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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2780226
log Bayes Factor = 5.10037
Chromosome 6   position 34,199,092  (GRCh37) Explore rs2780226 on Ensembl!
Variant rs2780226 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N40-N51 Diseases of male genital organs
0.999 0.001 0.000
N40 Hyperplasia of prostate
0.998 0.002 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.998 0.002 0.000
I34 Nonrheumatic mitral valve disorders
0.996 0.004 0.000
E21.0 Primary hyperparathyroidism
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.991 0.009 0.000
I34.0 Mitral (valve) insufficiency
0.987 0.013 0.000
E10-E14 Diabetes mellitus
0.985 0.015 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.982 0.018 0.000
N20-N23 Urolithiasis
0.981 0.019 0.000
E14 Unspecified diabetes mellitus
0.974 0.026 0.000
E14.9 Without complications
0.965 0.035 0.000
N41 Inflammatory diseases of prostate
0.963 0.037 0.000
I10-I15 Hypertensive diseases
0.959 0.041 0.000
N21 Calculus of lower urinary tract
0.952 0.048 0.000
I10 Essential (primary) hypertension
0.950 0.050 0.000
N10-N16 Renal tubulo-interstitial diseases
0.941 0.059 0.000
I77 Other disorders of arteries and arterioles
0.935 0.065 0.000
N13 Obstructive and reflux uropathy
0.933 0.067 0.000
Chapter I Certain infectious and parasitic diseases
0.931 0.069 0.000
I49 Other cardiac arrhythmias
0.931 0.069 0.000
Chapter VIII Diseases of the ear and mastoid process
0.931 0.069 0.000
I45 Other conduction disorders
0.930 0.070 0.000
E27 Other disorders of adrenal gland
0.928 0.072 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.917 0.083 0.000
N21.0 Calculus in bladder
0.915 0.085 0.000
E21.3 Hyperparathyroidism, unspecified
0.914 0.086 0.000
N41.1 Chronic prostatitis
0.913 0.087 0.000
N20 Calculus of kidney and ureter
0.910 0.090 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.907 0.093 0.000
N13.3 Other and unspecified hydronephrosis
0.904 0.096 0.000
I77.6 Arteritis, unspecified
0.901 0.099 0.000
I74 Arterial embolism and thrombosis
0.900 0.100 0.000
H90-H95 Other disorders of ear
0.900 0.100 0.000
A30-A49 Other bacterial diseases
0.899 0.101 0.000
I20-I25 Ischaemic heart diseases
0.896 0.104 0.000
I71 Aortic aneurysm and dissection
0.893 0.107 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.893 0.107 0.000
E10 Insulin-dependent diabetes mellitus
0.893 0.107 0.000
I50 Heart failure
0.888 0.112 0.000
I34.1 Mitral (valve) prolapse
0.888 0.112 0.000
N41.0 Acute prostatitis
0.874 0.126 0.000
I49.5 Sick sinus syndrome
0.866 0.134 0.000
N00-N08 Glomerular diseases
0.863 0.137 0.000
I50.0 Congestive heart failure
0.860 0.140 0.000
F60-F69 Disorders of adult personality and behaviour
0.859 0.141 0.000
F17.1 Harmful use
0.858 0.142 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.857 0.143 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.854 0.146 0.000
I72 Other aneurysm
0.853 0.147 0.000
F10.3 Withdrawal state
0.848 0.152 0.000
H90 Conductive and sensorineural hearing loss
0.838 0.162 0.000
I25 Chronic ischaemic heart disease
0.837 0.163 0.000
E24 Cushing's syndrome
0.835 0.165 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.835 0.165 0.000
N13.4 Hydroureter
0.832 0.168 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.824 0.176 0.000
E25 Adrenogenital disorders
0.824 0.176 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.819 0.181 0.000
L60-L75 Disorders of skin appendages
0.818 0.182 0.000
N42 Other disorders of prostate
0.816 0.184 0.000
A46 Erysipelas
0.816 0.184 0.000
I25.1 Atherosclerotic heart disease
0.815 0.185 0.000
I77.1 Stricture of artery
0.815 0.185 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.813 0.187 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.812 0.188 0.000
A40 Streptococcal septicaemia
0.810 0.190 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.808 0.192 0.000
E26 Hyperaldosteronism
0.805 0.195 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.804 0.196 0.000
L72.0 Epidermal cyst
0.804 0.196 0.000
L82 Seborrhoeic keratosis
0.803 0.197 0.000
H90.2 Conductive hearing loss, unspecified
0.801 0.199 0.000
A49 Bacterial infection of unspecified site
0.799 0.201 0.000
H92 Otalgia and effusion of ear
0.798 0.202 0.000
I70 Atherosclerosis
0.796 0.204 0.000
I35 Nonrheumatic aortic valve disorders
0.790 0.210 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.788 0.212 0.000
N20.1 Calculus of ureter
0.785 0.215 0.000
I49.8 Other specified cardiac arrhythmias
0.784 0.216 0.000
I45.5 Other specified heart block
0.782 0.218 0.000
I47 Paroxysmal tachycardia
0.781 0.219 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.780 0.220 0.000
I30 Acute pericarditis
0.780 0.220 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.778 0.222 0.000
I49.1 Atrial premature depolarisation
0.777 0.223 0.000
I45.6 Preexcitation syndrome
0.777 0.223 0.000
I74.8 Embolism and thrombosis of other arteries
0.775 0.225 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.775 0.225 0.000
N03 Chronic nephritic syndrome
0.774 0.225 0.000
E28 Ovarian dysfunction
0.774 0.226 0.000
E14.4 With neurological complications
0.772 0.228 0.000
F10.4 Withdrawal state with delirium
0.771 0.229 0.000
I51 Complications and ill-defined descriptions of heart disease
0.771 0.229 0.000
E10.0 With coma
0.769 0.231 0.000
N20.0 Calculus of kidney
0.767 0.233 0.000
N20.2 Calculus of kidney with calculus of ureter
0.766 0.234 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.766 0.234 0.000
F60 Specific personality disorders
0.764 0.236 0.000
B99-B99 Other infectious diseases
0.764 0.236 0.000
I83 Varicose veins of lower extremities
0.763 0.237 0.000
I49.9 Cardiac arrhythmia, unspecified
0.761 0.239 0.000
N21.1 Calculus in urethra
0.759 0.241 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.757 0.243 0.000
I25.2 Old myocardial infarction
0.754 0.246 0.000
I45.9 Conduction disorder, unspecified
0.751 0.249 0.000
A65-A69 Other spirochaetal diseases
0.749 0.251 0.000
H65-H75 Diseases of middle ear and mastoid
0.747 0.253 0.000
E27.8 Other specified disorders of adrenal gland
0.745 0.255 0.000
N46 Male infertility
0.745 0.255 0.000
I72.3 Aneurysm of iliac artery
0.743 0.257 0.000
F80-F89 Disorders of psychological development
0.742 0.258 0.000
F11 Mental and behavioural disorders due to use of opioids
0.741 0.259 0.000
F30-F39 Mood [affective] disorders
0.739 0.261 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.738 0.262 0.000
N21.8 Other lower urinary tract calculus
0.737 0.262 0.000
F10.1 Harmful use
0.736 0.264 0.000
Q76 Congenital malformations of spine and bony thorax
0.734 0.266 0.000
E13 Other specified diabetes mellitus
0.733 0.266 0.000
F70-F79 Mental retardation
0.733 0.267 0.000
F99-F99 Unspecified mental disorder
0.730 0.270 0.000
I36 Nonrheumatic tricuspid valve disorders
0.728 0.272 0.000
Q00-Q07 Congenital malformations of the nervous system
0.727 0.273 0.000
H92.1 Otorrhoea
0.726 0.274 0.000
I35.9 Aortic valve disorder, unspecified
0.725 0.275 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.723 0.277 0.000
I11 Hypertensive heart disease
0.723 0.277 0.000
E27.2 Addisonian crisis
0.722 0.278 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.720 0.280 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.720 0.280 0.000
A40.8 Other streptococcal septicaemia
0.720 0.280 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F17.2 Dependence syndrome
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E31 Polyglandular dysfunction
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.716 0.284 0.000
N44 Torsion of testis
0.716 0.284 0.000
L91 Hypertrophic disorders of skin
0.716 0.284 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.715 0.284 0.000
E21.4 Other specified disorders of parathyroid gland
0.715 0.284 0.000
E21.2 Other hyperparathyroidism
0.715 0.284 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.715 0.284 0.000
I45.2 Bifascicular block
0.715 0.285 0.000
I77.2 Rupture of artery
0.714 0.286 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.714 0.286 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.714 0.286 0.000
H93 Other disorders of ear, not elsewhere classified
0.713 0.287 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.713 0.287 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.712 0.288 0.000
N03.9 Unspecified
0.711 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
E70-E90 Metabolic disorders
0.709 0.291 0.000
N13.6 Pyonephrosis
0.709 0.291 0.000
B25-B34 Other viral diseases
0.708 0.292 0.000
A49.0 Staphylococcal infection, unspecified
0.707 0.293 0.000
N43 Hydrocele and spermatocele
0.707 0.293 0.000
E10.5 With peripheral circulatory complications
0.707 0.293 0.000
E12 Malnutrition-related diabetes mellitus
0.706 0.294 0.000
I45.4 Nonspecific intraventricular block
0.705 0.295 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.704 0.296 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.704 0.296 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.704 0.296 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.704 0.296 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.704 0.296 0.000
I24 Other acute ischaemic heart diseases
0.704 0.296 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.703 0.297 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.703 0.297 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.702 0.298 0.000
E23 Hypofunction and other disorders of pituitary gland
0.702 0.298 0.000
N99-N99 Other disorders of the genitourinary system
0.702 0.298 0.000
N86 Erosion and ectropion of cervix uteri
0.700 0.300 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.700 0.300 0.000
L89 Decubitus ulcer
0.699 0.301 0.000
N80 Endometriosis
0.699 0.301 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.699 0.301 0.000
E14.8 With unspecified complications
0.698 0.302 0.000
E14.7 With multiple complications
0.698 0.302 0.000
E14.6 With other specified complications
0.698 0.302 0.000
E14.5 With peripheral circulatory complications
0.698 0.302 0.000
E14.2 Withrenal complications
0.698 0.302 0.000
E14.1 With ketoacidosis
0.698 0.302 0.000
E14.0 With coma
0.698 0.302 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.697 0.303 0.000
A48 Other bacterial diseases, not elsewhere classified
0.697 0.303 0.000
E20 Hypoparathyroidism
0.696 0.303 0.000
E24.9 Cushing's syndrome, unspecified
0.697 0.303 0.000
E83 Disorders of mineral metabolism
0.696 0.304 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.696 0.304 0.000
E10.8 With unspecified complications
0.695 0.304 0.000
E27.1 Primary adrenocortical insufficiency
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.695 0.305 0.000
E10.4 With neurological complications
0.692 0.308 0.000
N41.8 Other inflammatory diseases of prostate
0.691 0.309 0.000
N41.3 Prostatocystitis
0.691 0.309 0.000
N41.2 Abscess of prostate
0.691 0.309 0.000
I38 Endocarditis, valve unspecified
0.690 0.310 0.000
A31 Infection due to other mycobacteria
0.689 0.311 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.688 0.312 0.000
I13 Hypertensive heart and renal disease
0.688 0.312 0.000
E28.3 Primary ovarian failure
0.686 0.314 0.000
I44 Atrioventricular and left bundle-branch block
0.684 0.316 0.000
N42.9 Disorder of prostate, unspecified
0.683 0.317 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.682 0.318 0.000
B50-B64 Protozoal diseases
0.682 0.318 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.681 0.318 0.000
N80.0 Endometriosis of uterus
0.681 0.319 0.000
E29 Testicular dysfunction
0.680 0.319 0.000
N05 Unspecified nephritic syndrome
0.680 0.320 0.000
F60.9 Personality disorder, unspecified
0.679 0.321 0.000
E10.3 With ophthalmic complications
0.678 0.322 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.678 0.322 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.678 0.322 0.000
E34 Other endocrine disorders
0.677 0.323 0.000
I78 Diseases of capillaries
0.675 0.325 0.000
E10.2 With renal complications
0.675 0.325 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.674 0.325 0.000
N15 Other renal tubulo-interstitial diseases
0.674 0.325 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.674 0.325 0.000
F10.9 Unspecified mental and behavioural disorder
0.674 0.326 0.000
L91.8 Other hypertrophic disorders of skin
0.673 0.327 0.000
L81 Other disorders of pigmentation
0.673 0.327 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.672 0.328 0.000
E83.4 Disorders of magnesium metabolism
0.672 0.328 0.000
Chapter VI Diseases of the nervous system
0.672 0.328 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.671 0.329 0.000
E27.9 Disorder of adrenal gland, unspecified
0.670 0.330 0.000
I77.5 Necrosis of artery
0.670 0.330 0.000
I77.4 Coeliac artery compression syndrome
0.670 0.330 0.000
I77.3 Arterial fibromuscular dysplasia
0.670 0.330 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.668 0.332 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.668 0.332 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.668 0.332 0.000
A75-A79 Rickettsioses
0.668 0.332 0.000
A70-A74 Other diseases caused by chlamydiae
0.668 0.332 0.000
A20-A28 Certain zoonotic bacterial diseases
0.668 0.332 0.000
A15-A19 Tuberculosis
0.668 0.332 0.000
I05-I09 Chronic rheumatic heart diseases
0.668 0.332 0.000
I49.2 Junctional premature depolarisation
0.667 0.332 0.000
I45.0 Right fascicular block
0.667 0.333 0.000
E83.1 Disorders of iron metabolism
0.667 0.333 0.000
E26.0 Primary hyperaldosteronism
0.666 0.334 0.000
I37 Pulmonary valve disorders
0.665 0.335 0.000
E27.5 Adrenomedullary hyperfunction
0.665 0.335 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.665 0.335 0.000
E27.0 Other adrenocortical overactivity
0.665 0.335 0.000
I45.3 Trifascicular block
0.665 0.335 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.662 0.338 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.662 0.338 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.661 0.338 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
A00-A09 Intestinal infectious diseases
0.659 0.341 0.000
L10-L14 Bullous disorders
0.659 0.341 0.000
I49.0 Ventricular fibrillation and flutter
0.658 0.342 0.000
F12.1 Harmful use
0.658 0.342 0.000
L71 Rosacea
0.658 0.342 0.000
F17.9 Unspecified mental and behavioural disorder
0.658 0.342 0.000
F17.8 Other mental and behavioural disorders
0.658 0.342 0.000
F17.7 Residual and late-onset psychotic disorder
0.658 0.342 0.000
F17.6 Amnesic syndrome
0.658 0.342 0.000
F17.5 Psychotic disorder
0.658 0.342 0.000
F17.4 Withdrawal state with delirium
0.658 0.342 0.000
F17.3 Withdrawal state
0.658 0.342 0.000
F17.0 Acute intoxication
0.658 0.342 0.000
E22 Hyperfunction of pituitary gland
0.656 0.344 0.000
I74.5 Embolism and thrombosis of iliac artery
0.653 0.347 0.000
I45.1 Other and unspecified right bundle-branch block
0.652 0.348 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.651 0.349 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.651 0.349 0.000
E10.1 With ketoacidosis
0.651 0.349 0.000
I77.0 Arteriovenous fistula, acquired
0.650 0.349 0.000
F10.8 Other mental and behavioural disorders
0.650 0.350 0.000
F10.7 Residual and late-onset psychotic disorder
0.650 0.350 0.000
F10.6 Amnesic syndrome
0.650 0.350 0.000
F10.5 Psychotic disorder
0.650 0.350 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.649 0.351 0.000
I88 Nonspecific lymphadenitis
0.647 0.353 0.000
I24.8 Other forms of acute ischaemic heart disease
0.647 0.353 0.000
I72.8 Aneurysm of other specified arteries
0.646 0.354 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.645 0.354 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.645 0.354 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.645 0.355 0.000
E14.3 With ophthalmic complications
0.645 0.355 0.000
A44 Bartonellosis
0.645 0.355 0.000
A43 Nocardiosis
0.645 0.355 0.000
A42 Actinomycosis
0.645 0.355 0.000
A39 Meningococcal infection
0.645 0.355 0.000
A37 Whooping cough
0.645 0.355 0.000
A36 Diphtheria
0.645 0.355 0.000
A32 Listeriosis
0.645 0.355 0.000
A30 Leprosy [Hansen's disease]
0.645 0.355 0.000
A38 Scarlet fever
0.645 0.355 0.000
A35 Other tetanus
0.645 0.355 0.000
A34 Obstetrical tetanus
0.645 0.355 0.000
A33 Tetanus neonatorum
0.645 0.355 0.000
B99 Other and unspecified infectious diseases
0.644 0.356 0.000
I42 Cardiomyopathy
0.641 0.359 0.000
I71.0 Dissection of aorta [any part]
0.641 0.359 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.640 0.360 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.640 0.360 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.640 0.360 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.640 0.360 0.000
E10.7 With multiple complications
0.640 0.360 0.000
E10.6 With other specified complications
0.640 0.360 0.000
Q35-Q37 Cleft lip and cleft palate
0.640 0.360 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.640 0.360 0.000
I23 Certain current complications following acute myocardial infarction
0.640 0.360 0.000
F19.1 Harmful use
0.635 0.365 0.000
E24.2 Drug-induced Cushing's syndrome
0.634 0.365 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.633 0.367 0.000
Q50-Q56 Congenital malformations of genital organs
0.633 0.367 0.000
I33 Acute and subacute endocarditis
0.632 0.367 0.000
Q80-Q89 Other congenital malformations
0.632 0.368 0.000
F12.2 Dependence syndrome
0.631 0.369 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.630 0.369 0.000
I45.8 Other specified conduction disorders
0.630 0.370 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.629 0.371 0.000
Q66 Congenital deformities of feet
0.628 0.372 0.000
H60-H62 Diseases of external ear
0.627 0.373 0.000
I35.1 Aortic (valve) insufficiency
0.626 0.374 0.000
F69 Unspecified disorder of adult personality and behaviour
0.626 0.374 0.000
B15-B19 Viral hepatitis
0.624 0.376 0.000
N42.1 Congestion and haemorrhage of prostate
0.623 0.376 0.000
H74 Other disorders of middle ear and mastoid
0.623 0.377 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.622 0.378 0.000
I72.4 Aneurysm of artery of lower extremity
0.621 0.378 0.000
N80.8 Other endometriosis
0.620 0.380 0.000
I47.1 Supraventricular tachycardia
0.620 0.380 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.619 0.381 0.000
N06 Isolated proteinuria with specified morphological lesion
0.619 0.381 0.000
N01 Rapidly progressive nephritic syndrome
0.619 0.381 0.000
N00 Acute nephritic syndrome
0.619 0.381 0.000
Q78 Other osteochondrodysplasias
0.618 0.381 0.000
A69 Other spirochaetal infections
0.618 0.382 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.616 0.383 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.616 0.383 0.000
F68 Other disorders of adult personality and behaviour
0.616 0.384 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.616 0.384 0.000
F65 Disorders of sexual preference
0.616 0.384 0.000
F63 Habit and impulse disorders
0.616 0.384 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.616 0.384 0.000
F61 Mixed and other personality disorders
0.616 0.384 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.616 0.384 0.000
N42.8 Other specified disorders of prostate
0.616 0.384 0.000
I30.9 Acute pericarditis, unspecified
0.614 0.386 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.614 0.386 0.000
H71 Cholesteatoma of middle ear
0.613 0.387 0.000
I72.9 Aneurysm of unspecified site
0.611 0.388 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.611 0.388 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.611 0.388 0.000
I72.2 Aneurysm of renal artery
0.611 0.388 0.000
I72.1 Aneurysm of artery of upper extremity
0.611 0.388 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.611 0.389 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.611 0.389 0.000
F33 Recurrent depressive disorder
0.610 0.390 0.000
Q65 Congenital deformities of hip
0.610 0.390 0.000
N25-N29 Other disorders of kidney and ureter
0.609 0.390 0.000
I51.8 Other ill-defined heart diseases
0.609 0.391 0.000
B65-B83 Helminthiases
0.608 0.391 0.000
A49.9 Bacterial infection, unspecified
0.608 0.392 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.608 0.392 0.000
F10.2 Dependence syndrome
0.607 0.393 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.605 0.395 0.000
I20 Angina pectoris
0.605 0.395 0.000
Q76.0 Spina bifida occulta
0.604 0.395 0.000
I44.7 Left bundle-branch block, unspecified
0.604 0.396 0.000
I70.0 Atherosclerosis of aorta
0.604 0.396 0.000
N80.9 Endometriosis, unspecified
0.604 0.396 0.000
F64 Gender identity disorders
0.603 0.396 0.000
I51.9 Heart disease, unspecified
0.603 0.397 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.602 0.398 0.000
Q43 Other congenital malformations of intestine
0.601 0.399 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.601 0.399 0.000
Q18 Other congenital malformations of face and neck
0.600 0.400 0.000
I25.6 Silent myocardial ischaemia
0.600 0.400 0.000
I25.4 Coronary artery aneurysm
0.600 0.400 0.000
L81.9 Disorder of pigmentation, unspecified
0.600 0.400 0.000
E24.8 Other Cushing's syndrome
0.599 0.401 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.599 0.401 0.000
E24.3 Ectopic ACTH syndrome
0.599 0.401 0.000
E24.1 Nelson's syndrome
0.599 0.401 0.000
E24.0 Pituitary-dependent Cushing's disease
0.599 0.401 0.000
A40.9 Streptococcal septicaemia, unspecified
0.598 0.402 0.000
E16 Other disorders of pancreatic internal secretion
0.598 0.402 0.000
A80-A89 Viral infections of the central nervous system
0.597 0.403 0.000
N42.2 Atrophy of prostate
0.597 0.403 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.595 0.405 0.000
I22 Subsequent myocardial infarction
0.594 0.405 0.000
F32 Depressive episode
0.593 0.407 0.000
I70.1 Atherosclerosis of renal artery
0.593 0.407 0.000
Q07 Other congenital malformations of nervous system
0.592 0.408 0.000
F60.3 Emotionally unstable personality disorder
0.592 0.408 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.592 0.408 0.000
A49.1 Streptococcal infection, unspecified
0.592 0.408 0.000
N91 Absent, scanty and rare menstruation
0.591 0.409 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.591 0.409 0.000
Q75 Other congenital malformations of skull and face bones
0.591 0.409 0.000
Q74 Other congenital malformations of limb(s)
0.591 0.409 0.000
Q73 Reduction defects of unspecified limb
0.591 0.409 0.000
Q72 Reduction defects of lower limb
0.591 0.409 0.000
Q71 Reduction defects of upper limb
0.591 0.409 0.000
Q70 Syndactyly
0.591 0.409 0.000
Q69 Polydactyly
0.591 0.409 0.000
Q68 Other congenital musculoskeletal deformities
0.591 0.409 0.000
E25.9 Adrenogenital disorder, unspecified
0.591 0.409 0.000
E25.8 Other adrenogenital disorders
0.591 0.409 0.000
I51.6 Cardiovascular disease, unspecified
0.590 0.410 0.000
A60.0 Herpesviral infection of genitalia and urogenital tract
0.590 0.410 0.000
N13.8 Other obstructive and reflux uropathy
0.589 0.410 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.589 0.411 0.000
Q04 Other congenital malformations of brain
0.589 0.411 0.000
L89.1 Stage II decubitus ulcer
0.588 0.412 0.000
I21 Acute myocardial infarction
0.587 0.413 0.000
L75 Apocrine sweat disorders
0.587 0.413 0.000
L74 Eccrine sweat disorders
0.587 0.413 0.000
L70 Acne
0.587 0.413 0.000
L68 Hypertrichosis
0.587 0.413 0.000
L67 Hair colour and hair shaft abnormalities
0.587 0.413 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.587 0.413 0.000
L64 Androgenic alopecia
0.587 0.413 0.000
L63 Alopecia areata
0.587 0.413 0.000
L62 Nail disorders in diseases classified elsewhere
0.587 0.413 0.000
I72.0 Aneurysm of carotid artery
0.585 0.414 0.000
I73 Other peripheral vascular diseases
0.585 0.415 0.000
N42.3 Dysplasia of prostate
0.585 0.415 0.000
H91 Other hearing loss
0.585 0.415 0.000
I77.8 Other specified disorders of arteries and arterioles
0.584 0.416 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.584 0.416 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.583 0.417 0.000
L87 Transepidermal elimination disorders
0.583 0.417 0.000
L88 Pyoderma gangrenosum
0.583 0.417 0.000
L86 Keratoderma in diseases classified elsewhere
0.583 0.417 0.000
F12.9 Unspecified mental and behavioural disorder
0.582 0.417 0.000
F12.8 Other mental and behavioural disorders
0.582 0.417 0.000
F12.7 Residual and late-onset psychotic disorder
0.582 0.417 0.000
F12.6 Amnesic syndrome
0.582 0.417 0.000
F12.5 Psychotic disorder
0.582 0.417 0.000
F12.4 Withdrawal state with delirium
0.582 0.417 0.000
F12.3 Withdrawal state
0.582 0.417 0.000
F12.0 Acute intoxication
0.582 0.417 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.582 0.418 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.581 0.419 0.000
F84 Pervasive developmental disorders
0.581 0.419 0.000
A40.2 Septicaemia due to streptococcus, group D
0.580 0.419 0.000
A40.1 Septicaemia due to streptococcus, group B
0.580 0.419 0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.579 0.420 0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.579 0.420 0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.579 0.420 0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.579 0.420 0.000
E26.9 Hyperaldosteronism, unspecified
0.577 0.422 0.000
E26.8 Other hyperaldosteronism
0.577 0.422 0.000
E26.1 Secondary hyperaldosteronism
0.577 0.422 0.000
I81 Portal vein thrombosis
0.577 0.423 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.577 0.423 0.000
L72.2 Steatocystoma multiplex
0.577 0.423 0.000
N20.9 Urinary calculus, unspecified
0.576 0.424 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.575 0.425 0.000
N80.2 Endometriosis of Fallopian tube
0.575 0.425 0.000
I47.0 Reentry ventricular arrhythmia
0.575 0.425 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.574 0.426 0.000
H90.0 Conductive hearing loss, bilateral
0.573 0.427 0.000
F39 Unspecified mood [affective] disorder
0.573 0.427 0.000
I86 Varicose veins of other sites
0.573 0.427 0.000
A49.3 Mycoplasma infection, unspecified
0.573 0.427 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.573 0.427 0.000
H92.2 Otorrhagia
0.572 0.428 0.000
I25.5 Ischaemic cardiomyopathy
0.572 0.428 0.000
L94 Other localised connective tissue disorders
0.572 0.428 0.000
I70.9 Generalised and unspecified atherosclerosis
0.571 0.429 0.000
I70.8 Atherosclerosis of other arteries
0.571 0.429 0.000
H92.0 Otalgia
0.571 0.429 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.570 0.430 0.000
I30.1 Infective pericarditis
0.570 0.430 0.000
F11.2 Dependence syndrome
0.569 0.431 0.000
L95.9 Vasculitis limited to skin, unspecified
0.569 0.431 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.569 0.431 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.568 0.432 0.000
H69 Other disorders of Eustachian tube
0.568 0.432 0.000
A49.8 Other bacterial infections of unspecified site
0.568 0.432 0.000
F45 Somatoform disorders
0.566 0.434 0.000
L65 Other nonscarring hair loss
0.565 0.435 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.565 0.435 0.000
G57 Mononeuropathies of lower limb
0.565 0.435 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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