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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523882
log Bayes Factor = 17.0805
Chromosome 6   position 31,042,217  (GRCh37) Explore rs2523882 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
E10.1 With ketoacidosis
0.000 0.005 0.995
E10.9 Without complications
0.000 0.008 0.992
E10.4 With neurological complications
0.000 0.074 0.926
E10.3 With ophthalmic complications
0.000 0.080 0.920
E10.5 With peripheral circulatory complications
0.000 0.084 0.916
E10.8 With unspecified complications
0.000 0.123 0.877
R31 Unspecified haematuria
0.868 0.132 0.000
E10.6 With other specified complications
0.000 0.157 0.843
E10.0 With coma
0.000 0.182 0.818
E10.2 With renal complications
0.000 0.182 0.818
M45.X9 Ankylosing spondylitis (Site unspecified)
0.735 0.265 0.000
E10.7 With multiple complications
0.000 0.284 0.716
M45 Ankylosing spondylitis
0.660 0.340 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.608 0.392 0.000
E10-E14 Diabetes mellitus
0.000 0.422 0.578
M45.X6 Ankylosing spondylitis (Lumbar region)
0.567 0.433 0.000
E14 Unspecified diabetes mellitus
0.000 0.480 0.520
M45.X2 Ankylosing spondylitis (Cervical region)
0.519 0.481 0.000
E14.3 With ophthalmic complications
0.000 0.503 0.497
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.473 0.527 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.473 0.527 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.473 0.527 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.473 0.527 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.473 0.527 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.473 0.527 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.585 0.414
E14.1 With ketoacidosis
0.000 0.596 0.404
E14.8 With unspecified complications
0.000 0.602 0.398
E14.7 With multiple complications
0.000 0.627 0.373
E14.6 With other specified complications
0.000 0.627 0.373
E14.5 With peripheral circulatory complications
0.000 0.627 0.373
E14.2 Withrenal complications
0.000 0.627 0.373
E14.0 With coma
0.000 0.627 0.373
E13 Other specified diabetes mellitus
0.000 0.632 0.368
K90 Intestinal malabsorption
0.000 0.648 0.352
E03.9 Hypothyroidism, unspecified
0.348 0.652 0.000
E14.4 With neurological complications
0.000 0.691 0.309
E12.9 Without complications
0.000 0.703 0.297
E12.8 With unspecified complications
0.000 0.703 0.297
E12.7 With multiple complications
0.000 0.703 0.297
E12.6 With other specified complications
0.000 0.703 0.297
E12.5 With peripheral circulatory complications
0.000 0.703 0.297
E12.4 With neurological complications
0.000 0.703 0.297
E12.3 With ophthalmic complications
0.000 0.703 0.297
E12.2 With renal complications
0.000 0.703 0.297
E12.1 With ketoacidosis
0.000 0.703 0.297
E12.0 With coma
0.000 0.703 0.297
E13.8 With unspecified complications
0.000 0.736 0.264
E13.7 With multiple complications
0.000 0.736 0.264
E13.6 With other specified complications
0.000 0.736 0.264
E13.5 With peripheral circulatory complications
0.000 0.736 0.264
E13.4 With neurological complications
0.000 0.736 0.264
E13.3 With ophthalmic complications
0.000 0.736 0.264
E13.2 With renal complications
0.000 0.736 0.264
E13.1 With ketoacidosis
0.000 0.736 0.264
E13.0 With coma
0.000 0.736 0.264
E11 Non-insulin-dependent diabetes mellitus
0.000 0.741 0.259
K90.3 Pancreatic steatorrhoea
0.000 0.747 0.252
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.747 0.252
K90.1 Tropical sprue
0.000 0.747 0.252
E14.9 Without complications
0.000 0.748 0.252
E03 Other hypothyroidism
0.235 0.749 0.015
L40.9 Psoriasis, unspecified
0.000 0.753 0.247
E16.2 Hypoglycaemia, unspecified
0.000 0.755 0.245
K90.9 Intestinal malabsorption, unspecified
0.000 0.756 0.244
E11.3 With ophthalmic complications
0.000 0.761 0.239
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.762 0.237
E16 Other disorders of pancreatic internal secretion
0.000 0.762 0.238
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.001 0.763 0.236
K90.8 Other intestinal malabsorption
0.000 0.764 0.236
E11.5 With peripheral circulatory complications
0.000 0.773 0.226
E27.1 Primary adrenocortical insufficiency
0.000 0.776 0.224
E13.9 Without complications
0.000 0.783 0.217
E27 Other disorders of adrenal gland
0.000 0.784 0.216
E20-E35 Disorders of other endocrine glands
0.000 0.788 0.212
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.792 0.208
E11.1 With ketoacidosis
0.000 0.794 0.205
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.190 0.801 0.009
E00-E07 Disorders of thyroid gland
0.136 0.806 0.058
E11.8 With unspecified complications
0.000 0.811 0.189
E11.7 With multiple complications
0.000 0.814 0.186
E27.2 Addisonian crisis
0.000 0.818 0.182
L40 Psoriasis
0.000 0.818 0.182
E03.5 Myxoedema coma
0.169 0.820 0.011
E03.4 Atrophy of thyroid (acquired)
0.169 0.820 0.011
E03.3 Postinfectious hypothyroidism
0.169 0.820 0.011
E03.1 Congenital hypothyroidism without goitre
0.169 0.820 0.011
E03.0 Congenital hypothyroidism with diffuse goitre
0.169 0.820 0.011
E20 Hypoparathyroidism
0.000 0.823 0.177
E34 Other endocrine disorders
0.000 0.824 0.176
E16.1 Other hypoglycaemia
0.000 0.828 0.172
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.829 0.170
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.829 0.170
E16.4 Abnormal secretion of gastrin
0.000 0.829 0.170
E16.3 Increased secretion of glucagon
0.000 0.829 0.170
E15 Nondiabetic hypoglycaemic coma
0.001 0.830 0.170
D86.9 Sarcoidosis, unspecified
0.000 0.831 0.169
L40.0 Psoriasis vulgaris
0.000 0.832 0.168
E11.4 With neurological complications
0.000 0.834 0.166
E03.8 Other specified hypothyroidism
0.153 0.837 0.010
J33.0 Polyp of nasal cavity
0.000 0.838 0.162
E07 Other disorders of thyroid
0.135 0.838 0.026
D86 Sarcoidosis
0.000 0.841 0.159
E40-E46 Malnutrition
0.001 0.843 0.157
E22 Hyperfunction of pituitary gland
0.000 0.845 0.155
E27.5 Adrenomedullary hyperfunction
0.000 0.845 0.155
E27.0 Other adrenocortical overactivity
0.000 0.845 0.155
E34.9 Endocrine disorder, unspecified
0.000 0.845 0.155
E20.9 Hypoparathyroidism, unspecified
0.000 0.847 0.152
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.848 0.152
E32 Diseases of thymus
0.000 0.848 0.152
E31 Polyglandular dysfunction
0.000 0.848 0.152
E30 Disorders of puberty, not elsewhere classified
0.000 0.848 0.152
E25 Adrenogenital disorders
0.000 0.848 0.152
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.850 0.150
E27.8 Other specified disorders of adrenal gland
0.000 0.850 0.149
M45-M49 Spondylopathies
0.148 0.852 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.853 0.146
D80-D89 Certain disorders involving the immune mechanism
0.000 0.857 0.143
E11.6 With other specified complications
0.000 0.859 0.141
E24 Cushing's syndrome
0.000 0.860 0.140
E07.9 Disorder of thyroid, unspecified
0.138 0.860 0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.098 0.861 0.042
E00 Congenital iodine-deficiency syndrome
0.098 0.861 0.042
L40.1 Generalised pustular psoriasis
0.000 0.861 0.139
E02 Subclinical iodine-deficiency hypothyroidism
0.098 0.863 0.040
L40.5 Arthropathic psoriasis
0.000 0.864 0.136
D86.1 Sarcoidosis of lymph nodes
0.000 0.864 0.135
E34.0 Carcinoid syndrome
0.000 0.865 0.135
E16.0 Drug-induced hypoglycaemia without coma
0.001 0.869 0.131
D50-D53 Nutritional anaemias
0.000 0.869 0.131
L40.4 Guttate psoriasis
0.000 0.869 0.131
L40.3 Pustulosis palmaris et plantaris
0.000 0.869 0.131
L40.2 Acrodermatitis continua
0.000 0.869 0.131
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.870 0.130
E29 Testicular dysfunction
0.000 0.870 0.129
D80 Immunodeficiency with predominantly antibody defects
0.000 0.872 0.128
D50 Iron deficiency anaemia
0.000 0.872 0.128
E20.8 Other hypoparathyroidism
0.000 0.873 0.127
E20.1 Pseudohypoparathyroidism
0.000 0.873 0.127
E20.0 Idiopathic hypoparathyroidism
0.000 0.873 0.127
E34.5 Androgen resistance syndrome
0.000 0.874 0.126
E34.4 Constitutional tall stature
0.000 0.874 0.126
E34.3 Short stature, not elsewhere classified
0.000 0.874 0.126
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.874 0.126
E34.1 Other hypersecretion of intestinal hormones
0.000 0.874 0.126
E27.9 Disorder of adrenal gland, unspecified
0.000 0.874 0.126
M46 Other inflammatory spondylopathies
0.125 0.875 0.000
D86.3 Sarcoidosis of skin
0.000 0.877 0.123
E06 Thyroiditis
0.096 0.877 0.026
D50.9 Iron deficiency anaemia, unspecified
0.000 0.878 0.122
D50.8 Other iron deficiency anaemias
0.000 0.878 0.122
D51 Vitamin B12 deficiency anaemia
0.000 0.879 0.121
D86.0 Sarcoidosis of lung
0.000 0.880 0.120
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.881 0.119
E22.0 Acromegaly and pituitary gigantism
0.000 0.882 0.118
E07.1 Dyshormogenetic goitre
0.097 0.884 0.019
E07.0 Hypersecretion of calcitonin
0.097 0.884 0.019
D60-D64 Aplastic and other anaemias
0.000 0.885 0.115
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.886 0.114
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.887 0.112
E45 Retarded development following protein-energy malnutrition
0.001 0.887 0.112
E43 Unspecified severe protein-energy malnutrition
0.001 0.887 0.112
E42 Marasmic kwashiorkor
0.001 0.887 0.112
E41 Nutritional marasmus
0.001 0.887 0.112
E40 Kwashiorkor
0.001 0.887 0.112
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.888 0.111
E22.8 Other hyperfunction of pituitary gland
0.000 0.888 0.111
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.889 0.111
M46.4 Discitis, unspecified
0.111 0.889 0.000
D83 Common variable immunodeficiency
0.000 0.889 0.111
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.891 0.109
E30.9 Disorder of puberty, unspecified
0.000 0.891 0.109
E30.8 Other disorders of puberty
0.000 0.891 0.109
E30.1 Precocious puberty
0.000 0.891 0.109
E30.0 Delayed puberty
0.000 0.891 0.109
E31.9 Polyglandular dysfunction, unspecified
0.000 0.891 0.109
E31.8 Other polyglandular dysfunction
0.000 0.891 0.109
E31.1 Polyglandular hyperfunction
0.000 0.891 0.109
E31.0 Autoimmune polyglandular failure
0.000 0.891 0.109
E32.9 Disease of thymus, unspecified
0.000 0.891 0.109
E32.8 Other diseases of thymus
0.000 0.891 0.109
E32.1 Abscess of thymus
0.000 0.891 0.109
E32.0 Persistent hyperplasia of thymus
0.000 0.891 0.109
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.891 0.109
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.891 0.109
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.891 0.109
E25.9 Adrenogenital disorder, unspecified
0.000 0.891 0.109
E25.8 Other adrenogenital disorders
0.000 0.891 0.109
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.891 0.109
E22.1 Hyperprolactinaemia
0.000 0.892 0.108
E26 Hyperaldosteronism
0.000 0.894 0.106
D64 Other anaemias
0.000 0.894 0.106
L40.8 Other psoriasis
0.000 0.894 0.105
D82 Immunodeficiency associated with other major defects
0.000 0.897 0.103
D81 Combined immunodeficiencies
0.000 0.897 0.103
E11.0 With coma
0.001 0.898 0.102
D64.9 Anaemia, unspecified
0.000 0.898 0.102
M48 Other spondylopathies
0.102 0.898 0.000
D53 Other nutritional anaemias
0.000 0.898 0.102
E07.8 Other specified disorders of thyroid
0.082 0.898 0.019
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.899 0.101
E34.8 Other specified endocrine disorders
0.000 0.899 0.101
E24.8 Other Cushing's syndrome
0.000 0.899 0.101
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.899 0.101
E24.3 Ectopic ACTH syndrome
0.000 0.899 0.101
E24.1 Nelson's syndrome
0.000 0.899 0.101
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.900 0.100
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.070 0.900 0.030
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.070 0.900 0.030
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.070 0.900 0.030
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.070 0.900 0.030
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.070 0.900 0.030
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.070 0.900 0.030
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.070 0.900 0.030
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.070 0.900 0.030
E46 Unspecified protein-energy malnutrition
0.000 0.901 0.099
E24.9 Cushing's syndrome, unspecified
0.000 0.901 0.099
D86.8 Sarcoidosis of other and combined sites
0.000 0.902 0.098
K90-K93 Other diseases of the digestive system
0.000 0.902 0.098
E24.2 Drug-induced Cushing's syndrome
0.000 0.903 0.097
D62 Acute posthaemorrhagic anaemia
0.000 0.903 0.097
M46.46 Discitis, unspecified (Lumbar region)
0.097 0.903 0.000
M49 Spondylopathies in diseases classified elsewhere
0.096 0.904 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.904 0.095
E28 Ovarian dysfunction
0.000 0.905 0.095
E06.1 Subacute thyroiditis
0.079 0.906 0.015
E29.9 Testicular dysfunction, unspecified
0.000 0.907 0.093
E29.8 Other testicular dysfunction
0.000 0.907 0.093
E29.0 Testicular hyperfunction
0.000 0.907 0.093
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.908 0.092
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.908 0.092
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.908 0.092
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.908 0.092
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.908 0.092
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.908 0.092
E06.5 Other chronic thyroiditis
0.075 0.908 0.017
D50.1 Sideropenic dysphagia
0.000 0.908 0.092
M46.2 Osteomyelitis of vertebra
0.091 0.908 0.000
M46.8 Other specified inflammatory spondylopathies
0.090 0.910 0.000
M46.5 Other infective spondylopathies
0.090 0.910 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.090 0.910 0.000
M46.0 Spinal enthesopathy
0.090 0.910 0.000
D84 Other immunodeficiencies
0.000 0.910 0.089
D55-D59 Haemolytic anaemias
0.000 0.911 0.089
E11.2 With renal complications
0.000 0.911 0.088
E06.4 Drug-induced thyroiditis
0.069 0.912 0.019
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.069 0.912 0.019
E06.0 Acute thyroiditis
0.069 0.912 0.019
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.912 0.088
D83.9 Common variable immunodeficiency, unspecified
0.000 0.912 0.088
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.913 0.087
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.913 0.087
D51.2 Transcobalamin II deficiency
0.000 0.913 0.087
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.913 0.087
E50-E64 Other nutritional deficiencies
0.001 0.913 0.086
M46.42 Discitis, unspecified (Cervical region)
0.087 0.913 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.040 0.914 0.046
M46.1 Sacro-iliitis, not elsewhere classified
0.086 0.914 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.085 0.915 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.083 0.917 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.917 0.082
K91.3 Postoperative intestinal obstruction
0.000 0.917 0.082
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.918 0.082
E44.1 Mild protein-energy malnutrition
0.001 0.919 0.081
E44.0 Moderate protein-energy malnutrition
0.001 0.919 0.081
D53.9 Nutritional anaemia, unspecified
0.000 0.919 0.081
M48.9 Spondylopathy, unspecified
0.081 0.919 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.080 0.920 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.080 0.920 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.080 0.920 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.080 0.920 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.080 0.920 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.080 0.920 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.080 0.920 0.000
D83.8 Other common variable immunodeficiencies
0.000 0.920 0.079
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.920 0.079
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.920 0.079
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.920 0.079
E06.9 Thyroiditis, unspecified
0.061 0.920 0.019
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.921 0.079
M48.8 Other specified spondylopathies
0.078 0.922 0.000
K76.8 Other specified diseases of liver
0.000 0.922 0.078
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.923 0.076
E26.8 Other hyperaldosteronism
0.000 0.924 0.076
E26.1 Secondary hyperaldosteronism
0.000 0.924 0.076
D64.4 Congenital dyserythropoietic anaemia
0.000 0.924 0.076
D64.3 Other sideroblastic anaemias
0.000 0.924 0.076
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.924 0.076
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.924 0.076
D64.0 Hereditary sideroblastic anaemia
0.000 0.924 0.076
D59 Acquired haemolytic anaemia
0.000 0.925 0.075
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.925 0.075
D81.9 Combined immunodeficiency, unspecified
0.000 0.926 0.074
D81.8 Other combined immunodeficiencies
0.000 0.926 0.074
D81.7 Major histocompatibility complex class II deficiency
0.000 0.926 0.074
D81.6 Major histocompatibility complex class I deficiency
0.000 0.926 0.074
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.926 0.074
D81.4 Nezelof's syndrome
0.000 0.926 0.074
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.926 0.074
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.926 0.074
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.926 0.074
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.926 0.074
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.926 0.074
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.926 0.074
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.926 0.074
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.926 0.074
D82.2 Immunodeficiency with short-limbed stature
0.000 0.926 0.074
D82.1 Di George's syndrome
0.000 0.926 0.074
D82.0 Wiskott-Aldrich syndrome
0.000 0.926 0.074
M48.4 Fatigue fracture of vertebra
0.073 0.926 0.000
M48.3 Traumatic spondylopathy
0.073 0.926 0.000
M48.2 Kissing spine
0.073 0.926 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.073 0.926 0.000
D53.8 Other specified nutritional anaemias
0.000 0.927 0.073
D53.2 Scorbutic anaemia
0.000 0.927 0.073
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.927 0.073
D53.0 Protein deficiency anaemia
0.000 0.927 0.073
K70-K77 Diseases of liver
0.000 0.927 0.073
D52 Folate deficiency anaemia
0.000 0.928 0.072
K76 Other diseases of liver
0.000 0.928 0.072
M48.5 Collapsed vertebra, not elsewhere classified
0.071 0.928 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.929 0.070
E29.1 Testicular hypofunction
0.000 0.929 0.070
K73 Chronic hepatitis, not elsewhere classified
0.000 0.930 0.070
K72 Hepatic failure, not elsewhere classified
0.000 0.930 0.070
K72.9 Hepatic failure, unspecified
0.000 0.930 0.070
M49.8 Spondylopathy in other diseases classified elsewhere
0.069 0.931 0.000
M49.4 Neuropathic spondylopathy
0.069 0.931 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.069 0.931 0.000
M49.2 Enterobacterial spondylitis
0.069 0.931 0.000
M49.1 Brucella spondylitis
0.069 0.931 0.000
M49.0 Tuberculosis of spine
0.069 0.931 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.931 0.068
E28.8 Other ovarian dysfunction
0.000 0.931 0.068
E28.1 Androgen excess
0.000 0.931 0.068
E28.0 Oestrogen excess
0.000 0.931 0.068
E65-E68 Obesity and other hyperalimentation
0.001 0.932 0.067
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.067 0.932 0.000
E06.3 Autoimmune thyroiditis
0.052 0.932 0.015
K73.9 Chronic hepatitis, unspecified
0.000 0.934 0.066
K75 Other inflammatory liver diseases
0.000 0.934 0.066
K91.5 Postcholecystectomy syndrome
0.000 0.934 0.066
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.066 0.934 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.066 0.934 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.066 0.934 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.066 0.934 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.066 0.934 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.066 0.934 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.066 0.934 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.066 0.934 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.066 0.934 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.066 0.934 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.935 0.065
M46.09 Spinal enthesopathy (Site unspecified)
0.064 0.935 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.064 0.935 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.064 0.935 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.064 0.935 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.064 0.935 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.064 0.935 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.064 0.935 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.064 0.935 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.064 0.935 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.064 0.935 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.064 0.935 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.064 0.935 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.064 0.935 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.064 0.935 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.064 0.935 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.064 0.935 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.064 0.935 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.064 0.935 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.064 0.935 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.064 0.935 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.064 0.935 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.064 0.935 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.064 0.935 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.064 0.935 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.064 0.935 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.064 0.935 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.064 0.935 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.064 0.935 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.064 0.935 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.064 0.935 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.064 0.935 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.064 0.935 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.064 0.935 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.064 0.935 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.064 0.935 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.064 0.935 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.064 0.935 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.064 0.935 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.064 0.935 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.064 0.935 0.000
D84.8 Other specified immunodeficiencies
0.000 0.935 0.064
D84.1 Defects in the complement system
0.000 0.935 0.064
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.935 0.064
D64.8 Other specified anaemias
0.000 0.936 0.064
D57 Sickle-cell disorders
0.000 0.936 0.064
D55 Anaemia due to enzyme disorders
0.000 0.936 0.064
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.064 0.936 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.937 0.062
E63 Other nutritional deficiencies
0.001 0.937 0.062
E50 Vitamin A deficiency
0.001 0.937 0.062
E60 Dietary zinc deficiency
0.001 0.937 0.062
E59 Dietary selenium deficiency
0.001 0.937 0.062
E54 Ascorbic acid deficiency
0.001 0.937 0.062
E52 Niacin deficiency [pellagra]
0.001 0.937 0.062
M48.99 Spondylopathy, unspecified (Site unspecified)
0.062 0.938 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.062 0.938 0.000
E05.5 Thyroid crisis or storm
0.029 0.938 0.033
E05.4 Thyrotoxicosis factitia
0.029 0.938 0.033
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.029 0.938 0.033
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.029 0.938 0.033
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.062 0.938 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.062 0.938 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.062 0.938 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.062 0.938 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.062 0.938 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.062 0.938 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.062 0.938 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.062 0.938 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.062 0.938 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.939 0.061
E51 Thiamine deficiency
0.001 0.939 0.061
K75.8 Other specified inflammatory liver diseases
0.000 0.939 0.061
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.939 0.061
D69 Purpura and other haemorrhagic conditions
0.000 0.939 0.061
E26.0 Primary hyperaldosteronism
0.001 0.939 0.061
M48.86 Other specified spondylopathies (Lumbar region)
0.061 0.939 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.061 0.939 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.061 0.939 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.061 0.939 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.061 0.939 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.061 0.939 0.000
D61 Other aplastic anaemias
0.000 0.939 0.061
E53 Deficiency of other B group vitamins
0.000 0.939 0.060
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.940 0.060
D59.1 Other autoimmune haemolytic anaemias
0.000 0.940 0.060
E05.8 Other thyrotoxicosis
0.030 0.940 0.030
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.940 0.059
D60.8 Other acquired pure red cell aplasias
0.000 0.940 0.059
D60.1 Transient acquired pure red cell aplasia
0.000 0.940 0.059
D60.0 Chronic acquired pure red cell aplasia
0.000 0.940 0.059
K75.4 Autoimmune hepatitis
0.000 0.941 0.059
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.941 0.059
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.941 0.059
D66 Hereditary factor VIII deficiency
0.000 0.941 0.059
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.058 0.941 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.058 0.941 0.000
K76.6 Portal hypertension
0.000 0.942 0.058
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.058 0.942 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.058 0.942 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.058 0.942 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.058 0.942 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.058 0.942 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.058 0.942 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.058 0.942 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.058 0.942 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.058 0.942 0.000
K70 Alcoholic liver disease
0.000 0.942 0.058
E23 Hypofunction and other disorders of pituitary gland
0.000 0.942 0.057
E56 Other vitamin deficiencies
0.001 0.943 0.057
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.943 0.057
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.057 0.943 0.000
D67 Hereditary factor IX deficiency
0.000 0.943 0.057
M48.87 Other specified spondylopathies (Lumbosacral region)
0.057 0.943 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.056 0.943 0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.056 0.943 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.056 0.943 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.056 0.943 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.056 0.943 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.056 0.943 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.056 0.943 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.056 0.943 0.000
K76.7 Hepatorenal syndrome
0.000 0.944 0.056
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.056 0.944 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.944 0.055
E04 Other non-toxic goitre
0.011 0.945 0.044
J33 Nasal polyp
0.000 0.945 0.055
E58 Dietary calcium deficiency
0.001 0.945 0.054
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.946 0.054
D59.8 Other acquired haemolytic anaemias
0.000 0.946 0.054
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.946 0.054
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.946 0.054
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.946 0.054
D59.3 Haemolytic-uraemic syndrome
0.000 0.946 0.054
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.946 0.054
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.946 0.054
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.946 0.054
D69.5 Secondary thrombocytopenia
0.000 0.946 0.054
D58 Other hereditary haemolytic anaemias
0.000 0.946 0.054
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.033 0.946 0.020
K91.1 Postgastric surgery syndromes
0.000 0.946 0.054
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.053 0.946 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.053 0.947 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.053 0.947 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.053 0.947 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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