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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs209164
log Bayes Factor = 52.032
Chromosome 6   position 28,836,456  (GRCh37) Explore rs209164 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.010 0.990
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.014 0.986
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.015 0.985
E16 Other disorders of pancreatic internal secretion
0.000 0.015 0.985
E16.2 Hypoglycaemia, unspecified
0.000 0.016 0.984
E00-E07 Disorders of thyroid gland
0.000 0.018 0.982
E10.2 With renal complications
0.000 0.040 0.960
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.100 0.900
E10.4 With neurological complications
0.000 0.101 0.899
E10.1 With ketoacidosis
0.000 0.101 0.899
E05.8 Other thyrotoxicosis
0.000 0.161 0.839
E13 Other specified diabetes mellitus
0.000 0.198 0.802
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.207 0.793
E16.1 Other hypoglycaemia
0.000 0.220 0.780
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.740 0.260 0.000
E10.0 With coma
0.000 0.266 0.733
E14 Unspecified diabetes mellitus
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.275 0.724
E05.5 Thyroid crisis or storm
0.000 0.290 0.710
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.710
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.710
E12 Malnutrition-related diabetes mellitus
0.000 0.290 0.710
E15 Nondiabetic hypoglycaemic coma
0.000 0.294 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.294 0.706
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.294 0.706
E16.4 Abnormal secretion of gastrin
0.000 0.294 0.706
E16.3 Increased secretion of glucagon
0.000 0.294 0.706
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.296 0.704
E00 Congenital iodine-deficiency syndrome
0.000 0.296 0.704
E40-E46 Malnutrition
0.000 0.320 0.680
E13.9 Without complications
0.000 0.338 0.662
E10.6 With other specified complications
0.000 0.349 0.651
E14.3 With ophthalmic complications
0.000 0.357 0.643
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.365 0.635
E10.5 With peripheral circulatory complications
0.000 0.375 0.624
E07 Other disorders of thyroid
0.000 0.379 0.621
E10.8 With unspecified complications
0.000 0.416 0.584
E13.3 With ophthalmic complications
0.000 0.418 0.582
E13.8 With unspecified complications
0.000 0.425 0.575
E13.7 With multiple complications
0.000 0.425 0.575
E13.6 With other specified complications
0.000 0.425 0.575
E13.5 With peripheral circulatory complications
0.000 0.425 0.575
E13.4 With neurological complications
0.000 0.425 0.575
E13.2 With renal complications
0.000 0.425 0.575
E13.1 With ketoacidosis
0.000 0.425 0.575
E13.0 With coma
0.000 0.425 0.575
E14.1 With ketoacidosis
0.000 0.428 0.572
E06 Thyroiditis
0.000 0.432 0.568
E14.6 With other specified complications
0.000 0.445 0.555
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.455 0.545
E14.4 With neurological complications
0.000 0.474 0.526
E14.7 With multiple complications
0.000 0.480 0.520
E14.5 With peripheral circulatory complications
0.000 0.483 0.517
E14.8 With unspecified complications
0.000 0.489 0.511
E12.9 Without complications
0.000 0.491 0.509
E12.8 With unspecified complications
0.000 0.491 0.509
E12.7 With multiple complications
0.000 0.491 0.509
E12.6 With other specified complications
0.000 0.491 0.509
E12.5 With peripheral circulatory complications
0.000 0.491 0.509
E12.4 With neurological complications
0.000 0.491 0.509
E12.3 With ophthalmic complications
0.000 0.491 0.509
E12.2 With renal complications
0.000 0.491 0.509
E12.1 With ketoacidosis
0.000 0.491 0.509
E12.0 With coma
0.000 0.491 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.495 0.505
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.495 0.505
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.495 0.505
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.495 0.505
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.495 0.505
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.495 0.505
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.495 0.505
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.495 0.505
E14.2 Withrenal complications
0.000 0.500 0.499
E14.0 With coma
0.000 0.511 0.488
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.512 0.487
E45 Retarded development following protein-energy malnutrition
0.000 0.512 0.487
E43 Unspecified severe protein-energy malnutrition
0.000 0.512 0.487
E42 Marasmic kwashiorkor
0.000 0.512 0.487
E41 Nutritional marasmus
0.000 0.512 0.487
E40 Kwashiorkor
0.000 0.512 0.487
E07.8 Other specified disorders of thyroid
0.000 0.514 0.486
E46 Unspecified protein-energy malnutrition
0.000 0.540 0.460
E06.9 Thyroiditis, unspecified
0.000 0.545 0.454
E07.1 Dyshormogenetic goitre
0.000 0.555 0.445
E07.0 Hypersecretion of calcitonin
0.000 0.555 0.445
E06.1 Subacute thyroiditis
0.000 0.571 0.428
E06.4 Drug-induced thyroiditis
0.000 0.593 0.407
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.593 0.407
E06.0 Acute thyroiditis
0.000 0.593 0.407
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.616 0.384
E50-E64 Other nutritional deficiencies
0.000 0.623 0.377
E06.5 Other chronic thyroiditis
0.000 0.624 0.376
K90 Intestinal malabsorption
0.000 0.634 0.366
E03 Other hypothyroidism
0.000 0.648 0.352
E44.1 Mild protein-energy malnutrition
0.000 0.650 0.349
E44.0 Moderate protein-energy malnutrition
0.000 0.650 0.349
E65-E68 Obesity and other hyperalimentation
0.000 0.694 0.305
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.696 0.304
E70-E90 Metabolic disorders
0.001 0.709 0.290
E11 Non-insulin-dependent diabetes mellitus
0.000 0.709 0.291
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.715 0.285
E07.9 Disorder of thyroid, unspecified
0.000 0.717 0.283
E78.2 Mixed hyperlipidaemia
0.000 0.723 0.277
E54 Ascorbic acid deficiency
0.000 0.724 0.276
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.729 0.271
E63 Other nutritional deficiencies
0.000 0.729 0.271
E50 Vitamin A deficiency
0.000 0.729 0.271
E60 Dietary zinc deficiency
0.000 0.729 0.271
E59 Dietary selenium deficiency
0.000 0.729 0.271
E52 Niacin deficiency [pellagra]
0.000 0.729 0.271
E51 Thiamine deficiency
0.000 0.729 0.271
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.735 0.265
K90.3 Pancreatic steatorrhoea
0.000 0.738 0.262
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.738 0.262
K90.1 Tropical sprue
0.000 0.738 0.262
E11.6 With other specified complications
0.000 0.739 0.261
E56 Other vitamin deficiencies
0.000 0.743 0.257
E55 Vitamin D deficiency
0.000 0.745 0.255
K90.8 Other intestinal malabsorption
0.000 0.746 0.254
E03.5 Myxoedema coma
0.000 0.747 0.253
E03.4 Atrophy of thyroid (acquired)
0.000 0.747 0.253
E03.3 Postinfectious hypothyroidism
0.000 0.747 0.253
E78.5 Hyperlipidaemia, unspecified
0.000 0.748 0.252
E11.1 With ketoacidosis
0.000 0.748 0.251
E83 Disorders of mineral metabolism
0.164 0.749 0.087
E78.1 Pure hyperglyceridaemia
0.000 0.753 0.247
E03.1 Congenital hypothyroidism without goitre
0.000 0.755 0.245
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.763 0.237
E58 Dietary calcium deficiency
0.000 0.763 0.237
E88 Other metabolic disorders
0.000 0.763 0.236
E78.6 Lipoprotein deficiency
0.000 0.769 0.231
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.770 0.229
E74 Other disorders of carbohydrate metabolism
0.001 0.772 0.227
E11.0 With coma
0.000 0.772 0.227
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.776 0.224
E11.2 With renal complications
0.000 0.778 0.221
E61 Deficiency of other nutrient elements
0.000 0.780 0.220
E67 Other hyperalimentation
0.000 0.781 0.219
E68 Sequelae of hyperalimentation
0.000 0.781 0.219
E78.3 Hyperchylomicronaemia
0.000 0.784 0.216
I83 Varicose veins of lower extremities
0.215 0.785 0.000
E03.8 Other specified hypothyroidism
0.000 0.786 0.214
E85 Amyloidosis
0.001 0.787 0.213
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.787 0.213
E77 Disorders of glycoprotein metabolism
0.001 0.791 0.208
E76 Disorders of glycosaminoglycan metabolism
0.001 0.791 0.208
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.791 0.208
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.791 0.208
E11.7 With multiple complications
0.000 0.791 0.209
E73 Lactose intolerance
0.001 0.793 0.207
E84 Cystic fibrosis
0.001 0.793 0.206
E70 Disorders of aromatic amino-acid metabolism
0.001 0.795 0.204
E88.9 Metabolic disorder, unspecified
0.000 0.800 0.200
E79 Disorders of purine and pyrimidine metabolism
0.001 0.804 0.195
E53 Deficiency of other B group vitamins
0.000 0.804 0.196
E50.9 Vitamin A deficiency, unspecified
0.000 0.806 0.194
E50.8 Other manifestations of vitamin A deficiency
0.000 0.806 0.194
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.806 0.194
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.806 0.194
E50.5 Vitamin A deficiency with night blindness
0.000 0.806 0.194
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.806 0.194
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.806 0.194
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.806 0.194
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.806 0.194
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.806 0.194
E63.9 Nutritional deficiency, unspecified
0.000 0.806 0.194
E63.8 Other specified nutritional deficiencies
0.000 0.806 0.194
E63.1 Imbalance of constituents of food intake
0.000 0.806 0.194
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.806 0.194
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.806 0.194
E64.8 Sequelae of other nutritional deficiencies
0.000 0.806 0.194
E64.3 Sequelae of rickets
0.000 0.806 0.194
E64.2 Sequelae of vitamin C deficiency
0.000 0.806 0.194
E64.1 Sequelae of vitamin A deficiency
0.000 0.806 0.194
E64.0 Sequelae of protein-energy malnutrition
0.000 0.806 0.194
E51.9 Thiamine deficiency, unspecified
0.000 0.806 0.194
E51.8 Other manifestations of thiamine deficiency
0.000 0.806 0.194
E51.1 Beriberi
0.000 0.806 0.194
E51.2 Wernicke's encephalopathy
0.000 0.806 0.194
C15 Malignant neoplasm of oesophagus
0.000 0.808 0.192
C15-C26 Malignant neoplasms of digestive organs
0.000 0.809 0.191
E72 Other disorders of amino-acid metabolism
0.001 0.809 0.190
C20 Malignant neoplasm of rectum
0.000 0.810 0.190
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.812 0.188
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.815 0.184
E56.9 Vitamin deficiency, unspecified
0.000 0.816 0.184
E56.8 Deficiency of other vitamins
0.000 0.816 0.184
E56.0 Deficiency of vitamin E
0.000 0.816 0.184
E75.5 Other lipid storage disorders
0.000 0.817 0.183
E55.0 Rickets, active
0.000 0.817 0.183
E88.2 Lipomatosis, not elsewhere classified
0.000 0.818 0.182
E78.4 Other hyperlipidaemia
0.000 0.818 0.182
E83.8 Other disorders of mineral metabolism
0.117 0.820 0.063
E83.2 Disorders of zinc metabolism
0.117 0.820 0.063
E83.0 Disorders of copper metabolism
0.117 0.820 0.063
E85.4 Organ-limited amyloidosis
0.000 0.821 0.179
E11.8 With unspecified complications
0.000 0.822 0.178
E83.9 Disorder of mineral metabolism, unspecified
0.117 0.822 0.061
C15.9 Oesophagus, unspecified
0.000 0.828 0.172
C15.5 Lower third of oesophagus
0.000 0.828 0.172
C15.4 Middle third of oesophagus
0.000 0.828 0.172
E56.1 Deficiency of vitamin K
0.000 0.830 0.170
E75.2 Other sphingolipidosis
0.001 0.832 0.167
E55.9 Vitamin D deficiency, unspecified
0.000 0.833 0.167
E75.6 Lipid storage disorder, unspecified
0.001 0.835 0.164
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.835 0.164
E75.3 Sphingolipidosis, unspecified
0.001 0.835 0.164
E75.1 Other gangliosidosis
0.001 0.835 0.164
E75.0 GM2 gangliosidosis
0.001 0.835 0.164
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.837 0.163
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.837 0.163
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.837 0.163
E74.2 Disorders of galactose metabolism
0.001 0.837 0.163
E74.1 Disorders of fructose metabolism
0.001 0.837 0.163
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.838 0.162
E88.8 Other specified metabolic disorders
0.000 0.839 0.161
C25 Malignant neoplasm of pancreas
0.000 0.840 0.160
E83.3 Disorders of phosphorus metabolism
0.137 0.840 0.023
E06.3 Autoimmune thyroiditis
0.000 0.840 0.159
E74.0 Glycogen storage disease
0.001 0.841 0.159
E61.9 Deficiency of nutrient element, unspecified
0.000 0.842 0.158
E61.8 Deficiency of other specified nutrient elements
0.000 0.842 0.158
E61.7 Deficiency of multiple nutrient elements
0.000 0.842 0.158
E61.6 Vanadium deficiency
0.000 0.842 0.158
E61.5 Molybdenum deficiency
0.000 0.842 0.158
E61.4 Chromium deficiency
0.000 0.842 0.158
E61.3 Manganese deficiency
0.000 0.842 0.158
E61.0 Copper deficiency
0.000 0.842 0.158
E67.8 Other specified hyperalimentation
0.000 0.843 0.157
E67.3 Hypervitaminosis D
0.000 0.843 0.157
E67.2 Megavitamin-B6 syndrome
0.000 0.843 0.157
E67.1 Hypercarotenaemia
0.000 0.843 0.157
E67.0 Hypervitaminosis A
0.000 0.843 0.157
E85.3 Secondary systemic amyloidosis
0.001 0.844 0.155
E65 Localised adiposity
0.000 0.844 0.156
E85.8 Other amyloidosis
0.001 0.845 0.154
K90.9 Intestinal malabsorption, unspecified
0.000 0.846 0.154
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.847 0.152
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.847 0.152
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.847 0.152
E53.9 Vitamin B deficiency, unspecified
0.000 0.848 0.152
E71.3 Disorders of fatty-acid metabolism
0.001 0.850 0.149
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.850 0.149
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.850 0.149
E71.0 Maple-syrup-urine disease
0.001 0.850 0.149
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.850 0.149
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.850 0.149
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.850 0.149
E76.2 Other mucopolysaccharidoses
0.001 0.850 0.149
E76.1 Mucopolysaccharidosis, type II
0.001 0.850 0.149
E76.0 Mucopolysaccharidosis, type I
0.001 0.850 0.149
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.850 0.149
E77.8 Other disorders of glycoprotein metabolism
0.001 0.850 0.149
E77.1 Defects in glycoprotein degradation
0.001 0.850 0.149
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.850 0.149
C15.0 Cervical part of oesophagus
0.000 0.851 0.149
E73.8 Other lactose intolerance
0.001 0.851 0.148
E73.1 Secondary lactase deficiency
0.001 0.851 0.148
E73.0 Congenital lactase deficiency
0.001 0.851 0.148
E84.8 Cystic fibrosis with other manifestations
0.001 0.852 0.148
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.852 0.148
E84.9 Cystic fibrosis, unspecified
0.001 0.852 0.148
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.853 0.146
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.853 0.146
E70.2 Disorders of tyrosine metabolism
0.001 0.853 0.146
E70.1 Other hyperphenylalaninaemias
0.001 0.853 0.146
E70.0 Classical phenylketonuria
0.001 0.853 0.146
E73.9 Lactose intolerance, unspecified
0.000 0.853 0.146
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.854 0.145
C17 Malignant neoplasm of small intestine
0.000 0.855 0.145
E11.5 With peripheral circulatory complications
0.000 0.855 0.145
I83.0 Varicose veins of lower extremities with ulcer
0.144 0.856 0.000
E70.3 Albinism
0.001 0.857 0.142
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.858 0.142
C15.3 Upper third of oesophagus
0.000 0.858 0.142
E88.3 Tumour lysis syndrome
0.000 0.859 0.141
E61.2 Magnesium deficiency
0.000 0.859 0.141
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.859 0.140
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.859 0.140
E79.1 Lesch-Nyhan syndrome
0.001 0.859 0.140
E53.1 Pyridoxine deficiency
0.000 0.859 0.141
E53.0 Riboflavin deficiency
0.000 0.859 0.141
C15.1 Thoracic part of oesophagus
0.000 0.860 0.140
C17.0 Duodenum
0.000 0.862 0.138
C15.8 Overlapping lesion of oesophagus
0.000 0.862 0.138
C15.2 Abdominal part of oesophagus
0.000 0.862 0.138
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.863 0.137
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.863 0.137
E72.5 Disorders of glycine metabolism
0.001 0.863 0.137
E72.4 Disorders of ornithine metabolism
0.001 0.863 0.137
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.863 0.137
E72.2 Disorders of urea cycle metabolism
0.001 0.863 0.137
E72.0 Disorders of amino-acid transport
0.001 0.866 0.133
C25.2 Tail of pancreas
0.000 0.866 0.134
C25.3 Pancreatic duct
0.000 0.866 0.134
C25.1 Body of pancreas
0.000 0.868 0.132
E14.9 Without complications
0.000 0.869 0.131
E61.1 Iron deficiency
0.000 0.869 0.131
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.129 0.870 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.872 0.127
C24.0 Extrahepatic bile duct
0.000 0.873 0.127
C25.8 Overlapping lesion of pancreas
0.000 0.875 0.125
C25.4 Endocrine pancreas
0.000 0.875 0.125
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.876 0.123
C21 Malignant neoplasm of anus and anal canal
0.000 0.877 0.123
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.877 0.122
E78.8 Other disorders of lipoprotein metabolism
0.000 0.889 0.111
C25.9 Pancreas, unspecified
0.000 0.890 0.110
E11.3 With ophthalmic complications
0.000 0.894 0.106
E85.9 Amyloidosis, unspecified
0.001 0.894 0.105
E20-E35 Disorders of other endocrine glands
0.000 0.894 0.106
C17.8 Overlapping lesion of small intestine
0.000 0.896 0.104
C17.3 Meckel's diverticulum
0.000 0.896 0.104
C24.8 Overlapping lesion of biliary tract
0.000 0.898 0.102
I83.1 Varicose veins of lower extremities with inflammation
0.102 0.898 0.000
C25.7 Other parts of pancreas
0.000 0.899 0.100
C24.9 Biliary tract, unspecified
0.000 0.902 0.098
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.904 0.096
E80.2 Other porphyria
0.001 0.906 0.094
E24 Cushing's syndrome
0.000 0.906 0.094
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.907 0.093
E83.4 Disorders of magnesium metabolism
0.053 0.907 0.040
C23 Malignant neoplasm of gallbladder
0.000 0.907 0.093
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.092 0.908 0.000
C17.1 Jejunum
0.000 0.910 0.090
C21.2 Cloacogenic zone
0.000 0.912 0.088
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.912 0.087
E80.5 Crigler-Najjar syndrome
0.001 0.912 0.087
E80.3 Defects of catalase and peroxydase
0.001 0.912 0.087
E80.0 Hereditary erythropoietic porphyria
0.001 0.912 0.087
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.912 0.088
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.086 0.914 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.915 0.085
I86 Varicose veins of other sites
0.083 0.917 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.082 0.918 0.000
I89.0 Lymphoedema, not elsewhere classified
0.079 0.921 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.921 0.079
C21.1 Anal canal
0.000 0.921 0.078
E25 Adrenogenital disorders
0.000 0.922 0.078
E20 Hypoparathyroidism
0.000 0.922 0.078
E24.0 Pituitary-dependent Cushing's disease
0.000 0.923 0.076
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.924 0.076
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.924 0.076
E32 Diseases of thymus
0.000 0.924 0.076
E30 Disorders of puberty, not elsewhere classified
0.000 0.924 0.076
I81 Portal vein thrombosis
0.076 0.924 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.076 0.924 0.000
E80.6 Other disorders of bilirubin metabolism
0.001 0.924 0.075
I86.8 Varicose veins of other specified sites
0.075 0.925 0.000
E31 Polyglandular dysfunction
0.000 0.925 0.075
E83.5 Disorders of calcium metabolism
0.005 0.925 0.070
E28 Ovarian dysfunction
0.000 0.926 0.074
E80.1 Porphyria cutanea tarda
0.001 0.926 0.073
C21.0 Anus, unspecified
0.000 0.927 0.073
E24.2 Drug-induced Cushing's syndrome
0.000 0.928 0.072
C17.9 Small intestine, unspecified
0.000 0.928 0.071
C17.2 Ileum
0.000 0.929 0.071
E21.3 Hyperparathyroidism, unspecified
0.000 0.929 0.071
C22.1 Intrahepatic bile duct carcinoma
0.000 0.931 0.069
I86.4 Gastric varices
0.069 0.931 0.000
I89.1 Lymphangitis
0.068 0.931 0.000
E24.8 Other Cushing's syndrome
0.000 0.932 0.067
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.932 0.067
E24.3 Ectopic ACTH syndrome
0.000 0.932 0.067
E24.1 Nelson's syndrome
0.000 0.932 0.067
C22.7 Other specified carcinomas of liver
0.000 0.933 0.067
C22.4 Other sarcomas of liver
0.000 0.933 0.067
C22.3 Angiosarcoma of liver
0.000 0.933 0.067
C22.2 Hepatoblastoma
0.000 0.933 0.067
I82 Other venous embolism and thrombosis
0.066 0.934 0.000
I85 Oesophageal varices
0.066 0.934 0.000
C22.9 Liver, unspecified
0.000 0.934 0.065
E29 Testicular dysfunction
0.000 0.935 0.065
E34 Other endocrine disorders
0.000 0.937 0.063
C26.8 Overlapping lesion of digestive system
0.000 0.937 0.063
C26.1 Spleen
0.000 0.937 0.063
I86.2 Pelvic varices
0.063 0.937 0.000
C24.1 Ampulla of Vater
0.000 0.938 0.062
I87 Other disorders of veins
0.062 0.938 0.000
I86.3 Vulval varices
0.061 0.939 0.000
E11.4 With neurological complications
0.000 0.939 0.061
I86.0 Sublingual varices
0.059 0.940 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.941 0.059
E20.9 Hypoparathyroidism, unspecified
0.000 0.942 0.058
E25.9 Adrenogenital disorder, unspecified
0.000 0.944 0.056
E25.8 Other adrenogenital disorders
0.000 0.944 0.056
E20.8 Other hypoparathyroidism
0.000 0.944 0.056
E20.1 Pseudohypoparathyroidism
0.000 0.944 0.056
E20.0 Idiopathic hypoparathyroidism
0.000 0.944 0.056
E21.2 Other hyperparathyroidism
0.000 0.945 0.055
E03.9 Hypothyroidism, unspecified
0.000 0.945 0.055
E21.4 Other specified disorders of parathyroid gland
0.000 0.945 0.055
I82.8 Embolism and thrombosis of other specified veins
0.055 0.945 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.945 0.055
E30.8 Other disorders of puberty
0.000 0.945 0.055
E30.1 Precocious puberty
0.000 0.945 0.055
E30.0 Delayed puberty
0.000 0.945 0.055
E32.9 Disease of thymus, unspecified
0.000 0.945 0.055
E32.8 Other diseases of thymus
0.000 0.945 0.055
E32.1 Abscess of thymus
0.000 0.945 0.055
E32.0 Persistent hyperplasia of thymus
0.000 0.945 0.055
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.945 0.055
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.945 0.055
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.945 0.055
C16 Malignant neoplasm of stomach
0.000 0.945 0.054
E31.9 Polyglandular dysfunction, unspecified
0.000 0.946 0.054
E31.8 Other polyglandular dysfunction
0.000 0.946 0.054
E31.1 Polyglandular hyperfunction
0.000 0.946 0.054
I88 Nonspecific lymphadenitis
0.054 0.946 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.947 0.053
E28.8 Other ovarian dysfunction
0.000 0.947 0.053
E28.1 Androgen excess
0.000 0.947 0.053
E28.0 Oestrogen excess
0.000 0.947 0.053
E28.2 Polycystic ovarian syndrome
0.000 0.947 0.053
I85.9 Oesophageal varices without bleeding
0.053 0.947 0.000
I82.0 Budd-Chiari syndrome
0.053 0.947 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.947 0.052
I87.8 Other specified disorders of veins
0.052 0.948 0.000
E28.3 Primary ovarian failure
0.000 0.949 0.051
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.949 0.050
E26 Hyperaldosteronism
0.000 0.950 0.050
I82.1 Thrombophlebitis migrans
0.048 0.952 0.000
E29.8 Other testicular dysfunction
0.000 0.953 0.047
E29.0 Testicular hyperfunction
0.000 0.953 0.047
E80.4 Gilbert's syndrome
0.000 0.954 0.046
E34.3 Short stature, not elsewhere classified
0.000 0.954 0.046
C26.9 Ill-defined sites within the digestive system
0.000 0.954 0.045
E29.9 Testicular dysfunction, unspecified
0.000 0.954 0.046
E34.5 Androgen resistance syndrome
0.000 0.954 0.045
E34.4 Constitutional tall stature
0.000 0.954 0.045
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.954 0.045
E34.1 Other hypersecretion of intestinal hormones
0.000 0.954 0.045
E04 Other non-toxic goitre
0.002 0.954 0.043
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.955 0.045
C18 Malignant neoplasm of colon
0.000 0.955 0.045
I82.3 Embolism and thrombosis of renal vein
0.045 0.955 0.000
E86 Volume depletion
0.000 0.955 0.045
C18.1 Appendix
0.000 0.955 0.045
I87.0 Postphlebitic syndrome
0.044 0.955 0.000
C26.0 Intestinal tract, part unspecified
0.000 0.956 0.044
I87.9 Disorder of vein, unspecified
0.044 0.956 0.000
I82.2 Embolism and thrombosis of vena cava
0.044 0.956 0.000
M45 Ankylosing spondylitis
0.043 0.957 0.000
E34.8 Other specified endocrine disorders
0.000 0.957 0.043
E34.9 Endocrine disorder, unspecified
0.000 0.957 0.043
C18.9 Colon, unspecified
0.000 0.958 0.042
C16.0 Cardia
0.000 0.958 0.042
I86.1 Scrotal varices
0.041 0.959 0.000
C25.0 Head of pancreas
0.000 0.960 0.040
I87.2 Venous insufficiency (chronic) (peripheral)
0.040 0.960 0.000
C16.5 Lesser curvature of stomach, unspecified
0.000 0.961 0.039
E23 Hypofunction and other disorders of pituitary gland
0.000 0.961 0.039
E22 Hyperfunction of pituitary gland
0.000 0.961 0.039
I88.1 Chronic lymphadenitis, except mesenteric
0.039 0.961 0.000
I85.0 Oesophageal varices with bleeding
0.039 0.961 0.000
E34.0 Carcinoid syndrome
0.000 0.961 0.038
C16.2 Body of stomach
0.000 0.962 0.038
C16.6 Greater curvature of stomach, unspecified
0.000 0.963 0.037
E29.1 Testicular hypofunction
0.000 0.963 0.037
I82.9 Embolism and thrombosis of unspecified vein
0.037 0.963 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.036 0.963 0.000
E26.8 Other hyperaldosteronism
0.000 0.964 0.036
E26.1 Secondary hyperaldosteronism
0.000 0.964 0.036
I88.8 Other nonspecific lymphadenitis
0.035 0.965 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.965 0.035
C16.8 Overlapping lesion of stomach
0.000 0.965 0.035
M45.X6 Ankylosing spondylitis (Lumbar region)
0.035 0.965 0.000
C16.4 Pylorus
0.000 0.965 0.034
E21.0 Primary hyperparathyroidism
0.000 0.966 0.034
I88.9 Nonspecific lymphadenitis, unspecified
0.034 0.966 0.000
C18.8 Overlapping lesion of colon
0.000 0.966 0.034
I87.1 Compression of vein
0.034 0.966 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.966 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.031
M45.X2 Ankylosing spondylitis (Cervical region)
0.033 0.967 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.968 0.031
C16.9 Stomach, unspecified
0.000 0.968 0.032
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.031 0.969 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.031 0.969 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.031 0.969 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.031 0.969 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.031 0.969 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.031 0.969 0.000
C16.1 Fundus of stomach
0.000 0.969 0.031
C16.3 Pyloric antrum
0.000 0.969 0.031
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.030 0.970 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.972 0.028
E23.1 Drug-induced hypopituitarism
0.000 0.972 0.028
E22.8 Other hyperfunction of pituitary gland
0.000 0.972 0.028
I73 Other peripheral vascular diseases
0.000 0.972 0.028
I73.9 Peripheral vascular disease, unspecified
0.000 0.972 0.028
I77.6 Arteritis, unspecified
0.000 0.973 0.027
E22.1 Hyperprolactinaemia
0.000 0.973 0.027

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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