TreeWAS – Variant ID: rs2414739

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D64.9 Anaemia, unspecified	0.103	0.897	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.085	0.915	0.000
D64 Other anaemias	0.044	0.956	0.000
D64.8 Other specified anaemias	0.032	0.968	0.000
D64.4 Congenital dyserythropoietic anaemia	0.032	0.968	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.032	0.968	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.032	0.968	0.000
D64.0 Hereditary sideroblastic anaemia	0.030	0.970	0.000
D64.3 Other sideroblastic anaemias	0.030	0.970	0.000
N81.1 Cystocele	0.020	0.980	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985	0.000
D69.6 Thrombocytopenia, unspecified	0.012	0.988	0.000
N02.9 Unspecified	0.012	0.988	0.000
N89 Other noninflammatory disorders of vagina	0.011	0.989	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.990	0.010
D69 Purpura and other haemorrhagic conditions	0.010	0.990	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.009	0.991	0.000
D69.4 Other primary thrombocytopenia	0.009	0.991	0.000
N89.3 Dysplasia of vagina, unspecified	0.009	0.991	0.000
N89.7 Haematocolpos	0.008	0.992	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.008	0.992	0.000
N89.0 Mild vaginal dysplasia	0.008	0.992	0.000
N89.4 Leukoplakia of vagina	0.008	0.992	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.008	0.992	0.000
K90.0 Coeliac disease	0.008	0.992	0.000
D60-D64 Aplastic and other anaemias	0.008	0.992	0.000
S82.60 Fracture of lateral malleolus (closed)	0.008	0.992	0.000
D69.1 Qualitative platelet defects	0.008	0.992	0.000
D69.8 Other specified haemorrhagic conditions	0.007	0.993	0.000
N89.1 Moderate vaginal dysplasia	0.007	0.993	0.000
K55.2 Angiodysplasia of colon	0.007	0.993	0.000
Z52.4 Kidney donor	0.000	0.993	0.007
D69.9 Haemorrhagic condition, unspecified	0.007	0.993	0.000
N89.5 Stricture and atresia of vagina	0.007	0.993	0.000
D69.2 Other nonthrombocytopenic purpura	0.007	0.993	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.993	0.007
N89.6 Tight hymenal ring	0.007	0.993	0.000
S06.5 Traumatic subdural haemorrhage	0.007	0.993	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
D69.5 Secondary thrombocytopenia	0.006	0.994	0.000
M23.3 Other meniscus derangements	0.006	0.994	0.000
D69.0 Allergic purpura	0.006	0.994	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.006	0.994	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.006	0.994	0.000
N02 Recurrent and persistent haematuria	0.006	0.994	0.000
K12.1 Other forms of stomatitis	0.006	0.994	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.006	0.994	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.005	0.994	0.000
N43.3 Hydrocele, unspecified	0.006	0.994	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.005	0.995	0.000
Z52 Donors of organs and tissues	0.000	0.995	0.005
D62 Acute posthaemorrhagic anaemia	0.005	0.995	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.005	0.995	0.000
S06.2 Diffuse brain injury	0.005	0.995	0.000
S06 Intracranial injury	0.005	0.995	0.000
N02.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.995	0.005
F17.2 Dependence syndrome	0.005	0.995	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.995	0.005
Z52.3 Bone marrow donor	0.000	0.995	0.005
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
N02.0 Minor glomerular abnormality	0.005	0.995	0.000
R60.0 Localised oedema	0.005	0.995	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.995	0.005
Z52.0 Blood donor	0.000	0.995	0.005
N02.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
R60.9 Oedema, unspecified	0.005	0.995	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.005	0.995	0.000
M23.37 Other meniscus derangements-Capsular lig	0.005	0.995	0.000
Z52.8 Donor of other organs and tissues	0.000	0.995	0.005
Y42.9 Other and unspecified hormone antagonists	0.000	0.995	0.005
D60.8 Other acquired pure red cell aplasias	0.004	0.995	0.000
D60.1 Transient acquired pure red cell aplasia	0.004	0.995	0.000
D60.0 Chronic acquired pure red cell aplasia	0.004	0.995	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.004	0.995	0.000
N02.6 Dense deposit disease	0.004	0.995	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.995	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.995	0.000
R60 Oedema, not elsewhere classified	0.005	0.995	0.000
S06.4 Epidural haemorrhage	0.004	0.995	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.995	0.000
R60.1 Generalised oedema	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
S06.9 Intracranial injury, unspecified	0.004	0.996	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
Z52.9 Donor of unspecified organ or tissue	0.000	0.996	0.004
Z52.7 Heart donor	0.000	0.996	0.004
Z52.6 Liver donor	0.000	0.996	0.004
Z52.5 Cornea donor	0.000	0.996	0.004
Z52.1 Skin donor	0.000	0.996	0.004
S06.3 Focal brain injury	0.004	0.996	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.996	0.004
S06.40 Epidural haemorrhage (without open intracranial wound)	0.004	0.996	0.000
Y42.4 Oral contraceptives	0.000	0.996	0.004
S06.21 Diffuse brain injury (with open intracranial wound)	0.004	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
S06.1 Traumatic cerebral oedema	0.004	0.996	0.000
S06.7 Intracranial injury with prolonged coma	0.004	0.996	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
G83.2 Monoplegia of upper limb	0.000	0.996	0.004
S82.6 Fracture of lateral malleolus	0.004	0.996	0.000
Y42.2 Antithyroid drugs	0.000	0.996	0.004
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.004	0.996	0.000
Z52.2 Bone donor	0.000	0.996	0.004
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.004	0.996	0.000
G83 Other paralytic syndromes	0.000	0.996	0.004
G83.1 Monoplegia of lower limb	0.000	0.996	0.004
G83.9 Paralytic syndrome, unspecified	0.000	0.996	0.004
M23.30 Other meniscus derangements (Multiple sites)	0.004	0.996	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.996	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.997	0.003
I35.0 Aortic (valve) stenosis	0.003	0.997	0.000
D61 Other aplastic anaemias	0.003	0.997	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.003	0.997	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.003	0.997	0.000
S82.61 Fracture of lateral malleolus (open)	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
S06.0 Concussion	0.003	0.997	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.997	0.003
S06.31 Focal brain injury (with open intracranial wound)	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.997	0.003
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.997	0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.003	0.997	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.003	0.997	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.997	0.003
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.003	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.997	0.003
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
G83.5 Locked-in syndrome	0.000	0.997	0.003
G83.3 Monoplegia, unspecified	0.000	0.997	0.003
G83.0 Diplegia of upper limbs	0.000	0.997	0.003
D63 Anaemia in chronic diseases classified elsewhere	0.003	0.997	0.000
G83.8 Other specified paralytic syndromes	0.000	0.997	0.003
S51.8 Open wound of other parts of forearm	0.000	0.997	0.003
H90.3 Sensorineural hearing loss, bilateral	0.000	0.997	0.003
N76.4 Abscess of vulva	0.000	0.997	0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
M48.09 Spinal stenosis (Site unspecified)	0.000	0.997	0.003
D61.8 Other specified aplastic anaemias	0.003	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.003	0.997	0.000
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.997	0.003
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.997	0.003
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.997	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
G83.4 Cauda equina syndrome	0.000	0.997	0.003
O67.9 Intrapartum haemorrhage, unspecified	0.003	0.997	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.003	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.997	0.000
M05.0 Felty's syndrome	0.002	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.997	0.000
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.997	0.000
D35.2 Pituitary gland	0.000	0.997	0.003
M05.8 Other seropositive rheumatoid arthritis	0.002	0.997	0.000
M48.0 Spinal stenosis	0.000	0.997	0.003
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.997	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.000	0.997	0.003
Z94.7 Corneal transplant status	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.997	0.003
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
M05.28 Rheumatoid vasculitis (Other)	0.002	0.998	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.998	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.998	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.998	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.998	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.998	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.998	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
M05.18 Rheumatoid lung disease (Other)	0.002	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
N02.8 Other	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.998	0.002
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.998	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.998	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.998	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.998	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.998	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.998	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.998	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.998	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.998	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.998	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
M48 Other spondylopathies	0.000	0.998	0.002
M05.08 Felty's syndrome (Other)	0.002	0.998	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.998	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.998	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.998	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.998	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.998	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.998	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.998	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.998	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.998	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.998	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.002
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
J35.0 Chronic tonsillitis	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.998	0.002
M05.09 Felty's syndrome (Site unspecified)	0.002	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.002
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.002	0.998	0.000
I35.8 Other aortic valve disorders	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
S51 Open wound of forearm	0.000	0.998	0.002
L73.9 Follicular disorder, unspecified	0.002	0.998	0.000
M48.8 Other specified spondylopathies	0.000	0.998	0.002
W08.0 Home	0.002	0.998	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.002	0.998	0.000
M48.9 Spondylopathy, unspecified	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
A46 Erysipelas	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.998	0.002
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.998	0.002
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.998	0.002
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.002
F43.0 Acute stress reaction	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.000	0.998	0.002
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.002	0.998	0.000
S51.7 Multiple open wounds of forearm	0.000	0.998	0.002
M23.6 Other spontaneous disruption of ligament(s) of knee	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
M48.4 Fatigue fracture of vertebra	0.000	0.998	0.002
M48.3 Traumatic spondylopathy	0.000	0.998	0.002
M48.2 Kissing spine	0.000	0.998	0.002
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.998	0.002
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
K12 Stomatitis and related lesions	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
D57 Sickle-cell disorders	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.000	0.998	0.002
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.998	0.002
N00-N08 Glomerular diseases	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.998	0.002
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.000	0.998	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
K55 Vascular disorders of intestine	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.000	0.998	0.002
D56 Thalassaemia	0.002	0.998	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
N43.1 Infected hydrocele	0.002	0.998	0.000
I35 Nonrheumatic aortic valve disorders	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.998	0.001
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.998	0.001
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.998	0.001
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.998	0.001
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.998	0.001
G80.8 Other infantile cerebral palsy	0.000	0.998	0.002
M17.3 Other posttraumatic gonarthrosis	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
N04 Nephrotic syndrome	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.998	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.002	0.998	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.001
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.001
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.001
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.001
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.001
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.001
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
N04.9 Unspecified	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.002	0.998	0.000
R23.1 Pallor	0.002	0.998	0.000
K90 Intestinal malabsorption	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.998	0.000
G80.1 Spastic diplegia	0.000	0.998	0.001
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
Q52.5 Fusion of labia	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
N00 Acute nephritic syndrome	0.002	0.998	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.001	0.998	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.001	0.998	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.001	0.998	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.001	0.998	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.998	0.001
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.998	0.001
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.998	0.001
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.998	0.001
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.998	0.001
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.998	0.001
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.998	0.001
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.998	0.001
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.998	0.001
M48.29 Kissing spine (Site unspecified)	0.000	0.998	0.001
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.27 Kissing spine (Lumbosacral region)	0.000	0.998	0.001
M48.26 Kissing spine (Lumbar region)	0.000	0.998	0.001
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.998	0.001
M48.24 Kissing spine (Thoracic region)	0.000	0.998	0.001
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.998	0.001
M48.22 Kissing spine (Cervical region)	0.000	0.998	0.001
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.998	0.001
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.998	0.001
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.998	0.001
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.998	0.001
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.998	0.001
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.998	0.001
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.998	0.001
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.998	0.001
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.998	0.001
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.998	0.001
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.998	0.001
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.998	0.001
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.998	0.001
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.998	0.001
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.998	0.001
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.998	0.001
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.998	0.001
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.998	0.001
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.998	0.001
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.998	0.001
A49.9 Bacterial infection, unspecified	0.000	0.998	0.002
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
M48.99 Spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.001
D57.8 Other sickle-cell disorders	0.001	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.000	0.998	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.001
I65.0 Occlusion and stenosis of vertebral artery	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.998	0.002
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.001	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
M23 Internal derangement of knee	0.002	0.998	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.001	0.998	0.000
N06 Isolated proteinuria with specified morphological lesion	0.001	0.998	0.000
N01 Rapidly progressive nephritic syndrome	0.001	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.001
G80.2 Infantile hemiplegia	0.000	0.998	0.001
Y46.4 Iminostilbenes	0.000	0.998	0.002
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.998	0.002
D56.8 Other thalassaemias	0.001	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.998	0.000
D56.3 Thalassaemia trait	0.001	0.998	0.000
D56.2 Delta-beta thalassaemia	0.001	0.998	0.000
D56.0 Alpha thalassaemia	0.001	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.998	0.000
N05.9 Unspecified	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.001
D56.9 Thalassaemia, unspecified	0.001	0.998	0.000
N04.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
M47.2 Other spondylosis with radiculopathy	0.000	0.998	0.001
N43.4 Spermatocele	0.001	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.001	0.998	0.000
N43.2 Other hydrocele	0.001	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.998	0.001
Y54.5 Other diuretics	0.000	0.998	0.001
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.999	0.001
M23.5 Chronic instability of knee	0.001	0.999	0.000
N00.9 Unspecified	0.001	0.999	0.000
N04.8 Other	0.001	0.999	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N04.6 Dense deposit disease	0.001	0.999	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.000	0.999	0.001
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.999	0.001
F12.1 Harmful use	0.001	0.999	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.999	0.000
M23.4 Loose body in knee	0.001	0.999	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.999	0.001
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
Y52.1 Calcium-channel blockers	0.000	0.999	0.001
Z29.2 Other prophylactic chemotherapy	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations