TreeWAS – Variant ID: rs2056626

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J45.9 Asthma, unspecified	0.000	0.169	0.831
J45 Asthma	0.000	0.548	0.452
J45.8 Mixed asthma	0.000	0.646	0.354
J45.1 Nonallergic asthma	0.000	0.662	0.338
J45.0 Predominantly allergic asthma	0.000	0.666	0.334
E03.9 Hypothyroidism, unspecified	0.309	0.691	0.000
E03 Other hypothyroidism	0.125	0.875	0.000
E03.1 Congenital hypothyroidism without goitre	0.095	0.905	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.090	0.910	0.000
E03.5 Myxoedema coma	0.090	0.910	0.000
E03.4 Atrophy of thyroid (acquired)	0.090	0.910	0.000
E03.3 Postinfectious hypothyroidism	0.090	0.910	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.083	0.917	0.000
E03.8 Other specified hypothyroidism	0.072	0.928	0.000
E00-E07 Disorders of thyroid gland	0.038	0.962	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.038	0.962	0.000
E27 Other disorders of adrenal gland	0.035	0.965	0.000
E06 Thyroiditis	0.034	0.966	0.000
E06.9 Thyroiditis, unspecified	0.031	0.969	0.000
E27.1 Primary adrenocortical insufficiency	0.031	0.969	0.000
E20-E35 Disorders of other endocrine glands	0.030	0.970	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.029	0.971	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.027	0.972	0.000
E00 Congenital iodine-deficiency syndrome	0.027	0.972	0.000
E34 Other endocrine disorders	0.027	0.973	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.027	0.973	0.000
E27.8 Other specified disorders of adrenal gland	0.027	0.973	0.000
E27.2 Addisonian crisis	0.026	0.973	0.000
E07 Other disorders of thyroid	0.026	0.973	0.000
E06.5 Other chronic thyroiditis	0.026	0.974	0.000
E06.1 Subacute thyroiditis	0.026	0.974	0.000
E34.9 Endocrine disorder, unspecified	0.026	0.974	0.000
E26 Hyperaldosteronism	0.025	0.974	0.000
E23 Hypofunction and other disorders of pituitary gland	0.025	0.975	0.000
E27.5 Adrenomedullary hyperfunction	0.025	0.975	0.000
E27.0 Other adrenocortical overactivity	0.025	0.975	0.000
E06.4 Drug-induced thyroiditis	0.025	0.975	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.025	0.975	0.000
E06.0 Acute thyroiditis	0.025	0.975	0.000
E26.0 Primary hyperaldosteronism	0.023	0.977	0.000
E31 Polyglandular dysfunction	0.023	0.977	0.000
E23.2 Diabetes insipidus	0.022	0.978	0.000
E06.3 Autoimmune thyroiditis	0.021	0.978	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.021	0.979	0.000
E32 Diseases of thymus	0.021	0.979	0.000
E30 Disorders of puberty, not elsewhere classified	0.021	0.979	0.000
E34.3 Short stature, not elsewhere classified	0.021	0.979	0.000
E23.0 Hypopituitarism	0.021	0.979	0.000
E34.8 Other specified endocrine disorders	0.021	0.979	0.000
E28 Ovarian dysfunction	0.021	0.979	0.000
E07.9 Disorder of thyroid, unspecified	0.021	0.979	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.021	0.979	0.000
E25 Adrenogenital disorders	0.020	0.979	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.020	0.980	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.020	0.980	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.020	0.980	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.020	0.980	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.020	0.980	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.020	0.980	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.020	0.980	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.020	0.980	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.020	0.980	0.000
E34.5 Androgen resistance syndrome	0.020	0.980	0.000
E34.4 Constitutional tall stature	0.020	0.980	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.020	0.980	0.000
E34.1 Other hypersecretion of intestinal hormones	0.020	0.980	0.000
E24 Cushing's syndrome	0.020	0.980	0.000
E07.1 Dyshormogenetic goitre	0.019	0.981	0.000
E07.0 Hypersecretion of calcitonin	0.019	0.981	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.019	0.981	0.000
E26.8 Other hyperaldosteronism	0.018	0.981	0.000
E26.1 Secondary hyperaldosteronism	0.018	0.981	0.000
E34.0 Carcinoid syndrome	0.018	0.981	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.018	0.981	0.000
E23.1 Drug-induced hypopituitarism	0.018	0.981	0.000
E29 Testicular dysfunction	0.018	0.982	0.000
E23.6 Other disorders of pituitary gland	0.018	0.982	0.000
E31.0 Autoimmune polyglandular failure	0.018	0.982	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.017	0.983	0.000
E26.9 Hyperaldosteronism, unspecified	0.017	0.983	0.000
E20 Hypoparathyroidism	0.017	0.983	0.000
E31.9 Polyglandular dysfunction, unspecified	0.016	0.983	0.000
E31.8 Other polyglandular dysfunction	0.016	0.983	0.000
E31.1 Polyglandular hyperfunction	0.016	0.983	0.000
E28.3 Primary ovarian failure	0.016	0.984	0.000
E07.8 Other specified disorders of thyroid	0.016	0.984	0.000
E30.9 Disorder of puberty, unspecified	0.015	0.984	0.000
E30.8 Other disorders of puberty	0.015	0.984	0.000
E30.1 Precocious puberty	0.015	0.984	0.000
E30.0 Delayed puberty	0.015	0.984	0.000
E32.9 Disease of thymus, unspecified	0.015	0.984	0.000
E32.8 Other diseases of thymus	0.015	0.984	0.000
E32.1 Abscess of thymus	0.015	0.984	0.000
E32.0 Persistent hyperplasia of thymus	0.015	0.984	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.015	0.984	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.015	0.984	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.015	0.984	0.000
E23.7 Disorder of pituitary gland, unspecified	0.015	0.985	0.000
E28.9 Ovarian dysfunction, unspecified	0.015	0.985	0.000
E28.8 Other ovarian dysfunction	0.015	0.985	0.000
E28.1 Androgen excess	0.015	0.985	0.000
E28.0 Oestrogen excess	0.015	0.985	0.000
E21.2 Other hyperparathyroidism	0.015	0.985	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.985	0.015
E25.9 Adrenogenital disorder, unspecified	0.015	0.985	0.000
E25.8 Other adrenogenital disorders	0.015	0.985	0.000
E24.9 Cushing's syndrome, unspecified	0.015	0.985	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.015	0.985	0.000
E21.4 Other specified disorders of parathyroid gland	0.014	0.985	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.014	0.986	0.000
E24.3 Ectopic ACTH syndrome	0.014	0.986	0.000
E24.1 Nelson's syndrome	0.014	0.986	0.000
E22 Hyperfunction of pituitary gland	0.014	0.986	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.014	0.986	0.000
E27.9 Disorder of adrenal gland, unspecified	0.014	0.986	0.000
E24.0 Pituitary-dependent Cushing's disease	0.014	0.986	0.000
E28.2 Polycystic ovarian syndrome	0.014	0.986	0.000
E24.8 Other Cushing's syndrome	0.014	0.986	0.000
E29.8 Other testicular dysfunction	0.013	0.986	0.000
E29.0 Testicular hyperfunction	0.013	0.986	0.000
E29.9 Testicular dysfunction, unspecified	0.013	0.987	0.000
E40-E46 Malnutrition	0.013	0.987	0.000
E20.1 Pseudohypoparathyroidism	0.013	0.987	0.000
J43 Emphysema	0.000	0.987	0.013
J43.2 Centrilobular emphysema	0.000	0.987	0.013
Z22.3 Carrier of other specified bacterial diseases	0.000	0.987	0.013
E24.2 Drug-induced Cushing's syndrome	0.013	0.987	0.000
E20.8 Other hypoparathyroidism	0.012	0.987	0.000
E20.0 Idiopathic hypoparathyroidism	0.012	0.987	0.000
E65-E68 Obesity and other hyperalimentation	0.012	0.988	0.000
J46 Status asthmaticus	0.000	0.989	0.011
E22.9 Hyperfunction of pituitary gland, unspecified	0.011	0.989	0.000
Y43.4 Immunosuppressive agents	0.011	0.989	0.000
H52.0 Hypermetropia	0.011	0.989	0.000
E21.0 Primary hyperparathyroidism	0.011	0.989	0.000
E15 Nondiabetic hypoglycaemic coma	0.011	0.989	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.989	0.011
E16 Other disorders of pancreatic internal secretion	0.011	0.989	0.000
H52.3 Anisometropia and aniseikonia	0.011	0.989	0.000
E29.1 Testicular hypofunction	0.010	0.989	0.000
E22.8 Other hyperfunction of pituitary gland	0.010	0.990	0.000
H52 Disorders of refraction and accommodation	0.010	0.990	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.010	0.990	0.000
J43.8 Other emphysema	0.000	0.990	0.010
E65 Localised adiposity	0.010	0.990	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.010	0.990	0.000
E45 Retarded development following protein-energy malnutrition	0.010	0.990	0.000
E43 Unspecified severe protein-energy malnutrition	0.010	0.990	0.000
E42 Marasmic kwashiorkor	0.010	0.990	0.000
E41 Nutritional marasmus	0.010	0.990	0.000
E40 Kwashiorkor	0.010	0.990	0.000
E22.0 Acromegaly and pituitary gigantism	0.010	0.990	0.000
J43.1 Panlobular emphysema	0.000	0.990	0.009
