Subacute thyroiditis	0.000	0.998	0.001
E06.0 Acute thyroiditis	0.001	0.998	0.001
O85 Puerperal sepsis	0.000	0.998	0.002
L65.9 Nonscarring hair loss, unspecified	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
Z71.8 Other specified counselling	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.001	0.998	0.001
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.000	0.998	0.002
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.998	0.002
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.000	0.998	0.002
O85-O92 Complications predominantly related to the puerperium	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.998	0.002
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.998	0.002
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.998	0.002
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
K75.8 Other specified inflammatory liver diseases	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.998	0.002
U80.1 Methicillin resistant agent	0.002	0.998	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.998	0.001
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.001
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.001
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.001	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.001	0.998	0.000
K75.0 Abscess of liver	0.002	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
F22.0 Delusional disorder	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.001	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.001	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.998	0.002
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.998	0.002
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.998	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.001
E27.2 Addisonian crisis	0.002	0.998	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.998	0.001
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
I11 Hypertensive heart disease	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.001	0.998	0.000
L52 Erythema nodosum	0.002	0.998	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.001	0.998	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.001	0.998	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.001	0.998	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.001	0.998	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.001	0.998	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.001	0.998	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.001	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.001	0.998	0.000
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.001
T75.4 Effects of electric current	0.000	0.998	0.001
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.001
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
O81.3 Other and unspecified forceps delivery	0.000	0.998	0.001
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.001	0.998	0.000
T90.1 Sequelae of open wound of head	0.000	0.998	0.001
D25.0 Submucous leiomyoma of uterus	0.000	0.998	0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.001
H54.4 Blindness, one eye	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.001
I15 Secondary hypertension	0.001	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.001	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.001	0.998	0.000
O88 Obstetric embolism	0.000	0.998	0.001
C85.1 B-cell lymphoma, unspecified	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.001	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.001	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.001	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.001	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.001	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.001	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.001	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.001	0.998	0.000
S73.0 Dislocation of hip	0.000	0.998	0.001
E27 Other disorders of adrenal gland	0.001	0.998	0.000
D43.9 Central nervous system, unspecified	0.000	0.999	0.001
D43.7 Other parts of central nervous system	0.000	0.999	0.001
D43.3 Cranial nerves	0.000	0.999	0.001
L23.5 Allergic contact dermatitis due to other chemical products	0.001	0.999	0.000
L23 Allergic contact dermatitis	0.001	0.999	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.001	0.999	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.999	0.001
T90.4 Sequelae of injury of eye and orbit	0.000	0.999	0.001
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.999	0.001
T75 Effects of other external causes	0.000	0.999	0.001
D43.4 Spinal cord	0.000	0.999	0.001
G12.2 Motor neuron disease	0.001	0.999	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.001	0.999	0.000
D47.2 Monoclonal gammopathy	0.000	0.999	0.001
E06.3 Autoimmune thyroiditis	0.000	0.999	0.001
T75.1 Drowning and nonfatal submersion	0.000	0.999	0.001
X59.3 Sports and athletics area	0.000	0.999	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
L23.9 Allergic contact dermatitis, unspecified cause	0.001	0.999	0.000
J47 Bronchiectasis	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
L73.2 Hidradenitis suppurativa	0.000	0.999	0.001
N84.3 Polyp of vulva	0.000	0.999	0.001
S21.1 Open wound of front wall of thorax	0.001	0.999	0.000
O91 Infections of breast associated with childbirth	0.000	0.999	0.001
T70 Effects of air pressure and water pressure	0.000	0.999	0.001
I15.8 Other secondary hypertension	0.001	0.999	0.000
I15.0 Renovascular hypertension	0.001	0.999	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.001	0.999	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.001	0.999	0.000
O69.3 Labour and delivery complicated by short cord	0.001	0.999	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.999	0.001
O89 Complications of anaesthesia during the puerperium	0.000	0.999	0.001
E27.5 Adrenomedullary hyperfunction	0.001	0.999	0.000
E27.0 Other adrenocortical overactivity	0.001	0.999	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.001	0.999	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.001	0.999	0.000
O81.4 Vacuum extractor delivery	0.000	0.999	0.001
O88.8 Other obstetric embolism	0.000	0.999	0.001
O88.3 Obstetric pyaemic and septic embolism	0.000	0.999	0.001
O88.2 Obstetric blood-clot embolism	0.000	0.999	0.001
O88.1 Amniotic fluid embolism	0.000	0.999	0.001
O88.0 Obstetric air embolism	0.000	0.999	0.001
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.999	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.000	0.999	0.001
L23.7 Allergic contact dermatitis due to plants, except food	0.001	0.999	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.001	0.999	0.000
L23.4 Allergic contact dermatitis due to dyes	0.001	0.999	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.001	0.999	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.001	0.999	0.000
L23.0 Allergic contact dermatitis due to metals	0.001	0.999	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.999	0.001
X59.2 School, other institution and public administrative area	0.000	0.999	0.001
D43.1 Brain, infratentorial	0.000	0.999	0.001
D44.9 Endocrine gland, unspecified	0.000	0.999	0.001
D44.5 Pineal gland	0.000	0.999	0.001
D44.2 Parathyroid gland	0.000	0.999	0.001
F17.2 Dependence syndrome	0.001	0.999	0.000
I15.2 Hypertension secondary to endocrine disorders	0.001	0.999	0.000
T75.8 Other specified effects of external causes	0.000	0.999	0.001
T75.3 Motion sickness	0.000	0.999	0.001
T75.2 Effects of vibration	0.000	0.999	0.001
T75.0 Effects of lightning	0.000	0.999	0.001
X59.4 Street and highway	0.000	0.999	0.001
B01.9 Varicella without complications	0.001	0.999	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.999	0.001
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.999	0.001
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
J15.4 Pneumonia due to other streptococci	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
D39.1 Ovary	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations