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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28383172
log Bayes Factor = 102.266
Chromosome 6   position 32,565,979  (GRCh37) Explore rs28383172 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.003 0.997
G35 Multiple sclerosis
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.010 0.990
J20-J22 Other acute lower respiratory infections
0.000 0.010 0.990
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.011 0.989
L20-L30 Dermatitis and eczema
0.000 0.011 0.989
M34 Systemic sclerosis
0.000 0.012 0.988
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.013 0.987
J22 Unspecified acute lower respiratory infection
0.000 0.020 0.980
H02 Other disorders of eyelid
0.000 0.020 0.980
H04 Disorders of lachrymal system
0.000 0.021 0.979
N48 Other disorders of penis
0.976 0.024 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.024 0.976
N48.6 Balanitis xerotica obliterans
0.971 0.029 0.000
E10.4 With neurological complications
0.000 0.033 0.967
H55-H59 Other disorders of eye and adnexa
0.000 0.034 0.966
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.036 0.964
D68 Other coagulation defects
0.000 0.036 0.964
D50-D53 Nutritional anaemias
0.000 0.038 0.962
J80 Adult respiratory distress syndrome
0.000 0.038 0.962
J44 Other chronic obstructive pulmonary disease
0.000 0.039 0.961
H02.1 Ectropion of eyelid
0.000 0.040 0.960
H02.0 Entropion and trichiasis of eyelid
0.000 0.041 0.959
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.041 0.959
L40.0 Psoriasis vulgaris
0.958 0.042 0.000
J84 Other interstitial pulmonary diseases
0.000 0.042 0.958
E27 Other disorders of adrenal gland
0.000 0.048 0.952
M34.9 Systemic sclerosis, unspecified
0.000 0.049 0.951
D69 Purpura and other haemorrhagic conditions
0.000 0.052 0.948
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.055 0.945
J32 Chronic sinusitis
0.000 0.055 0.945
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.056 0.944
L30 Other dermatitis
0.000 0.056 0.944
E10.5 With peripheral circulatory complications
0.000 0.061 0.939
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.061 0.939
H57 Other disorders of eye and adnexa
0.000 0.062 0.938
E27.1 Primary adrenocortical insufficiency
0.000 0.064 0.936
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.064 0.936
E06 Thyroiditis
0.000 0.066 0.934
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.067 0.933
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.069 0.931
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.070 0.930
M06.0 Seronegative rheumatoid arthritis
0.000 0.070 0.930
E10.2 With renal complications
0.000 0.077 0.923
N48.0 Leukoplakia of penis
0.919 0.081 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.082 0.918
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.083 0.917
D50 Iron deficiency anaemia
0.000 0.084 0.916
N48.8 Other specified disorders of penis
0.915 0.085 0.000
L81 Other disorders of pigmentation
0.000 0.093 0.906
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.094 0.906
L85 Other epidermal thickening
0.000 0.101 0.899
J95-J99 Other diseases of the respiratory system
0.000 0.104 0.896
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.104 0.896
L29 Pruritus
0.000 0.106 0.894
J33.8 Other polyp of sinus
0.000 0.107 0.893
Chapter VI Diseases of the nervous system
0.000 0.107 0.893
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.108 0.892
D50.8 Other iron deficiency anaemias
0.000 0.112 0.888
H57.0 Anomalies of pupillary function
0.000 0.113 0.887
L30.9 Dermatitis, unspecified
0.000 0.115 0.885
E07 Other disorders of thyroid
0.000 0.116 0.884
D68.9 Coagulation defect, unspecified
0.000 0.118 0.882
E06.3 Autoimmune thyroiditis
0.000 0.118 0.882
M35.1 Other overlap syndromes
0.000 0.120 0.880
H06.2 Dysthyroid exophthalmos
0.000 0.120 0.880
D68.8 Other specified coagulation defects
0.000 0.121 0.879
N48.9 Disorder of penis, unspecified
0.876 0.124 0.000
M34.1 CR(E)ST syndrome
0.000 0.125 0.875
N48.4 Impotence of organic origin
0.875 0.125 0.000
J31.0 Chronic rhinitis
0.000 0.126 0.874
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.127 0.873
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.131 0.869
L81.4 Other melanin hyperpigmentation
0.000 0.132 0.868
M06.3 Rheumatoid nodule
0.000 0.132 0.868
N48.1 Balanoposthitis
0.868 0.132 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.137 0.863
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.142 0.858
M06.4 Inflammatory polyarthropathy
0.000 0.142 0.858
J81 Pulmonary oedema
0.000 0.142 0.858
L85.9 Epidermal thickening, unspecified
0.000 0.151 0.849
N40-N51 Diseases of male genital organs
0.848 0.152 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.155 0.845
J32.0 Chronic maxillary sinusitis
0.000 0.155 0.845
N47 Redundant prepuce, phimosis and paraphimosis
0.844 0.156 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.157 0.843
D68.5 Primary Thrombophilia
0.000 0.158 0.842
E28 Ovarian dysfunction
0.000 0.160 0.840
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.163 0.837
L29.0 Pruritus ani
0.000 0.164 0.836
L30.8 Other specified dermatitis
0.000 0.168 0.832
M34.8 Other forms of systemic sclerosis
0.000 0.168 0.832
L83 Acanthosis nigricans
0.000 0.169 0.831
D52 Folate deficiency anaemia
0.000 0.174 0.826
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.174 0.826
L21 Seborrhoeic dermatitis
0.000 0.174 0.826
L93 Lupus erythematosus
0.000 0.175 0.825
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.175 0.825
H05 Disorders of orbit
0.000 0.175 0.825
L94 Other localised connective tissue disorders
0.000 0.179 0.821
M32 Systemic lupus erythematosus
0.000 0.180 0.820
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.181 0.819
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.183 0.817
H04.8 Other disorders of lachrymal system
0.000 0.185 0.815
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.188 0.812
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.188 0.812
H16 Keratitis
0.000 0.190 0.810
J32.9 Chronic sinusitis, unspecified
0.000 0.192 0.808
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.192 0.808
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.192 0.808
L57.0 Actinic keratosis
0.000 0.193 0.807
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.193 0.807
E04 Other non-toxic goitre
0.000 0.194 0.806
E29 Testicular dysfunction
0.000 0.199 0.801
J32.8 Other chronic sinusitis
0.000 0.200 0.800
D60-D64 Aplastic and other anaemias
0.000 0.201 0.799
E10.8 With unspecified complications
0.000 0.202 0.798
D69.5 Secondary thrombocytopenia
0.000 0.203 0.797
H55 Nystagmus and other irregular eye movements
0.000 0.204 0.796
H57.8 Other specified disorders of eye and adnexa
0.000 0.204 0.796
N48.5 Ulcer of penis
0.793 0.207 0.000
E20 Hypoparathyroidism
0.000 0.207 0.793
M06.34 Rheumatoid nodule (Hand)
0.000 0.214 0.786
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.215 0.785
E07.9 Disorder of thyroid, unspecified
0.000 0.216 0.784
D69.0 Allergic purpura
0.000 0.217 0.783
L40-L45 Papulosquamous disorders
0.505 0.217 0.278
H02.6 Xanthelasma of eyelid
0.000 0.220 0.780
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.224 0.776
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.226 0.774
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.230 0.770
J84.8 Other specified interstitial pulmonary diseases
0.000 0.230 0.770
E05.8 Other thyrotoxicosis
0.000 0.230 0.770
H57.9 Disorder of eye and adnexa, unspecified
0.000 0.233 0.767
G37 Other demyelinating diseases of central nervous system
0.000 0.240 0.760
E27.8 Other specified disorders of adrenal gland
0.000 0.241 0.759
H20 Iridocyclitis
0.000 0.242 0.758
H16.0 Corneal ulcer
0.000 0.244 0.756
M35.7 Hypermobility syndrome
0.000 0.244 0.756
D68.0 Von Willebrand's disease
0.000 0.245 0.755
L40.1 Generalised pustular psoriasis
0.752 0.248 0.000
H04.1 Other disorders of lachrymal gland
0.000 0.249 0.751
L27 Dermatitis due to substances taken internally
0.000 0.249 0.751
J21 Acute bronchiolitis
0.000 0.249 0.751
E04.2 Non-toxic multinodular goitre
0.000 0.250 0.750
L80 Vitiligo
0.000 0.251 0.749
J20 Acute bronchitis
0.000 0.251 0.749
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.255 0.745
L20 Atopic dermatitis
0.000 0.259 0.741
H01 Other inflammation of eyelid
0.000 0.259 0.741
L25 Unspecified contact dermatitis
0.000 0.259 0.741
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.262 0.738
D61 Other aplastic anaemias
0.000 0.263 0.737
J95.8 Other postprocedural respiratory disorders
0.000 0.264 0.736
L28 Lichen simplex chronicus and prurigo
0.000 0.265 0.735
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.266 0.734
M22 Disorders of patella
0.000 0.267 0.733
N48.2 Other inflammatory disorders of penis
0.732 0.268 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.269 0.731
L29.2 Pruritus vulvae
0.000 0.270 0.730
H05.0 Acute inflammation of orbit
0.000 0.271 0.729
D52.9 Folate deficiency anaemia, unspecified
0.000 0.272 0.728
E14 Unspecified diabetes mellitus
0.000 0.273 0.727
E10.6 With other specified complications
0.000 0.274 0.726
H04.9 Disorder of lachrymal system, unspecified
0.000 0.277 0.723
M60-M63 Disorders of muscles
0.000 0.279 0.721
D80-D89 Certain disorders involving the immune mechanism
0.000 0.279 0.721
L84 Corns and callosities
0.000 0.280 0.720
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.281 0.719
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
N45 Orchitis and epididymitis
0.717 0.283 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
E26 Hyperaldosteronism
0.000 0.285 0.715
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.286 0.714
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.290 0.710
L87 Transepidermal elimination disorders
0.000 0.290 0.710
L88 Pyoderma gangrenosum
0.000 0.290 0.710
L86 Keratoderma in diseases classified elsewhere
0.000 0.290 0.710
D67 Hereditary factor IX deficiency
0.000 0.291 0.709
L24 Irritant contact dermatitis
0.000 0.291 0.709
L26 Exfoliative dermatitis
0.000 0.291 0.709
L22 Diaper [napkin] dermatitis
0.000 0.291 0.709
H04.4 Chronic inflammation of lachrymal passages
0.000 0.291 0.709
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.291 0.708
M34.0 Progressive systemic sclerosis
0.000 0.291 0.708
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.292 0.708
L93.0 Discoid lupus erythematosus
0.000 0.293 0.707
J31.2 Chronic pharyngitis
0.000 0.296 0.703
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.297 0.703
H04.6 Other changes in lachrymal passages
0.000 0.298 0.702
H04.0 Dacryoadenitis
0.000 0.298 0.702
M30 Polyarteritis nodosa and related conditions
0.000 0.299 0.701
N48.3 Priapism
0.700 0.300 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.300 0.700
E32 Diseases of thymus
0.000 0.300 0.700
E31 Polyglandular dysfunction
0.000 0.300 0.700
E30 Disorders of puberty, not elsewhere classified
0.000 0.300 0.700
D68.6 Other Thrombophilia
0.000 0.302 0.698
E06.9 Thyroiditis, unspecified
0.000 0.302 0.698
J32.1 Chronic frontal sinusitis
0.000 0.304 0.696
E28.2 Polycystic ovarian syndrome
0.000 0.304 0.696
E23.2 Diabetes insipidus
0.000 0.306 0.694
D51 Vitamin B12 deficiency anaemia
0.000 0.307 0.693
D61.9 Aplastic anaemia, unspecified
0.000 0.307 0.693
E03.8 Other specified hypothyroidism
0.000 0.308 0.692
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.309 0.691
D68.4 Acquired coagulation factor deficiency
0.000 0.309 0.691
H30 Chorioretinal inflammation
0.000 0.309 0.691
E27.9 Disorder of adrenal gland, unspecified
0.000 0.311 0.689
L82 Seborrhoeic keratosis
0.000 0.311 0.689
M12 Other specific arthropathies
0.000 0.312 0.688
L58 Radiodermatitis
0.000 0.312 0.687
L55 Sunburn
0.000 0.312 0.687
J95.0 Tracheostomy malfunction
0.000 0.313 0.687
J84.0 Alveolar and parietoalveolar conditions
0.000 0.313 0.687
L94.0 Localised scleroderma [morphea]
0.000 0.315 0.685
H02.2 Lagophthalmos
0.000 0.316 0.684
H02.5 Other disorders affecting eyelid function
0.000 0.316 0.684
D68.1 Hereditary factor XI deficiency
0.000 0.317 0.683
E27.5 Adrenomedullary hyperfunction
0.000 0.318 0.682
E27.0 Other adrenocortical overactivity
0.000 0.318 0.682
D69.8 Other specified haemorrhagic conditions
0.000 0.320 0.680
D69.4 Other primary thrombocytopenia
0.000 0.320 0.680
D69.1 Qualitative platelet defects
0.000 0.320 0.680
J32.4 Chronic pansinusitis
0.000 0.321 0.679
E28.3 Primary ovarian failure
0.000 0.321 0.678
E07.8 Other specified disorders of thyroid
0.000 0.322 0.678
G36 Other acute disseminated demyelination
0.000 0.322 0.678
H53-H54 Visual disturbances and blindness
0.000 0.322 0.678
J32.3 Chronic sphenoidal sinusitis
0.000 0.323 0.677
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.323 0.677
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.323 0.677
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.323 0.677
L98.1 Factitial dermatitis
0.000 0.323 0.677
L30.5 Pityriasis alba
0.000 0.323 0.677
L30.4 Erythema intertrigo
0.000 0.323 0.677
L30.2 Cutaneous autosensitisation
0.000 0.323 0.677
L30.1 Dyshidrosis [pompholyx]
0.000 0.323 0.677
L30.0 Nummular dermatitis
0.000 0.323 0.677
E29.1 Testicular hypofunction
0.000 0.324 0.676
L57.4 Cutis laxa senilis
0.000 0.325 0.675
E23.6 Other disorders of pituitary gland
0.000 0.328 0.672
D69.6 Thrombocytopenia, unspecified
0.000 0.329 0.671
E06.5 Other chronic thyroiditis
0.000 0.330 0.670
E06.4 Drug-induced thyroiditis
0.000 0.330 0.670
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.330 0.670
E06.1 Subacute thyroiditis
0.000 0.330 0.670
E06.0 Acute thyroiditis
0.000 0.330 0.670
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.331 0.669
L57.5 Actinic granuloma
0.000 0.331 0.669
L57.3 Poikiloderma of Civatte
0.000 0.331 0.669
L57.2 Cutis rhomboidalis nuchae
0.000 0.331 0.669
L57.1 Actinic reticuloid
0.000 0.331 0.669
H05.2 Exophthalmic conditions
0.000 0.331 0.669
E16 Other disorders of pancreatic internal secretion
0.000 0.332 0.668
J31.1 Chronic nasopharyngitis
0.000 0.332 0.668
J60-J70 Lung diseases due to external agents
0.000 0.333 0.667
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.333 0.667
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.333 0.667
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.333 0.667
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.333 0.667
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.333 0.667
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.333 0.667
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.333 0.667
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.333 0.667
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.333 0.667
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.333 0.667
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.333 0.667
D53 Other nutritional anaemias
0.000 0.334 0.666
L10-L14 Bullous disorders
0.000 0.335 0.664
M00-M03 Infectious arthropathies
0.000 0.336 0.664
N44 Torsion of testis
0.663 0.337 0.000
M86-M90 Other osteopathies
0.000 0.337 0.663
E20.9 Hypoparathyroidism, unspecified
0.000 0.338 0.662
L40.8 Other psoriasis
0.661 0.338 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.341 0.659
M22.2 Patellofemoral disorders
0.000 0.342 0.658
L95.8 Other vasculitis limited to skin
0.000 0.342 0.658
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.342 0.658
G90-G99 Other disorders of the nervous system
0.000 0.343 0.657
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.343 0.657
D50.1 Sideropenic dysphagia
0.000 0.343 0.656
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.346 0.654
J37 Chronic laryngitis and laryngotracheitis
0.000 0.347 0.653
E34 Other endocrine disorders
0.000 0.350 0.650
L81.7 Pigmented purpuric dermatosis
0.000 0.350 0.650
L81.6 Other disorders of diminished melanin formation
0.000 0.350 0.650
L81.5 Leukoderma, not elsewhere classified
0.000 0.350 0.650
L81.3 Cafe au lait spots
0.000 0.350 0.650
L81.2 Freckles
0.000 0.350 0.650
L81.1 Chloasma
0.000 0.350 0.650
L81.0 Postinflammatory hyperpigmentation
0.000 0.350 0.650
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.351 0.649
E27.2 Addisonian crisis
0.000 0.353 0.647
M31 Other necrotising vasculopathies
0.000 0.355 0.645
E22 Hyperfunction of pituitary gland
0.000 0.355 0.644
L85.3 Xerosis cutis
0.000 0.355 0.644
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.355 0.644
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.355 0.644
L85.0 Acquired ichthyosis
0.000 0.355 0.644
H20.8 Other iridocyclitis
0.000 0.356 0.644
E04.0 Non-toxic diffuse goitre
0.000 0.356 0.644
J96 Respiratory failure, not elsewhere classified
0.000 0.358 0.642
L95.9 Vasculitis limited to skin, unspecified
0.000 0.358 0.642
J35 Chronic diseases of tonsils and adenoids
0.000 0.358 0.641
L98.5 Mucinosis of skin
0.000 0.359 0.641
H16.9 Keratitis, unspecified
0.000 0.359 0.641
L29.1 Pruritus scroti
0.000 0.359 0.641
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.360 0.640
H57.1 Ocular pain
0.000 0.364 0.636
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.635 0.365 0.000
E07.1 Dyshormogenetic goitre
0.000 0.366 0.634
E07.0 Hypersecretion of calcitonin
0.000 0.366 0.634
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.367 0.633
L94.2 Calcinosis cutis
0.000 0.370 0.630
L81.8 Other specified disorders of pigmentation
0.000 0.371 0.629
L23 Allergic contact dermatitis
0.000 0.371 0.629
H01.8 Other specified inflammation of eyelid
0.000 0.372 0.628
J00-J06 Acute upper respiratory infections
0.000 0.372 0.628
G80 Infantile cerebral palsy
0.000 0.375 0.625
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.625 0.375 0.000
D86 Sarcoidosis
0.000 0.375 0.625
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.377 0.623
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.378 0.622
M06.38 Rheumatoid nodule (Other)
0.000 0.378 0.622
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.378 0.622
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.378 0.622
M06.33 Rheumatoid nodule (Forearm)
0.000 0.378 0.622
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.378 0.622
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.378 0.622
E23.7 Disorder of pituitary gland, unspecified
0.000 0.378 0.622
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.379 0.621
L29.9 Pruritus, unspecified
0.000 0.379 0.621
M45-M49 Spondylopathies
0.001 0.379 0.620
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.380 0.619
H00 Hordeolum and chalazion
0.000 0.381 0.619
H31 Other disorders of choroid
0.000 0.383 0.617
H02.4 Ptosis of eyelid
0.000 0.383 0.617
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.385 0.615
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.385 0.615
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.385 0.615
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.385 0.615
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.385 0.615
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.385 0.615
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.385 0.615
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.385 0.615
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.385 0.615
E23.0 Hypopituitarism
0.000 0.385 0.615
E14.3 With ophthalmic complications
0.000 0.389 0.611
M45 Ankylosing spondylitis
0.000 0.392 0.608
N42 Other disorders of prostate
0.608 0.392 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.608 0.392 0.000
D62 Acute posthaemorrhagic anaemia
0.000 0.392 0.608
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.393 0.607
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.393 0.607
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.394 0.606
M11 Other crystal arthropathies
0.000 0.394 0.605
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.395 0.605
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.395 0.604
E23.1 Drug-induced hypopituitarism
0.000 0.395 0.604
E16.2 Hypoglycaemia, unspecified
0.000 0.395 0.605
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.397 0.603
H15 Disorders of sclera
0.000 0.397 0.603
E28.9 Ovarian dysfunction, unspecified
0.000 0.398 0.602
E28.8 Other ovarian dysfunction
0.000 0.398 0.602
E28.1 Androgen excess
0.000 0.398 0.602
E28.0 Oestrogen excess
0.000 0.398 0.602
G80.9 Infantile cerebral palsy, unspecified
0.000 0.398 0.602
M21 Other acquired deformities of limbs
0.000 0.398 0.602
D55-D59 Haemolytic anaemias
0.000 0.398 0.601
G91 Hydrocephalus
0.000 0.399 0.601
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.401 0.599
E40-E46 Malnutrition
0.000 0.402 0.598
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.403 0.597
L29.8 Other pruritus
0.000 0.404 0.596
M33 Dermatopolymyositis
0.000 0.404 0.596
E25 Adrenogenital disorders
0.000 0.407 0.592
J20.9 Acute bronchitis, unspecified
0.000 0.407 0.592
D52.8 Other folate deficiency anaemias
0.000 0.408 0.592
D52.1 Drug-induced folate deficiency anaemia
0.000 0.408 0.592
D52.0 Dietary folate deficiency anaemia
0.000 0.408 0.592
L21.8 Other seborrhoeic dermatitis
0.000 0.408 0.592
L21.1 Seborrhoeic infantile dermatitis
0.000 0.408 0.592
L21.0 Seborrhoea capitis
0.000 0.408 0.592
L93.2 Other local lupus erythematosus
0.000 0.408 0.592
L93.1 Subacute cutaneous lupus erythematosus
0.000 0.408 0.592
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.409 0.591
H05.3 Deformity of orbit
0.000 0.409 0.591
E65-E68 Obesity and other hyperalimentation
0.000 0.409 0.591
L94.8 Other specified localised connective tissue disorders
0.000 0.411 0.589
L94.6 Ainhum
0.000 0.411 0.589
L94.5 Poikiloderma vasculare atrophicans
0.000 0.411 0.589
L94.4 Gottron's papules
0.000 0.411 0.589
L94.3 Sclerodactyly
0.000 0.411 0.589
L94.1 Linear scleroderma
0.000 0.411 0.589
L30.3 Infective dermatitis
0.000 0.412 0.588
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.412 0.588
M32.8 Other forms of systemic lupus erythematosus
0.000 0.412 0.588
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.412 0.588
L95.1 Erythema elevatum diutinum
0.000 0.413 0.587
L95.0 Livedoid vasculitis
0.000 0.413 0.587
M14 Arthropathies in other diseases classified elsewhere
0.000 0.414 0.586
H20.9 Iridocyclitis, unspecified
0.000 0.416 0.584
J35.0 Chronic tonsillitis
0.000 0.416 0.583
H05.8 Other disorders of orbit
0.000 0.417 0.583
L44 Other papulosquamous disorders
0.409 0.417 0.174
J95.5 Postprocedural subglottic stenosis
0.000 0.418 0.582
J95.4 Mendelson's syndrome
0.000 0.418 0.582
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.418 0.582

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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