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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2648908
log Bayes Factor = 12.2754
Chromosome 8   position 129,127,594  (GRCh37) Explore rs2648908 on Ensembl!
Variant rs2648908 is part of Cluster X0041

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
H25-H28 Disorders of lens
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
I60-I69 Cerebrovascular diseases
0.993 0.007 0.000
H25 Senile cataract
0.993 0.007 0.000
C79 Secondary malignant neoplasm of other sites
0.993 0.007 0.000
H25.0 Senile incipient cataract
0.984 0.016 0.000
H43-H45 Disorders of vitreous body and globe
0.981 0.019 0.000
S60-S69 Injuries to the wrist and hand
0.981 0.019 0.000
Chapter V Mental and behavioural disorders
0.977 0.023 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
M06 Other rheumatoid arthritis
0.967 0.033 0.000
H43 Disorders of vitreous body
0.961 0.039 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.954 0.046 0.000
I67 Other cerebrovascular diseases
0.954 0.046 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.953 0.047 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.952 0.048 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.950 0.050 0.000
Chapter I Certain infectious and parasitic diseases
0.949 0.051 0.000
H25.8 Other senile cataract
0.949 0.051 0.000
M06.9 Rheumatoid arthritis, unspecified
0.948 0.052 0.000
C64-C68 Malignant neoplasms of urinary tract
0.939 0.061 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.934 0.066 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.932 0.068 0.000
H27 Other disorders of lens
0.931 0.069 0.000
F41 Other anxiety disorders
0.926 0.074 0.000
M45-M49 Spondylopathies
0.924 0.076 0.000
S64 Injury of nerves at wrist and hand level
0.923 0.077 0.000
I60 Subarachnoid haemorrhage
0.922 0.078 0.000
H43.3 Other vitreous opacities
0.920 0.080 0.000
M07 Psoriatic and enteropathic arthropathies
0.920 0.080 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.918 0.082 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.910 0.090 0.000
M10 Gout
0.908 0.092 0.000
F41.2 Mixed anxiety and depressive disorder
0.908 0.092 0.000
M21 Other acquired deformities of limbs
0.905 0.095 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.902 0.098 0.000
S62 Fracture at wrist and hand level
0.902 0.098 0.000
I20-I25 Ischaemic heart diseases
0.901 0.099 0.000
M25 Other joint disorders, not elsewhere classified
0.900 0.100 0.000
S10-S19 Injuries to the neck
0.892 0.108 0.000
I95 Hypotension
0.884 0.116 0.000
I67.1 Cerebral aneurysm, nonruptured
0.884 0.116 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.876 0.124 0.000
H53-H54 Visual disturbances and blindness
0.874 0.126 0.000
S00-S09 Injuries to the head
0.874 0.126 0.000
D00-D09 In situ neoplasms
0.873 0.127 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.872 0.128 0.000
H43.1 Vitreous haemorrhage
0.871 0.129 0.000
M86-M90 Other osteopathies
0.871 0.129 0.000
M47 Spondylosis
0.869 0.131 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.869 0.131 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.868 0.132 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.867 0.133 0.000
C15-C26 Malignant neoplasms of digestive organs
0.867 0.133 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.867 0.133 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.865 0.135 0.000
M07.3 Other psoriatic arthropathies
0.865 0.135 0.000
I61 Intracerebral haemorrhage
0.860 0.140 0.000
S02 Fracture of skull and facial bones
0.857 0.143 0.000
S64.4 Injury of digital nerve of other finger
0.850 0.150 0.000
B35-B49 Mycoses
0.850 0.150 0.000
T66-T78 Other and unspecified effects of external causes
0.846 0.154 0.000
M10.9 Gout, unspecified
0.845 0.155 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.845 0.155 0.000
M40-M43 Deforming dorsopathies
0.844 0.156 0.000
M47.8 Other spondylosis
0.844 0.156 0.000
H10-H13 Disorders of conjunctiva
0.843 0.157 0.000
E65-E68 Obesity and other hyperalimentation
0.841 0.159 0.000
S70-S79 Injuries to the hip and thigh
0.839 0.161 0.000
F40 Phobic anxiety disorders
0.837 0.163 0.000
M31 Other necrotising vasculopathies
0.833 0.167 0.000
C71 Malignant neoplasm of brain
0.833 0.167 0.000
S80-S89 Injuries to the knee and lower leg
0.831 0.169 0.000
I95.1 Orthostatic hypotension
0.830 0.170 0.000
S60 Superficial injury of wrist and hand
0.828 0.172 0.000
M70-M79 Other soft tissue disorders
0.826 0.174 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.826 0.174 0.000
C25 Malignant neoplasm of pancreas
0.825 0.175 0.000
E20-E35 Disorders of other endocrine glands
0.822 0.178 0.000
H27.1 Dislocation of lens
0.822 0.178 0.000
S62.6 Fracture of other finger
0.819 0.181 0.000
M24 Other specific joint derangements
0.813 0.187 0.000
M22 Disorders of patella
0.813 0.187 0.000
Chapter XXI Factors influencing health status and contact with health services
0.812 0.188 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.809 0.191 0.000
C67 Malignant neoplasm of bladder
0.806 0.194 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.803 0.197 0.000
H44 Disorders of globe
0.800 0.200 0.000
I69 Sequelae of cerebrovascular disease
0.799 0.201 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.798 0.202 0.000
D45 Polycythaemia vera
0.798 0.202 0.000
M21.3 Wrist or foot drop (acquired)
0.797 0.203 0.000
M11 Other crystal arthropathies
0.795 0.205 0.000
S20-S29 Injuries to the thorax
0.795 0.205 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.795 0.205 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.794 0.206 0.000
S02.2 Fracture of nasal bones
0.792 0.208 0.000
E66 Obesity
0.792 0.208 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.792 0.208 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.791 0.209 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.791 0.209 0.000
C15 Malignant neoplasm of oesophagus
0.785 0.215 0.000
I20 Angina pectoris
0.784 0.216 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.782 0.218 0.000
I95.2 Hypotension due to drugs
0.781 0.219 0.000
I67.2 Cerebral atherosclerosis
0.780 0.220 0.000
S02.4 Fracture of malar and maxillary bones
0.780 0.220 0.000
M60-M63 Disorders of muscles
0.780 0.220 0.000
M25.4 Effusion of joint
0.780 0.220 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
M21.1 Varus deformity, not elsewhere classified
0.777 0.223 0.000
S50-S59 Injuries to the elbow and forearm
0.777 0.223 0.000
S61 Open wound of wrist and hand
0.774 0.226 0.000
Z02 Examination and encounter for administrative purposes
0.774 0.226 0.000
F30-F39 Mood [affective] disorders
0.773 0.227 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.773 0.227 0.000
H27.0 Aphakia
0.773 0.227 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.771 0.229 0.000
M86 Osteomyelitis
0.771 0.229 0.000
M45 Ankylosing spondylitis
0.770 0.230 0.000
M10.99 Gout, unspecified (Site unspecified)
0.769 0.231 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.768 0.232 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.767 0.233 0.000
E66.9 Obesity, unspecified
0.767 0.233 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.766 0.234 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.765 0.235 0.000
I67.9 Cerebrovascular disease, unspecified
0.764 0.236 0.000
Chapter XX External causes of morbidity and mortality
0.763 0.237 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.761 0.239 0.000
I73 Other peripheral vascular diseases
0.761 0.239 0.000
Z02.8 Other examinations for administrative purposes
0.759 0.241 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.758 0.242 0.000
S68 Traumatic amputation of wrist and hand
0.757 0.243 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.756 0.243 0.000
C25.0 Head of pancreas
0.756 0.244 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.755 0.245 0.000
H53 Visual disturbances
0.755 0.245 0.000
F40.2 Specific (isolated) phobias
0.755 0.245 0.000
H50 Other strabismus
0.755 0.245 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.754 0.246 0.000
M50-M54 Other dorsopathies
0.753 0.247 0.000
M91-M94 Chondropathies
0.753 0.247 0.000
I25 Chronic ischaemic heart disease
0.752 0.248 0.000
D03 Melanoma in situ
0.752 0.248 0.000
I20.0 Unstable angina
0.751 0.249 0.000
F80-F89 Disorders of psychological development
0.750 0.249 0.000
A30-A49 Other bacterial diseases
0.750 0.250 0.000
I25.1 Atherosclerotic heart disease
0.749 0.251 0.000
D37.9 Digestive organ, unspecified
0.747 0.252 0.000
S02.20 Fracture of nasal bones (closed)
0.746 0.254 0.000
M05 Seropositive rheumatoid arthritis
0.745 0.255 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.745 0.255 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.744 0.256 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.743 0.257 0.000
C51-C58 Malignant neoplasms of female genital organs
0.742 0.258 0.000
B95-B98 Bacterial, viral and other infectious agents
0.742 0.258 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.741 0.259 0.000
H27.8 Other specified disorders of lens
0.740 0.260 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.740 0.260 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.740 0.260 0.000
I77 Other disorders of arteries and arterioles
0.739 0.261 0.000
Q50-Q56 Congenital malformations of genital organs
0.738 0.262 0.000
C79.6 Secondary malignant neoplasm of ovary
0.737 0.263 0.000
M47.82 Other spondylosis (Cervical region)
0.736 0.264 0.000
F99-F99 Unspecified mental disorder
0.736 0.264 0.000
T78 Adverse effects, not elsewhere classified
0.735 0.264 0.000
E70-E90 Metabolic disorders
0.735 0.265 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.735 0.265 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.734 0.266 0.000
Z13 Special screening examination for other diseases and disorders
0.733 0.267 0.000
S64.3 Injury of digital nerve of thumb
0.733 0.267 0.000
S69 Other and unspecified injuries of wrist and hand
0.733 0.267 0.000
C66 Malignant neoplasm of ureter
0.732 0.268 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.731 0.269 0.000
S62.60 Fracture of other finger (closed)
0.731 0.269 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.731 0.269 0.000
Z74 Problems related to care-provider dependency
0.731 0.269 0.000
M31.3 Wegener's granulomatosis
0.730 0.270 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.730 0.270 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.729 0.270 0.000
C32 Malignant neoplasm of larynx
0.729 0.271 0.000
S11 Open wound of neck
0.727 0.273 0.000
B65-B83 Helminthiases
0.727 0.273 0.000
C34 Malignant neoplasm of bronchus and lung
0.727 0.273 0.000
E40-E46 Malnutrition
0.726 0.273 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.726 0.274 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.725 0.275 0.000
C25.9 Pancreas, unspecified
0.725 0.275 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.725 0.275 0.000
B37 Candidiasis
0.724 0.276 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.724 0.276 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.276 0.000
I62 Other nontraumatic intracranial haemorrhage
0.722 0.278 0.000
S61.0 Open wound of finger(s) without damage to nail
0.720 0.280 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.720 0.280 0.000
S70 Superficial injury of hip and thigh
0.720 0.280 0.000
I73.9 Peripheral vascular disease, unspecified
0.720 0.280 0.000
D37.0 Lip, oral cavity and pharynx
0.719 0.281 0.000
Q60-Q64 Congenital malformations of the urinary system
0.718 0.282 0.000
C71.9 Brain, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.716 0.283 0.000
M47.86 Other spondylosis (Lumbar region)
0.716 0.284 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
H11 Other disorders of conjunctiva
0.713 0.287 0.000
S05 Injury of eye and orbit
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.712 0.288 0.000
H25.2 Senile cataract, morgagnian type
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
S10 Superficial injury of neck
0.711 0.289 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.710 0.290 0.000
Q00-Q07 Congenital malformations of the nervous system
0.710 0.290 0.000
I67.8 Other specified cerebrovascular diseases
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
Chapter VIII Diseases of the ear and mastoid process
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.708 0.292 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.707 0.293 0.000
I21 Acute myocardial infarction
0.706 0.294 0.000
D37.4 Colon
0.705 0.295 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.703 0.296 0.000
S65 Injury of blood vessels at wrist and hand level
0.703 0.296 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.703 0.297 0.000
F60-F69 Disorders of adult personality and behaviour
0.703 0.297 0.000
M41 Scoliosis
0.703 0.297 0.000
Q80-Q89 Other congenital malformations
0.702 0.298 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.700 0.300 0.000
T79-T79 Certain early complications of trauma
0.699 0.301 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.699 0.301 0.000
E29 Testicular dysfunction
0.699 0.301 0.000
S60.8 Other superficial injuries of wrist and hand
0.699 0.301 0.000
S12 Fracture of neck
0.698 0.302 0.000
Z74.0 Reduced mobility
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.303 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
C17 Malignant neoplasm of small intestine
0.696 0.304 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.695 0.305 0.000
D37.1 Stomach
0.695 0.305 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.694 0.306 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
D04 Carcinoma in situ of skin
0.693 0.306 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.307 0.000
M06.8 Other specified rheumatoid arthritis
0.693 0.307 0.000
M06.4 Inflammatory polyarthropathy
0.693 0.307 0.000
M06.3 Rheumatoid nodule
0.693 0.307 0.000
M06.2 Rheumatoid bursitis
0.693 0.307 0.000
M06.1 Adult-onset Still's disease
0.693 0.307 0.000
F42 Obsessive-compulsive disorder
0.692 0.307 0.000
S80 Superficial injury of lower leg
0.692 0.308 0.000
B91 Sequelae of poliomyelitis
0.690 0.310 0.000
C71.2 Temporal lobe
0.690 0.310 0.000
F31 Bipolar affective disorder
0.689 0.311 0.000
H43.9 Disorder of vitreous body, unspecified
0.689 0.311 0.000
H43.2 Crystalline deposits in vitreous body
0.689 0.311 0.000
H43.0 Vitreous prolapse
0.689 0.311 0.000
H54 Blindness and low vision
0.687 0.313 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.687 0.313 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.686 0.313 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.686 0.314 0.000
M21.4 Flat foot [pes planus] (acquired)
0.684 0.316 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.684 0.316 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.684 0.316 0.000
I67.5 Moyamoya disease
0.684 0.316 0.000
I67.4 Hypertensive encephalopathy
0.684 0.316 0.000
I67.3 Progressive vascular leukoencephalopathy
0.684 0.316 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.684 0.316 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.684 0.316 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.683 0.317 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.683 0.317 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.683 0.317 0.000
F48 Other neurotic disorders
0.682 0.317 0.000
F44 Dissociative [conversion] disorders
0.682 0.317 0.000
E27 Other disorders of adrenal gland
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.680 0.319 0.000
B50-B64 Protozoal diseases
0.680 0.319 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.680 0.319 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.680 0.319 0.000
A75-A79 Rickettsioses
0.680 0.319 0.000
A70-A74 Other diseases caused by chlamydiae
0.680 0.319 0.000
A65-A69 Other spirochaetal diseases
0.680 0.319 0.000
A20-A28 Certain zoonotic bacterial diseases
0.680 0.319 0.000
A15-A19 Tuberculosis
0.680 0.319 0.000
C15.9 Oesophagus, unspecified
0.680 0.320 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.680 0.320 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.680 0.320 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.680 0.320 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.680 0.320 0.000
H53.2 Diplopia
0.679 0.321 0.000
M90 Osteopathies in diseases classified elsewhere
0.679 0.321 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.679 0.321 0.000
S19 Other and unspecified injuries of neck
0.678 0.322 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.677 0.322 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.676 0.324 0.000
S02.5 Fracture of tooth
0.675 0.325 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.673 0.327 0.000
C65 Malignant neoplasm of renal pelvis
0.673 0.327 0.000
M25.0 Haemarthrosis
0.671 0.329 0.000
H44.2 Degenerative myopia
0.669 0.331 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.669 0.331 0.000
M22.4 Chondromalacia patellae
0.668 0.332 0.000
A00-A09 Intestinal infectious diseases
0.668 0.332 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.668 0.332 0.000
B49 Unspecified mycosis
0.668 0.332 0.000
H27.9 Disorder of lens, unspecified
0.667 0.332 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.667 0.333 0.000
C85.1 B-cell lymphoma, unspecified
0.666 0.334 0.000
S62.61 Fracture of other finger (open)
0.664 0.336 0.000
F41.8 Other specified anxiety disorders
0.664 0.336 0.000
F41.3 Other mixed anxiety disorders
0.664 0.336 0.000
H43.8 Other disorders of vitreous body
0.663 0.336 0.000
H53.8 Other visual disturbances
0.663 0.337 0.000
M25.47 Effusion of joint (Ankle and foot)
0.663 0.337 0.000
C71.1 Frontal lobe
0.663 0.337 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.663 0.337 0.000
C79.2 Secondary malignant neoplasm of skin
0.663 0.337 0.000
M49 Spondylopathies in diseases classified elsewhere
0.662 0.337 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.662 0.338 0.000
S64.8 Injury of other nerves at wrist and hand level
0.662 0.338 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.662 0.338 0.000
S64.1 Injury of median nerve at wrist and hand level
0.662 0.338 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.662 0.338 0.000
B44 Aspergillosis
0.662 0.338 0.000
M25.5 Pain in joint
0.662 0.338 0.000
I60.8 Other subarachnoid haemorrhage
0.661 0.339 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.661 0.339 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.661 0.339 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.661 0.339 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.661 0.339 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.661 0.339 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.661 0.339 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.661 0.339 0.000
M50 Cervical disk disorders
0.660 0.340 0.000
M86.9 Osteomyelitis, unspecified
0.660 0.340 0.000
M07.6 Other enteropathic arthropathies
0.659 0.341 0.000
M07.5 Arthropathy in ulcerative colitis
0.659 0.341 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.659 0.341 0.000
M07.2 Psoriatic spondylitis
0.659 0.341 0.000
M07.1 Arthritis mutilans
0.659 0.341 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.659 0.341 0.000
D46 Myelodysplastic syndromes
0.659 0.341 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.658 0.342 0.000
Q35-Q37 Cleft lip and cleft palate
0.658 0.342 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.658 0.342 0.000
I22 Subsequent myocardial infarction
0.657 0.343 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.657 0.343 0.000
I05-I09 Chronic rheumatic heart diseases
0.657 0.343 0.000
M75 Shoulder lesions
0.655 0.345 0.000
C21 Malignant neoplasm of anus and anal canal
0.655 0.345 0.000
M43 Other deforming dorsopathies
0.654 0.346 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.654 0.346 0.000
I78 Diseases of capillaries
0.654 0.346 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.654 0.346 0.000
D03.5 Melanoma in situ of trunk
0.653 0.347 0.000
A80-A89 Viral infections of the central nervous system
0.653 0.347 0.000
S62.5 Fracture of thumb
0.652 0.348 0.000
S40 Superficial injury of shoulder and upper arm
0.652 0.348 0.000
M11.2 Other chondrocalcinosis
0.652 0.348 0.000
M10.4 Other secondary gout
0.651 0.349 0.000
M10.3 Gout due to impairment of renal function
0.651 0.349 0.000
M10.2 Drug-induced gout
0.651 0.349 0.000
M10.1 Lead-induced gout
0.651 0.349 0.000
M10.0 Idiopathic gout
0.651 0.349 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.650 0.350 0.000
M25.7 Osteophyte
0.650 0.350 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.650 0.350 0.000
M77 Other enthesopathies
0.650 0.350 0.000
M21.9 Acquired deformity of limb, unspecified
0.649 0.351 0.000
M21.8 Other specified acquired deformities of limbs
0.649 0.351 0.000
M21.7 Unequal limb length (acquired)
0.649 0.351 0.000
M21.6 Other acquired deformities of ankle and foot
0.649 0.351 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.649 0.351 0.000
M21.2 Flexion deformity
0.649 0.351 0.000
M21.0 Valgus deformity, not elsewhere classified
0.649 0.351 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.649 0.351 0.000
F02 Dementia in other diseases classified elsewhere
0.649 0.351 0.000
H55-H59 Other disorders of eye and adnexa
0.648 0.352 0.000
M80-M85 Disorders of bone density and structure
0.647 0.353 0.000
H49 Paralytic strabismus
0.647 0.353 0.000
S02.0 Fracture of vault of skull
0.647 0.353 0.000
M06.0 Seronegative rheumatoid arthritis
0.647 0.353 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.647 0.353 0.000
C70 Malignant neoplasm of meninges
0.647 0.353 0.000
C69 Malignant neoplasm of eye and adnexa
0.647 0.353 0.000
S62.7 Multiple fractures of fingers
0.647 0.353 0.000
S62.4 Multiple fractures of metacarpal bones
0.647 0.353 0.000
S62.1 Fracture of other carpal bone(s)
0.647 0.353 0.000
I99 Other and unspecified disorders of circulatory system
0.647 0.353 0.000
E86 Volume depletion
0.647 0.353 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.646 0.353 0.000
E23 Hypofunction and other disorders of pituitary gland
0.646 0.354 0.000
I23 Certain current complications following acute myocardial infarction
0.646 0.354 0.000
M25.3 Other instability of joint
0.645 0.354 0.000
M25.2 Flail joint
0.645 0.354 0.000
M25.1 Fistula of joint
0.645 0.354 0.000
I77.1 Stricture of artery
0.644 0.356 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.644 0.356 0.000
C34.9 Bronchus or lung, unspecified
0.642 0.357 0.000
S52 Fracture of forearm
0.642 0.358 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.641 0.359 0.000
C77.2 Intra-abdominal lymph nodes
0.640 0.360 0.000
S17 Crushing injury of neck
0.639 0.360 0.000
S15 Injury of blood vessels at neck level
0.639 0.360 0.000
S14 Injury of nerves and spinal cord at neck level
0.639 0.360 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.639 0.360 0.000
S18 Traumatic amputation at neck level
0.639 0.360 0.000
S16 Injury of muscle and tendon at neck level
0.639 0.360 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.640 0.360 0.000
M76 Enthesopathies of lower limb, excluding foot
0.639 0.360 0.000
M34 Systemic sclerosis
0.639 0.360 0.000
I21.9 Acute myocardial infarction, unspecified
0.639 0.361 0.000
E22 Hyperfunction of pituitary gland
0.639 0.361 0.000
H10 Conjunctivitis
0.638 0.362 0.000
S02.8 Fractures of other skull and facial bones
0.637 0.362 0.000
M88 Paget's disease of bone [osteitis deformans]
0.637 0.363 0.000
S06 Intracranial injury
0.637 0.363 0.000
S89 Other and unspecified injuries of lower leg
0.636 0.363 0.000
C67.9 Bladder, unspecified
0.636 0.364 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.636 0.364 0.000
H50.1 Divergent concomitant strabismus
0.636 0.364 0.000
C54 Malignant neoplasm of corpus uteri
0.636 0.364 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.635 0.365 0.000
I95.8 Other hypotension
0.634 0.366 0.000
I95.0 Idiopathic hypotension
0.634 0.366 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.634 0.366 0.000
C15.5 Lower third of oesophagus
0.634 0.366 0.000
F43 Reaction to severe stress, and adjustment disorders
0.633 0.367 0.000
D37.7 Other digestive organs
0.632 0.368 0.000
B15-B19 Viral hepatitis
0.632 0.368 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.632 0.368 0.000
B37.9 Candidiasis, unspecified
0.631 0.369 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.630 0.370 0.000
F41.1 Generalised anxiety disorder
0.629 0.370 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.630 0.370 0.000
S72 Fracture of femur
0.630 0.370 0.000
S67 Crushing injury of wrist and hand
0.629 0.370 0.000
M86.6 Other chronic osteomyelitis
0.629 0.371 0.000
S86 Injury of muscle and tendon at lower leg level
0.629 0.371 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.629 0.371 0.000
Chapter XXII Codes for special purposes
0.629 0.371 0.000
M24.0 Loose body in joint
0.629 0.371 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.628 0.372 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.628 0.372 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.628 0.372 0.000
C31 Malignant neoplasm of accessory sinuses
0.628 0.372 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.628 0.372 0.000
C37 Malignant neoplasm of thymus
0.628 0.372 0.000
C33 Malignant neoplasm of trachea
0.628 0.372 0.000
H53.1 Subjective visual disturbances
0.627 0.373 0.000
M89 Other disorders of bone
0.627 0.373 0.000
S08 Traumatic amputation of part of head
0.626 0.373 0.000
S07 Crushing injury of head
0.626 0.373 0.000
S04 Injury of cranial nerves
0.626 0.373 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.626 0.373 0.000
S02.1 Fracture of base of skull
0.626 0.374 0.000
W20-W49 Exposure to inanimate mechanical forces
0.626 0.374 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.626 0.374 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.626 0.374 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.626 0.374 0.000
S62.2 Fracture of first metacarpal bone
0.625 0.374 0.000
D37.6 Liver, gallbladder and bile ducts
0.625 0.375 0.000
D37.3 Appendix
0.625 0.375 0.000
D37.2 Small intestine
0.625 0.375 0.000
C77.9 Lymph node, unspecified
0.624 0.376 0.000
M47.1 Other spondylosis with myelopathy
0.623 0.377 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.623 0.377 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.623 0.377 0.000
M62 Other disorders of muscle
0.623 0.377 0.000
C67.1 Dome of bladder
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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