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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844746
log Bayes Factor = 52.5871
Chromosome 6   position 30,339,602  (GRCh37) Explore rs2844746 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.002 0.998
M06.9 Rheumatoid arthritis, unspecified
0.000 0.006 0.994
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.015 0.985
E10.1 With ketoacidosis
0.000 0.015 0.985
E10.4 With neurological complications
0.000 0.053 0.947
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.061 0.939
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.067 0.933
E10.2 With renal complications
0.000 0.075 0.925
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.114 0.886
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.130 0.870
E10.8 With unspecified complications
0.000 0.135 0.865
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.136 0.864
E10-E14 Diabetes mellitus
0.000 0.143 0.857
E10.0 With coma
0.000 0.172 0.828
E13 Other specified diabetes mellitus
0.000 0.179 0.821
E13.9 Without complications
0.000 0.205 0.795
E14 Unspecified diabetes mellitus
0.000 0.212 0.788
G20 Parkinson's disease
0.768 0.232 0.000
G20-G26 Extrapyramidal and movement disorders
0.767 0.233 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.237 0.763
G24 Dystonia
0.762 0.238 0.000
G35 Multiple sclerosis
0.759 0.241 0.000
E14.3 With ophthalmic complications
0.000 0.251 0.749
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.254 0.746
G24.8 Other dystonia
0.702 0.298 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.693 0.307 0.000
E10.6 With other specified complications
0.000 0.319 0.681
E10.7 With multiple complications
0.000 0.320 0.680
E10.5 With peripheral circulatory complications
0.000 0.333 0.666
G25 Other extrapyramidal and movement disorders
0.664 0.336 0.000
G24.3 Spasmodic torticollis
0.654 0.346 0.000
G24.0 Drug-induced dystonia
0.643 0.357 0.000
E14.8 With unspecified complications
0.000 0.358 0.642
G25.8 Other specified extrapyramidal and movement disorders
0.641 0.359 0.000
G24.9 Dystonia, unspecified
0.635 0.365 0.000
G24.5 Blepharospasm
0.627 0.373 0.000
E14.2 Withrenal complications
0.000 0.385 0.615
E12 Malnutrition-related diabetes mellitus
0.000 0.385 0.614
G37 Other demyelinating diseases of central nervous system
0.614 0.386 0.000
G24.1 Idiopathic familial dystonia
0.608 0.392 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.594 0.406 0.000
E13.8 With unspecified complications
0.000 0.411 0.588
E13.7 With multiple complications
0.000 0.411 0.588
E13.6 With other specified complications
0.000 0.411 0.588
E13.5 With peripheral circulatory complications
0.000 0.411 0.588
E13.4 With neurological complications
0.000 0.411 0.588
E13.3 With ophthalmic complications
0.000 0.411 0.588
E13.2 With renal complications
0.000 0.411 0.588
E13.1 With ketoacidosis
0.000 0.411 0.588
E13.0 With coma
0.000 0.411 0.588
E14.4 With neurological complications
0.000 0.412 0.588
E14.1 With ketoacidosis
0.000 0.417 0.583
Chapter VI Diseases of the nervous system
0.582 0.418 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.576 0.424 0.000
E14.7 With multiple complications
0.000 0.435 0.565
E14.6 With other specified complications
0.000 0.435 0.565
E14.0 With coma
0.000 0.435 0.565
G21 Secondary Parkinsonism
0.565 0.435 0.000
G25.5 Other chorea
0.555 0.445 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.550 0.450 0.000
G22 Parkinsonism in diseases classified elsewhere
0.550 0.450 0.000
G24.4 Idiopathic orofacial dystonia
0.546 0.453 0.000
G24.2 Idiopathic nonfamilial dystonia
0.546 0.453 0.000
E14.5 With peripheral circulatory complications
0.000 0.468 0.531
K90 Intestinal malabsorption
0.000 0.476 0.524
G23 Other degenerative diseases of basal ganglia
0.515 0.484 0.000
G25.3 Myoclonus
0.515 0.485 0.000
I83 Varicose veins of lower extremities
0.512 0.488 0.000
G30-G32 Other degenerative diseases of the nervous system
0.504 0.496 0.000
G25.1 Drug-induced tremor
0.487 0.513 0.000
G36 Other acute disseminated demyelination
0.485 0.515 0.000
G30 Alzheimer's disease
0.477 0.523 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.476 0.524 0.000
G25.4 Drug-induced chorea
0.476 0.524 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.525 0.475
I83.1 Varicose veins of lower extremities with inflammation
0.475 0.525 0.000
G30.0 Alzheimer's disease with early onset
0.452 0.548 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.443 0.557 0.000
E12.9 Without complications
0.000 0.559 0.441
E12.8 With unspecified complications
0.000 0.559 0.441
E12.7 With multiple complications
0.000 0.559 0.441
E12.6 With other specified complications
0.000 0.559 0.441
E12.5 With peripheral circulatory complications
0.000 0.559 0.441
E12.4 With neurological complications
0.000 0.559 0.441
E12.3 With ophthalmic complications
0.000 0.559 0.441
E12.2 With renal complications
0.000 0.559 0.441
E12.1 With ketoacidosis
0.000 0.559 0.441
E12.0 With coma
0.000 0.559 0.441
G37.5 Concentric sclerosis [Balo]
0.440 0.560 0.000
G37.4 Subacute necrotising myelitis
0.440 0.560 0.000
G37.2 Central pontine myelinolysis
0.440 0.560 0.000
G37.1 Central demyelination of corpus callosum
0.440 0.560 0.000
G37.0 Diffuse sclerosis
0.440 0.560 0.000
G21.0 Malignant neuroleptic syndrome
0.429 0.571 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.425 0.575 0.000
K90.8 Other intestinal malabsorption
0.000 0.580 0.420
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.585 0.415
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.407 0.593 0.000
G21.9 Secondary Parkinsonism, unspecified
0.405 0.595 0.000
G21.8 Other secondary Parkinsonism
0.405 0.595 0.000
G21.4 Vascular parkinsonism
0.405 0.595 0.000
G21.3 Postencephalitic Parkinsonism
0.405 0.595 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.405 0.595 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.404 0.596 0.000
G30.8 Other Alzheimer's disease
0.396 0.604 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.393 0.606 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.624 0.376
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.624 0.376
K90.1 Tropical sprue
0.000 0.624 0.376
G23.9 Degenerative disease of basal ganglia, unspecified
0.370 0.630 0.000
G23.3 Multiple system atrophy, cerebellar type
0.370 0.630 0.000
G23.2 Striatonigral degeneration
0.370 0.630 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.370 0.630 0.000
G23.0 Hallervorden-Spatz disease
0.370 0.630 0.000
G30.9 Alzheimer's disease, unspecified
0.365 0.635 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.359 0.641 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.356 0.644 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.356 0.644 0.000
G36.9 Acute disseminated demyelination, unspecified
0.348 0.652 0.000
G36.8 Other specified acute disseminated demyelination
0.348 0.652 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.348 0.652 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.335 0.664 0.000
G36.0 Neuromyelitis optica [Devic]
0.335 0.664 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.675 0.325
G11 Hereditary ataxia
0.321 0.679 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.320 0.680 0.000
G10 Huntington's disease
0.318 0.682 0.000
G25.2 Other specified forms of tremor
0.299 0.700 0.001
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.292 0.708 0.000
G14 Postpolio syndrome
0.292 0.708 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.283 0.717 0.000
M06 Other rheumatoid arthritis
0.000 0.723 0.277
G30.1 Alzheimer's disease with late onset
0.274 0.726 0.000
G11.4 Hereditary spastic paraplegia
0.265 0.735 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.257 0.743 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.255 0.745 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.250 0.750 0.000
G03 Meningitis due to other and unspecified causes
0.248 0.752 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.241 0.759 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.231 0.768 0.000
G11.8 Other hereditary ataxias
0.230 0.769 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.230 0.769 0.000
G11.2 Late-onset cerebellar ataxia
0.230 0.769 0.000
G11.0 Congenital nonprogressive ataxia
0.230 0.769 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.229 0.770 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.771 0.229
G11.9 Hereditary ataxia, unspecified
0.227 0.773 0.000
G11.1 Early-onset cerebellar ataxia
0.225 0.774 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.223 0.777 0.000
G25.0 Essential tremor
0.218 0.782 0.000
G70-G73 Diseases of myoneural junction and muscle
0.218 0.782 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.210 0.790 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.210 0.790 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.210 0.790 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.210 0.790 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.210 0.790 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.207 0.793 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.203 0.797 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.203 0.797 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.203 0.797 0.000
E14.9 Without complications
0.000 0.797 0.203
G09 Sequelae of inflammatory diseases of central nervous system
0.203 0.797 0.000
M06.2 Rheumatoid bursitis
0.000 0.801 0.199
M06.1 Adult-onset Still's disease
0.000 0.801 0.199
M06.8 Other specified rheumatoid arthritis
0.000 0.803 0.197
G06.2 Extradural and subdural abscess, unspecified
0.196 0.804 0.000
L40.9 Psoriasis, unspecified
0.196 0.804 0.000
G03.9 Meningitis, unspecified
0.196 0.804 0.000
G12 Spinal muscular atrophy and related syndromes
0.193 0.806 0.001
G80-G83 Cerebral palsy and other paralytic syndromes
0.193 0.807 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.809 0.191
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.188 0.812 0.000
G03.8 Meningitis due to other specified causes
0.178 0.822 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.178 0.822 0.000
G03.1 Chronic meningitis
0.178 0.822 0.000
G03.0 Nonpyogenic meningitis
0.178 0.822 0.000
G31.2 Degeneration of nervous system due to alcohol
0.175 0.825 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.174 0.826 0.000
G60 Hereditary and idiopathic neuropathy
0.173 0.827 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.830 0.169
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.834 0.166
G06.1 Intraspinal abscess and granuloma
0.165 0.835 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.836 0.164
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.836 0.164
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.836 0.164
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.836 0.164
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.836 0.164
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.836 0.164
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.836 0.164
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.836 0.164
G01 Meningitis in bacterial diseases classified elsewhere
0.163 0.837 0.000
L40 Psoriasis
0.161 0.839 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.160 0.840 0.000
E83 Disorders of mineral metabolism
0.157 0.843 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.156 0.843 0.000
G64 Other disorders of peripheral nervous system
0.153 0.847 0.000
G00 Bacterial meningitis, not elsewhere classified
0.152 0.848 0.000
L40.5 Arthropathic psoriasis
0.152 0.848 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.849 0.151
E50-E64 Other nutritional deficiencies
0.000 0.849 0.151
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.150 0.849 0.000
G04.1 Tropical spastic paraplegia
0.150 0.849 0.000
G04.0 Acute disseminated encephalitis
0.150 0.849 0.000
G60.0 Hereditary motor and sensory neuropathy
0.147 0.853 0.000
G31.0 Circumscribed brain atrophy
0.145 0.855 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.857 0.143
M06.18 Adult-onset Still's disease (Other)
0.000 0.857 0.143
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.857 0.143
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.857 0.143
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.857 0.143
M06.14 Adult-onset Still's disease (Hand)
0.000 0.857 0.143
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.857 0.143
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.857 0.143
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.857 0.143
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.857 0.143
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.857 0.143
M06.28 Rheumatoid bursitis (Other)
0.000 0.857 0.143
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.857 0.143
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.857 0.143
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.857 0.143
M06.24 Rheumatoid bursitis (Hand)
0.000 0.857 0.143
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.857 0.143
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.857 0.143
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.857 0.143
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.857 0.143
L40.8 Other psoriasis
0.142 0.858 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.858 0.141
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.858 0.141
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.858 0.141
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.858 0.141
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.858 0.141
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.858 0.141
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.858 0.141
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.858 0.141
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.858 0.141
E16 Other disorders of pancreatic internal secretion
0.000 0.859 0.141
G31.9 Degenerative disease of nervous system, unspecified
0.140 0.860 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.860 0.140
G12.9 Spinal muscular atrophy, unspecified
0.139 0.861 0.001
G12.8 Other spinal muscular atrophies and related syndromes
0.139 0.861 0.001
G12.1 Other inherited spinal muscular atrophy
0.139 0.861 0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.139 0.861 0.001
M06.3 Rheumatoid nodule
0.000 0.861 0.139
E55 Vitamin D deficiency
0.000 0.861 0.138
G82 Paraplegia and tetraplegia
0.137 0.863 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.863 0.137
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.135 0.865 0.000
G02.1 Meningitis in mycoses
0.135 0.865 0.000
G70 Myasthenia gravis and other myoneural disorders
0.135 0.865 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.870 0.130
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.873 0.127
G60.8 Other hereditary and idiopathic neuropathies
0.126 0.874 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.125 0.874 0.000
G82.1 Spastic paraplegia
0.125 0.875 0.000
L40.3 Pustulosis palmaris et plantaris
0.125 0.875 0.000
G71 Primary disorders of muscles
0.124 0.875 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.124 0.875 0.000
E53 Deficiency of other B group vitamins
0.000 0.876 0.124
G60.3 Idiopathic progressive neuropathy
0.124 0.876 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.124 0.876 0.000
G60.1 Refsum's disease
0.124 0.876 0.000
G80 Infantile cerebral palsy
0.121 0.878 0.000
E00-E07 Disorders of thyroid gland
0.000 0.880 0.120
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.881 0.119
G06.0 Intracranial abscess and granuloma
0.117 0.882 0.000
L40.2 Acrodermatitis continua
0.116 0.884 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.885 0.115
E83.3 Disorders of phosphorus metabolism
0.114 0.886 0.000
E03 Other hypothyroidism
0.000 0.886 0.114
E03.9 Hypothyroidism, unspecified
0.000 0.887 0.113
E83.8 Other disorders of mineral metabolism
0.113 0.887 0.000
E83.2 Disorders of zinc metabolism
0.113 0.887 0.000
E83.0 Disorders of copper metabolism
0.113 0.887 0.000
G73.7 Myopathy other diseases classified elsewhere
0.112 0.887 0.000
G73.6 Myopathy in metabolic diseases
0.112 0.887 0.000
G73.5 Myopathy in endocrine diseases
0.112 0.887 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.112 0.887 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.112 0.887 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.112 0.887 0.000
G73.1 Eaton-Lambert syndrome
0.112 0.887 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.112 0.887 0.000
G00.8 Other bacterial meningitis
0.109 0.891 0.000
G00.3 Staphylococcal meningitis
0.109 0.891 0.000
G00.0 Haemophilus meningitis
0.109 0.891 0.000
G00.2 Streptococcal meningitis
0.109 0.891 0.000
L40.4 Guttate psoriasis
0.109 0.891 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.891 0.109
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.891 0.108
E63 Other nutritional deficiencies
0.000 0.891 0.108
E50 Vitamin A deficiency
0.000 0.891 0.108
E60 Dietary zinc deficiency
0.000 0.891 0.108
E59 Dietary selenium deficiency
0.000 0.891 0.108
E52 Niacin deficiency [pellagra]
0.000 0.891 0.108
E16.1 Other hypoglycaemia
0.000 0.892 0.108
E61 Deficiency of other nutrient elements
0.000 0.892 0.108
E58 Dietary calcium deficiency
0.000 0.894 0.106
E53.8 Deficiency of other specified B group vitamins
0.000 0.894 0.106
E56 Other vitamin deficiencies
0.000 0.894 0.106
E54 Ascorbic acid deficiency
0.000 0.894 0.106
E40-E46 Malnutrition
0.000 0.895 0.105
E51 Thiamine deficiency
0.000 0.897 0.103
G63 Polyneuropathy in diseases classified elsewhere
0.103 0.897 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.899 0.101
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.899 0.101
E16.4 Abnormal secretion of gastrin
0.000 0.899 0.101
E16.3 Increased secretion of glucagon
0.000 0.899 0.101
L40.1 Generalised pustular psoriasis
0.100 0.899 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.900 0.100
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.900 0.099
M06.38 Rheumatoid nodule (Other)
0.000 0.900 0.099
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.900 0.099
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.900 0.099
M06.33 Rheumatoid nodule (Forearm)
0.000 0.900 0.099
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.900 0.099
E55.0 Rickets, active
0.000 0.900 0.099
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.901 0.099
G82.3 Flaccid tetraplegia
0.099 0.901 0.000
G82.0 Flaccid paraplegia
0.099 0.901 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.902 0.098
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.902 0.098
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.902 0.098
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.902 0.098
G70.9 Myoneural disorder, unspecified
0.098 0.902 0.000
G80.2 Infantile hemiplegia
0.097 0.903 0.000
G80.8 Other infantile cerebral palsy
0.097 0.903 0.000
G70.8 Other specified myoneural disorders
0.097 0.903 0.000
G70.2 Congenital and developmental myasthenia
0.097 0.903 0.000
G70.1 Toxic myoneural disorders
0.097 0.903 0.000
G82.5 Tetraplegia, unspecified
0.096 0.904 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.093 0.907 0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.907 0.092
E61.1 Iron deficiency
0.000 0.908 0.092
G72 Other myopathies
0.091 0.908 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.909 0.091
G83 Other paralytic syndromes
0.091 0.909 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.910 0.090
G71.9 Primary disorder of muscle, unspecified
0.089 0.910 0.000
G71.8 Other primary disorders of muscles
0.089 0.910 0.000
G71.2 Congenital myopathies
0.089 0.910 0.000
E53.1 Pyridoxine deficiency
0.000 0.911 0.089
E53.0 Riboflavin deficiency
0.000 0.911 0.089
G71.0 Muscular dystrophy
0.089 0.911 0.000
G61 Inflammatory polyneuropathy
0.088 0.911 0.001
E53.9 Vitamin B deficiency, unspecified
0.000 0.912 0.088
G80.4 Ataxic cerebral palsy
0.087 0.913 0.000
G80.3 Dyskinetic cerebral palsy
0.087 0.913 0.000
G00.1 Pneumococcal meningitis
0.086 0.913 0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.914 0.086
E00 Congenital iodine-deficiency syndrome
0.000 0.914 0.086
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.915 0.085
G80.0 Spastic cerebral palsy
0.082 0.917 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.918 0.082
E03.5 Myxoedema coma
0.000 0.918 0.082
E03.4 Atrophy of thyroid (acquired)
0.000 0.918 0.082
E03.3 Postinfectious hypothyroidism
0.000 0.918 0.082
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.918 0.082
M06.34 Rheumatoid nodule (Hand)
0.000 0.918 0.082
E05.9 Thyrotoxicosis, unspecified
0.000 0.919 0.081
E03.8 Other specified hypothyroidism
0.000 0.919 0.081
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.080 0.919 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.920 0.080
G81 Hemiplegia
0.080 0.920 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.079 0.920 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.922 0.078
E50.8 Other manifestations of vitamin A deficiency
0.000 0.922 0.078
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.922 0.078
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.922 0.078
E50.5 Vitamin A deficiency with night blindness
0.000 0.922 0.078
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.922 0.078
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.922 0.078
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.922 0.078
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.922 0.078
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.922 0.078
E63.9 Nutritional deficiency, unspecified
0.000 0.922 0.078
E63.8 Other specified nutritional deficiencies
0.000 0.922 0.078
E63.1 Imbalance of constituents of food intake
0.000 0.922 0.078
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.922 0.078
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.922 0.078
E64.8 Sequelae of other nutritional deficiencies
0.000 0.922 0.078
E64.3 Sequelae of rickets
0.000 0.922 0.078
E64.2 Sequelae of vitamin C deficiency
0.000 0.922 0.078
E64.1 Sequelae of vitamin A deficiency
0.000 0.922 0.078
E64.0 Sequelae of protein-energy malnutrition
0.000 0.922 0.078
G40-G47 Episodic and paroxysmal disorders
0.078 0.922 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.922 0.078
E61.8 Deficiency of other specified nutrient elements
0.000 0.922 0.078
E61.7 Deficiency of multiple nutrient elements
0.000 0.922 0.078
E61.6 Vanadium deficiency
0.000 0.922 0.078
E61.5 Molybdenum deficiency
0.000 0.922 0.078
E61.4 Chromium deficiency
0.000 0.922 0.078
E61.3 Manganese deficiency
0.000 0.922 0.078
E61.0 Copper deficiency
0.000 0.922 0.078
E07 Other disorders of thyroid
0.000 0.923 0.077
G82.4 Spastic tetraplegia
0.076 0.924 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.924 0.076
E56.8 Deficiency of other vitamins
0.000 0.924 0.076
E56.0 Deficiency of vitamin E
0.000 0.924 0.076
G80.1 Spastic diplegia
0.076 0.924 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.924 0.075
E45 Retarded development following protein-energy malnutrition
0.000 0.924 0.075
E43 Unspecified severe protein-energy malnutrition
0.000 0.924 0.075
E42 Marasmic kwashiorkor
0.000 0.924 0.075
E41 Nutritional marasmus
0.000 0.924 0.075
E40 Kwashiorkor
0.000 0.924 0.075
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.926 0.074
E51.9 Thiamine deficiency, unspecified
0.000 0.926 0.074
E51.8 Other manifestations of thiamine deficiency
0.000 0.926 0.074
E51.1 Beriberi
0.000 0.926 0.074
G00.9 Bacterial meningitis, unspecified
0.074 0.926 0.001
G63.8 Polyneuropathy in other diseases classified elsewhere
0.074 0.926 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.074 0.926 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.074 0.926 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.074 0.926 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.074 0.926 0.000
G63.1 Polyneuropathy in neoplastic disease
0.074 0.926 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.074 0.926 0.000
E56.1 Deficiency of vitamin K
0.000 0.926 0.073
G70.0 Myasthenia gravis
0.073 0.927 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.927 0.073
G71.1 Myotonic disorders
0.072 0.927 0.000
G62 Other polyneuropathies
0.072 0.928 0.000
E83.4 Disorders of magnesium metabolism
0.071 0.928 0.000
L40.0 Psoriasis vulgaris
0.070 0.930 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.070 0.930 0.001
G83.3 Monoplegia, unspecified
0.069 0.931 0.000
G41 Status epilepticus
0.069 0.931 0.000
E51.2 Wernicke's encephalopathy
0.000 0.931 0.069
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.931 0.069
G72.4 Inflammatory myopathy, not elsewhere classified
0.068 0.931 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.931 0.068
G83.1 Monoplegia of lower limb
0.068 0.932 0.000
E06 Thyroiditis
0.000 0.932 0.068
G90-G99 Other disorders of the nervous system
0.068 0.932 0.000
G83.2 Monoplegia of upper limb
0.067 0.933 0.000
G72.3 Periodic paralysis
0.065 0.934 0.000
G72.2 Myopathy due to other toxic agents
0.065 0.934 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.066 0.934 0.000
G83.5 Locked-in syndrome
0.065 0.935 0.000
G83.0 Diplegia of upper limbs
0.065 0.935 0.000
G82.2 Paraplegia, unspecified
0.065 0.935 0.000
E05.5 Thyroid crisis or storm
0.000 0.935 0.065
E05.4 Thyrotoxicosis factitia
0.000 0.935 0.065
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.935 0.065
G61.1 Serum neuropathy
0.063 0.936 0.001
E05.8 Other thyrotoxicosis
0.000 0.937 0.063
E07.8 Other specified disorders of thyroid
0.000 0.937 0.063
G72.8 Other specified myopathies
0.062 0.937 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.938 0.062
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.938 0.062
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.938 0.062
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.938 0.062
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.938 0.062
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.938 0.062
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.938 0.062
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.938 0.062
G72.1 Alcoholic myopathy
0.061 0.938 0.001
G46.7 Other lacunar syndromes
0.061 0.939 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.939 0.061
E46 Unspecified protein-energy malnutrition
0.000 0.939 0.061
G41.9 Status epilepticus, unspecified
0.060 0.940 0.000
G81.0 Flaccid hemiplegia
0.057 0.942 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.057 0.943 0.000
G81.1 Spastic hemiplegia
0.057 0.943 0.000
G80.9 Infantile cerebral palsy, unspecified
0.056 0.943 0.000
G31.8 Other specified degenerative diseases of nervous system
0.056 0.944 0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.944 0.056
E07.1 Dyshormogenetic goitre
0.000 0.945 0.055
E07.0 Hypersecretion of calcitonin
0.000 0.945 0.055
E44.1 Mild protein-energy malnutrition
0.000 0.946 0.054
E44.0 Moderate protein-energy malnutrition
0.000 0.946 0.054
G96 Other disorders of central nervous system
0.054 0.946 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.946 0.054
L40-L45 Papulosquamous disorders
0.054 0.946 0.000
G83.9 Paralytic syndrome, unspecified
0.053 0.946 0.000
G72.9 Myopathy, unspecified
0.053 0.946 0.000
G41.0 Grand mal status epilepticus
0.053 0.947 0.000
E06.5 Other chronic thyroiditis
0.000 0.947 0.053
G62.8 Other specified polyneuropathies
0.053 0.947 0.000
G62.2 Polyneuropathy due to other toxic agents
0.052 0.948 0.000
G41.2 Complex partial status epilepticus
0.052 0.948 0.000
G61.8 Other inflammatory polyneuropathies
0.051 0.948 0.001
E61.2 Magnesium deficiency
0.001 0.948 0.051
G41.8 Other status epilepticus
0.050 0.950 0.000
G41.1 Petit mal status epilepticus
0.050 0.950 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.049 0.951 0.000
E06.4 Drug-induced thyroiditis
0.000 0.951 0.049
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.951 0.049
E06.1 Subacute thyroiditis
0.000 0.951 0.049
E06.0 Acute thyroiditis
0.000 0.951 0.049
G92 Toxic encephalopathy
0.049 0.951 0.000
G83.4 Cauda equina syndrome
0.048 0.952 0.000
G62.1 Alcoholic polyneuropathy
0.048 0.952 0.000
G83.8 Other specified paralytic syndromes
0.047 0.952 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.047 0.953 0.000
G46.6 Pure sensory lacunar syndrome
0.047 0.953 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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