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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2237897
log Bayes Factor = 14.807
Chromosome 11   position 2,858,546  (GRCh37) Explore rs2237897 on Ensembl!
Variant rs2237897 is listed in the   GWAS Catalog   ⇪
Variant rs2237897 is part of Cluster X0076

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.990 0.010 0.000
M25 Other joint disorders, not elsewhere classified
0.989 0.011 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.987 0.013 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.985 0.015 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.985 0.015 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.984 0.016 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.982 0.018 0.000
C79 Secondary malignant neoplasm of other sites
0.975 0.025 0.000
E11 Non-insulin-dependent diabetes mellitus
0.001 0.030 0.970
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.969 0.031 0.000
M25.7 Osteophyte
0.965 0.035 0.000
C77.2 Intra-abdominal lymph nodes
0.964 0.036 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.958 0.042 0.000
G57 Mononeuropathies of lower limb
0.954 0.046 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.948 0.052 0.000
A30-A49 Other bacterial diseases
0.944 0.056 0.000
Chapter XX External causes of morbidity and mortality
0.936 0.064 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.936 0.064 0.000
G40-G47 Episodic and paroxysmal disorders
0.931 0.069 0.000
G90-G99 Other disorders of the nervous system
0.930 0.070 0.000
E11.3 With ophthalmic complications
0.000 0.072 0.927
M24 Other specific joint derangements
0.917 0.083 0.000
Chapter V Mental and behavioural disorders
0.915 0.085 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.910 0.090 0.000
C92 Myeloid leukaemia
0.910 0.090 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.907 0.093 0.000
A41 Other septicaemia
0.904 0.096 0.000
G57.8 Other mononeuropathies of lower limb
0.904 0.096 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.894 0.106 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.892 0.108 0.000
M25.8 Other specified joint disorders
0.890 0.110 0.000
C51-C58 Malignant neoplasms of female genital organs
0.889 0.111 0.000
G50 Disorders of trigeminal nerve
0.888 0.112 0.000
Q60-Q64 Congenital malformations of the urinary system
0.888 0.112 0.000
M65-M68 Disorders of synovium and tendon
0.888 0.112 0.000
C77.1 Intrathoracic lymph nodes
0.888 0.112 0.000
S00-S09 Injuries to the head
0.888 0.112 0.000
M20 Acquired deformities of fingers and toes
0.886 0.114 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.880 0.120 0.000
G40 Epilepsy
0.876 0.124 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.875 0.125 0.000
M20.4 Other hammer toe(s) (acquired)
0.875 0.125 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.873 0.127 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.872 0.128 0.000
M25.5 Pain in joint
0.870 0.130 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.870 0.130 0.000
A41.9 Septicaemia, unspecified
0.870 0.130 0.000
M25.78 Osteophyte (Other)
0.870 0.130 0.000
O16 Unspecified maternal hypertension
0.867 0.133 0.000
E10-E14 Diabetes mellitus
0.032 0.138 0.831
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.853 0.147 0.000
C80 Malignant neoplasm without specification of site
0.850 0.150 0.000
C92.1 Chronic myeloid leukaemia
0.849 0.151 0.000
M21 Other acquired deformities of limbs
0.845 0.155 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.843 0.157 0.000
G57.6 Lesion of plantar nerve
0.841 0.159 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.841 0.159 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.838 0.162 0.000
G03 Meningitis due to other and unspecified causes
0.838 0.162 0.000
M25.57 Pain in joint (Ankle and foot)
0.837 0.163 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.835 0.165 0.000
T92 Sequelae of injuries of upper limb
0.832 0.168 0.000
S90-S99 Injuries to the ankle and foot
0.829 0.171 0.000
C77.0 Lymph nodes of head, face and neck
0.828 0.172 0.000
D37.2 Small intestine
0.823 0.177 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.822 0.178 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.821 0.179 0.000
M65 Synovitis and tenosynovitis
0.820 0.180 0.000
G50.0 Trigeminal neuralgia
0.820 0.180 0.000
E11.4 With neurological complications
0.000 0.182 0.817
C34 Malignant neoplasm of bronchus and lung
0.816 0.183 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.816 0.184 0.000
G91 Hydrocephalus
0.811 0.189 0.000
D46 Myelodysplastic syndromes
0.811 0.189 0.000
T46.1 Calcium-channel blockers
0.811 0.189 0.000
C77.9 Lymph node, unspecified
0.810 0.190 0.000
D45 Polycythaemia vera
0.809 0.190 0.000
Q61 Cystic kidney disease
0.809 0.191 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.807 0.193 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.807 0.193 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.806 0.194 0.000
D37.5 Rectum
0.806 0.194 0.000
M25.76 Osteophyte (Lower leg)
0.806 0.194 0.000
S02 Fracture of skull and facial bones
0.804 0.196 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.804 0.196 0.000
Q50-Q56 Congenital malformations of genital organs
0.803 0.197 0.000
G44 Other headache syndromes
0.803 0.197 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.802 0.197 0.000
Y40 Systemic antibiotics
0.802 0.198 0.000
G58 Other mononeuropathies
0.800 0.200 0.000
M25.71 Osteophyte (Shoulder region)
0.800 0.200 0.000
T93 Sequelae of injuries of lower limb
0.799 0.201 0.000
T91 Sequelae of injuries of neck and trunk
0.799 0.201 0.000
F30-F39 Mood [affective] disorders
0.799 0.201 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.798 0.202 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.795 0.205 0.000
G96 Other disorders of central nervous system
0.795 0.205 0.000
D00-D09 In situ neoplasms
0.794 0.206 0.000
T79-T79 Certain early complications of trauma
0.793 0.207 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.793 0.207 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.766 0.209 0.025
Q80-Q89 Other congenital malformations
0.790 0.210 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.790 0.210 0.000
A40 Streptococcal septicaemia
0.789 0.211 0.000
G51 Facial nerve disorders
0.786 0.214 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.783 0.217 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.783 0.217 0.000
Q00-Q07 Congenital malformations of the nervous system
0.783 0.217 0.000
S80-S89 Injuries to the knee and lower leg
0.782 0.218 0.000
S50-S59 Injuries to the elbow and forearm
0.779 0.220 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.778 0.222 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.776 0.224 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.772 0.228 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.772 0.228 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.772 0.228 0.000
M25.74 Osteophyte (Hand)
0.771 0.229 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.771 0.229 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.770 0.230 0.000
M25.9 Joint disorder, unspecified
0.769 0.231 0.000
F60-F69 Disorders of adult personality and behaviour
0.769 0.231 0.000
C56 Malignant neoplasm of ovary
0.768 0.232 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.768 0.232 0.000
G03.9 Meningitis, unspecified
0.767 0.233 0.000
M60-M63 Disorders of muscles
0.767 0.233 0.000
D37.4 Colon
0.767 0.233 0.000
Chapter X Diseases of the respiratory system
0.764 0.236 0.000
D37.1 Stomach
0.763 0.236 0.000
C34.9 Bronchus or lung, unspecified
0.762 0.238 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.761 0.239 0.000
B35-B49 Mycoses
0.761 0.239 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.761 0.239 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.760 0.240 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.759 0.241 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.758 0.242 0.000
W00-W19 Falls
0.757 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.244 0.000
D47.2 Monoclonal gammopathy
0.753 0.247 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.752 0.248 0.000
G90 Disorders of autonomic nervous system
0.750 0.250 0.000
G47 Sleep disorders
0.749 0.251 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.748 0.252 0.000
B15-B19 Viral hepatitis
0.748 0.252 0.000
O85-O92 Complications predominantly related to the puerperium
0.747 0.253 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.746 0.254 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.746 0.254 0.000
O80-O84 Delivery
0.745 0.255 0.000
Chapter XXII Codes for special purposes
0.745 0.255 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.745 0.255 0.000
C79.6 Secondary malignant neoplasm of ovary
0.744 0.255 0.000
C91 Lymphoid leukaemia
0.743 0.257 0.000
G00 Bacterial meningitis, not elsewhere classified
0.743 0.257 0.000
E10 Insulin-dependent diabetes mellitus
0.011 0.257 0.731
M25.72 Osteophyte (Upper arm)
0.741 0.259 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.740 0.260 0.000
E70-E90 Metabolic disorders
0.738 0.260 0.001
O14.9 Preeclampsia, unspecified
0.739 0.261 0.000
C88 Malignant immunoproliferative diseases
0.738 0.261 0.000
T98 Sequelae of other and unspecified effects of external causes
0.738 0.262 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.737 0.263 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.737 0.263 0.000
M24.0 Loose body in joint
0.736 0.264 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.735 0.265 0.000
Y43 Primarily systemic agents
0.735 0.265 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.735 0.265 0.000
A46 Erysipelas
0.734 0.266 0.000
C77.8 Lymph nodes of multiple regions
0.732 0.267 0.000
W50-W64 Exposure to animate mechanical forces
0.732 0.268 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.732 0.268 0.000
Y40.9 Systemic antibiotic, unspecified
0.732 0.268 0.000
C77.5 Intrapelvic lymph nodes
0.731 0.268 0.000
M91-M94 Chondropathies
0.731 0.269 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.731 0.269 0.000
C80.9 Malignant neoplasm, unspecified
0.730 0.270 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.729 0.271 0.000
E86 Volume depletion
0.729 0.271 0.000
O00-O08 Pregnancy with abortive outcome
0.729 0.271 0.000
S70-S79 Injuries to the hip and thigh
0.727 0.273 0.000
M24.6 Ankylosis of joint
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
M45-M49 Spondylopathies
0.726 0.274 0.000
T90 Sequelae of injuries of head
0.726 0.274 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.726 0.274 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.722 0.278 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.721 0.279 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.721 0.279 0.000
M34 Systemic sclerosis
0.720 0.280 0.000
G82 Paraplegia and tetraplegia
0.720 0.280 0.000
S10-S19 Injuries to the neck
0.720 0.280 0.000
C53 Malignant neoplasm of cervix uteri
0.719 0.281 0.000
S05 Injury of eye and orbit
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.286 0.000
M33 Dermatopolymyositis
0.714 0.286 0.000
M32 Systemic lupus erythematosus
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.712 0.288 0.000
M25.84 Other specified joint disorders (Hand)
0.711 0.288 0.000
X50-X57 Overexertion, travel and privation
0.711 0.288 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
G44.2 Tension-type headache
0.711 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
C51 Malignant neoplasm of vulva
0.710 0.290 0.000
E14 Unspecified diabetes mellitus
0.011 0.290 0.699
M25.2 Flail joint
0.709 0.291 0.000
M25.1 Fistula of joint
0.709 0.291 0.000
M25.53 Pain in joint (Forearm)
0.709 0.291 0.000
M20.0 Deformity of finger(s)
0.708 0.292 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.708 0.292 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.708 0.292 0.000
S00 Superficial injury of head
0.708 0.292 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.707 0.293 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.707 0.293 0.000
T39.0 Salicylates
0.707 0.293 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.706 0.294 0.000
C95 Leukaemia of unspecified cell type
0.706 0.294 0.000
C94 Other leukaemias of specified cell type
0.706 0.294 0.000
C93 Monocytic leukaemia
0.706 0.294 0.000
C86 Other specified types of T/NK-cell lymphoma
0.706 0.294 0.000
G52 Disorders of other cranial nerves
0.705 0.294 0.000
Q64 Other congenital malformations of urinary system
0.705 0.295 0.000
C77.4 Inguinal and lower limb lymph nodes
0.705 0.295 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.704 0.296 0.000
Q35-Q37 Cleft lip and cleft palate
0.704 0.296 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.704 0.296 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.704 0.296 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.703 0.297 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.703 0.297 0.000
F99-F99 Unspecified mental disorder
0.703 0.297 0.000
C90.0 Multiple myeloma
0.702 0.298 0.000
T42.1 Iminostilbenes
0.702 0.298 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.702 0.298 0.000
Q61.0 Congenital single renal cyst
0.701 0.299 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.700 0.300 0.000
M70-M79 Other soft tissue disorders
0.700 0.300 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.699 0.301 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.699 0.301 0.000
E11.6 With other specified complications
0.001 0.301 0.698
M25.0 Haemarthrosis
0.698 0.302 0.000
G96.0 Cerebrospinal fluid leak
0.698 0.302 0.000
D37.7 Other digestive organs
0.698 0.302 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.697 0.303 0.000
E10.9 Without complications
0.001 0.303 0.696
D70-D77 Other diseases of blood and blood-forming organs
0.697 0.303 0.000
E11.8 With unspecified complications
0.001 0.304 0.695
E11.7 With multiple complications
0.001 0.304 0.695
B99-B99 Other infectious diseases
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
O15 Eclampsia
0.695 0.305 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.695 0.305 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.695 0.305 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
M24.1 Other articular cartilage disorders
0.693 0.307 0.000
S02.6 Fracture of mandible
0.693 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.308 0.000
D37.6 Liver, gallbladder and bile ducts
0.692 0.308 0.000
M25.79 Osteophyte (Site unspecified)
0.692 0.308 0.000
M25.73 Osteophyte (Forearm)
0.692 0.308 0.000
M25.70 Osteophyte (Multiple sites)
0.692 0.308 0.000
D47.1 Chronic myeloproliferative disease
0.691 0.308 0.000
M50-M54 Other dorsopathies
0.689 0.311 0.000
Y48 Anaesthetics and therapeutic gases
0.689 0.311 0.000
S40-S49 Injuries to the shoulder and upper arm
0.687 0.313 0.000
T95 Sequelae of burns, corrosions and frostbite
0.686 0.313 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.686 0.313 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.686 0.313 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.686 0.313 0.000
S56 Injury of muscle and tendon at forearm level
0.686 0.314 0.000
S02.1 Fracture of base of skull
0.685 0.315 0.000
M31 Other necrotising vasculopathies
0.685 0.315 0.000
M24.2 Disorder of ligament
0.685 0.315 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.685 0.315 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.685 0.315 0.000
M00-M03 Infectious arthropathies
0.685 0.315 0.000
D04 Carcinoma in situ of skin
0.685 0.315 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.684 0.316 0.000
G57.5 Tarsal tunnel syndrome
0.684 0.316 0.000
G57.4 Lesion of medial popliteal nerve
0.684 0.316 0.000
G57.3 Lesion of lateral popliteal nerve
0.684 0.316 0.000
G57.2 Lesion of femoral nerve
0.684 0.316 0.000
G57.1 Meralgia paraesthetica
0.684 0.316 0.000
G57.0 Lesion of sciatic nerve
0.684 0.316 0.000
Y45.0 Opioids and related analgesics
0.684 0.316 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.683 0.317 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
Chapter VIII Diseases of the ear and mastoid process
0.683 0.317 0.000
V40-V49 Car occupant injured in transport accident
0.682 0.318 0.000
S91 Open wound of ankle and foot
0.682 0.318 0.000
D37.9 Digestive organ, unspecified
0.680 0.320 0.000
D37.3 Appendix
0.680 0.320 0.000
C92.0 Acute myeloid leukaemia
0.679 0.321 0.000
A00-A09 Intestinal infectious diseases
0.678 0.322 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.678 0.322 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.678 0.322 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.677 0.322 0.000
C34.0 Main bronchus
0.677 0.323 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.677 0.323 0.000
A49 Bacterial infection of unspecified site
0.677 0.323 0.000
A48 Other bacterial diseases, not elsewhere classified
0.677 0.323 0.000
A44 Bartonellosis
0.677 0.323 0.000
A43 Nocardiosis
0.677 0.323 0.000
A42 Actinomycosis
0.677 0.323 0.000
A39 Meningococcal infection
0.677 0.323 0.000
A37 Whooping cough
0.677 0.323 0.000
A36 Diphtheria
0.677 0.323 0.000
A32 Listeriosis
0.677 0.323 0.000
A31 Infection due to other mycobacteria
0.677 0.323 0.000
A30 Leprosy [Hansen's disease]
0.677 0.323 0.000
A38 Scarlet fever
0.677 0.323 0.000
A35 Other tetanus
0.677 0.323 0.000
A34 Obstetrical tetanus
0.677 0.323 0.000
A33 Tetanus neonatorum
0.677 0.323 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.676 0.324 0.000
A41.8 Other specified septicaemia
0.675 0.325 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.675 0.325 0.000
M25.52 Pain in joint (Upper arm)
0.674 0.326 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.674 0.326 0.000
C79.2 Secondary malignant neoplasm of skin
0.673 0.326 0.000
D37.0 Lip, oral cavity and pharynx
0.673 0.327 0.000
B25-B34 Other viral diseases
0.673 0.327 0.000
F32 Depressive episode
0.673 0.327 0.000
M65.3 Trigger finger
0.671 0.329 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.671 0.329 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.671 0.329 0.000
Y35-Y36 Legal intervention and operations of war
0.671 0.329 0.000
Y10-Y34 Event of undetermined intent
0.671 0.329 0.000
X85-X99 Assault
0.671 0.329 0.000
X30-X39 Exposure to forces of nature
0.671 0.329 0.000
X10-X19 Contact with heat and hot substances
0.671 0.329 0.000
X00-X09 Exposure to smoke, fire and flames
0.671 0.329 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.671 0.329 0.000
W75-W84 Other accidental threats to breathing
0.671 0.329 0.000
W65-W74 Accidental drowning and submersion
0.671 0.329 0.000
V98-V99 Other and unspecified transport accidents
0.671 0.329 0.000
V95-V97 Air and space transport accidents
0.671 0.329 0.000
V90-V94 Water transport accidents
0.671 0.329 0.000
V70-V79 Bus occupant injured in transport accident
0.671 0.329 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.671 0.329 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.671 0.329 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.671 0.329 0.000
V01-V09 Pedestrian injured in transport accident
0.671 0.329 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.671 0.329 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.671 0.329 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.671 0.329 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.671 0.329 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.671 0.329 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.671 0.329 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.671 0.329 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.671 0.329 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.670 0.329 0.000
M21.0 Valgus deformity, not elsewhere classified
0.670 0.330 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.669 0.331 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.669 0.331 0.000
M21.3 Wrist or foot drop (acquired)
0.668 0.332 0.000
G43 Migraine
0.668 0.332 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.667 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.667 0.333 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.667 0.333 0.000
G92 Toxic encephalopathy
0.667 0.333 0.000
G91.8 Other hydrocephalus
0.666 0.334 0.000
M22 Disorders of patella
0.666 0.334 0.000
E11.0 With coma
0.001 0.335 0.665
C90.2 Plasmacytoma, extramedullary
0.665 0.335 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.665 0.335 0.000
C32 Malignant neoplasm of larynx
0.665 0.335 0.000
F60 Specific personality disorders
0.664 0.336 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.664 0.336 0.000
J90-J94 Other diseases of pleura
0.664 0.336 0.000
T42.4 Benzodiazepines
0.663 0.337 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.663 0.337 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.663 0.337 0.000
Q61.2 Polycystic kidney, adult type
0.662 0.338 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
D48.5 Skin
0.662 0.338 0.000
C81 Hodgkin's disease
0.661 0.339 0.000
G20-G26 Extrapyramidal and movement disorders
0.660 0.340 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.660 0.340 0.000
D70 Agranulocytosis
0.659 0.341 0.000
M24.5 Contracture of joint
0.659 0.341 0.000
Y45.2 Propionic acid derivatives
0.659 0.341 0.000
G91.9 Hydrocephalus, unspecified
0.658 0.342 0.000
M25.56 Pain in joint (Lower leg)
0.658 0.342 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.658 0.342 0.000
M24.9 Joint derangement, unspecified
0.657 0.343 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.657 0.343 0.000
M24.7 Protrusio acetabuli
0.657 0.343 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.657 0.343 0.000
B00 Herpesviral [herpes simplex] infections
0.656 0.344 0.000
O60-O75 Complications of labour and delivery
0.656 0.344 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.656 0.344 0.000
F70-F79 Mental retardation
0.656 0.344 0.000
S92 Fracture of foot, except ankle
0.655 0.345 0.000
M80-M85 Disorders of bone density and structure
0.655 0.345 0.000
J09-J18 Influenza and pneumonia
0.655 0.345 0.000
G54 Nerve root and plexus disorders
0.655 0.345 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.655 0.345 0.000
M66 Spontaneous rupture of synovium and tendon
0.654 0.345 0.000
M86-M90 Other osteopathies
0.654 0.346 0.000
T66-T78 Other and unspecified effects of external causes
0.653 0.347 0.000
F80-F89 Disorders of psychological development
0.653 0.347 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.653 0.347 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.653 0.347 0.000
T46.7 Peripheral vasodilators
0.653 0.347 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.653 0.347 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.653 0.347 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.653 0.347 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.653 0.347 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.653 0.347 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.653 0.347 0.000
C92.9 Myeloid leukaemia, unspecified
0.652 0.348 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.652 0.348 0.000
C92.7 Other myeloid leukaemia
0.652 0.348 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.652 0.348 0.000
C92.5 Acute myelomonocytic leukaemia
0.652 0.348 0.000
C92.4 Acute promyelocytic leukaemia
0.652 0.348 0.000
C92.3 Myeloid sarcoma
0.652 0.348 0.000
C92.2 Subacute myeloid leukaemia
0.652 0.348 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.652 0.348 0.000
V80-V89 Other land transport accidents
0.651 0.349 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.650 0.350 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.650 0.350 0.000
C31 Malignant neoplasm of accessory sinuses
0.650 0.350 0.000
C37 Malignant neoplasm of thymus
0.650 0.350 0.000
C33 Malignant neoplasm of trachea
0.650 0.350 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.650 0.350 0.000
J30-J39 Other diseases of upper respiratory tract
0.649 0.351 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.649 0.351 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.649 0.351 0.000
A41.4 Septicaemia due to anaerobes
0.648 0.351 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.648 0.351 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.647 0.353 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.647 0.353 0.000
A80-A89 Viral infections of the central nervous system
0.647 0.353 0.000
G41 Status epilepticus
0.646 0.353 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.646 0.354 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.645 0.355 0.000
C84.4 Peripheral T-cell lymphoma
0.645 0.355 0.000
C85.1 B-cell lymphoma, unspecified
0.643 0.357 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.642 0.358 0.000
S86 Injury of muscle and tendon at lower leg level
0.642 0.358 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.642 0.358 0.000
Q05 Spina bifida
0.640 0.360 0.000
S00.1 Contusion of eyelid and periocular area
0.640 0.360 0.000
E11.1 With ketoacidosis
0.001 0.361 0.638
M25.89 Other specified joint disorders (Site unspecified)
0.638 0.362 0.000
M25.88 Other specified joint disorders (Other)
0.638 0.362 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.638 0.362 0.000
M25.83 Other specified joint disorders (Forearm)
0.638 0.362 0.000
M25.82 Other specified joint disorders (Upper arm)
0.638 0.362 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.638 0.362 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.638 0.362 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.637 0.362 0.000
C58 Malignant neoplasm of placenta
0.637 0.362 0.000
C52 Malignant neoplasm of vagina
0.637 0.362 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.637 0.363 0.000
G50.8 Other disorders of trigeminal nerve
0.637 0.363 0.000
G50.1 Atypical facial pain
0.637 0.363 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.637 0.363 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.637 0.363 0.000
J95-J99 Other diseases of the respiratory system
0.637 0.363 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.636 0.363 0.000
S08 Traumatic amputation of part of head
0.636 0.364 0.000
S07 Crushing injury of head
0.636 0.364 0.000
S04 Injury of cranial nerves
0.636 0.364 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.636 0.364 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.636 0.364 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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