TreeWAS – Variant ID: rs2524084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
J33.0 Polyp of nasal cavity	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
H36 Retinal disorders in diseases classified elsewhere	0.999	0.001	0.000
E14.3 With ophthalmic complications	0.999	0.001	0.000
H30-H36 Disorders of choroid and retina	0.999	0.001	0.000
M35.0 Sicca syndrome [Sjogren]	0.999	0.001	0.000
Chapter VIII Diseases of the ear and mastoid process	0.998	0.002	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.998	0.002	0.000
Chapter VII Diseases of the eye and adnexa	0.998	0.002	0.000
E14.9 Without complications	0.997	0.003	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.997	0.003	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004	0.000
E10.2 With renal complications	0.994	0.006	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.990	0.010	0.000
H60-H62 Diseases of external ear	0.990	0.010	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.990	0.010	0.000
E10.4 With neurological complications	0.988	0.012	0.000
D80-D89 Certain disorders involving the immune mechanism	0.986	0.014	0.000
J45.9 Asthma, unspecified	0.985	0.015	0.000
E11.5 With peripheral circulatory complications	0.983	0.017	0.000
D86 Sarcoidosis	0.982	0.018	0.000
M34 Systemic sclerosis	0.980	0.020	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.977	0.023	0.000
J45 Asthma	0.977	0.023	0.000
D86.9 Sarcoidosis, unspecified	0.976	0.024	0.000
E20-E35 Disorders of other endocrine glands	0.976	0.024	0.000
H90-H95 Other disorders of ear	0.975	0.025	0.000
K90 Intestinal malabsorption	0.974	0.026	0.000
M10 Gout	0.970	0.030	0.000
H53-H54 Visual disturbances and blindness	0.970	0.030	0.000
H60 Otitis externa	0.969	0.031	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.969	0.031	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.960	0.040	0.000
E11.3 With ophthalmic complications	0.958	0.042	0.000
J40-J47 Chronic lower respiratory diseases	0.957	0.043	0.000
R31 Unspecified haematuria	0.000	0.045	0.955
Chapter X Diseases of the respiratory system	0.952	0.048	0.000
J33.8 Other polyp of sinus	0.949	0.051	0.000
E27 Other disorders of adrenal gland	0.947	0.053	0.000
K90.9 Intestinal malabsorption, unspecified	0.946	0.054	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.946	0.054	0.000
D60-D64 Aplastic and other anaemias	0.946	0.054	0.000
M06.3 Rheumatoid nodule	0.946	0.054	0.000
E27.1 Primary adrenocortical insufficiency	0.937	0.063	0.000
E10.5 With peripheral circulatory complications	0.933	0.067	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.931	0.069	0.000
J30-J39 Other diseases of upper respiratory tract	0.930	0.070	0.000
D61 Other aplastic anaemias	0.929	0.071	0.000
H60.1 Cellulitis of external ear	0.928	0.072	0.000
E11.1 With ketoacidosis	0.925	0.075	0.000
E10.0 With coma	0.925	0.075	0.000
H92 Otalgia and effusion of ear	0.921	0.079	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.920	0.080	0.000
H90 Conductive and sensorineural hearing loss	0.917	0.083	0.000
M10.9 Gout, unspecified	0.916	0.084	0.000
M34.9 Systemic sclerosis, unspecified	0.915	0.085	0.000
M32 Systemic lupus erythematosus	0.906	0.094	0.000
H61 Other disorders of external ear	0.905	0.095	0.000
H92.1 Otorrhoea	0.903	0.097	0.000
H53 Visual disturbances	0.902	0.098	0.000
M60-M63 Disorders of muscles	0.900	0.100	0.000
D61.9 Aplastic anaemia, unspecified	0.898	0.102	0.000
L90 Atrophic disorders of skin	0.895	0.105	0.000
M06.0 Seronegative rheumatoid arthritis	0.894	0.106	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.893	0.107	0.000
E11.9 Without complications	0.891	0.109	0.000
H54 Blindness and low vision	0.890	0.110	0.000
E14.8 With unspecified complications	0.889	0.111	0.000
J44 Other chronic obstructive pulmonary disease	0.887	0.113	0.000
L94 Other localised connective tissue disorders	0.887	0.113	0.000
L20-L30 Dermatitis and eczema	0.885	0.115	0.000
M80-M85 Disorders of bone density and structure	0.884	0.116	0.000
M06.4 Inflammatory polyarthropathy	0.883	0.117	0.000
E10.6 With other specified complications	0.883	0.117	0.000
J46 Status asthmaticus	0.882	0.118	0.000
L90.0 Lichen sclerosus et atrophicus	0.882	0.118	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.881	0.119	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.881	0.119	0.000
M80 Osteoporosis with pathological fracture	0.878	0.122	0.000
E14.6 With other specified complications	0.876	0.124	0.000
E29 Testicular dysfunction	0.876	0.124	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.873	0.127	0.000
H53.2 Diplopia	0.868	0.132	0.000
H60.3 Other infective otitis externa	0.867	0.133	0.000
E14.1 With ketoacidosis	0.866	0.134	0.000
H60.9 Otitis externa, unspecified	0.864	0.136	0.000
M10.0 Idiopathic gout	0.862	0.138	0.000
H30 Chorioretinal inflammation	0.861	0.139	0.000
M65-M68 Disorders of synovium and tendon	0.859	0.141	0.000
E10.8 With unspecified complications	0.858	0.142	0.000
L10-L14 Bullous disorders	0.858	0.142	0.000
M21 Other acquired deformities of limbs	0.856	0.144	0.000
E06 Thyroiditis	0.855	0.145	0.000
J45.0 Predominantly allergic asthma	0.855	0.145	0.000
H61.2 Impacted cerumen	0.854	0.146	0.000
M06.34 Rheumatoid nodule (Hand)	0.853	0.147	0.000
L40-L45 Papulosquamous disorders	0.796	0.149	0.055
E50-E64 Other nutritional deficiencies	0.851	0.149	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.850	0.150	0.000
D55-D59 Haemolytic anaemias	0.845	0.155	0.000
H31 Other disorders of choroid	0.845	0.155	0.000
M34.1 CR(E)ST syndrome	0.845	0.155	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.844	0.156	0.000
H90.2 Conductive hearing loss, unspecified	0.842	0.158	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.838	0.162	0.000
L28 Lichen simplex chronicus and prurigo	0.838	0.162	0.000
D86.8 Sarcoidosis of other and combined sites	0.838	0.162	0.000
E83.1 Disorders of iron metabolism	0.000	0.163	0.837
M32.1 Systemic lupus erythematosus with organ or system involvement	0.833	0.166	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.832	0.168	0.000
M35.1 Other overlap syndromes	0.829	0.171	0.000
E11.8 With unspecified complications	0.828	0.172	0.000
M14 Arthropathies in other diseases classified elsewhere	0.826	0.174	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.826	0.174	0.000
D61.1 Drug-induced aplastic anaemia	0.824	0.176	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.824	0.176	0.000
L84 Corns and callosities	0.823	0.177	0.000
H54.9 Unspecified visual impairment (binocular)	0.822	0.178	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.821	0.179	0.000
M06.8 Other specified rheumatoid arthritis	0.820	0.180	0.000
E14.2 Withrenal complications	0.819	0.181	0.000
M34.8 Other forms of systemic sclerosis	0.819	0.181	0.000
L81 Other disorders of pigmentation	0.818	0.182	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.817	0.183	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.817	0.183	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.817	0.183	0.000
E11.7 With multiple complications	0.814	0.186	0.000
E10.7 With multiple complications	0.814	0.186	0.000
H90.3 Sensorineural hearing loss, bilateral	0.810	0.190	0.000
M10.94 Gout, unspecified (Hand)	0.808	0.192	0.000
L94.0 Localised scleroderma [morphea]	0.807	0.193	0.000
L80 Vitiligo	0.806	0.194	0.000
E29.1 Testicular hypofunction	0.804	0.196	0.000
H35 Other retinal disorders	0.804	0.196	0.000
M12 Other specific arthropathies	0.801	0.199	0.000
H95.1 Other disorders following mastoidectomy	0.801	0.199	0.000
M66 Spontaneous rupture of synovium and tendon	0.798	0.202	0.000
L29 Pruritus	0.798	0.202	0.000
D86.1 Sarcoidosis of lymph nodes	0.795	0.205	0.000
J45.1 Nonallergic asthma	0.793	0.207	0.000
E40-E46 Malnutrition	0.792	0.208	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.788	0.212	0.000
M00-M03 Infectious arthropathies	0.786	0.214	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.784	0.216	0.000
H35.8 Other specified retinal disorders	0.782	0.218	0.000
H35.4 Peripheral retinal degeneration	0.782	0.218	0.000
L43 Lichen planus	0.763	0.222	0.015
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.776	0.224	0.000
M35.2 Behcet's disease	0.776	0.224	0.000
J33.1 Polypoid sinus degeneration	0.775	0.224	0.000
E24 Cushing's syndrome	0.775	0.225	0.000
L28.0 Lichen simplex chronicus	0.774	0.226	0.000
M21.0 Valgus deformity, not elsewhere classified	0.774	0.226	0.000
E05.8 Other thyrotoxicosis	0.774	0.226	0.000
E22 Hyperfunction of pituitary gland	0.773	0.227	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.772	0.228	0.000
H61.1 Non-infective disorders of pinna	0.772	0.228	0.000
L81.9 Disorder of pigmentation, unspecified	0.771	0.229	0.000
M25 Other joint disorders, not elsewhere classified	0.768	0.232	0.000
M60 Myositis	0.768	0.232	0.000
M34.0 Progressive systemic sclerosis	0.767	0.233	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.767	0.233	0.000
M05.8 Other seropositive rheumatoid arthritis	0.765	0.235	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.765	0.235	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.765	0.235	0.000
M62 Other disorders of muscle	0.762	0.238	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.762	0.238	0.000
L50-L54 Urticaria and erythema	0.761	0.239	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.761	0.239	0.000
E34 Other endocrine disorders	0.761	0.239	0.000
H25-H28 Disorders of lens	0.761	0.239	0.000
J38.1 Polyp of vocal cord and larynx	0.757	0.243	0.000
L13 Other bullous disorders	0.754	0.246	0.000
J38.2 Nodules of vocal cords	0.751	0.249	0.000
E11.0 With coma	0.750	0.250	0.000
L83 Acanthosis nigricans	0.750	0.250	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.748	0.252	0.000
H34 Retinal vascular occlusions	0.748	0.252	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.747	0.253	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.746	0.254	0.000
H65-H75 Diseases of middle ear and mastoid	0.744	0.256	0.000
M30 Polyarteritis nodosa and related conditions	0.743	0.257	0.000
M25.9 Joint disorder, unspecified	0.741	0.259	0.000
M31 Other necrotising vasculopathies	0.740	0.260	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.740	0.260	0.000
D59 Acquired haemolytic anaemia	0.740	0.260	0.000
K90.8 Other intestinal malabsorption	0.739	0.261	0.000
M08 Juvenile arthritis	0.738	0.262	0.000
E11.4 With neurological complications	0.738	0.262	0.000
K90-K93 Other diseases of the digestive system	0.737	0.263	0.000
D83 Common variable immunodeficiency	0.737	0.263	0.000
E13 Other specified diabetes mellitus	0.736	0.264	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.735	0.265	0.000
D50-D53 Nutritional anaemias	0.734	0.266	0.000
D80 Immunodeficiency with predominantly antibody defects	0.733	0.267	0.000
E31 Polyglandular dysfunction	0.731	0.269	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.729	0.271	0.000
E11.6 With other specified complications	0.729	0.271	0.000
L85 Other epidermal thickening	0.729	0.271	0.000
M07 Psoriatic and enteropathic arthropathies	0.729	0.271	0.000
E14.5 With peripheral circulatory complications	0.727	0.273	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.726	0.274	0.000
M10.06 Idiopathic gout (Lower leg)	0.726	0.274	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.725	0.275	0.000
H54.7 Unspecified visual loss	0.723	0.277	0.000
H60.2 Malignant otitis externa	0.720	0.279	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.719	0.281	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.719	0.281	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.716	0.284	0.000
Chapter XI Diseases of the digestive system	0.716	0.284	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.716	0.284	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.715	0.285	0.000
H53.5 Colour vision deficiencies	0.714	0.286	0.000
D82 Immunodeficiency associated with other major defects	0.713	0.287	0.000
M10.04 Idiopathic gout (Hand)	0.713	0.287	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.712	0.288	0.000
L28.1 Prurigo nodularis	0.712	0.288	0.000
L90.9 Atrophic disorder of skin, unspecified	0.712	0.288	0.000
K75.4 Autoimmune hepatitis	0.711	0.289	0.000
H43-H45 Disorders of vitreous body and globe	0.711	0.289	0.000
L43.9 Lichen planus, unspecified	0.710	0.289	0.001
M11 Other crystal arthropathies	0.710	0.290	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.710	0.290	0.000
H54.0 Blindness, both eyes	0.710	0.290	0.000
M24 Other specific joint derangements	0.708	0.292	0.000
H31.0 Chorioretinal scars	0.707	0.293	0.000
D81 Combined immunodeficiencies	0.707	0.293	0.000
E06.9 Thyroiditis, unspecified	0.707	0.293	0.000
K75 Other inflammatory liver diseases	0.707	0.293	0.000
K70-K77 Diseases of liver	0.706	0.294	0.000
H30.2 Posterior cyclitis	0.706	0.294	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.705	0.295	0.000
H30.9 Chorioretinal inflammation, unspecified	0.705	0.295	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.704	0.296	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.703	0.297	0.000
M21.8 Other specified acquired deformities of limbs	0.701	0.299	0.000
M05.1 Rheumatoid lung disease	0.701	0.299	0.000
L25 Unspecified contact dermatitis	0.700	0.300	0.000
L94.2 Calcinosis cutis	0.700	0.300	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.699	0.300	0.000
E32 Diseases of thymus	0.699	0.300	0.000
E30 Disorders of puberty, not elsewhere classified	0.699	0.300	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.699	0.301	0.000
K90.3 Pancreatic steatorrhoea	0.698	0.301	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.698	0.301	0.000
K90.1 Tropical sprue	0.698	0.301	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.698	0.302	0.000
D64 Other anaemias	0.698	0.302	0.000
L94.9 Localised connective tissue disorder, unspecified	0.697	0.303	0.000
H90.0 Conductive hearing loss, bilateral	0.697	0.303	0.000
J45.8 Mixed asthma	0.696	0.304	0.000
M10.4 Other secondary gout	0.696	0.304	0.000
M10.3 Gout due to impairment of renal function	0.696	0.304	0.000
M10.2 Drug-induced gout	0.696	0.304	0.000
M10.1 Lead-induced gout	0.696	0.304	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.695	0.305	0.000
H74 Other disorders of middle ear and mastoid	0.694	0.306	0.000
E20 Hypoparathyroidism	0.693	0.307	0.000
L12 Pemphigoid	0.693	0.307	0.000
E55 Vitamin D deficiency	0.691	0.309	0.000
H54.6 Unqualified visual loss, one eye	0.689	0.311	0.000
H61.3 Acquired stenosis of external ear canal	0.689	0.311	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.688	0.312	0.000
M10.92 Gout, unspecified (Upper arm)	0.685	0.315	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.685	0.315	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.684	0.316	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.682	0.318	0.000
L85.9 Epidermal thickening, unspecified	0.681	0.319	0.000
E51 Thiamine deficiency	0.679	0.321	0.000
L13.0 Dermatitis herpetiformis	0.679	0.321	0.000
E27.5 Adrenomedullary hyperfunction	0.679	0.321	0.000
E27.0 Other adrenocortical overactivity	0.679	0.321	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.678	0.321	0.000
L87 Transepidermal elimination disorders	0.678	0.321	0.000
L86 Keratoderma in diseases classified elsewhere	0.678	0.321	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.678	0.322	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.678	0.322	0.000
M06.38 Rheumatoid nodule (Other)	0.678	0.322	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.678	0.322	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.678	0.322	0.000
M06.33 Rheumatoid nodule (Forearm)	0.678	0.322	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.678	0.322	0.000
E14.4 With neurological complications	0.677	0.323	0.000
L81.2 Freckles	0.677	0.323	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.677	0.323	0.000
D61.0 Constitutional aplastic anaemia	0.676	0.324	0.000
H26 Other cataract	0.676	0.324	0.000
M82 Osteoporosis in diseases classified elsewhere	0.676	0.324	0.000
M10.96 Gout, unspecified (Lower leg)	0.675	0.325	0.000
L43.8 Other lichen planus	0.668	0.326	0.006
M21.7 Unequal limb length (acquired)	0.673	0.327	0.000
L52 Erythema nodosum	0.672	0.328	0.000
H35.2 Other proliferative retinopathy	0.671	0.329	0.000
E25 Adrenogenital disorders	0.671	0.329	0.000
H54.2 Low vision, both eyes	0.670	0.330	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.670	0.330	0.000
M66.2 Spontaneous rupture of extensor tendons	0.670	0.330	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.668	0.331	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.668	0.332	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.668	0.332	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.667	0.333	0.000
M66.3 Spontaneous rupture of flexor tendons	0.667	0.333	0.000
H53.8 Other visual disturbances	0.667	0.333	0.000
H53.1 Subjective visual disturbances	0.667	0.333	0.000
D61.8 Other specified aplastic anaemias	0.666	0.334	0.000
D61.3 Idiopathic aplastic anaemia	0.666	0.334	0.000
D61.2 Aplastic anaemia due to other external agents	0.666	0.334	0.000
M10.02 Idiopathic gout (Upper arm)	0.666	0.334	0.000
D86.0 Sarcoidosis of lung	0.664	0.336	0.000
L29.0 Pruritus ani	0.663	0.337	0.000
E54 Ascorbic acid deficiency	0.662	0.338	0.000
M25.4 Effusion of joint	0.662	0.338	0.000
M31.3 Wegener's granulomatosis	0.661	0.339	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.660	0.340	0.000
H60.4 Cholesteatoma of external ear	0.660	0.340	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.659	0.341	0.000
E06.3 Autoimmune thyroiditis	0.658	0.341	0.000
M62.8 Other specified disorders of muscle	0.658	0.342	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.658	0.342	0.000
M10.98 Gout, unspecified (Other)	0.657	0.343	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.657	0.343	0.000
M10.91 Gout, unspecified (Shoulder region)	0.657	0.343	0.000
M91-M94 Chondropathies	0.655	0.345	0.000
H53.4 Visual field defects	0.655	0.345	0.000
L95.8 Other vasculitis limited to skin	0.654	0.346	0.000
H31.8 Other specified disorders of choroid	0.654	0.346	0.000
M83 Adult osteomalacia	0.653	0.347	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.653	0.347	0.000
M21.6 Other acquired deformities of ankle and foot	0.653	0.347	0.000
L26 Exfoliative dermatitis	0.652	0.348	0.000
H74.4 Polyp of middle ear	0.650	0.350	0.000
E23 Hypofunction and other disorders of pituitary gland	0.650	0.350	0.000
L29.9 Pruritus, unspecified	0.650	0.350	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.650	0.350	0.000
M32.8 Other forms of systemic lupus erythematosus	0.650	0.350	0.000
H31.3 Choroidal haemorrhage and rupture	0.649	0.351	0.000
E06.1 Subacute thyroiditis	0.648	0.352	0.000
M60.9 Myositis, unspecified	0.648	0.352	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.647	0.353	0.000
H53.6 Night blindness	0.646	0.354	0.000
H53.3 Other disorders of binocular vision	0.646	0.354	0.000
M10.00 Idiopathic gout (Multiple sites)	0.646	0.354	0.000
M67 Other disorders of synovium and tendon	0.646	0.354	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.645	0.355	0.000
M61 Calcification and ossification of muscle	0.645	0.355	0.000
L94.8 Other specified localised connective tissue disorders	0.645	0.355	0.000
E22.1 Hyperprolactinaemia	0.644	0.356	0.000
E46 Unspecified protein-energy malnutrition	0.644	0.356	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.644	0.356	0.000
M14.6 Neuropathic arthropathy	0.643	0.357	0.000
E22.0 Acromegaly and pituitary gigantism	0.642	0.358	0.000
H60.5 Acute otitis externa, non-infective	0.642	0.358	0.000
L90.6 Striae atrophicae	0.641	0.358	0.000
L90.4 Acrodermatitis chronica atrophicans	0.641	0.358	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.641	0.358	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.641	0.358	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.641	0.358	0.000
M21.9 Acquired deformity of limb, unspecified	0.641	0.359	0.000
H31.9 Disorder of choroid, unspecified	0.641	0.359	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.641	0.359	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.641	0.359	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.641	0.359	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.641	0.359	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.641	0.359	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.640	0.360	0.000
D86.3 Sarcoidosis of skin	0.639	0.361	0.000
M10.93 Gout, unspecified (Forearm)	0.639	0.361	0.000
H54.3 Unqualified visual loss, both eyes	0.638	0.362	0.000
H90.5 Sensorineural hearing loss, unspecified	0.638	0.362	0.000
M35.7 Hypermobility syndrome	0.637	0.363	0.000
M14.2 Diabetic arthropathy	0.637	0.363	0.000
H92.2 Otorrhagia	0.637	0.363	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.636	0.364	0.000
L94.6 Ainhum	0.636	0.364	0.000
L94.5 Poikiloderma vasculare atrophicans	0.636	0.364	0.000
L94.4 Gottron's papules	0.636	0.364	0.000
L94.3 Sclerodactyly	0.636	0.364	0.000
L94.1 Linear scleroderma	0.636	0.364	0.000
L24 Irritant contact dermatitis	0.635	0.365	0.000
L22 Diaper [napkin] dermatitis	0.635	0.365	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.634	0.366	0.000
E27.9 Disorder of adrenal gland, unspecified	0.633	0.367	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.633	0.367	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.633	0.367	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.633	0.367	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.633	0.367	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.633	0.367	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.633	0.367	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.633	0.367	0.000
E56 Other vitamin deficiencies	0.632	0.368	0.000
L29.8 Other pruritus	0.631	0.368	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.631	0.369	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.630	0.370	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.630	0.370	0.000
E61 Deficiency of other nutrient elements	0.630	0.370	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.630	0.370	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.629	0.371	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.629	0.371	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.629	0.371	0.000
L51 Erythema multiforme	0.629	0.371	0.000
E29.9 Testicular dysfunction, unspecified	0.628	0.372	0.000
E29.8 Other testicular dysfunction	0.628	0.372	0.000
E29.0 Testicular hyperfunction	0.628	0.372	0.000
L10 Pemphigus	0.627	0.373	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.626	0.374	0.000
L40 Psoriasis	0.084	0.374	0.542
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.626	0.374	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.626	0.374	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.626	0.374	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.626	0.374	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.626	0.374	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.626	0.374	0.000
D56 Thalassaemia	0.626	0.374	0.000
M10.99 Gout, unspecified (Site unspecified)	0.625	0.375	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.625	0.375	0.000
E11.2 With renal complications	0.625	0.375	0.000
D51 Vitamin B12 deficiency anaemia	0.625	0.375	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.625	0.375	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.623	0.377	0.000
H61.8 Other specified disorders of external ear	0.623	0.377	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.623	0.377	0.000
M66.0 Rupture of popliteal cyst	0.622	0.378	0.000
M02 Reactive arthropathies	0.621	0.379	0.000
M12.3 Palindromic rheumatism	0.621	0.379	0.000
K73 Chronic hepatitis, not elsewhere classified	0.619	0.381	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.619	0.381	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.618	0.382	0.000
M10.08 Idiopathic gout (Other)	0.618	0.382	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.618	0.382	0.000
M10.03 Idiopathic gout (Forearm)	0.618	0.382	0.000
M10.01 Idiopathic gout (Shoulder region)	0.618	0.382	0.000
J41 Simple and mucopurulent chronic bronchitis	0.618	0.382	0.000
H72 Perforation of tympanic membrane	0.618	0.382	0.000
Chapter IX Diseases of the circulatory system	0.617	0.383	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.617	0.383	0.000
H30.8 Other chorioretinal inflammations	0.617	0.383	0.000
H30.1 Disseminated chorioretinal inflammation	0.617	0.383	0.000
H30.0 Focal chorioretinal inflammation	0.617	0.383	0.000
E26 Hyperaldosteronism	0.617	0.383	0.000
H43 Disorders of vitreous body	0.616	0.384	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.616	0.384	0.000
H26.9 Cataract, unspecified	0.616	0.384	0.000
L14 Bullous disorders in diseases classified elsewhere	0.615	0.385	0.000
E24.0 Pituitary-dependent Cushing's disease	0.615	0.385	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.614	0.386	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations