TreeWAS – Variant ID: rs2143178

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50 Crohn's disease [regional enteritis]	0.000	0.000	1.000
K50.9 Crohn's disease, unspecified	0.000	0.000	1.000
K51 Ulcerative colitis	0.000	0.001	0.999
K50-K52 Noninfective enteritis and colitis	0.000	0.002	0.998
K51.9 Ulcerative colitis, unspecified	0.000	0.004	0.996
K70 Alcoholic liver disease	0.984	0.016	0.000
K70.3 Alcoholic cirrhosis of liver	0.979	0.021	0.000
K50.1 Crohn's disease of large intestine	0.000	0.023	0.977
K70-K77 Diseases of liver	0.969	0.031	0.000
K70.9 Alcoholic liver disease, unspecified	0.952	0.048	0.000
K70.4 Alcoholic hepatic failure	0.952	0.048	0.000
K50.0 Crohn's disease of small intestine	0.000	0.053	0.947
K76 Other diseases of liver	0.943	0.057	0.000
K51.8 Other ulcerative colitis	0.000	0.061	0.939
K72 Hepatic failure, not elsewhere classified	0.937	0.063	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.068	0.932
K76.6 Portal hypertension	0.915	0.085	0.000
K51.5 Mucosal proctocolitis	0.000	0.087	0.913
K72.9 Hepatic failure, unspecified	0.882	0.118	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.156	0.844
K74 Fibrosis and cirrhosis of liver	0.841	0.159	0.000
K70.0 Alcoholic fatty liver	0.827	0.173	0.000
K74.6 Other and unspecified cirrhosis of liver	0.807	0.193	0.000
K72.0 Acute and subacute hepatic failure	0.792	0.208	0.000
K76.9 Liver disease, unspecified	0.786	0.214	0.000
K71 Toxic liver disease	0.744	0.256	0.000
K72.1 Chronic hepatic failure	0.740	0.260	0.000
K76.1 Chronic passive congestion of liver	0.739	0.261	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.264	0.736
K76.0 Fatty (change of) liver, not elsewhere classified	0.718	0.282	0.000
K70.1 Alcoholic hepatitis	0.718	0.282	0.000
K50.8 Other Crohn's disease	0.000	0.295	0.705
K77 Liver disorders in diseases classified elsewhere	0.695	0.305	0.000
K73 Chronic hepatitis, not elsewhere classified	0.692	0.308	0.000
K74.5 Biliary cirrhosis, unspecified	0.681	0.319	0.000
K76.5 Hepatic veno-occlusive disease	0.676	0.324	0.000
K76.4 Peliosis hepatis	0.676	0.324	0.000
K76.3 Infarction of liver	0.676	0.324	0.000
K76.2 Central haemorrhagic necrosis of liver	0.676	0.324	0.000
K76.7 Hepatorenal syndrome	0.675	0.324	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.656	0.343	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.396	0.604
K74.4 Secondary biliary cirrhosis	0.603	0.397	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.603	0.397	0.000
K74.1 Hepatic sclerosis	0.603	0.397	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.583	0.417	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.576	0.424	0.000
K71.9 Toxic liver disease, unspecified	0.534	0.466	0.000
K71.8 Toxic liver disease with other disorders of liver	0.534	0.466	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.534	0.466	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.534	0.466	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.534	0.466	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.534	0.466	0.000
K71.2 Toxic liver disease with acute hepatitis	0.534	0.466	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.534	0.466	0.000
K71.0 Toxic liver disease with cholestasis	0.534	0.466	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.498	0.502	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.498	0.502	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.496	0.504	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.496	0.504	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.496	0.504	0.000
K76.8 Other specified diseases of liver	0.482	0.518	0.000
K74.3 Primary biliary cirrhosis	0.427	0.573	0.000
K51.4 Pseudopolyposis of colon	0.001	0.636	0.363
K73.9 Chronic hepatitis, unspecified	0.355	0.644	0.000
K74.0 Hepatic fibrosis	0.302	0.697	0.001
K75 Other inflammatory liver diseases	0.240	0.760	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.177	0.823	0.000
K75.2 Nonspecific reactive hepatitis	0.172	0.827	0.000
K75.1 Phlebitis of portal vein	0.172	0.827	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.160	0.840	0.000
I83 Varicose veins of lower extremities	0.156	0.844	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.848	0.152
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.146	0.854	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.145	0.854	0.000
I85 Oesophageal varices	0.145	0.855	0.000
K75.0 Abscess of liver	0.145	0.855	0.000
I85.9 Oesophageal varices without bleeding	0.145	0.855	0.000
I86 Varicose veins of other sites	0.142	0.858	0.000
I82 Other venous embolism and thrombosis	0.137	0.863	0.000
K75.8 Other specified inflammatory liver diseases	0.133	0.867	0.000
K75.9 Inflammatory liver disease, unspecified	0.132	0.868	0.000
I86.4 Gastric varices	0.130	0.870	0.000
I81 Portal vein thrombosis	0.125	0.875	0.000
I82.8 Embolism and thrombosis of other specified veins	0.125	0.875	0.000
I86.1 Scrotal varices	0.119	0.881	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.119	0.881	0.000
K52.3 Indeterminate colitis	0.000	0.882	0.118
I86.8 Varicose veins of other specified sites	0.116	0.884	0.000
I85.0 Oesophageal varices with bleeding	0.111	0.889	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.891	0.109
I86.2 Pelvic varices	0.105	0.895	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.103	0.897	0.000
I86.3 Vulval varices	0.102	0.898	0.000
I86.0 Sublingual varices	0.102	0.898	0.000
I88 Nonspecific lymphadenitis	0.100	0.899	0.000
I82.3 Embolism and thrombosis of renal vein	0.098	0.901	0.000
I82.1 Thrombophlebitis migrans	0.098	0.901	0.000
I82.0 Budd-Chiari syndrome	0.098	0.901	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.097	0.903	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.903	0.096
I82.2 Embolism and thrombosis of vena cava	0.093	0.907	0.000
I87 Other disorders of veins	0.084	0.916	0.000
K75.4 Autoimmune hepatitis	0.082	0.918	0.001
K52.1 Toxic gastro-enteritis and colitis	0.000	0.924	0.076
I88.8 Other nonspecific lymphadenitis	0.072	0.928	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.072	0.928	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.072	0.928	0.000
I87.1 Compression of vein	0.071	0.929	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.068	0.932	0.000
I87.9 Disorder of vein, unspecified	0.060	0.940	0.000
I87.0 Postphlebitic syndrome	0.060	0.940	0.000
I80 Phlebitis and thrombophlebitis	0.049	0.951	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.956	0.044
I87.8 Other specified disorders of veins	0.043	0.956	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.038	0.962	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.037	0.963	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.035	0.965	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.034	0.965	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.034	0.966	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.033	0.967	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.028	0.972	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.026	0.974	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.023	0.977	0.000
I89.1 Lymphangitis	0.022	0.977	0.000
T42.4 Benzodiazepines	0.022	0.978	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.022	0.978	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.021	0.979	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.019	0.981	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.000	0.981	0.019
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.018	0.981	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.018	0.982	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.018	0.982	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.018	0.982	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.018	0.982	0.000
T38.9 Other and unspecified hormone antagonists	0.017	0.983	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.017	0.983	0.000
T38.7 Androgens and anabolic congeners	0.017	0.983	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.017	0.983	0.000
T38.5 Other oestrogens and progestogens	0.017	0.983	0.000
T38.4 Oral contraceptives	0.017	0.983	0.000
T38.2 Antithyroid drugs	0.017	0.983	0.000
T38.1 Thyroid hormones and substitutes	0.017	0.983	0.000
T38.0 Glucocorticoids and synthetic analogues	0.017	0.983	0.000
T36 Poisoning by systemic antibiotics	0.017	0.983	0.000
S91.3 Open wound of other parts of foot	0.017	0.983	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.016	0.984	0.000
S91 Open wound of ankle and foot	0.016	0.984	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.016	0.984	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.016	0.984	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.016	0.984	0.000
T42.0 Hydantoin derivatives	0.016	0.984	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.016	0.984	0.000
I89.0 Lymphoedema, not elsewhere classified	0.016	0.984	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.016	0.984	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.984	0.016
T50.9 Other and unspecified drugs, medicaments and biological substances	0.015	0.984	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.015	0.985	0.000
S91.1 Open wound of toe(s) without damage to nail	0.015	0.985	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.015	0.985	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.015	0.985	0.000
T42.3 Barbiturates	0.015	0.985	0.000
T42.2 Succinimides and oxazolidinediones	0.015	0.985	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.015	0.985	0.000
T45.0 Antiallergic and antiemetic drugs	0.015	0.985	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.014	0.986	0.000
S90-S99 Injuries to the ankle and foot	0.014	0.986	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.014	0.986	0.000
T42.1 Iminostilbenes	0.014	0.986	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.014	0.986	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.014	0.986	0.000
T46.7 Peripheral vasodilators	0.014	0.986	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.014	0.986	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.014	0.986	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.986	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.014	0.986	0.000
T50.8 Diagnostic agents	0.013	0.987	0.000
T50.7 Analeptics and opioid receptor antagonists	0.013	0.987	0.000
T50.5 Appetite depressants	0.013	0.987	0.000
T50.4 Drugs affecting uric acid metabolism	0.013	0.987	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.013	0.987	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.013	0.987	0.000
T50.1 Loop [high-ceiling] diuretics	0.013	0.987	0.000
T50.0 Mineralocorticoids and their antagonists	0.013	0.987	0.000
T36.0 Penicillins	0.013	0.987	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.013	0.987	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.013	0.987	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.013	0.987	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.013	0.987	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.013	0.987	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.013	0.987	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.013	0.987	0.000
T44.0 Anticholinesterase agents	0.013	0.987	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.013	0.987	0.000
T45.8 Other primarily systemic and haematological agents	0.013	0.987	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.013	0.987	0.000
T45.6 Fibrinolysis-affecting drugs	0.013	0.987	0.000
T45.4 Iron and its compounds	0.013	0.987	0.000
T45.3 Enzymes, not elsewhere classified	0.013	0.987	0.000
T45.2 Vitamins, not elsewhere classified	0.013	0.987	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
S90 Superficial injury of ankle and foot	0.013	0.987	0.000
T45.5 Anticoagulants	0.012	0.987	0.000
T46.1 Calcium-channel blockers	0.012	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.012	0.988	0.000
T36.8 Other systemic antibiotics	0.012	0.988	0.000
T36.7 Antifungal antibiotics, systemically used	0.012	0.988	0.000
T36.6 Rifamycins	0.012	0.988	0.000
T36.5 Aminoglycosides	0.012	0.988	0.000
T36.4 Tetracyclines	0.012	0.988	0.000
T36.3 Macrolides	0.012	0.988	0.000
T36.2 Chloramphenicol group	0.012	0.988	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.012	0.988	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.012	0.988	0.000
S99 Other and unspecified injuries of ankle and foot	0.012	0.988	0.000
S91.7 Multiple open wounds of ankle and foot	0.012	0.988	0.000
S91.2 Open wound of toe(s) with damage to nail	0.012	0.988	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.012	0.988	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.012	0.988	0.000
T37.5 Antiviral drugs	0.012	0.988	0.000
T37.4 Anthelminthics	0.012	0.988	0.000
T37.3 Other antiprotozoal drugs	0.012	0.988	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.012	0.988	0.000
T37.1 Antimycobacterial drugs	0.012	0.988	0.000
T37.0 Sulphonamides	0.012	0.988	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.012	0.988	0.000
S91.0 Open wound of ankle	0.012	0.988	0.000
T43.6 Psychostimulants with abuse potential	0.012	0.988	0.000
T41.5 Therapeutic gases	0.011	0.988	0.000
T41.4 Anaesthetic, unspecified	0.011	0.988	0.000
T41.3 Local anaesthetics	0.011	0.988	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.988	0.000
T41.1 Intravenous anaesthetics	0.011	0.988	0.000
T41.0 Inhaled anaesthetics	0.011	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.988	0.000
T48.5 Anti-common-cold drugs	0.011	0.988	0.000
T48.4 Expectorants	0.011	0.988	0.000
T48.3 Antitussives	0.011	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.988	0.000
T48.0 Oxytocic drugs	0.011	0.988	0.000
T49.9 Topical agent, unspecified	0.011	0.988	0.000
T49.8 Other topical agents	0.011	0.988	0.000
T49.7 Dental drugs, topically applied	0.011	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.988	0.000
T49.2 Local astringents and local detergents	0.011	0.988	0.000
T49.1 Antipruritics	0.011	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.988	0.000
O03.9 Complete or unspecified, without complication	0.011	0.989	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.011	0.989	0.000
S90.8 Other superficial injuries of ankle and foot	0.011	0.989	0.000
S97 Crushing injury of ankle and foot	0.011	0.989	0.000
S99.8 Other specified injuries of ankle and foot	0.011	0.989	0.000
S98 Traumatic amputation of ankle and foot	0.011	0.989	0.000
S95 Injury of blood vessels at ankle and foot level	0.011	0.989	0.000
S94 Injury of nerves at ankle and foot level	0.011	0.989	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.010	0.990	0.000
S90.3 Contusion of other and unspecified parts of foot	0.010	0.990	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.010	0.990	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.010	0.990	0.000
T47.7 Emetics	0.010	0.990	0.000
T47.6 Antidiarrhoeal drugs	0.010	0.990	0.000
T47.5 Digestants	0.010	0.990	0.000
T47.4 Other laxatives	0.010	0.990	0.000
T47.3 Saline and osmotic laxatives	0.010	0.990	0.000
T47.2 Stimulant laxatives	0.010	0.990	0.000
T47.0 Histamine H(2)-receptor antagonists	0.010	0.990	0.000
T39.0 Salicylates	0.010	0.990	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.010	0.990	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.010	0.990	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.009	0.990	0.000
T66-T78 Other and unspecified effects of external causes	0.010	0.990	0.000
E23.2 Diabetes insipidus	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.009	0.991	0.000
S90.2 Contusion of toe(s) with damage to nail	0.009	0.991	0.000
S90.1 Contusion of toe(s) without damage to nail	0.009	0.991	0.000
S92 Fracture of foot, except ankle	0.009	0.991	0.000
T21 Burn and corrosion of trunk	0.009	0.991	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.009	0.991	0.000
T43.2 Other and unspecified antidepressants	0.009	0.991	0.000
S93.1 Dislocation of toe(s)	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
H20.9 Iridocyclitis, unspecified	0.009	0.991	0.000
S99.7 Multiple injuries of ankle and foot	0.009	0.991	0.000
S90.0 Contusion of ankle	0.009	0.991	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.009	0.991	0.000
T39.4 Antirheumatics, not elsewhere classified	0.009	0.991	0.000
T39.2 Pyrazolone derivatives	0.009	0.991	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.009	0.991	0.000
E22.1 Hyperprolactinaemia	0.009	0.991	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.009	0.991	0.000
T66 Unspecified effects of radiation	0.009	0.991	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.009	0.991	0.000
S93.0 Dislocation of ankle joint	0.008	0.991	0.000
T23 Burn and corrosion of wrist and hand	0.008	0.991	0.000
T21.2 Burn of second degree of trunk	0.008	0.992	0.000
E34 Other endocrine disorders	0.008	0.992	0.000
E34.9 Endocrine disorder, unspecified	0.008	0.992	0.000
S93.4 Sprain and strain of ankle	0.008	0.992	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.008	0.992	0.000
S93.5 Sprain and strain of toe(s)	0.008	0.992	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.008	0.992	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.008	0.992	0.000
E20-E35 Disorders of other endocrine glands	0.008	0.992	0.000
T93 Sequelae of injuries of lower limb	0.008	0.992	0.000
E22.0 Acromegaly and pituitary gigantism	0.008	0.992	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.008	0.992	0.000
S97.1 Crushing injury of toe(s)	0.008	0.992	0.000
S97.0 Crushing injury of ankle	0.008	0.992	0.000
S40-S49 Injuries to the shoulder and upper arm	0.008	0.992	0.000
T68 Hypothermia	0.008	0.992	0.000
S99.9 Unspecified injury of ankle and foot	0.008	0.992	0.000
I49.3 Ventricular premature depolarisation	0.008	0.992	0.000
S40 Superficial injury of shoulder and upper arm	0.008	0.992	0.000
T20 Burn and corrosion of head and neck	0.008	0.992	0.000
E23.0 Hypopituitarism	0.008	0.992	0.000
S70-S79 Injuries to the hip and thigh	0.008	0.992	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.008	0.992	0.000
S94.8 Injury of other nerves at ankle and foot level	0.008	0.992	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.008	0.992	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.008	0.992	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.008	0.992	0.000
S94.1 Injury of medial plantar nerve	0.008	0.992	0.000
S94.0 Injury of lateral plantar nerve	0.008	0.992	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.008	0.992	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.008	0.992	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.008	0.992	0.000
S95.2 Injury of dorsal vein of foot	0.008	0.992	0.000
S95.1 Injury of plantar artery of foot	0.008	0.992	0.000
S95.0 Injury of dorsal artery of foot	0.008	0.992	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.008	0.992	0.000
S98.3 Traumatic amputation of other parts of foot	0.008	0.992	0.000
S98.2 Traumatic amputation of two or more toes	0.008	0.992	0.000
S98.1 Traumatic amputation of one toe	0.008	0.992	0.000
S98.0 Traumatic amputation of foot at ankle level	0.008	0.992	0.000
T25 Burn and corrosion of ankle and foot	0.008	0.992	0.000
S92.4 Fracture of great toe	0.008	0.992	0.000
T70 Effects of air pressure and water pressure	0.008	0.992	0.000
T18 Foreign body in alimentary tract	0.008	0.992	0.000
R68.8 Other specified general symptoms and signs	0.008	0.992	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.007	0.992	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.007	0.992	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.007	0.992	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.007	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
S72 Fracture of femur	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.008	0.992	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.008	0.992	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.007	0.992	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.007	0.992	0.000
T21.0 Burn of unspecified degree of trunk	0.007	0.992	0.000
E29 Testicular dysfunction	0.007	0.992	0.000
T75 Effects of other external causes	0.007	0.992	0.000
S92.1 Fracture of talus	0.007	0.993	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.007	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
S40.0 Contusion of shoulder and upper arm	0.007	0.993	0.000
T19 Foreign body in genito-urinary tract	0.007	0.993	0.000
T20.0 Burn of unspecified degree of head and neck	0.007	0.993	0.000
T23.2 Burn of second degree of wrist and hand	0.007	0.993	0.000
T00-T07 Injuries involving multiple body regions	0.007	0.993	0.000
T18.1 Foreign body in oesophagus	0.007	0.993	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.007	0.993	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
I98.0 Cardiovascular syphilis	0.007	0.993	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T33-T35 Frostbite	0.007	0.993	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.007	0.993	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.007	0.993	0.000
T74 Maltreatment syndromes	0.007	0.993	0.000
T73 Effects of other deprivation	0.007	0.993	0.000
T69 Other effects of reduced temperature	0.007	0.993	0.000
T67 Effects of heat and light	0.007	0.993	0.000
T71 Asphyxiation	0.007	0.993	0.000
E34.0 Carcinoid syndrome	0.007	0.993	0.000
S92.7 Multiple fractures of foot	0.007	0.993	0.000
T93.1 Sequelae of fracture of femur	0.007	0.993	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.007	0.993	0.000
E22.8 Other hyperfunction of pituitary gland	0.007	0.993	0.000
T93.2 Sequelae of other fractures of lower limb	0.007	0.993	0.000
S92.9 Fracture of foot, unspecified	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.007	0.993	0.000
T21.7 Corrosion of third degree of trunk	0.007	0.993	0.000
T21.6 Corrosion of second degree of trunk	0.007	0.993	0.000
T21.5 Corrosion of first degree of trunk	0.007	0.993	0.000
T21.4 Corrosion of unspecified degree of trunk	0.007	0.993	0.000
T21.3 Burn of third degree of trunk	0.007	0.993	0.000
T21.1 Burn of first degree of trunk	0.007	0.993	0.000
T98 Sequelae of other and unspecified effects of external causes	0.007	0.993	0.000
T93.0 Sequelae of open wound of lower limb	0.007	0.993	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.007	0.993	0.000
H20 Iridocyclitis	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
S72.9 Fracture of femur, part unspecified	0.007	0.993	0.000
S92.2 Fracture of other tarsal bone(s)	0.007	0.993	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.007	0.993	0.000
S92.40 Fracture of great toe (closed)	0.007	0.993	0.000
E24.2 Drug-induced Cushing's syndrome	0.007	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.007	0.993	0.000
T40.8 Lysergide [LSD]	0.007	0.993	0.000
T40.7 Cannabis (derivatives)	0.007	0.993	0.000
T40.5 Cocaine	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
T40.1 Heroin	0.007	0.993	0.000
T40.0 Opium	0.007	0.993	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
S92.5 Fracture of other toe	0.007	0.993	0.000
T23.1 Burn of first degree of wrist and hand	0.007	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.007	0.993	0.000
S72.4 Fracture of lower end of femur	0.007	0.993	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.007	0.993	0.000
S72.3 Fracture of shaft of femur	0.007	0.993	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.006	0.993	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.006	0.993	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.006	0.993	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.006	0.993	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.006	0.993	0.000
S20-S29 Injuries to the thorax	0.007	0.993	0.000
T70.3 Caisson disease [decompression sickness]	0.006	0.993	0.000
S72.2 Subtrochanteric fracture	0.006	0.993	0.000
T15 Foreign body on external eye	0.006	0.993	0.000
T17 Foreign body in respiratory tract	0.006	0.993	0.000
T39.1 4-Aminophenol derivatives	0.007	0.993	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
E20 Hypoparathyroidism	0.006	0.994	0.000
H20.0 Acute and subacute iridocyclitis	0.006	0.994	0.000
T23.3 Burn of third degree of wrist and hand	0.006	0.994	0.000
T23.7 Corrosion of third degree of wrist and hand	0.006	0.994	0.000
T23.6 Corrosion of second degree of wrist and hand	0.006	0.994	0.000
T23.5 Corrosion of first degree of wrist and hand	0.006	0.994	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.006	0.994	0.000
T18.5 Foreign body in anus and rectum	0.006	0.994	0.000
E34.5 Androgen resistance syndrome	0.006	0.994	0.000
E34.4 Constitutional tall stature	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.006	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.006	0.994	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.006	0.994	0.000
S93.40 Sprain of unspecified ligament of ankle	0.006	0.994	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E32 Diseases of thymus	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.006	0.994	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.994	0.000
E25 Adrenogenital disorders	0.006	0.994	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.006	0.994	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.006	0.994	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.006	0.994	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.994	0.000
T25.2 Burn of second degree of ankle and foot	0.006	0.994	0.000
S21 Open wound of thorax	0.006	0.994	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.006	0.994	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.006	0.994	0.000
S48 Traumatic amputation of shoulder and upper arm	0.006	0.994	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.006	0.994	0.000
S44 Injury of nerves at shoulder and upper arm level	0.006	0.994	0.000
S47 Crushing injury of shoulder and upper arm	0.006	0.994	0.000
T95 Sequelae of burns, corrosions and frostbite	0.006	0.994	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.006	0.994	0.000
T91 Sequelae of injuries of neck and trunk	0.006	0.994	0.000
S92.10 Fracture of talus (closed)	0.006	0.994	0.000
T16 Foreign body in ear	0.006	0.994	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.006	0.994	0.000
S72.8 Fractures of other parts of femur	0.006	0.994	0.000
T20.7 Corrosion of third degree of head and neck	0.006	0.994	0.000
T20.6 Corrosion of second degree of head and neck	0.006	0.994	0.000
T20.5 Corrosion of first degree of head and neck	0.006	0.994	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.006	0.994	0.000
T20.3 Burn of third degree of head and neck	0.006	0.994	0.000
T31 Burns classified according to extent of body surface involved	0.006	0.994	0.000
S43.1 Dislocation of acromioclavicular joint	0.006	0.994	0.000
E34.8 Other specified endocrine disorders	0.006	0.994	0.000
T19.1 Foreign body in bladder	0.006	0.994	0.000
T75.4 Effects of electric current	0.006	0.994	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.006	0.994	0.000
E23.7 Disorder of pituitary gland, unspecified	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations