TreeWAS – Variant ID: rs224329

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.000	1.000
M17.9 Gonarthrosis, unspecified	0.000	0.000	1.000
M20.1 Hallux valgus (acquired)	0.000	0.000	1.000
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.000	1.000
M23 Internal derangement of knee	0.000	0.000	1.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.000	1.000
M17.1 Other primary gonarthrosis	0.000	0.001	0.999
M23.3 Other meniscus derangements	0.000	0.001	0.999
M20 Acquired deformities of fingers and toes	0.000	0.001	0.999
M20-M25 Other joint disorders	0.000	0.002	0.998
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.004	0.996
M20.5 Other deformities of toe(s) (acquired)	0.000	0.011	0.989
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.011	0.989
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.014	0.986
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.021	0.979
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.025	0.975
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.037	0.963
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.040	0.960
M17.0 Primary gonarthrosis, bilateral	0.000	0.044	0.956
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.063	0.937
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.082	0.918
M23.8 Other internal derangements of knee	0.000	0.086	0.914
R59.1 Generalised enlarged lymph nodes	0.911	0.089	0.000
M23.4 Loose body in knee	0.000	0.094	0.906
R59.0 Localised enlarged lymph nodes	0.904	0.096	0.000
R59 Enlarged lymph nodes	0.902	0.098	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.103	0.897
M24 Other specific joint derangements	0.000	0.105	0.895
M22 Disorders of patella	0.000	0.110	0.890
M24.1 Other articular cartilage disorders	0.000	0.132	0.868
M23.49 Loose body in knee-Unspec lig/men	0.000	0.132	0.868
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.157	0.843
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.158	0.842
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.158	0.842
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.174	0.826
M21 Other acquired deformities of limbs	0.000	0.176	0.824
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.189	0.811
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.195	0.805
M23.0 Cystic meniscus	0.000	0.196	0.804
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.200	0.800
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.206	0.794
M21.1 Varus deformity, not elsewhere classified	0.000	0.217	0.783
M23.46 Loose body in knee-O/unsp lat men	0.000	0.218	0.781
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.226	0.774
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.229	0.771
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.242	0.758
M17.5 Other secondary gonarthrosis	0.000	0.248	0.752
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.262	0.738
M22.2 Patellofemoral disorders	0.000	0.269	0.731
M22.0 Recurrent dislocation of patella	0.000	0.275	0.725
M24.6 Ankylosis of joint	0.000	0.277	0.723
M22.3 Other derangements of patella	0.000	0.278	0.722
M33 Dermatopolymyositis	0.000	0.283	0.717
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.283	0.717
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.283	0.717
M23.37 Other meniscus derangements-Capsular lig	0.000	0.284	0.716
M23.1 Discoid meniscus (congenital)	0.000	0.287	0.713
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.290	0.710
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.296	0.704
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.298	0.702
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.300	0.700
M20.0 Deformity of finger(s)	0.000	0.303	0.697
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.305	0.695
M21.4 Flat foot [pes planus] (acquired)	0.000	0.314	0.686
M20.3 Other deformity of hallux (acquired)	0.000	0.317	0.683
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.318	0.681
M23.40 Loose body in knee-Mult sites	0.000	0.337	0.663
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.339	0.661
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.342	0.658
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.345	0.655
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.345	0.655
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.345	0.655
M22.9 Disorder of patella, unspecified	0.000	0.346	0.654
M23.47 Loose body in knee-Capsular lig	0.000	0.350	0.650
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.350	0.650
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.350	0.650
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.355	0.645
M32 Systemic lupus erythematosus	0.000	0.360	0.640
M22.1 Recurrent subluxation of patella	0.000	0.362	0.638
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.364	0.636
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.367	0.633
M21.6 Other acquired deformities of ankle and foot	0.000	0.367	0.633
M24.9 Joint derangement, unspecified	0.000	0.370	0.630
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.372	0.628
M23.5 Chronic instability of knee	0.000	0.372	0.628
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.374	0.625
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.376	0.624
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.377	0.623
M24.18 Other articular cartilage disorders (Other)	0.000	0.377	0.623
M24.14 Other articular cartilage disorders (Hand)	0.000	0.377	0.623
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.377	0.623
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.377	0.623
M22.8 Other disorders of patella	0.000	0.378	0.622
R59.9 Enlarged lymph nodes, unspecified	0.617	0.383	0.000
M23.9 Internal derangement of knee, unspecified	0.000	0.383	0.616
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.387	0.613
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.391	0.609
M22.4 Chondromalacia patellae	0.000	0.393	0.607
M24.5 Contracture of joint	0.000	0.398	0.602
M24.7 Protrusio acetabuli	0.000	0.400	0.600
M21.9 Acquired deformity of limb, unspecified	0.000	0.404	0.596
M33.1 Other dermatomyositis	0.000	0.411	0.589
M24.66 Ankylosis of joint (Lower leg)	0.000	0.412	0.588
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.413	0.587
M23.07 Cystic meniscus-Capsular lig	0.000	0.423	0.577
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.423	0.577
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.423	0.577
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.423	0.577
M23.00 Cystic meniscus (Multiple sites)	0.000	0.423	0.577
M21.3 Wrist or foot drop (acquired)	0.000	0.426	0.574
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.426	0.573
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.430	0.570
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.435	0.565
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.439	0.561
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.439	0.561
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.439	0.561
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.439	0.561
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.439	0.561
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.439	0.561
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.439	0.561
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.440	0.560
M23.43 Loose body in knee-Med lig/oth men	0.000	0.444	0.556
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.445	0.555
M36.3 Arthropathy in other blood disorders	0.000	0.445	0.555
M36.2 Haemophilic arthropathy	0.000	0.445	0.555
M36.1 Arthropathy in neoplastic disease	0.000	0.445	0.555
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.445	0.555
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.447	0.553
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.447	0.553
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.459	0.541
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.464	0.535
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.466	0.534
M30 Polyarteritis nodosa and related conditions	0.000	0.469	0.531
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.470	0.529
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.471	0.529
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.471	0.529
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.471	0.529
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.471	0.529
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.471	0.529
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.471	0.529
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.471	0.529
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.471	0.529
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.471	0.529
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.471	0.528
M21.8 Other specified acquired deformities of limbs	0.000	0.479	0.520
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.482	0.518
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.482	0.518
M24.68 Ankylosis of joint (Other)	0.000	0.482	0.518
M24.63 Ankylosis of joint (Forearm)	0.000	0.482	0.518
M24.62 Ankylosis of joint (Upper arm)	0.000	0.482	0.518
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.482	0.518
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.482	0.518
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.483	0.517
M33.9 Dermatopolymyositis, unspecified	0.000	0.486	0.514
M33.0 Juvenile dermatomyositis	0.000	0.486	0.514
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.489	0.511
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.489	0.511
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.489	0.511
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.489	0.511
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.489	0.511
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.489	0.511
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.489	0.511
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.489	0.511
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.493	0.507
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.499	0.500
M24.64 Ankylosis of joint (Hand)	0.000	0.500	0.500
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.504	0.496
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.504	0.495
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.508	0.492
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.508	0.492
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.508	0.492
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.508	0.492
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.508	0.492
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.508	0.492
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.508	0.492
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.508	0.492
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.508	0.492
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.525	0.475
M24.56 Contracture of joint (Lower leg)	0.000	0.530	0.470
M32.8 Other forms of systemic lupus erythematosus	0.000	0.532	0.468
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.536	0.463
M34 Systemic sclerosis	0.000	0.537	0.462
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.539	0.461
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.541	0.459
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.541	0.459
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.542	0.457
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.544	0.456
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.546	0.454
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.546	0.454
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.546	0.454
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.546	0.454
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.546	0.454
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.546	0.454
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.546	0.454
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.546	0.454
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.546	0.454
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.546	0.454
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.546	0.454
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.546	0.454
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.546	0.454
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.546	0.454
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.546	0.454
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.546	0.454
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.546	0.454
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.546	0.454
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.548	0.452
M24.98 Joint derangement, unspecified (Other)	0.000	0.548	0.452
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.548	0.452
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.548	0.452
M24.94 Joint derangement, unspecified (Hand)	0.000	0.548	0.452
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.548	0.452
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.548	0.452
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.548	0.452
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.548	0.452
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.549	0.450
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.549	0.450
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.549	0.450
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.549	0.450
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.549	0.450
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.549	0.450
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.549	0.450
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.549	0.450
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.549	0.450
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.549	0.450
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.549	0.450
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.549	0.450
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.549	0.450
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.549	0.450
M21.0 Valgus deformity, not elsewhere classified	0.000	0.554	0.446
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.558	0.442
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.558	0.442
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.558	0.442
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.558	0.442
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.558	0.442
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.558	0.442
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.558	0.442
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.559	0.441
M24.52 Contracture of joint (Upper arm)	0.000	0.560	0.440
M24.57 Contracture of joint (Ankle and foot)	0.000	0.567	0.433
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.568	0.432
M24.59 Contracture of joint (Site unspecified)	0.000	0.568	0.431
M24.58 Contracture of joint (Other)	0.000	0.568	0.431
M24.53 Contracture of joint (Forearm)	0.000	0.568	0.431
M24.50 Contracture of joint (Multiple sites)	0.000	0.568	0.431
M24.79 Protrusio acetabuli-Site unspec	0.000	0.569	0.430
M24.78 Protrusio acetabuli-Other	0.000	0.569	0.430
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.569	0.430
M24.76 Protrusio acetabuli-Lower leg	0.000	0.569	0.430
M24.74 Protrusio acetabuli-Hand	0.000	0.569	0.430
M24.73 Protrusio acetabuli-Forearm	0.000	0.569	0.430
M24.72 Protrusio acetabuli-Upper arm	0.000	0.569	0.430
M24.71 Protrusio acetabuli-Shldr region	0.000	0.569	0.430
M24.70 Protrusio acetabuli-Mult sites	0.000	0.569	0.430
M23.41 Loose body in knee-Ant lig/hrn men	0.001	0.571	0.428
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.572	0.428
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.573	0.427
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.573	0.427
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.573	0.427
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.573	0.427
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.573	0.427
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.573	0.427
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.573	0.427
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.573	0.427
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.573	0.427
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.578	0.422
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.580	0.420
M20.4 Other hammer toe(s) (acquired)	0.000	0.584	0.416
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.588	0.412
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.588	0.412
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.588	0.412
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.588	0.412
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.588	0.412
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.588	0.412
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.588	0.412
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.588	0.412
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.588	0.412
M21.2 Flexion deformity	0.000	0.593	0.406
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.599	0.400
M33.2 Polymyositis	0.000	0.600	0.399
M24.51 Contracture of joint (Shoulder region)	0.000	0.604	0.395
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.605	0.395
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.609	0.391
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.611	0.389
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.614	0.385
M21.7 Unequal limb length (acquired)	0.001	0.615	0.384
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.001	0.616	0.383
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.619	0.380
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.619	0.380
M30.2 Juvenile polyarteritis	0.000	0.619	0.380
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.623	0.377
M24.2 Disorder of ligament	0.000	0.626	0.374
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.627	0.373
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.627	0.373
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.627	0.373
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.627	0.373
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.627	0.373
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.627	0.373
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.627	0.372
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.631	0.369
M24.54 Contracture of joint (Hand)	0.000	0.632	0.368
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.635	0.365
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.636	0.364
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.638	0.362
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.639	0.360
M21.27 Flexion deformity (Ankle and foot)	0.000	0.651	0.349
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.668	0.332
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.669	0.331
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.669	0.331
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.669	0.331
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.669	0.331
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.669	0.331
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.669	0.331
M25 Other joint disorders, not elsewhere classified	0.000	0.669	0.331
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.671	0.329
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.680	0.320
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.680	0.320
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.680	0.320
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.680	0.320
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.680	0.320
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.680	0.320
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.680	0.320
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.680	0.320
M30.0 Polyarteritis nodosa	0.000	0.685	0.315
M34.1 CR(E)ST syndrome	0.000	0.692	0.308
M34.0 Progressive systemic sclerosis	0.000	0.697	0.303
K44 Diaphragmatic hernia	0.000	0.697	0.303
M24.24 Disorder of ligament (Hand)	0.000	0.700	0.300
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.702	0.298
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.702	0.297
M24.23 Disorder of ligament (Forearm)	0.000	0.705	0.295
M21.29 Flexion deformity (Site unspecified)	0.000	0.708	0.291
M21.28 Flexion deformity (Other)	0.000	0.708	0.291
M21.23 Flexion deformity (Forearm)	0.000	0.708	0.291
M21.22 Flexion deformity (Upper arm)	0.000	0.708	0.291
M21.21 Flexion deformity (Shoulder region)	0.000	0.708	0.291
M21.20 Flexion deformity (Multiple sites)	0.000	0.708	0.291
M25.76 Osteophyte (Lower leg)	0.000	0.714	0.286
M25.7 Osteophyte	0.000	0.714	0.286
M34.9 Systemic sclerosis, unspecified	0.000	0.716	0.284
M25.3 Other instability of joint	0.000	0.718	0.282
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.720	0.280
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.724	0.276
M21.78 Unequal limb length (acquired)-Other	0.001	0.724	0.276
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.724	0.276
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.724	0.276
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.724	0.276
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.724	0.276
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.724	0.276
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.729	0.271
M24.29 Disorder of ligament (Site unspecified)	0.000	0.731	0.268
M24.22 Disorder of ligament (Upper arm)	0.000	0.731	0.268
M24.20 Disorder of ligament (Multiple sites)	0.000	0.731	0.268
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.732	0.267
M34.8 Other forms of systemic sclerosis	0.000	0.733	0.267
M24.26 Disorder of ligament (Lower leg)	0.000	0.734	0.266
M25.34 Other instability of joint (Hand)	0.000	0.742	0.258
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.751	0.248
M25.56 Pain in joint (Lower leg)	0.000	0.754	0.246
M25.72 Osteophyte (Upper arm)	0.000	0.756	0.244
M25.8 Other specified joint disorders	0.000	0.758	0.242
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.759	0.240
M25.2 Flail joint	0.000	0.763	0.237
M25.1 Fistula of joint	0.000	0.763	0.237
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.765	0.235
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.768	0.232
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.001	0.770	0.230
M65.34 Trigger finger-Hand	0.000	0.775	0.225
M21.24 Flexion deformity (Hand)	0.001	0.777	0.222
M25.0 Haemarthrosis	0.000	0.778	0.221
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.780	0.219
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.781	0.218
M25.36 Other instability of joint (Lower leg)	0.000	0.786	0.214
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.787	0.213
M25.33 Other instability of joint (Forearm)	0.000	0.789	0.211
M24.0 Loose body in joint	0.001	0.789	0.210
M24.28 Disorder of ligament (Other)	0.001	0.790	0.210
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.790	0.210
M25.5 Pain in joint	0.000	0.792	0.208
M25.74 Osteophyte (Hand)	0.000	0.792	0.208
M25.70 Osteophyte (Multiple sites)	0.000	0.795	0.205
M25.73 Osteophyte (Forearm)	0.000	0.798	0.202
M25.39 Other instability of joint (Site unspecified)	0.000	0.798	0.202
M25.38 Other instability of joint (Other)	0.000	0.798	0.202
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.798	0.202
M25.32 Other instability of joint (Upper arm)	0.000	0.798	0.202
M25.30 Other instability of joint (Multiple sites)	0.000	0.798	0.202
M21.26 Flexion deformity (Lower leg)	0.001	0.798	0.201
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.802	0.197
M25.83 Other specified joint disorders (Forearm)	0.000	0.809	0.190
M25.71 Osteophyte (Shoulder region)	0.000	0.811	0.188
M15-M19 Arthrosis	0.000	0.813	0.187
M25.37 Other instability of joint (Ankle and foot)	0.000	0.813	0.187
M65.3 Trigger finger	0.000	0.815	0.185
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.184	0.816	0.000
I80 Phlebitis and thrombophlebitis	0.182	0.818	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.181	0.819	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.824	0.176
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.826	0.174
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.826	0.174
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.829	0.171
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.171	0.829	0.000
M25.19 Fistula of joint (Site unspecified)	0.000	0.830	0.170
M25.18 Fistula of joint (Other)	0.000	0.830	0.170
M25.17 Fistula of joint (Ankle and foot)	0.000	0.830	0.170
M25.16 Fistula of joint (Lower leg)	0.000	0.830	0.170
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.830	0.170
M25.14 Fistula of joint (Hand)	0.000	0.830	0.170
M25.13 Fistula of joint (Forearm)	0.000	0.830	0.170
M25.12 Fistula of joint (Upper arm)	0.000	0.830	0.170
M25.11 Fistula of joint (Shoulder region)	0.000	0.830	0.170
M25.10 Fistula of joint (Multiple sites)	0.000	0.830	0.170
M25.29 Flail joint (Site unspecified)	0.000	0.830	0.170
M25.28 Flail joint (Other)	0.000	0.830	0.170
M25.27 Flail joint (Ankle and foot)	0.000	0.830	0.170
M25.26 Flail joint (Lower leg)	0.000	0.830	0.170
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.830	0.170
M25.24 Flail joint (Hand)	0.000	0.830	0.170
M25.23 Flail joint (Forearm)	0.000	0.830	0.170
M25.22 Flail joint (Upper arm)	0.000	0.830	0.170
M25.21 Flail joint (Shoulder region)	0.000	0.830	0.170
M25.20 Flail joint (Multiple sites)	0.000	0.830	0.170
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.170	0.830	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.837	0.163
M25.09 Haemarthrosis (Site unspecified)	0.000	0.841	0.159
M25.08 Haemarthrosis (Other)	0.000	0.841	0.159
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.841	0.159
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.841	0.159
M25.04 Haemarthrosis (Hand)	0.000	0.841	0.159
M25.03 Haemarthrosis (Forearm)	0.000	0.841	0.159
M25.02 Haemarthrosis (Upper arm)	0.000	0.841	0.159
M25.01 Haemarthrosis (Shoulder region)	0.000	0.841	0.159
M25.00 Haemarthrosis (Multiple sites)	0.000	0.841	0.159
M25.82 Other specified joint disorders (Upper arm)	0.000	0.842	0.158
M65-M68 Disorders of synovium and tendon	0.000	0.842	0.158
M24.06 Loose body in joint-Lower leg	0.001	0.844	0.155
K44.1 Diaphragmatic hernia with gangrene	0.000	0.844	0.156
M65 Synovitis and tenosynovitis	0.000	0.844	0.156
M24.21 Disorder of ligament (Shoulder region)	0.001	0.845	0.153
M25.31 Other instability of joint (Shoulder region)	0.000	0.848	0.152
M24.09 Loose body in joint (Site unspecified)	0.001	0.849	0.150
M24.08 Loose body in joint (Other)	0.001	0.849	0.150
M24.04 Loose body in joint (Hand)	0.001	0.849	0.150
M24.00 Loose body in joint (Multiple sites)	0.001	0.849	0.150
M25.53 Pain in joint (Forearm)	0.000	0.850	0.150
M25.77 Osteophyte (Ankle and foot)	0.000	0.851	0.149
M25.84 Other specified joint disorders (Hand)	0.000	0.855	0.145
M35 Other systemic involvement of connective tissue	0.000	0.856	0.144
M25.06 Haemarthrosis (Lower leg)	0.000	0.857	0.143
M25.86 Other specified joint disorders (Lower leg)	0.000	0.858	0.142
M25.54 Pain in joint (Hand)	0.000	0.860	0.140
M15 Polyarthrosis	0.000	0.862	0.138
M31 Other necrotising vasculopathies	0.000	0.865	0.134
M24.07 Loose body in joint (Ankle and foot)	0.001	0.866	0.134
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.866	0.133
M65.39 Trigger finger-Site unspec	0.000	0.867	0.132
M65.38 Trigger finger-Other	0.000	0.867	0.132
M65.37 Trigger finger-Ankle/foot	0.000	0.867	0.132
M65.36 Trigger finger-Lower leg	0.000	0.867	0.132
M65.35 Trigger finger-Pelvic/thigh	0.000	0.867	0.132
M65.33 Trigger finger-Forearm	0.000	0.867	0.132
M65.32 Trigger finger-Upper arm	0.000	0.867	0.132
M65.31 Trigger finger-Shldr region	0.000	0.867	0.132
M65.30 Trigger finger-Mult sites	0.000	0.867	0.132
M25.4 Effusion of joint	0.000	0.870	0.130
M25.9 Joint disorder, unspecified	0.000	0.871	0.129
M25.88 Other specified joint disorders (Other)	0.000	0.871	0.128
M25.58 Pain in joint (Other)	0.000	0.873	0.127
M24.03 Loose body in joint (Forearm)	0.001	0.876	0.123
M91-M94 Chondropathies	0.000	0.879	0.121
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.883	0.117
M35.1 Other overlap syndromes	0.000	0.885	0.115
M66 Spontaneous rupture of synovium and tendon	0.000	0.886	0.114
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.000	0.886	0.113
M25.43 Effusion of joint (Forearm)	0.000	0.888	0.112
M65.0 Abscess of tendon sheath	0.000	0.888	0.112
M65.2 Calcific tendinitis	0.000	0.891	0.109
M67 Other disorders of synovium and tendon	0.000	0.892	0.108
M15.1 Heberden's nodes (with arthropathy)	0.000	0.894	0.106
M93 Other osteochondropathies	0.000	0.894	0.106
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.895	0.105
M24.01 Loose body in joint (Shoulder region)	0.001	0.895	0.104
M15.3 Secondary multiple arthrosis	0.000	0.896	0.104
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.897	0.103
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.897	0.103
M35.5 Multifocal fibrosclerosis	0.000	0.897	0.103
M35.7 Hypermobility syndrome	0.000	0.897	0.102
M15.9 Polyarthrosis, unspecified	0.000	0.898	0.102
M86-M90 Other osteopathies	0.000	0.899	0.101
M31.1 Thrombotic microangiopathy	0.000	0.899	0.100
M60-M63 Disorders of muscles	0.000	0.900	0.100
M65.1 Other infective (teno)synovitis	0.000	0.900	0.100
M15.8 Other polyarthrosis	0.000	0.900	0.100
M15.0 Primary generalised (osteo)arthrosis	0.000	0.901	0.099
M25.40 Effusion of joint (Multiple sites)	0.000	0.901	0.099
M25.44 Effusion of joint (Hand)	0.000	0.901	0.098
M31.2 Lethal midline granuloma	0.000	0.903	0.096
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.903	0.097
M31.7 Microscopic polyangiitis	0.000	0.905	0.095
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.905	0.095
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.905	0.095

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations