TreeWAS – Variant ID: rs2237896

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.000	0.000	1.000
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
Chapter II Neoplasms	0.989	0.011	0.000
Chapter VI Diseases of the nervous system	0.988	0.012	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.983	0.017	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.021	0.979
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.979	0.021	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.977	0.023	0.000
S00-S09 Injuries to the head	0.976	0.024	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.971	0.029	0.000
Chapter I Certain infectious and parasitic diseases	0.970	0.030	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.963	0.034	0.003
M20-M25 Other joint disorders	0.965	0.035	0.000
E70-E90 Metabolic disorders	0.959	0.040	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.955	0.045	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.947	0.053	0.000
E86 Volume depletion	0.944	0.056	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.933	0.067	0.000
M20 Acquired deformities of fingers and toes	0.932	0.068	0.000
Chapter XX External causes of morbidity and mortality	0.928	0.072	0.000
M20.4 Other hammer toe(s) (acquired)	0.925	0.075	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.924	0.076	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.924	0.076	0.000
S02 Fracture of skull and facial bones	0.919	0.081	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.918	0.082	0.000
G57 Mononeuropathies of lower limb	0.913	0.087	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.906	0.094	0.000
M25 Other joint disorders, not elsewhere classified	0.905	0.095	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.904	0.096	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.900	0.100	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.896	0.104	0.000
E11.3 With ophthalmic complications	0.000	0.105	0.895
A30-A49 Other bacterial diseases	0.895	0.105	0.000
E10-E14 Diabetes mellitus	0.042	0.112	0.846
E87.5 Hyperkalaemia	0.887	0.113	0.000
E11.4 With neurological complications	0.000	0.121	0.879
E87.6 Hypokalaemia	0.879	0.121	0.000
M65-M68 Disorders of synovium and tendon	0.877	0.123	0.000
C77.2 Intra-abdominal lymph nodes	0.873	0.127	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.869	0.131	0.000
S00 Superficial injury of head	0.867	0.133	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.864	0.136	0.000
Chapter V Mental and behavioural disorders	0.860	0.140	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.857	0.143	0.000
C34 Malignant neoplasm of bronchus and lung	0.857	0.143	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.856	0.144	0.000
G90-G99 Other disorders of the nervous system	0.854	0.146	0.000
D45 Polycythaemia vera	0.853	0.147	0.000
W00-W19 Falls	0.851	0.149	0.000
C51-C58 Malignant neoplasms of female genital organs	0.850	0.150	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.848	0.152	0.000
G57.8 Other mononeuropathies of lower limb	0.847	0.153	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.844	0.156	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.842	0.158	0.000
M25.7 Osteophyte	0.840	0.160	0.000
M24 Other specific joint derangements	0.840	0.160	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.839	0.161	0.000
C92 Myeloid leukaemia	0.837	0.163	0.000
Q60-Q64 Congenital malformations of the urinary system	0.837	0.163	0.000
Q50-Q56 Congenital malformations of genital organs	0.833	0.167	0.000
S32 Fracture of lumbar spine and pelvis	0.830	0.170	0.000
G03 Meningitis due to other and unspecified causes	0.826	0.174	0.000
S90-S99 Injuries to the ankle and foot	0.824	0.175	0.000
Chapter XXII Codes for special purposes	0.823	0.177	0.000
B35-B49 Mycoses	0.820	0.180	0.000
G50 Disorders of trigeminal nerve	0.820	0.180	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.819	0.181	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.818	0.182	0.000
S02.1 Fracture of base of skull	0.816	0.184	0.000
D37.5 Rectum	0.809	0.191	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.806	0.194	0.000
T46.1 Calcium-channel blockers	0.806	0.194	0.000
M65 Synovitis and tenosynovitis	0.805	0.195	0.000
S02.6 Fracture of mandible	0.804	0.196	0.000
A41 Other septicaemia	0.803	0.197	0.000
T79-T79 Certain early complications of trauma	0.800	0.200	0.000
E20-E35 Disorders of other endocrine glands	0.795	0.203	0.002
E87.3 Alkalosis	0.797	0.203	0.000
S50-S59 Injuries to the elbow and forearm	0.794	0.206	0.000
S05 Injury of eye and orbit	0.793	0.207	0.000
E10 Insulin-dependent diabetes mellitus	0.011	0.207	0.782
D37.2 Small intestine	0.791	0.209	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.790	0.210	0.000
S01 Open wound of head	0.790	0.210	0.000
S00.1 Contusion of eyelid and periocular area	0.790	0.210	0.000
B15-B19 Viral hepatitis	0.787	0.213	0.000
C34.9 Bronchus or lung, unspecified	0.786	0.214	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.785	0.215	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.785	0.215	0.000
Q80-Q89 Other congenital malformations	0.784	0.216	0.000
B25-B34 Other viral diseases	0.784	0.216	0.000
G51 Facial nerve disorders	0.782	0.218	0.000
C92.1 Chronic myeloid leukaemia	0.780	0.220	0.000
M21 Other acquired deformities of limbs	0.779	0.221	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.778	0.222	0.000
Q00-Q07 Congenital malformations of the nervous system	0.776	0.224	0.000
E87.2 Acidosis	0.776	0.224	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.773	0.227	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.772	0.228	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.771	0.229	0.000
G57.6 Lesion of plantar nerve	0.770	0.230	0.000
W17 Other fall from one level to another	0.769	0.231	0.000
M60-M63 Disorders of muscles	0.768	0.232	0.000
M25.5 Pain in joint	0.767	0.233	0.000
G58 Other mononeuropathies	0.767	0.233	0.000
D46 Myelodysplastic syndromes	0.767	0.233	0.000
M45-M49 Spondylopathies	0.765	0.235	0.000
A41.9 Septicaemia, unspecified	0.765	0.235	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.764	0.236	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.764	0.236	0.000
G03.9 Meningitis, unspecified	0.761	0.239	0.000
M25.8 Other specified joint disorders	0.760	0.240	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.760	0.240	0.000
G40-G47 Episodic and paroxysmal disorders	0.759	0.241	0.000
G82 Paraplegia and tetraplegia	0.756	0.244	0.000
M25.78 Osteophyte (Other)	0.755	0.245	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.754	0.246	0.000
M20.0 Deformity of finger(s)	0.754	0.246	0.000
C34.0 Main bronchus	0.754	0.246	0.000
C80 Malignant neoplasm without specification of site	0.752	0.248	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.752	0.248	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.749	0.251	0.000
E10.9 Without complications	0.001	0.251	0.748
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.748	0.252	0.000
C77.5 Intrapelvic lymph nodes	0.747	0.253	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.747	0.253	0.000
E27 Other disorders of adrenal gland	0.746	0.253	0.001
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.747	0.253	0.000
T36 Poisoning by systemic antibiotics	0.746	0.254	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.744	0.256	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.743	0.257	0.000
S02.10 Fracture of base of skull (closed)	0.742	0.258	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.742	0.258	0.000
A40 Streptococcal septicaemia	0.741	0.259	0.000
W05 Fall involving wheelchair	0.737	0.263	0.000
F30-F39 Mood [affective] disorders	0.737	0.263	0.000
M50-M54 Other dorsopathies	0.736	0.264	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.736	0.264	0.000
D37.1 Stomach	0.736	0.264	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.735	0.265	0.000
E83 Disorders of mineral metabolism	0.734	0.265	0.000
T51 Toxic effect of alcohol	0.732	0.268	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.732	0.268	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.731	0.269	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.731	0.269	0.000
S00.7 Multiple superficial injuries of head	0.731	0.269	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.729	0.271	0.000
S31 Open wound of abdomen, lower back and pelvis	0.728	0.272	0.000
G91 Hydrocephalus	0.727	0.273	0.000
C56 Malignant neoplasm of ovary	0.723	0.277	0.000
G50.0 Trigeminal neuralgia	0.723	0.277	0.000
S02.60 Fracture of mandible (closed)	0.722	0.278	0.000
G00 Bacterial meningitis, not elsewhere classified	0.721	0.279	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.719	0.281	0.000
Q61 Cystic kidney disease	0.718	0.281	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.718	0.282	0.000
C34.8 Overlapping lesion of bronchus and lung	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
S32.0 Fracture of lumbar vertebra	0.717	0.283	0.000
C79 Secondary malignant neoplasm of other sites	0.716	0.284	0.000
A46 Erysipelas	0.716	0.284	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.284	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.714	0.286	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.714	0.286	0.000
E11.5 With peripheral circulatory complications	0.000	0.287	0.713
Q54 Hypospadias	0.713	0.287	0.000
W08 Fall involving other furniture	0.713	0.287	0.000
C77.0 Lymph nodes of head, face and neck	0.713	0.287	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.713	0.287	0.000
M25.57 Pain in joint (Ankle and foot)	0.712	0.288	0.000
C77.1 Intrathoracic lymph nodes	0.712	0.288	0.000
S36 Injury of intra-abdominal organs	0.712	0.288	0.000
S00.3 Superficial injury of nose	0.711	0.289	0.000
B07 Viral warts	0.710	0.290	0.000
E85 Amyloidosis	0.710	0.290	0.000
G96 Other disorders of central nervous system	0.709	0.291	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.709	0.291	0.000
G70-G73 Diseases of myoneural junction and muscle	0.709	0.291	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.708	0.292	0.000
W50-W64 Exposure to animate mechanical forces	0.707	0.293	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.707	0.293	0.000
M80-M85 Disorders of bone density and structure	0.706	0.294	0.000
C77.9 Lymph node, unspecified	0.705	0.295	0.000
E11.1 With ketoacidosis	0.000	0.297	0.703
S01.8 Open wound of other parts of head	0.702	0.298	0.000
E11.8 With unspecified complications	0.000	0.298	0.702
E11.7 With multiple complications	0.000	0.298	0.702
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.702	0.298	0.000
Q35-Q37 Cleft lip and cleft palate	0.702	0.298	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.702	0.298	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.701	0.299	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.701	0.299	0.000
S56 Injury of muscle and tendon at forearm level	0.700	0.300	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.700	0.300	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.700	0.300	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.700	0.300	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.700	0.300	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.700	0.300	0.000
M91-M94 Chondropathies	0.700	0.300	0.000
C32 Malignant neoplasm of larynx	0.700	0.300	0.000
S08 Traumatic amputation of part of head	0.700	0.300	0.000
S07 Crushing injury of head	0.700	0.300	0.000
S04 Injury of cranial nerves	0.700	0.300	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.700	0.300	0.000
F60-F69 Disorders of adult personality and behaviour	0.700	0.300	0.000
T39.0 Salicylates	0.699	0.301	0.000
T91 Sequelae of injuries of neck and trunk	0.699	0.301	0.000
X60-X84 Intentional self-harm	0.699	0.301	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.698	0.302	0.000
E11.6 With other specified complications	0.000	0.303	0.696
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.696	0.303	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.696	0.303	0.000
Chapter VIII Diseases of the ear and mastoid process	0.696	0.304	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.696	0.304	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.696	0.304	0.000
G40 Epilepsy	0.696	0.304	0.000
B99-B99 Other infectious diseases	0.695	0.304	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.695	0.304	0.000
B65-B83 Helminthiases	0.695	0.304	0.000
B50-B64 Protozoal diseases	0.695	0.304	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.695	0.304	0.000
A75-A79 Rickettsioses	0.695	0.304	0.000
A70-A74 Other diseases caused by chlamydiae	0.695	0.304	0.000
A65-A69 Other spirochaetal diseases	0.695	0.304	0.000
A20-A28 Certain zoonotic bacterial diseases	0.695	0.304	0.000
A15-A19 Tuberculosis	0.695	0.304	0.000
Y40 Systemic antibiotics	0.695	0.305	0.000
G57.1 Meralgia paraesthetica	0.695	0.305	0.000
T92 Sequelae of injuries of upper limb	0.695	0.305	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.695	0.305	0.000
C51 Malignant neoplasm of vulva	0.694	0.306	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.694	0.306	0.000
D00-D09 In situ neoplasms	0.694	0.306	0.000
D37.4 Colon	0.694	0.306	0.000
X50-X57 Overexertion, travel and privation	0.694	0.306	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.692	0.308	0.000
M33 Dermatopolymyositis	0.692	0.308	0.000
M32 Systemic lupus erythematosus	0.692	0.308	0.000
M30 Polyarteritis nodosa and related conditions	0.692	0.308	0.000
S10-S19 Injuries to the neck	0.690	0.310	0.000
S02.4 Fracture of malar and maxillary bones	0.690	0.310	0.000
G90 Disorders of autonomic nervous system	0.690	0.310	0.000
D37.7 Other digestive organs	0.689	0.311	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.689	0.311	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.689	0.311	0.000
E84 Cystic fibrosis	0.688	0.312	0.000
E79 Disorders of purine and pyrimidine metabolism	0.688	0.312	0.000
E77 Disorders of glycoprotein metabolism	0.688	0.312	0.000
E76 Disorders of glycosaminoglycan metabolism	0.688	0.312	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.688	0.312	0.000
E74 Other disorders of carbohydrate metabolism	0.688	0.312	0.000
E73 Lactose intolerance	0.688	0.312	0.000
E72 Other disorders of amino-acid metabolism	0.688	0.312	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.688	0.312	0.000
E70 Disorders of aromatic amino-acid metabolism	0.688	0.312	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.688	0.312	0.000
W07 Fall involving chair	0.688	0.312	0.000
O16 Unspecified maternal hypertension	0.687	0.313	0.000
G52 Disorders of other cranial nerves	0.685	0.315	0.000
S02.3 Fracture of orbital floor	0.684	0.316	0.000
C77.8 Lymph nodes of multiple regions	0.684	0.316	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.684	0.316	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.684	0.316	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.682	0.317	0.000
E11.2 With renal complications	0.000	0.318	0.681
M20.3 Other deformity of hallux (acquired)	0.681	0.319	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.681	0.319	0.000
M65.3 Trigger finger	0.679	0.321	0.000
E87.4 Mixed disorder of acid-base balance	0.679	0.321	0.000
Y00-Y09 Assault	0.678	0.322	0.000
C12 Malignant neoplasm of pyriform sinus	0.677	0.323	0.000
M00-M03 Infectious arthropathies	0.676	0.324	0.000
M86-M90 Other osteopathies	0.676	0.324	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.673	0.327	0.000
Q51 Congenital malformations of uterus and cervix	0.672	0.328	0.000
M25.72 Osteophyte (Upper arm)	0.671	0.329	0.000
S80-S89 Injuries to the knee and lower leg	0.671	0.329	0.000
T58 Toxic effect of carbon monoxide	0.671	0.329	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.669	0.331	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.669	0.331	0.000
M40-M43 Deforming dorsopathies	0.669	0.331	0.000
B35 Dermatophytosis	0.668	0.331	0.000
M25.71 Osteophyte (Shoulder region)	0.668	0.332	0.000
M22 Disorders of patella	0.668	0.332	0.000
C53 Malignant neoplasm of cervix uteri	0.667	0.333	0.000
S02.5 Fracture of tooth	0.667	0.333	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.667	0.333	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.667	0.333	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.666	0.334	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.666	0.334	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.665	0.335	0.000
Y35-Y36 Legal intervention and operations of war	0.665	0.335	0.000
Y10-Y34 Event of undetermined intent	0.665	0.335	0.000
X85-X99 Assault	0.665	0.335	0.000
X30-X39 Exposure to forces of nature	0.665	0.335	0.000
X10-X19 Contact with heat and hot substances	0.665	0.335	0.000
X00-X09 Exposure to smoke, fire and flames	0.665	0.335	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.665	0.335	0.000
W75-W84 Other accidental threats to breathing	0.665	0.335	0.000
W65-W74 Accidental drowning and submersion	0.665	0.335	0.000
V98-V99 Other and unspecified transport accidents	0.665	0.335	0.000
V95-V97 Air and space transport accidents	0.665	0.335	0.000
V90-V94 Water transport accidents	0.665	0.335	0.000
V70-V79 Bus occupant injured in transport accident	0.665	0.335	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.665	0.335	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.665	0.335	0.000
V40-V49 Car occupant injured in transport accident	0.665	0.335	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.665	0.335	0.000
V01-V09 Pedestrian injured in transport accident	0.665	0.335	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.665	0.335	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.664	0.336	0.000
F99-F99 Unspecified mental disorder	0.664	0.336	0.000
S91 Open wound of ankle and foot	0.663	0.337	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.663	0.337	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.663	0.337	0.000
C31 Malignant neoplasm of accessory sinuses	0.663	0.337	0.000
C37 Malignant neoplasm of thymus	0.663	0.337	0.000
C33 Malignant neoplasm of trachea	0.663	0.337	0.000
D37.9 Digestive organ, unspecified	0.662	0.338	0.000
D37.3 Appendix	0.662	0.338	0.000
F80-F89 Disorders of psychological development	0.662	0.338	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.661	0.338	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.661	0.339	0.000
C04 Malignant neoplasm of floor of mouth	0.661	0.339	0.000
M66 Spontaneous rupture of synovium and tendon	0.660	0.339	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.659	0.340	0.000
Q64 Other congenital malformations of urinary system	0.659	0.341	0.000
S02.7 Multiple fractures involving skull and facial bones	0.659	0.341	0.000
E27.1 Primary adrenocortical insufficiency	0.659	0.341	0.000
M24.6 Ankylosis of joint	0.659	0.341	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.658	0.342	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.658	0.342	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.658	0.342	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.658	0.342	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.658	0.342	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.658	0.342	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.658	0.342	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.657	0.342	0.000
D37.0 Lip, oral cavity and pharynx	0.657	0.343	0.000
D37.6 Liver, gallbladder and bile ducts	0.657	0.343	0.000
W05.0 Home	0.656	0.344	0.000
M25.56 Pain in joint (Lower leg)	0.656	0.344	0.000
G51.0 Bell's palsy	0.656	0.344	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.654	0.346	0.000
G57.5 Tarsal tunnel syndrome	0.654	0.346	0.000
G57.4 Lesion of medial popliteal nerve	0.654	0.346	0.000
G57.3 Lesion of lateral popliteal nerve	0.654	0.346	0.000
G57.2 Lesion of femoral nerve	0.654	0.346	0.000
G57.0 Lesion of sciatic nerve	0.654	0.346	0.000
B00 Herpesviral [herpes simplex] infections	0.654	0.346	0.000
B91 Sequelae of poliomyelitis	0.653	0.347	0.000
D48.0 Bone and articular cartilage	0.653	0.347	0.000
G82.5 Tetraplegia, unspecified	0.653	0.347	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.652	0.347	0.000
X20-X29 Contact with venomous animals and plants	0.651	0.349	0.000
B37 Candidiasis	0.651	0.349	0.000
T98 Sequelae of other and unspecified effects of external causes	0.651	0.349	0.000
S01.9 Open wound of head, part unspecified	0.651	0.349	0.000
D48.5 Skin	0.651	0.349	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.650	0.349	0.000
S32.4 Fracture of acetabulum	0.650	0.350	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.650	0.350	0.000
C95 Leukaemia of unspecified cell type	0.650	0.350	0.000
C94 Other leukaemias of specified cell type	0.650	0.350	0.000
C93 Monocytic leukaemia	0.650	0.350	0.000
C86 Other specified types of T/NK-cell lymphoma	0.650	0.350	0.000
E88 Other metabolic disorders	0.649	0.350	0.000
M24.0 Loose body in joint	0.649	0.351	0.000
M25.9 Joint disorder, unspecified	0.649	0.351	0.000
M25.2 Flail joint	0.649	0.351	0.000
M25.1 Fistula of joint	0.649	0.351	0.000
D47.2 Monoclonal gammopathy	0.649	0.351	0.000
S02.0 Fracture of vault of skull	0.648	0.352	0.000
M25.76 Osteophyte (Lower leg)	0.648	0.352	0.000
M31 Other necrotising vasculopathies	0.647	0.352	0.000
C88 Malignant immunoproliferative diseases	0.647	0.353	0.000
S40-S49 Injuries to the shoulder and upper arm	0.647	0.353	0.000
C91 Lymphoid leukaemia	0.647	0.353	0.000
W20-W49 Exposure to inanimate mechanical forces	0.647	0.353	0.000
M24.2 Disorder of ligament	0.646	0.353	0.000
M70-M79 Other soft tissue disorders	0.646	0.354	0.000
W17.6 Industrial and construction area	0.646	0.354	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.645	0.355	0.000
S37 Injury of urinary and pelvic organs	0.645	0.355	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.645	0.355	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.645	0.355	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.645	0.355	0.000
E65-E68 Obesity and other hyperalimentation	0.644	0.355	0.002
S00.2 Other superficial injuries of eyelid and periocular area	0.644	0.356	0.000
S05.1 Contusion of eyeball and orbital tissues	0.644	0.356	0.000
C07 Malignant neoplasm of parotid gland	0.643	0.356	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.643	0.357	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.643	0.357	0.000
T46.7 Peripheral vasodilators	0.643	0.357	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.643	0.357	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.643	0.357	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.643	0.357	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.643	0.357	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.643	0.357	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.643	0.357	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.642	0.358	0.000
A48 Other bacterial diseases, not elsewhere classified	0.642	0.358	0.000
A44 Bartonellosis	0.642	0.358	0.000
A43 Nocardiosis	0.642	0.358	0.000
A42 Actinomycosis	0.642	0.358	0.000
A39 Meningococcal infection	0.642	0.358	0.000
A37 Whooping cough	0.642	0.358	0.000
A36 Diphtheria	0.642	0.358	0.000
A32 Listeriosis	0.642	0.358	0.000
A31 Infection due to other mycobacteria	0.642	0.358	0.000
A30 Leprosy [Hansen's disease]	0.642	0.358	0.000
A38 Scarlet fever	0.642	0.358	0.000
A35 Other tetanus	0.642	0.358	0.000
A34 Obstetrical tetanus	0.642	0.358	0.000
A33 Tetanus neonatorum	0.642	0.358	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.639	0.359	0.002
M34 Systemic sclerosis	0.641	0.359	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.641	0.359	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.640	0.360	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.639	0.361	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.638	0.362	0.000
W18 Other fall on same level	0.638	0.362	0.000
O14.9 Preeclampsia, unspecified	0.637	0.363	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.637	0.363	0.000
S06 Intracranial injury	0.636	0.363	0.000
E13 Other specified diabetes mellitus	0.030	0.364	0.606
E12 Malnutrition-related diabetes mellitus	0.030	0.364	0.606
T66-T78 Other and unspecified effects of external causes	0.636	0.364	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.636	0.364	0.000
M51 Other intervertebral disk disorders	0.636	0.364	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.635	0.365	0.000
Q53 Undescended testicle	0.635	0.365	0.000
S70-S79 Injuries to the hip and thigh	0.635	0.365	0.000
B02 Zoster [herpes zoster]	0.635	0.365	0.000
V80-V89 Other land transport accidents	0.635	0.365	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.634	0.366	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.634	0.366	0.000
S09 Other and unspecified injuries of head	0.634	0.366	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.633	0.367	0.000
M47 Spondylosis	0.632	0.368	0.000
M25.52 Pain in joint (Upper arm)	0.631	0.369	0.000
F33 Recurrent depressive disorder	0.631	0.369	0.000
W17.5 Trade and service area	0.631	0.369	0.000
B34 Viral infection of unspecified site	0.631	0.369	0.000
Q05 Spina bifida	0.630	0.370	0.000
Y40.9 Systemic antibiotic, unspecified	0.630	0.370	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.630	0.370	0.000
T59 Toxic effect of other gases, fumes and vapours	0.630	0.370	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.629	0.370	0.000
E14 Unspecified diabetes mellitus	0.017	0.371	0.612
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.629	0.371	0.000
C92.0 Acute myeloid leukaemia	0.629	0.371	0.000
O85-O92 Complications predominantly related to the puerperium	0.628	0.372	0.000
V20-V29 Motorcycle rider injured in transport accident	0.628	0.372	0.000
M24.5 Contracture of joint	0.628	0.372	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.628	0.372	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.627	0.373	0.000
Q54.9 Hypospadias, unspecified	0.627	0.373	0.000
S92 Fracture of foot, except ankle	0.627	0.373	0.000
M25.74 Osteophyte (Hand)	0.626	0.374	0.000
M25.0 Haemarthrosis	0.626	0.374	0.000
T63 Toxic effect of contact with venomous animals	0.626	0.374	0.000
E11.0 With coma	0.001	0.374	0.625
S02.8 Fractures of other skull and facial bones	0.626	0.374	0.000
C80.9 Malignant neoplasm, unspecified	0.626	0.374	0.000
E34 Other endocrine disorders	0.624	0.375	0.001
Q43 Other congenital malformations of intestine	0.625	0.375	0.000
A80-A89 Viral infections of the central nervous system	0.624	0.375	0.000
D47.1 Chronic myeloproliferative disease	0.624	0.376	0.000
M99 Biomechanical lesions, not elsewhere classified	0.623	0.377	0.000
S00.5 Superficial injury of lip and oral cavity	0.622	0.378	0.000
S00.4 Superficial injury of ear	0.622	0.378	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.621	0.378	0.000
G44 Other headache syndromes	0.621	0.379	0.000
C81 Hodgkin's disease	0.621	0.379	0.000
Q61.0 Congenital single renal cyst	0.621	0.379	0.000
M65.8 Other synovitis and tenosynovitis	0.621	0.379	0.000
O00-O08 Pregnancy with abortive outcome	0.621	0.379	0.000
T42.1 Iminostilbenes	0.620	0.379	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.620	0.380	0.000
T51.9 Alcohol, unspecified	0.620	0.380	0.000
S02.2 Fracture of nasal bones	0.620	0.380	0.000
B18 Chronic viral hepatitis	0.619	0.381	0.000
T65 Toxic effect of other and unspecified substances	0.619	0.381	0.000
T62 Toxic effect of other noxious substances eaten as food	0.619	0.381	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.619	0.381	0.000
T60 Toxic effect of pesticides	0.619	0.381	0.000
T57 Toxic effect of other inorganic substances	0.619	0.381	0.000
T56 Toxic effect of metals	0.619	0.381	0.000
T54 Toxic effect of corrosive substances	0.619	0.381	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.619	0.381	0.000
T52 Toxic effect of organic solvents	0.619	0.381	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.619	0.381	0.000
T55 Toxic effect of soaps and detergents	0.619	0.381	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.619	0.381	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.618	0.382	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations