TreeWAS – Variant ID: rs225694

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I63 Cerebral infarction	0.997	0.003	0.000
I60-I69 Cerebrovascular diseases	0.997	0.003	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.995	0.005	0.000
I63.9 Cerebral infarction, unspecified	0.994	0.006	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.963	0.037	0.000
I69 Sequelae of cerebrovascular disease	0.918	0.082	0.000
I69.3 Sequelae of cerebral infarction	0.894	0.106	0.000
I60 Subarachnoid haemorrhage	0.866	0.134	0.000
I63.8 Other cerebral infarction	0.863	0.137	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.811	0.189	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.799	0.201	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.798	0.202	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.787	0.213	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.786	0.214	0.000
I61 Intracerebral haemorrhage	0.755	0.245	0.000
I60.8 Other subarachnoid haemorrhage	0.755	0.245	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.727	0.273	0.000
I67 Other cerebrovascular diseases	0.719	0.281	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.715	0.285	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.715	0.285	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.714	0.286	0.000
I62 Other nontraumatic intracranial haemorrhage	0.706	0.294	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.699	0.301	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.686	0.314	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.681	0.319	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.668	0.332	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.661	0.339	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.660	0.340	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.648	0.351	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.648	0.352	0.000
I67.2 Cerebral atherosclerosis	0.643	0.357	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.638	0.362	0.000
I65.2 Occlusion and stenosis of carotid artery	0.632	0.368	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.625	0.375	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.621	0.379	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.606	0.394	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.605	0.395	0.000
I65.1 Occlusion and stenosis of basilar artery	0.604	0.396	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.601	0.399	0.000
I67.9 Cerebrovascular disease, unspecified	0.600	0.400	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.590	0.410	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.587	0.413	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.586	0.414	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.582	0.418	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.580	0.420	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.572	0.428	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.572	0.428	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.553	0.447	0.000
I61.8 Other intracerebral haemorrhage	0.552	0.448	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.547	0.453	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.547	0.453	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.536	0.464	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.536	0.464	0.000
I67.4 Hypertensive encephalopathy	0.529	0.471	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.528	0.472	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.524	0.475	0.000
I67.5 Moyamoya disease	0.516	0.484	0.000
I67.3 Progressive vascular leukoencephalopathy	0.516	0.484	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.507	0.493	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.501	0.498	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.501	0.498	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.501	0.498	0.000
I62.1 Nontraumatic extradural haemorrhage	0.498	0.501	0.000
I68.0 Cerebral amyloid angiopathy	0.486	0.514	0.000
I67.1 Cerebral aneurysm, nonruptured	0.457	0.543	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.455	0.545	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.454	0.546	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.432	0.567	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.428	0.572	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.426	0.573	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.416	0.584	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.414	0.585	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.390	0.610	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.387	0.613	0.000
I67.8 Other specified cerebrovascular diseases	0.290	0.710	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.740	0.260
H54 Blindness and low vision	0.000	0.945	0.055
H54.9 Unspecified visual impairment (binocular)	0.000	0.945	0.055
H54.0 Blindness, both eyes	0.000	0.949	0.051
H54.7 Unspecified visual loss	0.000	0.951	0.049
H54.6 Unqualified visual loss, one eye	0.000	0.955	0.045
H54.5 Low vision, one eye	0.000	0.955	0.045
H54.4 Blindness, one eye	0.000	0.956	0.044
H54.1 Blindness, one eye, low vision, other eye	0.000	0.960	0.040
H54.2 Low vision, both eyes	0.000	0.960	0.040
H54.3 Unqualified visual loss, both eyes	0.000	0.962	0.038
H53-H54 Visual disturbances and blindness	0.000	0.978	0.022
H53.1 Subjective visual disturbances	0.000	0.980	0.020
H53 Visual disturbances	0.000	0.985	0.015
Q21.1 Atrial septal defect	0.013	0.987	0.000
S02.20 Fracture of nasal bones (closed)	0.012	0.988	0.000
H53.5 Colour vision deficiencies	0.000	0.988	0.011
H53.6 Night blindness	0.000	0.989	0.011
H53.2 Diplopia	0.000	0.989	0.011
H53.3 Other disorders of binocular vision	0.000	0.989	0.011
K22.2 Oesophageal obstruction	0.000	0.989	0.011
K56.7 Ileus, unspecified	0.000	0.990	0.010
H53.9 Visual disturbance, unspecified	0.000	0.990	0.010
T92.2 Sequelae of fracture at wrist and hand level	0.010	0.990	0.000
T92 Sequelae of injuries of upper limb	0.009	0.991	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.009	0.991	0.000
Q21 Congenital malformations of cardiac septa	0.008	0.991	0.000
T92.1 Sequelae of fracture of arm	0.008	0.992	0.000
I05.9 Mitral valve disease, unspecified	0.008	0.992	0.000
T92.0 Sequelae of open wound of upper limb	0.008	0.992	0.000
S02.2 Fracture of nasal bones	0.008	0.992	0.000
I05 Rheumatic mitral valve diseases	0.007	0.993	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.007	0.993	0.000
I05.2 Mitral stenosis with insufficiency	0.007	0.993	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.007	0.993	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.007	0.993	0.000
I05.0 Mitral stenosis	0.007	0.993	0.000
Q24 Other congenital malformations of heart	0.007	0.993	0.000
T90.9 Sequelae of unspecified injury of head	0.007	0.993	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.007	0.993	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q21.4 Aortopulmonary septal defect	0.006	0.994	0.000
Q21.2 Atrioventricular septal defect	0.006	0.994	0.000
S02.21 Fracture of nasal bones (open)	0.006	0.994	0.000
K63.9 Disease of intestine, unspecified	0.006	0.994	0.000
T90 Sequelae of injuries of head	0.006	0.994	0.000
Q21.0 Ventricular septal defect	0.006	0.994	0.000
E87.2 Acidosis	0.006	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.006	0.994	0.000
I05.8 Other mitral valve diseases	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
Q21.3 Tetralogy of Fallot	0.006	0.994	0.000
Q21.8 Other congenital malformations of cardiac septa	0.006	0.994	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.006	0.994	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.006	0.994	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.005	0.994	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.994	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.005	0.994	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
T91 Sequelae of injuries of neck and trunk	0.005	0.995	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.005	0.995	0.000
T90.0 Sequelae of superficial injury of head	0.005	0.995	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
D41.4 Bladder	0.005	0.995	0.000
Z39.1 Care and examination of lactating mother	0.000	0.995	0.005
T90.8 Sequelae of other specified injuries of head	0.005	0.995	0.000
Q24.6 Congenital heart block	0.005	0.995	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.005	0.995	0.000
Q24.5 Malformation of coronary vessels	0.005	0.995	0.000
T95 Sequelae of burns, corrosions and frostbite	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.005	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.005	0.995	0.000
Y86 Sequelae of other accidents	0.005	0.995	0.000
T90.3 Sequelae of injury of cranial nerves	0.005	0.995	0.000
T91.3 Sequelae of injury of spinal cord	0.005	0.995	0.000
J91 Pleural effusion in conditions classified elsewhere	0.000	0.995	0.005
T98 Sequelae of other and unspecified effects of external causes	0.004	0.995	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.004	0.995	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.005	0.995	0.000
H53.0 Amblyopia ex anopsia	0.000	0.995	0.005
T90.5 Sequelae of intracranial injury	0.004	0.995	0.000
T93 Sequelae of injuries of lower limb	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.004	0.995	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.004	0.995	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.004	0.996	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.004	0.996	0.000
T90.1 Sequelae of open wound of head	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.004	0.996	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.004	0.996	0.000
H53.4 Visual field defects	0.000	0.996	0.004
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
T90.4 Sequelae of injury of eye and orbit	0.004	0.996	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
I05.1 Rheumatic mitral insufficiency	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.004	0.996	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.004	0.996	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.004	0.996	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.996	0.004
T98.1 Sequelae of other and unspecified effects of external causes	0.004	0.996	0.000
T91.1 Sequelae of fracture of spine	0.004	0.996	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.996	0.004
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
I78.1 Naevus, nonneoplastic	0.000	0.996	0.004
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.996	0.004
C80.9 Malignant neoplasm, unspecified	0.000	0.996	0.004
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.004	0.996	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.000	0.996	0.004
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.004	0.996	0.000
Q25.1 Coarctation of aorta	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.004	0.996	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.004	0.996	0.000
S02 Fracture of skull and facial bones	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.004	0.996	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.996	0.004
G44.2 Tension-type headache	0.000	0.996	0.004
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.003	0.996	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.996	0.004
T93.1 Sequelae of fracture of femur	0.004	0.996	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.003	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.996	0.004
Q25.6 Stenosis of pulmonary artery	0.003	0.996	0.000
S02.5 Fracture of tooth	0.004	0.996	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.003	0.996	0.000
T98.2 Sequelae of certain early complications of trauma	0.003	0.996	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Z39 Postpartum care and examination	0.000	0.996	0.004
T94.0 Sequelae of injuries involving multiple body regions	0.003	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.996	0.000
S02.50 Fracture of tooth (closed)	0.003	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.997	0.000
S02.6 Fracture of mandible	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
G44 Other headache syndromes	0.000	0.997	0.003
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.997	0.003
S02.3 Fracture of orbital floor	0.003	0.997	0.000
T94.1 Sequelae of injuries, not specified by body region	0.003	0.997	0.000
K07.3 Anomalies of tooth position	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
Z13.1 Special screening examination for diabetes mellitus	0.003	0.997	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.997	0.001
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
G44.8 Other specified headache syndromes	0.000	0.997	0.003
G44.1 Vascular headache, not elsewhere classified	0.000	0.997	0.003
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
G44.3 Chronic posttraumatic headache	0.000	0.997	0.003
S02.7 Multiple fractures involving skull and facial bones	0.003	0.997	0.000
D41.0 Kidney	0.003	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.003	0.997	0.000
D41.2 Ureter	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.002	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.003	0.997	0.000
I09 Other rheumatic heart diseases	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
N90.4 Leukoplakia of vulva	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
M11.2 Other chondrocalcinosis	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.002	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.997	0.003
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
S02.31 Fracture of orbital floor (open)	0.002	0.997	0.000
S02.81 Fractures of other skull and facial bones (open)	0.002	0.997	0.000
C80 Malignant neoplasm without specification of site	0.000	0.997	0.003
D41.9 Urinary organ, unspecified	0.002	0.997	0.000
D41.7 Other urinary organs	0.002	0.997	0.000
D41.3 Urethra	0.002	0.997	0.000
G44.0 Cluster headache syndrome	0.000	0.997	0.002
Z39.2 Routine postpartum follow-up	0.000	0.997	0.002
Q27.4 Congenital phlebectasia	0.002	0.997	0.001
Q27.2 Other congenital malformations of renal artery	0.002	0.997	0.001
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.997	0.001
Q27.1 Congenital renal artery stenosis	0.001	0.998	0.001
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.001	0.998	0.001
D41.1 Renal pelvis	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.998	0.001
H53.8 Other visual disturbances	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.998	0.001
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.001	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.000	0.998	0.002
M84.0 Malunion of fracture	0.000	0.998	0.002
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.998	0.002
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.998	0.001
R59.0 Localised enlarged lymph nodes	0.000	0.998	0.002
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
Z03.1 Observation for suspected malignant neoplasm	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.998	0.001
K07.4 Malocclusion, unspecified	0.002	0.998	0.000
Chapter IX Diseases of the circulatory system	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.001	0.998	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.001	0.998	0.001
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.001	0.998	0.001
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
K07.5 Dentofacial functional abnormalities	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.001
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.001
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M85.4 Solitary bone cyst	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
J86.9 Pyothorax without fistula	0.002	0.998	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
K07.2 Anomalies of dental arch relationship	0.002	0.998	0.000
K07.0 Major anomalies of jaw size	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.001
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.998	0.002
M85.46 Solitary bone cyst (Lower leg)	0.000	0.998	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.002
O64.1 Obstructed labour due to breech presentation	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.001
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.998	0.001
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.001
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.001
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.998	0.001
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.998	0.001
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.001
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.001
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.001
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.998	0.002
D40.0 Prostate	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.001
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.998	0.001
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.998	0.001
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.998	0.001
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.998	0.001
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.001
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.998	0.001
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.998	0.001
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.998	0.001
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.998	0.001
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.998	0.001
K07.8 Other dentofacial anomalies	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.001
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.998	0.001
M84.88 Other disorders of continuity of bone (Other)	0.001	0.998	0.001
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.998	0.001
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.998	0.001
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.998	0.001
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.998	0.001
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.998	0.001
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.998	0.001
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.998	0.001
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.001
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M85.9 Disorder of bone density and structure, unspecified	0.000	0.998	0.002
S01.9 Open wound of head, part unspecified	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.001
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.001
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.998	0.001
M84.26 Delayed union of fracture (Lower leg)	0.001	0.998	0.001
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.998	0.001
M84.24 Delayed union of fracture (Hand)	0.001	0.998	0.001
M84.23 Delayed union of fracture (Forearm)	0.001	0.998	0.001
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.998	0.001
I86.4 Gastric varices	0.000	0.998	0.002
K07.9 Dentofacial anomaly, unspecified	0.002	0.998	0.000
J60-J70 Lung diseases due to external agents	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.001
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.001
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.001
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations