TreeWAS – Variant ID: rs2185077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44.5 Skin of trunk	0.245	0.755	0.000
C44 Other malignant neoplasms of skin	0.019	0.981	0.000
C44.4 Skin of scalp and neck	0.018	0.982	0.000
C44.6 Skin of upper limb, including shoulder	0.016	0.984	0.000
C44.8 Overlapping lesion of skin	0.014	0.986	0.000
C44.0 Skin of lip	0.014	0.986	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.014	0.986	0.000
C44.2 Skin of ear and external auricular canal	0.011	0.989	0.000
D50.9 Iron deficiency anaemia, unspecified	0.009	0.991	0.000
Z86.7 Personal history of diseases of the circulatory system	0.000	0.992	0.008
M10.99 Gout, unspecified (Site unspecified)	0.000	0.993	0.007
Z95.2 Presence of prosthetic heart valve	0.000	0.993	0.007
K76.0 Fatty (change of) liver, not elsewhere classified	0.007	0.993	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.007	0.993	0.000
J98.4 Other disorders of lung	0.000	0.994	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.006	0.994	0.000
S43.0 Dislocation of shoulder joint	0.000	0.995	0.005
J38.4 Oedema of larynx	0.000	0.995	0.005
Z95.4 Presence of other heart-valve replacement	0.000	0.995	0.005
J38.1 Polyp of vocal cord and larynx	0.000	0.995	0.005
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.995	0.005
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.995	0.005
D50 Iron deficiency anaemia	0.005	0.995	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.005	0.995	0.000
J38.7 Other diseases of larynx	0.000	0.995	0.005
H93.1 Tinnitus	0.000	0.995	0.005
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
J38.3 Other diseases of vocal cords	0.000	0.996	0.004
K14.8 Other diseases of tongue	0.000	0.996	0.004
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.996	0.004
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.996	0.004
S42.10 Fracture of scapula (closed)	0.000	0.996	0.004
C44.1 Skin of eyelid, including canthus	0.004	0.996	0.000
J38.2 Nodules of vocal cords	0.000	0.996	0.004
A46 Erysipelas	0.000	0.996	0.004
C43-C44 Melanoma and other malignant neoplasms of skin	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.000	0.996	0.004
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.996	0.004
C91.1 Chronic lymphocytic leukaemia	0.000	0.996	0.004
J38.5 Laryngeal spasm	0.000	0.996	0.004
D50.1 Sideropenic dysphagia	0.004	0.996	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.996	0.004
J38.6 Stenosis of larynx	0.000	0.996	0.004
S42.1 Fracture of scapula	0.000	0.996	0.004
Z95.3 Presence of xenogenic heart valve	0.000	0.997	0.003
S43.4 Sprain and strain of shoulder joint	0.000	0.997	0.003
S43.1 Dislocation of acromioclavicular joint	0.000	0.997	0.003
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.003	0.997	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.997	0.003
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.997	0.003
M65.9 Synovitis and tenosynovitis, unspecified	0.003	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.000	0.997	0.003
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.997	0.003
S42 Fracture of shoulder and upper arm	0.000	0.997	0.003
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.997	0.003
S43.2 Dislocation of sternoclavicular joint	0.000	0.997	0.003
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.003	0.997	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.997	0.003
T81.4 Infection following a procedure, not elsewhere classified	0.000	0.997	0.003
S42.11 Fracture of scapula (open)	0.000	0.997	0.003
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.997	0.003
A40 Streptococcal septicaemia	0.000	0.997	0.003
S42.0 Fracture of clavicle	0.000	0.997	0.003
D50-D53 Nutritional anaemias	0.003	0.997	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.003	0.997	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.003	0.997	0.000
C91 Lymphoid leukaemia	0.000	0.997	0.003
S41 Open wound of shoulder and upper arm	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.000	0.997	0.003
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.997	0.003
S45 Injury of blood vessels at shoulder and upper arm level	0.000	0.997	0.003
S44 Injury of nerves at shoulder and upper arm level	0.000	0.997	0.003
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.003	0.997	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.002	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.997	0.003
S48 Traumatic amputation of shoulder and upper arm	0.000	0.997	0.002
S47 Crushing injury of shoulder and upper arm	0.000	0.997	0.002
A40.1 Septicaemia due to streptococcus, group B	0.000	0.997	0.003
C91.4 Hairy-cell leukaemia	0.000	0.997	0.003
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.002	0.997	0.000
A40.8 Other streptococcal septicaemia	0.000	0.997	0.003
C91.5 Adult T-cell leukaemia	0.000	0.997	0.002
S40.0 Contusion of shoulder and upper arm	0.000	0.997	0.002
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.997	0.002
D52 Folate deficiency anaemia	0.002	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
Z95.1 Presence of aortocoronary bypass graft	0.000	0.997	0.003
A40.0 Septicaemia due to streptococcus, group A	0.000	0.997	0.002
S42.2 Fracture of upper end of humerus	0.000	0.997	0.002
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.998	0.002
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
A40.2 Septicaemia due to streptococcus, group D	0.000	0.998	0.002
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.000	0.998	0.002
S46.3 Injury of muscle and tendon of triceps	0.000	0.998	0.002
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.998	0.002
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.998	0.002
A40.9 Streptococcal septicaemia, unspecified	0.000	0.998	0.002
C44.7 Skin of lower limb, including hip	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.998	0.002
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
A40.3 Septicaemia due to Streptococcus pneumoniae	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
S42.21 Fracture of upper end of humerus (open)	0.000	0.998	0.002
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.998	0.002
C91.7 Other lymphoid leukaemia	0.000	0.998	0.002
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.998	0.002
C91.3 Prolymphocytic leukaemia	0.000	0.998	0.002
C91.2 Subacute lymphocytic leukaemia	0.000	0.998	0.002
S41.7 Multiple open wounds of shoulder and upper arm	0.000	0.998	0.002
S41.0 Open wound of shoulder	0.000	0.998	0.002
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.998	0.002
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.000	0.998	0.002
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.998	0.002
C91.0 Acute lymphoblastic leukaemia	0.000	0.998	0.002
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.998	0.002
S44.2 Injury of radial nerve at upper arm level	0.000	0.998	0.002
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.998	0.002
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.000	0.998	0.002
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.000	0.998	0.002
S45.3 Injury of superficial vein at shoulder and upper arm level	0.000	0.998	0.002
S45.2 Injury of axillary or brachial vein	0.000	0.998	0.002
S45.1 Injury of brachial artery	0.000	0.998	0.002
S45.0 Injury of axillary artery	0.000	0.998	0.002
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.998	0.002
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.000	0.998	0.002
S44.8 Injury of other nerves at shoulder and upper arm level	0.000	0.998	0.002
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.000	0.998	0.002
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.000	0.998	0.002
S44.4 Injury of musculocutaneous nerve	0.000	0.998	0.002
S44.3 Injury of axillary nerve	0.000	0.998	0.002
S44.1 Injury of median nerve at upper arm level	0.000	0.998	0.002
S44.0 Injury of ulnar nerve at upper arm level	0.000	0.998	0.002
A30-A49 Other bacterial diseases	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.000	0.998	0.002
S48.1 Traumatic amputation at level between shoulder and elbow	0.000	0.998	0.002
S48.0 Traumatic amputation at shoulder joint	0.000	0.998	0.002
D53 Other nutritional anaemias	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.000	0.998	0.002
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.000	0.998	0.002
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.998	0.002
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.998	0.002
A31.9 Mycobacterial infection, unspecified	0.000	0.998	0.002
D37.7 Other digestive organs	0.000	0.998	0.002
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000
A31 Infection due to other mycobacteria	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.998	0.002
S42.3 Fracture of shaft of humerus	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.998	0.002
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.000	0.998	0.002
G30 Alzheimer's disease	0.002	0.998	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
D51.2 Transcobalamin II deficiency	0.002	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.002	0.998	0.000
N80.1 Endometriosis of ovary	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
A48 Other bacterial diseases, not elsewhere classified	0.000	0.998	0.002
A44 Bartonellosis	0.000	0.998	0.002
A43 Nocardiosis	0.000	0.998	0.002
A37 Whooping cough	0.000	0.998	0.002
A36 Diphtheria	0.000	0.998	0.002
A32 Listeriosis	0.000	0.998	0.002
A30 Leprosy [Hansen's disease]	0.000	0.998	0.002
A38 Scarlet fever	0.000	0.998	0.002
A35 Other tetanus	0.000	0.998	0.002
A34 Obstetrical tetanus	0.000	0.998	0.002
A33 Tetanus neonatorum	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
A31.8 Other mycobacterial infections	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
A31.1 Cutaneous mycobacterial infection	0.000	0.998	0.002
M10.9 Gout, unspecified	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
Z41 Procedures for purposes other than remedying health state	0.000	0.998	0.002
H93.0 Degenerative and vascular disorders of ear	0.000	0.998	0.002
K70.1 Alcoholic hepatitis	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.001	0.998	0.001
A42 Actinomycosis	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.998	0.001
A31.0 Pulmonary mycobacterial infection	0.000	0.998	0.002
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.001	0.998	0.000
S22.3 Fracture of rib	0.002	0.998	0.000
D24 Benign neoplasm of breast	0.002	0.998	0.000
K63.2 Fistula of intestine	0.000	0.998	0.002
G30-G32 Other degenerative diseases of the nervous system	0.002	0.998	0.000
A48.8 Other specified bacterial diseases	0.000	0.998	0.001
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.001
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
K14 Diseases of tongue	0.000	0.998	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
A30.9 Leprosy, unspecified	0.000	0.998	0.001
A30.8 Other forms of leprosy	0.000	0.998	0.001
A30.5 Lepromatous leprosy	0.000	0.998	0.001
A30.4 Borderline lepromatous leprosy	0.000	0.998	0.001
A30.3 Borderline leprosy	0.000	0.998	0.001
A30.2 Borderline tuberculoid leprosy	0.000	0.998	0.001
A30.1 Tuberculoid leprosy	0.000	0.998	0.001
A30.0 Indeterminate leprosy	0.000	0.998	0.001
A32.9 Listeriosis, unspecified	0.000	0.998	0.001
A32.8 Other forms of listeriosis	0.000	0.998	0.001
A32.7 Listerial septicaemia	0.000	0.998	0.001
A32.1 Listerial meningitis and meningoencephalitis	0.000	0.998	0.001
A32.0 Cutaneous listeriosis	0.000	0.998	0.001
A36.9 Diphtheria, unspecified	0.000	0.998	0.001
A36.8 Other diphtheria	0.000	0.998	0.001
A36.3 Cutaneous diphtheria	0.000	0.998	0.001
A36.2 Laryngeal diphtheria	0.000	0.998	0.001
A36.1 Nasopharyngeal diphtheria	0.000	0.998	0.001
A36.0 Pharyngeal diphtheria	0.000	0.998	0.001
A37.9 Whooping cough, unspecified	0.000	0.998	0.001
A37.8 Whooping cough due to other Bordetella species	0.000	0.998	0.001
A37.1 Whooping cough due to Bordetella parapertussis	0.000	0.998	0.001
A37.0 Whooping cough due to Bordetella pertussis	0.000	0.998	0.001
A43.9 Nocardiosis, unspecified	0.000	0.998	0.001
A43.8 Other forms of nocardiosis	0.000	0.998	0.001
A43.1 Cutaneous nocardiosis	0.000	0.998	0.001
A43.0 Pulmonary nocardiosis	0.000	0.998	0.001
A44.9 Bartonellosis, unspecified	0.000	0.998	0.001
A44.8 Other forms of bartonellosis	0.000	0.998	0.001
A44.1 Cutaneous and mucocutaneous bartonellosis	0.000	0.998	0.001
A44.0 Systemic bartonellosis	0.000	0.998	0.001
A48.4 Brazilian purpuric fever	0.000	0.998	0.001
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.000	0.998	0.001
A48.0 Gas gangrene	0.000	0.998	0.001
G30.8 Other Alzheimer's disease	0.001	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.001
A48.3 Toxic shock syndrome	0.000	0.998	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.998	0.000
A39 Meningococcal infection	0.000	0.998	0.001
M10.98 Gout, unspecified (Other)	0.000	0.998	0.001
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M10.91 Gout, unspecified (Shoulder region)	0.000	0.998	0.001
H93.8 Other specified disorders of ear	0.000	0.998	0.001
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.001	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.001	0.998	0.001
A42.7 Actinomycotic septicaemia	0.000	0.998	0.001
A42.2 Cervicofacial actinomycosis	0.000	0.998	0.001
A42.1 Abdominal actinomycosis	0.000	0.998	0.001
A42.0 Pulmonary actinomycosis	0.000	0.998	0.001
H50.2 Vertical strabismus	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.001	0.998	0.000
H93.9 Disorder of ear, unspecified	0.000	0.998	0.001
Q24.3 Pulmonary infundibular stenosis	0.001	0.998	0.000
Q24.2 Cor triatriatum	0.001	0.998	0.000
Q24.1 Levocardia	0.001	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.998	0.000
Z41.3 Ear piercing	0.000	0.998	0.001
Z41.0 Hair transplant	0.000	0.998	0.001
M10.90 Gout, unspecified (Multiple sites)	0.000	0.998	0.001
Q25.4 Other congenital malformations of aorta	0.001	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.998	0.000
A42.9 Actinomycosis, unspecified	0.000	0.998	0.001
A48.1 Legionnaires' disease	0.000	0.998	0.001
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.001	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.001
Z41.2 Routine and ritual circumcision	0.000	0.998	0.001
M54.36 Sciatica (Lumbar region)	0.001	0.998	0.000
S22.31 Fracture of rib (open)	0.001	0.998	0.000
A42.8 Other forms of actinomycosis	0.000	0.998	0.001
C71.9 Brain, unspecified	0.001	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.001	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.001	0.998	0.000
Q26 Congenital malformations of great veins	0.001	0.998	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.001	0.999	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.999	0.001
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.001	0.999	0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.000	0.999	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
H05.2 Exophthalmic conditions	0.000	0.999	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.999	0.000
K14.3 Hypertrophy of tongue papillae	0.000	0.999	0.001
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.999	0.001
K14.2 Median rhomboid glossitis	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
Q24.6 Congenital heart block	0.001	0.999	0.000
Q21 Congenital malformations of cardiac septa	0.001	0.999	0.000
K14.5 Plicated tongue	0.000	0.999	0.001
K14.4 Atrophy of tongue papillae	0.000	0.999	0.001
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.999	0.001
K70.0 Alcoholic fatty liver	0.000	0.999	0.001
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.000	0.999	0.001
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.999	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.999	0.001
M10.92 Gout, unspecified (Upper arm)	0.000	0.999	0.001
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.999	0.001
H74.0 Tympanosclerosis	0.001	0.999	0.000
K01.0 Embedded teeth	0.000	0.999	0.001
M07.3 Other psoriatic arthropathies	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.999	0.001
A39.9 Meningococcal infection, unspecified	0.000	0.999	0.001
A39.8 Other meningococcal infections	0.000	0.999	0.001
A39.5 Meningococcal heart disease	0.000	0.999	0.001
A39.3 Chronic meningococcaemia	0.000	0.999	0.001
A39.2 Acute meningococcaemia	0.000	0.999	0.001
A39.1 Waterhouse-Friderichsen syndrome	0.000	0.999	0.001
G31.8 Other specified degenerative diseases of nervous system	0.001	0.999	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.999	0.001
M10.96 Gout, unspecified (Lower leg)	0.000	0.999	0.001
Q21.8 Other congenital malformations of cardiac septa	0.001	0.999	0.000
S22.1 Multiple fractures of thoracic spine	0.001	0.999	0.000
F33 Recurrent depressive disorder	0.001	0.999	0.000
K70 Alcoholic liver disease	0.000	0.999	0.001
D13.2 Duodenum	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001
K70.3 Alcoholic cirrhosis of liver	0.000	0.999	0.001
Q25.0 Patent ductus arteriosus	0.001	0.999	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.999	0.001
D68.2 Hereditary deficiency of other clotting factors	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.000	0.999	0.001
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
K14.6 Glossodynia	0.000	0.999	0.001
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.999	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.999	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.999	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.999	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.1 Persistent left superior vena cava	0.001	0.999	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.999	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.999	0.001
Q89 Other congenital malformations, not elsewhere classified	0.000	0.999	0.001
S22.50 Flail chest (closed)	0.001	0.999	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.001	0.999	0.000
K14.1 Geographic tongue	0.000	0.999	0.001
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.999	0.001
M07.38 Other psoriatic arthropathies (Other)	0.000	0.999	0.001
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.999	0.001
F33.4 Recurrent depressive disorder, currently in remission	0.001	0.999	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.999	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
Q27.4 Congenital phlebectasia	0.001	0.999	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.999	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.999	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.999	0.000
M10.94 Gout, unspecified (Hand)	0.000	0.999	0.001
A39.4 Meningococcaemia, unspecified	0.000	0.999	0.001
C04.9 Floor of mouth, unspecified	0.000	0.999	0.001
D37.9 Digestive organ, unspecified	0.000	0.999	0.001
F33.8 Other recurrent depressive disorders	0.001	0.999	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.001	0.999	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.001	0.999	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.999	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.999	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.999	0.000
Q20.4 Double inlet ventricle	0.001	0.999	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.999	0.000
Q20.2 Double outlet left ventricle	0.001	0.999	0.000
Q20.1 Double outlet right ventricle	0.001	0.999	0.000
Q20.0 Common arterial trunk	0.001	0.999	0.000
Q21.4 Aortopulmonary septal defect	0.001	0.999	0.000
Q21.2 Atrioventricular septal defect	0.001	0.999	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.999	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.999	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.999	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.999	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.999	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.999	0.000
Q22.1 Congenital pulmonary valve stenosis	0.001	0.999	0.000
Q22.0 Pulmonary valve atresia	0.001	0.999	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.999	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.999	0.001
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.999	0.001
O68 Labour and delivery complicated by foetal stress [distress]	0.001	0.999	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.999	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.999	0.001
A39.0 Meningococcal meningitis	0.000	0.999	0.001
H05.0 Acute inflammation of orbit	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.999	0.001
A49 Bacterial infection of unspecified site	0.000	0.999	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.999	0.001
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.999	0.001
S22.11 Multiple fractures of thoracic spine (open)	0.001	0.999	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.999	0.001
Q21.3 Tetralogy of Fallot	0.001	0.999	0.000
Q21.0 Ventricular septal defect	0.001	0.999	0.000
Q22.5 Ebstein's anomaly	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.000	0.999	0.001
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.999	0.001
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.999	0.001
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.999	0.001
Q85 Phakomatoses, not elsewhere classified	0.000	0.999	0.001
M54.37 Sciatica (Lumbosacral region)	0.001	0.999	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.999	0.001
H50.0 Convergent concomitant strabismus	0.000	0.999	0.001
K10.3 Alveolitis of jaws	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.000	0.999	0.001
S22.5 Flail chest	0.001	0.999	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.999	0.001
D37.5 Rectum	0.000	0.999	0.001
E21.2 Other hyperparathyroidism	0.001	0.999	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.999	0.001
K10.2 Inflammatory conditions of jaws	0.000	0.999	0.001
Q89.9 Congenital malformation, unspecified	0.000	0.999	0.001
Q89.8 Other specified congenital malformations	0.000	0.999	0.001
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.999	0.001
Q89.4 Conjoined twins	0.000	0.999	0.001
Q89.1 Congenital malformations of adrenal gland	0.000	0.999	0.001
H46 Optic neuritis	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.999	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.999	0.001
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.999	0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.999	0.000
Q21.1 Atrial septal defect	0.001	0.999	0.000
Q89.3 Situs inversus	0.000	0.999	0.001
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.999	0.001
F33.0 Recurrent depressive disorder, current episode mild	0.001	0.999	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.999	0.001
H53.1 Subjective visual disturbances	0.001	0.999	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.001	0.999	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.001	0.999	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations