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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs209152
log Bayes Factor = 52.9416
Chromosome 6   position 28,846,462  (GRCh37) Explore rs209152 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.005 0.995
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.010 0.990
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.014 0.986
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.015 0.985
E16 Other disorders of pancreatic internal secretion
0.000 0.016 0.984
E16.2 Hypoglycaemia, unspecified
0.000 0.016 0.984
E00-E07 Disorders of thyroid gland
0.000 0.018 0.982
E10.2 With renal complications
0.000 0.032 0.968
E10.1 With ketoacidosis
0.000 0.080 0.920
E10.4 With neurological complications
0.000 0.082 0.918
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.096 0.904
E05.8 Other thyrotoxicosis
0.000 0.182 0.818
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.204 0.796
E16.1 Other hypoglycaemia
0.000 0.218 0.782
E14 Unspecified diabetes mellitus
0.000 0.226 0.774
E13 Other specified diabetes mellitus
0.000 0.244 0.756
E10.0 With coma
0.000 0.263 0.737
E10.7 With multiple complications
0.000 0.274 0.725
E05.5 Thyroid crisis or storm
0.000 0.290 0.710
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.710
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.710
E12 Malnutrition-related diabetes mellitus
0.000 0.290 0.710
E15 Nondiabetic hypoglycaemic coma
0.000 0.294 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.294 0.706
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.294 0.706
E16.4 Abnormal secretion of gastrin
0.000 0.294 0.706
E16.3 Increased secretion of glucagon
0.000 0.294 0.706
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.296 0.704
E00 Congenital iodine-deficiency syndrome
0.000 0.296 0.704
E14.3 With ophthalmic complications
0.000 0.304 0.696
E40-E46 Malnutrition
0.000 0.329 0.671
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.657 0.343 0.000
E10.6 With other specified complications
0.000 0.346 0.654
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.364 0.636
E10.5 With peripheral circulatory complications
0.000 0.366 0.634
E07 Other disorders of thyroid
0.000 0.381 0.619
E14.6 With other specified complications
0.000 0.386 0.614
E14.1 With ketoacidosis
0.000 0.388 0.612
E13.9 Without complications
0.000 0.418 0.582
E06 Thyroiditis
0.000 0.433 0.567
E14.4 With neurological complications
0.000 0.436 0.564
E10.8 With unspecified complications
0.000 0.444 0.556
E14.7 With multiple complications
0.000 0.445 0.555
E13.3 With ophthalmic complications
0.000 0.450 0.550
E14.8 With unspecified complications
0.000 0.452 0.548
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.453 0.547
E13.8 With unspecified complications
0.000 0.458 0.542
E13.7 With multiple complications
0.000 0.458 0.542
E13.6 With other specified complications
0.000 0.458 0.542
E13.5 With peripheral circulatory complications
0.000 0.458 0.542
E13.4 With neurological complications
0.000 0.458 0.542
E13.2 With renal complications
0.000 0.458 0.542
E13.1 With ketoacidosis
0.000 0.458 0.542
E13.0 With coma
0.000 0.458 0.542
E14.2 Withrenal complications
0.000 0.465 0.535
E14.5 With peripheral circulatory complications
0.000 0.469 0.531
E14.0 With coma
0.000 0.478 0.522
E12.9 Without complications
0.000 0.491 0.509
E12.8 With unspecified complications
0.000 0.491 0.509
E12.7 With multiple complications
0.000 0.491 0.509
E12.6 With other specified complications
0.000 0.491 0.509
E12.5 With peripheral circulatory complications
0.000 0.491 0.509
E12.4 With neurological complications
0.000 0.491 0.509
E12.3 With ophthalmic complications
0.000 0.491 0.509
E12.2 With renal complications
0.000 0.491 0.509
E12.1 With ketoacidosis
0.000 0.491 0.509
E12.0 With coma
0.000 0.491 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.495 0.505
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.495 0.505
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.495 0.505
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.495 0.505
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.495 0.505
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.495 0.505
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.495 0.505
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.495 0.505
E07.8 Other specified disorders of thyroid
0.000 0.511 0.489
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.519 0.481
E45 Retarded development following protein-energy malnutrition
0.000 0.519 0.481
E43 Unspecified severe protein-energy malnutrition
0.000 0.519 0.481
E42 Marasmic kwashiorkor
0.000 0.519 0.481
E41 Nutritional marasmus
0.000 0.519 0.481
E40 Kwashiorkor
0.000 0.519 0.481
E06.9 Thyroiditis, unspecified
0.000 0.543 0.457
E46 Unspecified protein-energy malnutrition
0.000 0.555 0.445
E07.1 Dyshormogenetic goitre
0.000 0.556 0.444
E07.0 Hypersecretion of calcitonin
0.000 0.556 0.444
E06.1 Subacute thyroiditis
0.000 0.571 0.429
E06.4 Drug-induced thyroiditis
0.000 0.593 0.407
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.593 0.407
E06.0 Acute thyroiditis
0.000 0.593 0.407
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.608 0.391
E50-E64 Other nutritional deficiencies
0.000 0.620 0.380
E06.5 Other chronic thyroiditis
0.000 0.623 0.376
K90 Intestinal malabsorption
0.000 0.628 0.372
E11 Non-insulin-dependent diabetes mellitus
0.000 0.655 0.345
E44.1 Mild protein-energy malnutrition
0.000 0.655 0.345
E44.0 Moderate protein-energy malnutrition
0.000 0.655 0.345
E03 Other hypothyroidism
0.000 0.660 0.340
E70-E90 Metabolic disorders
0.001 0.680 0.319
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.685 0.315
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.687 0.313
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.689 0.311
E65-E68 Obesity and other hyperalimentation
0.000 0.691 0.309
E11.6 With other specified complications
0.000 0.694 0.306
E78.2 Mixed hyperlipidaemia
0.000 0.694 0.306
C15 Malignant neoplasm of oesophagus
0.000 0.699 0.301
E11.1 With ketoacidosis
0.000 0.700 0.300
C15-C26 Malignant neoplasms of digestive organs
0.000 0.703 0.297
E78.5 Hyperlipidaemia, unspecified
0.000 0.708 0.292
C20 Malignant neoplasm of rectum
0.000 0.709 0.291
C15.9 Oesophagus, unspecified
0.000 0.721 0.279
E54 Ascorbic acid deficiency
0.000 0.721 0.278
C15.5 Lower third of oesophagus
0.000 0.722 0.278
E78.1 Pure hyperglyceridaemia
0.000 0.725 0.275
C15.4 Middle third of oesophagus
0.000 0.726 0.274
E51 Thiamine deficiency
0.000 0.727 0.273
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.727 0.273
E63 Other nutritional deficiencies
0.000 0.727 0.273
E50 Vitamin A deficiency
0.000 0.727 0.273
E60 Dietary zinc deficiency
0.000 0.727 0.273
E59 Dietary selenium deficiency
0.000 0.727 0.273
E52 Niacin deficiency [pellagra]
0.000 0.727 0.273
E11.0 With coma
0.000 0.728 0.272
E07.9 Disorder of thyroid, unspecified
0.000 0.730 0.269
E11.2 With renal complications
0.000 0.732 0.268
K90.3 Pancreatic steatorrhoea
0.000 0.733 0.267
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.733 0.267
K90.1 Tropical sprue
0.000 0.733 0.267
E55 Vitamin D deficiency
0.000 0.735 0.265
K90.8 Other intestinal malabsorption
0.000 0.741 0.259
E56 Other vitamin deficiencies
0.000 0.741 0.259
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.744 0.256
E78.6 Lipoprotein deficiency
0.000 0.744 0.256
C25 Malignant neoplasm of pancreas
0.000 0.746 0.254
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.747 0.252
E83 Disorders of mineral metabolism
0.163 0.748 0.089
E74 Other disorders of carbohydrate metabolism
0.001 0.749 0.251
E88 Other metabolic disorders
0.000 0.751 0.249
E11.7 With multiple complications
0.000 0.752 0.248
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.754 0.246
E03.5 Myxoedema coma
0.000 0.756 0.244
E03.4 Atrophy of thyroid (acquired)
0.000 0.756 0.244
E03.3 Postinfectious hypothyroidism
0.000 0.756 0.244
E58 Dietary calcium deficiency
0.000 0.760 0.239
E78.3 Hyperchylomicronaemia
0.000 0.761 0.239
E85 Amyloidosis
0.001 0.763 0.236
E03.1 Congenital hypothyroidism without goitre
0.000 0.763 0.237
E73 Lactose intolerance
0.001 0.764 0.235
C15.0 Cervical part of oesophagus
0.000 0.766 0.234
C15.3 Upper third of oesophagus
0.000 0.769 0.231
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.770 0.230
E77 Disorders of glycoprotein metabolism
0.001 0.770 0.229
E76 Disorders of glycosaminoglycan metabolism
0.001 0.770 0.229
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.770 0.229
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.770 0.229
E84 Cystic fibrosis
0.001 0.773 0.227
E67 Other hyperalimentation
0.000 0.778 0.222
E68 Sequelae of hyperalimentation
0.000 0.778 0.222
C15.1 Thoracic part of oesophagus
0.000 0.780 0.220
C17 Malignant neoplasm of small intestine
0.000 0.782 0.218
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.782 0.218
C15.8 Overlapping lesion of oesophagus
0.000 0.784 0.216
C15.2 Abdominal part of oesophagus
0.000 0.784 0.216
E79 Disorders of purine and pyrimidine metabolism
0.001 0.784 0.215
E11.8 With unspecified complications
0.000 0.786 0.213
C25.2 Tail of pancreas
0.000 0.787 0.213
E70 Disorders of aromatic amino-acid metabolism
0.001 0.787 0.212
C25.3 Pancreatic duct
0.000 0.787 0.213
E88.9 Metabolic disorder, unspecified
0.000 0.789 0.211
E72 Other disorders of amino-acid metabolism
0.001 0.790 0.209
C25.1 Body of pancreas
0.000 0.790 0.210
E61 Deficiency of other nutrient elements
0.000 0.792 0.208
C17.0 Duodenum
0.000 0.794 0.206
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.795 0.205
E78.4 Other hyperlipidaemia
0.000 0.797 0.203
E75.5 Other lipid storage disorders
0.000 0.798 0.202
E53 Deficiency of other B group vitamins
0.000 0.799 0.200
E85.4 Organ-limited amyloidosis
0.000 0.800 0.200
E03.8 Other specified hypothyroidism
0.000 0.800 0.200
C25.8 Overlapping lesion of pancreas
0.000 0.801 0.199
C25.4 Endocrine pancreas
0.000 0.802 0.198
E14.9 Without complications
0.000 0.803 0.197
E51.2 Wernicke's encephalopathy
0.000 0.804 0.196
E51.9 Thiamine deficiency, unspecified
0.000 0.804 0.196
E51.8 Other manifestations of thiamine deficiency
0.000 0.804 0.196
E51.1 Beriberi
0.000 0.804 0.196
E50.9 Vitamin A deficiency, unspecified
0.000 0.804 0.196
E50.8 Other manifestations of vitamin A deficiency
0.000 0.804 0.196
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.804 0.196
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.804 0.196
E50.5 Vitamin A deficiency with night blindness
0.000 0.804 0.196
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.804 0.196
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.804 0.196
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.804 0.196
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.804 0.196
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.804 0.196
E63.9 Nutritional deficiency, unspecified
0.000 0.804 0.196
E63.8 Other specified nutritional deficiencies
0.000 0.804 0.196
E63.1 Imbalance of constituents of food intake
0.000 0.804 0.196
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.804 0.196
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.804 0.196
E64.8 Sequelae of other nutritional deficiencies
0.000 0.804 0.196
E64.3 Sequelae of rickets
0.000 0.804 0.196
E64.2 Sequelae of vitamin C deficiency
0.000 0.804 0.196
E64.1 Sequelae of vitamin A deficiency
0.000 0.804 0.196
E64.0 Sequelae of protein-energy malnutrition
0.000 0.804 0.196
C24.0 Extrahepatic bile duct
0.000 0.806 0.194
E88.2 Lipomatosis, not elsewhere classified
0.000 0.807 0.192
E55.0 Rickets, active
0.000 0.810 0.190
E56.9 Vitamin deficiency, unspecified
0.000 0.814 0.186
E56.8 Deficiency of other vitamins
0.000 0.814 0.186
E56.0 Deficiency of vitamin E
0.000 0.814 0.186
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.814 0.186
E75.2 Other sphingolipidosis
0.001 0.815 0.185
C21 Malignant neoplasm of anus and anal canal
0.000 0.816 0.183
C25.9 Pancreas, unspecified
0.000 0.817 0.183
E55.9 Vitamin D deficiency, unspecified
0.000 0.818 0.182
E75.6 Lipid storage disorder, unspecified
0.001 0.819 0.181
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.819 0.181
E75.3 Sphingolipidosis, unspecified
0.001 0.819 0.181
E75.1 Other gangliosidosis
0.001 0.819 0.181
E75.0 GM2 gangliosidosis
0.001 0.819 0.181
E83.8 Other disorders of mineral metabolism
0.117 0.819 0.064
E83.2 Disorders of zinc metabolism
0.117 0.819 0.064
E83.0 Disorders of copper metabolism
0.117 0.819 0.064
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.820 0.180
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.820 0.180
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.820 0.180
E74.2 Disorders of galactose metabolism
0.001 0.820 0.180
E74.1 Disorders of fructose metabolism
0.001 0.820 0.180
E83.9 Disorder of mineral metabolism, unspecified
0.116 0.821 0.062
I83 Varicose veins of lower extremities
0.178 0.822 0.000
E74.0 Glycogen storage disease
0.001 0.824 0.176
E73.9 Lactose intolerance, unspecified
0.000 0.824 0.175
E85.3 Secondary systemic amyloidosis
0.000 0.826 0.173
E85.8 Other amyloidosis
0.001 0.827 0.172
E56.1 Deficiency of vitamin K
0.000 0.828 0.172
E11.5 With peripheral circulatory complications
0.000 0.829 0.171
E88.8 Other specified metabolic disorders
0.000 0.830 0.170
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.830 0.170
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.830 0.170
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.830 0.170
E73.8 Other lactose intolerance
0.001 0.831 0.169
E73.1 Secondary lactase deficiency
0.001 0.831 0.169
E73.0 Congenital lactase deficiency
0.001 0.831 0.169
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.831 0.169
M45.X9 Ankylosing spondylitis (Site unspecified)
0.166 0.834 0.000
E71.3 Disorders of fatty-acid metabolism
0.001 0.835 0.164
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.835 0.164
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.835 0.164
E71.0 Maple-syrup-urine disease
0.001 0.835 0.164
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.835 0.164
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.835 0.164
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.835 0.164
E76.2 Other mucopolysaccharidoses
0.001 0.835 0.164
E76.1 Mucopolysaccharidosis, type II
0.001 0.835 0.164
E76.0 Mucopolysaccharidosis, type I
0.001 0.835 0.164
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.835 0.164
E77.8 Other disorders of glycoprotein metabolism
0.001 0.835 0.164
E77.1 Defects in glycoprotein degradation
0.001 0.835 0.164
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.835 0.164
E84.9 Cystic fibrosis, unspecified
0.001 0.837 0.163
E84.8 Cystic fibrosis with other manifestations
0.001 0.837 0.163
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.837 0.163
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.839 0.160
E65 Localised adiposity
0.000 0.840 0.160
C25.7 Other parts of pancreas
0.000 0.840 0.160
E67.8 Other specified hyperalimentation
0.000 0.841 0.159
E67.3 Hypervitaminosis D
0.000 0.841 0.159
E67.2 Megavitamin-B6 syndrome
0.000 0.841 0.159
E67.1 Hypercarotenaemia
0.000 0.841 0.159
E67.0 Hypervitaminosis A
0.000 0.841 0.159
E83.3 Disorders of phosphorus metabolism
0.135 0.841 0.024
C17.8 Overlapping lesion of small intestine
0.000 0.843 0.157
C17.3 Meckel's diverticulum
0.000 0.843 0.157
C24.8 Overlapping lesion of biliary tract
0.000 0.844 0.156
E53.9 Vitamin B deficiency, unspecified
0.000 0.844 0.155
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.845 0.154
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.845 0.154
E79.1 Lesch-Nyhan syndrome
0.001 0.845 0.154
E11.3 With ophthalmic complications
0.000 0.847 0.153
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.847 0.152
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.847 0.152
E70.2 Disorders of tyrosine metabolism
0.001 0.847 0.152
E70.1 Other hyperphenylalaninaemias
0.001 0.847 0.152
E70.0 Classical phenylketonuria
0.001 0.847 0.152
K90.9 Intestinal malabsorption, unspecified
0.000 0.847 0.152
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.849 0.150
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.849 0.150
E72.5 Disorders of glycine metabolism
0.001 0.849 0.150
E72.4 Disorders of ornithine metabolism
0.001 0.849 0.150
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.849 0.150
E72.2 Disorders of urea cycle metabolism
0.001 0.849 0.150
C24.9 Biliary tract, unspecified
0.000 0.849 0.151
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.850 0.150
E61.9 Deficiency of nutrient element, unspecified
0.000 0.851 0.149
E61.8 Deficiency of other specified nutrient elements
0.000 0.851 0.149
E61.7 Deficiency of multiple nutrient elements
0.000 0.851 0.149
E61.6 Vanadium deficiency
0.000 0.851 0.149
E61.5 Molybdenum deficiency
0.000 0.851 0.149
E61.4 Chromium deficiency
0.000 0.851 0.149
E61.3 Manganese deficiency
0.000 0.851 0.149
E61.0 Copper deficiency
0.000 0.851 0.149
E88.3 Tumour lysis syndrome
0.000 0.851 0.149
E72.0 Disorders of amino-acid transport
0.001 0.852 0.147
E06.3 Autoimmune thyroiditis
0.001 0.854 0.146
E53.1 Pyridoxine deficiency
0.000 0.856 0.144
E53.0 Riboflavin deficiency
0.000 0.856 0.144
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.856 0.144
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.859 0.141
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.862 0.138
C23 Malignant neoplasm of gallbladder
0.000 0.862 0.137
E70.3 Albinism
0.001 0.864 0.136
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.864 0.135
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.864 0.135
C17.1 Jejunum
0.000 0.865 0.135
E61.2 Magnesium deficiency
0.000 0.866 0.134
C21.2 Cloacogenic zone
0.000 0.868 0.132
E78.8 Other disorders of lipoprotein metabolism
0.000 0.875 0.125
I83.0 Varicose veins of lower extremities with ulcer
0.125 0.875 0.000
E85.9 Amyloidosis, unspecified
0.001 0.881 0.118
E20-E35 Disorders of other endocrine glands
0.000 0.883 0.117
C21.1 Anal canal
0.000 0.886 0.114
C22.1 Intrahepatic bile duct carcinoma
0.000 0.887 0.113
E61.1 Iron deficiency
0.000 0.890 0.110
C17.9 Small intestine, unspecified
0.000 0.891 0.108
C17.2 Ileum
0.000 0.892 0.108
C22.7 Other specified carcinomas of liver
0.000 0.892 0.107
C22.4 Other sarcomas of liver
0.000 0.892 0.107
C22.3 Angiosarcoma of liver
0.000 0.892 0.107
C22.2 Hepatoblastoma
0.000 0.892 0.107
C22.9 Liver, unspecified
0.000 0.893 0.106
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.106 0.894 0.000
C21.0 Anus, unspecified
0.000 0.894 0.106
E80.2 Other porphyria
0.001 0.895 0.104
E24 Cushing's syndrome
0.000 0.898 0.102
C26.8 Overlapping lesion of digestive system
0.000 0.901 0.099
C26.1 Spleen
0.000 0.901 0.099
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.902 0.097
E80.5 Crigler-Najjar syndrome
0.001 0.902 0.097
E80.3 Defects of catalase and peroxydase
0.001 0.902 0.097
E80.0 Hereditary erythropoietic porphyria
0.001 0.902 0.097
E83.4 Disorders of magnesium metabolism
0.055 0.906 0.039
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.909 0.091
C16 Malignant neoplasm of stomach
0.000 0.910 0.090
E11.4 With neurological complications
0.000 0.911 0.089
C18 Malignant neoplasm of colon
0.000 0.912 0.088
E20 Hypoparathyroidism
0.000 0.913 0.087
M45 Ankylosing spondylitis
0.087 0.913 0.000
C18.1 Appendix
0.000 0.914 0.086
E28 Ovarian dysfunction
0.000 0.914 0.086
E21.3 Hyperparathyroidism, unspecified
0.000 0.915 0.085
C24.1 Ampulla of Vater
0.001 0.915 0.084
E80.6 Other disorders of bilirubin metabolism
0.001 0.916 0.084
E25 Adrenogenital disorders
0.000 0.916 0.084
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.916 0.084
E32 Diseases of thymus
0.000 0.916 0.084
E30 Disorders of puberty, not elsewhere classified
0.000 0.916 0.084
C18.9 Colon, unspecified
0.000 0.917 0.083
E24.0 Pituitary-dependent Cushing's disease
0.000 0.917 0.083
E31 Polyglandular dysfunction
0.000 0.917 0.083
E80.1 Porphyria cutanea tarda
0.001 0.918 0.081
E24.9 Cushing's syndrome, unspecified
0.000 0.919 0.081
I83.1 Varicose veins of lower extremities with inflammation
0.078 0.922 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.922 0.078
E24.8 Other Cushing's syndrome
0.000 0.925 0.074
E83.5 Disorders of calcium metabolism
0.005 0.926 0.069
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.927 0.073
E24.3 Ectopic ACTH syndrome
0.000 0.927 0.073
E24.1 Nelson's syndrome
0.000 0.927 0.073
C26.9 Ill-defined sites within the digestive system
0.001 0.928 0.072
E78.0 Pure hypercholesterolaemia
0.000 0.928 0.072
C26.0 Intestinal tract, part unspecified
0.000 0.929 0.071
E29 Testicular dysfunction
0.000 0.929 0.071
M45.X6 Ankylosing spondylitis (Lumbar region)
0.069 0.931 0.000
E34 Other endocrine disorders
0.000 0.931 0.069
C16.0 Cardia
0.000 0.931 0.069
M45.X2 Ankylosing spondylitis (Cervical region)
0.068 0.932 0.000
E21.2 Other hyperparathyroidism
0.000 0.934 0.066
E20.9 Hypoparathyroidism, unspecified
0.000 0.934 0.065
E21.4 Other specified disorders of parathyroid gland
0.000 0.934 0.065
C16.5 Lesser curvature of stomach, unspecified
0.000 0.935 0.065
E28.2 Polycystic ovarian syndrome
0.000 0.935 0.065
C18.8 Overlapping lesion of colon
0.000 0.936 0.064
C16.2 Body of stomach
0.000 0.937 0.063
C25.0 Head of pancreas
0.000 0.937 0.063
E20.8 Other hypoparathyroidism
0.000 0.937 0.062
E20.1 Pseudohypoparathyroidism
0.000 0.937 0.062
E20.0 Idiopathic hypoparathyroidism
0.000 0.937 0.062
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.063 0.937 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.063 0.937 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.063 0.937 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.063 0.937 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.063 0.937 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.063 0.937 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.938 0.062
E28.8 Other ovarian dysfunction
0.000 0.938 0.062
E28.1 Androgen excess
0.000 0.938 0.062
E28.0 Oestrogen excess
0.000 0.938 0.062
C16.6 Greater curvature of stomach, unspecified
0.000 0.938 0.061
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.061 0.939 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.939 0.061
E25.9 Adrenogenital disorder, unspecified
0.000 0.939 0.060
E25.8 Other adrenogenital disorders
0.000 0.939 0.060
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.939 0.060
E30.9 Disorder of puberty, unspecified
0.000 0.939 0.060
E30.8 Other disorders of puberty
0.000 0.939 0.060
E30.1 Precocious puberty
0.000 0.939 0.060
E30.0 Delayed puberty
0.000 0.939 0.060
E32.9 Disease of thymus, unspecified
0.000 0.939 0.060
E32.8 Other diseases of thymus
0.000 0.939 0.060
E32.1 Abscess of thymus
0.000 0.939 0.060
E32.0 Persistent hyperplasia of thymus
0.000 0.939 0.060
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.939 0.060
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.939 0.060
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.939 0.060
E28.3 Primary ovarian failure
0.000 0.940 0.060
E31.9 Polyglandular dysfunction, unspecified
0.000 0.940 0.059
E31.8 Other polyglandular dysfunction
0.000 0.940 0.059
E31.1 Polyglandular hyperfunction
0.000 0.940 0.059
E31.0 Autoimmune polyglandular failure
0.000 0.942 0.058
C16.8 Overlapping lesion of stomach
0.000 0.942 0.058
C16.4 Pylorus
0.000 0.943 0.057
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.056 0.944 0.000
C16.9 Stomach, unspecified
0.000 0.945 0.055
E26 Hyperaldosteronism
0.000 0.945 0.054
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.946 0.054
I86 Varicose veins of other sites
0.054 0.946 0.000
C18.3 Hepatic flexure
0.000 0.948 0.052
E80.4 Gilbert's syndrome
0.000 0.948 0.052
C16.1 Fundus of stomach
0.000 0.949 0.051
C16.3 Pyloric antrum
0.000 0.949 0.051
C18.6 Descending colon
0.000 0.949 0.051
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.051 0.949 0.000
E29.8 Other testicular dysfunction
0.000 0.949 0.051
E29.0 Testicular hyperfunction
0.000 0.949 0.051
I81 Portal vein thrombosis
0.051 0.949 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.949 0.050
I89.0 Lymphoedema, not elsewhere classified
0.050 0.950 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.950 0.050
C18.4 Transverse colon
0.000 0.950 0.050
E34.5 Androgen resistance syndrome
0.000 0.950 0.049
E34.4 Constitutional tall stature
0.000 0.950 0.049
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.950 0.049
E34.1 Other hypersecretion of intestinal hormones
0.000 0.950 0.049
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.049 0.951 0.000
I86.8 Varicose veins of other specified sites
0.049 0.951 0.000
E34.8 Other specified endocrine disorders
0.000 0.953 0.047
E21.0 Primary hyperparathyroidism
0.000 0.954 0.046
E86 Volume depletion
0.000 0.954 0.046
E03.9 Hypothyroidism, unspecified
0.000 0.954 0.046
E04 Other non-toxic goitre
0.002 0.954 0.044
E34.9 Endocrine disorder, unspecified
0.000 0.955 0.045
E22 Hyperfunction of pituitary gland
0.000 0.955 0.045
I86.4 Gastric varices
0.044 0.956 0.000
I89.1 Lymphangitis
0.044 0.956 0.000
I85 Oesophageal varices
0.044 0.956 0.000
I82 Other venous embolism and thrombosis
0.043 0.957 0.000
I77 Other disorders of arteries and arterioles
0.000 0.957 0.043
E23 Hypofunction and other disorders of pituitary gland
0.000 0.957 0.043
I77.6 Arteritis, unspecified
0.000 0.957 0.043
E34.0 Carcinoid syndrome
0.000 0.958 0.042
I73 Other peripheral vascular diseases
0.000 0.958 0.042
I87 Other disorders of veins
0.042 0.958 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.958 0.042
I86.2 Pelvic varices
0.041 0.959 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.960 0.040
I86.3 Vulval varices
0.040 0.960 0.000
E26.8 Other hyperaldosteronism
0.000 0.961 0.039
E26.1 Secondary hyperaldosteronism
0.000 0.961 0.039
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.961 0.039
E29.1 Testicular hypofunction
0.000 0.961 0.039
I86.0 Sublingual varices
0.039 0.961 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.961 0.038
I77.8 Other specified disorders of arteries and arterioles
0.000 0.962 0.038
I73.0 Raynaud's syndrome
0.000 0.963 0.037
R31 Unspecified haematuria
0.037 0.963 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.963 0.037
I88 Nonspecific lymphadenitis
0.037 0.963 0.000
I85.9 Oesophageal varices without bleeding
0.036 0.964 0.000
I74 Arterial embolism and thrombosis
0.000 0.965 0.035
I82.8 Embolism and thrombosis of other specified veins
0.035 0.965 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.965 0.034
I87.8 Other specified disorders of veins
0.035 0.965 0.000
I82.0 Budd-Chiari syndrome
0.034 0.965 0.000
I72 Other aneurysm
0.000 0.965 0.035
C18.7 Sigmoid colon
0.000 0.966 0.034
C22.0 Liver cell carcinoma
0.001 0.966 0.033
I77.3 Arterial fibromuscular dysplasia
0.000 0.967 0.033
I73.8 Other specified peripheral vascular diseases
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.031
E22.8 Other hyperfunction of pituitary gland
0.000 0.968 0.032
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.968 0.032
I70 Atherosclerosis
0.000 0.968 0.032

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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