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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28446907
log Bayes Factor = 22.322
Chromosome 5   position 109,149,543  (GRCh37) Explore rs28446907 on Ensembl!
Variant rs28446907 is part of Cluster X0293

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K29 Gastritis and duodenitis
0.999 0.001 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
N30-N39 Other diseases of urinary system
0.996 0.004 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
Chapter II Neoplasms
0.992 0.008 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.990 0.010 0.000
Z53.8 Procedure not carried out for other reasons
0.990 0.010 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.990 0.010 0.000
K70-K77 Diseases of liver
0.990 0.010 0.000
M16 Coxarthrosis [arthrosis of hip]
0.986 0.014 0.000
C50-C50 Malignant neoplasm of breast
0.985 0.015 0.000
M45-M49 Spondylopathies
0.985 0.015 0.000
N39 Other disorders of urinary system
0.984 0.016 0.000
K29.8 Duodenitis
0.981 0.019 0.000
C50 Malignant neoplasm of breast
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
M17 Gonarthrosis [arthrosis of knee]
0.979 0.021 0.000
N92 Excessive, frequent and irregular menstruation
0.979 0.021 0.000
K50-K52 Noninfective enteritis and colitis
0.976 0.024 0.000
K76 Other diseases of liver
0.974 0.026 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.969 0.031 0.000
N39.0 Urinary tract infection, site not specified
0.968 0.032 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.963 0.037 0.000
M25 Other joint disorders, not elsewhere classified
0.960 0.040 0.000
N80 Endometriosis
0.958 0.042 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.958 0.042 0.000
K29.6 Other gastritis
0.957 0.043 0.000
Chapter X Diseases of the respiratory system
0.957 0.043 0.000
K29.1 Other acute gastritis
0.957 0.043 0.000
K25 Gastric ulcer
0.950 0.050 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.948 0.052 0.000
D00-D09 In situ neoplasms
0.943 0.057 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.940 0.060 0.000
M23 Internal derangement of knee
0.939 0.061 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.939 0.061 0.000
C50.9 Breast, unspecified
0.938 0.062 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.937 0.063 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.936 0.064 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.934 0.066 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.933 0.067 0.000
N17-N19 Renal failure
0.930 0.070 0.000
N10-N16 Renal tubulo-interstitial diseases
0.929 0.071 0.000
N39.4 Other specified urinary incontinence
0.929 0.071 0.000
C50.8 Overlapping lesion of breast
0.928 0.072 0.000
K52 Other non-infective gastro-enteritis and colitis
0.924 0.076 0.000
M47 Spondylosis
0.919 0.081 0.000
M70-M79 Other soft tissue disorders
0.919 0.081 0.000
M16.1 Other primary coxarthrosis
0.918 0.082 0.000
K29.7 Gastritis, unspecified
0.911 0.089 0.000
Z13 Special screening examination for other diseases and disorders
0.909 0.091 0.000
M16.9 Coxarthrosis, unspecified
0.906 0.094 0.000
C64-C68 Malignant neoplasms of urinary tract
0.904 0.096 0.000
M17.1 Other primary gonarthrosis
0.900 0.100 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.900 0.100 0.000
J95-J99 Other diseases of the respiratory system
0.898 0.102 0.000
D05 Carcinoma in situ of breast
0.898 0.102 0.000
K35-K38 Diseases of appendix
0.897 0.103 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.896 0.104 0.000
M48 Other spondylopathies
0.896 0.104 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.104 0.000
Z53.9 Procedure not carried out, unspecified reason
0.894 0.106 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
C50.4 Upper-outer quadrant of breast
0.893 0.107 0.000
K51 Ulcerative colitis
0.888 0.112 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.886 0.114 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.886 0.114 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.884 0.116 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.883 0.117 0.000
N85.2 Hypertrophy of uterus
0.882 0.118 0.000
N19 Unspecified renal failure
0.882 0.118 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.878 0.122 0.000
M47.8 Other spondylosis
0.876 0.124 0.000
M17.9 Gonarthrosis, unspecified
0.872 0.128 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.870 0.130 0.000
J09-J18 Influenza and pneumonia
0.867 0.133 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.865 0.135 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.862 0.138 0.000
N80.9 Endometriosis, unspecified
0.862 0.138 0.000
N88 Other noninflammatory disorders of cervix uteri
0.862 0.138 0.000
N87 Dysplasia of cervix uteri
0.862 0.138 0.000
Z48 Other surgical follow-up care
0.862 0.138 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.860 0.140 0.000
K31 Other diseases of stomach and duodenum
0.859 0.141 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.857 0.143 0.000
M18 Arthrosis of first carpometacarpal joint
0.856 0.144 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.856 0.144 0.000
K29.4 Chronic atrophic gastritis
0.855 0.145 0.000
M79.6 Pain in limb
0.853 0.147 0.000
O60-O75 Complications of labour and delivery
0.849 0.151 0.000
D05.1 Intraductal carcinoma in situ
0.848 0.152 0.000
S80-S89 Injuries to the knee and lower leg
0.847 0.153 0.000
K12 Stomatitis and related lesions
0.846 0.154 0.000
E00-E07 Disorders of thyroid gland
0.845 0.155 0.000
K74 Fibrosis and cirrhosis of liver
0.844 0.156 0.000
N80.3 Endometriosis of pelvic peritoneum
0.842 0.158 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.839 0.161 0.000
J60-J70 Lung diseases due to external agents
0.839 0.161 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.838 0.162 0.000
N13 Obstructive and reflux uropathy
0.836 0.164 0.000
E70-E90 Metabolic disorders
0.835 0.165 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.832 0.168 0.000
Z03.8 Observation for other suspected diseases and conditions
0.832 0.168 0.000
M48.0 Spinal stenosis
0.832 0.168 0.000
M34 Systemic sclerosis
0.831 0.169 0.000
K35 Acute appendicitis
0.828 0.172 0.000
N20-N23 Urolithiasis
0.828 0.172 0.000
B95-B98 Bacterial, viral and other infectious agents
0.824 0.176 0.000
J90-J94 Other diseases of pleura
0.820 0.180 0.000
M16.0 Primary coxarthrosis, bilateral
0.814 0.186 0.000
M45 Ankylosing spondylitis
0.813 0.187 0.000
K25.7 Chronic without haemorrhage or perforation
0.813 0.187 0.000
N73 Other female pelvic inflammatory diseases
0.812 0.188 0.000
M79.66 Pain in limb (Lower leg)
0.810 0.190 0.000
M25.4 Effusion of joint
0.808 0.192 0.000
N36 Other disorders of urethra
0.804 0.196 0.000
Q60-Q64 Congenital malformations of the urinary system
0.804 0.196 0.000
C67 Malignant neoplasm of bladder
0.804 0.196 0.000
K01 Embedded and impacted teeth
0.801 0.199 0.000
M25.3 Other instability of joint
0.801 0.199 0.000
Y84.8 Other medical procedures
0.801 0.199 0.000
N72 Inflammatory disease of cervix uteri
0.801 0.199 0.000
S70-S79 Injuries to the hip and thigh
0.800 0.200 0.000
M17.0 Primary gonarthrosis, bilateral
0.798 0.202 0.000
N30 Cystitis
0.798 0.202 0.000
M50-M54 Other dorsopathies
0.797 0.203 0.000
S50-S59 Injuries to the elbow and forearm
0.796 0.204 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.795 0.205 0.000
Y83.6 Removal of other organ (partial) (total)
0.795 0.205 0.000
K02 Dental caries
0.794 0.206 0.000
E03 Other hypothyroidism
0.794 0.206 0.000
A00-A09 Intestinal infectious diseases
0.793 0.207 0.000
E83 Disorders of mineral metabolism
0.792 0.208 0.000
M21 Other acquired deformities of limbs
0.791 0.209 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.791 0.209 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.791 0.209 0.000
J98 Other respiratory disorders
0.790 0.210 0.000
N85.4 Malposition of uterus
0.790 0.210 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.785 0.215 0.000
Chapter VI Diseases of the nervous system
0.785 0.215 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.783 0.217 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.782 0.218 0.000
M25.5 Pain in joint
0.781 0.219 0.000
M17.3 Other posttraumatic gonarthrosis
0.781 0.219 0.000
K52.1 Toxic gastro-enteritis and colitis
0.780 0.220 0.000
Z13.1 Special screening examination for diabetes mellitus
0.780 0.220 0.000
K75 Other inflammatory liver diseases
0.777 0.223 0.000
M47.82 Other spondylosis (Cervical region)
0.776 0.224 0.000
M24 Other specific joint derangements
0.776 0.224 0.000
M05-M14 Inflammatory polyarthropathies
0.776 0.224 0.000
V20-V29 Motorcycle rider injured in transport accident
0.775 0.225 0.000
K25.0 Acute with haemorrhage
0.774 0.226 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.774 0.226 0.000
C50.1 Central portion of breast
0.773 0.227 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.771 0.229 0.000
K14 Diseases of tongue
0.771 0.229 0.000
M25.7 Osteophyte
0.770 0.230 0.000
M31 Other necrotising vasculopathies
0.770 0.230 0.000
D10-D36 Benign neoplasms
0.769 0.231 0.000
Z13.9 Special screening examination, unspecified
0.769 0.231 0.000
L20-L30 Dermatitis and eczema
0.768 0.232 0.000
O70 Perineal laceration during delivery
0.766 0.234 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.766 0.234 0.000
M16.3 Other dysplastic coxarthrosis
0.765 0.234 0.000
M25.9 Joint disorder, unspecified
0.765 0.235 0.000
K51.9 Ulcerative colitis, unspecified
0.765 0.235 0.000
Z45 Adjustment and management of implanted device
0.763 0.237 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.761 0.239 0.000
V80-V89 Other land transport accidents
0.760 0.240 0.000
N13.3 Other and unspecified hydronephrosis
0.760 0.240 0.000
E10-E14 Diabetes mellitus
0.759 0.241 0.000
M46 Other inflammatory spondylopathies
0.759 0.241 0.000
K31.8 Other specified diseases of stomach and duodenum
0.758 0.242 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.758 0.242 0.000
K29.3 Chronic superficial gastritis
0.758 0.242 0.000
T85.2 Mechanical complication of intraocular lens
0.758 0.242 0.000
Z04 Examination and observation for other reasons
0.757 0.243 0.000
E03.9 Hypothyroidism, unspecified
0.757 0.243 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.754 0.246 0.000
C50.0 Nipple and areola
0.753 0.246 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.753 0.247 0.000
K08 Other disorders of teeth and supporting structures
0.753 0.247 0.000
D17 Benign lipomatous neoplasm
0.752 0.248 0.000
N92.4 Excessive bleeding in the premenopausal period
0.752 0.248 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.752 0.248 0.000
N20 Calculus of kidney and ureter
0.752 0.248 0.000
K76.8 Other specified diseases of liver
0.751 0.249 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.751 0.249 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.751 0.249 0.000
J00-J06 Acute upper respiratory infections
0.750 0.250 0.000
T92 Sequelae of injuries of upper limb
0.749 0.251 0.000
O80-O84 Delivery
0.749 0.251 0.000
N97 Female infertility
0.748 0.252 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.747 0.253 0.000
W20-W49 Exposure to inanimate mechanical forces
0.747 0.253 0.000
M47.89 Other spondylosis (Site unspecified)
0.745 0.255 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.744 0.256 0.000
K04 Diseases of pulp and periapical tissues
0.743 0.257 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.742 0.258 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
Z03.4 Observation for suspected myocardial infarction
0.741 0.259 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.741 0.259 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.740 0.259 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
M35 Other systemic involvement of connective tissue
0.740 0.260 0.000
N80.1 Endometriosis of ovary
0.740 0.260 0.000
V10-V19 Pedal cyclist injured in transport accident
0.740 0.260 0.000
Q61 Cystic kidney disease
0.738 0.261 0.000
B65-B83 Helminthiases
0.738 0.262 0.000
Y84.6 Urinary catheterisation
0.738 0.262 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.737 0.263 0.000
N73.6 Female pelvic peritoneal adhesions
0.736 0.264 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.736 0.264 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.736 0.264 0.000
S20-S29 Injuries to the thorax
0.736 0.264 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.734 0.266 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.731 0.269 0.000
J69 Pneumonitis due to solids and liquids
0.730 0.270 0.000
N87.0 Mild cervical dysplasia
0.730 0.270 0.000
D50-D53 Nutritional anaemias
0.730 0.270 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.728 0.272 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.728 0.272 0.000
N80.2 Endometriosis of Fallopian tube
0.727 0.273 0.000
S40-S49 Injuries to the shoulder and upper arm
0.727 0.273 0.000
K29.5 Chronic gastritis, unspecified
0.727 0.273 0.000
Z42 Follow-up care involving plastic surgery
0.727 0.273 0.000
S60-S69 Injuries to the wrist and hand
0.727 0.273 0.000
N32 Other disorders of bladder
0.726 0.274 0.000
K76.9 Liver disease, unspecified
0.726 0.274 0.000
M25.8 Other specified joint disorders
0.725 0.275 0.000
K10 Other diseases of jaws
0.725 0.275 0.000
B15-B19 Viral hepatitis
0.725 0.275 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.724 0.276 0.000
K12.1 Other forms of stomatitis
0.724 0.276 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.724 0.276 0.000
N76 Other inflammation of vagina and vulva
0.724 0.276 0.000
D06 Carcinoma in situ of cervix uteri
0.723 0.277 0.000
O72 Postpartum haemorrhage
0.723 0.277 0.000
Y84.0 Cardiac catheterisation
0.723 0.277 0.000
N80.8 Other endometriosis
0.722 0.278 0.000
M79.1 Myalgia
0.721 0.278 0.000
N75 Diseases of Bartholin's gland
0.721 0.279 0.000
B35-B49 Mycoses
0.720 0.280 0.000
J18 Pneumonia, organism unspecified
0.720 0.280 0.000
M79.8 Other specified soft tissue disorders
0.720 0.280 0.000
Z41 Procedures for purposes other than remedying health state
0.719 0.281 0.000
M25.56 Pain in joint (Lower leg)
0.718 0.282 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
K29.9 Gastroduodenitis, unspecified
0.717 0.283 0.000
K29.2 Alcoholic gastritis
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.716 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.716 0.283 0.000
M15 Polyarthrosis
0.716 0.283 0.000
Z33 Pregnant state, incidental
0.716 0.284 0.000
N98 Complications associated with artificial fertilisation
0.715 0.285 0.000
N91 Absent, scanty and rare menstruation
0.715 0.285 0.000
N82 Fistulae involving female genital tract
0.715 0.285 0.000
N96 Habitual aborter
0.715 0.285 0.000
M79.0 Rheumatism, unspecified
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
T93 Sequelae of injuries of lower limb
0.714 0.286 0.000
N37 Urethral disorders in diseases classified elsewhere
0.714 0.286 0.000
N34 Urethritis and urethral syndrome
0.714 0.286 0.000
N33 Bladder disorders in diseases classified elsewhere
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
M34.9 Systemic sclerosis, unspecified
0.714 0.286 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
N10 Acute tubulo-interstitial nephritis
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.288 0.000
N18 Chronic renal failure
0.710 0.290 0.000
T91 Sequelae of injuries of neck and trunk
0.710 0.290 0.000
Z54 Convalescence
0.710 0.290 0.000
Z52 Donors of organs and tissues
0.710 0.290 0.000
Z49 Care involving dialysis
0.710 0.290 0.000
Z44 Fitting and adjustment of external prosthetic device
0.710 0.290 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.710 0.290 0.000
K77 Liver disorders in diseases classified elsewhere
0.709 0.290 0.000
K73 Chronic hepatitis, not elsewhere classified
0.709 0.290 0.000
K71 Toxic liver disease
0.709 0.290 0.000
K72 Hepatic failure, not elsewhere classified
0.709 0.290 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.709 0.291 0.000
C67.2 Lateral wall of bladder
0.709 0.291 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.708 0.292 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.708 0.292 0.000
M16.7 Other secondary coxarthrosis
0.707 0.293 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.707 0.293 0.000
M16.5 Other posttraumatic coxarthrosis
0.707 0.293 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.707 0.293 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.707 0.293 0.000
M49 Spondylopathies in diseases classified elsewhere
0.706 0.294 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.706 0.294 0.000
N39.2 Orthostatic proteinuria, unspecified
0.705 0.294 0.000
N39.1 Persistent proteinuria, unspecified
0.705 0.294 0.000
M50 Cervical disk disorders
0.706 0.294 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.705 0.295 0.000
Z35 Supervision of high-risk pregnancy
0.704 0.296 0.000
K07 Dentofacial anomalies [including malocclusion]
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
Z39 Postpartum care and examination
0.704 0.296 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.297 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
N71 Inflammatory disease of uterus, except cervix
0.703 0.297 0.000
C50.6 Axillary tail of breast
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.297 0.000
Y10-Y34 Event of undetermined intent
0.702 0.297 0.000
Y00-Y09 Assault
0.702 0.297 0.000
X85-X99 Assault
0.702 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.297 0.000
X50-X57 Overexertion, travel and privation
0.702 0.297 0.000
X30-X39 Exposure to forces of nature
0.702 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.297 0.000
X10-X19 Contact with heat and hot substances
0.702 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.297 0.000
W75-W84 Other accidental threats to breathing
0.702 0.297 0.000
W65-W74 Accidental drowning and submersion
0.702 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.702 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.297 0.000
V95-V97 Air and space transport accidents
0.702 0.297 0.000
V90-V94 Water transport accidents
0.702 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.297 0.000
M17.5 Other secondary gonarthrosis
0.702 0.298 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.702 0.298 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.702 0.298 0.000
N92.5 Other specified irregular menstruation
0.702 0.298 0.000
N92.2 Excessive menstruation at puberty
0.702 0.298 0.000
A04 Other bacterial intestinal infections
0.701 0.299 0.000
E83.5 Disorders of calcium metabolism
0.701 0.299 0.000
D04 Carcinoma in situ of skin
0.700 0.299 0.000
M25.46 Effusion of joint (Lower leg)
0.700 0.300 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.700 0.300 0.000
D51 Vitamin B12 deficiency anaemia
0.700 0.300 0.000
K76.7 Hepatorenal syndrome
0.699 0.301 0.000
K76.5 Hepatic veno-occlusive disease
0.699 0.301 0.000
K76.4 Peliosis hepatis
0.699 0.301 0.000
K76.3 Infarction of liver
0.699 0.301 0.000
K76.2 Central haemorrhagic necrosis of liver
0.699 0.301 0.000
K76.1 Chronic passive congestion of liver
0.699 0.301 0.000
K09 Cysts of oral region, not elsewhere classified
0.697 0.303 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.696 0.304 0.000
Z48.0 Attention to surgical dressings and sutures
0.696 0.304 0.000
K25.4 Chronic or unspecified with haemorrhage
0.695 0.304 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.693 0.307 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.693 0.307 0.000
N00-N08 Glomerular diseases
0.693 0.307 0.000
O00-O08 Pregnancy with abortive outcome
0.693 0.307 0.000
M23.3 Other meniscus derangements
0.692 0.307 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.691 0.309 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.691 0.309 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.691 0.309 0.000
T66-T78 Other and unspecified effects of external causes
0.690 0.309 0.000
Z48.9 Surgical follow-up care, unspecified
0.690 0.310 0.000
S90-S99 Injuries to the ankle and foot
0.690 0.310 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.690 0.310 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.690 0.310 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.690 0.310 0.000
Z46 Fitting and adjustment of other devices
0.689 0.310 0.000
K01.1 Impacted teeth
0.689 0.311 0.000
Chapter VIII Diseases of the ear and mastoid process
0.689 0.311 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.688 0.312 0.000
M25.2 Flail joint
0.688 0.312 0.000
M25.1 Fistula of joint
0.688 0.312 0.000
M25.0 Haemarthrosis
0.688 0.312 0.000
K12.2 Cellulitis and abscess of mouth
0.688 0.312 0.000
M25.34 Other instability of joint (Hand)
0.688 0.312 0.000
N80.6 Endometriosis in cutaneous scar
0.687 0.313 0.000
N80.5 Endometriosis of intestine
0.687 0.313 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.687 0.313 0.000
K03 Other diseases of hard tissues of teeth
0.687 0.313 0.000
K00 Disorders of tooth development and eruption
0.687 0.313 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.687 0.313 0.000
E88 Other metabolic disorders
0.686 0.314 0.000
Z31 Procreative management
0.686 0.314 0.000
S82 Fracture of lower leg, including ankle
0.685 0.315 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.684 0.316 0.000
C50.5 Lower-outer quadrant of breast
0.684 0.316 0.000
E14 Unspecified diabetes mellitus
0.684 0.316 0.000
K74.3 Primary biliary cirrhosis
0.683 0.316 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.683 0.317 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.683 0.317 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.682 0.318 0.000
Y83.0 Surgical operation with transplant of whole organ
0.682 0.318 0.000
M79.5 Residual foreign body in soft tissue
0.682 0.318 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.682 0.318 0.000
N39.8 Other specified disorders of urinary system
0.681 0.318 0.000
A30-A49 Other bacterial diseases
0.681 0.319 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.681 0.319 0.000
K25.5 Chronic or unspecified with perforation
0.681 0.319 0.000
K25.2 Acute with both haemorrhage and perforation
0.681 0.319 0.000
K25.1 Acute with perforation
0.681 0.319 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.681 0.319 0.000
K50 Crohn's disease [regional enteritis]
0.680 0.319 0.000
M19 Other arthrosis
0.680 0.320 0.000
M86-M90 Other osteopathies
0.680 0.320 0.000
N95 Menopausal and other perimenopausal disorders
0.680 0.320 0.000
Q50-Q56 Congenital malformations of genital organs
0.680 0.320 0.000
J93 Pneumothorax
0.680 0.320 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.680 0.320 0.000
M13 Other arthritis
0.679 0.321 0.000
N40-N51 Diseases of male genital organs
0.679 0.321 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.678 0.322 0.000
K51.2 Ulcerative (chronic) proctitis
0.678 0.322 0.000
D09 Carcinoma in situ of other and unspecified sites
0.677 0.323 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.677 0.323 0.000
O70.0 First degree perineal laceration during delivery
0.677 0.323 0.000
K02.9 Dental caries, unspecified
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.676 0.324 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.676 0.324 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.676 0.324 0.000
E20-E35 Disorders of other endocrine glands
0.675 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.675 0.325 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.675 0.325 0.000
Z10 Routine general health check-up of defined subpopulation
0.674 0.326 0.000
M23.9 Internal derangement of knee, unspecified
0.673 0.326 0.000
M23.5 Chronic instability of knee
0.673 0.326 0.000
M23.4 Loose body in knee
0.673 0.326 0.000
M23.1 Discoid meniscus (congenital)
0.673 0.326 0.000
M23.0 Cystic meniscus
0.673 0.326 0.000
M71 Other bursopathies
0.673 0.326 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.673 0.327 0.000
N85.7 Haematometra
0.673 0.327 0.000
N85.6 Intra-uterine synechiae
0.673 0.327 0.000
N85.5 Inversion of uterus
0.673 0.327 0.000
N85.3 Subinvolution of uterus
0.673 0.327 0.000
N85.1 Endometrial adenomatous hyperplasia
0.673 0.327 0.000
N20.0 Calculus of kidney
0.672 0.328 0.000
T87 Complications peculiar to reattachment and amputation
0.672 0.328 0.000
T86 Failure and rejection of transplanted organs and tissues
0.672 0.328 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
L29 Pruritus
0.672 0.328 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.672 0.328 0.000
N92.3 Ovulation bleeding
0.671 0.328 0.000
M79.63 Pain in limb (Forearm)
0.671 0.328 0.000
S32 Fracture of lumbar spine and pelvis
0.671 0.329 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.670 0.330 0.000
J90 Pleural effusion, not elsewhere classified
0.670 0.330 0.000
E40-E46 Malnutrition
0.669 0.331 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.669 0.331 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.669 0.331 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.669 0.331 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.669 0.331 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.668 0.332 0.000
Z48.8 Other specified surgical follow-up care
0.668 0.332 0.000
Z34 Supervision of normal pregnancy
0.668 0.332 0.000
K11 Diseases of salivary glands
0.667 0.333 0.000
M79.64 Pain in limb (Hand)
0.667 0.333 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.667 0.333 0.000
M48.09 Spinal stenosis (Site unspecified)
0.667 0.333 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.666 0.334 0.000
N15 Other renal tubulo-interstitial diseases
0.666 0.334 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.666 0.334 0.000
N11 Chronic tubulo-interstitial nephritis
0.666 0.334 0.000
Z40 Prophylactic surgery
0.666 0.334 0.000
K31.5 Obstruction of duodenum
0.666 0.334 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.665 0.335 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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