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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2442736
log Bayes Factor = 293.119
Chromosome 6   position 31,346,621  (GRCh37) Explore rs2442736 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
B35-B49 Mycoses
1.000 0.000 0.000
B37 Candidiasis
1.000 0.000 0.000
C83 Diffuse non-Hodgkin's lymphoma
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
D86 Sarcoidosis
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
N00-N08 Glomerular diseases
0.999 0.001 0.000
C83.3 Large cell (diffuse)
0.999 0.001 0.000
K75.4 Autoimmune hepatitis
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.998 0.002 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.997 0.003 0.000
N17-N19 Renal failure
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.996 0.004 0.000
B37.9 Candidiasis, unspecified
0.995 0.005 0.000
D86.9 Sarcoidosis, unspecified
0.993 0.007 0.000
H36.0 Diabetic retinopathy
0.992 0.008 0.000
E10.1 With ketoacidosis
0.992 0.008 0.000
D70 Agranulocytosis
0.992 0.008 0.000
E11.3 With ophthalmic complications
0.989 0.011 0.000
K72 Hepatic failure, not elsewhere classified
0.989 0.011 0.000
E14.3 With ophthalmic complications
0.989 0.011 0.000
N04 Nephrotic syndrome
0.988 0.012 0.000
H36 Retinal disorders in diseases classified elsewhere
0.986 0.014 0.000
N18 Chronic renal failure
0.986 0.014 0.000
N10-N16 Renal tubulo-interstitial diseases
0.984 0.016 0.000
H30-H36 Disorders of choroid and retina
0.982 0.018 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.981 0.019 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.980 0.020 0.000
K74 Fibrosis and cirrhosis of liver
0.980 0.020 0.000
N17 Acute renal failure
0.979 0.021 0.000
M60-M63 Disorders of muscles
0.978 0.022 0.000
M05-M14 Inflammatory polyarthropathies
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
M07 Psoriatic and enteropathic arthropathies
0.976 0.024 0.000
M07.3 Other psoriatic arthropathies
0.976 0.024 0.000
K73 Chronic hepatitis, not elsewhere classified
0.975 0.025 0.000
K75.8 Other specified inflammatory liver diseases
0.975 0.025 0.000
M15-M19 Arthrosis
0.973 0.027 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.972 0.028 0.000
B37.0 Candidal stomatitis
0.971 0.029 0.000
M20.1 Hallux valgus (acquired)
0.000 0.030 0.970
B37.8 Candidiasis of other sites
0.970 0.030 0.000
C85.1 B-cell lymphoma, unspecified
0.969 0.031 0.000
M17 Gonarthrosis [arthrosis of knee]
0.969 0.031 0.000
K72.9 Hepatic failure, unspecified
0.967 0.033 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.967 0.033 0.000
N17.9 Acute renal failure, unspecified
0.967 0.033 0.000
M17.1 Other primary gonarthrosis
0.966 0.034 0.000
N04.9 Unspecified
0.965 0.035 0.000
N13 Obstructive and reflux uropathy
0.963 0.037 0.000
K70 Alcoholic liver disease
0.963 0.037 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.962 0.038 0.000
E10.2 With renal complications
0.960 0.040 0.000
Chapter II Neoplasms
0.959 0.041 0.000
B15-B19 Viral hepatitis
0.956 0.044 0.000
M20 Acquired deformities of fingers and toes
0.000 0.044 0.956
K52.8 Other specified non-infective gastro-enteritis and colitis
0.955 0.045 0.000
N18.9 Chronic renal failure, unspecified
0.954 0.046 0.000
K50-K52 Noninfective enteritis and colitis
0.947 0.047 0.007
M07.39 Other psoriatic arthropathies (Site unspecified)
0.953 0.047 0.000
E06 Thyroiditis
0.952 0.048 0.000
N05 Unspecified nephritic syndrome
0.951 0.049 0.000
N11 Chronic tubulo-interstitial nephritis
0.951 0.049 0.000
L10-L14 Bullous disorders
0.950 0.049 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.950 0.050 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.949 0.051 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.949 0.051 0.000
D55-D59 Haemolytic anaemias
0.948 0.052 0.000
K52 Other non-infective gastro-enteritis and colitis
0.945 0.054 0.001
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.945 0.055 0.000
K74.6 Other and unspecified cirrhosis of liver
0.944 0.056 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.058 0.942
E14.9 Without complications
0.942 0.058 0.000
D73 Diseases of spleen
0.942 0.058 0.000
M62 Other disorders of muscle
0.939 0.061 0.000
D86.3 Sarcoidosis of skin
0.938 0.062 0.000
K70.9 Alcoholic liver disease, unspecified
0.938 0.062 0.000
Chapter VI Diseases of the nervous system
0.937 0.063 0.000
A63.0 Anogenital (venereal) warts
0.937 0.063 0.000
B18 Chronic viral hepatitis
0.934 0.066 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.934 0.066 0.000
L20-L30 Dermatitis and eczema
0.932 0.068 0.000
L50-L54 Urticaria and erythema
0.930 0.070 0.000
B00 Herpesviral [herpes simplex] infections
0.929 0.071 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.929 0.071 0.000
E11.1 With ketoacidosis
0.929 0.071 0.000
E06.3 Autoimmune thyroiditis
0.925 0.075 0.000
E11.9 Without complications
0.924 0.076 0.000
C81 Hodgkin's disease
0.923 0.077 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.919 0.081 0.000
M32 Systemic lupus erythematosus
0.918 0.082 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.918 0.082 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.915 0.085 0.000
H46 Optic neuritis
0.915 0.085 0.000
H30 Chorioretinal inflammation
0.912 0.088 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.912 0.088 0.000
M34 Systemic sclerosis
0.911 0.089 0.000
K76 Other diseases of liver
0.911 0.089 0.000
E10.8 With unspecified complications
0.911 0.089 0.000
D80 Immunodeficiency with predominantly antibody defects
0.911 0.089 0.000
D61 Other aplastic anaemias
0.908 0.092 0.000
B18.2 Chronic viral hepatitis C
0.905 0.095 0.000
L13 Other bullous disorders
0.905 0.095 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.903 0.097 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.900 0.100 0.000
D59 Acquired haemolytic anaemia
0.900 0.100 0.000
M62.8 Other specified disorders of muscle
0.899 0.101 0.000
E10.4 With neurological complications
0.898 0.102 0.000
D69 Purpura and other haemorrhagic conditions
0.898 0.102 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.893 0.107 0.000
C34 Malignant neoplasm of bronchus and lung
0.893 0.107 0.000
B02 Zoster [herpes zoster]
0.893 0.107 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.109 0.891
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.891 0.109 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.890 0.110 0.000
L94 Other localised connective tissue disorders
0.888 0.112 0.000
L28 Lichen simplex chronicus and prurigo
0.884 0.116 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.884 0.116 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.884 0.116 0.000
M17.0 Primary gonarthrosis, bilateral
0.881 0.119 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.120 0.880
E24 Cushing's syndrome
0.879 0.121 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.877 0.123 0.000
D62 Acute posthaemorrhagic anaemia
0.875 0.125 0.000
E21.3 Hyperparathyroidism, unspecified
0.872 0.128 0.000
G62 Other polyneuropathies
0.872 0.128 0.000
L13.0 Dermatitis herpetiformis
0.872 0.128 0.000
C83.0 Small cell (diffuse)
0.871 0.129 0.000
C04 Malignant neoplasm of floor of mouth
0.871 0.129 0.000
K90.9 Intestinal malabsorption, unspecified
0.871 0.129 0.000
D86.8 Sarcoidosis of other and combined sites
0.871 0.129 0.000
L27 Dermatitis due to substances taken internally
0.870 0.130 0.000
M60 Myositis
0.869 0.131 0.000
D68 Other coagulation defects
0.869 0.131 0.000
N05.2 Diffuse membranous glomerulonephritis
0.868 0.132 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.868 0.132 0.000
G62.9 Polyneuropathy, unspecified
0.867 0.133 0.000
C91 Lymphoid leukaemia
0.866 0.134 0.000
K74.0 Hepatic fibrosis
0.865 0.134 0.000
M21 Other acquired deformities of limbs
0.865 0.135 0.000
N18.3 Chronic kidney disease, stage 3
0.864 0.136 0.000
K76.9 Liver disease, unspecified
0.862 0.138 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.139 0.861
E16.0 Drug-induced hypoglycaemia without coma
0.860 0.140 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.860 0.140 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.858 0.142 0.000
D86.0 Sarcoidosis of lung
0.857 0.143 0.000
M91-M94 Chondropathies
0.855 0.145 0.000
K73.9 Chronic hepatitis, unspecified
0.854 0.146 0.000
C34.3 Lower lobe, bronchus or lung
0.854 0.146 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.854 0.146 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.853 0.147 0.000
G51 Facial nerve disorders
0.852 0.148 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.851 0.149 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.851 0.149 0.000
C02.9 Tongue, unspecified
0.849 0.151 0.000
L52 Erythema nodosum
0.847 0.153 0.000
H47.3 Other disorders of optic disk
0.847 0.153 0.000
N18.4 Chronic kidney disease, stage 4
0.846 0.154 0.000
B00.9 Herpesviral infection, unspecified
0.844 0.156 0.000
B02.9 Zoster without complication
0.844 0.156 0.000
E14.8 With unspecified complications
0.842 0.158 0.000
R63.4 Abnormal weight loss
0.842 0.158 0.000
D86.1 Sarcoidosis of lymph nodes
0.841 0.159 0.000
M24 Other specific joint derangements
0.840 0.160 0.000
G30-G32 Other degenerative diseases of the nervous system
0.840 0.160 0.000
M33 Dermatopolymyositis
0.839 0.161 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.838 0.162 0.000
K72.0 Acute and subacute hepatic failure
0.837 0.163 0.000
H30.9 Chorioretinal inflammation, unspecified
0.832 0.168 0.000
M31 Other necrotising vasculopathies
0.831 0.169 0.000
L92.0 Granuloma annulare
0.830 0.170 0.000
G56 Mononeuropathies of upper limb
0.830 0.170 0.000
D61.9 Aplastic anaemia, unspecified
0.830 0.170 0.000
D73.0 Hyposplenism
0.829 0.171 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.827 0.173 0.000
C34.0 Main bronchus
0.825 0.175 0.000
M17.5 Other secondary gonarthrosis
0.825 0.175 0.000
E03.8 Other specified hypothyroidism
0.824 0.176 0.000
G56.0 Carpal tunnel syndrome
0.821 0.179 0.000
L40.1 Generalised pustular psoriasis
0.820 0.180 0.000
N05.1 Focal and segmental glomerular lesions
0.820 0.180 0.000
M15 Polyarthrosis
0.820 0.180 0.000
C84.5 Other and unspecified T-cell lymphomas
0.819 0.181 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.819 0.181 0.000
H34 Retinal vascular occlusions
0.817 0.183 0.000
D68.0 Von Willebrand's disease
0.817 0.183 0.000
B36 Other superficial mycoses
0.817 0.183 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.817 0.183 0.000
M86-M90 Other osteopathies
0.813 0.187 0.000
A15-A19 Tuberculosis
0.812 0.188 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.810 0.190 0.000
B37.7 Candidal septicaemia
0.810 0.190 0.000
L94.2 Calcinosis cutis
0.810 0.190 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.809 0.191 0.000
M35.7 Hypermobility syndrome
0.809 0.191 0.000
C13 Malignant neoplasm of hypopharynx
0.809 0.191 0.000
E10.7 With multiple complications
0.808 0.192 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.807 0.193 0.000
D59.1 Other autoimmune haemolytic anaemias
0.805 0.195 0.000
G51.9 Disorder of facial nerve, unspecified
0.804 0.196 0.000
L28.0 Lichen simplex chronicus
0.804 0.196 0.000
L40.0 Psoriasis vulgaris
0.804 0.196 0.000
K72.1 Chronic hepatic failure
0.804 0.196 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.803 0.197 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.803 0.197 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.802 0.198 0.000
N04.2 Diffuse membranous glomerulonephritis
0.801 0.198 0.000
L44 Other papulosquamous disorders
0.800 0.200 0.000
N04.1 Focal and segmental glomerular lesions
0.800 0.200 0.000
D69.4 Other primary thrombocytopenia
0.800 0.200 0.000
C81.1 Nodular sclerosis
0.800 0.200 0.000
C88 Malignant immunoproliferative diseases
0.797 0.203 0.000
N18.0 End-stage renal disease
0.795 0.205 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.794 0.206 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.794 0.206 0.000
D69.2 Other nonthrombocytopenic purpura
0.794 0.206 0.000
D64.8 Other specified anaemias
0.793 0.207 0.000
E25 Adrenogenital disorders
0.792 0.208 0.000
K71 Toxic liver disease
0.791 0.209 0.000
D69.6 Thrombocytopenia, unspecified
0.788 0.212 0.000
N13.8 Other obstructive and reflux uropathy
0.788 0.212 0.000
C04.9 Floor of mouth, unspecified
0.787 0.213 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.786 0.214 0.000
N18.1 Chronic kidney disease, stage 1
0.786 0.214 0.000
D73.9 Disease of spleen, unspecified
0.785 0.215 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.785 0.215 0.000
N03 Chronic nephritic syndrome
0.783 0.217 0.000
N11.1 Chronic obstructive pyelonephritis
0.782 0.218 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.782 0.218 0.000
L94.0 Localised scleroderma [morphea]
0.781 0.219 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.781 0.219 0.000
E26 Hyperaldosteronism
0.781 0.219 0.000
M34.0 Progressive systemic sclerosis
0.780 0.220 0.000
E31 Polyglandular dysfunction
0.780 0.220 0.000
M60.9 Myositis, unspecified
0.780 0.220 0.000
B00.5 Herpesviral ocular disease
0.779 0.221 0.000
Chapter XX External causes of morbidity and mortality
0.779 0.221 0.000
L28.1 Prurigo nodularis
0.779 0.221 0.000
E11.2 With renal complications
0.776 0.224 0.000
H35 Other retinal disorders
0.776 0.224 0.000
B07 Viral warts
0.776 0.224 0.000
A20-A28 Certain zoonotic bacterial diseases
0.774 0.226 0.000
B37.2 Candidiasis of skin and nail
0.774 0.226 0.000
K76.6 Portal hypertension
0.774 0.226 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.774 0.226 0.000
C83.1 Small cleaved cell (diffuse)
0.772 0.228 0.000
B25-B34 Other viral diseases
0.772 0.228 0.000
E14.2 Withrenal complications
0.772 0.228 0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
0.772 0.228 0.000
D73.5 Infarction of spleen
0.771 0.229 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.230 0.770
D84 Other immunodeficiencies
0.768 0.232 0.000
E11.5 With peripheral circulatory complications
0.768 0.232 0.000
E24.0 Pituitary-dependent Cushing's disease
0.768 0.232 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.768 0.232 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.768 0.232 0.000
E50-E64 Other nutritional deficiencies
0.768 0.232 0.000
E27.9 Disorder of adrenal gland, unspecified
0.768 0.232 0.000
E07 Other disorders of thyroid
0.768 0.232 0.000
G31.8 Other specified degenerative diseases of nervous system
0.764 0.236 0.000
B44 Aspergillosis
0.764 0.236 0.000
M11 Other crystal arthropathies
0.763 0.237 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.763 0.237 0.000
N04.0 Minor glomerular abnormality
0.762 0.238 0.000
N13.6 Pyonephrosis
0.760 0.240 0.000
K90.8 Other intestinal malabsorption
0.759 0.241 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.759 0.241 0.000
K70.0 Alcoholic fatty liver
0.758 0.242 0.000
L53 Other erythematous conditions
0.758 0.242 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.758 0.242 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.758 0.242 0.000
E14.1 With ketoacidosis
0.757 0.243 0.000
L80 Vitiligo
0.755 0.245 0.000
M21.0 Valgus deformity, not elsewhere classified
0.752 0.248 0.000
H30.2 Posterior cyclitis
0.752 0.248 0.000
M21.8 Other specified acquired deformities of limbs
0.751 0.249 0.000
E24.2 Drug-induced Cushing's syndrome
0.750 0.250 0.000
M18 Arthrosis of first carpometacarpal joint
0.750 0.250 0.000
C91.1 Chronic lymphocytic leukaemia
0.750 0.250 0.000
L12 Pemphigoid
0.749 0.250 0.000
D83 Common variable immunodeficiency
0.749 0.251 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.749 0.251 0.000
G51.3 Clonic hemifacial spasm
0.749 0.251 0.000
C07 Malignant neoplasm of parotid gland
0.749 0.251 0.000
C91.9 Lymphoid leukaemia, unspecified
0.749 0.251 0.000
N15 Other renal tubulo-interstitial diseases
0.747 0.253 0.000
L40.3 Pustulosis palmaris et plantaris
0.744 0.256 0.000
L93 Lupus erythematosus
0.742 0.258 0.000
N13.4 Hydroureter
0.741 0.259 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.740 0.260 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.740 0.260 0.000
D56 Thalassaemia
0.739 0.261 0.000
H47.2 Optic atrophy
0.739 0.261 0.000
M33.1 Other dermatomyositis
0.738 0.262 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.738 0.262 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.738 0.262 0.000
M34.1 CR(E)ST syndrome
0.738 0.262 0.000
D68.9 Coagulation defect, unspecified
0.735 0.265 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.735 0.265 0.000
C83.7 Burkitt's tumour
0.733 0.267 0.000
E11.0 With coma
0.732 0.268 0.000
B01 Varicella [chickenpox]
0.732 0.268 0.000
B37.1 Pulmonary candidiasis
0.732 0.268 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.731 0.269 0.000
E20 Hypoparathyroidism
0.731 0.269 0.000
E34 Other endocrine disorders
0.729 0.270 0.000
M35.2 Behcet's disease
0.729 0.271 0.000
N25-N29 Other disorders of kidney and ureter
0.729 0.271 0.000
D72 Other disorders of white blood cells
0.728 0.272 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.728 0.272 0.000
K76.7 Hepatorenal syndrome
0.727 0.273 0.000
K75.9 Inflammatory liver disease, unspecified
0.726 0.274 0.000
C81.2 Mixed cellularity
0.725 0.275 0.000
C81.0 Lymphocytic predominance
0.723 0.277 0.000
E28 Ovarian dysfunction
0.723 0.277 0.000
C81.9 Hodgkin's disease, unspecified
0.722 0.278 0.000
C10 Malignant neoplasm of oropharynx
0.721 0.279 0.000
L23 Allergic contact dermatitis
0.719 0.281 0.000
K74.5 Biliary cirrhosis, unspecified
0.719 0.281 0.000
N17.0 Acute renal failure with tubular necrosis
0.719 0.281 0.000
C38.4 Pleura
0.718 0.282 0.000
B37.4 Candidiasis of other urogenital sites
0.718 0.282 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C85.0 Lymphosarcoma
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
D82 Immunodeficiency associated with other major defects
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
B37.6 Candidal endocarditis
0.717 0.283 0.000
B37.5 Candidal meningitis
0.717 0.283 0.000
B48 Other mycoses, not elsewhere classified
0.717 0.283 0.000
B47 Mycetoma
0.717 0.283 0.000
B46 Zygomycosis
0.717 0.283 0.000
B45 Cryptococcosis
0.717 0.283 0.000
B43 Chromomycosis and phaeomycotic abscess
0.717 0.283 0.000
B42 Sporotrichosis
0.717 0.283 0.000
B41 Paracoccidioidomycosis
0.717 0.283 0.000
B40 Blastomycosis
0.717 0.283 0.000
B39 Histoplasmosis
0.717 0.283 0.000
B38 Coccidioidomycosis
0.717 0.283 0.000
M10 Gout
0.717 0.283 0.000
C83.6 Undifferentiated (diffuse)
0.717 0.283 0.000
C83.5 Lymphoblastic (diffuse)
0.717 0.283 0.000
C83.4 Immunoblastic (diffuse)
0.717 0.283 0.000
C83.2 Mixed small and large cell (diffuse)
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E14.5 With peripheral circulatory complications
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
N00 Acute nephritic syndrome
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
E10.6 With other specified complications
0.716 0.284 0.000
E14.7 With multiple complications
0.716 0.284 0.000
E14.0 With coma
0.716 0.284 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
M93 Other osteochondropathies
0.716 0.284 0.000
D74 Methaemoglobinaemia
0.715 0.285 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.715 0.285 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.715 0.285 0.000
C04.0 Anterior floor of mouth
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.715 0.285 0.000
B17 Other acute viral hepatitis
0.714 0.286 0.000
D61.1 Drug-induced aplastic anaemia
0.714 0.286 0.000
L27.2 Dermatitis due to ingested food
0.713 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.711 0.289 0.000
L50 Urticaria
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
N04.8 Other
0.708 0.292 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.708 0.292 0.000
N04.6 Dense deposit disease
0.708 0.292 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.708 0.292 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.708 0.292 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.708 0.292 0.000
H35.0 Background retinopathy and retinal vascular changes
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
C34.9 Bronchus or lung, unspecified
0.708 0.292 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.708 0.292 0.000
N18.5 Chronic kidney disease, stage 5
0.707 0.293 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.707 0.293 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
M34.9 Systemic sclerosis, unspecified
0.706 0.294 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.705 0.295 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.704 0.296 0.000
B06 Rubella [German measles]
0.704 0.296 0.000
B05 Measles
0.704 0.296 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.704 0.296 0.000
B04 Monkeypox
0.704 0.296 0.000
B03 Smallpox
0.704 0.296 0.000
M86 Osteomyelitis
0.704 0.296 0.000
D73.4 Cyst of spleen
0.703 0.297 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.703 0.297 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.702 0.297 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.702 0.297 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.702 0.297 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.702 0.297 0.000
K74.4 Secondary biliary cirrhosis
0.702 0.297 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.702 0.297 0.000
K74.1 Hepatic sclerosis
0.702 0.297 0.000
N17.2 Acute renal failure with medullary necrosis
0.702 0.298 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.702 0.298 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.701 0.298 0.000
M61 Calcification and ossification of muscle
0.701 0.298 0.000
D66 Hereditary factor VIII deficiency
0.701 0.299 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.701 0.299 0.000
M08 Juvenile arthritis
0.701 0.299 0.000
B02.2 Zoster with other nervous system involvement
0.700 0.300 0.000
M07.6 Other enteropathic arthropathies
0.700 0.300 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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