TreeWAS – Variant ID: rs2237886

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.807	0.193
F41 Other anxiety disorders	0.000	0.953	0.047
F41.1 Generalised anxiety disorder	0.000	0.961	0.039
F41.8 Other specified anxiety disorders	0.000	0.966	0.034
F41.3 Other mixed anxiety disorders	0.000	0.966	0.034
R03.1 Nonspecific low blood-pressure reading	0.000	0.975	0.025
H02.8 Other specified disorders of eyelid	0.021	0.979	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.979	0.021
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.980	0.020
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.980	0.020
F41.9 Anxiety disorder, unspecified	0.000	0.984	0.016
I08.0 Disorders of both mitral and aortic valves	0.000	0.989	0.011
R41.3 Other amnesia	0.010	0.990	0.000
R16.1 Splenomegaly, not elsewhere classified	0.009	0.991	0.000
H53.0 Amblyopia ex anopsia	0.009	0.991	0.000
H53 Visual disturbances	0.008	0.992	0.000
H53.1 Subjective visual disturbances	0.008	0.992	0.000
H53.4 Visual field defects	0.007	0.993	0.000
H53.9 Visual disturbance, unspecified	0.007	0.993	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.993	0.007
N90.7 Vulvar cyst	0.000	0.993	0.007
N39.3 Stress incontinence	0.000	0.994	0.006
K05.3 Chronic periodontitis	0.006	0.994	0.000
H53.6 Night blindness	0.006	0.994	0.000
H53.5 Colour vision deficiencies	0.006	0.994	0.000
H53.3 Other disorders of binocular vision	0.006	0.994	0.000
K07 Dentofacial anomalies [including malocclusion]	0.006	0.994	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.006	0.994	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.994	0.006
K05 Gingivitis and periodontal diseases	0.005	0.995	0.000
K07.3 Anomalies of tooth position	0.005	0.995	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.005	0.995	0.000
K08 Other disorders of teeth and supporting structures	0.005	0.995	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.005	0.995	0.000
H53.8 Other visual disturbances	0.005	0.995	0.000
K07.9 Dentofacial anomaly, unspecified	0.005	0.995	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.005	0.995	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.005	0.995	0.000
K07.6 Temporomandibular joint disorders	0.005	0.995	0.000
K00.9 Disorder of tooth development, unspecified	0.005	0.995	0.000
K00 Disorders of tooth development and eruption	0.005	0.995	0.000
K07.4 Malocclusion, unspecified	0.005	0.995	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.995	0.005
K07.8 Other dentofacial anomalies	0.004	0.995	0.000
K07.5 Dentofacial functional abnormalities	0.004	0.995	0.000
K07.0 Major anomalies of jaw size	0.004	0.995	0.000
K11.7 Disturbances of salivary secretion	0.005	0.995	0.000
K11 Diseases of salivary glands	0.005	0.995	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.004	0.995	0.000
I08 Multiple valve diseases	0.000	0.995	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
K05.1 Chronic gingivitis	0.004	0.996	0.000
F42 Obsessive-compulsive disorder	0.000	0.996	0.004
K07.2 Anomalies of dental arch relationship	0.004	0.996	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.996	0.004
K11.8 Other diseases of salivary glands	0.004	0.996	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.004	0.996	0.000
F45 Somatoform disorders	0.000	0.996	0.004
K13 Other diseases of lip and oral mucosa	0.004	0.996	0.000
K05.6 Periodontal disease, unspecified	0.004	0.996	0.000
K05.2 Acute periodontitis	0.004	0.996	0.000
K05.5 Other periodontal diseases	0.004	0.996	0.000
K05.4 Periodontosis	0.004	0.996	0.000
K05.0 Acute gingivitis	0.004	0.996	0.000
K10 Other diseases of jaws	0.004	0.996	0.000
F48 Other neurotic disorders	0.000	0.996	0.004
H53-H54 Visual disturbances and blindness	0.004	0.996	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.004	0.996	0.000
I08.8 Other multiple valve diseases	0.000	0.996	0.004
I12 Hypertensive renal disease	0.000	0.996	0.004
K06 Other disorders of gingiva and edentulous alveolar ridge	0.004	0.996	0.000
K11.9 Disease of salivary gland, unspecified	0.004	0.996	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.004	0.996	0.000
K13.0 Diseases of lips	0.004	0.996	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.996	0.004
K03 Other diseases of hard tissues of teeth	0.004	0.996	0.000
H02 Other disorders of eyelid	0.004	0.996	0.000
K10.8 Other specified diseases of jaws	0.004	0.996	0.000
K08.3 Retained dental root	0.004	0.996	0.000
K11.3 Abscess of salivary gland	0.004	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
F44 Dissociative [conversion] disorders	0.000	0.996	0.003
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
M77.91 Enthesopathy, unspecified (Shoulder region)	0.004	0.996	0.000
K00.8 Other disorders of tooth development	0.003	0.996	0.000
K00.7 Teething syndrome	0.003	0.996	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.003	0.996	0.000
K00.4 Disturbances in tooth formation	0.003	0.996	0.000
K00.3 Mottled teeth	0.003	0.996	0.000
K00.2 Abnormalities of size and form of teeth	0.003	0.996	0.000
K00.1 Supernumerary teeth	0.003	0.996	0.000
K00.0 Anodontia	0.003	0.996	0.000
K12 Stomatitis and related lesions	0.004	0.996	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.996	0.003
K11.4 Fistula of salivary gland	0.003	0.996	0.000
K11.0 Atrophy of salivary gland	0.003	0.996	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.996	0.003
N62 Hypertrophy of breast	0.000	0.996	0.004
F42.8 Other obsessive-compulsive disorders	0.000	0.997	0.003
F42.2 Mixed obsessional thoughts and acts	0.000	0.997	0.003
F42.1 Predominantly compulsive acts [obsessional rituals]	0.000	0.997	0.003
F42.0 Predominantly obsessional thoughts or ruminations	0.000	0.997	0.003
K00.6 Disturbances in tooth eruption	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
H54.4 Blindness, one eye	0.003	0.997	0.000
H02.6 Xanthelasma of eyelid	0.003	0.997	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.003	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
F45.9 Somatoform disorder, unspecified	0.000	0.997	0.003
F45.4 Persistent somatoform pain disorder	0.000	0.997	0.003
F45.2 Hypochondriacal disorder	0.000	0.997	0.003
F45.1 Undifferentiated somatoform disorder	0.000	0.997	0.003
F45.0 Somatisation disorder	0.000	0.997	0.003
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.003	0.997	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.003	0.997	0.000
K13.5 Oral submucous fibrosis	0.003	0.997	0.000
K13.3 Hairy leukoplakia	0.003	0.997	0.000
K13.1 Cheek and lip biting	0.003	0.997	0.000
K10.2 Inflammatory conditions of jaws	0.003	0.997	0.000
F45.3 Somatoform autonomic dysfunction	0.000	0.997	0.003
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
K14 Diseases of tongue	0.003	0.997	0.000
K05.22 Aggressive periodontitis, generalized	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
K11.1 Hypertrophy of salivary gland	0.003	0.997	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.003	0.997	0.000
F48.9 Neurotic disorder, unspecified	0.000	0.997	0.003
F48.8 Other specified neurotic disorders	0.000	0.997	0.003
F48.1 Depersonalisation-derealisation syndrome	0.000	0.997	0.003
K10.9 Disease of jaws, unspecified	0.003	0.997	0.000
K10.3 Alveolitis of jaws	0.003	0.997	0.000
K10.1 Giant cell granuloma, central	0.003	0.997	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.003	0.997	0.000
H02.5 Other disorders affecting eyelid function	0.003	0.997	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.003	0.997	0.000
K06.1 Gingival enlargement	0.003	0.997	0.000
K06.0 Gingival recession	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.997	0.003
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
F48.0 Neurasthenia	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.003	0.997	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.003	0.997	0.000
H02.2 Lagophthalmos	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.003	0.997	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.003	0.997	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.003	0.997	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.003	0.997	0.000
K03.6 Deposits [accretions] on teeth	0.003	0.997	0.000
K03.5 Ankylosis of teeth	0.003	0.997	0.000
K03.4 Hypercementosis	0.003	0.997	0.000
K03.3 Pathological resorption of teeth	0.003	0.997	0.000
K03.2 Erosion of teeth	0.003	0.997	0.000
K03.1 Abrasion of teeth	0.003	0.997	0.000
K03.0 Excessive attrition of teeth	0.003	0.997	0.000
K10.0 Developmental disorders of jaws	0.003	0.997	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.003	0.997	0.000
S27.0 Traumatic pneumothorax	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.997	0.003
F44.8 Other dissociative [conversion] disorders	0.000	0.997	0.003
F44.7 Mixed dissociative [conversion] disorders	0.000	0.997	0.003
F44.6 Dissociative anaesthesia and sensory loss	0.000	0.997	0.003
F44.3 Trance and possession disorders	0.000	0.997	0.003
F44.2 Dissociative stupor	0.000	0.997	0.003
F44.1 Dissociative fugue	0.000	0.997	0.003
F44.0 Dissociative amnesia	0.000	0.997	0.003
K12.1 Other forms of stomatitis	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
K11.6 Mucocele of salivary gland	0.003	0.997	0.000
D25 Leiomyoma of uterus	0.000	0.997	0.003
R41.1 Anterograde amnesia	0.003	0.997	0.000
K12.3 Oral mucositis (ulcerative)	0.003	0.997	0.000
K11.2 Sialoadenitis	0.003	0.997	0.000
R47.1 Dysarthria and anarthria	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
F44.4 Dissociative motor disorders	0.000	0.997	0.002
I05 Rheumatic mitral valve diseases	0.000	0.997	0.003
I05.0 Mitral stenosis	0.000	0.997	0.003
K11.5 Sialolithiasis	0.003	0.997	0.000
K12.0 Recurrent oral aphthae	0.003	0.997	0.000
F40 Phobic anxiety disorders	0.000	0.997	0.002
K13.29 Other disturbances of oral epithelium, including tongue	0.002	0.997	0.000
L28.0 Lichen simplex chronicus	0.003	0.997	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.997	0.000
H54.5 Low vision, one eye	0.002	0.997	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.997	0.000
H54.2 Low vision, both eyes	0.002	0.997	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.997	0.000
K14.6 Glossodynia	0.003	0.997	0.000
K14.5 Plicated tongue	0.003	0.997	0.000
K14.4 Atrophy of tongue papillae	0.003	0.997	0.000
K14.3 Hypertrophy of tongue papillae	0.003	0.997	0.000
K14.2 Median rhomboid glossitis	0.003	0.997	0.000
K14.1 Geographic tongue	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
F43 Reaction to severe stress, and adjustment disorders	0.000	0.997	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
H43.1 Vitreous haemorrhage	0.003	0.997	0.000
N63 Unspecified lump in breast	0.000	0.997	0.003
K14.9 Disease of tongue, unspecified	0.003	0.997	0.000
F44.5 Dissociative convulsions	0.000	0.997	0.002
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.003	0.997	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.997	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.002
H53.2 Diplopia	0.002	0.997	0.000
Q54.9 Hypospadias, unspecified	0.002	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
K09 Cysts of oral region, not elsewhere classified	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
R41.0 Disorientation, unspecified	0.002	0.998	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.002	0.998	0.000
R07.3 Other chest pain	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.000	0.998	0.002
K14.0 Glossitis	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.000	0.998	0.002
F40.1 Social phobias	0.000	0.998	0.002
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.000	0.998	0.002
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.002
F43.8 Other reactions to severe stress	0.000	0.998	0.002
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
K02 Dental caries	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.000	0.998	0.002
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.002	0.998	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.001	0.998	0.001
D25.0 Submucous leiomyoma of uterus	0.000	0.998	0.002
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
K01 Embedded and impacted teeth	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
H43 Disorders of vitreous body	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
N60-N64 Disorders of breast	0.000	0.998	0.002
M77.99 Enthesopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.002	0.998	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.002	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.002	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.002	0.998	0.000
F40.0 Agoraphobia	0.000	0.998	0.001
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
N61 Inflammatory disorders of breast	0.000	0.998	0.002
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.002
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.002
I09.0 Rheumatic myocarditis	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
F43.0 Acute stress reaction	0.000	0.998	0.002
H43.3 Other vitreous opacities	0.002	0.998	0.000
H52.0 Hypermetropia	0.002	0.998	0.000
K02.5 Caries with pulp exposure	0.002	0.998	0.000
K02.4 Odontoclasia	0.002	0.998	0.000
K02.3 Arrested dental caries	0.002	0.998	0.000
K02.2 Caries of cementum	0.002	0.998	0.000
K02.1 Caries of dentin	0.002	0.998	0.000
K02.0 Caries limited to enamel	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.002
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.002
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.998	0.001
I07.8 Other tricuspid valve diseases	0.001	0.998	0.001
I07.2 Tricuspid stenosis with insufficiency	0.001	0.998	0.001
I07.0 Tricuspid stenosis	0.001	0.998	0.001
Q65 Congenital deformities of hip	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.998	0.001
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Z46.8 Fitting and adjustment of other specified devices	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
H43.0 Vitreous prolapse	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
H01 Other inflammation of eyelid	0.002	0.998	0.000
H50.5 Heterophoria	0.002	0.998	0.000
H52.7 Disorder of refraction, unspecified	0.002	0.998	0.000
H52.4 Presbyopia	0.002	0.998	0.000
H52.2 Astigmatism	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.002	0.998	0.000
Q17.5 Prominent ear	0.001	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
H50.8 Other specified strabismus	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.001	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z96.6 Presence of orthopaedic joint implants	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.001	0.998	0.000
N86 Erosion and ectropion of cervix uteri	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.002	0.998	0.000
M71.38 Other bursal cyst (Other)	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.001	0.998	0.000
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.001	0.998	0.000
H01.1 Non-infectious dermatoses of eyelid	0.001	0.998	0.000
H43.8 Other disorders of vitreous body	0.002	0.998	0.000
Q10.7 Congenital malformation of orbit	0.001	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.001	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.001	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.001	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.001	0.998	0.000
Q10.2 Congenital entropion	0.001	0.998	0.000
Q10.1 Congenital ectropion	0.001	0.998	0.000
Q60.6 Potter's syndrome	0.001	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.001	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.998	0.000
Q43.7 Persistent cloaca	0.001	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.001	0.998	0.000
Q43.5 Ectopic anus	0.001	0.998	0.000
Q43.4 Duplication of intestine	0.001	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.001	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.001	0.998	0.000
Q43.1 Hirschsprung's disease	0.001	0.998	0.000
Q67.5 Congenital deformity of spine	0.001	0.998	0.000
Q39 Congenital malformations of oesophagus	0.001	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.001	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.001	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.001	0.998	0.000
Q17.4 Misplaced ear	0.001	0.998	0.000
Q17.3 Other misshapen ear	0.001	0.998	0.000
Q17.2 Microtia	0.001	0.998	0.000
Q17.1 Macrotia	0.001	0.998	0.000
Q17.0 Accessory auricle	0.001	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.001	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.001	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.998	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.001	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.001	0.998	0.000
S10 Superficial injury of neck	0.001	0.998	0.000
K01.0 Embedded teeth	0.001	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.6 Pectus excavatum	0.001	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations