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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2524222
log Bayes Factor = 56.3346
Chromosome 6   position 30,511,170  (GRCh37) Explore rs2524222 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.005 0.995
E00-E07 Disorders of thyroid gland
0.000 0.006 0.994
E10.1 With ketoacidosis
0.000 0.017 0.983
E10.3 With ophthalmic complications
0.000 0.018 0.982
E10.4 With neurological complications
0.000 0.030 0.970
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.034 0.966
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.041 0.959
L40.0 Psoriasis vulgaris
0.939 0.061 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.066 0.934
L40.8 Other psoriasis
0.928 0.072 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.086 0.914
E20-E35 Disorders of other endocrine glands
0.000 0.093 0.907
E10.5 With peripheral circulatory complications
0.000 0.101 0.899
E27 Other disorders of adrenal gland
0.000 0.103 0.897
E10.8 With unspecified complications
0.000 0.105 0.895
E27.1 Primary adrenocortical insufficiency
0.000 0.106 0.894
E10.0 With coma
0.000 0.109 0.891
E10.2 With renal complications
0.000 0.130 0.870
E10.6 With other specified complications
0.000 0.132 0.868
E13 Other specified diabetes mellitus
0.000 0.139 0.861
E20 Hypoparathyroidism
0.000 0.206 0.794
E50-E64 Other nutritional deficiencies
0.000 0.206 0.794
T36-T50 Poisoning by drugs, medicaments and biological substances
0.793 0.207 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.785 0.215 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.783 0.217 0.000
T43.2 Other and unspecified antidepressants
0.778 0.222 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.777 0.223 0.000
E13.9 Without complications
0.000 0.235 0.765
E05.8 Other thyrotoxicosis
0.000 0.247 0.753
E29 Testicular dysfunction
0.000 0.257 0.743
L40.1 Generalised pustular psoriasis
0.742 0.258 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.264 0.736
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.726 0.274 0.000
E10.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.714
E20.9 Hypoparathyroidism, unspecified
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.712
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.707 0.293 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.704 0.296 0.000
E40-E46 Malnutrition
0.000 0.305 0.695
E27.8 Other specified disorders of adrenal gland
0.000 0.306 0.694
E03 Other hypothyroidism
0.000 0.310 0.690
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.311 0.689
E15 Nondiabetic hypoglycaemic coma
0.000 0.312 0.688
E55 Vitamin D deficiency
0.000 0.315 0.685
T45.0 Antiallergic and antiemetic drugs
0.685 0.315 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.678 0.322 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.330 0.670
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.330 0.670
E16.4 Abnormal secretion of gastrin
0.000 0.330 0.670
E16.3 Increased secretion of glucagon
0.000 0.330 0.670
E27.9 Disorder of adrenal gland, unspecified
0.000 0.333 0.667
T42.1 Iminostilbenes
0.663 0.337 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.659 0.341 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.350 0.650
E32 Diseases of thymus
0.000 0.350 0.650
E31 Polyglandular dysfunction
0.000 0.350 0.650
E30 Disorders of puberty, not elsewhere classified
0.000 0.350 0.650
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
E28 Ovarian dysfunction
0.000 0.355 0.645
E27.5 Adrenomedullary hyperfunction
0.000 0.357 0.643
E27.0 Other adrenocortical overactivity
0.000 0.357 0.643
E24 Cushing's syndrome
0.000 0.358 0.642
E06 Thyroiditis
0.000 0.361 0.639
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.367 0.633
T46 Poisoning by agents primarily affecting the cardiovascular system
0.632 0.368 0.000
E14 Unspecified diabetes mellitus
0.000 0.373 0.627
E29.1 Testicular hypofunction
0.000 0.374 0.626
T43.3 Phenothiazine antipsychotics and neuroleptics
0.626 0.374 0.000
E16.1 Other hypoglycaemia
0.000 0.376 0.624
E53 Deficiency of other B group vitamins
0.000 0.380 0.620
E27.2 Addisonian crisis
0.000 0.381 0.619
E13.8 With unspecified complications
0.000 0.382 0.618
E13.7 With multiple complications
0.000 0.382 0.618
E13.6 With other specified complications
0.000 0.382 0.618
E13.5 With peripheral circulatory complications
0.000 0.382 0.618
E13.4 With neurological complications
0.000 0.382 0.618
E13.3 With ophthalmic complications
0.000 0.382 0.618
E13.2 With renal complications
0.000 0.382 0.618
E13.1 With ketoacidosis
0.000 0.382 0.618
E13.0 With coma
0.000 0.382 0.618
E25 Adrenogenital disorders
0.000 0.389 0.611
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.609 0.391 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.391 0.608
E55.9 Vitamin D deficiency, unspecified
0.000 0.392 0.608
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.597 0.403 0.000
T36 Poisoning by systemic antibiotics
0.589 0.411 0.000
T42.0 Hydantoin derivatives
0.582 0.418 0.000
E26 Hyperaldosteronism
0.000 0.420 0.580
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.579 0.421 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.578 0.422 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.577 0.423 0.000
E34 Other endocrine disorders
0.000 0.430 0.570
E20.8 Other hypoparathyroidism
0.000 0.431 0.569
E20.1 Pseudohypoparathyroidism
0.000 0.431 0.569
E20.0 Idiopathic hypoparathyroidism
0.000 0.431 0.569
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.431 0.569
E63 Other nutritional deficiencies
0.000 0.431 0.569
E56 Other vitamin deficiencies
0.000 0.431 0.569
E50 Vitamin A deficiency
0.000 0.431 0.569
E60 Dietary zinc deficiency
0.000 0.431 0.569
E59 Dietary selenium deficiency
0.000 0.431 0.569
E58 Dietary calcium deficiency
0.000 0.431 0.569
E54 Ascorbic acid deficiency
0.000 0.431 0.569
E52 Niacin deficiency [pellagra]
0.000 0.431 0.569
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.569 0.431 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.569 0.431 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.569 0.431 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.569 0.431 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.568 0.432 0.000
T43.9 Psychotropic drug, unspecified
0.563 0.437 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.563 0.437 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.563 0.437 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.562 0.438 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.562 0.438 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.562 0.438 0.000
T42.3 Barbiturates
0.562 0.438 0.000
T42.2 Succinimides and oxazolidinediones
0.562 0.438 0.000
T43.6 Psychostimulants with abuse potential
0.561 0.439 0.000
E14.3 With ophthalmic complications
0.000 0.441 0.559
E51 Thiamine deficiency
0.000 0.448 0.552
E22 Hyperfunction of pituitary gland
0.000 0.450 0.549
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.547 0.453 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.454 0.546
T50.9 Other and unspecified drugs, medicaments and biological substances
0.542 0.458 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.538 0.461 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.537 0.463 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.467 0.533
E29.8 Other testicular dysfunction
0.000 0.467 0.533
E29.0 Testicular hyperfunction
0.000 0.467 0.533
T45.9 Primarily systemic and haematological agent, unspecified
0.521 0.479 0.000
T45.8 Other primarily systemic and haematological agents
0.521 0.479 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.521 0.479 0.000
T45.6 Fibrinolysis-affecting drugs
0.521 0.479 0.000
T45.4 Iron and its compounds
0.521 0.479 0.000
T45.3 Enzymes, not elsewhere classified
0.521 0.479 0.000
T45.2 Vitamins, not elsewhere classified
0.521 0.479 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.480 0.520
E07 Other disorders of thyroid
0.000 0.483 0.517
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
T39.4 Antirheumatics, not elsewhere classified
0.507 0.493 0.000
T39.2 Pyrazolone derivatives
0.507 0.493 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.505 0.495 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.505 0.495 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.505 0.495 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.505 0.495 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.505 0.495 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.505 0.495 0.000
T44.0 Anticholinesterase agents
0.505 0.495 0.000
T46.1 Calcium-channel blockers
0.500 0.500 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.501 0.499
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.502 0.498
E45 Retarded development following protein-energy malnutrition
0.000 0.502 0.498
E43 Unspecified severe protein-energy malnutrition
0.000 0.502 0.498
E42 Marasmic kwashiorkor
0.000 0.502 0.498
E41 Nutritional marasmus
0.000 0.502 0.498
E40 Kwashiorkor
0.000 0.502 0.498
E03.5 Myxoedema coma
0.000 0.505 0.495
E03.4 Atrophy of thyroid (acquired)
0.000 0.505 0.495
E03.3 Postinfectious hypothyroidism
0.000 0.505 0.495
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.505 0.495
E53.8 Deficiency of other specified B group vitamins
0.000 0.506 0.494
E55.0 Rickets, active
0.000 0.508 0.491
T46.5 Other antihypertensive drugs, not elsewhere classified
0.491 0.509 0.000
T40.6 Other and unspecified narcotics
0.486 0.514 0.000
T50.8 Diagnostic agents
0.482 0.518 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.520 0.480
E24.2 Drug-induced Cushing's syndrome
0.000 0.520 0.480
E28.2 Polycystic ovarian syndrome
0.000 0.521 0.479
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.479 0.521 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.479 0.521 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.478 0.522 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.523 0.477
T45.5 Anticoagulants
0.468 0.532 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.468 0.532 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.534 0.466
E30.8 Other disorders of puberty
0.000 0.534 0.466
E30.1 Precocious puberty
0.000 0.534 0.466
E30.0 Delayed puberty
0.000 0.534 0.466
E31.9 Polyglandular dysfunction, unspecified
0.000 0.534 0.466
E31.8 Other polyglandular dysfunction
0.000 0.534 0.466
E31.1 Polyglandular hyperfunction
0.000 0.534 0.466
E31.0 Autoimmune polyglandular failure
0.000 0.534 0.466
E32.9 Disease of thymus, unspecified
0.000 0.534 0.466
E32.8 Other diseases of thymus
0.000 0.534 0.466
E32.1 Abscess of thymus
0.000 0.534 0.466
E32.0 Persistent hyperplasia of thymus
0.000 0.534 0.466
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.534 0.466
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.534 0.466
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.534 0.466
T50.7 Analeptics and opioid receptor antagonists
0.466 0.534 0.000
T50.5 Appetite depressants
0.466 0.534 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.466 0.534 0.000
T50.1 Loop [high-ceiling] diuretics
0.466 0.534 0.000
T50.0 Mineralocorticoids and their antagonists
0.466 0.534 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.537 0.462
E28.8 Other ovarian dysfunction
0.000 0.537 0.462
E28.1 Androgen excess
0.000 0.537 0.462
E28.0 Oestrogen excess
0.000 0.537 0.462
E24.8 Other Cushing's syndrome
0.000 0.540 0.460
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.540 0.460
E24.3 Ectopic ACTH syndrome
0.000 0.540 0.460
E24.1 Nelson's syndrome
0.000 0.540 0.460
E06.5 Other chronic thyroiditis
0.000 0.541 0.458
E06.4 Drug-induced thyroiditis
0.000 0.541 0.458
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.541 0.458
E06.1 Subacute thyroiditis
0.000 0.541 0.458
E06.0 Acute thyroiditis
0.000 0.541 0.458
E14.1 With ketoacidosis
0.000 0.546 0.454
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.453 0.547 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.453 0.547 0.000
T46.7 Peripheral vasodilators
0.453 0.547 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.453 0.547 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.453 0.547 0.000
T40.1 Heroin
0.453 0.547 0.000
T39.1 4-Aminophenol derivatives
0.452 0.548 0.000
E14.7 With multiple complications
0.000 0.551 0.449
E14.6 With other specified complications
0.000 0.551 0.449
E14.2 Withrenal complications
0.000 0.551 0.449
E14.0 With coma
0.000 0.551 0.449
E06.3 Autoimmune thyroiditis
0.000 0.552 0.448
T40.5 Cocaine
0.447 0.553 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.554 0.446
E34.0 Carcinoid syndrome
0.000 0.554 0.446
E53.1 Pyridoxine deficiency
0.000 0.555 0.444
E53.0 Riboflavin deficiency
0.000 0.555 0.444
E14.8 With unspecified complications
0.000 0.556 0.444
T36.0 Penicillins
0.442 0.558 0.000
T50.4 Drugs affecting uric acid metabolism
0.442 0.558 0.000
E28.3 Primary ovarian failure
0.000 0.562 0.438
E25.9 Adrenogenital disorder, unspecified
0.000 0.562 0.438
E25.8 Other adrenogenital disorders
0.000 0.562 0.438
T38.1 Thyroid hormones and substitutes
0.437 0.563 0.000
E61 Deficiency of other nutrient elements
0.000 0.565 0.435
E14.5 With peripheral circulatory complications
0.000 0.568 0.432
E22.1 Hyperprolactinaemia
0.000 0.572 0.428
E14.4 With neurological complications
0.000 0.575 0.425
T47.1 Other antacids and anti-gastric-secretion drugs
0.424 0.576 0.000
T36.9 Systemic antibiotic, unspecified
0.422 0.578 0.000
T36.8 Other systemic antibiotics
0.422 0.578 0.000
T36.7 Antifungal antibiotics, systemically used
0.422 0.578 0.000
T36.6 Rifamycins
0.422 0.578 0.000
T36.5 Aminoglycosides
0.422 0.578 0.000
T36.4 Tetracyclines
0.422 0.578 0.000
T36.3 Macrolides
0.422 0.578 0.000
T36.2 Chloramphenicol group
0.422 0.578 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.422 0.578 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.584 0.416
E26.8 Other hyperaldosteronism
0.000 0.584 0.416
E26.1 Secondary hyperaldosteronism
0.000 0.584 0.416
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.415 0.585 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.415 0.585 0.000
T47.7 Emetics
0.415 0.585 0.000
T47.6 Antidiarrhoeal drugs
0.415 0.585 0.000
T47.5 Digestants
0.415 0.585 0.000
T47.4 Other laxatives
0.415 0.585 0.000
T47.3 Saline and osmotic laxatives
0.415 0.585 0.000
T47.2 Stimulant laxatives
0.415 0.585 0.000
T47.0 Histamine H(2)-receptor antagonists
0.415 0.585 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.588 0.412
E65-E68 Obesity and other hyperalimentation
0.000 0.589 0.410
E34.5 Androgen resistance syndrome
0.000 0.591 0.408
E34.4 Constitutional tall stature
0.000 0.591 0.408
E34.3 Short stature, not elsewhere classified
0.000 0.591 0.408
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.591 0.408
E34.1 Other hypersecretion of intestinal hormones
0.000 0.591 0.408
E50.9 Vitamin A deficiency, unspecified
0.000 0.592 0.408
E50.8 Other manifestations of vitamin A deficiency
0.000 0.592 0.408
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.592 0.408
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.592 0.408
E50.5 Vitamin A deficiency with night blindness
0.000 0.592 0.408
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.592 0.408
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.592 0.408
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.592 0.408
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.592 0.408
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.592 0.408
E56.9 Vitamin deficiency, unspecified
0.000 0.592 0.408
E56.8 Deficiency of other vitamins
0.000 0.592 0.408
E56.1 Deficiency of vitamin K
0.000 0.592 0.408
E56.0 Deficiency of vitamin E
0.000 0.592 0.408
E63.9 Nutritional deficiency, unspecified
0.000 0.592 0.408
E63.8 Other specified nutritional deficiencies
0.000 0.592 0.408
E63.1 Imbalance of constituents of food intake
0.000 0.592 0.408
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.592 0.408
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.592 0.408
E64.8 Sequelae of other nutritional deficiencies
0.000 0.592 0.408
E64.3 Sequelae of rickets
0.000 0.592 0.408
E64.2 Sequelae of vitamin C deficiency
0.000 0.592 0.408
E64.1 Sequelae of vitamin A deficiency
0.000 0.592 0.408
E64.0 Sequelae of protein-energy malnutrition
0.000 0.592 0.408
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.408 0.592 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.408 0.592 0.000
T37.5 Antiviral drugs
0.408 0.592 0.000
T37.4 Anthelminthics
0.408 0.592 0.000
T37.3 Other antiprotozoal drugs
0.408 0.592 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.408 0.592 0.000
T37.1 Antimycobacterial drugs
0.408 0.592 0.000
T37.0 Sulphonamides
0.408 0.592 0.000
T41.5 Therapeutic gases
0.408 0.592 0.000
T41.4 Anaesthetic, unspecified
0.408 0.592 0.000
T41.3 Local anaesthetics
0.408 0.592 0.000
T41.2 Other and unspecified general anaesthetics
0.408 0.592 0.000
T41.1 Intravenous anaesthetics
0.408 0.592 0.000
T41.0 Inhaled anaesthetics
0.408 0.592 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.408 0.592 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.408 0.592 0.000
T48.5 Anti-common-cold drugs
0.408 0.592 0.000
T48.4 Expectorants
0.408 0.592 0.000
T48.3 Antitussives
0.408 0.592 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.408 0.592 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.408 0.592 0.000
T48.0 Oxytocic drugs
0.408 0.592 0.000
T49.9 Topical agent, unspecified
0.408 0.592 0.000
T49.8 Other topical agents
0.408 0.592 0.000
T49.7 Dental drugs, topically applied
0.408 0.592 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.408 0.592 0.000
T49.5 Ophthalmological drugs and preparations
0.408 0.592 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.408 0.592 0.000
T49.3 Emollients, demulcents and protectants
0.408 0.592 0.000
T49.2 Local astringents and local detergents
0.408 0.592 0.000
T49.1 Antipruritics
0.408 0.592 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.408 0.592 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.407 0.592 0.000
T40.8 Lysergide [LSD]
0.407 0.592 0.000
T40.7 Cannabis (derivatives)
0.407 0.592 0.000
T40.3 Methadone
0.407 0.592 0.000
T40.0 Opium
0.407 0.592 0.000
T38.9 Other and unspecified hormone antagonists
0.403 0.597 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.403 0.597 0.000
T38.7 Androgens and anabolic congeners
0.403 0.597 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.403 0.597 0.000
T38.5 Other oestrogens and progestogens
0.403 0.597 0.000
T38.4 Oral contraceptives
0.403 0.597 0.000
T38.2 Antithyroid drugs
0.403 0.597 0.000
T38.0 Glucocorticoids and synthetic analogues
0.403 0.597 0.000
E06.9 Thyroiditis, unspecified
0.000 0.601 0.399
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.601 0.398
E51.9 Thiamine deficiency, unspecified
0.000 0.604 0.395
E51.8 Other manifestations of thiamine deficiency
0.000 0.604 0.395
E51.1 Beriberi
0.000 0.604 0.395
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.395 0.604 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.606 0.394
E22.8 Other hyperfunction of pituitary gland
0.000 0.606 0.394
E03.8 Other specified hypothyroidism
0.000 0.617 0.383
E51.2 Wernicke's encephalopathy
0.000 0.622 0.378
E24.9 Cushing's syndrome, unspecified
0.000 0.629 0.371
E07.1 Dyshormogenetic goitre
0.000 0.629 0.371
E07.0 Hypersecretion of calcitonin
0.000 0.629 0.371
T39.0 Salicylates
0.369 0.631 0.000
E34.8 Other specified endocrine disorders
0.000 0.636 0.364
T46.4 Angiotensin-converting-enzyme inhibitors
0.363 0.637 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.642 0.358
E44.1 Mild protein-energy malnutrition
0.000 0.642 0.357
E44.0 Moderate protein-energy malnutrition
0.000 0.642 0.357
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.352 0.648 0.000
E26.0 Primary hyperaldosteronism
0.000 0.654 0.346
T43.0 Tricyclic and tetracyclic antidepressants
0.344 0.656 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.677 0.323
E07.8 Other specified disorders of thyroid
0.000 0.687 0.313
E61.9 Deficiency of nutrient element, unspecified
0.000 0.688 0.312
E61.8 Deficiency of other specified nutrient elements
0.000 0.688 0.312
E61.7 Deficiency of multiple nutrient elements
0.000 0.688 0.312
E61.6 Vanadium deficiency
0.000 0.688 0.312
E61.5 Molybdenum deficiency
0.000 0.688 0.312
E61.4 Chromium deficiency
0.000 0.688 0.312
E61.3 Manganese deficiency
0.000 0.688 0.312
E61.0 Copper deficiency
0.000 0.688 0.312
E67 Other hyperalimentation
0.000 0.705 0.294
E68 Sequelae of hyperalimentation
0.000 0.705 0.294
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.716 0.284
E65 Localised adiposity
0.000 0.716 0.283
E61.2 Magnesium deficiency
0.000 0.722 0.278
T40.2 Other opioids
0.276 0.724 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.728 0.272
T42.4 Benzodiazepines
0.253 0.746 0.000
T40.4 Other synthetic narcotics
0.247 0.753 0.000
E04 Other non-toxic goitre
0.000 0.760 0.240
E61.1 Iron deficiency
0.000 0.766 0.233
L40-L45 Papulosquamous disorders
0.228 0.771 0.000
E67.8 Other specified hyperalimentation
0.000 0.789 0.211
E67.3 Hypervitaminosis D
0.000 0.789 0.211
E67.2 Megavitamin-B6 syndrome
0.000 0.789 0.211
E67.1 Hypercarotenaemia
0.000 0.789 0.211
E67.0 Hypervitaminosis A
0.000 0.789 0.211
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.796 0.204
K90 Intestinal malabsorption
0.000 0.825 0.175
E04.8 Other specified non-toxic goitre
0.000 0.828 0.172
E04.0 Non-toxic diffuse goitre
0.000 0.828 0.172
L44 Other papulosquamous disorders
0.164 0.836 0.000
L41 Parapsoriasis
0.164 0.836 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.164 0.836 0.000
E23 Hypofunction and other disorders of pituitary gland
0.002 0.847 0.150
E21.2 Other hyperparathyroidism
0.000 0.854 0.146
L42 Pityriasis rosea
0.143 0.856 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.863 0.137
M06.9 Rheumatoid arthritis, unspecified
0.000 0.865 0.135
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.871 0.129
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.872 0.128
E21.4 Other specified disorders of parathyroid gland
0.000 0.873 0.127
K90.3 Pancreatic steatorrhoea
0.000 0.874 0.125
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.874 0.125
K90.1 Tropical sprue
0.000 0.874 0.125
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.877 0.123
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.879 0.121
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.881 0.119
L41.9 Parapsoriasis, unspecified
0.118 0.882 0.000
L41.8 Other parapsoriasis
0.118 0.882 0.000
L41.5 Retiform parapsoriasis
0.118 0.882 0.000
L41.4 Large plaque parapsoriasis
0.118 0.882 0.000
L41.3 Small plaque parapsoriasis
0.118 0.882 0.000
L41.2 Lymphomatoid papulosis
0.118 0.882 0.000
L41.1 Pityriasis lichenoides chronica
0.118 0.882 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.118 0.882 0.000
L44.9 Papulosquamous disorder, unspecified
0.118 0.882 0.000
L44.8 Other specified papulosquamous disorders
0.118 0.882 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.118 0.882 0.000
L44.3 Lichen ruber moniliformis
0.118 0.882 0.000
L44.2 Lichen striatus
0.118 0.882 0.000
L44.1 Lichen nitidus
0.118 0.882 0.000
L44.0 Pityriasis rubra pilaris
0.118 0.882 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.883 0.117
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.884 0.116
K90.8 Other intestinal malabsorption
0.000 0.884 0.116
E21.3 Hyperparathyroidism, unspecified
0.000 0.885 0.115
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.887 0.113
L43 Lichen planus
0.109 0.890 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.002 0.890 0.108
E23.1 Drug-induced hypopituitarism
0.002 0.890 0.108
E04.1 Non-toxic single thyroid nodule
0.000 0.891 0.109
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.891 0.109
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.893 0.107
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.898 0.102
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.910 0.090
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.911 0.089
E04.9 Non-toxic goitre, unspecified
0.000 0.914 0.086
L43.8 Other lichen planus
0.082 0.917 0.001
E23.6 Other disorders of pituitary gland
0.002 0.919 0.079
L43.3 Subacute (active) lichen planus
0.078 0.921 0.001
L43.2 Lichenoid drug reaction
0.078 0.921 0.001
L43.1 Bullous lichen planus
0.078 0.921 0.001
L43.0 Hypertrophic lichen planus
0.078 0.921 0.001
E14.9 Without complications
0.000 0.924 0.076
E23.7 Disorder of pituitary gland, unspecified
0.002 0.924 0.073
M06 Other rheumatoid arthritis
0.001 0.925 0.074
E23.0 Hypopituitarism
0.001 0.926 0.072
K90.9 Intestinal malabsorption, unspecified
0.000 0.928 0.072
M06.4 Inflammatory polyarthropathy
0.001 0.933 0.066
M07.30 Other psoriatic arthropathies (Multiple sites)
0.065 0.935 0.000
M07.3 Other psoriatic arthropathies
0.063 0.937 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.058 0.942 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.943 0.057
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.943 0.056
E23.2 Diabetes insipidus
0.003 0.945 0.053
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.054 0.946 0.000
M06.8 Other specified rheumatoid arthritis
0.001 0.946 0.053
M06.2 Rheumatoid bursitis
0.001 0.946 0.053
M06.1 Adult-onset Still's disease
0.001 0.946 0.053
M07.36 Other psoriatic arthropathies (Lower leg)
0.049 0.950 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.049 0.950 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.049 0.951 0.000
M06.3 Rheumatoid nodule
0.001 0.951 0.048
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.952 0.048
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.952 0.048
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.952 0.048
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.952 0.048
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.952 0.048

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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