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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs204899
log Bayes Factor = 16.4982
Chromosome 6   position 32,057,627  (GRCh37) Explore rs204899 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.010 0.990
E11.3 With ophthalmic complications
0.000 0.011 0.989
E65-E68 Obesity and other hyperalimentation
0.000 0.018 0.982
E10.1 With ketoacidosis
0.000 0.020 0.980
E66 Obesity
0.000 0.030 0.970
E14 Unspecified diabetes mellitus
0.000 0.036 0.964
E66.8 Other obesity
0.000 0.044 0.956
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.054 0.946
E14.9 Without complications
0.000 0.077 0.923
E10.5 With peripheral circulatory complications
0.000 0.116 0.884
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.124 0.876
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.124 0.876
E11.5 With peripheral circulatory complications
0.000 0.125 0.875
M06 Other rheumatoid arthritis
0.000 0.125 0.874
E66.9 Obesity, unspecified
0.000 0.136 0.864
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.141 0.859
E11.9 Without complications
0.000 0.150 0.850
E11.4 With neurological complications
0.000 0.165 0.835
E10.4 With neurological complications
0.000 0.171 0.829
E10.2 With renal complications
0.000 0.190 0.810
E14.3 With ophthalmic complications
0.000 0.204 0.796
E05.9 Thyrotoxicosis, unspecified
0.000 0.209 0.791
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.224 0.776
E11.2 With renal complications
0.000 0.225 0.775
E06 Thyroiditis
0.000 0.239 0.761
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.252 0.748
M05-M14 Inflammatory polyarthropathies
0.000 0.256 0.744
M05 Seropositive rheumatoid arthritis
0.000 0.278 0.721
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.716
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
E11.7 With multiple complications
0.000 0.285 0.715
E50-E64 Other nutritional deficiencies
0.000 0.288 0.712
M06.3 Rheumatoid nodule
0.000 0.293 0.707
M06.0 Seronegative rheumatoid arthritis
0.000 0.293 0.706
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.294 0.706
E11.1 With ketoacidosis
0.000 0.294 0.706
E67 Other hyperalimentation
0.000 0.296 0.704
E68 Sequelae of hyperalimentation
0.000 0.296 0.704
E66.1 Drug-induced obesity
0.000 0.304 0.696
E66.0 Obesity due to excess calories
0.000 0.304 0.696
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.308 0.692
E14.8 With unspecified complications
0.000 0.309 0.691
E14.7 With multiple complications
0.000 0.309 0.691
E14.6 With other specified complications
0.000 0.309 0.691
E14.5 With peripheral circulatory complications
0.000 0.309 0.691
E14.4 With neurological complications
0.000 0.309 0.691
E14.2 Withrenal complications
0.000 0.309 0.691
E14.1 With ketoacidosis
0.000 0.309 0.691
E14.0 With coma
0.000 0.309 0.691
E65 Localised adiposity
0.000 0.309 0.691
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.315 0.685
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.317 0.683
E05.8 Other thyrotoxicosis
0.000 0.322 0.678
E05.5 Thyroid crisis or storm
0.000 0.322 0.678
E05.4 Thyrotoxicosis factitia
0.000 0.322 0.678
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.322 0.678
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.322 0.678
E11.8 With unspecified complications
0.000 0.328 0.672
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.345 0.655
E40-E46 Malnutrition
0.000 0.350 0.650
E11.6 With other specified complications
0.000 0.355 0.645
M06.8 Other specified rheumatoid arthritis
0.000 0.373 0.627
M06.2 Rheumatoid bursitis
0.000 0.373 0.627
M06.1 Adult-onset Still's disease
0.000 0.373 0.627
E06.3 Autoimmune thyroiditis
0.000 0.389 0.611
E20-E35 Disorders of other endocrine glands
0.000 0.393 0.607
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.404 0.596
M13 Other arthritis
0.000 0.409 0.591
E11.0 With coma
0.000 0.409 0.590
E07 Other disorders of thyroid
0.000 0.410 0.590
M06.34 Rheumatoid nodule (Hand)
0.000 0.412 0.588
E61 Deficiency of other nutrient elements
0.000 0.424 0.576
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.425 0.575
M14 Arthropathies in other diseases classified elsewhere
0.000 0.429 0.571
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.431 0.569
M10 Gout
0.000 0.442 0.558
E13 Other specified diabetes mellitus
0.000 0.445 0.554
E03.8 Other specified hypothyroidism
0.000 0.448 0.551
E06.5 Other chronic thyroiditis
0.000 0.454 0.546
E06.4 Drug-induced thyroiditis
0.000 0.454 0.546
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.454 0.546
E06.1 Subacute thyroiditis
0.000 0.454 0.546
E06.0 Acute thyroiditis
0.000 0.454 0.546
M12 Other specific arthropathies
0.000 0.466 0.533
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.466 0.533
M08 Juvenile arthritis
0.000 0.466 0.533
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.476 0.524
M05.8 Other seropositive rheumatoid arthritis
0.000 0.483 0.517
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.483 0.517
M05.2 Rheumatoid vasculitis
0.000 0.483 0.517
M05.1 Rheumatoid lung disease
0.000 0.483 0.517
M05.0 Felty's syndrome
0.000 0.483 0.517
E06.9 Thyroiditis, unspecified
0.000 0.483 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E53 Deficiency of other B group vitamins
0.000 0.488 0.511
E27 Other disorders of adrenal gland
0.000 0.489 0.511
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.490 0.510
E63 Other nutritional deficiencies
0.000 0.490 0.510
E56 Other vitamin deficiencies
0.000 0.490 0.510
E51 Thiamine deficiency
0.000 0.490 0.510
E50 Vitamin A deficiency
0.000 0.490 0.510
E60 Dietary zinc deficiency
0.000 0.490 0.510
E59 Dietary selenium deficiency
0.000 0.490 0.510
E58 Dietary calcium deficiency
0.000 0.490 0.510
E54 Ascorbic acid deficiency
0.000 0.490 0.510
E52 Niacin deficiency [pellagra]
0.000 0.490 0.510
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.493 0.507
M06.38 Rheumatoid nodule (Other)
0.000 0.493 0.507
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.493 0.507
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.493 0.507
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.493 0.507
M06.33 Rheumatoid nodule (Forearm)
0.000 0.493 0.507
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.493 0.507
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.493 0.507
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.493 0.507
M06.4 Inflammatory polyarthropathy
0.000 0.493 0.506
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.493 0.507
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.493 0.507
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.493 0.507
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.493 0.507
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.493 0.507
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.493 0.507
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.493 0.507
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.493 0.507
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.494 0.506
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.494 0.506
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.494 0.506
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.494 0.506
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.494 0.506
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.494 0.506
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.494 0.506
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.494 0.506
E67.8 Other specified hyperalimentation
0.000 0.495 0.505
E67.3 Hypervitaminosis D
0.000 0.495 0.505
E67.2 Megavitamin-B6 syndrome
0.000 0.495 0.505
E67.1 Hypercarotenaemia
0.000 0.495 0.505
E67.0 Hypervitaminosis A
0.000 0.495 0.505
M13.0 Polyarthritis, unspecified
0.000 0.503 0.497
E61.1 Iron deficiency
0.000 0.521 0.479
E27.1 Primary adrenocortical insufficiency
0.000 0.523 0.477
E15 Nondiabetic hypoglycaemic coma
0.000 0.530 0.469
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.534 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.534 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.534 0.466
E42 Marasmic kwashiorkor
0.000 0.534 0.466
E41 Nutritional marasmus
0.000 0.534 0.466
E40 Kwashiorkor
0.000 0.534 0.466
E23 Hypofunction and other disorders of pituitary gland
0.000 0.549 0.451
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.550 0.450
M06.18 Adult-onset Still's disease (Other)
0.000 0.550 0.450
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.550 0.450
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.550 0.450
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.550 0.450
M06.14 Adult-onset Still's disease (Hand)
0.000 0.550 0.450
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.550 0.450
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.550 0.450
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.550 0.450
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.550 0.450
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.550 0.450
M06.28 Rheumatoid bursitis (Other)
0.000 0.550 0.450
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.550 0.450
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.550 0.450
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.550 0.450
M06.24 Rheumatoid bursitis (Hand)
0.000 0.550 0.450
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.550 0.450
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.550 0.450
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.550 0.450
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.550 0.450
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.550 0.450
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.550 0.450
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.550 0.450
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.550 0.450
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.550 0.450
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.550 0.450
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.550 0.450
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.550 0.450
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.550 0.450
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.550 0.450
M14.6 Neuropathic arthropathy
0.000 0.553 0.447
M11 Other crystal arthropathies
0.000 0.557 0.442
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.564 0.435
E34 Other endocrine disorders
0.000 0.564 0.435
E32 Diseases of thymus
0.000 0.564 0.435
E31 Polyglandular dysfunction
0.000 0.564 0.435
E30 Disorders of puberty, not elsewhere classified
0.000 0.564 0.435
E25 Adrenogenital disorders
0.000 0.564 0.435
E20 Hypoparathyroidism
0.000 0.564 0.435
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.565 0.435
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.001 0.568 0.431
E28 Ovarian dysfunction
0.000 0.571 0.429
M10.9 Gout, unspecified
0.000 0.576 0.424
M13.8 Other specified arthritis
0.000 0.576 0.424
M13.1 Monoarthritis, not elsewhere classified
0.000 0.576 0.424
E07.1 Dyshormogenetic goitre
0.000 0.577 0.423
E07.0 Hypersecretion of calcitonin
0.000 0.577 0.423
E29 Testicular dysfunction
0.000 0.578 0.422
M07 Psoriatic and enteropathic arthropathies
0.000 0.582 0.417
E61.9 Deficiency of nutrient element, unspecified
0.000 0.587 0.413
E61.8 Deficiency of other specified nutrient elements
0.000 0.587 0.413
E61.7 Deficiency of multiple nutrient elements
0.000 0.587 0.413
E61.6 Vanadium deficiency
0.000 0.587 0.413
E61.5 Molybdenum deficiency
0.000 0.587 0.413
E61.4 Chromium deficiency
0.000 0.587 0.413
E61.3 Manganese deficiency
0.000 0.587 0.413
E61.2 Magnesium deficiency
0.000 0.587 0.413
E61.0 Copper deficiency
0.000 0.587 0.413
E53.8 Deficiency of other specified B group vitamins
0.000 0.587 0.413
E07.8 Other specified disorders of thyroid
0.000 0.589 0.411
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.590 0.409
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.590 0.409
M14.4 Arthropathy in amyloidosis
0.000 0.590 0.409
M14.3 Lipoid dermatoarthritis
0.000 0.590 0.409
M14.2 Diabetic arthropathy
0.000 0.590 0.409
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.590 0.409
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.590 0.409
E16 Other disorders of pancreatic internal secretion
0.000 0.592 0.408
E55 Vitamin D deficiency
0.000 0.597 0.403
M10.4 Other secondary gout
0.000 0.600 0.400
M10.3 Gout due to impairment of renal function
0.000 0.600 0.400
M10.2 Drug-induced gout
0.000 0.600 0.400
M10.1 Lead-induced gout
0.000 0.600 0.400
M10.0 Idiopathic gout
0.000 0.600 0.400
E46 Unspecified protein-energy malnutrition
0.000 0.601 0.399
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.602 0.398
E13.8 With unspecified complications
0.000 0.602 0.397
E13.7 With multiple complications
0.000 0.602 0.397
E13.6 With other specified complications
0.000 0.602 0.397
E13.5 With peripheral circulatory complications
0.000 0.602 0.397
E13.4 With neurological complications
0.000 0.602 0.397
E13.3 With ophthalmic complications
0.000 0.602 0.397
E13.2 With renal complications
0.000 0.602 0.397
E13.1 With ketoacidosis
0.000 0.602 0.397
E13.0 With coma
0.000 0.602 0.397
M13.9 Arthritis, unspecified
0.000 0.603 0.397
E26 Hyperaldosteronism
0.000 0.610 0.390
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.615 0.385
M08.9 Juvenile arthritis, unspecified
0.000 0.617 0.382
M08.8 Other juvenile arthritis
0.000 0.617 0.382
M08.4 Pauciarticular juvenile arthritis
0.000 0.617 0.382
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.617 0.382
M08.2 Juvenile arthritis with systemic onset
0.000 0.617 0.382
M08.1 Juvenile ankylosing spondylitis
0.000 0.617 0.382
M08.0 Juvenile rheumatoid arthritis
0.000 0.617 0.382
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.617 0.382
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.617 0.382
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.617 0.382
M09.0 Juvenile arthritis in psoriasis
0.000 0.617 0.382
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.617 0.382
M12.5 Traumatic arthropathy
0.000 0.617 0.382
M12.4 Intermittent hydrarthrosis
0.000 0.617 0.382
M12.3 Palindromic rheumatism
0.000 0.617 0.382
M12.2 Villonodular synovitis (pigmented)
0.000 0.617 0.382
M12.1 Kaschin-Beck disease
0.000 0.617 0.382
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.617 0.382
E27.8 Other specified disorders of adrenal gland
0.000 0.622 0.377
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.624 0.376
E22 Hyperfunction of pituitary gland
0.000 0.625 0.375
E24 Cushing's syndrome
0.000 0.629 0.371
M05.09 Felty's syndrome (Site unspecified)
0.000 0.629 0.371
M05.08 Felty's syndrome (Other)
0.000 0.629 0.371
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.629 0.371
M05.06 Felty's syndrome (Lower leg)
0.000 0.629 0.371
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.629 0.371
M05.04 Felty's syndrome (Hand)
0.000 0.629 0.371
M05.03 Felty's syndrome (Forearm)
0.000 0.629 0.371
M05.02 Felty's syndrome (Upper arm)
0.000 0.629 0.371
M05.01 Felty's syndrome (Shoulder region)
0.000 0.629 0.371
M05.00 Felty's syndrome (Multiple sites)
0.000 0.629 0.371
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.629 0.371
M05.18 Rheumatoid lung disease (Other)
0.000 0.629 0.371
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.629 0.371
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.629 0.371
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.629 0.371
M05.14 Rheumatoid lung disease (Hand)
0.000 0.629 0.371
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.629 0.371
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.629 0.371
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.629 0.371
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.629 0.371
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.629 0.371
M05.28 Rheumatoid vasculitis (Other)
0.000 0.629 0.371
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.629 0.371
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.629 0.371
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.629 0.371
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.629 0.371
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.629 0.371
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.629 0.371
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.629 0.371
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.629 0.371
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.629 0.371
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.629 0.371
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.629 0.371
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.629 0.371
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.629 0.371
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.629 0.371
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.629 0.371
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.629 0.371
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.629 0.371
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.629 0.371
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.629 0.371
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.629 0.371
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.629 0.371
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.629 0.371
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.629 0.371
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.629 0.371
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.629 0.371
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.629 0.371
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.629 0.371
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.629 0.371
M13.94 Arthritis, unspecified (Hand)
0.000 0.633 0.367
E53.1 Pyridoxine deficiency
0.000 0.633 0.367
E53.0 Riboflavin deficiency
0.000 0.633 0.367
E27.5 Adrenomedullary hyperfunction
0.000 0.633 0.366
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.633 0.366
E27.2 Addisonian crisis
0.000 0.633 0.366
E27.0 Other adrenocortical overactivity
0.000 0.633 0.366
E50.9 Vitamin A deficiency, unspecified
0.000 0.634 0.366
E50.8 Other manifestations of vitamin A deficiency
0.000 0.634 0.366
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.634 0.366
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.634 0.366
E50.5 Vitamin A deficiency with night blindness
0.000 0.634 0.366
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.634 0.366
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.634 0.366
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.634 0.366
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.634 0.366
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.634 0.366
E51.9 Thiamine deficiency, unspecified
0.000 0.634 0.366
E51.8 Other manifestations of thiamine deficiency
0.000 0.634 0.366
E51.2 Wernicke's encephalopathy
0.000 0.634 0.366
E51.1 Beriberi
0.000 0.634 0.366
E56.9 Vitamin deficiency, unspecified
0.000 0.634 0.366
E56.8 Deficiency of other vitamins
0.000 0.634 0.366
E56.1 Deficiency of vitamin K
0.000 0.634 0.366
E56.0 Deficiency of vitamin E
0.000 0.634 0.366
E63.9 Nutritional deficiency, unspecified
0.000 0.634 0.366
E63.8 Other specified nutritional deficiencies
0.000 0.634 0.366
E63.1 Imbalance of constituents of food intake
0.000 0.634 0.366
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.634 0.366
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.634 0.366
E64.8 Sequelae of other nutritional deficiencies
0.000 0.634 0.366
E64.3 Sequelae of rickets
0.000 0.634 0.366
E64.2 Sequelae of vitamin C deficiency
0.000 0.634 0.366
E64.1 Sequelae of vitamin A deficiency
0.000 0.634 0.366
E64.0 Sequelae of protein-energy malnutrition
0.000 0.634 0.366
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.636 0.363
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.636 0.363
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.636 0.363
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.636 0.363
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.636 0.363
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.636 0.363
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.636 0.363
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.636 0.363
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.640 0.360
M13.08 Polyarthritis, unspecified (Other)
0.000 0.644 0.356
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.000 0.644 0.356
M13.06 Polyarthritis, unspecified (Lower leg)
0.000 0.644 0.356
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.000 0.644 0.356
M13.04 Polyarthritis, unspecified (Hand)
0.000 0.644 0.356
M13.03 Polyarthritis, unspecified (Forearm)
0.000 0.644 0.356
M13.02 Polyarthritis, unspecified (Upper arm)
0.000 0.644 0.356
M13.01 Polyarthritis, unspecified (Shoulder region)
0.000 0.644 0.356
E23.2 Diabetes insipidus
0.000 0.646 0.354
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.651 0.349
M13.09 Polyarthritis, unspecified (Site unspecified)
0.000 0.658 0.342
E44.1 Mild protein-energy malnutrition
0.000 0.666 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.666 0.334
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.677 0.323
E23.1 Drug-induced hypopituitarism
0.000 0.677 0.323
E23.7 Disorder of pituitary gland, unspecified
0.000 0.678 0.322
E34.9 Endocrine disorder, unspecified
0.000 0.680 0.320
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.681 0.319
M11.9 Crystal arthropathy, unspecified
0.000 0.682 0.317
M11.8 Other specified crystal arthropathies
0.000 0.682 0.317
M11.1 Familial chondrocalcinosis
0.000 0.682 0.317
M11.0 Hydroxyapatite deposition disease
0.000 0.682 0.317
E23.0 Hypopituitarism
0.000 0.682 0.317
M10.96 Gout, unspecified (Lower leg)
0.000 0.683 0.317
E07.9 Disorder of thyroid, unspecified
0.000 0.683 0.317
E20.9 Hypoparathyroidism, unspecified
0.000 0.688 0.312
E20.8 Other hypoparathyroidism
0.000 0.688 0.312
E20.1 Pseudohypoparathyroidism
0.000 0.688 0.312
E20.0 Idiopathic hypoparathyroidism
0.000 0.688 0.312
E25.9 Adrenogenital disorder, unspecified
0.000 0.688 0.312
E25.8 Other adrenogenital disorders
0.000 0.688 0.312
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.688 0.312
E30.9 Disorder of puberty, unspecified
0.000 0.688 0.312
E30.8 Other disorders of puberty
0.000 0.688 0.312
E30.1 Precocious puberty
0.000 0.688 0.312
E30.0 Delayed puberty
0.000 0.688 0.312
E31.9 Polyglandular dysfunction, unspecified
0.000 0.688 0.312
E31.8 Other polyglandular dysfunction
0.000 0.688 0.312
E31.1 Polyglandular hyperfunction
0.000 0.688 0.312
E31.0 Autoimmune polyglandular failure
0.000 0.688 0.312
E32.9 Disease of thymus, unspecified
0.000 0.688 0.312
E32.8 Other diseases of thymus
0.000 0.688 0.312
E32.1 Abscess of thymus
0.000 0.688 0.312
E32.0 Persistent hyperplasia of thymus
0.000 0.688 0.312
E34.8 Other specified endocrine disorders
0.000 0.688 0.312
E34.5 Androgen resistance syndrome
0.000 0.688 0.312
E34.4 Constitutional tall stature
0.000 0.688 0.312
E34.3 Short stature, not elsewhere classified
0.000 0.688 0.312
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.688 0.312
E34.1 Other hypersecretion of intestinal hormones
0.000 0.688 0.312
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.688 0.312
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.688 0.312
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.688 0.312
E23.6 Other disorders of pituitary gland
0.000 0.689 0.311
M13.93 Arthritis, unspecified (Forearm)
0.000 0.692 0.308
E28.9 Ovarian dysfunction, unspecified
0.000 0.692 0.307
E28.8 Other ovarian dysfunction
0.000 0.692 0.307
E28.3 Primary ovarian failure
0.000 0.692 0.307
E28.1 Androgen excess
0.000 0.692 0.307
E28.0 Oestrogen excess
0.000 0.692 0.307
M13.91 Arthritis, unspecified (Shoulder region)
0.000 0.693 0.307
M10.98 Gout, unspecified (Other)
0.000 0.695 0.304
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.695 0.304
M10.93 Gout, unspecified (Forearm)
0.000 0.695 0.304
M10.92 Gout, unspecified (Upper arm)
0.000 0.695 0.304
M10.91 Gout, unspecified (Shoulder region)
0.000 0.695 0.304
M10.90 Gout, unspecified (Multiple sites)
0.000 0.695 0.304
E34.0 Carcinoid syndrome
0.000 0.696 0.304
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)
0.000 0.696 0.304
M13.18 Monoarthritis, not elsewhere classified (Other)
0.000 0.696 0.304
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)
0.000 0.696 0.304
M13.16 Monoarthritis, not elsewhere classified (Lower leg)
0.000 0.696 0.304
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)
0.000 0.696 0.304
M13.14 Monoarthritis, not elsewhere classified (Hand)
0.000 0.696 0.304
M13.13 Monoarthritis, not elsewhere classified (Forearm)
0.000 0.696 0.304
M13.12 Monoarthritis, not elsewhere classified (Upper arm)
0.000 0.696 0.304
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)
0.000 0.696 0.304
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)
0.000 0.696 0.304
M13.89 Other specified arthritis (Site unspecified)
0.000 0.696 0.304
M13.88 Other specified arthritis (Other)
0.000 0.696 0.304
M13.87 Other specified arthritis (Ankle and foot)
0.000 0.696 0.304
M13.86 Other specified arthritis (Lower leg)
0.000 0.696 0.304
M13.85 Other specified arthritis (Pelvic region and thigh)
0.000 0.696 0.304
M13.84 Other specified arthritis (Hand)
0.000 0.696 0.304
M13.83 Other specified arthritis (Forearm)
0.000 0.696 0.304
M13.82 Other specified arthritis (Upper arm)
0.000 0.696 0.304
M13.81 Other specified arthritis (Shoulder region)
0.000 0.696 0.304
M13.80 Other specified arthritis (Multiple sites)
0.000 0.696 0.304
E29.9 Testicular dysfunction, unspecified
0.000 0.697 0.303
E29.8 Other testicular dysfunction
0.000 0.697 0.303
E29.0 Testicular hyperfunction
0.000 0.697 0.303
E53.9 Vitamin B deficiency, unspecified
0.000 0.699 0.301
E28.2 Polycystic ovarian syndrome
0.000 0.699 0.300
M10.94 Gout, unspecified (Hand)
0.000 0.700 0.300
M07.6 Other enteropathic arthropathies
0.000 0.700 0.299
M07.5 Arthropathy in ulcerative colitis
0.000 0.700 0.299
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.700 0.299
M07.2 Psoriatic spondylitis
0.000 0.700 0.299
M07.1 Arthritis mutilans
0.000 0.700 0.299
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.700 0.299
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.707 0.292
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.707 0.292
E16.4 Abnormal secretion of gastrin
0.000 0.707 0.292
E16.3 Increased secretion of glucagon
0.000 0.707 0.292
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.707 0.292
E29.1 Testicular hypofunction
0.000 0.710 0.290

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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