TreeWAS – Variant ID: rs2075798

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.862	0.138	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.859	0.141	0.000
K57 Diverticular disease of intestine	0.856	0.144	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.696	0.304	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.370	0.630
E10-E14 Diabetes mellitus	0.000	0.375	0.625
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.613	0.386	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.613	0.386	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.613	0.386	0.000
E10.3 With ophthalmic complications	0.000	0.387	0.613
E14 Unspecified diabetes mellitus	0.000	0.389	0.611
E10.9 Without complications	0.000	0.403	0.597
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.580	0.420	0.000
E14.3 With ophthalmic complications	0.000	0.425	0.574
E03.9 Hypothyroidism, unspecified	0.000	0.438	0.562
E14.9 Without complications	0.000	0.439	0.561
E03 Other hypothyroidism	0.000	0.446	0.554
K57.1 Diverticular disease of small intestine without perforation or abscess	0.548	0.452	0.000
E00-E07 Disorders of thyroid gland	0.000	0.454	0.546
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.459	0.541
E10.5 With peripheral circulatory complications	0.000	0.470	0.530
E10.1 With ketoacidosis	0.000	0.474	0.526
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.495	0.505
E11 Non-insulin-dependent diabetes mellitus	0.000	0.495	0.505
K90 Intestinal malabsorption	0.000	0.503	0.497
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.534	0.466
E11.5 With peripheral circulatory complications	0.000	0.547	0.453
E10.8 With unspecified complications	0.000	0.548	0.452
E10.7 With multiple complications	0.000	0.548	0.452
E10.6 With other specified complications	0.000	0.548	0.452
E10.0 With coma	0.000	0.548	0.452
E10.2 With renal complications	0.000	0.548	0.452
E12 Malnutrition-related diabetes mellitus	0.000	0.552	0.448
E13 Other specified diabetes mellitus	0.000	0.552	0.448
E05.9 Thyrotoxicosis, unspecified	0.000	0.556	0.444
E03.8 Other specified hypothyroidism	0.000	0.557	0.443
E14.8 With unspecified complications	0.000	0.562	0.438
E14.7 With multiple complications	0.000	0.562	0.438
E14.6 With other specified complications	0.000	0.562	0.438
E14.5 With peripheral circulatory complications	0.000	0.562	0.438
E14.4 With neurological complications	0.000	0.562	0.438
E14.2 Withrenal complications	0.000	0.562	0.438
E14.1 With ketoacidosis	0.000	0.562	0.438
E14.0 With coma	0.000	0.562	0.438
E11.2 With renal complications	0.000	0.569	0.431
E50-E64 Other nutritional deficiencies	0.000	0.579	0.421
E10.4 With neurological complications	0.000	0.583	0.417
E06 Thyroiditis	0.000	0.593	0.407
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.602	0.398
E03.5 Myxoedema coma	0.000	0.603	0.397
E03.4 Atrophy of thyroid (acquired)	0.000	0.603	0.397
E03.3 Postinfectious hypothyroidism	0.000	0.603	0.397
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.603	0.397
E03.1 Congenital hypothyroidism without goitre	0.000	0.603	0.397
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.603	0.397
E65-E68 Obesity and other hyperalimentation	0.000	0.608	0.392
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.609	0.391
E00 Congenital iodine-deficiency syndrome	0.000	0.609	0.391
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.609	0.391
E11.1 With ketoacidosis	0.000	0.622	0.378
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.622	0.378
E11.6 With other specified complications	0.000	0.628	0.372
E05.5 Thyroid crisis or storm	0.000	0.637	0.362
E05.4 Thyrotoxicosis factitia	0.000	0.637	0.362
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.637	0.362
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.637	0.362
E11.7 With multiple complications	0.000	0.638	0.362
E40-E46 Malnutrition	0.000	0.640	0.360
E11.8 With unspecified complications	0.000	0.643	0.357
K90.8 Other intestinal malabsorption	0.000	0.644	0.356
K90.3 Pancreatic steatorrhoea	0.000	0.644	0.356
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.644	0.356
K90.1 Tropical sprue	0.000	0.644	0.356
E11.9 Without complications	0.000	0.659	0.341
E53 Deficiency of other B group vitamins	0.000	0.669	0.331
E11.4 With neurological complications	0.000	0.675	0.325
E05.8 Other thyrotoxicosis	0.000	0.676	0.324
K90.9 Intestinal malabsorption, unspecified	0.000	0.678	0.322
E12.9 Without complications	0.000	0.678	0.321
E12.8 With unspecified complications	0.000	0.678	0.321
E12.7 With multiple complications	0.000	0.678	0.321
E12.6 With other specified complications	0.000	0.678	0.321
E12.5 With peripheral circulatory complications	0.000	0.678	0.321
E12.4 With neurological complications	0.000	0.678	0.321
E12.3 With ophthalmic complications	0.000	0.678	0.321
E12.2 With renal complications	0.000	0.678	0.321
E12.1 With ketoacidosis	0.000	0.678	0.321
E12.0 With coma	0.000	0.678	0.321
E13.8 With unspecified complications	0.000	0.678	0.321
E13.7 With multiple complications	0.000	0.678	0.321
E13.6 With other specified complications	0.000	0.678	0.321
E13.5 With peripheral circulatory complications	0.000	0.678	0.321
E13.4 With neurological complications	0.000	0.678	0.321
E13.3 With ophthalmic complications	0.000	0.678	0.321
E13.2 With renal complications	0.000	0.678	0.321
E13.1 With ketoacidosis	0.000	0.678	0.321
E13.0 With coma	0.000	0.678	0.321
E13.9 Without complications	0.000	0.678	0.321
E61 Deficiency of other nutrient elements	0.000	0.683	0.317
E07 Other disorders of thyroid	0.000	0.685	0.314
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.689	0.311
E06.3 Autoimmune thyroiditis	0.000	0.693	0.307
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.698	0.302
E63 Other nutritional deficiencies	0.000	0.698	0.302
E56 Other vitamin deficiencies	0.000	0.698	0.302
E51 Thiamine deficiency	0.000	0.698	0.302
E50 Vitamin A deficiency	0.000	0.698	0.302
E60 Dietary zinc deficiency	0.000	0.698	0.302
E59 Dietary selenium deficiency	0.000	0.698	0.302
E58 Dietary calcium deficiency	0.000	0.698	0.302
E54 Ascorbic acid deficiency	0.000	0.698	0.302
E52 Niacin deficiency [pellagra]	0.000	0.698	0.302
E11.0 With coma	0.000	0.707	0.293
E55 Vitamin D deficiency	0.000	0.707	0.293
E06.9 Thyroiditis, unspecified	0.000	0.708	0.292
E06.5 Other chronic thyroiditis	0.000	0.708	0.292
E06.4 Drug-induced thyroiditis	0.000	0.708	0.292
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.708	0.292
E06.1 Subacute thyroiditis	0.000	0.708	0.292
E06.0 Acute thyroiditis	0.000	0.708	0.292
E66 Obesity	0.000	0.713	0.287
E53.8 Deficiency of other specified B group vitamins	0.000	0.717	0.283
E67 Other hyperalimentation	0.000	0.719	0.281
E68 Sequelae of hyperalimentation	0.000	0.719	0.281
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.719	0.281
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.719	0.281
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.719	0.281
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.719	0.281
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.719	0.281
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.719	0.281
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.719	0.281
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.719	0.281
E65 Localised adiposity	0.000	0.721	0.279
E15 Nondiabetic hypoglycaemic coma	0.000	0.729	0.271
E16 Other disorders of pancreatic internal secretion	0.000	0.738	0.262
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.741	0.258
E45 Retarded development following protein-energy malnutrition	0.000	0.741	0.258
E43 Unspecified severe protein-energy malnutrition	0.000	0.741	0.258
E42 Marasmic kwashiorkor	0.000	0.741	0.258
E41 Nutritional marasmus	0.000	0.741	0.258
E40 Kwashiorkor	0.000	0.741	0.258
E11.3 With ophthalmic complications	0.000	0.745	0.255
E66.9 Obesity, unspecified	0.000	0.746	0.254
M20 Acquired deformities of fingers and toes	0.249	0.751	0.000
M20.1 Hallux valgus (acquired)	0.248	0.752	0.000
M20.5 Other deformities of toe(s) (acquired)	0.247	0.753	0.000
E61.1 Iron deficiency	0.000	0.758	0.242
E53.1 Pyridoxine deficiency	0.000	0.763	0.237
E53.0 Riboflavin deficiency	0.000	0.763	0.237
E46 Unspecified protein-energy malnutrition	0.000	0.769	0.231
E61.9 Deficiency of nutrient element, unspecified	0.000	0.772	0.227
E61.8 Deficiency of other specified nutrient elements	0.000	0.772	0.227
E61.7 Deficiency of multiple nutrient elements	0.000	0.772	0.227
E61.6 Vanadium deficiency	0.000	0.772	0.227
E61.5 Molybdenum deficiency	0.000	0.772	0.227
E61.4 Chromium deficiency	0.000	0.772	0.227
E61.3 Manganese deficiency	0.000	0.772	0.227
E61.2 Magnesium deficiency	0.000	0.772	0.227
E61.0 Copper deficiency	0.000	0.772	0.227
E07.8 Other specified disorders of thyroid	0.000	0.774	0.225
E07.1 Dyshormogenetic goitre	0.000	0.774	0.225
E07.0 Hypersecretion of calcitonin	0.000	0.774	0.225
E50.9 Vitamin A deficiency, unspecified	0.000	0.783	0.217
E50.8 Other manifestations of vitamin A deficiency	0.000	0.783	0.217
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.783	0.217
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.783	0.217
E50.5 Vitamin A deficiency with night blindness	0.000	0.783	0.217
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.783	0.217
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.783	0.217
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.783	0.217
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.783	0.217
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.783	0.217
E51.9 Thiamine deficiency, unspecified	0.000	0.783	0.217
E51.8 Other manifestations of thiamine deficiency	0.000	0.783	0.217
E51.2 Wernicke's encephalopathy	0.000	0.783	0.217
E51.1 Beriberi	0.000	0.783	0.217
E56.9 Vitamin deficiency, unspecified	0.000	0.783	0.217
E56.8 Deficiency of other vitamins	0.000	0.783	0.217
E56.1 Deficiency of vitamin K	0.000	0.783	0.217
E56.0 Deficiency of vitamin E	0.000	0.783	0.217
E63.9 Nutritional deficiency, unspecified	0.000	0.783	0.217
E63.8 Other specified nutritional deficiencies	0.000	0.783	0.217
E63.1 Imbalance of constituents of food intake	0.000	0.783	0.217
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.783	0.217
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.783	0.217
E64.8 Sequelae of other nutritional deficiencies	0.000	0.783	0.217
E64.3 Sequelae of rickets	0.000	0.783	0.217
E64.2 Sequelae of vitamin C deficiency	0.000	0.783	0.217
E64.1 Sequelae of vitamin A deficiency	0.000	0.783	0.217
E64.0 Sequelae of protein-energy malnutrition	0.000	0.783	0.217
M20.4 Other hammer toe(s) (acquired)	0.215	0.785	0.000
E55.0 Rickets, active	0.000	0.790	0.210
M20.2 Hallux rigidus	0.206	0.794	0.000
E66.1 Drug-induced obesity	0.000	0.794	0.206
E53.9 Vitamin B deficiency, unspecified	0.000	0.795	0.205
E67.8 Other specified hyperalimentation	0.000	0.798	0.202
E67.3 Hypervitaminosis D	0.000	0.798	0.202
E67.2 Megavitamin-B6 syndrome	0.000	0.798	0.202
E67.1 Hypercarotenaemia	0.000	0.798	0.202
E67.0 Hypervitaminosis A	0.000	0.798	0.202
E66.0 Obesity due to excess calories	0.000	0.799	0.201
E55.9 Vitamin D deficiency, unspecified	0.000	0.799	0.201
M20.3 Other deformity of hallux (acquired)	0.199	0.801	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.801	0.199
M20.0 Deformity of finger(s)	0.191	0.809	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.812	0.188
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.812	0.188
E16.4 Abnormal secretion of gastrin	0.000	0.812	0.188
E16.3 Increased secretion of glucagon	0.000	0.812	0.188
E16.1 Other hypoglycaemia	0.000	0.812	0.188
E16.2 Hypoglycaemia, unspecified	0.000	0.812	0.188
E44.1 Mild protein-energy malnutrition	0.000	0.814	0.185
E44.0 Moderate protein-energy malnutrition	0.000	0.814	0.185
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.821	0.178
M20.6 Acquired deformity of toe(s), unspecified	0.171	0.829	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.851	0.148
E04 Other non-toxic goitre	0.000	0.861	0.139
E66.8 Other obesity	0.000	0.875	0.125
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.120	0.880	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.882	0.118
M20-M25 Other joint disorders	0.105	0.895	0.000
E04.8 Other specified non-toxic goitre	0.000	0.900	0.100
E04.0 Non-toxic diffuse goitre	0.000	0.900	0.100
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.099	0.901	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.098	0.902	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.093	0.907	0.000
M31 Other necrotising vasculopathies	0.090	0.910	0.000
M95.0 Acquired deformity of nose	0.089	0.911	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.088	0.912	0.000
M65-M68 Disorders of synovium and tendon	0.088	0.912	0.000
M80-M85 Disorders of bone density and structure	0.087	0.913	0.000
K90-K93 Other diseases of the digestive system	0.001	0.914	0.086
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.915	0.085
E32 Diseases of thymus	0.000	0.915	0.085
E31 Polyglandular dysfunction	0.000	0.915	0.085
E30 Disorders of puberty, not elsewhere classified	0.000	0.915	0.085
E25 Adrenogenital disorders	0.000	0.915	0.085
E20 Hypoparathyroidism	0.000	0.915	0.085
E26 Hyperaldosteronism	0.000	0.915	0.084
E29 Testicular dysfunction	0.000	0.916	0.084
M96.0 Pseudarthrosis after fusion or arthrodesis	0.084	0.916	0.000
M65 Synovitis and tenosynovitis	0.083	0.917	0.000
M31.6 Other giant cell arteritis	0.083	0.917	0.000
M60-M63 Disorders of muscles	0.079	0.921	0.000
M91-M94 Chondropathies	0.079	0.921	0.000
M33 Dermatopolymyositis	0.078	0.922	0.000
M40-M43 Deforming dorsopathies	0.078	0.922	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.923	0.077
M30 Polyarteritis nodosa and related conditions	0.077	0.923	0.000
E34 Other endocrine disorders	0.000	0.924	0.076
M85 Other disorders of bone density and structure	0.075	0.925	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.075	0.925	0.000
M32 Systemic lupus erythematosus	0.075	0.925	0.000
M86-M90 Other osteopathies	0.075	0.925	0.000
E24 Cushing's syndrome	0.000	0.925	0.075
M00-M03 Infectious arthropathies	0.075	0.925	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.926	0.073
E23 Hypofunction and other disorders of pituitary gland	0.000	0.927	0.073
M15-M19 Arthrosis	0.073	0.927	0.000
M65.3 Trigger finger	0.072	0.928	0.000
M95.2 Other acquired deformity of head	0.072	0.928	0.000
M65.1 Other infective (teno)synovitis	0.072	0.928	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.928	0.071
E28 Ovarian dysfunction	0.000	0.929	0.070
M82 Osteoporosis in diseases classified elsewhere	0.070	0.929	0.000
M99 Biomechanical lesions, not elsewhere classified	0.070	0.930	0.000
E27 Other disorders of adrenal gland	0.000	0.930	0.070
M80 Osteoporosis with pathological fracture	0.069	0.931	0.000
M45-M49 Spondylopathies	0.068	0.932	0.000
M34 Systemic sclerosis	0.068	0.932	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.067	0.933	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.067	0.933	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.067	0.933	0.000
M95.5 Acquired deformity of pelvis	0.067	0.933	0.000
M95.4 Acquired deformity of chest and rib	0.067	0.933	0.000
M95.3 Acquired deformity of neck	0.067	0.933	0.000
M95.1 Cauliflower ear	0.067	0.933	0.000
M16 Coxarthrosis [arthrosis of hip]	0.066	0.934	0.000
M85.8 Other specified disorders of bone density and structure	0.065	0.935	0.000
M31.9 Necrotising vasculopathy, unspecified	0.065	0.935	0.000
M31.8 Other specified necrotising vasculopathies	0.065	0.935	0.000
M31.7 Microscopic polyangiitis	0.065	0.935	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.065	0.935	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.065	0.935	0.000
M31.2 Lethal midline granuloma	0.065	0.935	0.000
M31.1 Thrombotic microangiopathy	0.065	0.935	0.000
M31.0 Hypersensitivity angiitis	0.065	0.935	0.000
M65.34 Trigger finger-Hand	0.065	0.935	0.000
E22 Hyperfunction of pituitary gland	0.000	0.935	0.064
M35 Other systemic involvement of connective tissue	0.065	0.935	0.000
M21 Other acquired deformities of limbs	0.064	0.936	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.064	0.936	0.000
M65.8 Other synovitis and tenosynovitis	0.064	0.936	0.000
M40 Kyphosis and lordosis	0.064	0.936	0.000
M62 Other disorders of muscle	0.064	0.936	0.000
M24 Other specific joint derangements	0.063	0.936	0.000
M16.1 Other primary coxarthrosis	0.064	0.936	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.063	0.937	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.063	0.937	0.000
M96.5 Postradiation scoliosis	0.063	0.937	0.000
M96.4 Postsurgical lordosis	0.063	0.937	0.000
M96.3 Postlaminectomy kyphosis	0.063	0.937	0.000
M96.2 Postradiation kyphosis	0.063	0.937	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.063	0.937	0.000
M90 Osteopathies in diseases classified elsewhere	0.063	0.937	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.063	0.937	0.000
M92 Other juvenile osteochondrosis	0.063	0.937	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.062	0.938	0.000
M83 Adult osteomalacia	0.062	0.938	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.001	0.938	0.062
M41 Scoliosis	0.061	0.938	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.939	0.061
E20.8 Other hypoparathyroidism	0.000	0.939	0.061
E20.1 Pseudohypoparathyroidism	0.000	0.939	0.061
E20.0 Idiopathic hypoparathyroidism	0.000	0.939	0.061
E25.9 Adrenogenital disorder, unspecified	0.000	0.939	0.061
E25.8 Other adrenogenital disorders	0.000	0.939	0.061
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.939	0.061
E30.9 Disorder of puberty, unspecified	0.000	0.939	0.061
E30.8 Other disorders of puberty	0.000	0.939	0.061
E30.1 Precocious puberty	0.000	0.939	0.061
E30.0 Delayed puberty	0.000	0.939	0.061
E31.9 Polyglandular dysfunction, unspecified	0.000	0.939	0.061
E31.8 Other polyglandular dysfunction	0.000	0.939	0.061
E31.1 Polyglandular hyperfunction	0.000	0.939	0.061
E31.0 Autoimmune polyglandular failure	0.000	0.939	0.061
E32.9 Disease of thymus, unspecified	0.000	0.939	0.061
E32.8 Other diseases of thymus	0.000	0.939	0.061
E32.1 Abscess of thymus	0.000	0.939	0.061
E32.0 Persistent hyperplasia of thymus	0.000	0.939	0.061
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.939	0.061
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.939	0.061
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.939	0.061
M94 Other disorders of cartilage	0.061	0.939	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.939	0.061
E26.8 Other hyperaldosteronism	0.000	0.939	0.061
E26.1 Secondary hyperaldosteronism	0.000	0.939	0.061
E26.0 Primary hyperaldosteronism	0.000	0.939	0.061
M84 Disorders of continuity of bone	0.061	0.939	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.939	0.060
E29.8 Other testicular dysfunction	0.000	0.939	0.060
E29.0 Testicular hyperfunction	0.000	0.939	0.060
M18 Arthrosis of first carpometacarpal joint	0.061	0.939	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.060	0.940	0.000
E29.1 Testicular hypofunction	0.000	0.940	0.060
M65.2 Calcific tendinitis	0.060	0.940	0.000
M65.0 Abscess of tendon sheath	0.060	0.940	0.000
M66 Spontaneous rupture of synovium and tendon	0.060	0.940	0.000
M33.2 Polymyositis	0.059	0.941	0.000
M82.1 Osteoporosis in endocrine disorders	0.059	0.941	0.000
M60 Myositis	0.058	0.942	0.000
E23.2 Diabetes insipidus	0.000	0.942	0.057
M48 Other spondylopathies	0.057	0.942	0.000
M00 Pyogenic arthritis	0.057	0.942	0.000
M16.5 Other posttraumatic coxarthrosis	0.057	0.943	0.000
M85.6 Other cyst of bone	0.057	0.943	0.000
M31.3 Wegener's granulomatosis	0.057	0.943	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.057	0.943	0.000
M61 Calcification and ossification of muscle	0.057	0.943	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.057	0.943	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.057	0.943	0.000
M87 Osteonecrosis	0.056	0.944	0.000
M05-M14 Inflammatory polyarthropathies	0.056	0.944	0.000
M33.9 Dermatopolymyositis, unspecified	0.056	0.944	0.000
M33.1 Other dermatomyositis	0.056	0.944	0.000
M33.0 Juvenile dermatomyositis	0.056	0.944	0.000
M42 Spinal osteochondrosis	0.056	0.944	0.000
M85.0 Fibrous dysplasia (monostotic)	0.056	0.944	0.000
M24.2 Disorder of ligament	0.055	0.944	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.945	0.055
E21.4 Other specified disorders of parathyroid gland	0.000	0.945	0.055
E21.2 Other hyperparathyroidism	0.000	0.945	0.055
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.945	0.055
M30.8 Other conditions related to polyarteritis nodosa	0.055	0.945	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.055	0.945	0.000
M30.2 Juvenile polyarteritis	0.055	0.945	0.000
M30.0 Polyarteritis nodosa	0.055	0.945	0.000
E34.8 Other specified endocrine disorders	0.000	0.945	0.055
E34.5 Androgen resistance syndrome	0.000	0.945	0.055
E34.4 Constitutional tall stature	0.000	0.945	0.055
E34.3 Short stature, not elsewhere classified	0.000	0.945	0.055
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.945	0.055
E34.1 Other hypersecretion of intestinal hormones	0.000	0.945	0.055
E34.0 Carcinoid syndrome	0.000	0.945	0.055
M90.7 Fracture of bone in neoplastic disease	0.055	0.945	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.055	0.945	0.000
M85.9 Disorder of bone density and structure, unspecified	0.054	0.946	0.000
M85.5 Aneurysmal bone cyst	0.054	0.946	0.000
M85.4 Solitary bone cyst	0.054	0.946	0.000
M85.3 Osteitis condensans	0.054	0.946	0.000
M85.2 Hyperostosis of skull	0.054	0.946	0.000
M85.1 Skeletal fluorosis	0.054	0.946	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.946	0.054
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.054	0.946	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.054	0.946	0.000
M32.8 Other forms of systemic lupus erythematosus	0.054	0.946	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.054	0.946	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.054	0.946	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.054	0.946	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.054	0.946	0.000
M36.3 Arthropathy in other blood disorders	0.054	0.946	0.000
M36.2 Haemophilic arthropathy	0.054	0.946	0.000
M36.1 Arthropathy in neoplastic disease	0.054	0.946	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.054	0.946	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.054	0.946	0.000
E24.8 Other Cushing's syndrome	0.000	0.946	0.054
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.946	0.054
E24.3 Ectopic ACTH syndrome	0.000	0.946	0.054
E24.2 Drug-induced Cushing's syndrome	0.000	0.946	0.054
E24.1 Nelson's syndrome	0.000	0.946	0.054
E24.0 Pituitary-dependent Cushing's disease	0.000	0.946	0.054
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.054	0.946	0.000
M02 Reactive arthropathies	0.054	0.946	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.054	0.946	0.000
M93 Other osteochondropathies	0.053	0.946	0.000
M40.2 Other and unspecified kyphosis	0.053	0.947	0.000
M67 Other disorders of synovium and tendon	0.053	0.947	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.053	0.947	0.000
M88 Paget's disease of bone [osteitis deformans]	0.053	0.947	0.000
M62.8 Other specified disorders of muscle	0.053	0.947	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.947	0.052
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.947	0.052
E23.1 Drug-induced hypopituitarism	0.000	0.947	0.052
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.052	0.947	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.052	0.948	0.000
M15 Polyarthrosis	0.052	0.948	0.000
M65.39 Trigger finger-Site unspec	0.052	0.948	0.000
M65.38 Trigger finger-Other	0.052	0.948	0.000
M65.37 Trigger finger-Ankle/foot	0.052	0.948	0.000
M65.36 Trigger finger-Lower leg	0.052	0.948	0.000
M65.35 Trigger finger-Pelvic/thigh	0.052	0.948	0.000
M65.33 Trigger finger-Forearm	0.052	0.948	0.000
M65.32 Trigger finger-Upper arm	0.052	0.948	0.000
M65.31 Trigger finger-Shldr region	0.052	0.948	0.000
M65.30 Trigger finger-Mult sites	0.052	0.948	0.000
M86 Osteomyelitis	0.052	0.948	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.948	0.052
M96.8 Other postprocedural musculoskeletal disorders	0.052	0.948	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.052	0.948	0.000
M65.18 Other infective (teno)synovitis (Other)	0.052	0.948	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.052	0.948	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.052	0.948	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.052	0.948	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.052	0.948	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.052	0.948	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.052	0.948	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.052	0.948	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.052	0.948	0.000
M48.0 Spinal stenosis	0.051	0.949	0.000
M70-M79 Other soft tissue disorders	0.051	0.949	0.000
M21.4 Flat foot [pes planus] (acquired)	0.051	0.949	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.949	0.051
E28.8 Other ovarian dysfunction	0.000	0.949	0.051
E28.1 Androgen excess	0.000	0.949	0.051
E28.0 Oestrogen excess	0.000	0.949	0.051
M82.8 Osteoporosis in other diseases classified elsewhere	0.051	0.949	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.051	0.949	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.051	0.949	0.000
M99.9 Biomechanical lesion, unspecified	0.051	0.949	0.000
M99.8 Other biomechanical lesions	0.051	0.949	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.051	0.949	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.051	0.949	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.051	0.949	0.000
M99.4 Connective tissue stenosis of neural canal	0.051	0.949	0.000
M99.3 Osseous stenosis of neural canal	0.051	0.949	0.000
M99.2 Subluxation stenosis of neural canal	0.051	0.949	0.000
M99.1 Subluxation complex (vertebral)	0.051	0.949	0.000
M99.0 Segmental and somatic dysfunction	0.051	0.949	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.051	0.949	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.051	0.949	0.000
M49 Spondylopathies in diseases classified elsewhere	0.050	0.949	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.949	0.050
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.949	0.050
E27.2 Addisonian crisis	0.000	0.949	0.050
E27.0 Other adrenocortical overactivity	0.000	0.949	0.050
M48.02 Spinal stenosis (Cervical region)	0.051	0.949	0.000
M46 Other inflammatory spondylopathies	0.050	0.950	0.000
M34.8 Other forms of systemic sclerosis	0.050	0.950	0.000
M80.8 Other osteoporosis with pathological fracture	0.050	0.950	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.050	0.950	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.050	0.950	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.050	0.950	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.050	0.950	0.000
M41.9 Scoliosis, unspecified	0.050	0.950	0.000
E28.3 Primary ovarian failure	0.000	0.950	0.049
M35.0 Sicca syndrome [Sjogren]	0.049	0.951	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.049	0.951	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.049	0.951	0.000
M24.5 Contracture of joint	0.049	0.951	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.049	0.951	0.000
M34.0 Progressive systemic sclerosis	0.049	0.951	0.000
E21.0 Primary hyperparathyroidism	0.000	0.951	0.049
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.048	0.951	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.048	0.951	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.048	0.951	0.000
M16.7 Other secondary coxarthrosis	0.048	0.951	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.048	0.952	0.000
M43 Other deforming dorsopathies	0.048	0.952	0.000
M24.24 Disorder of ligament (Hand)	0.048	0.952	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations