TreeWAS – Variant ID: rs2187375

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C78.0 Secondary malignant neoplasm of lung	0.216	0.784	0.000
C79 Secondary malignant neoplasm of other sites	0.213	0.787	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.213	0.787	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.209	0.791	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.204	0.796	0.000
C77.1 Intrathoracic lymph nodes	0.203	0.797	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.200	0.800	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.199	0.801	0.000
C79.2 Secondary malignant neoplasm of skin	0.188	0.812	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.184	0.816	0.000
C79.6 Secondary malignant neoplasm of ovary	0.184	0.816	0.000
C80 Malignant neoplasm without specification of site	0.179	0.821	0.000
C78.7 Secondary malignant neoplasm of liver	0.172	0.828	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.167	0.833	0.000
C77.0 Lymph nodes of head, face and neck	0.167	0.833	0.000
C77.2 Intra-abdominal lymph nodes	0.165	0.835	0.000
C80.9 Malignant neoplasm, unspecified	0.164	0.836	0.000
C77.8 Lymph nodes of multiple regions	0.157	0.843	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.157	0.843	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.156	0.844	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.155	0.845	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.138	0.861	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.137	0.863	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.136	0.864	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.133	0.867	0.000
C77.4 Inguinal and lower limb lymph nodes	0.125	0.875	0.000
C76.3 Pelvis	0.121	0.879	0.000
C78.2 Secondary malignant neoplasm of pleura	0.114	0.886	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.111	0.888	0.000
C76.7 Other ill-defined sites	0.111	0.888	0.000
C76.5 Lower limb	0.111	0.888	0.000
C76.4 Upper limb	0.111	0.888	0.000
C76.1 Thorax	0.111	0.889	0.000
C76.0 Head, face and neck	0.111	0.889	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.104	0.896	0.000
C76.2 Abdomen	0.104	0.896	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.094	0.906	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.093	0.906	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.076	0.924	0.000
M10.99 Gout, unspecified (Site unspecified)	0.075	0.925	0.000
M10.9 Gout, unspecified	0.072	0.928	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.071	0.929	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.069	0.930	0.001
C77.5 Intrapelvic lymph nodes	0.066	0.934	0.000
M10.96 Gout, unspecified (Lower leg)	0.065	0.935	0.000
M10.94 Gout, unspecified (Hand)	0.052	0.948	0.000
M10.98 Gout, unspecified (Other)	0.051	0.948	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.051	0.948	0.000
M10.91 Gout, unspecified (Shoulder region)	0.051	0.948	0.000
C77.9 Lymph node, unspecified	0.051	0.949	0.000
M10.93 Gout, unspecified (Forearm)	0.051	0.949	0.000
M10.92 Gout, unspecified (Upper arm)	0.050	0.950	0.000
M10.90 Gout, unspecified (Multiple sites)	0.038	0.962	0.000
C77.3 Axillary and upper limb lymph nodes	0.033	0.967	0.000
M10 Gout	0.028	0.972	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.976	0.024
M10.3 Gout due to impairment of renal function	0.021	0.979	0.000
M10.4 Other secondary gout	0.020	0.980	0.000
M10.2 Drug-induced gout	0.020	0.980	0.000
M10.1 Lead-induced gout	0.020	0.980	0.000
S02.10 Fracture of base of skull (closed)	0.019	0.981	0.000
M10.0 Idiopathic gout	0.018	0.982	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.016	0.983	0.000
M10.38 Gout due to impairment of renal function (Other)	0.015	0.984	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.015	0.984	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.015	0.984	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.015	0.984	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.015	0.984	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.015	0.984	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.015	0.984	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.015	0.984	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.015	0.984	0.000
M10.19 Lead-induced gout (Site unspecified)	0.015	0.985	0.000
M10.18 Lead-induced gout (Other)	0.015	0.985	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.015	0.985	0.000
M10.16 Lead-induced gout (Lower leg)	0.015	0.985	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.015	0.985	0.000
M10.14 Lead-induced gout (Hand)	0.015	0.985	0.000
M10.13 Lead-induced gout (Forearm)	0.015	0.985	0.000
M10.12 Lead-induced gout (Upper arm)	0.015	0.985	0.000
M10.11 Lead-induced gout (Shoulder region)	0.015	0.985	0.000
M10.10 Lead-induced gout (Multiple sites)	0.015	0.985	0.000
M10.29 Drug-induced gout (Site unspecified)	0.015	0.985	0.000
M10.28 Drug-induced gout (Other)	0.015	0.985	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.015	0.985	0.000
M10.26 Drug-induced gout (Lower leg)	0.015	0.985	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.015	0.985	0.000
M10.24 Drug-induced gout (Hand)	0.015	0.985	0.000
M10.23 Drug-induced gout (Forearm)	0.015	0.985	0.000
M10.22 Drug-induced gout (Upper arm)	0.015	0.985	0.000
M10.21 Drug-induced gout (Shoulder region)	0.015	0.985	0.000
M10.20 Drug-induced gout (Multiple sites)	0.015	0.985	0.000
M10.49 Other secondary gout (Site unspecified)	0.015	0.985	0.000
M10.48 Other secondary gout (Other)	0.015	0.985	0.000
M10.47 Other secondary gout (Ankle and foot)	0.015	0.985	0.000
M10.46 Other secondary gout (Lower leg)	0.015	0.985	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.015	0.985	0.000
M10.44 Other secondary gout (Hand)	0.015	0.985	0.000
M10.43 Other secondary gout (Forearm)	0.015	0.985	0.000
M10.42 Other secondary gout (Upper arm)	0.015	0.985	0.000
M10.41 Other secondary gout (Shoulder region)	0.015	0.985	0.000
M10.40 Other secondary gout (Multiple sites)	0.015	0.985	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.013	0.987	0.000
M10.09 Idiopathic gout (Site unspecified)	0.013	0.987	0.000
M10.08 Idiopathic gout (Other)	0.013	0.987	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.013	0.987	0.000
M10.03 Idiopathic gout (Forearm)	0.013	0.987	0.000
M10.01 Idiopathic gout (Shoulder region)	0.013	0.987	0.000
M10.02 Idiopathic gout (Upper arm)	0.013	0.987	0.000
M10.06 Idiopathic gout (Lower leg)	0.012	0.987	0.000
M10.04 Idiopathic gout (Hand)	0.012	0.988	0.000
M10.00 Idiopathic gout (Multiple sites)	0.012	0.988	0.000
S02.1 Fracture of base of skull	0.009	0.991	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.993	0.007
C16.0 Cardia	0.006	0.994	0.000
C16 Malignant neoplasm of stomach	0.006	0.994	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.006	0.994	0.000
S02.11 Fracture of base of skull (open)	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.006	0.994	0.000
C16.2 Body of stomach	0.006	0.994	0.000
C16.9 Stomach, unspecified	0.006	0.994	0.000
C15 Malignant neoplasm of oesophagus	0.006	0.994	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.995	0.005
C16.5 Lesser curvature of stomach, unspecified	0.005	0.995	0.000
C15.9 Oesophagus, unspecified	0.005	0.995	0.000
C16.3 Pyloric antrum	0.005	0.995	0.000
C16.6 Greater curvature of stomach, unspecified	0.005	0.995	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.995	0.005
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.995	0.005
C15.4 Middle third of oesophagus	0.005	0.995	0.000
C16.4 Pylorus	0.005	0.995	0.000
C16.8 Overlapping lesion of stomach	0.005	0.995	0.000
H18.6 Keratoconus	0.000	0.996	0.004
C16.1 Fundus of stomach	0.004	0.996	0.000
C22.1 Intrahepatic bile duct carcinoma	0.004	0.996	0.000
C15.8 Overlapping lesion of oesophagus	0.004	0.996	0.000
C15.2 Abdominal part of oesophagus	0.004	0.996	0.000
C15.1 Thoracic part of oesophagus	0.004	0.996	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.004	0.996	0.000
C15-C26 Malignant neoplasms of digestive organs	0.004	0.996	0.000
S82.40 Fracture of fibula alone (closed)	0.004	0.996	0.000
C44.5 Skin of trunk	0.004	0.996	0.000
C15.0 Cervical part of oesophagus	0.004	0.996	0.000
C23 Malignant neoplasm of gallbladder	0.004	0.996	0.000
C17 Malignant neoplasm of small intestine	0.004	0.996	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.996	0.003
R59.9 Enlarged lymph nodes, unspecified	0.003	0.997	0.000
N88 Other noninflammatory disorders of cervix uteri	0.000	0.997	0.003
C71.9 Brain, unspecified	0.000	0.997	0.003
C15.3 Upper third of oesophagus	0.003	0.997	0.000
N88.1 Old laceration of cervix uteri	0.000	0.997	0.003
C71.4 Occipital lobe	0.000	0.997	0.003
H18.9 Disorder of cornea, unspecified	0.000	0.997	0.003
C22.7 Other specified carcinomas of liver	0.003	0.997	0.000
C22.4 Other sarcomas of liver	0.003	0.997	0.000
C22.3 Angiosarcoma of liver	0.003	0.997	0.000
C22.2 Hepatoblastoma	0.003	0.997	0.000
C22.0 Liver cell carcinoma	0.003	0.997	0.000
C22.9 Liver, unspecified	0.003	0.997	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.997	0.003
H18.2 Other corneal oedema	0.000	0.997	0.003
H20 Iridocyclitis	0.000	0.997	0.003
C17.2 Ileum	0.003	0.997	0.000
C17.0 Duodenum	0.003	0.997	0.000
H18 Other disorders of cornea	0.000	0.997	0.003
C71 Malignant neoplasm of brain	0.000	0.997	0.003
C17.9 Small intestine, unspecified	0.003	0.997	0.000
N88.3 Incompetence of cervix uteri	0.000	0.997	0.003
M79.79 Fibromyalgia (Site unspecified)	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.000	0.997	0.003
C17.8 Overlapping lesion of small intestine	0.003	0.997	0.000
C17.3 Meckel's diverticulum	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.997	0.003
H20.1 Chronic iridocyclitis	0.000	0.997	0.003
J32.9 Chronic sinusitis, unspecified	0.000	0.997	0.003
C18.6 Descending colon	0.003	0.997	0.000
K51.4 Pseudopolyposis of colon	0.003	0.997	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.000	0.997	0.003
C21 Malignant neoplasm of anus and anal canal	0.003	0.997	0.000
T51.0 Ethanol	0.000	0.997	0.003
Z80.4 Family history of malignant neoplasm of genital organs	0.003	0.997	0.000
I45.2 Bifascicular block	0.000	0.997	0.003
C26 Malignant neoplasm of other and ill-defined digestive organs	0.003	0.997	0.000
C17.1 Jejunum	0.002	0.997	0.000
C18 Malignant neoplasm of colon	0.003	0.997	0.000
M79.0 Rheumatism, unspecified	0.003	0.997	0.000
C24.8 Overlapping lesion of biliary tract	0.002	0.997	0.000
C24.1 Ampulla of Vater	0.002	0.997	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.997	0.003
C24.0 Extrahepatic bile duct	0.002	0.997	0.000
C71.6 Cerebellum	0.000	0.997	0.002
H20.8 Other iridocyclitis	0.000	0.997	0.002
E21.3 Hyperparathyroidism, unspecified	0.002	0.997	0.000
D10.1 Tongue	0.000	0.997	0.003
C18.2 Ascending colon	0.003	0.997	0.000
C71.3 Parietal lobe	0.000	0.997	0.002
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.002
C71.2 Temporal lobe	0.000	0.997	0.002
N88.0 Leukoplakia of cervix uteri	0.000	0.997	0.002
M79.70 Fibromyalgia (Multiple sites)	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
H18.7 Other corneal deformities	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.998	0.002
C18.3 Hepatic flexure	0.002	0.998	0.000
M79.7 Fibromyalgia	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.000	0.998	0.002
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.998	0.002
C18.1 Appendix	0.002	0.998	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.000	0.998	0.002
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.998	0.002
C21.8 Overlapping lesion of rectum, anus and anal canal	0.002	0.998	0.000
C25.0 Head of pancreas	0.002	0.998	0.000
C26.8 Overlapping lesion of digestive system	0.002	0.998	0.000
C26.1 Spleen	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.998	0.002
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
E11.4 With neurological complications	0.002	0.998	0.000
L53.9 Erythematous condition, unspecified	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.000	0.998	0.002
C18.4 Transverse colon	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.000	0.998	0.002
S82.4 Fracture of fibula alone	0.002	0.998	0.000
Q24.0 Dextrocardia	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
Q82.2 Mastocytosis	0.000	0.998	0.002
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
J38.4 Oedema of larynx	0.000	0.998	0.002
M79.78 Fibromyalgia (Other)	0.002	0.998	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.002	0.998	0.000
M79.76 Fibromyalgia (Lower leg)	0.002	0.998	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.002	0.998	0.000
M79.74 Fibromyalgia (Hand)	0.002	0.998	0.000
M79.73 Fibromyalgia (Forearm)	0.002	0.998	0.000
M79.72 Fibromyalgia (Upper arm)	0.002	0.998	0.000
M79.71 Fibromyalgia (Shoulder region)	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
Q83.1 Accessory breast	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
Q82.5 Congenital nonneoplastic naevus	0.000	0.998	0.002
Q82.0 Hereditary lymphoedema	0.000	0.998	0.002
Q83.8 Other congenital malformations of breast	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
C26.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.998	0.002
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.998	0.002
M96.4 Postsurgical lordosis	0.000	0.998	0.002
M96.3 Postlaminectomy kyphosis	0.000	0.998	0.002
M96.2 Postradiation kyphosis	0.000	0.998	0.002
C21.0 Anus, unspecified	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.000	0.998	0.002
Q82.4 Ectodermal dysplasia (anhidrotic)	0.000	0.998	0.002
Q82.3 Incontinentia pigmenti	0.000	0.998	0.002
Q82.1 Xeroderma pigmentosum	0.000	0.998	0.002
J06.8 Other acute upper respiratory infections of multiple sites	0.000	0.998	0.002
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.998	0.002
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C26.0 Intestinal tract, part unspecified	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
S06 Intracranial injury	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.998	0.002
J06.0 Acute laryngopharyngitis	0.000	0.998	0.002
M96.5 Postradiation scoliosis	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
Q24.6 Congenital heart block	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.998	0.002
Q84 Other congenital malformations of integument	0.000	0.998	0.002
Q81 Epidermolysis bullosa	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.000	0.998	0.002
Q83.2 Absent nipple	0.000	0.998	0.002
Q83.0 Congenital absence of breast with absent nipple	0.000	0.998	0.002
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.998	0.002
O26.8 Other specified pregnancy-related conditions	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.000	0.998	0.002
Q89.3 Situs inversus	0.000	0.998	0.002
S06.3 Focal brain injury	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
J99.0 Rheumatoid lung disease	0.000	0.998	0.002
S02 Fracture of skull and facial bones	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.998	0.002
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.998	0.002
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.998	0.002
Q89.9 Congenital malformation, unspecified	0.000	0.998	0.002
Q89.8 Other specified congenital malformations	0.000	0.998	0.002
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.998	0.002
Q89.4 Conjoined twins	0.000	0.998	0.002
Q89.1 Congenital malformations of adrenal gland	0.000	0.998	0.002
Q89.0 Congenital malformations of spleen	0.000	0.998	0.002
S06.0 Concussion	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
Q83.3 Accessory nipple	0.000	0.998	0.002
Q80 Congenital ichthyosis	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.000	0.998	0.002
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.998	0.001
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.998	0.001
C71.1 Frontal lobe	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.001
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.000	0.998	0.001
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.998	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.001	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.000	0.998	0.001
S02.0 Fracture of vault of skull	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.998	0.001
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.001	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.998	0.001
C69.6 Orbit	0.000	0.998	0.001
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.001
S06.8 Other intracranial injuries	0.001	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
Q81.9 Epidermolysis bullosa, unspecified	0.000	0.998	0.001
Q81.8 Other epidermolysis bullosa	0.000	0.998	0.001
Q81.2 Epidermolysis bullosa dystrophica	0.000	0.998	0.001
Q81.1 Epidermolysis bullosa letalis	0.000	0.998	0.001
Q81.0 Epidermolysis bullosa simplex	0.000	0.998	0.001
Q84.9 Congenital malformation of integument, unspecified	0.000	0.998	0.001
Q84.8 Other specified congenital malformations of integument	0.000	0.998	0.001
Q84.6 Other congenital malformations of nails	0.000	0.998	0.001
Q84.5 Enlarged and hypertrophic nails	0.000	0.998	0.001
Q84.4 Congenital leukonychia	0.000	0.998	0.001
Q84.3 Anonychia	0.000	0.998	0.001
Q84.2 Other congenital malformations of hair	0.000	0.998	0.001
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.000	0.998	0.001
Q84.0 Congenital alopecia	0.000	0.998	0.001
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.000	0.998	0.001
Q86.2 Dysmorphism due to warfarin	0.000	0.998	0.001
Q86.1 Foetal hydantoin syndrome	0.000	0.998	0.001
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.000	0.998	0.001
S02.8 Fractures of other skull and facial bones	0.001	0.998	0.000
S06.2 Diffuse brain injury	0.001	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
C69.4 Ciliary body	0.000	0.998	0.001
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.001	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.000	0.998	0.001
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.001
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.001	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.998	0.001
C25.2 Tail of pancreas	0.001	0.998	0.000
C25.1 Body of pancreas	0.001	0.998	0.001
Q80.8 Other congenital ichthyosis	0.000	0.998	0.001
Q80.4 Harlequin foetus	0.000	0.998	0.001
Q80.3 Congenital bullous ichthyosiform erythroderma	0.000	0.998	0.001
Q80.2 Lamellar ichthyosis	0.000	0.998	0.001
Q80.1 X-linked ichthyosis	0.000	0.998	0.001
Q80.0 Ichthyosis vulgaris	0.000	0.998	0.001
Q85.1 Tuberous sclerosis	0.000	0.998	0.001
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
C18.5 Splenic flexure	0.001	0.999	0.000
Q21.3 Tetralogy of Fallot	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.999	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.999	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.999	0.001
Q23.2 Congenital mitral stenosis	0.000	0.999	0.001
Q27 Other congenital malformations of peripheral vascular system	0.000	0.999	0.001
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.999	0.000
C69.2 Retina	0.000	0.999	0.001
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.999	0.001
K07.3 Anomalies of tooth position	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.000	0.999	0.001
R45.8 Other symptoms and signs involving emotional state	0.001	0.999	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.999	0.001
M94.26 Chondromalacia (Lower leg)	0.000	0.999	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.999	0.000
L50.0 Allergic urticaria	0.000	0.999	0.001
Q96.9 Turner's syndrome, unspecified	0.000	0.999	0.001
Q26 Congenital malformations of great veins	0.000	0.999	0.001
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.999	0.001
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.999	0.001
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.999	0.000
H21.4 Pupillary membranes	0.000	0.999	0.001
Q25.3 Stenosis of aorta	0.000	0.999	0.001
Z73.3 Stress, not elsewhere classified	0.001	0.999	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.999	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.999	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.999	0.001
H22.1 Iridocyclitis in other diseases classified elsewhere	0.000	0.999	0.001
K83.9 Disease of biliary tract, unspecified	0.001	0.999	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.999	0.001
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.999	0.001
Q80.9 Congenital ichthyosis, unspecified	0.000	0.999	0.001
T18.1 Foreign body in oesophagus	0.000	0.999	0.001
Z93.6 Other artificial openings of urinary tract status	0.001	0.999	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.999	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.999	0.001
C69.5 Lachrymal gland and duct	0.000	0.999	0.001
C69.1 Cornea	0.000	0.999	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.999	0.001
H18.5 Hereditary corneal dystrophies	0.000	0.999	0.001
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
N87.1 Moderate cervical dysplasia	0.000	0.999	0.001
S06.9 Intracranial injury, unspecified	0.001	0.999	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.999	0.001
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.999	0.001
T79.4 Traumatic shock	0.001	0.999	0.000
H17 Corneal scars and opacities	0.000	0.999	0.001
Q25 Congenital malformations of great arteries	0.000	0.999	0.001
T79 Certain early complications of trauma, not elsewhere classified	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.999	0.000
C69.9 Eye, unspecified	0.000	0.999	0.001
C69.0 Conjunctiva	0.000	0.999	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.999	0.001
Q21.8 Other congenital malformations of cardiac septa	0.000	0.999	0.001
S02.01 Fracture of vault of skull (open)	0.001	0.999	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.999	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.000	0.999	0.001
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.999	0.001
K02.9 Dental caries, unspecified	0.001	0.999	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.999	0.001
Q27.4 Congenital phlebectasia	0.000	0.999	0.001
Q27.2 Other congenital malformations of renal artery	0.000	0.999	0.001
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.999	0.001
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.999	0.001
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.999	0.001
S92.0 Fracture of calcaneus	0.001	0.999	0.000
I33 Acute and subacute endocarditis	0.000	0.999	0.001
Q96 Turner's syndrome	0.000	0.999	0.001
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.999	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.999	0.000
Q21.4 Aortopulmonary septal defect	0.000	0.999	0.001
Q21.2 Atrioventricular septal defect	0.000	0.999	0.001
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.999	0.001
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.999	0.001
Q26.8 Other congenital malformations of great veins	0.000	0.999	0.001
Q26.6 Portal vein-hepatic artery fistula	0.000	0.999	0.001
Q26.5 Anomalous portal venous connexion	0.000	0.999	0.001
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.999	0.001
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.999	0.001
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.999	0.001
Q26.1 Persistent left superior vena cava	0.000	0.999	0.001
Q26.0 Congenital stenosis of vena cava	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations