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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516509
log Bayes Factor = 97.2534
Chromosome 6   position 31,449,994  (GRCh37) Explore rs2516509 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
M07.3 Other psoriatic arthropathies
0.997 0.003 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.997 0.003 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.995 0.005 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.993 0.007 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.991 0.009 0.000
T39.1 4-Aminophenol derivatives
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.021 0.979
E10-E14 Diabetes mellitus
0.000 0.021 0.979
T46 Poisoning by agents primarily affecting the cardiovascular system
0.970 0.030 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.969 0.031 0.000
E10.3 With ophthalmic complications
0.000 0.038 0.962
T43.5 Other and unspecified antipsychotics and neuroleptics
0.953 0.047 0.000
L40.0 Psoriasis vulgaris
0.948 0.052 0.000
E06 Thyroiditis
0.000 0.055 0.945
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.944 0.056 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.925 0.075 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.925 0.075 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.918 0.082 0.000
E10.1 With ketoacidosis
0.000 0.090 0.910
T45.0 Antiallergic and antiemetic drugs
0.910 0.090 0.000
E06.3 Autoimmune thyroiditis
0.000 0.103 0.897
T43.3 Phenothiazine antipsychotics and neuroleptics
0.896 0.104 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.108 0.892
E27 Other disorders of adrenal gland
0.000 0.115 0.885
T43.2 Other and unspecified antidepressants
0.883 0.117 0.000
T39.0 Salicylates
0.883 0.117 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.883 0.117 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.121 0.879
M07.36 Other psoriatic arthropathies (Lower leg)
0.872 0.128 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.866 0.134 0.000
E10.0 With coma
0.000 0.137 0.863
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.855 0.145 0.000
T46.1 Calcium-channel blockers
0.854 0.146 0.000
E10.4 With neurological complications
0.000 0.148 0.852
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.838 0.162 0.000
L40.1 Generalised pustular psoriasis
0.836 0.164 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.835 0.165 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.834 0.166 0.000
E03.8 Other specified hypothyroidism
0.000 0.168 0.832
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.168 0.832
T43.6 Psychostimulants with abuse potential
0.825 0.175 0.000
M45-M49 Spondylopathies
0.813 0.187 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.805 0.195 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.803 0.197 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.800 0.200 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.800 0.200 0.000
E10.2 With renal complications
0.000 0.201 0.798
G37 Other demyelinating diseases of central nervous system
0.000 0.202 0.798
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.795 0.205 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.795 0.205 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.791 0.209 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.790 0.210 0.000
L40.4 Guttate psoriasis
0.783 0.217 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.780 0.220 0.000
T38.1 Thyroid hormones and substitutes
0.774 0.226 0.000
T42.4 Benzodiazepines
0.771 0.229 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.768 0.231 0.000
L40.8 Other psoriasis
0.766 0.234 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.763 0.237 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.237 0.763
M07 Psoriatic and enteropathic arthropathies
0.759 0.240 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.756 0.244 0.000
E07 Other disorders of thyroid
0.000 0.245 0.754
E27.9 Disorder of adrenal gland, unspecified
0.000 0.254 0.746
K90 Intestinal malabsorption
0.000 0.257 0.743
M47 Spondylosis
0.732 0.268 0.000
L40.3 Pustulosis palmaris et plantaris
0.731 0.269 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.723 0.277 0.000
E40-E46 Malnutrition
0.000 0.277 0.722
E06.9 Thyroiditis, unspecified
0.000 0.278 0.722
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.722 0.278 0.000
T42.1 Iminostilbenes
0.722 0.278 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E10.7 With multiple complications
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.715 0.285 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.715 0.285 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.715 0.285 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.715 0.285 0.000
T39.4 Antirheumatics, not elsewhere classified
0.713 0.287 0.000
T39.2 Pyrazolone derivatives
0.713 0.287 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.713 0.287 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.712 0.288 0.000
T43.9 Psychotropic drug, unspecified
0.710 0.289 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.710 0.289 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.707 0.293 0.000
E20 Hypoparathyroidism
0.000 0.298 0.702
E27.2 Addisonian crisis
0.000 0.298 0.702
E12 Malnutrition-related diabetes mellitus
0.000 0.298 0.702
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.701 0.299 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.695 0.304 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.695 0.304 0.000
T46.7 Peripheral vasodilators
0.695 0.304 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.695 0.304 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.695 0.305 0.000
T42.3 Barbiturates
0.695 0.305 0.000
T42.2 Succinimides and oxazolidinediones
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.688 0.312 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.312 0.688
K90.9 Intestinal malabsorption, unspecified
0.000 0.321 0.679
T42.0 Hydantoin derivatives
0.679 0.321 0.000
E06.5 Other chronic thyroiditis
0.000 0.323 0.677
E06.4 Drug-induced thyroiditis
0.000 0.323 0.677
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.323 0.677
E06.1 Subacute thyroiditis
0.000 0.323 0.677
E06.0 Acute thyroiditis
0.000 0.323 0.677
T45.9 Primarily systemic and haematological agent, unspecified
0.677 0.323 0.000
T45.8 Other primarily systemic and haematological agents
0.677 0.323 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.677 0.323 0.000
T45.6 Fibrinolysis-affecting drugs
0.677 0.323 0.000
T45.4 Iron and its compounds
0.677 0.323 0.000
T45.3 Enzymes, not elsewhere classified
0.677 0.323 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.325 0.675
T36 Poisoning by systemic antibiotics
0.675 0.325 0.000
M47.8 Other spondylosis
0.672 0.328 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.663 0.337 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.663 0.337 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.663 0.337 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.663 0.337 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.663 0.337 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.663 0.337 0.000
T44.0 Anticholinesterase agents
0.663 0.337 0.000
T38.9 Other and unspecified hormone antagonists
0.663 0.337 0.000
T38.7 Androgens and anabolic congeners
0.663 0.337 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.663 0.337 0.000
T38.5 Other oestrogens and progestogens
0.663 0.337 0.000
T38.4 Oral contraceptives
0.663 0.337 0.000
T38.2 Antithyroid drugs
0.663 0.337 0.000
T38.0 Glucocorticoids and synthetic analogues
0.663 0.337 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.659 0.341 0.000
E05.8 Other thyrotoxicosis
0.000 0.344 0.656
M47.80 Other spondylosis (Multiple sites in spine)
0.656 0.344 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.348 0.652
T47.1 Other antacids and anti-gastric-secretion drugs
0.649 0.351 0.000
T45.2 Vitamins, not elsewhere classified
0.644 0.356 0.000
E25 Adrenogenital disorders
0.000 0.357 0.643
T46.3 Coronary vasodilators, not elsewhere classified
0.641 0.359 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.360 0.640
E32 Diseases of thymus
0.000 0.360 0.640
E31 Polyglandular dysfunction
0.000 0.360 0.640
E30 Disorders of puberty, not elsewhere classified
0.000 0.360 0.640
E07.9 Disorder of thyroid, unspecified
0.000 0.363 0.637
E27.5 Adrenomedullary hyperfunction
0.000 0.365 0.635
E27.0 Other adrenocortical overactivity
0.000 0.365 0.635
E10.6 With other specified complications
0.000 0.375 0.624
T50.7 Analeptics and opioid receptor antagonists
0.621 0.379 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.621 0.379 0.000
T50.5 Appetite depressants
0.621 0.379 0.000
T50.4 Drugs affecting uric acid metabolism
0.621 0.379 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.621 0.379 0.000
T50.1 Loop [high-ceiling] diuretics
0.621 0.379 0.000
T50.0 Mineralocorticoids and their antagonists
0.621 0.379 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.384 0.616
T50.8 Diagnostic agents
0.609 0.391 0.000
E26 Hyperaldosteronism
0.000 0.391 0.609
G36 Other acute disseminated demyelination
0.000 0.403 0.596
E65-E68 Obesity and other hyperalimentation
0.000 0.406 0.594
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.406 0.594
M05-M14 Inflammatory polyarthropathies
0.589 0.411 0.000
E34 Other endocrine disorders
0.000 0.412 0.588
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.586 0.414 0.000
E10.8 With unspecified complications
0.000 0.423 0.577
E03.1 Congenital hypothyroidism without goitre
0.000 0.425 0.575
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.572 0.428 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.428 0.572
G37.4 Subacute necrotising myelitis
0.000 0.428 0.572
G37.2 Central pontine myelinolysis
0.000 0.428 0.572
G37.1 Central demyelination of corpus callosum
0.000 0.428 0.572
G37.0 Diffuse sclerosis
0.000 0.428 0.572
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.428 0.572
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.570 0.430 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.570 0.430 0.000
T47.7 Emetics
0.570 0.430 0.000
T47.6 Antidiarrhoeal drugs
0.570 0.430 0.000
T47.5 Digestants
0.570 0.430 0.000
T47.4 Other laxatives
0.570 0.430 0.000
T47.3 Saline and osmotic laxatives
0.570 0.430 0.000
T47.2 Stimulant laxatives
0.570 0.430 0.000
T47.0 Histamine H(2)-receptor antagonists
0.570 0.430 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.430 0.570
E20.9 Hypoparathyroidism, unspecified
0.000 0.434 0.566
M48 Other spondylopathies
0.565 0.435 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.441 0.559
E10.5 With peripheral circulatory complications
0.000 0.442 0.558
K90.8 Other intestinal malabsorption
0.000 0.444 0.555
M91-M94 Chondropathies
0.554 0.446 0.000
E28 Ovarian dysfunction
0.000 0.446 0.554
M47.83 Other spondylosis (Cervicothoracic region)
0.551 0.449 0.000
M47.82 Other spondylosis (Cervical region)
0.547 0.453 0.000
M47.1 Other spondylosis with myelopathy
0.546 0.454 0.000
M07.6 Other enteropathic arthropathies
0.545 0.455 0.000
M07.5 Arthropathy in ulcerative colitis
0.545 0.455 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.545 0.455 0.000
M07.2 Psoriatic spondylitis
0.545 0.455 0.000
M07.1 Arthritis mutilans
0.545 0.455 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.545 0.455 0.000
M47.84 Other spondylosis (Thoracic region)
0.542 0.458 0.000
E07.1 Dyshormogenetic goitre
0.000 0.459 0.541
E07.0 Hypersecretion of calcitonin
0.000 0.459 0.541
M46 Other inflammatory spondylopathies
0.540 0.460 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.461 0.539
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.462 0.538
M47.9 Spondylosis, unspecified
0.533 0.467 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.467 0.533
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.467 0.533
K90.1 Tropical sprue
0.000 0.467 0.533
E29 Testicular dysfunction
0.000 0.468 0.531
M49 Spondylopathies in diseases classified elsewhere
0.531 0.469 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.470 0.530
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.470 0.530
M47.0 Anterior spinal and vertebral artery compression syndromes
0.525 0.475 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.524 0.476 0.000
T36.4 Tetracyclines
0.519 0.481 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.482 0.518
E45 Retarded development following protein-energy malnutrition
0.000 0.482 0.518
E43 Unspecified severe protein-energy malnutrition
0.000 0.482 0.518
E42 Marasmic kwashiorkor
0.000 0.482 0.518
E41 Nutritional marasmus
0.000 0.482 0.518
E40 Kwashiorkor
0.000 0.482 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
T41.5 Therapeutic gases
0.514 0.486 0.000
T41.4 Anaesthetic, unspecified
0.514 0.486 0.000
T41.3 Local anaesthetics
0.514 0.486 0.000
T41.2 Other and unspecified general anaesthetics
0.514 0.486 0.000
T41.1 Intravenous anaesthetics
0.514 0.486 0.000
T41.0 Inhaled anaesthetics
0.514 0.486 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.514 0.486 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.514 0.486 0.000
T48.5 Anti-common-cold drugs
0.514 0.486 0.000
T48.4 Expectorants
0.514 0.486 0.000
T48.3 Antitussives
0.514 0.486 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.514 0.486 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.514 0.486 0.000
T48.0 Oxytocic drugs
0.514 0.486 0.000
T49.9 Topical agent, unspecified
0.514 0.486 0.000
T49.8 Other topical agents
0.514 0.486 0.000
T49.7 Dental drugs, topically applied
0.514 0.486 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.514 0.486 0.000
T49.5 Ophthalmological drugs and preparations
0.514 0.486 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.514 0.486 0.000
T49.3 Emollients, demulcents and protectants
0.514 0.486 0.000
T49.2 Local astringents and local detergents
0.514 0.486 0.000
T49.1 Antipruritics
0.514 0.486 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.514 0.486 0.000
M94 Other disorders of cartilage
0.513 0.487 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.487 0.513
E13 Other specified diabetes mellitus
0.000 0.490 0.510
E65 Localised adiposity
0.000 0.492 0.508
M47.2 Other spondylosis with radiculopathy
0.505 0.495 0.000
E20.8 Other hypoparathyroidism
0.000 0.496 0.503
E20.1 Pseudohypoparathyroidism
0.000 0.496 0.503
E20.0 Idiopathic hypoparathyroidism
0.000 0.496 0.503
E12.9 Without complications
0.000 0.497 0.503
E12.8 With unspecified complications
0.000 0.497 0.503
E12.7 With multiple complications
0.000 0.497 0.503
E12.6 With other specified complications
0.000 0.497 0.503
E12.5 With peripheral circulatory complications
0.000 0.497 0.503
E12.4 With neurological complications
0.000 0.497 0.503
E12.3 With ophthalmic complications
0.000 0.497 0.503
E12.2 With renal complications
0.000 0.497 0.503
E12.1 With ketoacidosis
0.000 0.497 0.503
E12.0 With coma
0.000 0.497 0.503
M47.89 Other spondylosis (Site unspecified)
0.502 0.498 0.000
M92 Other juvenile osteochondrosis
0.500 0.500 0.000
M86-M90 Other osteopathies
0.497 0.502 0.000
T45.5 Anticoagulants
0.496 0.504 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.493 0.506 0.000
T37.5 Antiviral drugs
0.493 0.506 0.000
T37.4 Anthelminthics
0.493 0.506 0.000
T37.3 Other antiprotozoal drugs
0.493 0.506 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.493 0.506 0.000
T37.1 Antimycobacterial drugs
0.493 0.506 0.000
T37.0 Sulphonamides
0.493 0.506 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.493 0.507 0.000
M00-M03 Infectious arthropathies
0.486 0.514 0.000
T36.9 Systemic antibiotic, unspecified
0.484 0.516 0.000
T36.8 Other systemic antibiotics
0.484 0.516 0.000
T36.7 Antifungal antibiotics, systemically used
0.484 0.516 0.000
T36.6 Rifamycins
0.484 0.516 0.000
T36.5 Aminoglycosides
0.484 0.516 0.000
T36.3 Macrolides
0.484 0.516 0.000
T36.2 Chloramphenicol group
0.484 0.516 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.484 0.516 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.482 0.518 0.000
M14 Arthropathies in other diseases classified elsewhere
0.473 0.527 0.000
E22 Hyperfunction of pituitary gland
0.000 0.530 0.470
E23.7 Disorder of pituitary gland, unspecified
0.000 0.533 0.467
M48.5 Collapsed vertebra, not elsewhere classified
0.467 0.533 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.465 0.535 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.535 0.464
E25.9 Adrenogenital disorder, unspecified
0.000 0.539 0.461
E25.8 Other adrenogenital disorders
0.000 0.539 0.461
M92.6 Juvenile osteochondrosis of tarsus
0.460 0.540 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.541 0.459
E30.8 Other disorders of puberty
0.000 0.541 0.459
E30.1 Precocious puberty
0.000 0.541 0.459
E30.0 Delayed puberty
0.000 0.541 0.459
E31.9 Polyglandular dysfunction, unspecified
0.000 0.541 0.459
E31.8 Other polyglandular dysfunction
0.000 0.541 0.459
E31.1 Polyglandular hyperfunction
0.000 0.541 0.459
E31.0 Autoimmune polyglandular failure
0.000 0.541 0.459
E32.9 Disease of thymus, unspecified
0.000 0.541 0.459
E32.8 Other diseases of thymus
0.000 0.541 0.459
E32.1 Abscess of thymus
0.000 0.541 0.459
E32.0 Persistent hyperplasia of thymus
0.000 0.541 0.459
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.541 0.459
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.541 0.459
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.541 0.459
E24 Cushing's syndrome
0.000 0.542 0.457
M94.8 Other specified disorders of cartilage
0.457 0.543 0.000
M88 Paget's disease of bone [osteitis deformans]
0.454 0.546 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.448 0.551 0.000
E23.2 Diabetes insipidus
0.000 0.553 0.447
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.553 0.447
E15 Nondiabetic hypoglycaemic coma
0.000 0.558 0.441
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.441 0.559 0.000
E50-E64 Other nutritional deficiencies
0.000 0.560 0.440
E34.8 Other specified endocrine disorders
0.000 0.562 0.437
M91 Juvenile osteochondrosis of hip and pelvis
0.437 0.563 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.563 0.437
E26.8 Other hyperaldosteronism
0.000 0.563 0.437
E26.1 Secondary hyperaldosteronism
0.000 0.563 0.437
E07.8 Other specified disorders of thyroid
0.000 0.565 0.434
M48.9 Spondylopathy, unspecified
0.432 0.568 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.432 0.568 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.572 0.428
G36.8 Other specified acute disseminated demyelination
0.000 0.572 0.428
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.572 0.428
G36.0 Neuromyelitis optica [Devic]
0.000 0.572 0.428
M48.8 Other specified spondylopathies
0.427 0.572 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.573 0.427
E67 Other hyperalimentation
0.000 0.574 0.426
E68 Sequelae of hyperalimentation
0.000 0.574 0.426
E21.2 Other hyperparathyroidism
0.000 0.574 0.426
M94.9 Disorder of cartilage, unspecified
0.425 0.575 0.000
M88.9 Paget's disease of bone, unspecified
0.423 0.577 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.423 0.577 0.000
M08 Juvenile arthritis
0.423 0.577 0.000
E34.5 Androgen resistance syndrome
0.000 0.579 0.421
E34.4 Constitutional tall stature
0.000 0.579 0.421
E34.3 Short stature, not elsewhere classified
0.000 0.579 0.421
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.579 0.421
E34.1 Other hypersecretion of intestinal hormones
0.000 0.579 0.421
M47.12 Other spondylosis with myelopathy (Cervical region)
0.417 0.583 0.000
M46.4 Discitis, unspecified
0.409 0.591 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.591 0.409
E23.1 Drug-induced hypopituitarism
0.000 0.591 0.409
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.409 0.591 0.000
M02 Reactive arthropathies
0.408 0.592 0.000
M12 Other specific arthropathies
0.408 0.592 0.000
E26.0 Primary hyperaldosteronism
0.000 0.594 0.406
M48.4 Fatigue fracture of vertebra
0.405 0.595 0.000
M48.3 Traumatic spondylopathy
0.405 0.595 0.000
M48.2 Kissing spine
0.405 0.595 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.405 0.595 0.000
E28.3 Primary ovarian failure
0.000 0.595 0.404
E23.6 Other disorders of pituitary gland
0.000 0.600 0.400
M89 Other disorders of bone
0.399 0.601 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.399 0.601 0.000
L40-L45 Papulosquamous disorders
0.398 0.602 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.398 0.602 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.603 0.397
E28.8 Other ovarian dysfunction
0.000 0.603 0.397
E28.1 Androgen excess
0.000 0.603 0.397
E28.0 Oestrogen excess
0.000 0.603 0.397
M94.86 Other specified disorders of cartilage (Lower leg)
0.396 0.603 0.000
M87 Osteonecrosis
0.395 0.605 0.000
M06 Other rheumatoid arthritis
0.395 0.605 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.607 0.393
E22.0 Acromegaly and pituitary gigantism
0.000 0.608 0.392
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.391 0.609 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.391 0.609 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.391 0.609 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.391 0.609 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.391 0.609 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.391 0.609 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.391 0.609 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.391 0.609 0.000
T36.0 Penicillins
0.391 0.609 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.390 0.609 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.390 0.609 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.390 0.609 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.390 0.609 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.390 0.609 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.390 0.609 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.390 0.609 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.390 0.609 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.390 0.609 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.390 0.609 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.390 0.609 0.000
M07.18 Arthritis mutilans (Other)
0.390 0.609 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.390 0.609 0.000
M07.16 Arthritis mutilans (Lower leg)
0.390 0.609 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.390 0.609 0.000
M07.14 Arthritis mutilans (Hand)
0.390 0.609 0.000
M07.13 Arthritis mutilans (Forearm)
0.390 0.609 0.000
M07.12 Arthritis mutilans (Upper arm)
0.390 0.609 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.390 0.609 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.390 0.609 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.390 0.609 0.000
M07.28 Psoriatic spondylitis (Other)
0.390 0.609 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.390 0.609 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.390 0.609 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.390 0.609 0.000
M07.24 Psoriatic spondylitis (Hand)
0.390 0.609 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.390 0.609 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.390 0.609 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.390 0.609 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.390 0.609 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.390 0.609 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.390 0.609 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.390 0.609 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.390 0.609 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.390 0.609 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.390 0.609 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.390 0.609 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.390 0.609 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.390 0.609 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.390 0.609 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.390 0.609 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.390 0.609 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.390 0.609 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.390 0.609 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.390 0.609 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.390 0.609 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.390 0.609 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.390 0.609 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.390 0.609 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.390 0.609 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.390 0.609 0.000
M07.68 Other enteropathic arthropathies (Other)
0.390 0.609 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.390 0.609 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.390 0.609 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.390 0.609 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.390 0.609 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.390 0.609 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.390 0.609 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.390 0.609 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.390 0.609 0.000
M14.6 Neuropathic arthropathy
0.390 0.610 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.389 0.611 0.000
M46.8 Other specified inflammatory spondylopathies
0.388 0.612 0.000
M46.5 Other infective spondylopathies
0.388 0.612 0.000
M46.2 Osteomyelitis of vertebra
0.388 0.612 0.000
M46.0 Spinal enthesopathy
0.388 0.612 0.000
M94.2 Chondromalacia
0.387 0.613 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.385 0.615 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.382 0.618 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.382 0.618 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.382 0.618 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.619 0.381
E29.8 Other testicular dysfunction
0.000 0.619 0.381
E29.0 Testicular hyperfunction
0.000 0.619 0.381
M49.8 Spondylopathy in other diseases classified elsewhere
0.380 0.619 0.000
M49.4 Neuropathic spondylopathy
0.380 0.619 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.380 0.619 0.000
M49.2 Enterobacterial spondylitis
0.380 0.619 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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