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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2073724
log Bayes Factor = 16.2914
Chromosome 6   position 31,129,707  (GRCh37) Explore rs2073724 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.269 0.731
K90 Intestinal malabsorption
0.000 0.283 0.716
R31 Unspecified haematuria
0.681 0.319 0.000
J45 Asthma
0.013 0.388 0.599
K90.9 Intestinal malabsorption, unspecified
0.000 0.427 0.573
J45.0 Predominantly allergic asthma
0.003 0.432 0.566
K90.8 Other intestinal malabsorption
0.000 0.486 0.514
K90.3 Pancreatic steatorrhoea
0.000 0.486 0.514
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.486 0.514
K90.1 Tropical sprue
0.000 0.486 0.514
K90-K93 Other diseases of the digestive system
0.000 0.499 0.501
E03 Other hypothyroidism
0.485 0.514 0.001
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.553 0.447
K92 Other diseases of digestive system
0.000 0.558 0.442
J45.8 Mixed asthma
0.010 0.561 0.429
J45.1 Nonallergic asthma
0.010 0.561 0.429
K92.1 Melaena
0.000 0.598 0.402
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.602 0.398
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.604 0.396
K91.3 Postoperative intestinal obstruction
0.000 0.627 0.372
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.641 0.359
E03.5 Myxoedema coma
0.348 0.651 0.001
E03.4 Atrophy of thyroid (acquired)
0.348 0.651 0.001
E03.3 Postinfectious hypothyroidism
0.348 0.651 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.348 0.651 0.001
E03.1 Congenital hypothyroidism without goitre
0.348 0.651 0.001
E03.0 Congenital hypothyroidism with diffuse goitre
0.348 0.651 0.001
E78.0 Pure hypercholesterolaemia
0.347 0.653 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.686 0.314
K92.9 Disease of digestive system, unspecified
0.000 0.690 0.310
K92.8 Other specified diseases of digestive system
0.000 0.708 0.292
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.716 0.284
K91.5 Postcholecystectomy syndrome
0.000 0.716 0.284
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.716 0.284
E03.8 Other specified hypothyroidism
0.283 0.716 0.001
J47 Bronchiectasis
0.270 0.730 0.001
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.742 0.258
K93.1 Megacolon in Chagas' disease
0.000 0.742 0.258
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.742 0.258
K91.1 Postgastric surgery syndromes
0.000 0.756 0.244
E00-E07 Disorders of thyroid gland
0.235 0.764 0.001
J40-J47 Chronic lower respiratory diseases
0.162 0.776 0.061
E06 Thyroiditis
0.203 0.797 0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.800 0.200
E10.9 Without complications
0.000 0.800 0.200
K91.4 Colostomy and enterostomy malfunction
0.000 0.805 0.194
E10 Insulin-dependent diabetes mellitus
0.000 0.819 0.181
E07 Other disorders of thyroid
0.176 0.823 0.001
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.172 0.827 0.000
E06.3 Autoimmune thyroiditis
0.170 0.830 0.000
J42 Unspecified chronic bronchitis
0.152 0.830 0.018
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.168 0.831 0.001
E00 Congenital iodine-deficiency syndrome
0.168 0.831 0.001
E02 Subclinical iodine-deficiency hypothyroidism
0.168 0.831 0.001
J40 Bronchitis, not specified as acute or chronic
0.159 0.833 0.008
E06.9 Thyroiditis, unspecified
0.163 0.837 0.000
J41 Simple and mucopurulent chronic bronchitis
0.117 0.839 0.044
E10.3 With ophthalmic complications
0.000 0.842 0.158
K92.0 Haematemesis
0.000 0.850 0.150
E06.5 Other chronic thyroiditis
0.146 0.854 0.001
E06.4 Drug-induced thyroiditis
0.146 0.854 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.146 0.854 0.001
E06.1 Subacute thyroiditis
0.146 0.854 0.001
E06.0 Acute thyroiditis
0.146 0.854 0.001
E10.4 With neurological complications
0.000 0.856 0.143
E10.1 With ketoacidosis
0.000 0.859 0.141
E78.4 Other hyperlipidaemia
0.136 0.864 0.000
E07.9 Disorder of thyroid, unspecified
0.134 0.865 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.128 0.866 0.007
E10-E14 Diabetes mellitus
0.007 0.867 0.127
J43 Emphysema
0.074 0.867 0.059
E10.8 With unspecified complications
0.000 0.870 0.130
E10.7 With multiple complications
0.000 0.870 0.130
E10.6 With other specified complications
0.000 0.870 0.130
E10.0 With coma
0.000 0.870 0.130
E10.2 With renal complications
0.000 0.870 0.129
E70-E90 Metabolic disorders
0.127 0.871 0.001
E10.5 With peripheral circulatory complications
0.000 0.872 0.128
E78.9 Disorder of lipoprotein metabolism, unspecified
0.128 0.872 0.000
E07.8 Other specified disorders of thyroid
0.126 0.873 0.001
E07.1 Dyshormogenetic goitre
0.126 0.873 0.001
E07.0 Hypersecretion of calcitonin
0.126 0.873 0.001
E78.6 Lipoprotein deficiency
0.124 0.876 0.000
E78.3 Hyperchylomicronaemia
0.124 0.876 0.000
E78.1 Pure hyperglyceridaemia
0.124 0.876 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.121 0.878 0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.121 0.878 0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.121 0.878 0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.121 0.878 0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.121 0.878 0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.121 0.878 0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.121 0.878 0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.121 0.878 0.001
E78.8 Other disorders of lipoprotein metabolism
0.119 0.881 0.000
E14 Unspecified diabetes mellitus
0.002 0.881 0.117
J46 Status asthmaticus
0.061 0.884 0.054
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.084 0.885 0.032
J41.1 Mucopurulent chronic bronchitis
0.084 0.885 0.032
J41.0 Simple chronic bronchitis
0.084 0.885 0.032
E04 Other non-toxic goitre
0.107 0.893 0.000
E78.2 Mixed hyperlipidaemia
0.107 0.893 0.000
E13 Other specified diabetes mellitus
0.004 0.895 0.101
I21.9 Acute myocardial infarction, unspecified
0.103 0.897 0.000
E40-E46 Malnutrition
0.099 0.897 0.004
E14.3 With ophthalmic complications
0.001 0.897 0.102
E65-E68 Obesity and other hyperalimentation
0.100 0.897 0.003
E14.9 Without complications
0.000 0.899 0.101
E83 Disorders of mineral metabolism
0.099 0.900 0.001
E05 Thyrotoxicosis [hyperthyroidism]
0.098 0.902 0.001
E12 Malnutrition-related diabetes mellitus
0.005 0.904 0.091
J43.8 Other emphysema
0.053 0.905 0.042
J43.1 Panlobular emphysema
0.053 0.905 0.042
J43.0 MacLeod's syndrome
0.053 0.905 0.042
E80 Disorders of porphyrin and bilirubin metabolism
0.094 0.905 0.001
E74 Other disorders of carbohydrate metabolism
0.093 0.906 0.001
J43.2 Centrilobular emphysema
0.055 0.906 0.039
E84 Cystic fibrosis
0.091 0.907 0.001
E79 Disorders of purine and pyrimidine metabolism
0.091 0.907 0.001
E77 Disorders of glycoprotein metabolism
0.091 0.907 0.001
E76 Disorders of glycosaminoglycan metabolism
0.091 0.907 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.091 0.907 0.001
E72 Other disorders of amino-acid metabolism
0.091 0.907 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.091 0.907 0.001
E70 Disorders of aromatic amino-acid metabolism
0.091 0.907 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.091 0.907 0.001
E83.4 Disorders of magnesium metabolism
0.091 0.909 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.090 0.909 0.001
E85 Amyloidosis
0.088 0.911 0.001
E65 Localised adiposity
0.084 0.914 0.001
E14.8 With unspecified complications
0.001 0.915 0.084
E14.7 With multiple complications
0.001 0.915 0.084
E14.6 With other specified complications
0.001 0.915 0.084
E14.5 With peripheral circulatory complications
0.001 0.915 0.084
E14.4 With neurological complications
0.001 0.915 0.084
E14.2 Withrenal complications
0.001 0.915 0.084
E14.1 With ketoacidosis
0.001 0.915 0.084
E14.0 With coma
0.001 0.915 0.084
E13.9 Without complications
0.002 0.916 0.082
I21 Acute myocardial infarction
0.084 0.916 0.000
E73 Lactose intolerance
0.080 0.919 0.001
E46 Unspecified protein-energy malnutrition
0.079 0.919 0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.075 0.920 0.005
E50-E64 Other nutritional deficiencies
0.075 0.921 0.005
E83.3 Disorders of phosphorus metabolism
0.077 0.922 0.001
E04.8 Other specified non-toxic goitre
0.077 0.923 0.000
I20-I25 Ischaemic heart diseases
0.077 0.923 0.000
E04.0 Non-toxic diffuse goitre
0.076 0.923 0.000
I20 Angina pectoris
0.076 0.924 0.000
E13.8 With unspecified complications
0.003 0.925 0.072
E13.7 With multiple complications
0.003 0.925 0.072
E13.6 With other specified complications
0.003 0.925 0.072
E13.5 With peripheral circulatory complications
0.003 0.925 0.072
E13.4 With neurological complications
0.003 0.925 0.072
E13.3 With ophthalmic complications
0.003 0.925 0.072
E13.2 With renal complications
0.003 0.925 0.072
E13.1 With ketoacidosis
0.003 0.925 0.072
E13.0 With coma
0.003 0.925 0.072
E44 Protein-energy malnutrition of moderate and mild degree
0.071 0.926 0.003
E45 Retarded development following protein-energy malnutrition
0.071 0.926 0.003
E43 Unspecified severe protein-energy malnutrition
0.071 0.926 0.003
E42 Marasmic kwashiorkor
0.071 0.926 0.003
E41 Nutritional marasmus
0.071 0.926 0.003
E40 Kwashiorkor
0.071 0.926 0.003
I20.9 Angina pectoris, unspecified
0.074 0.926 0.000
E67 Other hyperalimentation
0.072 0.926 0.002
E68 Sequelae of hyperalimentation
0.072 0.926 0.002
E83.9 Disorder of mineral metabolism, unspecified
0.071 0.928 0.001
E83.8 Other disorders of mineral metabolism
0.071 0.928 0.001
E83.2 Disorders of zinc metabolism
0.071 0.928 0.001
E83.0 Disorders of copper metabolism
0.071 0.928 0.001
I21.0 Acute transmural myocardial infarction of anterior wall
0.071 0.929 0.000
E05.8 Other thyrotoxicosis
0.070 0.929 0.001
E05.5 Thyroid crisis or storm
0.070 0.929 0.001
E05.4 Thyrotoxicosis factitia
0.070 0.929 0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.070 0.929 0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.070 0.929 0.001
E80.4 Gilbert's syndrome
0.070 0.929 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.069 0.930 0.001
E83.5 Disorders of calcium metabolism
0.069 0.930 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.069 0.930 0.001
E12.9 Without complications
0.004 0.931 0.065
E12.8 With unspecified complications
0.004 0.931 0.065
E12.7 With multiple complications
0.004 0.931 0.065
E12.6 With other specified complications
0.004 0.931 0.065
E12.5 With peripheral circulatory complications
0.004 0.931 0.065
E12.4 With neurological complications
0.004 0.931 0.065
E12.3 With ophthalmic complications
0.004 0.931 0.065
E12.2 With renal complications
0.004 0.931 0.065
E12.1 With ketoacidosis
0.004 0.931 0.065
E12.0 With coma
0.004 0.931 0.065
E89.2 Postprocedural hypoparathyroidism
0.068 0.931 0.001
E89.0 Postprocedural hypothyroidism
0.068 0.932 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.068 0.932 0.001
E80.6 Other disorders of bilirubin metabolism
0.068 0.932 0.001
E80.5 Crigler-Najjar syndrome
0.068 0.932 0.001
E80.3 Defects of catalase and peroxydase
0.068 0.932 0.001
E80.2 Other porphyria
0.068 0.932 0.001
E80.1 Porphyria cutanea tarda
0.068 0.932 0.001
E80.0 Hereditary erythropoietic porphyria
0.068 0.932 0.001
E88 Other metabolic disorders
0.067 0.932 0.002
E74.9 Disorder of carbohydrate metabolism, unspecified
0.067 0.932 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.067 0.932 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.067 0.932 0.001
E74.2 Disorders of galactose metabolism
0.067 0.932 0.001
E74.1 Disorders of fructose metabolism
0.067 0.932 0.001
E74.0 Glycogen storage disease
0.067 0.932 0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.066 0.933 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.066 0.933 0.001
E70.3 Albinism
0.066 0.933 0.001
E70.2 Disorders of tyrosine metabolism
0.066 0.933 0.001
E70.1 Other hyperphenylalaninaemias
0.066 0.933 0.001
E70.0 Classical phenylketonuria
0.066 0.933 0.001
E71.3 Disorders of fatty-acid metabolism
0.066 0.933 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.066 0.933 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.066 0.933 0.001
E71.0 Maple-syrup-urine disease
0.066 0.933 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.066 0.933 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.066 0.933 0.001
E72.5 Disorders of glycine metabolism
0.066 0.933 0.001
E72.4 Disorders of ornithine metabolism
0.066 0.933 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.066 0.933 0.001
E72.2 Disorders of urea cycle metabolism
0.066 0.933 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.066 0.933 0.001
E72.0 Disorders of amino-acid transport
0.066 0.933 0.001
E75.6 Lipid storage disorder, unspecified
0.066 0.933 0.001
E75.5 Other lipid storage disorders
0.066 0.933 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.066 0.933 0.001
E75.3 Sphingolipidosis, unspecified
0.066 0.933 0.001
E75.2 Other sphingolipidosis
0.066 0.933 0.001
E75.1 Other gangliosidosis
0.066 0.933 0.001
E75.0 GM2 gangliosidosis
0.066 0.933 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.066 0.933 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.066 0.933 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.066 0.933 0.001
E76.2 Other mucopolysaccharidoses
0.066 0.933 0.001
E76.1 Mucopolysaccharidosis, type II
0.066 0.933 0.001
E76.0 Mucopolysaccharidosis, type I
0.066 0.933 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.066 0.933 0.001
E77.8 Other disorders of glycoprotein metabolism
0.066 0.933 0.001
E77.1 Defects in glycoprotein degradation
0.066 0.933 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.066 0.933 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.066 0.933 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.066 0.933 0.001
E79.1 Lesch-Nyhan syndrome
0.066 0.933 0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.066 0.933 0.001
E84.9 Cystic fibrosis, unspecified
0.066 0.933 0.001
E84.8 Cystic fibrosis with other manifestations
0.066 0.933 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.066 0.933 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.066 0.933 0.001
I20.0 Unstable angina
0.067 0.933 0.000
E66 Obesity
0.065 0.934 0.001
I22 Subsequent myocardial infarction
0.066 0.934 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.065 0.935 0.001
E89.8 Other postprocedural endocrine and metabolic disorders
0.065 0.935 0.001
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.065 0.935 0.001
E89.5 Postprocedural testicular hypofunction
0.065 0.935 0.001
E89.4 Postprocedural ovarian failure
0.065 0.935 0.001
E89.1 Postprocedural hypoinsulinaemia
0.065 0.935 0.001
I25.1 Atherosclerotic heart disease
0.065 0.935 0.000
E04.1 Non-toxic single thyroid nodule
0.064 0.935 0.000
E04.9 Non-toxic goitre, unspecified
0.064 0.936 0.000
E85.9 Amyloidosis, unspecified
0.063 0.936 0.001
E85.8 Other amyloidosis
0.063 0.936 0.001
E85.3 Secondary systemic amyloidosis
0.063 0.936 0.001
E85.2 Heredofamilial amyloidosis, unspecified
0.063 0.936 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.063 0.936 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.063 0.936 0.001
J43.9 Emphysema, unspecified
0.004 0.937 0.058
E61 Deficiency of other nutrient elements
0.060 0.937 0.003
E04.2 Non-toxic multinodular goitre
0.062 0.937 0.000
I25 Chronic ischaemic heart disease
0.063 0.937 0.000
E11 Non-insulin-dependent diabetes mellitus
0.001 0.940 0.060
I21.X Presumed acute myicardial infaction (unconfirmed)
0.060 0.940 0.000
E85.4 Organ-limited amyloidosis
0.059 0.940 0.001
E66.8 Other obesity
0.059 0.941 0.000
E73.8 Other lactose intolerance
0.058 0.941 0.001
E73.1 Secondary lactase deficiency
0.058 0.941 0.001
E73.0 Congenital lactase deficiency
0.058 0.941 0.001
I22.1 Subsequent myocardial infarction of inferior wall
0.058 0.942 0.000
E15 Nondiabetic hypoglycaemic coma
0.054 0.942 0.004
E64 Sequelae of malnutrition and other nutritional deficiencies
0.054 0.943 0.003
E63 Other nutritional deficiencies
0.054 0.943 0.003
E56 Other vitamin deficiencies
0.054 0.943 0.003
E51 Thiamine deficiency
0.054 0.943 0.003
E50 Vitamin A deficiency
0.054 0.943 0.003
E60 Dietary zinc deficiency
0.054 0.943 0.003
E59 Dietary selenium deficiency
0.054 0.943 0.003
E58 Dietary calcium deficiency
0.054 0.943 0.003
E54 Ascorbic acid deficiency
0.054 0.943 0.003
E52 Niacin deficiency [pellagra]
0.054 0.943 0.003
I23 Certain current complications following acute myocardial infarction
0.057 0.943 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.057 0.943 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.056 0.944 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.944 0.056
I21.3 Acute transmural myocardial infarction of unspecified site
0.056 0.944 0.000
D50.8 Other iron deficiency anaemias
0.000 0.946 0.054
E89.3 Postprocedural hypopituitarism
0.053 0.946 0.001
E44.1 Mild protein-energy malnutrition
0.051 0.946 0.002
E44.0 Moderate protein-energy malnutrition
0.051 0.946 0.002
I20.1 Angina pectoris with documented spasm
0.053 0.947 0.000
E67.8 Other specified hyperalimentation
0.052 0.947 0.002
E67.3 Hypervitaminosis D
0.052 0.947 0.002
E67.2 Megavitamin-B6 syndrome
0.052 0.947 0.002
E67.1 Hypercarotenaemia
0.052 0.947 0.002
E67.0 Hypervitaminosis A
0.052 0.947 0.002
E11.4 With neurological complications
0.000 0.947 0.053
E05.9 Thyrotoxicosis, unspecified
0.053 0.947 0.000
E11.1 With ketoacidosis
0.000 0.948 0.052
D51 Vitamin B12 deficiency anaemia
0.000 0.948 0.051
I25.3 Aneurysm of heart
0.051 0.949 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.050 0.950 0.000
E61.2 Magnesium deficiency
0.048 0.950 0.002
E88.9 Metabolic disorder, unspecified
0.048 0.951 0.001
E88.8 Other specified metabolic disorders
0.048 0.951 0.001
E88.3 Tumour lysis syndrome
0.048 0.951 0.001
E88.2 Lipomatosis, not elsewhere classified
0.048 0.951 0.001
E88.1 Lipodystrophy, not elsewhere classified
0.048 0.951 0.001
T91 Sequelae of injuries of neck and trunk
0.049 0.951 0.000
E11.5 With peripheral circulatory complications
0.000 0.952 0.048
E66.2 Extreme obesity with alveolar hypoventilation
0.047 0.952 0.001
E66.1 Drug-induced obesity
0.047 0.952 0.001
E66.0 Obesity due to excess calories
0.047 0.952 0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.048 0.952 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.048 0.952 0.000
D50-D53 Nutritional anaemias
0.001 0.953 0.046
E73.9 Lactose intolerance, unspecified
0.046 0.953 0.001
E61.1 Iron deficiency
0.046 0.953 0.001
D50 Iron deficiency anaemia
0.000 0.953 0.047
E55 Vitamin D deficiency
0.044 0.953 0.004
T36-T50 Poisoning by drugs, medicaments and biological substances
0.047 0.953 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.046 0.954 0.000
T42.4 Benzodiazepines
0.045 0.955 0.000
E61.9 Deficiency of nutrient element, unspecified
0.043 0.955 0.002
E61.8 Deficiency of other specified nutrient elements
0.043 0.955 0.002
E61.7 Deficiency of multiple nutrient elements
0.043 0.955 0.002
E61.6 Vanadium deficiency
0.043 0.955 0.002
E61.5 Molybdenum deficiency
0.043 0.955 0.002
E61.4 Chromium deficiency
0.043 0.955 0.002
E61.3 Manganese deficiency
0.043 0.955 0.002
E61.0 Copper deficiency
0.043 0.955 0.002
I25.6 Silent myocardial ischaemia
0.045 0.955 0.000
I25.4 Coronary artery aneurysm
0.045 0.955 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.045 0.955 0.000
I22.8 Subsequent myocardial infarction of other sites
0.044 0.956 0.000
I25.5 Ischaemic cardiomyopathy
0.044 0.956 0.000
T91.3 Sequelae of injury of spinal cord
0.044 0.956 0.000
E11.7 With multiple complications
0.001 0.956 0.043
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.044 0.956 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.043 0.957 0.000
E20-E35 Disorders of other endocrine glands
0.037 0.957 0.006
E11.8 With unspecified complications
0.001 0.957 0.042
I23.8 Other current complications following acute myocardial infarction
0.043 0.957 0.000
I20.8 Other forms of angina pectoris
0.042 0.958 0.000
T91.1 Sequelae of fracture of spine
0.042 0.958 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.958 0.042
E53 Deficiency of other B group vitamins
0.038 0.958 0.004
E86 Volume depletion
0.041 0.959 0.000
T90 Sequelae of injuries of head
0.041 0.959 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.041 0.959 0.000
E50.9 Vitamin A deficiency, unspecified
0.039 0.959 0.003
E50.8 Other manifestations of vitamin A deficiency
0.039 0.959 0.003
E50.7 Other ocular manifestations of vitamin A deficiency
0.039 0.959 0.003
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.039 0.959 0.003
E50.5 Vitamin A deficiency with night blindness
0.039 0.959 0.003
E50.4 Vitamin A deficiency with keratomalacia
0.039 0.959 0.003
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.039 0.959 0.003
E50.2 Vitamin A deficiency with corneal xerosis
0.039 0.959 0.003
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.039 0.959 0.003
E50.0 Vitamin A deficiency with conjunctival xerosis
0.039 0.959 0.003
E51.9 Thiamine deficiency, unspecified
0.039 0.959 0.003
E51.8 Other manifestations of thiamine deficiency
0.039 0.959 0.003
E51.2 Wernicke's encephalopathy
0.039 0.959 0.003
E51.1 Beriberi
0.039 0.959 0.003
E56.9 Vitamin deficiency, unspecified
0.039 0.959 0.003
E56.8 Deficiency of other vitamins
0.039 0.959 0.003
E56.1 Deficiency of vitamin K
0.039 0.959 0.003
E56.0 Deficiency of vitamin E
0.039 0.959 0.003
E63.9 Nutritional deficiency, unspecified
0.039 0.959 0.003
E63.8 Other specified nutritional deficiencies
0.039 0.959 0.003
E63.1 Imbalance of constituents of food intake
0.039 0.959 0.003
E63.0 Essential fatty acid [EFA] deficiency
0.039 0.959 0.003
E64.9 Sequelae of unspecified nutritional deficiency
0.039 0.959 0.003
E64.8 Sequelae of other nutritional deficiencies
0.039 0.959 0.003
E64.3 Sequelae of rickets
0.039 0.959 0.003
E64.2 Sequelae of vitamin C deficiency
0.039 0.959 0.003
E64.1 Sequelae of vitamin A deficiency
0.039 0.959 0.003
E64.0 Sequelae of protein-energy malnutrition
0.039 0.959 0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.041 0.959 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.041 0.959 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.041 0.959 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.041 0.959 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.041 0.959 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.041 0.959 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.041 0.959 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.041 0.959 0.000
E16 Other disorders of pancreatic internal secretion
0.037 0.959 0.004
T50.9 Other and unspecified drugs, medicaments and biological substances
0.041 0.959 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.041 0.959 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.039 0.960 0.001
T93 Sequelae of injuries of lower limb
0.040 0.960 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.039 0.961 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.039 0.961 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.038 0.961 0.000
S40-S49 Injuries to the shoulder and upper arm
0.038 0.962 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.037 0.963 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.963 0.037
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.963 0.037
D51.2 Transcobalamin II deficiency
0.000 0.963 0.037
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.963 0.037
E11.6 With other specified complications
0.001 0.963 0.036
E11.2 With renal complications
0.001 0.963 0.036
E78.5 Hyperlipidaemia, unspecified
0.036 0.964 0.000
T79-T79 Certain early complications of trauma
0.036 0.964 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.036 0.964 0.000
T42.1 Iminostilbenes
0.036 0.964 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.035 0.965 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.035 0.965 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.035 0.965 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.035 0.965 0.000
E11.0 With coma
0.001 0.965 0.034
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.035 0.965 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.034 0.966 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.034 0.966 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.034 0.966 0.000
T42.3 Barbiturates
0.034 0.966 0.000
T42.2 Succinimides and oxazolidinediones
0.034 0.966 0.000
T42.0 Hydantoin derivatives
0.034 0.966 0.000
T95 Sequelae of burns, corrosions and frostbite
0.034 0.966 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.034 0.966 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.034 0.966 0.000
D53 Other nutritional anaemias
0.001 0.966 0.033
D50.1 Sideropenic dysphagia
0.000 0.966 0.034
E55.0 Rickets, active
0.031 0.966 0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.034 0.966 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.034 0.966 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.034 0.966 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.034 0.966 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.034 0.966 0.000
T36 Poisoning by systemic antibiotics
0.034 0.966 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.031 0.966 0.003
I24 Other acute ischaemic heart diseases
0.033 0.967 0.000
T90.5 Sequelae of intracranial injury
0.033 0.967 0.000
T92 Sequelae of injuries of upper limb
0.033 0.967 0.000
E26 Hyperaldosteronism
0.029 0.967 0.004
T98 Sequelae of other and unspecified effects of external causes
0.033 0.967 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.033 0.967 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.032 0.967 0.000
T90.4 Sequelae of injury of eye and orbit
0.032 0.968 0.000
S10-S19 Injuries to the neck
0.032 0.968 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.032 0.968 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.032 0.968 0.000
T43.2 Other and unspecified antidepressants
0.032 0.968 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.032 0.968 0.000
T94.1 Sequelae of injuries, not specified by body region
0.032 0.968 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.032 0.968 0.000
T90.8 Sequelae of other specified injuries of head
0.032 0.968 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.032 0.968 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.032 0.968 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.031 0.968 0.000
S40 Superficial injury of shoulder and upper arm
0.031 0.969 0.000
T50.8 Diagnostic agents
0.031 0.969 0.000
T50.7 Analeptics and opioid receptor antagonists
0.031 0.969 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.031 0.969 0.000
T50.5 Appetite depressants
0.031 0.969 0.000
T50.4 Drugs affecting uric acid metabolism
0.031 0.969 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.031 0.969 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.031 0.969 0.000
T50.1 Loop [high-ceiling] diuretics
0.031 0.969 0.000
T50.0 Mineralocorticoids and their antagonists
0.031 0.969 0.000
S50-S59 Injuries to the elbow and forearm
0.031 0.969 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.027 0.969 0.004
E32 Diseases of thymus
0.027 0.969 0.004
E31 Polyglandular dysfunction
0.027 0.969 0.004
E30 Disorders of puberty, not elsewhere classified
0.027 0.969 0.004
E25 Adrenogenital disorders
0.027 0.969 0.004
E20 Hypoparathyroidism
0.027 0.969 0.004
T90.9 Sequelae of unspecified injury of head
0.031 0.969 0.000
D52 Folate deficiency anaemia
0.001 0.969 0.030
I21.4 Acute subendocardial myocardial infarction
0.030 0.969 0.000
T45.0 Antiallergic and antiemetic drugs
0.030 0.969 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.030 0.970 0.000
E53.9 Vitamin B deficiency, unspecified
0.028 0.970 0.003
E53.1 Pyridoxine deficiency
0.028 0.970 0.003
E53.0 Riboflavin deficiency
0.028 0.970 0.003
S42 Fracture of shoulder and upper arm
0.030 0.970 0.000
T59 Toxic effect of other gases, fumes and vapours
0.030 0.970 0.000
D50.9 Iron deficiency anaemia, unspecified
0.000 0.970 0.030
J44 Other chronic obstructive pulmonary disease
0.024 0.970 0.006
T90.3 Sequelae of injury of cranial nerves
0.030 0.970 0.000
T90.1 Sequelae of open wound of head
0.030 0.970 0.000
T90.0 Sequelae of superficial injury of head
0.030 0.970 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.030 0.970 0.000
T33-T35 Frostbite
0.030 0.970 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.030 0.970 0.000
T00-T07 Injuries involving multiple body regions
0.030 0.970 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.030 0.970 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.027 0.970 0.003
E16.8 Other specified disorders of pancreatic internal secretion
0.027 0.970 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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