TreeWAS – Variant ID: rs2227139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.000	1.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.000	1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
L40 Psoriasis	0.000	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
M06.3 Rheumatoid nodule	0.000	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.999	0.001	0.000
J45.9 Asthma, unspecified	0.000	0.001	0.999
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.003	0.997
E27 Other disorders of adrenal gland	0.997	0.003	0.000
D80-D89 Certain disorders involving the immune mechanism	0.997	0.003	0.000
D69 Purpura and other haemorrhagic conditions	0.996	0.004	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.004	0.996
E27.1 Primary adrenocortical insufficiency	0.995	0.005	0.000
D50-D53 Nutritional anaemias	0.995	0.005	0.000
# Top node	0.994	0.006	0.000
Chapter VI Diseases of the nervous system	0.994	0.006	0.000
D68 Other coagulation defects	0.994	0.006	0.000
L40.5 Arthropathic psoriasis	0.000	0.006	0.994
D86 Sarcoidosis	0.993	0.007	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.008	0.992
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.009	0.991
M07 Psoriatic and enteropathic arthropathies	0.000	0.010	0.990
K90 Intestinal malabsorption	0.989	0.011	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.013	0.987
Chapter XII Diseases of the skin and subcutaneous tissue	0.986	0.014	0.000
D51 Vitamin B12 deficiency anaemia	0.985	0.015	0.000
M07.3 Other psoriatic arthropathies	0.000	0.016	0.984
L20-L30 Dermatitis and eczema	0.982	0.018	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.021	0.979
D69.6 Thrombocytopenia, unspecified	0.978	0.022	0.000
D86.9 Sarcoidosis, unspecified	0.966	0.034	0.000
L27 Dermatitis due to substances taken internally	0.966	0.034	0.000
K90.9 Intestinal malabsorption, unspecified	0.961	0.039	0.000
D86.0 Sarcoidosis of lung	0.957	0.043	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.044	0.956
G20-G26 Extrapyramidal and movement disorders	0.956	0.044	0.000
G37 Other demyelinating diseases of central nervous system	0.955	0.045	0.000
E22 Hyperfunction of pituitary gland	0.953	0.047	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.952	0.048	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.950	0.050	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.050	0.950
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.948	0.052	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.055	0.945
D52 Folate deficiency anaemia	0.945	0.055	0.000
L10-L14 Bullous disorders	0.943	0.057	0.000
Chapter I Certain infectious and parasitic diseases	0.938	0.062	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.937	0.063	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.064	0.936
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.932	0.068	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.068	0.932
D55-D59 Haemolytic anaemias	0.928	0.072	0.000
E34 Other endocrine disorders	0.925	0.075	0.000
L50-L54 Urticaria and erythema	0.923	0.077	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.080	0.920
M06.4 Inflammatory polyarthropathy	0.000	0.088	0.912
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.088	0.912
B37.8 Candidiasis of other sites	0.912	0.088	0.000
D68.8 Other specified coagulation defects	0.911	0.089	0.000
B35-B49 Mycoses	0.910	0.090	0.000
D52.9 Folate deficiency anaemia, unspecified	0.910	0.090	0.000
L13 Other bullous disorders	0.909	0.091	0.000
B37 Candidiasis	0.904	0.096	0.000
L21 Seborrhoeic dermatitis	0.899	0.101	0.000
E27.2 Addisonian crisis	0.896	0.104	0.000
E22.0 Acromegaly and pituitary gigantism	0.895	0.105	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.107	0.893
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.108	0.892
D59 Acquired haemolytic anaemia	0.886	0.114	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.885	0.115	0.000
D69.4 Other primary thrombocytopenia	0.884	0.116	0.000
L13.0 Dermatitis herpetiformis	0.884	0.116	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.883	0.117	0.000
D68.5 Primary Thrombophilia	0.882	0.118	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.120	0.880
L40.0 Psoriasis vulgaris	0.000	0.120	0.880
G20 Parkinson's disease	0.879	0.121	0.000
L40-L45 Papulosquamous disorders	0.077	0.126	0.797
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.126	0.874
G80-G83 Cerebral palsy and other paralytic syndromes	0.870	0.130	0.000
B07 Viral warts	0.869	0.131	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.132	0.868
M35.0 Sicca syndrome [Sjogren]	0.866	0.134	0.000
G25 Other extrapyramidal and movement disorders	0.864	0.136	0.000
D68.0 Von Willebrand's disease	0.863	0.137	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.138	0.862
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.140	0.860
D69.5 Secondary thrombocytopenia	0.859	0.141	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.859	0.141	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.857	0.143	0.000
D60-D64 Aplastic and other anaemias	0.852	0.148	0.000
L53 Other erythematous conditions	0.847	0.153	0.000
D59.1 Other autoimmune haemolytic anaemias	0.847	0.153	0.000
B25-B34 Other viral diseases	0.844	0.156	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.158	0.842
E20 Hypoparathyroidism	0.842	0.158	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.839	0.161	0.000
E34.0 Carcinoid syndrome	0.839	0.161	0.000
L23 Allergic contact dermatitis	0.834	0.166	0.000
D68.6 Other Thrombophilia	0.830	0.170	0.000
L40.8 Other psoriasis	0.000	0.171	0.829
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.171	0.829
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.172	0.828
B25 Cytomegaloviral disease	0.817	0.183	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.184	0.816
E07 Other disorders of thyroid	0.816	0.184	0.000
Chapter IX Diseases of the circulatory system	0.815	0.185	0.000
D61 Other aplastic anaemias	0.813	0.187	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.811	0.189	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.810	0.190	0.000
I60-I69 Cerebrovascular diseases	0.810	0.190	0.000
E40-E46 Malnutrition	0.810	0.190	0.000
G81 Hemiplegia	0.809	0.191	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.191	0.809
D69.8 Other specified haemorrhagic conditions	0.806	0.194	0.000
E04 Other non-toxic goitre	0.805	0.195	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.802	0.198	0.000
C82.0 Small cleaved cell, follicular	0.000	0.198	0.802
E28 Ovarian dysfunction	0.801	0.199	0.000
I63 Cerebral infarction	0.800	0.200	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.799	0.201	0.000
K90.8 Other intestinal malabsorption	0.799	0.201	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.203	0.797
D89.9 Disorder involving the immune mechanism, unspecified	0.796	0.204	0.000
L40.1 Generalised pustular psoriasis	0.000	0.208	0.792
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.792	0.208	0.000
D86.3 Sarcoidosis of skin	0.791	0.209	0.000
E31 Polyglandular dysfunction	0.790	0.210	0.000
B25.9 Cytomegaloviral disease, unspecified	0.790	0.210	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.211	0.789
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.211	0.789
A80-A89 Viral infections of the central nervous system	0.789	0.211	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.213	0.787
E22.9 Hyperfunction of pituitary gland, unspecified	0.786	0.214	0.000
M14.6 Neuropathic arthropathy	0.000	0.218	0.782
D68.1 Hereditary factor XI deficiency	0.779	0.221	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.779	0.221	0.000
M11 Other crystal arthropathies	0.000	0.221	0.779
L11 Other acantholytic disorders	0.778	0.222	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.775	0.225	0.000
G81.9 Hemiplegia, unspecified	0.774	0.226	0.000
E50-E64 Other nutritional deficiencies	0.774	0.226	0.000
I73 Other peripheral vascular diseases	0.774	0.226	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.773	0.227	0.000
L53.9 Erythematous condition, unspecified	0.771	0.229	0.000
I73.0 Raynaud's syndrome	0.771	0.229	0.000
D61.9 Aplastic anaemia, unspecified	0.770	0.230	0.000
E07.8 Other specified disorders of thyroid	0.769	0.231	0.000
I62 Other nontraumatic intracranial haemorrhage	0.769	0.231	0.000
E04.0 Non-toxic diffuse goitre	0.768	0.232	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.233	0.767
L26 Exfoliative dermatitis	0.762	0.238	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.761	0.239	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.756	0.244	0.000
D68.9 Coagulation defect, unspecified	0.756	0.244	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.755	0.245	0.000
A65-A69 Other spirochaetal diseases	0.755	0.245	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.754	0.246	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.753	0.247	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.751	0.249	0.000
E34.8 Other specified endocrine disorders	0.750	0.250	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.748	0.252	0.000
Chapter XXII Codes for special purposes	0.745	0.255	0.000
L25 Unspecified contact dermatitis	0.745	0.255	0.000
L52 Erythema nodosum	0.743	0.257	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.735	0.265	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.734	0.266	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.266	0.734
L20 Atopic dermatitis	0.734	0.266	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.733	0.267	0.000
D68.2 Hereditary deficiency of other clotting factors	0.732	0.268	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.731	0.269	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.731	0.269	0.000
E20.9 Hypoparathyroidism, unspecified	0.729	0.271	0.000
L50 Urticaria	0.729	0.271	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.726	0.274	0.000
E27.9 Disorder of adrenal gland, unspecified	0.725	0.275	0.000
B37.2 Candidiasis of skin and nail	0.723	0.277	0.000
D89.1 Cryoglobulinaemia	0.723	0.277	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.722	0.278	0.000
L30 Other dermatitis	0.720	0.280	0.000
D64 Other anaemias	0.720	0.280	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.283	0.717
M08 Juvenile arthritis	0.000	0.283	0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.717
M05.1 Rheumatoid lung disease	0.000	0.283	0.717
M05.0 Felty's syndrome	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.283	0.000
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
D51.8 Other vitamin B12 deficiency anaemias	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.284	0.716
M06.38 Rheumatoid nodule (Other)	0.000	0.284	0.716
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.284	0.716
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.284	0.716
M06.33 Rheumatoid nodule (Forearm)	0.000	0.284	0.716
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.284	0.716
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.284	0.716
G24 Dystonia	0.716	0.284	0.000
M12 Other specific arthropathies	0.000	0.284	0.715
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
D81 Combined immunodeficiencies	0.715	0.285	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.286	0.714
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.286	0.714
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.286	0.714
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.286	0.714
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.286	0.714
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.286	0.714
M07.5 Arthropathy in ulcerative colitis	0.000	0.290	0.710
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.290	0.710
M07.2 Psoriatic spondylitis	0.000	0.290	0.710
M07.1 Arthritis mutilans	0.000	0.290	0.710
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.290	0.710
Chapter XVI Certain conditions originating in the perinatal period	0.709	0.291	0.000
K90.3 Pancreatic steatorrhoea	0.709	0.291	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.709	0.291	0.000
K90.1 Tropical sprue	0.709	0.291	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.708	0.292	0.000
D69.0 Allergic purpura	0.708	0.292	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.293	0.706
D51.2 Transcobalamin II deficiency	0.706	0.294	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.706	0.294	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.294	0.706
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.294	0.706
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.294	0.706
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.294	0.706
L24 Irritant contact dermatitis	0.704	0.296	0.000
L22 Diaper [napkin] dermatitis	0.704	0.296	0.000
L43 Lichen planus	0.024	0.296	0.680
B15-B19 Viral hepatitis	0.702	0.298	0.000
A86 Unspecified viral encephalitis	0.701	0.299	0.000
D61.0 Constitutional aplastic anaemia	0.700	0.300	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.699	0.301	0.000
M45 Ankylosing spondylitis	0.000	0.303	0.697
G25.0 Essential tremor	0.695	0.305	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.692	0.308	0.000
L27.8 Dermatitis due to other substances taken internally	0.692	0.308	0.000
D64.8 Other specified anaemias	0.692	0.308	0.000
L53.0 Toxic erythema	0.690	0.310	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.311	0.689
D67 Hereditary factor IX deficiency	0.688	0.312	0.000
I63.9 Cerebral infarction, unspecified	0.687	0.313	0.000
M05.2 Rheumatoid vasculitis	0.000	0.314	0.686
E27.4 Other and unspecified adrenocortical insufficiency	0.686	0.314	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.685	0.315	0.000
G22 Parkinsonism in diseases classified elsewhere	0.685	0.315	0.000
G37.5 Concentric sclerosis [Balo]	0.685	0.315	0.000
G37.4 Subacute necrotising myelitis	0.685	0.315	0.000
G37.2 Central pontine myelinolysis	0.685	0.315	0.000
G37.1 Central demyelination of corpus callosum	0.685	0.315	0.000
G37.0 Diffuse sclerosis	0.685	0.315	0.000
D82 Immunodeficiency associated with other major defects	0.685	0.315	0.000
I77 Other disorders of arteries and arterioles	0.685	0.315	0.000
L30.8 Other specified dermatitis	0.684	0.316	0.000
E22.8 Other hyperfunction of pituitary gland	0.683	0.317	0.000
M07.6 Other enteropathic arthropathies	0.000	0.318	0.682
L23.9 Allergic contact dermatitis, unspecified cause	0.682	0.318	0.000
G21 Secondary Parkinsonism	0.682	0.318	0.000
A63.0 Anogenital (venereal) warts	0.681	0.319	0.000
B01 Varicella [chickenpox]	0.681	0.319	0.000
L42 Pityriasis rosea	0.041	0.320	0.638
L27.2 Dermatitis due to ingested food	0.679	0.321	0.000
E34.9 Endocrine disorder, unspecified	0.679	0.321	0.000
D52.8 Other folate deficiency anaemias	0.678	0.322	0.000
D52.1 Drug-induced folate deficiency anaemia	0.678	0.322	0.000
D52.0 Dietary folate deficiency anaemia	0.678	0.322	0.000
D53 Other nutritional anaemias	0.678	0.322	0.000
D57 Sickle-cell disorders	0.677	0.323	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.324	0.676
L14 Bullous disorders in diseases classified elsewhere	0.676	0.324	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.676	0.324	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.675	0.324	0.000
D83 Common variable immunodeficiency	0.675	0.325	0.000
I77.1 Stricture of artery	0.674	0.326	0.000
E46 Unspecified protein-energy malnutrition	0.674	0.326	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.673	0.327	0.000
Q60-Q64 Congenital malformations of the urinary system	0.673	0.327	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.672	0.328	0.000
A75-A79 Rickettsioses	0.672	0.328	0.000
A70-A74 Other diseases caused by chlamydiae	0.672	0.328	0.000
D89.3 Immune reconstitution syndrome	0.672	0.328	0.000
D68.4 Acquired coagulation factor deficiency	0.672	0.328	0.000
D86.1 Sarcoidosis of lymph nodes	0.671	0.329	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.329	0.671
C82.5 Diffuse follicle centre lymphoma	0.000	0.329	0.671
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.333	0.667
L23.5 Allergic contact dermatitis due to other chemical products	0.666	0.334	0.000
L10 Pemphigus	0.666	0.334	0.000
A20-A28 Certain zoonotic bacterial diseases	0.665	0.335	0.000
D55 Anaemia due to enzyme disorders	0.665	0.335	0.000
D86.8 Sarcoidosis of other and combined sites	0.664	0.336	0.000
B65-B83 Helminthiases	0.664	0.336	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.663	0.337	0.000
E34.5 Androgen resistance syndrome	0.663	0.337	0.000
E34.4 Constitutional tall stature	0.663	0.337	0.000
E34.3 Short stature, not elsewhere classified	0.663	0.337	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.663	0.337	0.000
E34.1 Other hypersecretion of intestinal hormones	0.663	0.337	0.000
L54 Erythema in diseases classified elsewhere	0.661	0.338	0.000
E04.2 Non-toxic multinodular goitre	0.662	0.338	0.000
B37.7 Candidal septicaemia	0.661	0.339	0.000
I71 Aortic aneurysm and dissection	0.661	0.339	0.000
L28 Lichen simplex chronicus and prurigo	0.661	0.339	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.659	0.341	0.000
G25.2 Other specified forms of tremor	0.659	0.341	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.655	0.345	0.000
G30-G32 Other degenerative diseases of the nervous system	0.654	0.346	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.346	0.654
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.346	0.654
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.346	0.654
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.346	0.654
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.346	0.654
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.346	0.654
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.346	0.654
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.346	0.654
D56 Thalassaemia	0.653	0.347	0.000
L11.0 Acquired keratosis follicularis	0.653	0.347	0.000
G82 Paraplegia and tetraplegia	0.653	0.347	0.000
B48 Other mycoses, not elsewhere classified	0.652	0.347	0.000
B47 Mycetoma	0.652	0.347	0.000
B46 Zygomycosis	0.652	0.347	0.000
B45 Cryptococcosis	0.652	0.347	0.000
B43 Chromomycosis and phaeomycotic abscess	0.652	0.347	0.000
B42 Sporotrichosis	0.652	0.347	0.000
B41 Paracoccidioidomycosis	0.652	0.347	0.000
B40 Blastomycosis	0.652	0.347	0.000
B39 Histoplasmosis	0.652	0.347	0.000
B38 Coccidioidomycosis	0.652	0.347	0.000
M11.2 Other chondrocalcinosis	0.000	0.348	0.652
L13.9 Bullous disorder, unspecified	0.651	0.348	0.000
L13.8 Other specified bullous disorders	0.651	0.348	0.000
L13.1 Subcorneal pustular dermatitis	0.651	0.348	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.651	0.349	0.000
B37.6 Candidal endocarditis	0.648	0.352	0.000
B37.5 Candidal meningitis	0.648	0.352	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.648	0.352	0.000
Q43 Other congenital malformations of intestine	0.648	0.352	0.000
M06.1 Adult-onset Still's disease	0.000	0.352	0.647
G36 Other acute disseminated demyelination	0.646	0.354	0.000
B25.0 Cytomegaloviral pneumonitis	0.645	0.354	0.000
L21.8 Other seborrhoeic dermatitis	0.644	0.356	0.000
L21.1 Seborrhoeic infantile dermatitis	0.644	0.356	0.000
L21.0 Seborrhoea capitis	0.644	0.356	0.000
L50.1 Idiopathic urticaria	0.644	0.356	0.000
G25.1 Drug-induced tremor	0.643	0.356	0.000
E28.3 Primary ovarian failure	0.643	0.357	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.643	0.357	0.000
D69.2 Other nonthrombocytopenic purpura	0.642	0.358	0.000
G25.5 Other chorea	0.641	0.359	0.000
D69.1 Qualitative platelet defects	0.640	0.359	0.000
E31.0 Autoimmune polyglandular failure	0.640	0.360	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.639	0.361	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.362	0.637
D59.8 Other acquired haemolytic anaemias	0.636	0.364	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.636	0.364	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.636	0.364	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.636	0.364	0.000
D59.3 Haemolytic-uraemic syndrome	0.636	0.364	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.636	0.364	0.000
G23 Other degenerative diseases of basal ganglia	0.635	0.365	0.000
B06 Rubella [German measles]	0.635	0.365	0.000
B05 Measles	0.635	0.365	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.635	0.365	0.000
B04 Monkeypox	0.635	0.365	0.000
B03 Smallpox	0.635	0.365	0.000
G83 Other paralytic syndromes	0.633	0.367	0.000
E29 Testicular dysfunction	0.631	0.368	0.000
B37.9 Candidiasis, unspecified	0.631	0.368	0.000
Q40 Other congenital malformations of upper alimentary tract	0.631	0.369	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.629	0.371	0.000
G24.9 Dystonia, unspecified	0.629	0.371	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.627	0.373	0.000
L41 Parapsoriasis	0.056	0.373	0.571
L45 Papulosquamous disorders in diseases classified elsewhere	0.056	0.373	0.571
Q00-Q07 Congenital malformations of the nervous system	0.625	0.375	0.000
G57 Mononeuropathies of lower limb	0.625	0.375	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.624	0.376	0.000
A69 Other spirochaetal infections	0.624	0.376	0.000
C82.2 Large cell, follicular	0.000	0.376	0.624
Q44.6 Cystic disease of liver	0.623	0.377	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.622	0.378	0.000
E27.8 Other specified disorders of adrenal gland	0.620	0.380	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.619	0.381	0.000
G25.4 Drug-induced chorea	0.619	0.381	0.000
D69.9 Haemorrhagic condition, unspecified	0.616	0.384	0.000
D84 Other immunodeficiencies	0.615	0.385	0.000
D66 Hereditary factor VIII deficiency	0.615	0.385	0.000
E55 Vitamin D deficiency	0.614	0.386	0.000
B36 Other superficial mycoses	0.614	0.386	0.000
B50-B64 Protozoal diseases	0.613	0.387	0.000
L44 Other papulosquamous disorders	0.056	0.387	0.557
L51 Erythema multiforme	0.613	0.387	0.000
I70 Atherosclerosis	0.613	0.387	0.000
E22.1 Hyperprolactinaemia	0.612	0.388	0.000
I00-I02 Acute rheumatic fever	0.611	0.389	0.000
A80 Acute poliomyelitis	0.610	0.390	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.609	0.391	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.392	0.608
L53.3 Other chronic figurate erythema	0.607	0.392	0.000
L53.2 Erythema marginatum	0.607	0.392	0.000
L53.1 Erythema annulare centrifugum	0.607	0.392	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.606	0.394	0.000
B30 Viral conjunctivitis	0.605	0.395	0.000
B26 Mumps	0.605	0.395	0.000
B37.4 Candidiasis of other urogenital sites	0.605	0.395	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.396	0.604
M14.4 Arthropathy in amyloidosis	0.000	0.396	0.604
M14.3 Lipoid dermatoarthritis	0.000	0.396	0.604
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.396	0.604
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.396	0.604
E20.8 Other hypoparathyroidism	0.604	0.396	0.000
E20.1 Pseudohypoparathyroidism	0.604	0.396	0.000
E20.0 Idiopathic hypoparathyroidism	0.604	0.396	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.602	0.398	0.000
B37.1 Pulmonary candidiasis	0.601	0.398	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.399	0.601
G00 Bacterial meningitis, not elsewhere classified	0.600	0.400	0.000
Q60.0 Renal agenesis, unilateral	0.600	0.400	0.000
D58 Other hereditary haemolytic anaemias	0.599	0.401	0.000
L23.8 Allergic contact dermatitis due to other agents	0.598	0.402	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.598	0.402	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.598	0.402	0.000
L23.4 Allergic contact dermatitis due to dyes	0.598	0.402	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.598	0.402	0.000
L23.0 Allergic contact dermatitis due to metals	0.598	0.402	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.598	0.402	0.000
B25.8 Other cytomegaloviral diseases	0.597	0.403	0.000
I63.8 Other cerebral infarction	0.597	0.403	0.000
E28.2 Polycystic ovarian syndrome	0.596	0.404	0.000
E61 Deficiency of other nutrient elements	0.596	0.404	0.000
B49 Unspecified mycosis	0.593	0.407	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.593	0.407	0.000
G82.1 Spastic paraplegia	0.593	0.407	0.000
L55 Sunburn	0.592	0.408	0.000
E05.8 Other thyrotoxicosis	0.591	0.409	0.000
G25.3 Myoclonus	0.589	0.411	0.000
E21.0 Primary hyperparathyroidism	0.589	0.411	0.000
L53.8 Other specified erythematous conditions	0.589	0.411	0.000
A15-A19 Tuberculosis	0.588	0.412	0.000
B19 Unspecified viral hepatitis	0.586	0.414	0.000
B25.2 Cytomegaloviral pancreatitis	0.586	0.414	0.000
B25.1 Cytomegaloviral hepatitis	0.586	0.414	0.000
B00 Herpesviral [herpes simplex] infections	0.585	0.415	0.000
E07.1 Dyshormogenetic goitre	0.585	0.415	0.000
E07.0 Hypersecretion of calcitonin	0.585	0.415	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.417	0.583
E53 Deficiency of other B group vitamins	0.583	0.417	0.000
D61.8 Other specified aplastic anaemias	0.583	0.417	0.000
D61.3 Idiopathic aplastic anaemia	0.583	0.417	0.000
D61.2 Aplastic anaemia due to other external agents	0.583	0.417	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.583	0.417	0.000
E21.3 Hyperparathyroidism, unspecified	0.582	0.418	0.000
A59 Trichomoniasis	0.581	0.419	0.000
A56 Other sexually transmitted chlamydial diseases	0.581	0.419	0.000
A54 Gonococcal infection	0.581	0.419	0.000
A53 Other and unspecified syphilis	0.581	0.419	0.000
A52 Late syphilis	0.581	0.419	0.000
A51 Early syphilis	0.581	0.419	0.000
A50 Congenital syphilis	0.581	0.419	0.000
A64 Unspecified sexually transmitted disease	0.581	0.419	0.000
A58 Granuloma inguinale	0.581	0.419	0.000
A57 Chancroid	0.581	0.419	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.581	0.419	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.580	0.419	0.000
E45 Retarded development following protein-energy malnutrition	0.580	0.419	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations