TreeWAS – Variant ID: rs2735062

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.002	0.998
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.043	0.957
G37 Other demyelinating diseases of central nervous system	0.000	0.052	0.948
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.069	0.931
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.140	0.860
G36 Other acute disseminated demyelination	0.000	0.302	0.698
G37.5 Concentric sclerosis [Balo]	0.000	0.320	0.680
G37.4 Subacute necrotising myelitis	0.000	0.320	0.680
G37.2 Central pontine myelinolysis	0.000	0.320	0.680
G37.1 Central demyelination of corpus callosum	0.000	0.320	0.680
G37.0 Diffuse sclerosis	0.000	0.320	0.680
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.359	0.641
I84.9 Unspecified haemorrhoids without complication	0.550	0.450	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.487	0.513
G36.9 Acute disseminated demyelination, unspecified	0.000	0.499	0.501
G36.8 Other specified acute disseminated demyelination	0.000	0.499	0.501
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.499	0.501
E05.9 Thyrotoxicosis, unspecified	0.000	0.610	0.390
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.614	0.386
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.626	0.374
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.653	0.347
E00-E07 Disorders of thyroid gland	0.000	0.699	0.301
E06 Thyroiditis	0.000	0.701	0.299
K90 Intestinal malabsorption	0.000	0.705	0.295
E06.3 Autoimmune thyroiditis	0.000	0.713	0.287
E05.5 Thyroid crisis or storm	0.000	0.723	0.277
E05.4 Thyrotoxicosis factitia	0.000	0.723	0.277
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.723	0.277
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.723	0.277
E06.9 Thyroiditis, unspecified	0.000	0.725	0.275
E05.8 Other thyrotoxicosis	0.000	0.745	0.255
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.755	0.245
E06.5 Other chronic thyroiditis	0.000	0.771	0.229
E07 Other disorders of thyroid	0.000	0.776	0.224
E03 Other hypothyroidism	0.000	0.779	0.221
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.784	0.216
E00 Congenital iodine-deficiency syndrome	0.000	0.784	0.216
K90.8 Other intestinal malabsorption	0.000	0.785	0.215
E06.4 Drug-induced thyroiditis	0.000	0.786	0.214
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.786	0.214
E06.0 Acute thyroiditis	0.000	0.786	0.214
K90.3 Pancreatic steatorrhoea	0.000	0.788	0.212
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.788	0.212
K90.1 Tropical sprue	0.000	0.788	0.212
K90.9 Intestinal malabsorption, unspecified	0.000	0.794	0.206
E06.1 Subacute thyroiditis	0.000	0.801	0.199
S06.3 Focal brain injury	0.000	0.816	0.184
E07.8 Other specified disorders of thyroid	0.000	0.817	0.183
M35.0 Sicca syndrome [Sjogren]	0.000	0.821	0.179
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.822	0.178
E03.9 Hypothyroidism, unspecified	0.000	0.822	0.178
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.835	0.165
E07.1 Dyshormogenetic goitre	0.000	0.839	0.161
E07.0 Hypersecretion of calcitonin	0.000	0.839	0.161
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.841	0.159
E03.5 Myxoedema coma	0.000	0.841	0.159
E03.4 Atrophy of thyroid (acquired)	0.000	0.841	0.159
E03.3 Postinfectious hypothyroidism	0.000	0.841	0.159
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.845	0.155
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.845	0.155
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.845	0.155
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.845	0.155
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.845	0.155
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.845	0.155
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.845	0.155
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.845	0.155
E83 Disorders of mineral metabolism	0.000	0.852	0.148
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.855	0.145
E07.9 Disorder of thyroid, unspecified	0.000	0.860	0.140
S06 Intracranial injury	0.000	0.860	0.140
E03.8 Other specified hypothyroidism	0.000	0.863	0.137
S06.5 Traumatic subdural haemorrhage	0.000	0.868	0.132
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.868	0.132
E03.1 Congenital hypothyroidism without goitre	0.000	0.869	0.131
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.872	0.128
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.878	0.122
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.883	0.117
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.891	0.109
S06.1 Traumatic cerebral oedema	0.000	0.893	0.107
E83.8 Other disorders of mineral metabolism	0.000	0.894	0.106
E83.2 Disorders of zinc metabolism	0.000	0.894	0.106
E83.0 Disorders of copper metabolism	0.000	0.894	0.106
E83.3 Disorders of phosphorus metabolism	0.000	0.898	0.102
S06.7 Intracranial injury with prolonged coma	0.000	0.900	0.100
I71 Aortic aneurysm and dissection	0.000	0.900	0.100
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.900	0.099
S06.9 Intracranial injury, unspecified	0.000	0.901	0.099
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.905	0.095
S06.4 Epidural haemorrhage	0.000	0.906	0.094
E83.5 Disorders of calcium metabolism	0.000	0.911	0.089
S06.2 Diffuse brain injury	0.000	0.911	0.089
S06.0 Concussion	0.000	0.912	0.088
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.912	0.087
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.913	0.087
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.915	0.085
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.917	0.083
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.917	0.083
S06.8 Other intracranial injuries	0.000	0.917	0.082
I72 Other aneurysm	0.000	0.920	0.080
I73 Other peripheral vascular diseases	0.000	0.921	0.079
I73.9 Peripheral vascular disease, unspecified	0.000	0.922	0.078
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.923	0.077
I72.4 Aneurysm of artery of lower extremity	0.000	0.925	0.075
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.928	0.072
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.928	0.072
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.928	0.072
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.928	0.072
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.928	0.072
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.929	0.071
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.931	0.069
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.931	0.069
I74 Arterial embolism and thrombosis	0.000	0.932	0.068
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.932	0.068
I72.9 Aneurysm of unspecified site	0.000	0.933	0.067
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.934	0.066
I70 Atherosclerosis	0.000	0.936	0.064
I72.1 Aneurysm of artery of upper extremity	0.000	0.936	0.064
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.936	0.064
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.936	0.064
S06.01 Concussion (with open intracranial wound)	0.000	0.937	0.063
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.938	0.062
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.939	0.061
I74.8 Embolism and thrombosis of other arteries	0.000	0.939	0.061
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.939	0.061
I72.8 Aneurysm of other specified arteries	0.000	0.940	0.060
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.940	0.059
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.942	0.058
I71.0 Dissection of aorta [any part]	0.000	0.943	0.057
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.943	0.057
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.943	0.057
I72.2 Aneurysm of renal artery	0.000	0.944	0.056
K50.9 Crohn's disease, unspecified	0.055	0.945	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.946	0.054
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.946	0.054
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.946	0.054
I73.8 Other specified peripheral vascular diseases	0.000	0.947	0.053
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.948	0.052
I79.1 Aortitis in diseases classified elsewhere	0.000	0.948	0.052
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.948	0.052
S06.00 Concussion (without open intracranial wound)	0.000	0.949	0.050
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.949	0.050
I72.3 Aneurysm of iliac artery	0.000	0.951	0.049
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.953	0.047
I70.1 Atherosclerosis of renal artery	0.000	0.953	0.047
E04 Other non-toxic goitre	0.000	0.953	0.046
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.953	0.046
K50 Crohn's disease [regional enteritis]	0.047	0.953	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.954	0.046
M35 Other systemic involvement of connective tissue	0.000	0.954	0.046
I70.9 Generalised and unspecified atherosclerosis	0.000	0.955	0.045
I72.0 Aneurysm of carotid artery	0.000	0.955	0.045
I70.0 Atherosclerosis of aorta	0.000	0.956	0.044
K50.8 Other Crohn's disease	0.044	0.956	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.957	0.043
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.958	0.041
M35.7 Hypermobility syndrome	0.000	0.960	0.040
I77 Other disorders of arteries and arterioles	0.000	0.960	0.040
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.961	0.039
K51.2 Ulcerative (chronic) proctitis	0.037	0.963	0.000
I73.0 Raynaud's syndrome	0.000	0.963	0.037
I77.2 Rupture of artery	0.000	0.964	0.036
K51 Ulcerative colitis	0.036	0.964	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.964	0.036
E04.0 Non-toxic diffuse goitre	0.000	0.965	0.035
K50-K52 Noninfective enteritis and colitis	0.035	0.965	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.966	0.034
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.966	0.034
E04.8 Other specified non-toxic goitre	0.000	0.966	0.033
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.967	0.033
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.967	0.033
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.967	0.033
M35.5 Multifocal fibrosclerosis	0.000	0.967	0.033
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.967	0.033
K51.0 Ulcerative (chronic) enterocolitis	0.033	0.967	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.967	0.032
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.968	0.032
E89.0 Postprocedural hypothyroidism	0.000	0.968	0.032
K50.1 Crohn's disease of large intestine	0.031	0.968	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.969	0.031
I77.8 Other specified disorders of arteries and arterioles	0.000	0.969	0.031
M35.8 Other specified systemic involvement of connective tissue	0.000	0.969	0.031
M35.1 Other overlap syndromes	0.000	0.970	0.030
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.970	0.030
E70-E90 Metabolic disorders	0.000	0.970	0.030
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.970	0.030
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.971	0.029
I77.5 Necrosis of artery	0.000	0.971	0.029
I77.4 Coeliac artery compression syndrome	0.000	0.971	0.029
I77.3 Arterial fibromuscular dysplasia	0.000	0.971	0.029
K51.1 Ulcerative (chronic) ileocolitis	0.028	0.972	0.000
M35.2 Behcet's disease	0.000	0.972	0.028
K51.8 Other ulcerative colitis	0.028	0.972	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.972	0.028
K51.5 Mucosal proctocolitis	0.027	0.973	0.000
K51.4 Pseudopolyposis of colon	0.026	0.974	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.975	0.025
E40-E46 Malnutrition	0.000	0.975	0.025
I78 Diseases of capillaries	0.000	0.976	0.024
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.976	0.024
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.976	0.024
K90-K93 Other diseases of the digestive system	0.000	0.977	0.023
E89.4 Postprocedural ovarian failure	0.000	0.978	0.022
E46 Unspecified protein-energy malnutrition	0.000	0.978	0.022
E70 Disorders of aromatic amino-acid metabolism	0.000	0.978	0.022
I77.6 Arteritis, unspecified	0.000	0.978	0.022
E77 Disorders of glycoprotein metabolism	0.000	0.978	0.022
E76 Disorders of glycosaminoglycan metabolism	0.000	0.978	0.022
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.978	0.022
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.978	0.022
K50.0 Crohn's disease of small intestine	0.022	0.978	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.979	0.021
E89.1 Postprocedural hypoinsulinaemia	0.000	0.979	0.021
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.979	0.021
E73 Lactose intolerance	0.000	0.979	0.021
K51.9 Ulcerative colitis, unspecified	0.021	0.979	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.980	0.020
I77.0 Arteriovenous fistula, acquired	0.000	0.980	0.020
E84 Cystic fibrosis	0.000	0.980	0.020
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.980	0.020
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.980	0.020
I74.5 Embolism and thrombosis of iliac artery	0.000	0.980	0.020
E72 Other disorders of amino-acid metabolism	0.000	0.981	0.019
E04.9 Non-toxic goitre, unspecified	0.000	0.981	0.019
E79 Disorders of purine and pyrimidine metabolism	0.000	0.981	0.019
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.982	0.018
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.982	0.018
E45 Retarded development following protein-energy malnutrition	0.000	0.982	0.018
E43 Unspecified severe protein-energy malnutrition	0.000	0.982	0.018
E42 Marasmic kwashiorkor	0.000	0.982	0.018
E41 Nutritional marasmus	0.000	0.982	0.018
E40 Kwashiorkor	0.000	0.982	0.018
E80.6 Other disorders of bilirubin metabolism	0.000	0.983	0.017
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.983	0.017
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.984	0.016
E75.5 Other lipid storage disorders	0.000	0.984	0.016
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.013	0.984	0.003
E70.3 Albinism	0.000	0.984	0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.984	0.016
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.984	0.016
E70.2 Disorders of tyrosine metabolism	0.000	0.984	0.016
E70.1 Other hyperphenylalaninaemias	0.000	0.984	0.016
E70.0 Classical phenylketonuria	0.000	0.984	0.016
E89.5 Postprocedural testicular hypofunction	0.000	0.984	0.016
E71.3 Disorders of fatty-acid metabolism	0.000	0.984	0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.984	0.016
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.984	0.016
E71.0 Maple-syrup-urine disease	0.000	0.984	0.016
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.984	0.016
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.984	0.016
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.984	0.016
E76.2 Other mucopolysaccharidoses	0.000	0.984	0.016
E76.1 Mucopolysaccharidosis, type II	0.000	0.984	0.016
E76.0 Mucopolysaccharidosis, type I	0.000	0.984	0.016
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.984	0.016
E77.8 Other disorders of glycoprotein metabolism	0.000	0.984	0.016
E77.1 Defects in glycoprotein degradation	0.000	0.984	0.016
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.984	0.016
I78.9 Disease of capillaries, unspecified	0.000	0.984	0.016
K51.3 Ulcerative (chronic) rectosigmoiditis	0.016	0.984	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.985	0.015
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.985	0.015
E75.3 Sphingolipidosis, unspecified	0.000	0.985	0.015
E75.1 Other gangliosidosis	0.000	0.985	0.015
E75.0 GM2 gangliosidosis	0.000	0.985	0.015
E73.8 Other lactose intolerance	0.000	0.985	0.015
E73.1 Secondary lactase deficiency	0.000	0.985	0.015
E73.0 Congenital lactase deficiency	0.000	0.985	0.015
E80.1 Porphyria cutanea tarda	0.000	0.985	0.015
R31 Unspecified haematuria	0.015	0.985	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.985	0.015
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.985	0.015
G61 Inflammatory polyneuropathy	0.014	0.985	0.001
E04.2 Non-toxic multinodular goitre	0.000	0.985	0.015
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.985	0.015
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.985	0.015
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.985	0.015
E74.2 Disorders of galactose metabolism	0.000	0.985	0.015
E74.1 Disorders of fructose metabolism	0.000	0.985	0.015
E73.9 Lactose intolerance, unspecified	0.000	0.985	0.015
G63 Polyneuropathy in diseases classified elsewhere	0.013	0.985	0.001
G60.0 Hereditary motor and sensory neuropathy	0.014	0.985	0.000
E84.8 Cystic fibrosis with other manifestations	0.000	0.985	0.014
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.985	0.014
G60 Hereditary and idiopathic neuropathy	0.013	0.985	0.002
G61.0 Guillain-Barre syndrome	0.014	0.985	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.985	0.014
E80.5 Crigler-Najjar syndrome	0.000	0.985	0.014
E80.3 Defects of catalase and peroxydase	0.000	0.985	0.014
E80.0 Hereditary erythropoietic porphyria	0.000	0.985	0.014
E74.0 Glycogen storage disease	0.000	0.986	0.014
G63.2 Diabetic polyneuropathy	0.014	0.986	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.986	0.014
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.986	0.014
E72.5 Disorders of glycine metabolism	0.000	0.986	0.014
E72.4 Disorders of ornithine metabolism	0.000	0.986	0.014
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.986	0.014
E72.2 Disorders of urea cycle metabolism	0.000	0.986	0.014
E88 Other metabolic disorders	0.000	0.986	0.014
E72.0 Disorders of amino-acid transport	0.000	0.986	0.014
E75.2 Other sphingolipidosis	0.000	0.986	0.014
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.986	0.014
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.986	0.013
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.986	0.013
E79.1 Lesch-Nyhan syndrome	0.000	0.986	0.013
I78.1 Naevus, nonneoplastic	0.000	0.987	0.013
E44.1 Mild protein-energy malnutrition	0.000	0.987	0.013
E44.0 Moderate protein-energy malnutrition	0.000	0.987	0.013
I78.8 Other diseases of capillaries	0.000	0.987	0.013
B37.9 Candidiasis, unspecified	0.000	0.987	0.013
E89.3 Postprocedural hypopituitarism	0.000	0.987	0.013
A08.4 Viral intestinal infection, unspecified	0.000	0.987	0.013
E80.2 Other porphyria	0.000	0.987	0.013
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.988	0.012
G61.8 Other inflammatory polyneuropathies	0.012	0.988	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.988	0.012
K93.1 Megacolon in Chagas' disease	0.000	0.988	0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.988	0.012
M35.3 Polymyalgia rheumatica	0.000	0.988	0.012
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.988	0.012
G64 Other disorders of peripheral nervous system	0.009	0.988	0.002
G61.9 Inflammatory polyneuropathy, unspecified	0.011	0.988	0.001
B37 Candidiasis	0.000	0.988	0.012
E15 Nondiabetic hypoglycaemic coma	0.000	0.989	0.011
B37.8 Candidiasis of other sites	0.000	0.989	0.011
E65-E68 Obesity and other hyperalimentation	0.000	0.989	0.011
E88.9 Metabolic disorder, unspecified	0.000	0.989	0.011
E86 Volume depletion	0.000	0.989	0.011
G61.1 Serum neuropathy	0.010	0.989	0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.989	0.010
G63.8 Polyneuropathy in other diseases classified elsewhere	0.010	0.989	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.010	0.989	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.010	0.989	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.010	0.989	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.010	0.989	0.001
G63.1 Polyneuropathy in neoplastic disease	0.010	0.989	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.010	0.989	0.001
I77.1 Stricture of artery	0.000	0.989	0.011
B37.3 Candidiasis of vulva and vagina	0.000	0.989	0.011
B37.0 Candidal stomatitis	0.000	0.989	0.011
G60.3 Idiopathic progressive neuropathy	0.010	0.989	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.010	0.989	0.001
G60.1 Refsum's disease	0.010	0.989	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.989	0.010
N76 Other inflammation of vagina and vulva	0.000	0.989	0.011
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.009	0.990	0.001
E88.2 Lipomatosis, not elsewhere classified	0.000	0.990	0.010
N76.8 Other specified inflammation of vagina and vulva	0.000	0.990	0.010
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.990	0.010
N76.2 Acute vulvitis	0.000	0.990	0.010
N76.3 Subacute and chronic vulvitis	0.000	0.990	0.010
E88.3 Tumour lysis syndrome	0.000	0.990	0.010
E80.4 Gilbert's syndrome	0.000	0.990	0.010
N76.4 Abscess of vulva	0.000	0.990	0.009
B37.7 Candidal septicaemia	0.000	0.991	0.009
E85 Amyloidosis	0.001	0.991	0.008
G60.8 Other hereditary and idiopathic neuropathies	0.008	0.991	0.001
E88.8 Other specified metabolic disorders	0.000	0.991	0.009
N76.0 Acute vaginitis	0.000	0.991	0.009
E27.1 Primary adrenocortical insufficiency	0.000	0.991	0.009
G62 Other polyneuropathies	0.005	0.991	0.003
E50-E64 Other nutritional deficiencies	0.000	0.991	0.009
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.991	0.009
B37.6 Candidal endocarditis	0.000	0.991	0.009
B37.5 Candidal meningitis	0.000	0.991	0.009
E67 Other hyperalimentation	0.000	0.992	0.008
E68 Sequelae of hyperalimentation	0.000	0.992	0.008
N76.1 Subacute and chronic vaginitis	0.000	0.992	0.008
N76.5 Ulceration of vagina	0.000	0.992	0.008
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
B37.2 Candidiasis of skin and nail	0.000	0.992	0.008
B37.4 Candidiasis of other urogenital sites	0.000	0.992	0.008
G30-G32 Other degenerative diseases of the nervous system	0.000	0.992	0.008
Chapter VI Diseases of the nervous system	0.000	0.992	0.008
E85.8 Other amyloidosis	0.001	0.993	0.006
H21.8 Other specified disorders of iris and ciliary body	0.007	0.993	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.993	0.006
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.993	0.006
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.993	0.006
E51 Thiamine deficiency	0.000	0.993	0.007
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.993	0.007
E65 Localised adiposity	0.000	0.993	0.007
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.993	0.007
E56 Other vitamin deficiencies	0.000	0.993	0.007
G62.2 Polyneuropathy due to other toxic agents	0.004	0.993	0.003
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.993	0.006
E63 Other nutritional deficiencies	0.000	0.993	0.006
E50 Vitamin A deficiency	0.000	0.993	0.006
E60 Dietary zinc deficiency	0.000	0.993	0.006
E59 Dietary selenium deficiency	0.000	0.993	0.006
E52 Niacin deficiency [pellagra]	0.000	0.993	0.006
E04.1 Non-toxic single thyroid nodule	0.000	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.000	0.994	0.006
E67.8 Other specified hyperalimentation	0.000	0.994	0.006
E67.3 Hypervitaminosis D	0.000	0.994	0.006
E67.2 Megavitamin-B6 syndrome	0.000	0.994	0.006
E67.1 Hypercarotenaemia	0.000	0.994	0.006
E67.0 Hypervitaminosis A	0.000	0.994	0.006
G31.8 Other specified degenerative diseases of nervous system	0.000	0.994	0.006
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.994	0.006
G31.0 Circumscribed brain atrophy	0.000	0.994	0.006
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.994	0.006
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.994	0.006
G30 Alzheimer's disease	0.000	0.994	0.006
G62.0 Drug-induced polyneuropathy	0.004	0.994	0.002
E27 Other disorders of adrenal gland	0.000	0.994	0.006
E54 Ascorbic acid deficiency	0.000	0.994	0.006
G31.2 Degeneration of nervous system due to alcohol	0.000	0.994	0.006
G62.1 Alcoholic polyneuropathy	0.002	0.994	0.003
E58 Dietary calcium deficiency	0.000	0.994	0.006
N76.6 Ulceration of vulva	0.000	0.994	0.006
E20 Hypoparathyroidism	0.000	0.994	0.006
E51.2 Wernicke's encephalopathy	0.000	0.994	0.006
E85.3 Secondary systemic amyloidosis	0.001	0.994	0.005
G62.8 Other specified polyneuropathies	0.005	0.994	0.001
G30.0 Alzheimer's disease with early onset	0.000	0.994	0.006
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.994	0.006
B37.1 Pulmonary candidiasis	0.000	0.994	0.005
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.994	0.006
E25 Adrenogenital disorders	0.000	0.994	0.005
G70-G73 Diseases of myoneural junction and muscle	0.000	0.995	0.005
E20.9 Hypoparathyroidism, unspecified	0.000	0.995	0.005
E51.9 Thiamine deficiency, unspecified	0.000	0.995	0.005
E51.8 Other manifestations of thiamine deficiency	0.000	0.995	0.005
E51.1 Beriberi	0.000	0.995	0.005
E55 Vitamin D deficiency	0.000	0.995	0.005
K91.1 Postgastric surgery syndromes	0.000	0.995	0.005
E56.1 Deficiency of vitamin K	0.000	0.995	0.005
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.995	0.005
E56.9 Vitamin deficiency, unspecified	0.000	0.995	0.005
E56.8 Deficiency of other vitamins	0.000	0.995	0.005
E56.0 Deficiency of vitamin E	0.000	0.995	0.005
E23 Hypofunction and other disorders of pituitary gland	0.000	0.995	0.005
H53.2 Diplopia	0.000	0.995	0.005
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.995	0.005
Z74.0 Reduced mobility	0.000	0.995	0.005
E50.9 Vitamin A deficiency, unspecified	0.000	0.995	0.005
E50.8 Other manifestations of vitamin A deficiency	0.000	0.995	0.005
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.995	0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.995	0.005
E50.5 Vitamin A deficiency with night blindness	0.000	0.995	0.005
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.995	0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.995	0.005
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.995	0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.995	0.005
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.995	0.005
E63.9 Nutritional deficiency, unspecified	0.000	0.995	0.005
E63.8 Other specified nutritional deficiencies	0.000	0.995	0.005
E63.1 Imbalance of constituents of food intake	0.000	0.995	0.005
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.995	0.005
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.995	0.005
E64.8 Sequelae of other nutritional deficiencies	0.000	0.995	0.005
E64.3 Sequelae of rickets	0.000	0.995	0.005
E64.2 Sequelae of vitamin C deficiency	0.000	0.995	0.005
E64.1 Sequelae of vitamin A deficiency	0.000	0.995	0.005
E64.0 Sequelae of protein-energy malnutrition	0.000	0.995	0.005
E16 Other disorders of pancreatic internal secretion	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.995	0.005
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.995	0.005
E85.4 Organ-limited amyloidosis	0.001	0.995	0.004
A08 Viral and other specified intestinal infections	0.000	0.995	0.005
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.995	0.005
G30.9 Alzheimer's disease, unspecified	0.000	0.995	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.995	0.005
E32 Diseases of thymus	0.000	0.995	0.005
E31 Polyglandular dysfunction	0.000	0.995	0.005
E30 Disorders of puberty, not elsewhere classified	0.000	0.995	0.005
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.995	0.005
H21 Other disorders of iris and ciliary body	0.005	0.995	0.000
G70 Myasthenia gravis and other myoneural disorders	0.000	0.995	0.005
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.995	0.005
E23.6 Other disorders of pituitary gland	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
H21.0 Hyphaema	0.005	0.995	0.000
C32.0 Glottis	0.005	0.995	0.000
J15.1 Pneumonia due to Pseudomonas	0.005	0.995	0.000
S00-S09 Injuries to the head	0.000	0.995	0.005
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.995	0.004
G62.9 Polyneuropathy, unspecified	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.004
E27.0 Other adrenocortical overactivity	0.000	0.995	0.004
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.995	0.005
S46.3 Injury of muscle and tendon of triceps	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.000	0.996	0.004
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.004
E26 Hyperaldosteronism	0.000	0.996	0.004
E85.9 Amyloidosis, unspecified	0.002	0.996	0.003
L43.9 Lichen planus, unspecified	0.000	0.996	0.004
H73.8 Other specified disorders of tympanic membrane	0.004	0.996	0.000
A08.3 Other viral enteritis	0.000	0.996	0.004
K91.5 Postcholecystectomy syndrome	0.000	0.996	0.004
G72 Other myopathies	0.000	0.996	0.004
G70.0 Myasthenia gravis	0.000	0.996	0.004
H21.1 Other vascular disorders of iris and ciliary body	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.004
E25.8 Other adrenogenital disorders	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations