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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2534674
log Bayes Factor = 90.8041
Chromosome 6   position 31,465,103  (GRCh37) Explore rs2534674 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M45 Ankylosing spondylitis
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
E14.9 Without complications
0.000 0.005 0.995
M06.9 Rheumatoid arthritis, unspecified
0.000 0.007 0.993
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E10.4 With neurological complications
0.000 0.011 0.989
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.015 0.985
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.020 0.980
E16 Other disorders of pancreatic internal secretion
0.000 0.034 0.966
L40 Psoriasis
0.965 0.035 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.040 0.960
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.041 0.959
L40.0 Psoriasis vulgaris
0.939 0.061 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.066 0.934
M06 Other rheumatoid arthritis
0.000 0.075 0.925
M35 Other systemic involvement of connective tissue
0.000 0.083 0.917
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.085 0.915
M34 Systemic sclerosis
0.000 0.088 0.912
M35.0 Sicca syndrome [Sjogren]
0.000 0.090 0.910
M20-M25 Other joint disorders
0.000 0.090 0.910
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.091 0.909
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.092 0.908
E06 Thyroiditis
0.000 0.092 0.908
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.094 0.906
E10.0 With coma
0.000 0.100 0.900
M45-M49 Spondylopathies
0.000 0.102 0.898
M34.1 CR(E)ST syndrome
0.000 0.106 0.894
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.109 0.891
E10.5 With peripheral circulatory complications
0.000 0.113 0.887
M05-M14 Inflammatory polyarthropathies
0.000 0.114 0.886
L40.5 Arthropathic psoriasis
0.883 0.117 0.000
M34.9 Systemic sclerosis, unspecified
0.000 0.124 0.876
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.125 0.875
M35.1 Other overlap syndromes
0.000 0.128 0.872
H36.0 Diabetic retinopathy
0.000 0.149 0.851
E14.6 With other specified complications
0.000 0.156 0.844
E06.3 Autoimmune thyroiditis
0.000 0.164 0.836
E10.2 With renal complications
0.000 0.164 0.836
M35.2 Behcet's disease
0.000 0.185 0.815
M23.3 Other meniscus derangements
0.000 0.187 0.813
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.192 0.808
M34.8 Other forms of systemic sclerosis
0.000 0.192 0.808
M23 Internal derangement of knee
0.000 0.195 0.805
E14.8 With unspecified complications
0.000 0.200 0.800
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.202 0.798
M22 Disorders of patella
0.000 0.213 0.787
M70-M79 Other soft tissue disorders
0.000 0.232 0.768
J45.9 Asthma, unspecified
0.000 0.234 0.766
M35.3 Polymyalgia rheumatica
0.000 0.235 0.765
E10.7 With multiple complications
0.000 0.252 0.748
M75 Shoulder lesions
0.000 0.260 0.740
H36 Retinal disorders in diseases classified elsewhere
0.000 0.261 0.739
E10.8 With unspecified complications
0.000 0.263 0.737
M75.0 Adhesive capsulitis of shoulder
0.000 0.263 0.737
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.266 0.734
E14.1 With ketoacidosis
0.000 0.270 0.730
M49 Spondylopathies in diseases classified elsewhere
0.000 0.273 0.727
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.274 0.726
L40.1 Generalised pustular psoriasis
0.726 0.274 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.275 0.725
E14.5 With peripheral circulatory complications
0.000 0.278 0.722
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.000 0.280 0.720
E13 Other specified diabetes mellitus
0.000 0.282 0.718
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
M32 Systemic lupus erythematosus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.284 0.716
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.284 0.716
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.284 0.716
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.284 0.716
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.284 0.716
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.284 0.716
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.284 0.716
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.287 0.712
E14.2 Withrenal complications
0.000 0.288 0.712
M06.0 Seronegative rheumatoid arthritis
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.000 0.297 0.703
M22.8 Other disorders of patella
0.000 0.303 0.697
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.307 0.693
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.307 0.693
E16.4 Abnormal secretion of gastrin
0.000 0.307 0.693
E16.3 Increased secretion of glucagon
0.000 0.307 0.693
L40.4 Guttate psoriasis
0.692 0.308 0.000
L40.2 Acrodermatitis continua
0.692 0.308 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.310 0.690
E14.4 With neurological complications
0.000 0.313 0.687
M34.0 Progressive systemic sclerosis
0.000 0.314 0.686
E83.1 Disorders of iron metabolism
0.685 0.315 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.320 0.680
M35.8 Other specified systemic involvement of connective tissue
0.000 0.326 0.674
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.326 0.674
M80-M85 Disorders of bone density and structure
0.000 0.326 0.674
E06.9 Thyroiditis, unspecified
0.000 0.329 0.671
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.330 0.669
M06.8 Other specified rheumatoid arthritis
0.000 0.331 0.669
M06.3 Rheumatoid nodule
0.000 0.331 0.669
I20-I25 Ischaemic heart diseases
0.000 0.333 0.667
I22 Subsequent myocardial infarction
0.000 0.336 0.664
M70.4 Prepatellar bursitis
0.000 0.336 0.664
M06.2 Rheumatoid bursitis
0.000 0.337 0.663
M06.1 Adult-onset Still's disease
0.000 0.337 0.663
K90 Intestinal malabsorption
0.000 0.341 0.659
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.342 0.658
H30-H36 Disorders of choroid and retina
0.000 0.342 0.658
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.342 0.658
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.342 0.658
M35.5 Multifocal fibrosclerosis
0.000 0.342 0.658
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.342 0.658
M22.9 Disorder of patella, unspecified
0.000 0.343 0.657
M70.6 Trochanteric bursitis
0.000 0.343 0.657
E10.6 With other specified complications
0.000 0.343 0.657
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.346 0.654
L40.3 Pustulosis palmaris et plantaris
0.652 0.348 0.000
I20.9 Angina pectoris, unspecified
0.000 0.349 0.651
E06.5 Other chronic thyroiditis
0.000 0.349 0.651
E06.4 Drug-induced thyroiditis
0.000 0.349 0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.349 0.651
E06.1 Subacute thyroiditis
0.000 0.349 0.651
E06.0 Acute thyroiditis
0.000 0.349 0.651
I20 Angina pectoris
0.000 0.351 0.649
M80 Osteoporosis with pathological fracture
0.000 0.352 0.648
I25 Chronic ischaemic heart disease
0.000 0.353 0.647
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.353 0.647
I25.1 Atherosclerotic heart disease
0.000 0.355 0.645
H35 Other retinal disorders
0.000 0.356 0.644
I25.5 Ischaemic cardiomyopathy
0.000 0.364 0.636
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.364 0.636
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.365 0.635
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.000 0.367 0.633
E14.0 With coma
0.000 0.367 0.632
H35.8 Other specified retinal disorders
0.000 0.372 0.628
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.373 0.627
E11 Non-insulin-dependent diabetes mellitus
0.000 0.376 0.624
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.376 0.624
M22.3 Other derangements of patella
0.000 0.378 0.622
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.379 0.621
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.380 0.620
M08 Juvenile arthritis
0.000 0.380 0.620
M35.7 Hypermobility syndrome
0.000 0.384 0.616
M82 Osteoporosis in diseases classified elsewhere
0.000 0.387 0.613
E40-E46 Malnutrition
0.000 0.388 0.612
M22.0 Recurrent dislocation of patella
0.000 0.393 0.607
M75.4 Impingement syndrome of shoulder
0.000 0.394 0.606
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.394 0.606
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.398 0.602
L40.8 Other psoriasis
0.600 0.400 0.000
H35.4 Peripheral retinal degeneration
0.000 0.409 0.591
M00-M03 Infectious arthropathies
0.000 0.411 0.589
M75.5 Bursitis of shoulder
0.000 0.412 0.588
E16.1 Other hypoglycaemia
0.000 0.415 0.585
E11.9 Without complications
0.000 0.417 0.583
M23.37 Other meniscus derangements-Capsular lig
0.000 0.417 0.583
H35.5 Hereditary retinal dystrophy
0.000 0.418 0.582
E03.1 Congenital hypothyroidism without goitre
0.000 0.418 0.581
M70.2 Olecranon bursitis
0.000 0.421 0.579
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.423 0.577
I23 Certain current complications following acute myocardial infarction
0.000 0.423 0.577
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.426 0.574
E13.3 With ophthalmic complications
0.000 0.429 0.570
M82.1 Osteoporosis in endocrine disorders
0.000 0.430 0.570
M22.1 Recurrent subluxation of patella
0.000 0.436 0.564
M30 Polyarteritis nodosa and related conditions
0.000 0.437 0.562
M06.34 Rheumatoid nodule (Hand)
0.000 0.440 0.560
E11.0 With coma
0.000 0.442 0.558
H35.2 Other proliferative retinopathy
0.000 0.442 0.558
M23.4 Loose body in knee
0.000 0.448 0.552
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.448 0.552
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.449 0.551
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.452 0.548
K90.9 Intestinal malabsorption, unspecified
0.000 0.454 0.546
M12 Other specific arthropathies
0.000 0.462 0.538
I24 Other acute ischaemic heart diseases
0.000 0.463 0.537
M05 Seropositive rheumatoid arthritis
0.000 0.465 0.535
E65-E68 Obesity and other hyperalimentation
0.000 0.468 0.532
M75.8 Other shoulder lesions
0.000 0.469 0.531
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.470 0.530
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.470 0.530
H20.9 Iridocyclitis, unspecified
0.000 0.474 0.526
M33 Dermatopolymyositis
0.000 0.474 0.525
# Top node
0.000 0.477 0.523
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.478 0.522
M49.4 Neuropathic spondylopathy
0.000 0.478 0.522
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.478 0.522
M49.2 Enterobacterial spondylitis
0.000 0.478 0.522
M49.1 Brucella spondylitis
0.000 0.478 0.522
M49.0 Tuberculosis of spine
0.000 0.478 0.522
Chapter VII Diseases of the eye and adnexa
0.000 0.479 0.521
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.479 0.521
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.479 0.521
M70.1 Bursitis of hand
0.000 0.479 0.521
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.479 0.521
M10 Gout
0.000 0.479 0.521
H35.7 Separation of retinal layers
0.000 0.480 0.520
Chapter VIII Diseases of the ear and mastoid process
0.000 0.481 0.519
M32.8 Other forms of systemic lupus erythematosus
0.000 0.484 0.516
E13.8 With unspecified complications
0.000 0.485 0.515
E13.7 With multiple complications
0.000 0.485 0.515
E13.6 With other specified complications
0.000 0.485 0.515
E13.5 With peripheral circulatory complications
0.000 0.485 0.515
E13.4 With neurological complications
0.000 0.485 0.515
E13.2 With renal complications
0.000 0.485 0.515
E13.1 With ketoacidosis
0.000 0.485 0.515
E13.0 With coma
0.000 0.485 0.515
H20 Iridocyclitis
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.486 0.514
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.486 0.514
H65-H75 Diseases of middle ear and mastoid
0.000 0.486 0.514
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.486 0.514
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.000 0.487 0.513
I23.8 Other current complications following acute myocardial infarction
0.000 0.487 0.513
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.488 0.512
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.490 0.510
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.490 0.510
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.490 0.510
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.490 0.510
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.490 0.510
M75.2 Bicipital tendinitis
0.000 0.491 0.509
M06.4 Inflammatory polyarthropathy
0.000 0.493 0.507
M70.3 Other bursitis of elbow
0.000 0.494 0.506
M23.5 Chronic instability of knee
0.000 0.494 0.506
Chapter IX Diseases of the circulatory system
0.000 0.495 0.505
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.495 0.505
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.496 0.504
M25 Other joint disorders, not elsewhere classified
0.000 0.498 0.502
M76 Enthesopathies of lower limb, excluding foot
0.000 0.498 0.502
M23.6 Other spontaneous disruption of ligament(s) of knee
0.000 0.498 0.502
H73 Other disorders of tympanic membrane
0.000 0.499 0.501
E07 Other disorders of thyroid
0.000 0.502 0.498
M11 Other crystal arthropathies
0.000 0.504 0.496
M22.2 Patellofemoral disorders
0.000 0.506 0.494
M70.22 Olecranon bursitis-Upper arm
0.000 0.507 0.493
M23.0 Cystic meniscus
0.000 0.507 0.493
H73.8 Other specified disorders of tympanic membrane
0.000 0.511 0.489
M14 Arthropathies in other diseases classified elsewhere
0.000 0.511 0.488
K90.8 Other intestinal malabsorption
0.000 0.512 0.488
H60-H62 Diseases of external ear
0.000 0.513 0.487
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.514 0.486
E03.8 Other specified hypothyroidism
0.000 0.514 0.486
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.516 0.484
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.000 0.517 0.483
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.000 0.519 0.481
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.520 0.480
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.520 0.480
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.520 0.480
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.520 0.480
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.520 0.480
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.520 0.480
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.520 0.480
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.520 0.480
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.520 0.480
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.520 0.480
M06.38 Rheumatoid nodule (Other)
0.000 0.520 0.480
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.520 0.480
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.520 0.480
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.520 0.480
M25.4 Effusion of joint
0.000 0.520 0.480
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.521 0.478
M46 Other inflammatory spondylopathies
0.000 0.523 0.477
M70.49 Prepatellar bursitis-Site unspec
0.000 0.524 0.476
M70.48 Prepatellar bursitis-Other
0.000 0.524 0.476
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.524 0.476
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.524 0.476
M70.44 Prepatellar bursitis-Hand
0.000 0.524 0.476
M70.43 Prepatellar bursitis-Forearm
0.000 0.524 0.476
M70.42 Prepatellar bursitis-Upper arm
0.000 0.524 0.476
M70.41 Prepatellar bursitis-Shldr region
0.000 0.524 0.476
M70.40 Prepatellar bursitis-Mult sites
0.000 0.524 0.476
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.524 0.475
M06.18 Adult-onset Still's disease (Other)
0.000 0.524 0.475
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.524 0.475
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.524 0.475
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.524 0.475
M06.14 Adult-onset Still's disease (Hand)
0.000 0.524 0.475
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.524 0.475
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.524 0.475
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.524 0.475
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.524 0.475
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.524 0.475
M06.28 Rheumatoid bursitis (Other)
0.000 0.524 0.475
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.524 0.475
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.524 0.475
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.524 0.475
M06.24 Rheumatoid bursitis (Hand)
0.000 0.524 0.475
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.524 0.475
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.524 0.475
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.524 0.475
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.524 0.475
H66.3 Other chronic suppurative otitis media
0.000 0.525 0.475
H66 Suppurative and unspecified otitis media
0.000 0.527 0.473
K90.3 Pancreatic steatorrhoea
0.000 0.527 0.472
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.527 0.472
K90.1 Tropical sprue
0.000 0.527 0.472
I20.1 Angina pectoris with documented spasm
0.000 0.528 0.472
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.528 0.472
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.528 0.472
M70.68 Trochanteric bursitis-Other
0.000 0.529 0.471
M70.67 Trochanteric bursitis-Ankle/Foot
0.000 0.529 0.471
M70.66 Trochanteric bursitis-Lower Leg
0.000 0.529 0.471
M70.64 Trochanteric bursitis-Hand
0.000 0.529 0.471
M70.63 Trochanteric bursitis-Forearm
0.000 0.529 0.471
M70.62 Trochanteric bursitis-Upper arm
0.000 0.529 0.471
M70.61 Trochanteric bursitis-Shldr region
0.000 0.529 0.471
M70.60 Trochanteric bursitis-Mult sites
0.000 0.529 0.471
I10-I15 Hypertensive diseases
0.000 0.531 0.469
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.531 0.469
M25.3 Other instability of joint
0.000 0.533 0.467
M83 Adult osteomalacia
0.000 0.535 0.465
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.535 0.465
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.535 0.465
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.535 0.465
M70.7 Other bursitis of hip
0.000 0.535 0.464
I25.6 Silent myocardial ischaemia
0.000 0.536 0.464
H35.1 Retinopathy of prematurity
0.000 0.538 0.462
H74 Other disorders of middle ear and mastoid
0.000 0.540 0.460
H71 Cholesteatoma of middle ear
0.000 0.541 0.459
E11.1 With ketoacidosis
0.000 0.543 0.457
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.000 0.544 0.456
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.000 0.544 0.456
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.544 0.456
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.000 0.544 0.456
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.000 0.544 0.456
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.000 0.544 0.456
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.000 0.544 0.456
M23.9 Internal derangement of knee, unspecified
0.000 0.544 0.455
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.544 0.455
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.544 0.455
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.544 0.455
M09.0 Juvenile arthritis in psoriasis
0.000 0.544 0.455
M23.43 Loose body in knee-Med lig/oth men
0.000 0.546 0.454
E11.7 With multiple complications
0.000 0.552 0.448
M75.3 Calcific tendinitis of shoulder
0.000 0.552 0.448
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.554 0.446
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.554 0.446
H20.0 Acute and subacute iridocyclitis
0.000 0.554 0.445
M08.9 Juvenile arthritis, unspecified
0.000 0.555 0.444
M08.8 Other juvenile arthritis
0.000 0.555 0.444
M08.4 Pauciarticular juvenile arthritis
0.000 0.555 0.444
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.555 0.444
M08.2 Juvenile arthritis with systemic onset
0.000 0.555 0.444
M08.1 Juvenile ankylosing spondylitis
0.000 0.555 0.444
M25.36 Other instability of joint (Lower leg)
0.000 0.556 0.444
M23.1 Discoid meniscus (congenital)
0.001 0.557 0.442
I12 Hypertensive renal disease
0.000 0.558 0.442
E13.9 Without complications
0.000 0.559 0.441
M60-M63 Disorders of muscles
0.000 0.560 0.440
M82.8 Osteoporosis in other diseases classified elsewhere
0.000 0.560 0.440
M82.0 Osteoporosis in multiple myelomatosis
0.000 0.560 0.440
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.000 0.560 0.440
M30.0 Polyarteritis nodosa
0.000 0.560 0.439
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.561 0.439
E45 Retarded development following protein-energy malnutrition
0.000 0.561 0.439
E43 Unspecified severe protein-energy malnutrition
0.000 0.561 0.439
E42 Marasmic kwashiorkor
0.000 0.561 0.439
E41 Nutritional marasmus
0.000 0.561 0.439
E40 Kwashiorkor
0.000 0.561 0.439
H21 Other disorders of iris and ciliary body
0.000 0.562 0.438
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.000 0.566 0.434
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.566 0.434
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.000 0.566 0.434
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.000 0.566 0.434
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.000 0.566 0.434
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.000 0.566 0.434
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.566 0.434
I22.8 Subsequent myocardial infarction of other sites
0.000 0.568 0.432
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.568 0.432
M25.47 Effusion of joint (Ankle and foot)
0.000 0.568 0.432
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.568 0.432
M36.3 Arthropathy in other blood disorders
0.000 0.568 0.432
M36.2 Haemophilic arthropathy
0.000 0.568 0.432
M36.1 Arthropathy in neoplastic disease
0.000 0.568 0.432
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.568 0.432
I12.9 Hypertensive renal disease without renal failure
0.000 0.568 0.432
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.568 0.432
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.568 0.431
H60 Otitis externa
0.000 0.569 0.431
E05.8 Other thyrotoxicosis
0.001 0.570 0.429
M70.5 Other bursitis of knee
0.000 0.571 0.429
H30 Chorioretinal inflammation
0.000 0.571 0.429
M08.0 Juvenile rheumatoid arthritis
0.000 0.571 0.429
E11.3 With ophthalmic complications
0.000 0.572 0.428
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.572 0.428
M80.8 Other osteoporosis with pathological fracture
0.000 0.573 0.427
M06.33 Rheumatoid nodule (Forearm)
0.000 0.577 0.423
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.577 0.423
M25.40 Effusion of joint (Multiple sites)
0.000 0.577 0.423
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.577 0.422
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.577 0.422
M25.42 Effusion of joint (Upper arm)
0.000 0.578 0.422
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.000 0.581 0.419
M70.29 Olecranon bursitis-Site unspec
0.000 0.585 0.415
M70.28 Olecranon bursitis-Other
0.000 0.585 0.415
M70.27 Olecranon bursitis-Ankle/Foot
0.000 0.585 0.415
M70.26 Olecranon bursitis-Lower Leg
0.000 0.585 0.415
M70.25 Olecranon bursitis-Pelvic/Thigh
0.000 0.585 0.415
M70.24 Olecranon bursitis-Hand
0.000 0.585 0.415
M70.21 Olecranon bursitis-Shldr region
0.000 0.585 0.415
M70.20 Olecranon bursitis-Mult sites
0.000 0.585 0.415
H35.6 Retinal haemorrhage
0.000 0.585 0.415
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.586 0.414
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.586 0.414
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.586 0.414
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.586 0.414
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.586 0.414
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.586 0.414
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.586 0.414
H61 Other disorders of external ear
0.000 0.586 0.414
H15 Disorders of sclera
0.000 0.588 0.412
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.588 0.412
E65 Localised adiposity
0.000 0.589 0.411
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.590 0.410
M23.46 Loose body in knee-O/unsp lat men
0.000 0.591 0.409
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.000 0.591 0.408
M82.18 Osteoporosis in endocrine disorders (Other)
0.000 0.591 0.408
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.000 0.591 0.408
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.000 0.591 0.408
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.000 0.591 0.408
M82.14 Osteoporosis in endocrine disorders (Hand)
0.000 0.591 0.408
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.000 0.591 0.408
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.000 0.591 0.408
I25.4 Coronary artery aneurysm
0.000 0.592 0.407
M80.0 Postmenopausal osteoporosis with pathological fracture
0.000 0.593 0.407
M40-M43 Deforming dorsopathies
0.000 0.593 0.407
H31 Other disorders of choroid
0.000 0.595 0.405
M22.10 Recurrent subluxation of patella, unspecified knee
0.000 0.595 0.405
M23.41 Loose body in knee-Ant lig/hrn men
0.000 0.596 0.404
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.596 0.403
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.596 0.403
M30.2 Juvenile polyarteritis
0.000 0.596 0.403
M70.69 Trochanteric bursitis-Site unspec
0.000 0.597 0.403
M02 Reactive arthropathies
0.000 0.597 0.403
M25.34 Other instability of joint (Hand)
0.000 0.598 0.402
M13 Other arthritis
0.000 0.599 0.400
M79.9 Soft tissue disorder, unspecified
0.000 0.600 0.400
G35 Multiple sclerosis
0.400 0.600 0.000
M25.0 Haemarthrosis
0.000 0.601 0.399
I15 Secondary hypertension
0.000 0.603 0.397
M25.43 Effusion of joint (Forearm)
0.000 0.603 0.397
M05.8 Other seropositive rheumatoid arthritis
0.000 0.603 0.397
M00 Pyogenic arthritis
0.000 0.604 0.396
M23.47 Loose body in knee-Capsular lig
0.000 0.604 0.396
M23.45 Loose body in knee-Pst hrn lat men
0.000 0.604 0.396
M23.44 Loose body in knee-Lat lig/ant men
0.000 0.604 0.396
M23.42 Loose body in knee-Pst lig/hrn men
0.000 0.604 0.396
M23.40 Loose body in knee-Mult sites
0.000 0.604 0.396
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.000 0.604 0.396
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.000 0.604 0.396
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.000 0.604 0.396
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.000 0.604 0.396
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.604 0.396
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.000 0.604 0.396
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.000 0.604 0.396
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.000 0.604 0.396
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.000 0.604 0.396
H21.0 Hyphaema
0.000 0.604 0.396
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.000 0.605 0.395
M73.1 Syphilitic bursitis
0.000 0.605 0.395

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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