TreeWAS – Variant ID: rs2249464

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E03 Other hypothyroidism	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.999	0.001	0.000
E83.1 Disorders of iron metabolism	0.999	0.001	0.000
L40.9 Psoriasis, unspecified	0.000	0.034	0.966
E06 Thyroiditis	0.939	0.061	0.000
L40 Psoriasis	0.000	0.097	0.903
L40.5 Arthropathic psoriasis	0.000	0.111	0.889
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.129	0.871
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.859	0.141	0.000
E06.3 Autoimmune thyroiditis	0.830	0.170	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.817	0.183	0.000
E03.8 Other specified hypothyroidism	0.817	0.183	0.000
E06.9 Thyroiditis, unspecified	0.815	0.185	0.000
L40.0 Psoriasis vulgaris	0.000	0.239	0.761
E03.1 Congenital hypothyroidism without goitre	0.739	0.261	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.734	0.266	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E06.5 Other chronic thyroiditis	0.715	0.285	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.709	0.291	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.300	0.700
E05.8 Other thyrotoxicosis	0.698	0.302	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.303	0.697
M06 Other rheumatoid arthritis	0.000	0.308	0.692
M06.9 Rheumatoid arthritis, unspecified	0.000	0.313	0.687
M05 Seropositive rheumatoid arthritis	0.000	0.319	0.681
L40.1 Generalised pustular psoriasis	0.000	0.325	0.675
E06.4 Drug-induced thyroiditis	0.673	0.327	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.673	0.327	0.000
E06.0 Acute thyroiditis	0.673	0.327	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.329	0.671
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.331	0.669
E06.1 Subacute thyroiditis	0.666	0.334	0.000
M06.3 Rheumatoid nodule	0.000	0.338	0.662
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.343	0.657
L40.2 Acrodermatitis continua	0.000	0.353	0.647
E07 Other disorders of thyroid	0.622	0.378	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.386	0.614
M06.34 Rheumatoid nodule (Hand)	0.000	0.393	0.607
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.393	0.607
M06.0 Seronegative rheumatoid arthritis	0.000	0.394	0.606
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.605	0.395	0.000
L40.8 Other psoriasis	0.000	0.401	0.599
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.407	0.593
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.413	0.587
L40.4 Guttate psoriasis	0.000	0.422	0.577
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.424	0.576
M07 Psoriatic and enteropathic arthropathies	0.000	0.424	0.576
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.431	0.569
K90 Intestinal malabsorption	0.567	0.433	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.436	0.564
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.454	0.546
M06.4 Inflammatory polyarthropathy	0.000	0.457	0.543
M07.3 Other psoriatic arthropathies	0.000	0.472	0.528
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.477	0.523
L40.3 Pustulosis palmaris et plantaris	0.000	0.483	0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.489	0.511
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.489	0.511
K90.9 Intestinal malabsorption, unspecified	0.507	0.493	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.498	0.502
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.498	0.502
Chapter IV Endocrine, nutritional and metabolic diseases	0.501	0.499	0.000
M12 Other specific arthropathies	0.000	0.499	0.500
M06.2 Rheumatoid bursitis	0.000	0.504	0.496
M06.1 Adult-onset Still's disease	0.000	0.504	0.496
M08 Juvenile arthritis	0.000	0.505	0.495
E83 Disorders of mineral metabolism	0.492	0.508	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.511	0.489
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.511	0.489
M05.1 Rheumatoid lung disease	0.000	0.511	0.489
M05.0 Felty's syndrome	0.000	0.511	0.489
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.512	0.488
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.518	0.481
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.520	0.479
M05.8 Other seropositive rheumatoid arthritis	0.000	0.524	0.476
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.526	0.474
M06.38 Rheumatoid nodule (Other)	0.000	0.526	0.474
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.526	0.474
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.526	0.474
M06.33 Rheumatoid nodule (Forearm)	0.000	0.526	0.474
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.526	0.474
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.527	0.473
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.528	0.472
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.541	0.459
M05.2 Rheumatoid vasculitis	0.000	0.542	0.458
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.542	0.458
M06.8 Other specified rheumatoid arthritis	0.000	0.543	0.457
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.547	0.453
E07.1 Dyshormogenetic goitre	0.446	0.554	0.000
E07.0 Hypersecretion of calcitonin	0.446	0.554	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.443	0.557	0.000
E70-E90 Metabolic disorders	0.442	0.557	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.561	0.439
M45 Ankylosing spondylitis	0.000	0.561	0.439
E27.1 Primary adrenocortical insufficiency	0.439	0.561	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.563	0.437
E27 Other disorders of adrenal gland	0.436	0.564	0.000
E20-E35 Disorders of other endocrine glands	0.434	0.566	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.566	0.434
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.566	0.434
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.566	0.434
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.569	0.431
E07.9 Disorder of thyroid, unspecified	0.431	0.569	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.571	0.428
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.574	0.426
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.574	0.425
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.577	0.423
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.581	0.419
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.581	0.419
D86.9 Sarcoidosis, unspecified	0.417	0.583	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.416	0.584	0.000
M07.5 Arthropathy in ulcerative colitis	0.000	0.587	0.413
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.587	0.413
M07.2 Psoriatic spondylitis	0.000	0.587	0.413
M07.1 Arthritis mutilans	0.000	0.587	0.413
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.587	0.413
D86 Sarcoidosis	0.407	0.593	0.000
K90.3 Pancreatic steatorrhoea	0.406	0.593	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.406	0.593	0.000
K90.1 Tropical sprue	0.406	0.593	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.594	0.406
E16 Other disorders of pancreatic internal secretion	0.402	0.598	0.000
M12.2 Villonodular synovitis (pigmented)	0.000	0.601	0.399
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.603	0.397
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.604	0.396
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.610	0.389
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.610	0.389
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.610	0.389
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.610	0.389
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.610	0.389
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.610	0.389
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.610	0.389
E16.2 Hypoglycaemia, unspecified	0.386	0.614	0.000
D80-D89 Certain disorders involving the immune mechanism	0.385	0.615	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.621	0.379
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.621	0.379
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.621	0.379
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.621	0.379
M12.5 Traumatic arthropathy	0.000	0.624	0.375
E07.8 Other specified disorders of thyroid	0.373	0.627	0.000
E50-E64 Other nutritional deficiencies	0.373	0.627	0.000
M08.0 Juvenile rheumatoid arthritis	0.000	0.631	0.369
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.637	0.363
E29 Testicular dysfunction	0.361	0.639	0.000
M12.4 Intermittent hydrarthrosis	0.000	0.641	0.359
M12.1 Kaschin-Beck disease	0.000	0.641	0.359
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.641	0.359
D86.8 Sarcoidosis of other and combined sites	0.356	0.644	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.644	0.356
M06.18 Adult-onset Still's disease (Other)	0.000	0.644	0.356
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.644	0.356
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.644	0.356
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.644	0.356
M06.14 Adult-onset Still's disease (Hand)	0.000	0.644	0.356
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.644	0.356
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.644	0.356
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.644	0.356
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.644	0.356
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.644	0.356
M06.28 Rheumatoid bursitis (Other)	0.000	0.644	0.356
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.644	0.356
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.644	0.356
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.644	0.356
M06.24 Rheumatoid bursitis (Hand)	0.000	0.644	0.356
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.644	0.356
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.644	0.356
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.644	0.356
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.644	0.356
M08.9 Juvenile arthritis, unspecified	0.000	0.645	0.355
M08.8 Other juvenile arthritis	0.000	0.645	0.355
M08.4 Pauciarticular juvenile arthritis	0.000	0.645	0.355
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.645	0.355
M08.2 Juvenile arthritis with systemic onset	0.000	0.645	0.355
M08.1 Juvenile ankylosing spondylitis	0.000	0.645	0.355
E83.8 Other disorders of mineral metabolism	0.353	0.647	0.000
E83.2 Disorders of zinc metabolism	0.353	0.647	0.000
E83.0 Disorders of copper metabolism	0.353	0.647	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.649	0.350
M05.08 Felty's syndrome (Other)	0.000	0.649	0.350
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.649	0.350
M05.06 Felty's syndrome (Lower leg)	0.000	0.649	0.350
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.649	0.350
M05.04 Felty's syndrome (Hand)	0.000	0.649	0.350
M05.03 Felty's syndrome (Forearm)	0.000	0.649	0.350
M05.02 Felty's syndrome (Upper arm)	0.000	0.649	0.350
M05.01 Felty's syndrome (Shoulder region)	0.000	0.649	0.350
M05.00 Felty's syndrome (Multiple sites)	0.000	0.649	0.350
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.649	0.350
M05.18 Rheumatoid lung disease (Other)	0.000	0.649	0.350
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.649	0.350
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.649	0.350
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.649	0.350
M05.14 Rheumatoid lung disease (Hand)	0.000	0.649	0.350
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.649	0.350
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.649	0.350
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.649	0.350
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.649	0.350
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.649	0.350
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.649	0.350
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.649	0.350
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.649	0.350
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.649	0.350
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.649	0.350
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.649	0.350
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.649	0.350
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.649	0.350
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.649	0.350
E83.9 Disorder of mineral metabolism, unspecified	0.349	0.651	0.000
D80 Immunodeficiency with predominantly antibody defects	0.349	0.651	0.000
E88 Other metabolic disorders	0.349	0.651	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.652	0.348
E27.4 Other and unspecified adrenocortical insufficiency	0.346	0.654	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.654	0.345
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.655	0.345
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.655	0.345
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.655	0.345
M09.0 Juvenile arthritis in psoriasis	0.000	0.655	0.345
E31 Polyglandular dysfunction	0.345	0.655	0.000
M07.6 Other enteropathic arthropathies	0.000	0.655	0.344
D86.0 Sarcoidosis of lung	0.344	0.656	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.342	0.658	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.659	0.341
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.659	0.341
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.659	0.341
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.659	0.341
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.659	0.341
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.659	0.341
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.659	0.341
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.659	0.341
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.659	0.341
E27.8 Other specified disorders of adrenal gland	0.339	0.661	0.000
M12.3 Palindromic rheumatism	0.000	0.663	0.337
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.667	0.333
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.667	0.332
E84 Cystic fibrosis	0.332	0.668	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.669	0.330
M13 Other arthritis	0.000	0.670	0.330
M05.28 Rheumatoid vasculitis (Other)	0.000	0.671	0.328
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.671	0.328
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.671	0.328
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.671	0.328
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.671	0.328
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.671	0.328
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.671	0.328
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.671	0.328
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.671	0.328
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.672	0.328
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.672	0.328
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.672	0.328
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.672	0.328
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.672	0.328
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.672	0.328
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.672	0.328
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.672	0.328
E25 Adrenogenital disorders	0.328	0.672	0.000
E73 Lactose intolerance	0.325	0.675	0.000
E61 Deficiency of other nutrient elements	0.325	0.675	0.000
D86.1 Sarcoidosis of lymph nodes	0.322	0.678	0.000
M11 Other crystal arthropathies	0.000	0.679	0.321
E27.3 Drug-induced adrenocortical insufficiency	0.320	0.680	0.000
E15 Nondiabetic hypoglycaemic coma	0.318	0.682	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.318	0.682	0.000
E77 Disorders of glycoprotein metabolism	0.317	0.683	0.000
E76 Disorders of glycosaminoglycan metabolism	0.317	0.683	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.317	0.683	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.317	0.683	0.000
E20 Hypoparathyroidism	0.317	0.683	0.000
E72 Other disorders of amino-acid metabolism	0.316	0.684	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.685	0.315
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.685	0.315
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.685	0.315
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.685	0.315
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.685	0.315
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.685	0.315
K31.7 Polyp of stomach and duodenum	0.000	0.685	0.315
E70 Disorders of aromatic amino-acid metabolism	0.314	0.686	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.686	0.313
M14.4 Arthropathy in amyloidosis	0.000	0.686	0.313
M14.3 Lipoid dermatoarthritis	0.000	0.686	0.313
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.686	0.313
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.686	0.313
E27.5 Adrenomedullary hyperfunction	0.312	0.687	0.000
E27.0 Other adrenocortical overactivity	0.312	0.687	0.000
D83 Common variable immunodeficiency	0.312	0.687	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.312	0.688	0.000
E32 Diseases of thymus	0.312	0.688	0.000
E30 Disorders of puberty, not elsewhere classified	0.312	0.688	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.309	0.691	0.000
E74 Other disorders of carbohydrate metabolism	0.306	0.693	0.000
M14.2 Diabetic arthropathy	0.000	0.694	0.306
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.694	0.306
E79 Disorders of purine and pyrimidine metabolism	0.304	0.696	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.696	0.304
E29.1 Testicular hypofunction	0.302	0.697	0.000
M14.6 Neuropathic arthropathy	0.000	0.698	0.302
E40-E46 Malnutrition	0.301	0.699	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.703	0.297
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.704	0.296
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.704	0.296
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.704	0.296
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.704	0.296
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.704	0.296
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.704	0.296
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.704	0.296
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.704	0.296
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.704	0.296
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.704	0.296
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.704	0.296
M07.18 Arthritis mutilans (Other)	0.000	0.704	0.296
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.704	0.296
M07.16 Arthritis mutilans (Lower leg)	0.000	0.704	0.296
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.704	0.296
M07.14 Arthritis mutilans (Hand)	0.000	0.704	0.296
M07.13 Arthritis mutilans (Forearm)	0.000	0.704	0.296
M07.12 Arthritis mutilans (Upper arm)	0.000	0.704	0.296
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.704	0.296
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.704	0.296
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.704	0.296
M07.28 Psoriatic spondylitis (Other)	0.000	0.704	0.296
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.704	0.296
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.704	0.296
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.704	0.296
M07.24 Psoriatic spondylitis (Hand)	0.000	0.704	0.296
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.704	0.296
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.704	0.296
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.704	0.296
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.704	0.296
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.704	0.296
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.704	0.296
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.704	0.296
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.704	0.296
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.704	0.296
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.704	0.296
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.704	0.296
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.704	0.296
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.704	0.296
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.704	0.296
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.704	0.296
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.704	0.296
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.704	0.296
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.704	0.296
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.704	0.296
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.704	0.296
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.704	0.296
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.704	0.296
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.704	0.296
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.704	0.296
K90.8 Other intestinal malabsorption	0.293	0.706	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.707	0.293
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.707	0.293
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.707	0.292
D84 Other immunodeficiencies	0.291	0.708	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.710	0.290
E16.9 Disorder of pancreatic internal secretion, unspecified	0.288	0.712	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.288	0.712	0.000
E16.4 Abnormal secretion of gastrin	0.288	0.712	0.000
E16.3 Increased secretion of glucagon	0.288	0.712	0.000
E61.2 Magnesium deficiency	0.288	0.712	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.000	0.714	0.286
M12.28 Villonodular synovitis (pigmented) (Other)	0.000	0.714	0.286
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.000	0.714	0.286
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.000	0.714	0.286
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.000	0.714	0.286
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.000	0.714	0.286
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.000	0.714	0.286
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.000	0.714	0.286
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.286	0.714	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.000	0.714	0.286
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.284	0.716	0.000
E83.5 Disorders of calcium metabolism	0.284	0.716	0.000
E27.2 Addisonian crisis	0.283	0.717	0.000
E31.0 Autoimmune polyglandular failure	0.281	0.719	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.000	0.720	0.280
E51 Thiamine deficiency	0.279	0.721	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.000	0.721	0.279
D81 Combined immunodeficiencies	0.276	0.724	0.000
E88.9 Metabolic disorder, unspecified	0.275	0.724	0.000
E58 Dietary calcium deficiency	0.275	0.725	0.000
E63 Other nutritional deficiencies	0.273	0.727	0.000
E75.5 Other lipid storage disorders	0.269	0.730	0.000
M12.59 Traumatic arthropathy (Site unspecified)	0.000	0.730	0.269
M12.58 Traumatic arthropathy (Other)	0.000	0.730	0.269
M12.56 Traumatic arthropathy (Lower leg)	0.000	0.730	0.269
M12.55 Traumatic arthropathy (Pelvic region and thigh)	0.000	0.730	0.269
M12.54 Traumatic arthropathy (Hand)	0.000	0.730	0.269
M12.53 Traumatic arthropathy (Forearm)	0.000	0.730	0.269
M12.52 Traumatic arthropathy (Upper arm)	0.000	0.730	0.269
M12.51 Traumatic arthropathy (Shoulder region)	0.000	0.730	0.269
M12.50 Traumatic arthropathy (Multiple sites)	0.000	0.730	0.269
E26 Hyperaldosteronism	0.268	0.731	0.000
E29.9 Testicular dysfunction, unspecified	0.268	0.732	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.267	0.733	0.000
E50 Vitamin A deficiency	0.267	0.733	0.000
E60 Dietary zinc deficiency	0.267	0.733	0.000
E59 Dietary selenium deficiency	0.267	0.733	0.000
E54 Ascorbic acid deficiency	0.267	0.733	0.000
E52 Niacin deficiency [pellagra]	0.267	0.733	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.000	0.735	0.265
M08.08 Juvenile rheumatoid arthritis (Other)	0.000	0.735	0.265
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.000	0.735	0.265
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.000	0.735	0.265
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.000	0.735	0.265
M08.04 Juvenile rheumatoid arthritis (Hand)	0.000	0.735	0.265
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.000	0.735	0.265
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.000	0.735	0.265
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.000	0.735	0.265
E27.9 Disorder of adrenal gland, unspecified	0.265	0.735	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.264	0.736	0.000
E88.8 Other specified metabolic disorders	0.264	0.736	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.264	0.736	0.000
M13.8 Other specified arthritis	0.000	0.736	0.264
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.737	0.263
D82 Immunodeficiency associated with other major defects	0.262	0.738	0.000
D83.9 Common variable immunodeficiency, unspecified	0.261	0.739	0.000
D50-D53 Nutritional anaemias	0.259	0.741	0.000
E29.8 Other testicular dysfunction	0.259	0.741	0.000
E29.0 Testicular hyperfunction	0.259	0.741	0.000
D89.1 Cryoglobulinaemia	0.258	0.742	0.000
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.000	0.742	0.257
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.000	0.742	0.257
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.000	0.742	0.257
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.000	0.742	0.257
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.000	0.742	0.257
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.000	0.742	0.257
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.000	0.742	0.257
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.000	0.742	0.257
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.000	0.742	0.257
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.000	0.742	0.257
M12.19 Kaschin-Beck disease (Site unspecified)	0.000	0.742	0.257
M12.18 Kaschin-Beck disease (Other)	0.000	0.742	0.257
M12.17 Kaschin-Beck disease (Ankle and foot)	0.000	0.742	0.257
M12.16 Kaschin-Beck disease (Lower leg)	0.000	0.742	0.257
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.000	0.742	0.257
M12.14 Kaschin-Beck disease (Hand)	0.000	0.742	0.257
M12.13 Kaschin-Beck disease (Forearm)	0.000	0.742	0.257
M12.12 Kaschin-Beck disease (Upper arm)	0.000	0.742	0.257
M12.11 Kaschin-Beck disease (Shoulder region)	0.000	0.742	0.257
M12.10 Kaschin-Beck disease (Multiple sites)	0.000	0.742	0.257
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.000	0.742	0.257
M12.48 Intermittent hydrarthrosis (Other)	0.000	0.742	0.257
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.000	0.742	0.257
M12.46 Intermittent hydrarthrosis (Lower leg)	0.000	0.742	0.257
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.000	0.742	0.257
M12.44 Intermittent hydrarthrosis (Hand)	0.000	0.742	0.257
M12.43 Intermittent hydrarthrosis (Forearm)	0.000	0.742	0.257
M12.42 Intermittent hydrarthrosis (Upper arm)	0.000	0.742	0.257
M12.41 Intermittent hydrarthrosis (Shoulder region)	0.000	0.742	0.257
M12.40 Intermittent hydrarthrosis (Multiple sites)	0.000	0.742	0.257
E83.4 Disorders of magnesium metabolism	0.257	0.743	0.000
D50.8 Other iron deficiency anaemias	0.256	0.744	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.256	0.744	0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.000	0.745	0.255
M08.18 Juvenile ankylosing spondylitis (Other)	0.000	0.745	0.255
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.000	0.745	0.255
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.000	0.745	0.255
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.000	0.745	0.255
M08.14 Juvenile ankylosing spondylitis (Hand)	0.000	0.745	0.255
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.000	0.745	0.255
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.000	0.745	0.255
M08.11 Juvenile ankylosing spondylitis (Shoulder region)	0.000	0.745	0.255
M08.10 Juvenile ankylosing spondylitis (Multiple sites)	0.000	0.745	0.255
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.000	0.745	0.255
M08.28 Juvenile arthritis with systemic onset (Other)	0.000	0.745	0.255
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)	0.000	0.745	0.255
M08.26 Juvenile arthritis with systemic onset (Lower leg)	0.000	0.745	0.255
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)	0.000	0.745	0.255
M08.24 Juvenile arthritis with systemic onset (Hand)	0.000	0.745	0.255
M08.23 Juvenile arthritis with systemic onset (Forearm)	0.000	0.745	0.255
M08.22 Juvenile arthritis with systemic onset (Upper arm)	0.000	0.745	0.255
M08.21 Juvenile arthritis with systemic onset (Shoulder region)	0.000	0.745	0.255
M08.20 Juvenile arthritis with systemic onset (Multiple sites)	0.000	0.745	0.255
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)	0.000	0.745	0.255
M08.38 Juvenile polyarthritis (seronegative) (Other)	0.000	0.745	0.255
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)	0.000	0.745	0.255
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)	0.000	0.745	0.255
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)	0.000	0.745	0.255
M08.34 Juvenile polyarthritis (seronegative) (Hand)	0.000	0.745	0.255
M08.33 Juvenile polyarthritis (seronegative) (Forearm)	0.000	0.745	0.255
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)	0.000	0.745	0.255
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)	0.000	0.745	0.255

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations