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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2075582
log Bayes Factor = 79.4434
Chromosome 6   position 31,497,706  (GRCh37) Explore rs2075582 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.001 0.999
Chapter IX Diseases of the circulatory system
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
# Top node
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
E14.9 Without complications
0.000 0.003 0.997
K90-K93 Other diseases of the digestive system
0.000 0.003 0.997
K70-K77 Diseases of liver
0.000 0.006 0.994
I25.1 Atherosclerotic heart disease
0.000 0.006 0.994
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.006 0.994
E10.1 With ketoacidosis
0.000 0.006 0.994
Chapter VIII Diseases of the ear and mastoid process
0.000 0.007 0.993
G35-G37 Demyelinating diseases of the central nervous system
0.990 0.010 0.000
G37 Other demyelinating diseases of central nervous system
0.988 0.012 0.000
E10.4 With neurological complications
0.000 0.013 0.987
K74 Fibrosis and cirrhosis of liver
0.000 0.014 0.986
H36.0 Diabetic retinopathy
0.000 0.015 0.985
L40.5 Arthropathic psoriasis
0.000 0.016 0.984
G37.9 Demyelinating disease of central nervous system, unspecified
0.984 0.016 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.017 0.983
H30-H36 Disorders of choroid and retina
0.000 0.018 0.982
H65-H75 Diseases of middle ear and mastoid
0.000 0.026 0.974
Chapter VII Diseases of the eye and adnexa
0.000 0.026 0.974
H35 Other retinal disorders
0.000 0.028 0.972
E78.0 Pure hypercholesterolaemia
0.000 0.033 0.967
H60-H62 Diseases of external ear
0.000 0.033 0.967
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.036 0.964
I22 Subsequent myocardial infarction
0.000 0.037 0.963
H35.8 Other specified retinal disorders
0.000 0.038 0.962
E70-E90 Metabolic disorders
0.000 0.040 0.960
I24 Other acute ischaemic heart diseases
0.000 0.040 0.960
K74.6 Other and unspecified cirrhosis of liver
0.000 0.042 0.958
I25.5 Ischaemic cardiomyopathy
0.000 0.044 0.956
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.047 0.953
H66 Suppurative and unspecified otitis media
0.000 0.049 0.951
H66.3 Other chronic suppurative otitis media
0.000 0.054 0.946
L43 Lichen planus
0.000 0.059 0.941
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.062 0.938
H71 Cholesteatoma of middle ear
0.000 0.062 0.938
E00-E07 Disorders of thyroid gland
0.000 0.063 0.937
K60.2 Anal fissure, unspecified
0.000 0.069 0.931
K60 Fissure and fistula of anal and rectal regions
0.000 0.077 0.923
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.078 0.922
E03 Other hypothyroidism
0.000 0.079 0.921
I24.8 Other forms of acute ischaemic heart disease
0.000 0.079 0.921
K55-K64 Other diseases of intestines
0.000 0.082 0.918
E03.9 Hypothyroidism, unspecified
0.000 0.085 0.915
E13 Other specified diabetes mellitus
0.000 0.087 0.913
K74.5 Biliary cirrhosis, unspecified
0.000 0.098 0.902
H60 Otitis externa
0.000 0.102 0.898
H61 Other disorders of external ear
0.000 0.104 0.896
E16 Other disorders of pancreatic internal secretion
0.000 0.106 0.894
E10.8 With unspecified complications
0.000 0.114 0.886
K58 Irritable bowel syndrome
0.000 0.118 0.882
E10.5 With peripheral circulatory complications
0.000 0.119 0.881
E78.8 Other disorders of lipoprotein metabolism
0.000 0.119 0.881
G37.8 Other specified demyelinating diseases of central nervous system
0.877 0.123 0.000
I25.2 Old myocardial infarction
0.000 0.125 0.875
L43.9 Lichen planus, unspecified
0.000 0.126 0.874
E10.2 With renal complications
0.000 0.128 0.872
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.132 0.868
L50-L54 Urticaria and erythema
0.000 0.136 0.864
E10.0 With coma
0.000 0.141 0.859
K75 Other inflammatory liver diseases
0.000 0.141 0.859
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.142 0.858
E11.6 With other specified complications
0.000 0.142 0.858
K76 Other diseases of liver
0.000 0.143 0.857
H53-H54 Visual disturbances and blindness
0.000 0.143 0.857
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.146 0.854
E13.9 Without complications
0.000 0.149 0.851
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.150 0.850
E16.2 Hypoglycaemia, unspecified
0.000 0.153 0.847
E11.0 With coma
0.000 0.157 0.843
K50-K52 Noninfective enteritis and colitis
0.000 0.160 0.840
I15 Secondary hypertension
0.000 0.160 0.840
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.161 0.839
H35.2 Other proliferative retinopathy
0.000 0.167 0.833
E78.2 Mixed hyperlipidaemia
0.000 0.172 0.828
K73 Chronic hepatitis, not elsewhere classified
0.000 0.173 0.827
K52 Other non-infective gastro-enteritis and colitis
0.000 0.173 0.827
K74.3 Primary biliary cirrhosis
0.000 0.176 0.824
K60.0 Acute anal fissure
0.000 0.176 0.824
I20 Angina pectoris
0.000 0.177 0.823
E11.3 With ophthalmic complications
0.000 0.179 0.821
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.183 0.817
I11 Hypertensive heart disease
0.000 0.187 0.813
E11.1 With ketoacidosis
0.000 0.189 0.811
E14.8 With unspecified complications
0.000 0.189 0.811
I20.9 Angina pectoris, unspecified
0.000 0.193 0.807
K76.9 Liver disease, unspecified
0.000 0.196 0.804
K86 Other diseases of pancreas
0.000 0.201 0.799
H61.1 Non-infective disorders of pinna
0.000 0.202 0.798
L40.8 Other psoriasis
0.000 0.206 0.794
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.209 0.791
L40.1 Generalised pustular psoriasis
0.000 0.209 0.791
K83 Other diseases of biliary tract
0.000 0.212 0.788
K75.4 Autoimmune hepatitis
0.000 0.216 0.784
H61.3 Acquired stenosis of external ear canal
0.000 0.218 0.782
E10.6 With other specified complications
0.000 0.219 0.781
L42 Pityriasis rosea
0.000 0.220 0.780
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.222 0.778
E14.6 With other specified complications
0.000 0.222 0.778
K60.5 Anorectal fistula
0.000 0.222 0.778
K83.0 Cholangitis
0.000 0.222 0.778
I23 Certain current complications following acute myocardial infarction
0.000 0.223 0.777
L43.8 Other lichen planus
0.000 0.225 0.775
E11.2 With renal complications
0.000 0.225 0.775
J45 Asthma
0.000 0.226 0.774
H35.0 Background retinopathy and retinal vascular changes
0.000 0.227 0.773
H35.5 Hereditary retinal dystrophy
0.000 0.229 0.771
H60.3 Other infective otitis externa
0.000 0.230 0.770
H54 Blindness and low vision
0.000 0.232 0.768
E74 Other disorders of carbohydrate metabolism
0.000 0.233 0.767
H35.7 Separation of retinal layers
0.000 0.236 0.764
H74 Other disorders of middle ear and mastoid
0.000 0.244 0.756
K86.1 Other chronic pancreatitis
0.000 0.249 0.751
E14.1 With ketoacidosis
0.000 0.250 0.750
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.748 0.252 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.254 0.746
E78.6 Lipoprotein deficiency
0.000 0.254 0.746
K90.8 Other intestinal malabsorption
0.000 0.257 0.743
H54.9 Unspecified visual impairment (binocular)
0.000 0.257 0.743
E11.4 With neurological complications
0.000 0.258 0.742
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.738
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.263 0.737
H34 Retinal vascular occlusions
0.000 0.264 0.736
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.265 0.735
E05.9 Thyrotoxicosis, unspecified
0.000 0.266 0.734
H61.2 Impacted cerumen
0.000 0.274 0.726
H61.9 Disorder of external ear, unspecified
0.000 0.275 0.725
E16.1 Other hypoglycaemia
0.000 0.279 0.721
K73.9 Chronic hepatitis, unspecified
0.000 0.279 0.721
E14.4 With neurological complications
0.000 0.280 0.720
L52 Erythema nodosum
0.000 0.280 0.720
L10-L14 Bullous disorders
0.000 0.281 0.719
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.281 0.719
K52.1 Toxic gastro-enteritis and colitis
0.000 0.281 0.719
H35.6 Retinal haemorrhage
0.000 0.282 0.718
G36 Other acute disseminated demyelination
0.718 0.282 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.716
I00-I02 Acute rheumatic fever
0.000 0.283 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.716
K75.8 Other specified inflammatory liver diseases
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
H31 Other disorders of choroid
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.715
K90.1 Tropical sprue
0.000 0.284 0.715
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.285 0.715
K60.4 Rectal fistula
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.285 0.715
E85 Amyloidosis
0.000 0.286 0.714
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
I25.3 Aneurysm of heart
0.000 0.287 0.712
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.288 0.712
H72 Perforation of tympanic membrane
0.000 0.289 0.711
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.290 0.710
H60.9 Otitis externa, unspecified
0.000 0.291 0.709
K71 Toxic liver disease
0.000 0.291 0.709
G37.5 Concentric sclerosis [Balo]
0.708 0.292 0.000
G37.4 Subacute necrotising myelitis
0.708 0.292 0.000
G37.2 Central pontine myelinolysis
0.708 0.292 0.000
G37.1 Central demyelination of corpus callosum
0.708 0.292 0.000
G37.0 Diffuse sclerosis
0.708 0.292 0.000
E88 Other metabolic disorders
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.000 0.293 0.707
H66.4 Suppurative otitis media, unspecified
0.000 0.293 0.707
K74.4 Secondary biliary cirrhosis
0.000 0.293 0.707
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.293 0.707
K74.1 Hepatic sclerosis
0.000 0.293 0.707
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.295 0.705
K86.2 Cyst of pancreas
0.000 0.296 0.704
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.296 0.704
I15.1 Hypertension secondary to other renal disorders
0.000 0.296 0.704
H60.5 Acute otitis externa, non-infective
0.000 0.298 0.701
J40-J47 Chronic lower respiratory diseases
0.000 0.299 0.701
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.302 0.698
H68 Eustachian salpingitis and obstruction
0.000 0.302 0.698
H67 Otitis media in diseases classified elsewhere
0.000 0.302 0.698
H43-H45 Disorders of vitreous body and globe
0.000 0.302 0.698
I25.4 Coronary artery aneurysm
0.000 0.303 0.697
H35.1 Retinopathy of prematurity
0.000 0.303 0.697
Chapter X Diseases of the respiratory system
0.000 0.305 0.695
H70 Mastoiditis and related conditions
0.000 0.306 0.694
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.306 0.693
E79 Disorders of purine and pyrimidine metabolism
0.000 0.309 0.691
E78.3 Hyperchylomicronaemia
0.000 0.309 0.691
H90-H95 Other disorders of ear
0.000 0.309 0.691
E77 Disorders of glycoprotein metabolism
0.000 0.311 0.688
E76 Disorders of glycosaminoglycan metabolism
0.000 0.311 0.688
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.311 0.688
E70 Disorders of aromatic amino-acid metabolism
0.000 0.311 0.688
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.311 0.688
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.317 0.683
H60.4 Cholesteatoma of external ear
0.000 0.320 0.680
K76.8 Other specified diseases of liver
0.000 0.322 0.678
H60.1 Cellulitis of external ear
0.000 0.322 0.678
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.324 0.676
H30 Chorioretinal inflammation
0.000 0.324 0.675
H35.4 Peripheral retinal degeneration
0.000 0.325 0.675
L43.3 Subacute (active) lichen planus
0.000 0.325 0.675
L43.2 Lichenoid drug reaction
0.000 0.325 0.675
L43.1 Bullous lichen planus
0.000 0.325 0.675
L43.0 Hypertrophic lichen planus
0.000 0.325 0.675
L51 Erythema multiforme
0.000 0.326 0.674
H66.0 Acute suppurative otitis media
0.000 0.327 0.673
E15 Nondiabetic hypoglycaemic coma
0.000 0.327 0.673
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.328 0.671
E00 Congenital iodine-deficiency syndrome
0.000 0.328 0.671
K90.9 Intestinal malabsorption, unspecified
0.000 0.330 0.670
H54.7 Unspecified visual loss
0.000 0.330 0.670
L50 Urticaria
0.000 0.332 0.668
E03.5 Myxoedema coma
0.000 0.339 0.661
E03.4 Atrophy of thyroid (acquired)
0.000 0.339 0.661
E03.3 Postinfectious hypothyroidism
0.000 0.339 0.661
E03.1 Congenital hypothyroidism without goitre
0.000 0.339 0.661
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.339 0.661
H60.8 Other otitis externa
0.000 0.340 0.660
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.342 0.658
H55-H59 Other disorders of eye and adnexa
0.000 0.342 0.658
E72 Other disorders of amino-acid metabolism
0.000 0.344 0.656
E13.8 With unspecified complications
0.000 0.345 0.655
E13.7 With multiple complications
0.000 0.345 0.655
E13.6 With other specified complications
0.000 0.345 0.655
E13.5 With peripheral circulatory complications
0.000 0.345 0.655
E13.4 With neurological complications
0.000 0.345 0.655
E13.3 With ophthalmic complications
0.000 0.345 0.655
E13.2 With renal complications
0.000 0.345 0.655
E13.1 With ketoacidosis
0.000 0.345 0.655
E13.0 With coma
0.000 0.345 0.655
E78.1 Pure hyperglyceridaemia
0.000 0.346 0.654
E83.1 Disorders of iron metabolism
0.649 0.351 0.000
K81 Cholecystitis
0.000 0.351 0.649
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.352 0.648
H74.4 Polyp of middle ear
0.000 0.352 0.648
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.352 0.647
I12 Hypertensive renal disease
0.000 0.353 0.647
H60.0 Abscess of external ear
0.000 0.353 0.647
E84 Cystic fibrosis
0.000 0.355 0.644
K58.9 Irritable bowel syndrome without diarrhoea
0.000 0.356 0.644
H60.2 Malignant otitis externa
0.000 0.356 0.644
K74.0 Hepatic fibrosis
0.000 0.357 0.643
K86.3 Pseudocyst of pancreas
0.000 0.358 0.642
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.359 0.641
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.359 0.641
E16.4 Abnormal secretion of gastrin
0.000 0.359 0.641
E16.3 Increased secretion of glucagon
0.000 0.359 0.641
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.359 0.641
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.362 0.638
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.363 0.637
H35.9 Retinal disorder, unspecified
0.000 0.364 0.636
E11.5 With peripheral circulatory complications
0.000 0.364 0.636
H73 Other disorders of tympanic membrane
0.000 0.366 0.634
L40.0 Psoriasis vulgaris
0.000 0.366 0.633
E07 Other disorders of thyroid
0.000 0.367 0.632
J43 Emphysema
0.000 0.369 0.631
H53 Visual disturbances
0.000 0.371 0.629
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.372 0.628
I15.9 Seconday hypertension, unspecified
0.000 0.375 0.625
E40-E46 Malnutrition
0.000 0.376 0.624
I15.0 Renovascular hypertension
0.000 0.378 0.622
H90 Conductive and sensorineural hearing loss
0.000 0.379 0.621
L54 Erythema in diseases classified elsewhere
0.000 0.380 0.619
E88.2 Lipomatosis, not elsewhere classified
0.000 0.383 0.617
I23.8 Other current complications following acute myocardial infarction
0.000 0.383 0.617
K75.2 Nonspecific reactive hepatitis
0.000 0.384 0.616
K75.1 Phlebitis of portal vein
0.000 0.384 0.616
H34.8 Other retinal vascular occlusions
0.000 0.385 0.615
K76.5 Hepatic veno-occlusive disease
0.000 0.385 0.614
K76.4 Peliosis hepatis
0.000 0.385 0.614
K76.3 Infarction of liver
0.000 0.385 0.614
K76.2 Central haemorrhagic necrosis of liver
0.000 0.385 0.614
L53 Other erythematous conditions
0.000 0.388 0.612
E78.4 Other hyperlipidaemia
0.000 0.389 0.611
H72.0 Central perforation of tympanic membrane
0.000 0.390 0.610
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.390 0.610
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.393 0.607
I15.8 Other secondary hypertension
0.000 0.397 0.602
I15.2 Hypertension secondary to endocrine disorders
0.000 0.397 0.602
K55 Vascular disorders of intestine
0.000 0.398 0.602
E05.5 Thyroid crisis or storm
0.000 0.398 0.602
E05.4 Thyrotoxicosis factitia
0.000 0.398 0.602
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.398 0.602
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.398 0.602
I24.1 Dressler's syndrome
0.000 0.399 0.601
K83.3 Fistula of bile duct
0.000 0.399 0.601
K72.9 Hepatic failure, unspecified
0.000 0.399 0.601
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.403 0.596
L13 Other bullous disorders
0.000 0.405 0.595
K81.1 Chronic cholecystitis
0.000 0.406 0.594
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.407 0.593
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.407 0.593
E50-E64 Other nutritional deficiencies
0.000 0.407 0.593
H43 Disorders of vitreous body
0.000 0.409 0.591
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.409 0.590
H72.2 Other marginal perforations of tympanic membrane
0.000 0.412 0.588
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.413 0.587
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.415 0.585
E83 Disorders of mineral metabolism
0.555 0.417 0.028
H90.5 Sensorineural hearing loss, unspecified
0.000 0.421 0.578
H55 Nystagmus and other irregular eye movements
0.000 0.423 0.577
E85.9 Amyloidosis, unspecified
0.000 0.424 0.576
I22.8 Subsequent myocardial infarction of other sites
0.000 0.425 0.574
H53.1 Subjective visual disturbances
0.000 0.427 0.573
H47.3 Other disorders of optic disk
0.000 0.428 0.572
E78.5 Hyperlipidaemia, unspecified
0.000 0.430 0.570
J60-J70 Lung diseases due to external agents
0.000 0.434 0.566
K83.5 Biliary cyst
0.000 0.435 0.565
K83.2 Perforation of bile duct
0.000 0.435 0.565
K81.9 Cholecystitis, unspecified
0.000 0.437 0.563
H92 Otalgia and effusion of ear
0.000 0.437 0.563
H72.8 Other perforations of tympanic membrane
0.000 0.438 0.562
E06 Thyroiditis
0.000 0.440 0.560
K83.4 Spasm of sphincter of Oddi
0.000 0.441 0.559
J43.9 Emphysema, unspecified
0.000 0.442 0.558
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.443 0.557
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.443 0.557
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.443 0.557
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.557
J45.1 Nonallergic asthma
0.000 0.445 0.555
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.445 0.555
J46 Status asthmaticus
0.000 0.449 0.551
E89.3 Postprocedural hypopituitarism
0.000 0.449 0.551
H54.3 Unqualified visual loss, both eyes
0.000 0.450 0.550
H54.2 Low vision, both eyes
0.000 0.450 0.550
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.450 0.550
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.450 0.550
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.450 0.550
E74.2 Disorders of galactose metabolism
0.000 0.450 0.550
E74.1 Disorders of fructose metabolism
0.000 0.450 0.550
E74.0 Glycogen storage disease
0.000 0.450 0.550
J42 Unspecified chronic bronchitis
0.000 0.450 0.550
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.451 0.549
H54.0 Blindness, both eyes
0.000 0.452 0.548
H31.1 Choroidal degeneration
0.000 0.453 0.547
H31.0 Chorioretinal scars
0.000 0.454 0.546
K83.9 Disease of biliary tract, unspecified
0.000 0.455 0.545
K55.8 Other vascular disorders of intestine
0.000 0.456 0.544
I12.9 Hypertensive renal disease without renal failure
0.000 0.456 0.544
E83.3 Disorders of phosphorus metabolism
0.539 0.457 0.004
H53.8 Other visual disturbances
0.000 0.457 0.543
H61.8 Other specified disorders of external ear
0.000 0.458 0.542
E88.3 Tumour lysis syndrome
0.000 0.460 0.540
K75.0 Abscess of liver
0.000 0.460 0.540
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.461 0.539
K76.7 Hepatorenal syndrome
0.000 0.462 0.538
I20.0 Unstable angina
0.000 0.464 0.536
K72.1 Chronic hepatic failure
0.000 0.465 0.535
E75.5 Other lipid storage disorders
0.000 0.465 0.534
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.468 0.532
E73 Lactose intolerance
0.001 0.468 0.532
K76.1 Chronic passive congestion of liver
0.000 0.469 0.530
H34.9 Retinal vascular occlusion, unspecified
0.000 0.470 0.530
K75.9 Inflammatory liver disease, unspecified
0.000 0.470 0.530
H53.0 Amblyopia ex anopsia
0.000 0.472 0.528
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.472 0.528
H34.0 Transient retinal artery occlusion
0.000 0.472 0.528
G36.0 Neuromyelitis optica [Devic]
0.523 0.477 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.477 0.523
L50.9 Urticaria, unspecified
0.000 0.479 0.521
H70.1 Chronic mastoiditis
0.000 0.479 0.520
L51.1 Bullous erythema multiforme
0.000 0.480 0.520
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.481 0.518
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.482 0.518
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.482 0.518
J69 Pneumonitis due to solids and liquids
0.000 0.482 0.518
L10 Pemphigus
0.000 0.485 0.515
L14 Bullous disorders in diseases classified elsewhere
0.000 0.485 0.515
H10-H13 Disorders of conjunctiva
0.000 0.485 0.515
H47.2 Optic atrophy
0.000 0.485 0.515
G36.9 Acute disseminated demyelination, unspecified
0.515 0.485 0.000
G36.8 Other specified acute disseminated demyelination
0.515 0.485 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.515 0.485 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
J90-J94 Other diseases of pleura
0.000 0.486 0.514
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.486 0.514
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.486 0.514
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.486 0.514
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.486 0.514
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
P90-P96 Other disorders originating in the perinatal period
0.000 0.486 0.514
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.486 0.514
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.486 0.514
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.486 0.514
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.486 0.514
P35-P39 Infections specific to the perinatal period
0.000 0.486 0.514
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.486 0.514
P10-P15 Birth trauma
0.000 0.486 0.514
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.486 0.514
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.486 0.514
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.513
L41.8 Other parapsoriasis
0.000 0.486 0.513
L41.5 Retiform parapsoriasis
0.000 0.486 0.513
L41.4 Large plaque parapsoriasis
0.000 0.486 0.513
L41.3 Small plaque parapsoriasis
0.000 0.486 0.513
L41.2 Lymphomatoid papulosis
0.000 0.486 0.513
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.513
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.513
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.513
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.513
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.513
L44.3 Lichen ruber moniliformis
0.000 0.486 0.513
L44.2 Lichen striatus
0.000 0.486 0.513
L44.1 Lichen nitidus
0.000 0.486 0.513
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.513
H31.9 Disorder of choroid, unspecified
0.000 0.486 0.513
H31.4 Choroidal detachment
0.000 0.486 0.513
H31.2 Hereditary choroidal dystrophy
0.000 0.486 0.513
H92.1 Otorrhoea
0.000 0.487 0.513
E85.3 Secondary systemic amyloidosis
0.000 0.487 0.513
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.487 0.512
K93.1 Megacolon in Chagas' disease
0.000 0.487 0.512
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.487 0.512
E85.8 Other amyloidosis
0.000 0.488 0.512
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.488 0.512
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.488 0.512
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.488 0.512
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.488 0.512
K80 Cholelithiasis
0.000 0.488 0.512
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.489 0.511
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
E88.8 Other specified metabolic disorders
0.000 0.489 0.511
E75.6 Lipid storage disorder, unspecified
0.000 0.489 0.511
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.489 0.511
E75.3 Sphingolipidosis, unspecified
0.000 0.489 0.511
E75.2 Other sphingolipidosis
0.000 0.489 0.511
E75.1 Other gangliosidosis
0.000 0.489 0.511
E75.0 GM2 gangliosidosis
0.000 0.489 0.511
K71.9 Toxic liver disease, unspecified
0.000 0.491 0.508
K71.8 Toxic liver disease with other disorders of liver
0.000 0.491 0.508
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.491 0.508
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.491 0.508
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.491 0.508
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.491 0.508
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.491 0.508
K71.2 Toxic liver disease with acute hepatitis
0.000 0.491 0.508
K71.0 Toxic liver disease with cholestasis
0.000 0.491 0.508
L53.9 Erythematous condition, unspecified
0.000 0.493 0.507
H54.6 Unqualified visual loss, one eye
0.000 0.493 0.507
H31.3 Choroidal haemorrhage and rupture
0.000 0.493 0.507
L13.0 Dermatitis herpetiformis
0.000 0.494 0.506
L51.9 Erythema multiforme, unspecified
0.000 0.495 0.505
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.495 0.505
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.495 0.505
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.495 0.504
J92 Pleural plaque
0.000 0.496 0.504
J43.2 Centrilobular emphysema
0.000 0.499 0.501
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.499 0.501
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.499 0.501
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.499 0.501
H68.1 Obstruction of Eustachian tube
0.000 0.499 0.501
H68.0 Eustachian salpingitis
0.000 0.499 0.501
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.499 0.501
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.499 0.501
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.499 0.501

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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