J43.0 MacLeod's syndrome	0.000	0.990	0.009
E16.1 Other hypoglycaemia	0.009	0.991	0.000
H52.4 Presbyopia	0.009	0.991	0.000
E22.1 Hyperprolactinaemia	0.009	0.991	0.000
H52.1 Myopia	0.009	0.991	0.000
E67 Other hyperalimentation	0.008	0.991	0.000
E68 Sequelae of hyperalimentation	0.008	0.991	0.000
E46 Unspecified protein-energy malnutrition	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
H52.7 Disorder of refraction, unspecified	0.008	0.992	0.000
E21.3 Hyperparathyroidism, unspecified	0.008	0.992	0.000
J47 Bronchiectasis	0.000	0.992	0.008
Z22.5 Carrier of viral hepatitis	0.008	0.992	0.000
E05.9 Thyrotoxicosis, unspecified	0.008	0.992	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.992	0.008
J41.1 Mucopurulent chronic bronchitis	0.000	0.992	0.008
E16.9 Disorder of pancreatic internal secretion, unspecified	0.008	0.992	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.008	0.992	0.000
E16.4 Abnormal secretion of gastrin	0.008	0.992	0.000
E16.3 Increased secretion of glucagon	0.008	0.992	0.000
H52.6 Other disorders of refraction	0.008	0.992	0.000
H52.5 Disorders of accommodation	0.008	0.992	0.000
E05.5 Thyroid crisis or storm	0.007	0.992	0.000
E05.4 Thyrotoxicosis factitia	0.007	0.992	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.007	0.992	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.007	0.992	0.000
J41.0 Simple chronic bronchitis	0.000	0.992	0.007
E05.8 Other thyrotoxicosis	0.007	0.993	0.000
O02.1 Missed abortion	0.000	0.993	0.007
E44.1 Mild protein-energy malnutrition	0.007	0.993	0.000
E44.0 Moderate protein-energy malnutrition	0.007	0.993	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.006	0.993	0.001
J42 Unspecified chronic bronchitis	0.000	0.993	0.007
E54 Ascorbic acid deficiency	0.007	0.993	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.007	0.993	0.000
E67.8 Other specified hyperalimentation	0.006	0.994	0.000
E67.3 Hypervitaminosis D	0.006	0.994	0.000
E67.2 Megavitamin-B6 syndrome	0.006	0.994	0.000
E67.1 Hypercarotenaemia	0.006	0.994	0.000
E67.0 Hypervitaminosis A	0.006	0.994	0.000
E51 Thiamine deficiency	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
B18.2 Chronic viral hepatitis C	0.006	0.994	0.000
E61 Deficiency of other nutrient elements	0.006	0.994	0.000
E11.6 With other specified complications	0.006	0.994	0.000
H52.2 Astigmatism	0.006	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.006	0.994	0.000
E16.2 Hypoglycaemia, unspecified	0.006	0.994	0.000
E80.4 Gilbert's syndrome	0.006	0.994	0.000
J04.0 Acute laryngitis	0.000	0.994	0.006
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.005	0.995	0.000
E11.2 With renal complications	0.005	0.995	0.000
H43.1 Vitreous haemorrhage	0.005	0.995	0.000
Z22 Carrier of infectious disease	0.004	0.995	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.005	0.995	0.000
N26 Unspecified contracted kidney	0.005	0.995	0.000
E51.2 Wernicke's encephalopathy	0.005	0.995	0.000
E53.9 Vitamin B deficiency, unspecified	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.005	0.995	0.000
E51.8 Other manifestations of thiamine deficiency	0.005	0.995	0.000
E51.1 Beriberi	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.005	0.995	0.000
E50.8 Other manifestations of vitamin A deficiency	0.005	0.995	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.005	0.995	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.005	0.995	0.000
E50.5 Vitamin A deficiency with night blindness	0.005	0.995	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.005	0.995	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.005	0.995	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.005	0.995	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.005	0.995	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.005	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.005	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.005	0.995	0.000
E63.1 Imbalance of constituents of food intake	0.005	0.995	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.005	0.995	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.005	0.995	0.000
E64.8 Sequelae of other nutritional deficiencies	0.005	0.995	0.000
E64.3 Sequelae of rickets	0.005	0.995	0.000
E64.2 Sequelae of vitamin C deficiency	0.005	0.995	0.000
E64.1 Sequelae of vitamin A deficiency	0.005	0.995	0.000
E64.0 Sequelae of protein-energy malnutrition	0.005	0.995	0.000
E61.1 Iron deficiency	0.005	0.995	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.005	0.995	0.000
E10-E14 Diabetes mellitus	0.005	0.995	0.000
K90.0 Coeliac disease	0.000	0.995	0.005
E80.1 Porphyria cutanea tarda	0.004	0.995	0.000
Z29.8 Other specified prophylactic measures	0.005	0.995	0.000
E61.9 Deficiency of nutrient element, unspecified	0.004	0.996	0.000
E61.8 Deficiency of other specified nutrient elements	0.004	0.996	0.000
E61.7 Deficiency of multiple nutrient elements	0.004	0.996	0.000
E61.6 Vanadium deficiency	0.004	0.996	0.000
E61.5 Molybdenum deficiency	0.004	0.996	0.000
E61.4 Chromium deficiency	0.004	0.996	0.000
E61.3 Manganese deficiency	0.004	0.996	0.000
E61.0 Copper deficiency	0.004	0.996	0.000
E80.2 Other porphyria	0.004	0.996	0.000
E56.9 Vitamin deficiency, unspecified	0.004	0.996	0.000
E56.8 Deficiency of other vitamins	0.004	0.996	0.000
E56.0 Deficiency of vitamin E	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.004	0.996	0.000
E53.0 Riboflavin deficiency	0.004	0.996	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.004	0.996	0.000
A49.0 Staphylococcal infection, unspecified	0.004	0.996	0.000
I27.2 Other secondary pulmonary hypertension	0.004	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
K62.6 Ulcer of anus and rectum	0.000	0.996	0.004
K72.0 Acute and subacute hepatic failure	0.004	0.996	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.003	0.996	0.001
Z22.9 Carrier of infectious disease, unspecified	0.003	0.996	0.001
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.003	0.996	0.001
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.003	0.996	0.001
Z22.2 Carrier of diphtheria	0.003	0.996	0.001
Z22.0 Carrier of typhoid	0.003	0.996	0.001
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
E80.5 Crigler-Najjar syndrome	0.004	0.996	0.000
E80.3 Defects of catalase and peroxydase	0.004	0.996	0.000
E80.0 Hereditary erythropoietic porphyria	0.004	0.996	0.000
E56.1 Deficiency of vitamin K	0.003	0.996	0.000
E11 Non-insulin-dependent diabetes mellitus	0.004	0.996	0.000
Z22.8 Carrier of other infectious diseases	0.003	0.996	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.996	0.001
M47.99 Spondylosis, unspecified (Site unspecified)	0.004	0.996	0.000
E12 Malnutrition-related diabetes mellitus	0.003	0.996	0.000
E61.2 Magnesium deficiency	0.003	0.996	0.000
J43.9 Emphysema, unspecified	0.000	0.996	0.004
E80.6 Other disorders of bilirubin metabolism	0.003	0.997	0.000
E70-E90 Metabolic disorders	0.003	0.997	0.000
E55.0 Rickets, active	0.003	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
B18 Chronic viral hepatitis	0.003	0.997	0.000
E11.7 With multiple complications	0.003	0.997	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.003	0.997	0.000
E12.9 Without complications	0.003	0.997	0.000
E12.8 With unspecified complications	0.003	0.997	0.000
E12.7 With multiple complications	0.003	0.997	0.000
E12.6 With other specified complications	0.003	0.997	0.000
E12.5 With peripheral circulatory complications	0.003	0.997	0.000
E12.4 With neurological complications	0.003	0.997	0.000
E12.3 With ophthalmic complications	0.003	0.997	0.000
E12.2 With renal complications	0.003	0.997	0.000
E12.1 With ketoacidosis	0.003	0.997	0.000
E12.0 With coma	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
E85 Amyloidosis	0.003	0.997	0.000
E72 Other disorders of amino-acid metabolism	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.997	0.000
E11.8 With unspecified complications	0.003	0.997	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
E04 Other non-toxic goitre	0.003	0.997	0.000
E11.0 With coma	0.003	0.997	0.000
E77 Disorders of glycoprotein metabolism	0.003	0.997	0.000
E76 Disorders of glycosaminoglycan metabolism	0.003	0.997	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.003	0.997	0.000
E70 Disorders of aromatic amino-acid metabolism	0.003	0.997	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.003	0.997	0.000
E75.5 Other lipid storage disorders	0.003	0.997	0.000
E75.2 Other sphingolipidosis	0.002	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
F52.2 Failure of genital response	0.000	0.997	0.003
E79 Disorders of purine and pyrimidine metabolism	0.002	0.997	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.997	0.003
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.997	0.003
E84 Cystic fibrosis	0.002	0.997	0.000
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
Z29 Need for other prophylactic measures	0.002	0.997	0.000
B18.9 Chronic viral hepatitis, unspecified	0.002	0.997	0.000
B18.8 Other chronic viral hepatitis	0.002	0.997	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.002	0.997	0.000
E85.9 Amyloidosis, unspecified	0.002	0.997	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.997	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
E72.0 Disorders of amino-acid transport	0.002	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.002	0.998	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.002	0.998	0.000
E75.3 Sphingolipidosis, unspecified	0.002	0.998	0.000
E75.1 Other gangliosidosis	0.002	0.998	0.000
E75.0 GM2 gangliosidosis	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.000	0.998	0.002
J44 Other chronic obstructive pulmonary disease	0.000	0.998	0.002
A48.1 Legionnaires' disease	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
E85.8 Other amyloidosis	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E73 Lactose intolerance	0.002	0.998	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.002	0.998	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.002	0.998	0.000
E72.5 Disorders of glycine metabolism	0.002	0.998	0.000
E72.4 Disorders of ornithine metabolism	0.002	0.998	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.002	0.998	0.000
E72.2 Disorders of urea cycle metabolism	0.002	0.998	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.002	0.998	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E70.3 Albinism	0.002	0.998	0.000
E70.2 Disorders of tyrosine metabolism	0.002	0.998	0.000
E70.1 Other hyperphenylalaninaemias	0.002	0.998	0.000
E70.0 Classical phenylketonuria	0.002	0.998	0.000
E71.3 Disorders of fatty-acid metabolism	0.002	0.998	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.002	0.998	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.002	0.998	0.000
E71.0 Maple-syrup-urine disease	0.002	0.998	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.002	0.998	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.002	0.998	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.002	0.998	0.000
E76.2 Other mucopolysaccharidoses	0.002	0.998	0.000
E76.1 Mucopolysaccharidosis, type II	0.002	0.998	0.000
E76.0 Mucopolysaccharidosis, type I	0.002	0.998	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.002	0.998	0.000
E77.8 Other disorders of glycoprotein metabolism	0.002	0.998	0.000
E77.1 Defects in glycoprotein degradation	0.002	0.998	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
E11.1 With ketoacidosis	0.002	0.998	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.002	0.998	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
E79.1 Lesch-Nyhan syndrome	0.002	0.998	0.000
O02 Other abnormal products of conception	0.000	0.998	0.002
A49.2 Haemophilus influenzae infection, unspecified	0.002	0.998	0.000
E84.8 Cystic fibrosis with other manifestations	0.002	0.998	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.002	0.998	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.002	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.002	0.998	0.000
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
R63.1 Polydipsia	0.000	0.998	0.002
Z46.7 Fitting and adjustment of orthopaedic device	0.002	0.998	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.002	0.998	0.000
L60.0 Ingrowing nail	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
R03.1 Nonspecific low blood-pressure reading	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.002	0.998	0.000
W02.9 Unspecified place	0.000	0.998	0.002
Z28 Immunisation not carried out	0.002	0.998	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.002	0.998	0.000
Z25 Need for immunisation against other single viral diseases	0.002	0.998	0.000
Z23 Need for immunisation against single bacterial diseases	0.002	0.998	0.000
Z20 Contact with and exposure to communicable diseases	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
Z26 Need for immunisation against other single infectious diseases	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
E73.8 Other lactose intolerance	0.002	0.998	0.000
E73.1 Secondary lactase deficiency	0.002	0.998	0.000
E73.0 Congenital lactase deficiency	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.002	0.998	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.002	0.998	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.002	0.998	0.000
E74.2 Disorders of galactose metabolism	0.002	0.998	0.000
E74.1 Disorders of fructose metabolism	0.002	0.998	0.000
Z24 Need for immunisation against certain single viral diseases	0.001	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.998	0.002
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
E10.8 With unspecified complications	0.002	0.998	0.000
A49.3 Mycoplasma infection, unspecified	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.000	0.998	0.002
E74.0 Glycogen storage disease	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
M43.1 Spondylolisthesis	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.000	0.998	0.002
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
J04 Acute laryngitis and tracheitis	0.000	0.998	0.002
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
W10.8 Other specified place	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.001	0.998	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.001	0.998	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.001	0.998	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.001	0.998	0.000
Z20.4 Contact with and exposure to rubella	0.001	0.998	0.000
Z20.3 Contact with and exposure to rabies	0.001	0.998	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.001	0.998	0.000
Z20.1 Contact with and exposure to tuberculosis	0.001	0.998	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.001	0.998	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.001	0.998	0.000
Z23.7 Need for immunisation against pertussis alone	0.001	0.998	0.000
Z23.6 Need for immunisation against diphtheria alone	0.001	0.998	0.000
Z23.5 Need for immunisation against tetanus alone	0.001	0.998	0.000
Z23.4 Need for immunisation against tularaemia	0.001	0.998	0.000
Z23.3 Need for immunisation against plague	0.001	0.998	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.001	0.998	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.001	0.998	0.000
Z23.0 Need for immunisation against cholera alone	0.001	0.998	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.001	0.998	0.000
Z25.1 Need for immunisation against influenza	0.001	0.998	0.000
Z25.0 Need for immunisation against mumps alone	0.001	0.998	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.001	0.998	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.001	0.998	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.001	0.998	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.001	0.998	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.001	0.998	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.001	0.998	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.001	0.998	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.001	0.998	0.000
Z28.8 Immunisation not carried out for other reasons	0.001	0.998	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.001	0.998	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.001	0.998	0.000
Z28.0 Immunisation not carried out because of contraindication	0.001	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
Z20.8 Contact with and exposure to other communicable diseases	0.001	0.998	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.001	0.998	0.000
Z26.0 Need for immunisation against leishmaniasis	0.001	0.998	0.000
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
U51 Admission status on psychiatric patients	0.002	0.998	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.998	0.001
Z26.9 Need for immunisation against unspecified infectious disease	0.001	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations