TreeWAS – Variant ID: rs2479768

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	No effect posterior probability	Protective posterior probability
Chapter XV Pregnancy, childbirth and the puerperium	0.383	0.617
O60-O75 Complications of labour and delivery	0.407	0.593
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.417	0.583
O00-O08 Pregnancy with abortive outcome	0.420	0.580
O80-O84 Delivery	0.426	0.574
O94-O99 Other obstetric conditions, not elsewhere classified	0.435	0.565
O20-O29 Other maternal disorders predominantly related to pregnancy	0.436	0.564
O36 Maternal care for other known or suspected foetal problems	0.446	0.554
O02 Other abnormal products of conception	0.467	0.533
O70 Perineal laceration during delivery	0.468	0.532
O85-O92 Complications predominantly related to the puerperium	0.469	0.531
O68 Labour and delivery complicated by foetal stress [distress]	0.470	0.530
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.470	0.530
O82 Single delivery by Caesarean section	0.483	0.517
O34 Maternal care for known or suspected abnormality of pelvic organs	0.492	0.508
O63 Long labour	0.495	0.505
O26 Maternal care for other conditions predominantly related to pregnancy	0.499	0.501
O62 Abnormalities of forces of labour	0.502	0.498
O02.1 Missed abortion	0.503	0.497
O80 Single spontaneous delivery	0.509	0.491
O70.1 Second degree perineal laceration during delivery	0.511	0.489
O36.5 Maternal care for poor foetal growth	0.512	0.488
O20 Haemorrhage in early pregnancy	0.516	0.484
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.517	0.483
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.519	0.481
O03 Spontaneous abortion	0.524	0.476
O36.9 Maternal care for foetal problem, unspecified	0.525	0.475
O36.6 Maternal care for excessive foetal growth	0.546	0.454
O00 Ectopic pregnancy	0.547	0.453
O43 Placental disorders	0.548	0.452
O82.1 Delivery by emergency Caesarean section	0.551	0.449
O61 Failed induction of labour	0.553	0.447
O44 Placenta praevia	0.553	0.447
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.556	0.444
O70.2 Third degree perineal laceration during delivery	0.559	0.441
O75 Other complications of labour and delivery, not elsewhere classified	0.561	0.439
O80.0 Spontaneous vertex delivery	0.562	0.438
O20.9 Haemorrhage in early pregnancy, unspecified	0.564	0.436
O40 Polyhydramnios	0.566	0.433
O32 Maternal care for known or suspected malpresentation of foetus	0.570	0.430
O26.8 Other specified pregnancy-related conditions	0.570	0.430
O86 Other puerperal infections	0.571	0.429
O82.0 Delivery by elective Caesarean section	0.571	0.429
O73 Retained placenta and membranes, without haemorrhage	0.571	0.429
O34.2 Maternal care due to uterine scar from previous surgery	0.573	0.427
O45 Premature separation of placenta [abruptio placentae]	0.575	0.425
O60 Preterm delivery	0.575	0.425
O46 Antepartum haemorrhage, not elsewhere classified	0.577	0.422
O01 Hydatidiform mole	0.578	0.422
O63.0 Prolonged first stage (of labour)	0.579	0.421
O06 Unspecified abortion	0.579	0.421
O84 Multiple delivery	0.579	0.420
O36.0 Maternal care for rhesus isoimmunisation	0.580	0.420
O36.1 Maternal care for other isoimmunisation	0.582	0.418
O90 Complications of the puerperium, not elsewhere classified	0.583	0.417
O34.7 Maternal care for abnormality of vulva and perineum	0.583	0.417
O05 Other abortion	0.584	0.416
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.585	0.415
O74 Complications of anaesthesia during labour and delivery	0.585	0.415
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.586	0.414
O07 Failed attempted abortion	0.586	0.413
O23 Infections of genito-urinary tract in pregnancy	0.588	0.412
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.589	0.411
O28 Abnormal findings on antenatal screening of mother	0.589	0.411
O71 Other obstetric trauma	0.591	0.409
O33 Maternal care for known or suspected disproportion	0.591	0.409
O83 Other assisted single delivery	0.591	0.409
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.591	0.408
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.592	0.408
O89 Complications of anaesthesia during the puerperium	0.593	0.407
O24 Diabetes mellitus in pregnancy	0.593	0.407
O03.4 Incomplete, without complication	0.595	0.405
O31 Complications specific to multiple gestation	0.595	0.405
O97 Death from sequelae of direct obstetric causes	0.595	0.405
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.595	0.405
O95 Obstetric death of unspecified cause	0.595	0.405
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.595	0.405
O41 Other disorders of amniotic fluid and membranes	0.595	0.405
O04 Medical abortion	0.595	0.404
O29 Complications of anaesthesia during pregnancy	0.596	0.404
O25 Malnutrition in pregnancy	0.596	0.404
O65 Obstructed labour due to maternal pelvic abnormality	0.596	0.403
O42 Premature rupture of membranes	0.597	0.402
O87 Venous complications in the puerperium	0.599	0.401
O08 Complications following abortion and ectopic and molar pregnancy	0.599	0.401
O81 Single delivery by forceps and vacuum extractor	0.599	0.401
O66 Other obstructed labour	0.600	0.399
O36.8 Maternal care for other specified foetal problems	0.601	0.399
O62.3 Precipitate labour	0.602	0.398
O02.0 Blighted ovum and nonhydatidiform mole	0.602	0.398
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.604	0.396
O36.2 Maternal care for hydrops foetalis	0.606	0.394
O62.0 Primary inadequate contractions	0.607	0.393
O63.1 Prolonged second stage (of labour)	0.607	0.393
O91 Infections of breast associated with childbirth	0.607	0.393
O72 Postpartum haemorrhage	0.608	0.392
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.609	0.391
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.610	0.390
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.610	0.389
O30 Multiple gestation	0.611	0.389
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.611	0.389
O43.1 Malformation of placenta	0.611	0.389
O64 Obstructed labour due to malposition and malpresentation of foetus	0.611	0.389
O21 Excessive vomiting in pregnancy	0.615	0.385
O26.5 Maternal hypotension syndrome	0.617	0.383
O02.8 Other specified abnormal products of conception	0.618	0.382
O88 Obstetric embolism	0.619	0.381
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.619	0.380
O26.0 Excessive weight gain in pregnancy	0.620	0.379
O62.2 Other uterine inertia	0.621	0.379
O02.9 Abnormal product of conception, unspecified	0.621	0.379
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.623	0.377
O85 Puerperal sepsis	0.623	0.377
O35 Maternal care for known or suspected foetal abnormality and damage	0.624	0.376
O20.8 Other haemorrhage in early pregnancy	0.624	0.376
O00.1 Tubal pregnancy	0.625	0.375
O80.8 Other single spontaneous delivery	0.625	0.375
O70.3 Fourth degree perineal laceration during delivery	0.626	0.374
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.626	0.374
O22 Venous complications in pregnancy	0.626	0.374
O48 Prolonged pregnancy	0.626	0.373
O82.9 Delivery by Caesarean section, unspecified	0.627	0.372
O34.8 Maternal care for other abnormalities of pelvic organs	0.628	0.372
O82.8 Other single delivery by Caesarean section	0.629	0.371
O82.2 Delivery by Caesarean hysterectomy	0.629	0.371
O34.4 Maternal care for other abnormalities of cervix	0.630	0.370
O34.0 Maternal care for congenital malformation of uterus	0.630	0.370
O36.3 Maternal care for signs of foetal hypoxia	0.633	0.367
O63.9 Long labour, unspecified	0.633	0.367
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.634	0.366
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.634	0.365
O62.1 Secondary uterine inertia	0.635	0.365
O26.2 Pregnancy care of habitual aborter	0.636	0.364
O34.3 Maternal care for cervical incompetence	0.638	0.362
O63.2 Delayed delivery of second twin, triplet, etc.	0.638	0.362
O36.4 Maternal care for intra-uterine death	0.638	0.362
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.638	0.361
O34.6 Maternal care for abnormality of vagina	0.639	0.360
O34.5 Maternal care for other abnormalities of gravid uterus	0.640	0.360
O26.4 Herpes gestationis	0.640	0.359
O26.1 Low weight gain in pregnancy	0.640	0.359
O47 False labour	0.641	0.359
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.642	0.358
O92 Other disorders of breast and lactation associated with childbirth	0.643	0.357
O34.1 Maternal care for tumour of corpus uteri	0.645	0.355
O69 Labour and delivery complicated by umbilical cord complications	0.646	0.354
O70.9 Perineal laceration during delivery, unspecified	0.646	0.354
O62.8 Other abnormalities of forces of labour	0.646	0.354
O03.9 Complete or unspecified, without complication	0.647	0.353
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.647	0.353
O80.1 Spontaneous breech delivery	0.648	0.352
O62.9 Abnormality of forces of labour, unspecified	0.651	0.349
O03.8 Complete or unspecified, with other and unspecified complications	0.652	0.348
O90.8 Other complications of the puerperium, not elsewhere classified	0.654	0.346
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.654	0.346
O86.1 Other infection of genital tract following delivery	0.655	0.345
O61.0 Failed medical induction of labour	0.656	0.344
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.657	0.343
O03.7 Complete or unspecified, complicated by embolism	0.659	0.341
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.659	0.341
O03.2 Incomplete, complicated by embolism	0.659	0.341
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.659	0.341
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.659	0.341
O44.1 Placenta praevia with haemorrhage	0.664	0.336
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.664	0.336
O70.0 First degree perineal laceration during delivery	0.665	0.335
O44.0 Placenta praevia specified as without haemorrhage	0.665	0.334
O03.3 Incomplete, with other and unspecified complications	0.666	0.334
O75.0 Maternal distress during labour and delivery	0.669	0.331
O43.0 Placental transfusion syndromes	0.669	0.330
O32.1 Maternal care for breech presentation	0.671	0.329
O73.0 Retained placenta, without haemorrhage	0.672	0.328
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.673	0.326
O61.1 Failed instrumental induction of labour	0.675	0.325
O00.8 Other ectopic pregnancy	0.675	0.325
O00.2 Ovarian pregnancy	0.675	0.325
O00.0 Abdominal pregnancy	0.675	0.325
O43.2 Morbidly adherent placenta	0.675	0.324
O75.8 Other specified complications of labour and delivery	0.677	0.323
O86.0 Infection of obstetric surgical wound	0.678	0.322
O61.8 Other failed induction of labour	0.679	0.320
O46.8 Other antepartum haemorrhage	0.680	0.320
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.680	0.319
O32.8 Maternal care for other malpresentation of foetus	0.681	0.319
O32.9 Maternal care for malpresentation of foetus, unspecified	0.681	0.319
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.682	0.318
O42.9 Premature rupture of membranes, unspecified	0.683	0.317
O43.9 Placental disorder, unspecified	0.683	0.316
O75.4 Other complications of obstetric surgery and procedures	0.685	0.315
O75.1 Shock during or following labour and delivery	0.685	0.315
O86.4 Pyrexia of unknown origin following delivery	0.685	0.314
O61.9 Failed induction of labour, unspecified	0.687	0.313
O23.5 Infections of the genital tract in pregnancy	0.687	0.313
O32.2 Maternal care for transverse and oblique lie	0.687	0.312
O45.9 Premature separation of placenta, unspecified	0.688	0.312
O01.9 Hydatidiform mole, unspecified	0.688	0.312
O90.1 Disruption of perineal obstetric wound	0.688	0.312
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.688	0.312
O72.1 Other immediate postpartum haemorrhage	0.689	0.311
O75.9 Complication of labour and delivery, unspecified	0.689	0.311
O75.5 Delayed delivery after artificial rupture of membranes	0.690	0.310
O84.2 Multiple delivery, all by Caesarean section	0.690	0.310
O75.3 Other infection during labour	0.690	0.310
O06.9 Complete or unspecified, without complication	0.690	0.309
O75.2 Pyrexia during labour, not elsewhere classified	0.691	0.309
O04.9 Complete or unspecified, without complication	0.691	0.309
O86.2 Urinary tract infection following delivery	0.692	0.308
O86.3 Other genito-urinary tract infections following delivery	0.692	0.308
O41.8 Other specified disorders of amniotic fluid and membranes	0.693	0.307
O21.9 Vomiting of pregnancy, unspecified	0.693	0.306
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.694	0.305
O26.9 Pregnancy-related condition, unspecified	0.695	0.305
O45.8 Other premature separation of placenta	0.695	0.305
O45.0 Premature separation of placenta with coagulation defect	0.695	0.305
O60.3 Preterm delivery without spontaneous labour	0.695	0.305
O60.2 Preterm spontaneous labour with term delivery	0.695	0.305
O60.1 Preterm spontaneous labour with preterm delivery	0.695	0.305
O60.0 Preterm labour without delivery	0.695	0.305
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.696	0.304
O32.6 Maternal care for compound presentation	0.696	0.304
O80.9 Single spontaneous delivery, unspecified	0.696	0.304
O32.0 Maternal care for unstable lie	0.696	0.303
O86.8 Other specified puerperal infections	0.697	0.303
O46.0 Antepartum haemorrhage with coagulation defect	0.697	0.303
O28.0 Abnormal haematological finding on antenatal screening of mother	0.697	0.303
O01.1 Incomplete and partial hydatidiform mole	0.697	0.303
O32.3 Maternal care for face, brow and chin presentation	0.698	0.302
O06.8 Complete or unspecified, with other and unspecified complications	0.698	0.302
O06.7 Complete or unspecified, complicated by embolism	0.698	0.302
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.698	0.302
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.698	0.302
O06.3 Incomplete, with other and unspecified complications	0.698	0.302
O06.2 Incomplete, complicated by embolism	0.698	0.302
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.698	0.302
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.698	0.302
O87.2 Haemorrhoids in the puerperium	0.698	0.302
O84.9 Multiple delivery, unspecified	0.698	0.301
O84.8 Other multiple delivery	0.698	0.301
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.698	0.301
O84.0 Multiple delivery, all spontaneous	0.698	0.301
O81.3 Other and unspecified forceps delivery	0.698	0.301
O00.9 Ectopic pregnancy, unspecified	0.698	0.301
O01.0 Classical hydatidiform mole	0.700	0.299
O90.5 Postpartum thyroiditis	0.701	0.299
O90.4 Postpartum acute renal failure	0.701	0.299
O90.3 Cardiomyopathy in the puerperium	0.701	0.299
O71.9 Obstetric trauma, unspecified	0.701	0.299
O06.4 Incomplete, without complication	0.701	0.299
O05.9 Complete or unspecified, without complication	0.701	0.298
O05.8 Complete or unspecified, with other and unspecified complications	0.701	0.298
O05.7 Complete or unspecified, complicated by embolism	0.701	0.298
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.701	0.298
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.701	0.298
O05.4 Incomplete, without complication	0.701	0.298
O05.3 Incomplete, with other and unspecified complications	0.701	0.298
O05.2 Incomplete, complicated by embolism	0.701	0.298
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.701	0.298
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.701	0.298
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.702	0.298
O91.1 Abscess of breast associated with childbirth	0.702	0.297
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.702	0.297
O74.8 Other complications of anaesthesia during labour and delivery	0.702	0.297
O74.7 Failed or difficult intubation during labour and delivery	0.702	0.297
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.702	0.297
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.702	0.297
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.702	0.297
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.702	0.297
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.702	0.297
O67.0 Intrapartum haemorrhage with coagulation defect	0.703	0.297
O07.9 Other and unspecified failed attempted abortion, without complication	0.703	0.296
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.703	0.296
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.703	0.296
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.703	0.296
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.703	0.296
O07.3 Failed medical abortion, with other and unspecified complications	0.703	0.296
O07.2 Failed medical abortion, complicated by embolism	0.703	0.296
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.703	0.296
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.703	0.296
O71.8 Other specified obstetric trauma	0.703	0.296
O87.9 Venous complication in the puerperium, unspecified	0.703	0.296
O71.4 Obstetric high vaginal laceration alone	0.704	0.296
O23.3 Infections of other parts of urinary tract in pregnancy	0.704	0.296
O23.2 Infections of urethra in pregnancy	0.704	0.296
O23.1 Infections of bladder in pregnancy	0.704	0.296
O66.8 Other specified obstructed labour	0.705	0.295
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.705	0.295
O28.8 Other abnormal findings on antenatal screening of mother	0.705	0.294
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.705	0.294
O28.4 Abnormal radiological finding on antenatal screening of mother	0.705	0.294
O28.2 Abnormal cytological finding on antenatal screening of mother	0.705	0.294
O07.4 Failed medical abortion, without complication	0.706	0.294
O71.2 Postpartum inversion of uterus	0.706	0.293
O71.1 Rupture of uterus during labour	0.706	0.293
O71.0 Rupture of uterus before onset of labour	0.706	0.293
O33.8 Maternal care for disproportion of other origin	0.707	0.293
O33.7 Maternal care for disproportion due to other foetal deformities	0.707	0.293
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.707	0.293
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.707	0.293
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.707	0.293
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.707	0.293
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.707	0.293
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.707	0.293
O83.9 Assisted single delivery, unspecified	0.707	0.293
O83.8 Other specified assisted single delivery	0.707	0.293
O83.4 Destructive operation for delivery	0.707	0.293
O83.3 Delivery of viable foetus in abdominal pregnancy	0.707	0.293
O83.2 Other manipulation-assisted delivery	0.707	0.293
O83.0 Breech extraction	0.707	0.293
O24.4 Diabetes mellitus arising in pregnancy	0.707	0.293
O87.8 Other venous complications in the puerperium	0.707	0.293
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.707	0.292
O67.8 Other intrapartum haemorrhage	0.708	0.292
O24.9 Diabetes mellitus in pregnancy, unspecified	0.708	0.292
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.708	0.292
O89.8 Other complications of anaesthesia during the puerperium	0.708	0.292
O89.6 Failed or difficult intubation during the puerperium	0.708	0.292
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.708	0.292
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.708	0.292
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.708	0.292
O89.1 Cardiac complications of anaesthesia during the puerperium	0.708	0.292
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.708	0.292
O90.0 Disruption of Caesarean section wound	0.708	0.292
O24.3 Pre-existing diabetes mellitus, unspecified	0.708	0.292
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.708	0.292
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.708	0.292
O64.8 Obstructed labour due to other malposition and malpresentation	0.708	0.292
O23.0 Infections of kidney in pregnancy	0.708	0.291
O67.9 Intrapartum haemorrhage, unspecified	0.709	0.291
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.709	0.291
O31.0 Papyraceous foetus	0.709	0.290
O96.9 Death from unspecified obstetric cause	0.709	0.290
O96.1 Death from indirect obstetric cause	0.709	0.290
O96.0 Death from direct obstetric cause	0.709	0.290
O97.9 Death from sequelae of obstetric cause, unspecified	0.709	0.290
O97.1 Death from sequelae of indirect obstetric cause	0.709	0.290
O97.0 Death from sequelae of direct obstetric cause	0.709	0.290
O04.7 Complete or unspecified, complicated by embolism	0.710	0.290
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.710	0.290
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.710	0.290
O04.3 Incomplete, with other and unspecified complications	0.710	0.290
O04.2 Incomplete, complicated by embolism	0.710	0.290
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.710	0.290
O33.9 Maternal care for disproportion, unspecified	0.710	0.290
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.710	0.290
O29.8 Other complications of anaesthesia during pregnancy	0.710	0.290
O29.6 Failed or difficult intubation during pregnancy	0.710	0.290
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.710	0.290
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.710	0.290
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.710	0.290
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.710	0.290
O29.1 Cardiac complications of anaesthesia during pregnancy	0.710	0.290
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.710	0.290
O83.1 Other assisted breech delivery	0.710	0.290
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.710	0.290
O71.6 Obstetric damage to pelvic joints and ligaments	0.710	0.290
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.710	0.289
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.710	0.289
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.710	0.289
O65.2 Obstructed labour due to pelvic inlet contraction	0.710	0.289
O65.1 Obstructed labour due to generally contracted pelvis	0.710	0.289
O65.0 Obstructed labour due to deformed pelvis	0.710	0.289
O71.3 Obstetric laceration of cervix	0.711	0.289
O75.7 Vaginal delivery following previous Caesarean section	0.711	0.288
O46.9 Antepartum haemorrhage, unspecified	0.712	0.288
O90.2 Haematoma of obstetric wound	0.712	0.288
O31.1 Continuing pregnancy after abortion of one foetus or more	0.712	0.288
O87.3 Cerebral venous thrombosis in the puerperium	0.712	0.288
O87.1 Deep phlebothrombosis in the puerperium	0.712	0.288
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.712	0.288
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.712	0.288
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.712	0.288
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.712	0.288
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.712	0.288
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.712	0.288
O08.3 Shock following abortion and ectopic and molar pregnancy	0.712	0.288
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.712	0.288
O33.5 Maternal care for disproportion due to unusually large foetus	0.712	0.287
O64.5 Obstructed labour due to compound presentation	0.712	0.287
O81.5 Delivery by combination of forceps and vacuum extractor	0.712	0.287
O81.2 Mid-cavity forceps with rotation	0.712	0.287
O81.1 Mid-cavity forceps delivery	0.712	0.287
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.713	0.287
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.713	0.287
O71.5 Other obstetric injury to pelvic organs	0.713	0.287
O66.3 Obstructed labour due to other abnormalities of foetus	0.713	0.286
O66.1 Obstructed labour due to locked twins	0.713	0.286
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.714	0.286
O31.8 Other complications specific to multiple gestation	0.714	0.285
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.714	0.285
O04.8 Complete or unspecified, with other and unspecified complications	0.715	0.285
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.715	0.285
O90.9 Complication of the puerperium, unspecified	0.715	0.285
O32.4 Maternal care for high head at term	0.716	0.284
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.716	0.284
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.716	0.284
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.716	0.284
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.716	0.284
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.716	0.284
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.716	0.284
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.716	0.284
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.716	0.284
O41.1 Infection of amniotic sac and membranes	0.716	0.283
O42.2 Premature rupture of membranes, labour delayed by therapy	0.717	0.283
O66.9 Obstructed labour, unspecified	0.717	0.283
O91.0 Infection of nipple associated with childbirth	0.718	0.282
O72.3 Postpartum coagulation defects	0.719	0.281
O04.4 Incomplete, without complication	0.719	0.281
O71.7 Obstetric haematoma of pelvis	0.719	0.281
O64.1 Obstructed labour due to breech presentation	0.719	0.281
O66.2 Obstructed labour due to unusually large foetus	0.719	0.281
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.719	0.281
O87.0 Superficial thrombophlebitis in the puerperium	0.719	0.280
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.720	0.280
O20.0 Threatened abortion	0.720	0.279
O30.9 Multiple gestation, unspecified	0.721	0.279
O30.8 Other multiple gestation	0.721	0.279
O30.2 Quadruplet pregnancy	0.721	0.279
O64.4 Obstructed labour due to shoulder presentation	0.721	0.279
O23.4 Unspecified infection of urinary tract in pregnancy	0.722	0.278
O91.2 Nonpurulent mastitis associated with childbirth	0.722	0.277
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.722	0.277
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.723	0.277
O66.4 Failed trial of labour, unspecified	0.723	0.276
O64.3 Obstructed labour due to brow presentation	0.724	0.276
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.724	0.275
O81.0 Low forceps delivery	0.725	0.275
O64.2 Obstructed labour due to face presentation	0.725	0.274
O66.0 Obstructed labour due to shoulder dystocia	0.726	0.274
O30.1 Triplet pregnancy	0.726	0.273
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.726	0.273
O88.8 Other obstetric embolism	0.726	0.273
O88.3 Obstetric pyaemic and septic embolism	0.726	0.273
O88.2 Obstetric blood-clot embolism	0.726	0.273
O88.1 Amniotic fluid embolism	0.726	0.273
O88.0 Obstetric air embolism	0.726	0.273
O81.4 Vacuum extractor delivery	0.727	0.273
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.729	0.271
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.730	0.270
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.730	0.270
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.730	0.270
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.730	0.270
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.730	0.270
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.730	0.270
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.731	0.269
O21.8 Other vomiting complicating pregnancy	0.731	0.268
O22.9 Venous complication in pregnancy, unspecified	0.732	0.268
O22.8 Other venous complications in pregnancy	0.732	0.268
O22.5 Cerebral venous thrombosis in pregnancy	0.732	0.268
O22.2 Superficial thrombophlebitis in pregnancy	0.732	0.268
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.732	0.267
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.734	0.266
O43.8 Other placental disorders	0.734	0.266
O21.2 Late vomiting of pregnancy	0.734	0.266
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.735	0.265
O22.1 Genital varices in pregnancy	0.735	0.265
O22.3 Deep phlebothrombosis in pregnancy	0.736	0.263
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.737	0.262
O69.8 Labour and delivery complicated by other cord complications	0.738	0.261
O22.0 Varicose veins of lower extremity in pregnancy	0.739	0.260
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.740	0.260
O30.0 Twin pregnancy	0.743	0.257
O22.4 Haemorrhoids in pregnancy	0.743	0.256
O92.7 Other and unspecified disorders of lactation	0.744	0.256
O92.6 Galactorrhoea	0.744	0.256
O92.5 Suppressed lactation	0.744	0.256
O92.4 Hypogalactia	0.744	0.256
O92.3 Agalactia	0.744	0.256
O92.0 Retracted nipple associated with childbirth	0.744	0.256
O72.2 Delayed and secondary postpartum haemorrhage	0.746	0.254
O69.5 Labour and delivery complicated by vascular lesion of cord	0.746	0.254
O69.4 Labour and delivery complicated by vasa praevia	0.746	0.254
O69.3 Labour and delivery complicated by short cord	0.746	0.254
O41.0 Oligohydramnios	0.747	0.253
O47.9 False labour, unspecified	0.747	0.252
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.748	0.252
O69.9 Labour and delivery complicated by cord complication, unspecified	0.750	0.249
O92.1 Cracked nipple associated with childbirth	0.753	0.246
O21.0 Mild hyperemesis gravidarum	0.753	0.246
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.754	0.246
O15 Eclampsia	0.755	0.245
O69.0 Labour and delivery complicated by prolapse of cord	0.757	0.243
O92.2 Other and unspecified disorders of breast associated with childbirth	0.757	0.243
O47.1 False labour at or after 37 completed weeks of gestation	0.760	0.240
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.760	0.240
O16 Unspecified maternal hypertension	0.760	0.239
O72.0 Third-stage haemorrhage	0.766	0.234
O69.2 Labour and delivery complicated by other cord entanglement	0.768	0.232
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.769	0.231
O47.0 False labour before 37 completed weeks of gestation	0.772	0.228
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.775	0.224
O69.1 Labour and delivery complicated by cord around neck, with compression	0.778	0.222
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.778	0.222
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.780	0.220
O15.9 Eclampsia, unspecified as to time period	0.824	0.175
O15.1 Eclampsia in labour	0.824	0.175
O15.0 Eclampsia in pregnancy	0.824	0.175
O15.2 Eclampsia in the puerperium	0.826	0.174
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.834	0.166
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.834	0.166
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.834	0.166

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations