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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844647
log Bayes Factor = 93.3345
Chromosome 6   position 31,011,013  (GRCh37) Explore rs2844647 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.999 0.001 0.000
E10.9 Without complications
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E20-E35 Disorders of other endocrine glands
0.997 0.003 0.000
E24 Cushing's syndrome
0.985 0.015 0.000
E23 Hypofunction and other disorders of pituitary gland
0.968 0.032 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.944 0.056 0.000
E24.9 Cushing's syndrome, unspecified
0.935 0.065 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.909 0.091 0.000
E03.8 Other specified hypothyroidism
0.896 0.104 0.000
E14 Unspecified diabetes mellitus
0.889 0.111 0.000
E28 Ovarian dysfunction
0.887 0.113 0.000
E23.6 Other disorders of pituitary gland
0.885 0.115 0.000
E21.3 Hyperparathyroidism, unspecified
0.875 0.125 0.000
E23.2 Diabetes insipidus
0.873 0.127 0.000
E24.0 Pituitary-dependent Cushing's disease
0.871 0.128 0.000
K90 Intestinal malabsorption
0.870 0.130 0.000
E24.2 Drug-induced Cushing's syndrome
0.852 0.148 0.000
E10.0 With coma
0.838 0.161 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.822 0.178 0.000
E14.3 With ophthalmic complications
0.819 0.181 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.810 0.189 0.000
K90.9 Intestinal malabsorption, unspecified
0.798 0.202 0.000
E28.2 Polycystic ovarian syndrome
0.797 0.203 0.000
E10.1 With ketoacidosis
0.794 0.206 0.000
E23.7 Disorder of pituitary gland, unspecified
0.794 0.206 0.000
L40 Psoriasis
0.786 0.214 0.000
E10.2 With renal complications
0.782 0.218 0.000
E10.6 With other specified complications
0.777 0.223 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.773 0.227 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.768 0.232 0.000
E31 Polyglandular dysfunction
0.756 0.243 0.000
E07 Other disorders of thyroid
0.753 0.247 0.000
E24.8 Other Cushing's syndrome
0.739 0.261 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.733 0.267 0.000
E20 Hypoparathyroidism
0.730 0.270 0.000
L40.5 Arthropathic psoriasis
0.729 0.271 0.000
E40-E46 Malnutrition
0.727 0.273 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.718 0.282 0.000
E10.8 With unspecified complications
0.718 0.282 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.715 0.285 0.000
E32 Diseases of thymus
0.715 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.715 0.285 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
E14.1 With ketoacidosis
0.709 0.291 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.706 0.293 0.000
E24.3 Ectopic ACTH syndrome
0.706 0.293 0.000
E24.1 Nelson's syndrome
0.706 0.293 0.000
K90.8 Other intestinal malabsorption
0.699 0.301 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.694 0.306 0.000
E23.1 Drug-induced hypopituitarism
0.694 0.306 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.683 0.317 0.000
E10.7 With multiple complications
0.683 0.317 0.000
E10.4 With neurological complications
0.676 0.324 0.000
E16 Other disorders of pancreatic internal secretion
0.675 0.325 0.000
E28.3 Primary ovarian failure
0.664 0.336 0.000
E14.4 With neurological complications
0.663 0.337 0.000
E14.6 With other specified complications
0.661 0.339 0.000
E14.0 With coma
0.661 0.339 0.000
E23.0 Hypopituitarism
0.658 0.342 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.648 0.352 0.000
L40.1 Generalised pustular psoriasis
0.644 0.356 0.000
E14.5 With peripheral circulatory complications
0.644 0.356 0.000
E14.8 With unspecified complications
0.641 0.359 0.000
E14.7 With multiple complications
0.637 0.363 0.000
E28.9 Ovarian dysfunction, unspecified
0.636 0.364 0.000
E28.8 Other ovarian dysfunction
0.636 0.364 0.000
E28.1 Androgen excess
0.636 0.364 0.000
E28.0 Oestrogen excess
0.636 0.364 0.000
E10.5 With peripheral circulatory complications
0.630 0.370 0.000
M45 Ankylosing spondylitis
0.000 0.372 0.628
E25 Adrenogenital disorders
0.625 0.374 0.000
K90.3 Pancreatic steatorrhoea
0.624 0.376 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.624 0.376 0.000
K90.1 Tropical sprue
0.624 0.376 0.000
E27 Other disorders of adrenal gland
0.617 0.383 0.000
E14.2 Withrenal complications
0.614 0.386 0.000
E07.8 Other specified disorders of thyroid
0.607 0.393 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.606 0.394 0.000
E03.1 Congenital hypothyroidism without goitre
0.605 0.395 0.000
E29 Testicular dysfunction
0.600 0.400 0.000
E21.2 Other hyperparathyroidism
0.598 0.402 0.000
L40.0 Psoriasis vulgaris
0.596 0.404 0.000
E31.0 Autoimmune polyglandular failure
0.584 0.416 0.000
E15 Nondiabetic hypoglycaemic coma
0.581 0.419 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.420 0.580
E05.8 Other thyrotoxicosis
0.576 0.424 0.000
E21.4 Other specified disorders of parathyroid gland
0.573 0.426 0.000
E22 Hyperfunction of pituitary gland
0.569 0.430 0.000
E26 Hyperaldosteronism
0.564 0.436 0.000
L40.2 Acrodermatitis continua
0.563 0.436 0.000
E20.1 Pseudohypoparathyroidism
0.563 0.437 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.558 0.442 0.000
E13.3 With ophthalmic complications
0.554 0.446 0.000
E31.9 Polyglandular dysfunction, unspecified
0.542 0.457 0.000
E31.8 Other polyglandular dysfunction
0.542 0.457 0.000
E31.1 Polyglandular hyperfunction
0.542 0.457 0.000
E07.1 Dyshormogenetic goitre
0.540 0.460 0.000
E07.0 Hypersecretion of calcitonin
0.540 0.460 0.000
L40.8 Other psoriasis
0.535 0.465 0.000
E46 Unspecified protein-energy malnutrition
0.531 0.469 0.000
E20.8 Other hypoparathyroidism
0.523 0.476 0.000
E20.0 Idiopathic hypoparathyroidism
0.523 0.476 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.521 0.479 0.000
E45 Retarded development following protein-energy malnutrition
0.521 0.479 0.000
E43 Unspecified severe protein-energy malnutrition
0.521 0.479 0.000
E42 Marasmic kwashiorkor
0.521 0.479 0.000
E41 Nutritional marasmus
0.521 0.479 0.000
E40 Kwashiorkor
0.521 0.479 0.000
E27.9 Disorder of adrenal gland, unspecified
0.518 0.482 0.000
L40.3 Pustulosis palmaris et plantaris
0.517 0.483 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.513 0.487 0.000
E30.8 Other disorders of puberty
0.513 0.487 0.000
E30.1 Precocious puberty
0.513 0.487 0.000
E30.0 Delayed puberty
0.513 0.487 0.000
E32.9 Disease of thymus, unspecified
0.513 0.487 0.000
E32.8 Other diseases of thymus
0.513 0.487 0.000
E32.1 Abscess of thymus
0.513 0.487 0.000
E32.0 Persistent hyperplasia of thymus
0.513 0.487 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.513 0.487 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.513 0.487 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.513 0.487 0.000
E16.2 Hypoglycaemia, unspecified
0.510 0.490 0.000
E13.8 With unspecified complications
0.510 0.490 0.000
E13.7 With multiple complications
0.510 0.490 0.000
E13.6 With other specified complications
0.510 0.490 0.000
E13.5 With peripheral circulatory complications
0.510 0.490 0.000
E13.4 With neurological complications
0.510 0.490 0.000
E13.2 With renal complications
0.510 0.490 0.000
E13.1 With ketoacidosis
0.510 0.490 0.000
E13.0 With coma
0.510 0.490 0.000
R31 Unspecified haematuria
0.000 0.499 0.501
E20.9 Hypoparathyroidism, unspecified
0.494 0.506 0.000
E07.9 Disorder of thyroid, unspecified
0.493 0.507 0.000
E16.1 Other hypoglycaemia
0.490 0.510 0.000
D64.9 Anaemia, unspecified
0.486 0.514 0.000
E06 Thyroiditis
0.484 0.515 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.484 0.516 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.484 0.516 0.000
E16.4 Abnormal secretion of gastrin
0.484 0.516 0.000
E16.3 Increased secretion of glucagon
0.484 0.516 0.000
E27.1 Primary adrenocortical insufficiency
0.477 0.523 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.469 0.531 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.550 0.450
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.550 0.450
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.550 0.450
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.550 0.450
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.550 0.450
E25.9 Adrenogenital disorder, unspecified
0.448 0.551 0.000
E25.8 Other adrenogenital disorders
0.448 0.551 0.000
E13.9 Without complications
0.448 0.552 0.000
E27.5 Adrenomedullary hyperfunction
0.442 0.557 0.000
E27.0 Other adrenocortical overactivity
0.442 0.557 0.000
L40.4 Guttate psoriasis
0.441 0.558 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.563 0.437
E29.9 Testicular dysfunction, unspecified
0.430 0.569 0.000
E29.8 Other testicular dysfunction
0.430 0.569 0.000
E29.0 Testicular hyperfunction
0.430 0.569 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.574 0.426
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.580 0.420
E27.4 Other and unspecified adrenocortical insufficiency
0.417 0.583 0.000
C61 Malignant neoplasm of prostate
0.000 0.583 0.417
E22.9 Hyperfunction of pituitary gland, unspecified
0.408 0.592 0.000
E22.8 Other hyperfunction of pituitary gland
0.408 0.592 0.000
E27.2 Addisonian crisis
0.407 0.593 0.000
E26.8 Other hyperaldosteronism
0.404 0.595 0.000
E26.1 Secondary hyperaldosteronism
0.404 0.595 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.391 0.608 0.000
E26.9 Hyperaldosteronism, unspecified
0.375 0.625 0.000
E44.1 Mild protein-energy malnutrition
0.374 0.626 0.000
E44.0 Moderate protein-energy malnutrition
0.374 0.626 0.000
E14.9 Without complications
0.373 0.627 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.358 0.641 0.001
E06.5 Other chronic thyroiditis
0.348 0.651 0.000
E06.4 Drug-induced thyroiditis
0.347 0.652 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.347 0.652 0.000
E06.0 Acute thyroiditis
0.347 0.652 0.000
D64 Other anaemias
0.346 0.654 0.000
E22.1 Hyperprolactinaemia
0.332 0.668 0.000
E29.1 Testicular hypofunction
0.316 0.684 0.000
E06.3 Autoimmune thyroiditis
0.312 0.688 0.000
E26.0 Primary hyperaldosteronism
0.302 0.697 0.000
E34 Other endocrine disorders
0.292 0.706 0.002
E06.1 Subacute thyroiditis
0.289 0.711 0.000
E21.0 Primary hyperparathyroidism
0.281 0.719 0.000
E27.8 Other specified disorders of adrenal gland
0.279 0.721 0.000
E06.9 Thyroiditis, unspecified
0.277 0.723 0.000
L40-L45 Papulosquamous disorders
0.265 0.735 0.000
D64.4 Congenital dyserythropoietic anaemia
0.248 0.752 0.000
D64.3 Other sideroblastic anaemias
0.248 0.752 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.248 0.752 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.248 0.752 0.000
D64.0 Hereditary sideroblastic anaemia
0.248 0.752 0.000
D64.8 Other specified anaemias
0.247 0.753 0.000
D60-D64 Aplastic and other anaemias
0.246 0.754 0.000
E65-E68 Obesity and other hyperalimentation
0.223 0.760 0.017
E22.0 Acromegaly and pituitary gigantism
0.236 0.764 0.000
D61 Other aplastic anaemias
0.223 0.777 0.000
D62 Acute posthaemorrhagic anaemia
0.221 0.779 0.000
E50-E64 Other nutritional deficiencies
0.211 0.789 0.000
E34.5 Androgen resistance syndrome
0.209 0.789 0.001
E34.4 Constitutional tall stature
0.209 0.789 0.001
E34.3 Short stature, not elsewhere classified
0.209 0.789 0.001
E34.2 Ectopic hormone secretion, not elsewhere classified
0.209 0.789 0.001
E34.1 Other hypersecretion of intestinal hormones
0.209 0.789 0.001
L42 Pityriasis rosea
0.208 0.792 0.000
D61.9 Aplastic anaemia, unspecified
0.205 0.795 0.000
L44 Other papulosquamous disorders
0.195 0.804 0.000
L41 Parapsoriasis
0.190 0.809 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.190 0.809 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.181 0.819 0.000
E67 Other hyperalimentation
0.160 0.828 0.012
E68 Sequelae of hyperalimentation
0.160 0.828 0.012
D61.0 Constitutional aplastic anaemia
0.172 0.828 0.000
E34.8 Other specified endocrine disorders
0.168 0.831 0.001
E51 Thiamine deficiency
0.169 0.831 0.000
E63 Other nutritional deficiencies
0.160 0.840 0.000
D61.8 Other specified aplastic anaemias
0.160 0.840 0.000
D61.3 Idiopathic aplastic anaemia
0.160 0.840 0.000
D61.2 Aplastic anaemia due to other external agents
0.160 0.840 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.151 0.849 0.000
E50 Vitamin A deficiency
0.151 0.849 0.000
E60 Dietary zinc deficiency
0.151 0.849 0.000
E59 Dietary selenium deficiency
0.151 0.849 0.000
E52 Niacin deficiency [pellagra]
0.151 0.849 0.000
D61.1 Drug-induced aplastic anaemia
0.148 0.852 0.000
E56 Other vitamin deficiencies
0.147 0.853 0.000
L44.0 Pityriasis rubra pilaris
0.145 0.854 0.000
L44.9 Papulosquamous disorder, unspecified
0.140 0.860 0.000
L44.8 Other specified papulosquamous disorders
0.140 0.860 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.140 0.860 0.000
L44.3 Lichen ruber moniliformis
0.140 0.860 0.000
L44.2 Lichen striatus
0.140 0.860 0.000
L44.1 Lichen nitidus
0.140 0.860 0.000
E51.2 Wernicke's encephalopathy
0.139 0.861 0.000
L41.9 Parapsoriasis, unspecified
0.137 0.863 0.000
L41.8 Other parapsoriasis
0.137 0.863 0.000
L41.5 Retiform parapsoriasis
0.137 0.863 0.000
L41.4 Large plaque parapsoriasis
0.137 0.863 0.000
L41.3 Small plaque parapsoriasis
0.137 0.863 0.000
L41.2 Lymphomatoid papulosis
0.137 0.863 0.000
L41.1 Pityriasis lichenoides chronica
0.137 0.863 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.137 0.863 0.000
J47 Bronchiectasis
0.000 0.864 0.136
E34.0 Carcinoid syndrome
0.134 0.865 0.002
D60.9 Acquired pure red cell aplasia, unspecified
0.135 0.865 0.000
E58 Dietary calcium deficiency
0.133 0.867 0.000
E54 Ascorbic acid deficiency
0.132 0.867 0.000
D60.8 Other acquired pure red cell aplasias
0.130 0.870 0.000
D60.1 Transient acquired pure red cell aplasia
0.130 0.870 0.000
D60.0 Chronic acquired pure red cell aplasia
0.130 0.870 0.000
E67.8 Other specified hyperalimentation
0.115 0.876 0.009
E67.3 Hypervitaminosis D
0.115 0.876 0.009
E67.2 Megavitamin-B6 syndrome
0.115 0.876 0.009
E67.1 Hypercarotenaemia
0.115 0.876 0.009
E67.0 Hypervitaminosis A
0.115 0.876 0.009
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.876 0.124
E63.9 Nutritional deficiency, unspecified
0.123 0.877 0.000
E51.9 Thiamine deficiency, unspecified
0.121 0.879 0.000
E51.8 Other manifestations of thiamine deficiency
0.121 0.879 0.000
E51.1 Beriberi
0.121 0.879 0.000
E34.9 Endocrine disorder, unspecified
0.116 0.882 0.002
L43 Lichen planus
0.117 0.882 0.000
C60-C63 Malignant neoplasms of male genital organs
0.000 0.882 0.117
E63.8 Other specified nutritional deficiencies
0.115 0.885 0.000
E63.1 Imbalance of constituents of food intake
0.115 0.885 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.115 0.885 0.000
E50.9 Vitamin A deficiency, unspecified
0.108 0.891 0.000
E50.8 Other manifestations of vitamin A deficiency
0.108 0.891 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.108 0.891 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.108 0.891 0.000
E50.5 Vitamin A deficiency with night blindness
0.108 0.891 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.108 0.891 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.108 0.891 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.108 0.891 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.108 0.891 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.108 0.891 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.108 0.891 0.000
E64.8 Sequelae of other nutritional deficiencies
0.108 0.891 0.000
E64.3 Sequelae of rickets
0.108 0.891 0.000
E64.2 Sequelae of vitamin C deficiency
0.108 0.891 0.000
E64.1 Sequelae of vitamin A deficiency
0.108 0.891 0.000
E64.0 Sequelae of protein-energy malnutrition
0.108 0.891 0.000
E56.9 Vitamin deficiency, unspecified
0.105 0.894 0.000
E56.8 Deficiency of other vitamins
0.105 0.894 0.000
E56.0 Deficiency of vitamin E
0.105 0.894 0.000
E56.1 Deficiency of vitamin K
0.101 0.899 0.000
E55 Vitamin D deficiency
0.098 0.902 0.000
E83.1 Disorders of iron metabolism
0.000 0.904 0.096
E61 Deficiency of other nutrient elements
0.094 0.906 0.000
L43.0 Hypertrophic lichen planus
0.089 0.911 0.000
J98.4 Other disorders of lung
0.089 0.911 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.087 0.913 0.000
K75.4 Autoimmune hepatitis
0.085 0.915 0.000
L43.3 Subacute (active) lichen planus
0.084 0.915 0.000
L43.2 Lichenoid drug reaction
0.084 0.915 0.000
L43.1 Bullous lichen planus
0.084 0.915 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.000 0.915 0.084
J98 Other respiratory disorders
0.084 0.916 0.000
C60 Malignant neoplasm of penis
0.000 0.916 0.084
K75 Other inflammatory liver diseases
0.080 0.920 0.000
E65 Localised adiposity
0.060 0.923 0.017
K75.8 Other specified inflammatory liver diseases
0.077 0.923 0.000
E04 Other non-toxic goitre
0.077 0.923 0.000
E53 Deficiency of other B group vitamins
0.073 0.927 0.000
J98.2 Interstitial emphysema
0.072 0.928 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.072 0.928 0.000
E55.0 Rickets, active
0.070 0.929 0.000
K73 Chronic hepatitis, not elsewhere classified
0.069 0.931 0.000
L43.8 Other lichen planus
0.068 0.931 0.000
K70-K77 Diseases of liver
0.068 0.932 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.068 0.932 0.000
E61.9 Deficiency of nutrient element, unspecified
0.068 0.932 0.000
E61.8 Deficiency of other specified nutrient elements
0.068 0.932 0.000
E61.7 Deficiency of multiple nutrient elements
0.068 0.932 0.000
E61.6 Vanadium deficiency
0.068 0.932 0.000
E61.5 Molybdenum deficiency
0.068 0.932 0.000
E61.4 Chromium deficiency
0.068 0.932 0.000
E61.3 Manganese deficiency
0.068 0.932 0.000
E61.0 Copper deficiency
0.068 0.932 0.000
J98.6 Disorders of diaphragm
0.066 0.934 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.064 0.936 0.000
C60.0 Prepuce
0.000 0.937 0.063
K73.9 Chronic hepatitis, unspecified
0.062 0.938 0.000
C60.1 Glans penis
0.000 0.938 0.062
D63 Anaemia in chronic diseases classified elsewhere
0.062 0.938 0.000
C63.9 Male genital organ, unspecified
0.000 0.939 0.061
C63.8 Overlapping lesion of male genital organs
0.000 0.939 0.061
C63.7 Other specified male genital organs
0.000 0.939 0.061
C63.2 Scrotum
0.000 0.939 0.061
C63.1 Spermatic cord
0.000 0.939 0.061
C63.0 Epididymis
0.000 0.939 0.061
J98.3 Compensatory emphysema
0.061 0.939 0.000
C60.8 Overlapping lesion of penis
0.000 0.940 0.060
C60.2 Body of penis
0.000 0.940 0.060
K72 Hepatic failure, not elsewhere classified
0.059 0.941 0.000
C62 Malignant neoplasm of testis
0.000 0.942 0.058
K75.2 Nonspecific reactive hepatitis
0.057 0.942 0.000
K75.1 Phlebitis of portal vein
0.057 0.942 0.000
I83 Varicose veins of lower extremities
0.000 0.942 0.058
E61.2 Magnesium deficiency
0.057 0.943 0.000
K90-K93 Other diseases of the digestive system
0.057 0.943 0.000
K72.0 Acute and subacute hepatic failure
0.057 0.943 0.000
K71 Toxic liver disease
0.056 0.944 0.000
E04.8 Other specified non-toxic goitre
0.055 0.945 0.000
E04.0 Non-toxic diffuse goitre
0.055 0.945 0.000
C60.9 Penis, unspecified
0.000 0.945 0.054
E53.1 Pyridoxine deficiency
0.052 0.948 0.000
E53.0 Riboflavin deficiency
0.052 0.948 0.000
K77 Liver disorders in diseases classified elsewhere
0.052 0.948 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.050 0.950 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.050 0.950 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.951 0.049
J98.9 Respiratory disorder, unspecified
0.047 0.952 0.000
K75.0 Abscess of liver
0.047 0.953 0.000
K70 Alcoholic liver disease
0.047 0.953 0.000
K71.0 Toxic liver disease with cholestasis
0.046 0.954 0.000
E11 Non-insulin-dependent diabetes mellitus
0.046 0.954 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.954 0.046
E11.1 With ketoacidosis
0.045 0.955 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.044 0.955 0.000
J98.8 Other specified respiratory disorders
0.043 0.956 0.000
C62.1 Descended testis
0.000 0.956 0.043
K71.9 Toxic liver disease, unspecified
0.043 0.957 0.000
K70.1 Alcoholic hepatitis
0.042 0.958 0.000
C62.0 Undescended testis
0.000 0.958 0.042
K74 Fibrosis and cirrhosis of liver
0.041 0.959 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.041 0.959 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.041 0.959 0.000
K71.8 Toxic liver disease with other disorders of liver
0.040 0.960 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.040 0.960 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.040 0.960 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.040 0.960 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.040 0.960 0.000
K71.2 Toxic liver disease with acute hepatitis
0.040 0.960 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.040 0.960 0.000
K72.1 Chronic hepatic failure
0.040 0.960 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.039 0.961 0.000
K70.0 Alcoholic fatty liver
0.039 0.961 0.000
J98.1 Pulmonary collapse
0.038 0.962 0.000
K75.9 Inflammatory liver disease, unspecified
0.038 0.962 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.038 0.962 0.000
K70.4 Alcoholic hepatic failure
0.037 0.963 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.037 0.963 0.000
E53.9 Vitamin B deficiency, unspecified
0.036 0.964 0.001
K74.0 Hepatic fibrosis
0.036 0.964 0.000
E11.7 With multiple complications
0.036 0.964 0.000
E61.1 Iron deficiency
0.035 0.965 0.000
L43.9 Lichen planus, unspecified
0.034 0.966 0.000
M45-M49 Spondylopathies
0.000 0.966 0.034
E11.6 With other specified complications
0.032 0.968 0.000
E66 Obesity
0.010 0.970 0.020
K74.4 Secondary biliary cirrhosis
0.030 0.970 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.030 0.970 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.029 0.970 0.000
K93.1 Megacolon in Chagas' disease
0.029 0.970 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.029 0.970 0.000
K72.9 Hepatic failure, unspecified
0.029 0.971 0.000
K74.1 Hepatic sclerosis
0.029 0.971 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.028 0.972 0.000
Z83.7 Family history of diseases of the digestive system
0.028 0.972 0.000
K74.3 Primary biliary cirrhosis
0.027 0.973 0.000
E11.0 With coma
0.026 0.974 0.000
K74.6 Other and unspecified cirrhosis of liver
0.025 0.975 0.000
E11.8 With unspecified complications
0.024 0.976 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.003 0.977 0.021
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.023 0.977 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.977 0.023
E83 Disorders of mineral metabolism
0.001 0.978 0.021
E66.1 Drug-induced obesity
0.007 0.978 0.015
M49 Spondylopathies in diseases classified elsewhere
0.000 0.978 0.022
E66.0 Obesity due to excess calories
0.005 0.978 0.016
E11.2 With renal complications
0.021 0.979 0.000
E66.8 Other obesity
0.000 0.979 0.021
K74.5 Biliary cirrhosis, unspecified
0.020 0.980 0.000
S02.60 Fracture of mandible (closed)
0.000 0.981 0.019
J40 Bronchitis, not specified as acute or chronic
0.000 0.981 0.019
E83.3 Disorders of phosphorus metabolism
0.000 0.981 0.019
M48 Other spondylopathies
0.000 0.982 0.018
E53.8 Deficiency of other specified B group vitamins
0.017 0.983 0.000
E55.9 Vitamin D deficiency, unspecified
0.017 0.983 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.983 0.017
E70-E90 Metabolic disorders
0.016 0.984 0.001
E83.8 Other disorders of mineral metabolism
0.001 0.984 0.015
E83.2 Disorders of zinc metabolism
0.001 0.984 0.015
E83.0 Disorders of copper metabolism
0.001 0.984 0.015
E89.0 Postprocedural hypothyroidism
0.016 0.984 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.984 0.016
M49.4 Neuropathic spondylopathy
0.000 0.984 0.016
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.984 0.016
M49.2 Enterobacterial spondylitis
0.000 0.984 0.016
M49.1 Brucella spondylitis
0.000 0.984 0.016
M49.0 Tuberculosis of spine
0.000 0.984 0.016
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.016 0.984 0.000
J95-J99 Other diseases of the respiratory system
0.016 0.984 0.000
K70.3 Alcoholic cirrhosis of liver
0.015 0.985 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.000 0.985 0.015
D63.8 Anaemia in other chronic diseases classified elsewhere
0.015 0.985 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.985 0.014
E11.5 With peripheral circulatory complications
0.015 0.985 0.000
K70.9 Alcoholic liver disease, unspecified
0.014 0.986 0.000
M48.9 Spondylopathy, unspecified
0.000 0.986 0.014
E73 Lactose intolerance
0.013 0.986 0.000
H00.1 Chalazion
0.000 0.986 0.014
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.000 0.987 0.013
M48.4 Fatigue fracture of vertebra
0.000 0.987 0.013
M48.3 Traumatic spondylopathy
0.000 0.987 0.013
M48.2 Kissing spine
0.000 0.987 0.013
M48.1 Ankylosing hyperostosis [Forestier]
0.000 0.987 0.013
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.987 0.013
E89.3 Postprocedural hypopituitarism
0.013 0.987 0.000
H20.9 Iridocyclitis, unspecified
0.000 0.987 0.013
J42 Unspecified chronic bronchitis
0.000 0.987 0.013
M46 Other inflammatory spondylopathies
0.000 0.987 0.013
E83.4 Disorders of magnesium metabolism
0.000 0.987 0.013
E11.3 With ophthalmic complications
0.013 0.987 0.000
E74 Other disorders of carbohydrate metabolism
0.012 0.987 0.000
E88 Other metabolic disorders
0.012 0.988 0.000
D63.0 Anaemia in neoplastic disease
0.012 0.988 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.988 0.012
M48.8 Other specified spondylopathies
0.000 0.988 0.012
E77 Disorders of glycoprotein metabolism
0.011 0.988 0.001
E76 Disorders of glycosaminoglycan metabolism
0.011 0.988 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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