TreeWAS – Variant ID: rs2710323

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F31 Bipolar affective disorder	0.000	0.199	0.801
F31.9 Bipolar affective disorder, unspecified	0.000	0.214	0.786
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.230	0.770
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.249	0.751
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.274	0.726
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.302	0.698
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.305	0.695
F31.7 Bipolar affective disorder, currently in remission	0.000	0.318	0.682
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.352	0.648
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.436	0.564
F31.8 Other bipolar affective disorders	0.000	0.438	0.562
C79.7 Secondary malignant neoplasm of adrenal gland	0.374	0.626	0.000
C79 Secondary malignant neoplasm of other sites	0.338	0.662	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.310	0.690	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.308	0.692	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.284	0.716	0.000
M16.1 Other primary coxarthrosis	0.277	0.723	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.276	0.724	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.272	0.728	0.000
F30-F39 Mood [affective] disorders	0.000	0.731	0.269
M16 Coxarthrosis [arthrosis of hip]	0.259	0.741	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.248	0.752	0.000
F34 Persistent mood [affective] disorders	0.000	0.756	0.244
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.243	0.757	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.241	0.759	0.000
M16.9 Coxarthrosis, unspecified	0.235	0.765	0.000
M16.0 Primary coxarthrosis, bilateral	0.230	0.770	0.000
M06.9 Rheumatoid arthritis, unspecified	0.224	0.776	0.000
M06 Other rheumatoid arthritis	0.224	0.776	0.000
F34.1 Dysthymia	0.000	0.776	0.224
M06.3 Rheumatoid nodule	0.215	0.785	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.215	0.785	0.000
C79.6 Secondary malignant neoplasm of ovary	0.212	0.787	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.212	0.788	0.000
M06.34 Rheumatoid nodule (Hand)	0.204	0.796	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.194	0.805	0.000
M06.4 Inflammatory polyarthropathy	0.189	0.811	0.000
F38 Other mood [affective] disorders	0.000	0.811	0.189
M05-M14 Inflammatory polyarthropathies	0.187	0.813	0.000
M16.3 Other dysplastic coxarthrosis	0.187	0.813	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.185	0.814	0.000
F34.0 Cyclothymia	0.000	0.817	0.183
M06.0 Seronegative rheumatoid arthritis	0.181	0.819	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.179	0.821	0.000
M15-M19 Arthrosis	0.176	0.824	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.825	0.175
F34.8 Other persistent mood [affective] disorders	0.000	0.825	0.175
M05 Seropositive rheumatoid arthritis	0.175	0.825	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.172	0.828	0.000
F30 Manic episode	0.000	0.832	0.168
F32 Depressive episode	0.000	0.832	0.168
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.166	0.834	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.166	0.834	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.163	0.837	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.163	0.837	0.000
M18 Arthrosis of first carpometacarpal joint	0.162	0.838	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.161	0.838	0.000
M06.2 Rheumatoid bursitis	0.161	0.839	0.000
M06.1 Adult-onset Still's disease	0.161	0.839	0.000
M80-M85 Disorders of bone density and structure	0.160	0.840	0.000
M45-M49 Spondylopathies	0.156	0.844	0.000
M16.5 Other posttraumatic coxarthrosis	0.156	0.844	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.155	0.845	0.000
M06.38 Rheumatoid nodule (Other)	0.155	0.845	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.155	0.845	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.155	0.845	0.000
M06.33 Rheumatoid nodule (Forearm)	0.155	0.845	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.155	0.845	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.154	0.846	0.000
M06.8 Other specified rheumatoid arthritis	0.153	0.847	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.152	0.848	0.000
F32.1 Moderate depressive episode	0.000	0.849	0.151
M06.30 Rheumatoid nodule (Multiple sites)	0.150	0.850	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.149	0.850	0.000
M48 Other spondylopathies	0.147	0.853	0.000
M80 Osteoporosis with pathological fracture	0.147	0.853	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.145	0.855	0.000
M85 Other disorders of bone density and structure	0.144	0.856	0.000
F30.0 Hypomania	0.000	0.857	0.143
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.143	0.857	0.000
M81 Osteoporosis without pathological fracture	0.143	0.857	0.000
F39 Unspecified mood [affective] disorder	0.000	0.859	0.141
M06.98 Rheumatoid arthritis, unspecified (Other)	0.138	0.862	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.138	0.862	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.138	0.862	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.137	0.863	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.136	0.863	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.136	0.863	0.000
M81.4 Drug-induced osteoporosis	0.136	0.864	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.136	0.864	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.136	0.864	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.136	0.864	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.136	0.864	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.136	0.864	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.136	0.864	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.136	0.864	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.136	0.864	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.136	0.864	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.864	0.135
F38.1 Other recurrent mood [affective] disorders	0.000	0.864	0.135
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.864	0.136
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.135	0.865	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.134	0.866	0.000
M08 Juvenile arthritis	0.134	0.866	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.134	0.866	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.134	0.866	0.000
M05.2 Rheumatoid vasculitis	0.133	0.867	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.132	0.868	0.000
F38.0 Other single mood [affective] disorders	0.000	0.869	0.131
M49 Spondylopathies in diseases classified elsewhere	0.131	0.869	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.130	0.870	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.130	0.870	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.130	0.870	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.130	0.870	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.130	0.870	0.000
M16.7 Other secondary coxarthrosis	0.130	0.870	0.000
M11 Other crystal arthropathies	0.130	0.870	0.000
M05.8 Other seropositive rheumatoid arthritis	0.130	0.870	0.000
M12 Other specific arthropathies	0.129	0.871	0.000
M48.0 Spinal stenosis	0.127	0.873	0.000
M10 Gout	0.127	0.873	0.000
M05.1 Rheumatoid lung disease	0.126	0.874	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.125	0.874	0.000
M05.0 Felty's syndrome	0.125	0.874	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.123	0.877	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.123	0.877	0.000
M86-M90 Other osteopathies	0.123	0.877	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.122	0.877	0.000
F30.8 Other manic episodes	0.000	0.879	0.121
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.120	0.880	0.000
M14 Arthropathies in other diseases classified elsewhere	0.120	0.880	0.000
M85.6 Other cyst of bone	0.120	0.880	0.000
M85.2 Hyperostosis of skull	0.119	0.881	0.000
M87 Osteonecrosis	0.119	0.881	0.000
M85.0 Fibrous dysplasia (monostotic)	0.119	0.881	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.119	0.881	0.000
F32.0 Mild depressive episode	0.000	0.882	0.118
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.117	0.883	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.117	0.883	0.000
M80.8 Other osteoporosis with pathological fracture	0.117	0.883	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.117	0.883	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.116	0.884	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.116	0.884	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.116	0.884	0.000
M00-M03 Infectious arthropathies	0.116	0.884	0.000
M99 Biomechanical lesions, not elsewhere classified	0.116	0.884	0.000
M87.9 Osteonecrosis, unspecified	0.116	0.884	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.115	0.885	0.000
M06.18 Adult-onset Still's disease (Other)	0.115	0.885	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.115	0.885	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.115	0.885	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.115	0.885	0.000
M06.14 Adult-onset Still's disease (Hand)	0.115	0.885	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.115	0.885	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.115	0.885	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.115	0.885	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.115	0.885	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.115	0.885	0.000
M06.28 Rheumatoid bursitis (Other)	0.115	0.885	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.115	0.885	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.115	0.885	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.115	0.885	0.000
M06.24 Rheumatoid bursitis (Hand)	0.115	0.885	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.115	0.885	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.115	0.885	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.115	0.885	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.115	0.885	0.000
M48.8 Other specified spondylopathies	0.115	0.885	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.114	0.886	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.113	0.887	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.113	0.887	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.113	0.887	0.000
F33 Recurrent depressive disorder	0.000	0.887	0.113
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.112	0.888	0.000
M46 Other inflammatory spondylopathies	0.111	0.888	0.001
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.888	0.112
M48.09 Spinal stenosis (Site unspecified)	0.112	0.888	0.000
M81.8 Other osteoporosis	0.112	0.888	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.111	0.889	0.000
M40-M43 Deforming dorsopathies	0.111	0.889	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.111	0.889	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.110	0.889	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.111	0.889	0.000
M47 Spondylosis	0.110	0.890	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.110	0.890	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.110	0.890	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.110	0.890	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.110	0.890	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.110	0.890	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.110	0.890	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.110	0.890	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.110	0.890	0.000
M83 Adult osteomalacia	0.110	0.890	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.110	0.890	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.109	0.891	0.000
M85.8 Other specified disorders of bone density and structure	0.109	0.891	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.109	0.891	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.107	0.893	0.000
M48.4 Fatigue fracture of vertebra	0.106	0.894	0.000
M48.3 Traumatic spondylopathy	0.106	0.894	0.000
M48.2 Kissing spine	0.106	0.894	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.106	0.894	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.106	0.894	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.106	0.894	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.106	0.894	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.105	0.895	0.000
F30.1 Mania without psychotic symptoms	0.000	0.895	0.105
M10.0 Idiopathic gout	0.104	0.895	0.000
M81.0 Postmenopausal osteoporosis	0.104	0.896	0.000
M47.8 Other spondylosis	0.104	0.896	0.000
F30.9 Manic episode, unspecified	0.000	0.896	0.103
M85.5 Aneurysmal bone cyst	0.104	0.896	0.000
M85.3 Osteitis condensans	0.104	0.896	0.000
M85.1 Skeletal fluorosis	0.104	0.896	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.103	0.897	0.000
M81.6 Localised osteoporosis [Lequesne]	0.102	0.897	0.000
M81.5 Idiopathic osteoporosis	0.102	0.897	0.000
M81.1 Postoophorectomy osteoporosis	0.102	0.897	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.102	0.898	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.102	0.898	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.102	0.898	0.000
M07 Psoriatic and enteropathic arthropathies	0.102	0.898	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.101	0.898	0.000
M85.20 Hyperostosis of skull-Mult sites	0.101	0.898	0.000
M85.4 Solitary bone cyst	0.101	0.899	0.000
F32.8 Other depressive episodes	0.000	0.899	0.101
M45 Ankylosing spondylitis	0.101	0.899	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.100	0.899	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.100	0.900	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.099	0.901	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.099	0.901	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.099	0.901	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.099	0.901	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.099	0.901	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.099	0.901	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.099	0.901	0.000
M81.48 Drug-induced osteoporosis (Other)	0.098	0.902	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.098	0.902	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.098	0.902	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.098	0.902	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.098	0.902	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.098	0.902	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.098	0.902	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.098	0.902	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.902	0.098
F41.9 Anxiety disorder, unspecified	0.000	0.902	0.098
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.097	0.903	0.000
M91-M94 Chondropathies	0.097	0.903	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.097	0.903	0.000
M46.0 Spinal enthesopathy	0.096	0.903	0.001
M08.9 Juvenile arthritis, unspecified	0.096	0.903	0.000
M08.8 Other juvenile arthritis	0.096	0.903	0.000
M08.4 Pauciarticular juvenile arthritis	0.096	0.903	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.096	0.903	0.000
M08.2 Juvenile arthritis with systemic onset	0.096	0.903	0.000
M08.1 Juvenile ankylosing spondylitis	0.096	0.903	0.000
M08.0 Juvenile rheumatoid arthritis	0.096	0.903	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.096	0.903	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.096	0.903	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.096	0.903	0.000
M09.0 Juvenile arthritis in psoriasis	0.096	0.903	0.000
M48.06 Spinal stenosis (Lumbar region)	0.096	0.904	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.096	0.904	0.000
M47.82 Other spondylosis (Cervical region)	0.096	0.904	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.096	0.904	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.096	0.904	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.096	0.904	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.096	0.904	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.096	0.904	0.000
M12.5 Traumatic arthropathy	0.096	0.904	0.000
M05.28 Rheumatoid vasculitis (Other)	0.096	0.904	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.096	0.904	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.096	0.904	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.096	0.904	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.096	0.904	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.096	0.904	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.096	0.904	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.096	0.904	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.096	0.904	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.095	0.904	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.095	0.905	0.000
M48.9 Spondylopathy, unspecified	0.095	0.905	0.000
M11.2 Other chondrocalcinosis	0.095	0.905	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.094	0.906	0.000
M41 Scoliosis	0.094	0.906	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.094	0.906	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.094	0.906	0.000
M49.4 Neuropathic spondylopathy	0.094	0.906	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.094	0.906	0.000
M49.2 Enterobacterial spondylitis	0.094	0.906	0.000
M49.1 Brucella spondylitis	0.094	0.906	0.000
M49.0 Tuberculosis of spine	0.094	0.906	0.000
F30.2 Mania with psychotic symptoms	0.000	0.906	0.094
M11.9 Crystal arthropathy, unspecified	0.094	0.906	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.094	0.906	0.000
M82 Osteoporosis in diseases classified elsewhere	0.093	0.906	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.093	0.906	0.000
M13 Other arthritis	0.094	0.906	0.000
M85.66 Other cyst of bone (Lower leg)	0.093	0.906	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.093	0.907	0.000
M85.68 Other cyst of bone (Other)	0.093	0.907	0.000
M60-M63 Disorders of muscles	0.093	0.907	0.000
Chapter V Mental and behavioural disorders	0.000	0.907	0.093
M11.1 Familial chondrocalcinosis	0.093	0.907	0.000
M11.0 Hydroxyapatite deposition disease	0.093	0.907	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.093	0.907	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.093	0.907	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.093	0.907	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.093	0.907	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.093	0.907	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.093	0.907	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.093	0.907	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.093	0.907	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.093	0.907	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.093	0.907	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.093	0.907	0.000
M12.4 Intermittent hydrarthrosis	0.092	0.907	0.000
M12.1 Kaschin-Beck disease	0.092	0.907	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.092	0.907	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.092	0.908	0.000
M10.3 Gout due to impairment of renal function	0.092	0.908	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.091	0.909	0.000
M12.3 Palindromic rheumatism	0.091	0.909	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.091	0.909	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.091	0.909	0.000
M10.4 Other secondary gout	0.091	0.909	0.000
M10.2 Drug-induced gout	0.091	0.909	0.000
M10.1 Lead-induced gout	0.091	0.909	0.000
M87.1 Osteonecrosis due to drugs	0.091	0.909	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.091	0.909	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.090	0.909	0.000
M05.18 Rheumatoid lung disease (Other)	0.090	0.909	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.090	0.909	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.090	0.909	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.090	0.909	0.000
M05.14 Rheumatoid lung disease (Hand)	0.090	0.909	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.090	0.909	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.090	0.909	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.090	0.909	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.090	0.909	0.000
M05.09 Felty's syndrome (Site unspecified)	0.090	0.910	0.000
M05.08 Felty's syndrome (Other)	0.090	0.910	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.090	0.910	0.000
M05.06 Felty's syndrome (Lower leg)	0.090	0.910	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.090	0.910	0.000
M05.04 Felty's syndrome (Hand)	0.090	0.910	0.000
M05.03 Felty's syndrome (Forearm)	0.090	0.910	0.000
M05.02 Felty's syndrome (Upper arm)	0.090	0.910	0.000
M05.01 Felty's syndrome (Shoulder region)	0.090	0.910	0.000
M05.00 Felty's syndrome (Multiple sites)	0.090	0.910	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.090	0.910	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.090	0.910	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.090	0.910	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.090	0.910	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.090	0.910	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.090	0.910	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.090	0.910	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.090	0.910	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.090	0.910	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.090	0.910	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.090	0.910	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.090	0.910	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.090	0.910	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.089	0.911	0.000
M81.80 Other osteoporosis (Multiple sites)	0.089	0.911	0.000
M87.8 Other osteonecrosis	0.089	0.911	0.000
F99-F99 Unspecified mental disorder	0.000	0.911	0.089
M81.2 Osteoporosis of disuse	0.089	0.911	0.000
M99.8 Other biomechanical lesions	0.088	0.911	0.000
M87.3 Other secondary osteonecrosis	0.088	0.912	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.088	0.912	0.000
M85.9 Disorder of bone density and structure, unspecified	0.088	0.912	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.087	0.913	0.000
M84 Disorders of continuity of bone	0.087	0.913	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.086	0.913	0.001
M12.2 Villonodular synovitis (pigmented)	0.086	0.913	0.000
F41 Other anxiety disorders	0.000	0.913	0.087
M48.87 Other specified spondylopathies (Lumbosacral region)	0.086	0.913	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.914	0.086
F99 Mental disorder, not otherwise specified	0.000	0.914	0.086
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.086	0.914	0.000
M14.4 Arthropathy in amyloidosis	0.086	0.914	0.000
M14.3 Lipoid dermatoarthritis	0.086	0.914	0.000
M14.2 Diabetic arthropathy	0.086	0.914	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.086	0.914	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.086	0.914	0.000
M85.69 Other cyst of bone (Site unspecified)	0.086	0.914	0.000
M85.63 Other cyst of bone (Forearm)	0.086	0.914	0.000
M85.62 Other cyst of bone (Upper arm)	0.086	0.914	0.000
M85.61 Other cyst of bone (Shoulder region)	0.086	0.914	0.000
M85.60 Other cyst of bone (Multiple sites)	0.086	0.914	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.086	0.914	0.000
M85.22 Hyperostosis of skull-Upper arm	0.086	0.914	0.000
M11.8 Other specified crystal arthropathies	0.086	0.914	0.000
M85.29 Hyperostosis of skull-Site unspec	0.086	0.914	0.000
M85.28 Hyperostosis of skull-Other	0.086	0.914	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.086	0.914	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.086	0.914	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.086	0.914	0.000
M85.24 Hyperostosis of skull-Hand	0.086	0.914	0.000
M85.23 Hyperostosis of skull-Forearm	0.086	0.914	0.000
M85.21 Hyperostosis of skull-Shldr region	0.086	0.914	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.086	0.914	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.085	0.914	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.085	0.914	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.085	0.914	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.085	0.914	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.085	0.914	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.085	0.914	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.085	0.914	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.085	0.914	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.085	0.914	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.085	0.914	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.085	0.914	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.085	0.915	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.085	0.915	0.000
M46.4 Discitis, unspecified	0.084	0.916	0.001
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.084	0.916	0.000
M47.84 Other spondylosis (Thoracic region)	0.084	0.916	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.084	0.916	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.084	0.916	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.084	0.916	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.084	0.916	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.084	0.916	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.084	0.916	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.084	0.916	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.084	0.916	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.083	0.917	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.083	0.917	0.000
M99.9 Biomechanical lesion, unspecified	0.083	0.917	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.083	0.917	0.000
M99.4 Connective tissue stenosis of neural canal	0.083	0.917	0.000
M99.3 Osseous stenosis of neural canal	0.083	0.917	0.000
M99.2 Subluxation stenosis of neural canal	0.083	0.917	0.000
M99.1 Subluxation complex (vertebral)	0.083	0.917	0.000
M99.0 Segmental and somatic dysfunction	0.083	0.917	0.000
M87.2 Osteonecrosis due to previous trauma	0.083	0.917	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.083	0.917	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.083	0.917	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.083	0.917	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.083	0.917	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.083	0.917	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.083	0.917	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.083	0.917	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.083	0.917	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.083	0.917	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.083	0.917	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.083	0.917	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.083	0.917	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.082	0.917	0.001
M02 Reactive arthropathies	0.082	0.917	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.082	0.918	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.082	0.918	0.000
M47.89 Other spondylosis (Site unspecified)	0.082	0.918	0.000
M10.06 Idiopathic gout (Lower leg)	0.082	0.918	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.082	0.918	0.000
M10.02 Idiopathic gout (Upper arm)	0.081	0.918	0.000
M46.2 Osteomyelitis of vertebra	0.081	0.919	0.001
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.081	0.919	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.081	0.919	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.081	0.919	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.081	0.919	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.081	0.919	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.081	0.919	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.081	0.919	0.000
C79.2 Secondary malignant neoplasm of skin	0.081	0.919	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.081	0.919	0.000
M85.64 Other cyst of bone (Hand)	0.081	0.919	0.000
M46.8 Other specified inflammatory spondylopathies	0.080	0.919	0.001
M46.5 Other infective spondylopathies	0.080	0.919	0.001
M00 Pyogenic arthritis	0.080	0.920	0.000
M81.89 Other osteoporosis (Site unspecified)	0.080	0.920	0.000
M81.88 Other osteoporosis (Other)	0.080	0.920	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.080	0.920	0.000
M81.86 Other osteoporosis (Lower leg)	0.080	0.920	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.080	0.920	0.000
M81.84 Other osteoporosis (Hand)	0.080	0.920	0.000
M81.83 Other osteoporosis (Forearm)	0.080	0.920	0.000
M81.82 Other osteoporosis (Upper arm)	0.080	0.920	0.000
M81.81 Other osteoporosis (Shoulder region)	0.080	0.920	0.000
M42 Spinal osteochondrosis	0.080	0.920	0.000
M83.1 Senile osteomalacia	0.079	0.920	0.000
M92 Other juvenile osteochondrosis	0.079	0.920	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.079	0.921	0.000
M83.3 Adult osteomalacia due to malnutrition	0.079	0.921	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.079	0.921	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.079	0.921	0.000
M83.9 Adult osteomalacia, unspecified	0.079	0.921	0.000
M83.5 Other drug-induced osteomalacia in adults	0.079	0.921	0.000
M83.4 Aluminum bone disease	0.079	0.921	0.000
M83.2 Adult osteomalacia due to malabsorption	0.079	0.921	0.000
M83.0 Puerperal osteomalacia	0.079	0.921	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.079	0.921	0.000
M90 Osteopathies in diseases classified elsewhere	0.079	0.921	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.078	0.921	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.078	0.921	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.078	0.922	0.000
F33.8 Other recurrent depressive disorders	0.000	0.922	0.078
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.078	0.922	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.078	0.922	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations