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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28498264
log Bayes Factor = 18.6374
Chromosome 15   position 78,837,673  (GRCh37) Explore rs28498264 on Ensembl!
Variant rs28498264 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.002 0.998
I70 Atherosclerosis
0.000 0.005 0.995
I73 Other peripheral vascular diseases
0.000 0.005 0.995
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.008 0.992
Chapter X Diseases of the respiratory system
0.000 0.010 0.990
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.011 0.989
J90-J94 Other diseases of pleura
0.000 0.014 0.986
I73.9 Peripheral vascular disease, unspecified
0.000 0.016 0.984
J92 Pleural plaque
0.000 0.020 0.980
J42 Unspecified chronic bronchitis
0.000 0.031 0.969
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.042 0.958
J95-J99 Other diseases of the respiratory system
0.000 0.047 0.953
J92.0 Pleural plaque with presence of asbestos
0.000 0.050 0.950
J60-J70 Lung diseases due to external agents
0.000 0.052 0.948
J92.9 Pleural plaque without asbestos
0.000 0.059 0.941
J90 Pleural effusion, not elsewhere classified
0.000 0.065 0.935
J98 Other respiratory disorders
0.000 0.072 0.928
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.080 0.920
J98.1 Pulmonary collapse
0.000 0.084 0.916
I73.0 Raynaud's syndrome
0.000 0.084 0.916
I72 Other aneurysm
0.000 0.087 0.913
I60-I69 Cerebrovascular diseases
0.000 0.089 0.911
Chapter IX Diseases of the circulatory system
0.000 0.092 0.908
I77 Other disorders of arteries and arterioles
0.000 0.100 0.900
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.103 0.897
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.104 0.896
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.109 0.891
I60 Subarachnoid haemorrhage
0.000 0.111 0.889
I67 Other cerebrovascular diseases
0.000 0.114 0.886
I69 Sequelae of cerebrovascular disease
0.000 0.127 0.873
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.140 0.860
I27 Other pulmonary heart diseases
0.000 0.140 0.860
I67.9 Cerebrovascular disease, unspecified
0.000 0.145 0.855
I27.9 Pulmonary heart disease, unspecified
0.000 0.152 0.848
J86 Pyothorax
0.000 0.164 0.836
I26 Pulmonary embolism
0.000 0.166 0.834
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.168 0.832
I69.3 Sequelae of cerebral infarction
0.000 0.172 0.828
I72.0 Aneurysm of carotid artery
0.000 0.174 0.826
J43.2 Centrilobular emphysema
0.000 0.176 0.823
I70.0 Atherosclerosis of aorta
0.000 0.184 0.816
J98.4 Other disorders of lung
0.000 0.188 0.812
I60.8 Other subarachnoid haemorrhage
0.000 0.198 0.802
J98.9 Respiratory disorder, unspecified
0.000 0.201 0.799
J86.9 Pyothorax without fistula
0.000 0.202 0.798
J93 Pneumothorax
0.000 0.212 0.788
I72.8 Aneurysm of other specified arteries
0.000 0.213 0.787
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.214 0.786
I77.0 Arteriovenous fistula, acquired
0.000 0.214 0.786
I67.8 Other specified cerebrovascular diseases
0.000 0.221 0.779
I77.1 Stricture of artery
0.000 0.225 0.775
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.229 0.771
I71.0 Dissection of aorta [any part]
0.000 0.235 0.765
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.236 0.764
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.244 0.756
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.250 0.750
J60 Coalworker's pneumoconiosis
0.000 0.254 0.746
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.254 0.746
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.263 0.737
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.271 0.729
I67.1 Cerebral aneurysm, nonruptured
0.000 0.273 0.727
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.279 0.721
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.286 0.714
I70.9 Generalised and unspecified atherosclerosis
0.000 0.286 0.714
I70.8 Atherosclerosis of other arteries
0.000 0.286 0.714
J93.1 Other spontaneous pneumothorax
0.000 0.286 0.714
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.287 0.713
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.288 0.712
J64 Unspecified pneumoconiosis
0.000 0.296 0.704
I77.2 Rupture of artery
0.000 0.299 0.701
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.304 0.696
I72.9 Aneurysm of unspecified site
0.000 0.305 0.695
I78 Diseases of capillaries
0.000 0.306 0.694
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.313 0.687
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.313 0.687
J96 Respiratory failure, not elsewhere classified
0.000 0.316 0.684
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.320 0.679
J66 Airway disease due to specific organic dust
0.000 0.320 0.679
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.320 0.679
J62 Pneumoconiosis due to dust containing silica
0.000 0.320 0.679
J65 Pneumoconiosis associated with tuberculosis
0.000 0.320 0.679
J98.2 Interstitial emphysema
0.000 0.326 0.674
I61 Intracerebral haemorrhage
0.000 0.331 0.668
J98.3 Compensatory emphysema
0.000 0.334 0.665
J69 Pneumonitis due to solids and liquids
0.000 0.339 0.661
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.345 0.655
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.345 0.655
I72.1 Aneurysm of artery of upper extremity
0.000 0.345 0.655
I72.3 Aneurysm of iliac artery
0.000 0.348 0.652
I28 Other diseases of pulmonary vessels
0.000 0.351 0.649
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.352 0.648
I00-I02 Acute rheumatic fever
0.000 0.354 0.646
I77.5 Necrosis of artery
0.000 0.355 0.645
I77.4 Coeliac artery compression syndrome
0.000 0.355 0.645
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.359 0.641
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.362 0.638
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.363 0.637
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.363 0.637
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.365 0.635
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.365 0.635
I67.5 Moyamoya disease
0.000 0.365 0.635
I67.4 Hypertensive encephalopathy
0.000 0.365 0.635
I67.3 Progressive vascular leukoencephalopathy
0.000 0.365 0.635
I27.8 Other specified pulmonary heart diseases
0.000 0.375 0.625
J70 Respiratory conditions due to other external agents
0.000 0.376 0.624
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.376 0.624
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.383 0.617
I27.1 Kyphoscoliotic heart disease
0.000 0.384 0.616
I73.8 Other specified peripheral vascular diseases
0.000 0.384 0.616
I74 Arterial embolism and thrombosis
0.000 0.387 0.613
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.392 0.608
J43.8 Other emphysema
0.000 0.396 0.604
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.400 0.600
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.403 0.596
I79.1 Aortitis in diseases classified elsewhere
0.000 0.403 0.596
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.403 0.596
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.405 0.595
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.406 0.594
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.408 0.592
I70.1 Atherosclerosis of renal artery
0.000 0.408 0.592
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.409 0.591
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.411 0.589
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.414 0.586
J86.0 Pyothorax with fistula
0.000 0.414 0.586
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.415 0.585
I72.2 Aneurysm of renal artery
0.000 0.418 0.582
J93.0 Spontaneous tension pneumothorax
0.000 0.420 0.579
J40 Bronchitis, not specified as acute or chronic
0.000 0.421 0.579
J98.6 Disorders of diaphragm
0.000 0.424 0.576
J85 Abscess of lung and mediastinum
0.000 0.429 0.571
I72.4 Aneurysm of artery of lower extremity
0.000 0.429 0.571
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.431 0.568
I77.3 Arterial fibromuscular dysplasia
0.000 0.442 0.558
J99.0 Rheumatoid lung disease
0.000 0.443 0.557
J93.8 Other pneumothorax
0.000 0.453 0.547
I27.0 Primary pulmonary hypertension
0.000 0.455 0.545
J94 Other pleural conditions
0.000 0.459 0.540
F17.1 Harmful use
0.000 0.464 0.536
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.466 0.534
I68.0 Cerebral amyloid angiopathy
0.000 0.473 0.526
I77.8 Other specified disorders of arteries and arterioles
0.000 0.478 0.522
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.488 0.512
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.488 0.512
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.488 0.512
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.488 0.512
J69.8 Pneumonitis due to other solids and liquids
0.000 0.492 0.508
J95.8 Other postprocedural respiratory disorders
0.000 0.501 0.499
I78.9 Disease of capillaries, unspecified
0.000 0.502 0.498
J09-J18 Influenza and pneumonia
0.000 0.504 0.496
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.507 0.493
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.507 0.493
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.507 0.493
J96.9 Respiratory failure, unspecified
0.000 0.510 0.490
J96.1 Chronic respiratory failure
0.000 0.510 0.490
J96.0 Acute respiratory failure
0.000 0.510 0.490
I77.6 Arteritis, unspecified
0.000 0.510 0.489
I67.2 Cerebral atherosclerosis
0.000 0.511 0.489
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.513 0.487
J62.0 Pneumoconiosis due to talc dust
0.000 0.513 0.487
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.513 0.487
J63.5 Stannosis
0.000 0.513 0.487
J63.4 Siderosis
0.000 0.513 0.487
J63.3 Graphite fibrosis (of lung)
0.000 0.513 0.487
J63.2 Berylliosis
0.000 0.513 0.487
J63.1 Bauxite fibrosis (of lung)
0.000 0.513 0.487
J63.0 Aluminosis (of lung)
0.000 0.513 0.487
J66.8 Airway disease due to other specific organic dusts
0.000 0.513 0.487
J66.2 Cannabinosis
0.000 0.513 0.487
J66.1 Flax-dresser's disease
0.000 0.513 0.487
J66.0 Byssinosis
0.000 0.513 0.487
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.513 0.487
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.513 0.487
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.513 0.487
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.513 0.487
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.513 0.487
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.513 0.487
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.513 0.487
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.521 0.479
I62 Other nontraumatic intracranial haemorrhage
0.000 0.524 0.476
J69.1 Pneumonitis due to oils and essences
0.000 0.526 0.474
I78.8 Other diseases of capillaries
0.000 0.527 0.473
I28.8 Other specified diseases of pulmonary vessels
0.000 0.529 0.471
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.535 0.465
I28.1 Aneurysm of pulmonary artery
0.000 0.535 0.465
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.535 0.465
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.535 0.465
I02 Rheumatic chorea
0.000 0.537 0.463
I01 Rheumatic fever with heart involvement
0.000 0.537 0.463
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.537 0.463
I00 Rheumatic fever without mention of heart involvement
0.000 0.542 0.458
J46 Status asthmaticus
0.000 0.544 0.456
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.546 0.454
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.547 0.453
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.551 0.449
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.552 0.448
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.553 0.447
J70.8 Respiratory conditions due to other specified external agents
0.000 0.553 0.447
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.553 0.447
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.553 0.447
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.553 0.447
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.553 0.447
J95.5 Postprocedural subglottic stenosis
0.000 0.553 0.447
J95.4 Mendelson's syndrome
0.000 0.553 0.447
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.553 0.447
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.553 0.447
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.553 0.447
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.557 0.443
J67.7 Air-conditioner and humidifier lung
0.000 0.557 0.443
J67.6 Maple-bark-stripper's lung
0.000 0.557 0.443
J67.5 Mushroom-worker's lung
0.000 0.557 0.443
J67.4 Maltworker's lung
0.000 0.557 0.443
J67.3 Suberosis
0.000 0.557 0.443
J67.1 Bagassosis
0.000 0.557 0.443
J67.0 Farmer's lung
0.000 0.557 0.443
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.560 0.439
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.560 0.439
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.562 0.437
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.564 0.436
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.564 0.436
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.564 0.436
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.564 0.436
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.565 0.435
F17.2 Dependence syndrome
0.000 0.565 0.435
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.567 0.433
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.568 0.432
I27.2 Other secondary pulmonary hypertension
0.000 0.569 0.431
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.572 0.428
I74.8 Embolism and thrombosis of other arteries
0.000 0.574 0.426
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.574 0.426
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.575 0.424
J91 Pleural effusion in conditions classified elsewhere
0.000 0.576 0.423
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.578 0.421
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.581 0.419
J18 Pneumonia, organism unspecified
0.000 0.585 0.415
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.588 0.412
J69.0 Pneumonitis due to food and vomit
0.000 0.590 0.410
I05-I09 Chronic rheumatic heart diseases
0.000 0.590 0.410
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.590 0.409
J85.3 Abscess of mediastinum
0.000 0.590 0.409
J85.0 Gangrene and necrosis of lung
0.000 0.590 0.409
J85.1 Abscess of lung with pneumonia
0.000 0.592 0.408
J67.2 Bird fancier's lung
0.000 0.594 0.406
J18.1 Lobar pneumonia, unspecified
0.000 0.594 0.406
J98.8 Other specified respiratory disorders
0.000 0.598 0.401
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.599 0.400
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.602 0.398
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.602 0.398
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.608 0.391
J94.9 Pleural condition, unspecified
0.000 0.612 0.387
J94.0 Chylous effusion
0.000 0.612 0.387
J94.8 Other specified pleural conditions
0.000 0.613 0.387
I74.5 Embolism and thrombosis of iliac artery
0.000 0.615 0.385
J94.1 Fibrothorax
0.000 0.617 0.383
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.617 0.383
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.624 0.375
J10 Influenza due to identified influenza virus
0.000 0.631 0.369
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.636 0.364
J95.0 Tracheostomy malfunction
0.000 0.636 0.364
J93.9 Pneumothorax, unspecified
0.000 0.636 0.364
I61.8 Other intracerebral haemorrhage
0.000 0.640 0.360
J20-J22 Other acute lower respiratory infections
0.000 0.643 0.357
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.644 0.356
J09 Influenza due to certain identified influenza virus
0.000 0.644 0.356
J96.09 Acute respiratory failure; Type unspecified
0.000 0.648 0.351
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.648 0.351
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.648 0.351
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.648 0.351
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.648 0.351
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.648 0.351
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.648 0.351
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.648 0.351
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.648 0.351
J85.2 Abscess of lung without pneumonia
0.000 0.656 0.344
I78.1 Naevus, nonneoplastic
0.000 0.656 0.344
J17 Pneumonia in diseases classified elsewhere
0.000 0.657 0.343
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.657 0.343
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.668 0.332
I01.8 Other acute rheumatic heart disease
0.000 0.668 0.332
I01.2 Acute rheumatic myocarditis
0.000 0.668 0.332
I01.1 Acute rheumatic endocarditis
0.000 0.668 0.332
I01.0 Acute rheumatic pericarditis
0.000 0.668 0.332
I02.9 Rheumatic chorea without heart involvement
0.000 0.668 0.332
I02.0 Rheumatic chorea with heart involvement
0.000 0.668 0.332
I09 Other rheumatic heart diseases
0.000 0.673 0.327
F17.9 Unspecified mental and behavioural disorder
0.000 0.675 0.325
F17.8 Other mental and behavioural disorders
0.000 0.675 0.325
F17.7 Residual and late-onset psychotic disorder
0.000 0.675 0.325
F17.6 Amnesic syndrome
0.000 0.675 0.325
F17.5 Psychotic disorder
0.000 0.675 0.325
F17.4 Withdrawal state with delirium
0.000 0.675 0.325
F17.3 Withdrawal state
0.000 0.675 0.325
F17.0 Acute intoxication
0.000 0.675 0.325
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.682 0.318
J12 Viral pneumonia, not elsewhere classified
0.000 0.683 0.317
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.691 0.309
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.691 0.309
I62.1 Nontraumatic extradural haemorrhage
0.000 0.694 0.305
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.697 0.302
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.702 0.298
J18.2 Hypostatic pneumonia, unspecified
0.000 0.702 0.298
J00-J06 Acute upper respiratory infections
0.000 0.708 0.292
I07 Rheumatic tricuspid valve diseases
0.000 0.709 0.291
J14 Pneumonia due to Haemophilus influenzae
0.000 0.709 0.290
I05 Rheumatic mitral valve diseases
0.000 0.718 0.282
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.719 0.280
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.720 0.280
I06 Rheumatic aortic valve diseases
0.000 0.721 0.278
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.731 0.269
I09.9 Rheumatic heart disease, unspecified
0.000 0.732 0.268
J18.8 Other pneumonia, organism unspecified
0.000 0.732 0.268
I99 Other and unspecified disorders of circulatory system
0.000 0.734 0.266
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.735 0.264
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.739 0.261
J45 Asthma
0.000 0.740 0.260
I95 Hypotension
0.000 0.741 0.259
J84 Other interstitial pulmonary diseases
0.000 0.743 0.257
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.745 0.255
J16.0 Chlamydial pneumonia
0.000 0.745 0.255
J15.8 Other bacterial pneumonia
0.000 0.751 0.249
J15.2 Pneumonia due to staphylococcus
0.000 0.751 0.249
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.754 0.246
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.754 0.246
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.754 0.246
I98.0 Cardiovascular syphilis
0.000 0.754 0.246
J21 Acute bronchiolitis
0.000 0.757 0.243
J15.5 Pneumonia due to Escherichia coli
0.000 0.762 0.238
I05.1 Rheumatic mitral insufficiency
0.000 0.765 0.235
I09.8 Other specified rheumatic heart diseases
0.000 0.765 0.235
I09.2 Chronic rheumatic pericarditis
0.000 0.765 0.235
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.765 0.235
I09.0 Rheumatic myocarditis
0.000 0.765 0.235
J20 Acute bronchitis
0.000 0.768 0.232
J94.2 Haemothorax
0.001 0.769 0.230
I95.1 Orthostatic hypotension
0.000 0.770 0.230
J15.4 Pneumonia due to other streptococci
0.000 0.770 0.230
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.772 0.228
J15.3 Pneumonia due to streptococcus, group B
0.000 0.772 0.228
J12.8 Other viral pneumonia
0.000 0.772 0.227
J12.3 Human metapneumovirus pneumonia
0.000 0.772 0.227
J12.2 Parainfluenza virus pneumonia
0.000 0.772 0.227
J12.1 Respiratory syncytial virus pneumonia
0.000 0.772 0.227
J12.0 Adenoviral pneumonia
0.000 0.772 0.227
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.775 0.225
J00 Acute nasopharyngitis [common cold]
0.000 0.776 0.224
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.777 0.223
J15.9 Bacterial pneumonia, unspecified
0.000 0.777 0.223
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.778 0.222
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.778 0.222
J11 Influenza, virus not identified
0.001 0.780 0.220
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.781 0.219
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.782 0.218
I95.8 Other hypotension
0.000 0.790 0.210
I07.9 Tricuspid valve disease, unspecified
0.000 0.791 0.209
I07.8 Other tricuspid valve diseases
0.000 0.791 0.209
I07.2 Tricuspid stenosis with insufficiency
0.000 0.791 0.209
I07.0 Tricuspid stenosis
0.000 0.791 0.209
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.791 0.209
I07.1 Tricuspid insufficiency
0.000 0.794 0.206
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.794 0.206
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.794 0.205
J17.3 Pneumonia in parasitic diseases
0.000 0.795 0.204
I05.0 Mitral stenosis
0.000 0.796 0.204
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.797 0.202
I05.8 Other mitral valve diseases
0.000 0.798 0.202
J18.9 Pneumonia, unspecified
0.000 0.799 0.201
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.800 0.200
I06.8 Other rheumatic aortic valve diseases
0.000 0.800 0.200
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.800 0.200
I06.1 Rheumatic aortic insufficiency
0.000 0.800 0.200
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.801 0.199
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.801 0.199
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.807 0.193
I97.0 Postcardiotomy syndrome
0.000 0.807 0.193
I63 Cerebral infarction
0.000 0.808 0.192
Z72.0 Tobacco use
0.000 0.809 0.191
I10-I15 Hypertensive diseases
0.000 0.809 0.191
J12.9 Viral pneumonia, unspecified
0.000 0.811 0.188
J01 Acute sinusitis
0.000 0.812 0.188
J45.8 Mixed asthma
0.000 0.813 0.187
J45.1 Nonallergic asthma
0.000 0.813 0.187
Z72 Problems related to lifestyle
0.000 0.813 0.187
Z72.1 Alcohol use
0.000 0.814 0.186
J84.0 Alveolar and parietoalveolar conditions
0.000 0.815 0.185
I06.0 Rheumatic aortic stenosis
0.000 0.815 0.184
I05.2 Mitral stenosis with insufficiency
0.000 0.820 0.180
J84.8 Other specified interstitial pulmonary diseases
0.000 0.820 0.180
J15.1 Pneumonia due to Pseudomonas
0.000 0.821 0.179
J17.2 Pneumonia in mycoses
0.001 0.823 0.176
J05.1 Acute epiglottitis
0.000 0.824 0.176
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.825 0.174
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.825 0.174
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.825 0.174
J04 Acute laryngitis and tracheitis
0.000 0.827 0.173
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.833 0.167
J20.7 Acute bronchitis due to echovirus
0.000 0.833 0.167
J20.6 Acute bronchitis due to rhinovirus
0.000 0.833 0.167
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.833 0.167
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.833 0.167
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.833 0.167
J20.2 Acute bronchitis due to streptococcus
0.000 0.833 0.167
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.833 0.167
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.833 0.167
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.834 0.166
J20.8 Acute bronchitis due to other specified organisms
0.000 0.836 0.164
J21.9 Acute bronchiolitis, unspecified
0.000 0.838 0.161
J02 Acute pharyngitis
0.000 0.839 0.161
J05.0 Acute obstructive laryngitis [croup]
0.000 0.839 0.161
I65.1 Occlusion and stenosis of basilar artery
0.001 0.840 0.160
I95.0 Idiopathic hypotension
0.000 0.841 0.159
J11.8 Influenza with other manifestations, virus not identified
0.001 0.842 0.158
J03 Acute tonsillitis
0.000 0.843 0.157
I05.9 Mitral valve disease, unspecified
0.000 0.845 0.155
Z72.2 Drug use
0.000 0.846 0.154
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.852 0.147
I97.1 Other functional disturbances following cardiac surgery
0.000 0.854 0.146
J20.9 Acute bronchitis, unspecified
0.000 0.854 0.146
I65.2 Occlusion and stenosis of carotid artery
0.000 0.855 0.145
J01.0 Acute maxillary sinusitis
0.000 0.859 0.141
J47 Bronchiectasis
0.000 0.861 0.139
Z72.4 Inappropriate diet and eating habits
0.000 0.862 0.138
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.862 0.138
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.862 0.138
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.862 0.138
I13 Hypertensive heart and renal disease
0.000 0.863 0.137
I15 Secondary hypertension
0.000 0.864 0.136
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.864 0.135
J01.8 Other acute sinusitis
0.000 0.865 0.135
J01.4 Acute pansinusitis
0.000 0.865 0.135
J01.3 Acute sphenoidal sinusitis
0.000 0.865 0.135
J01.1 Acute frontal sinusitis
0.000 0.865 0.135
Z72.6 Gambling and betting
0.000 0.866 0.134
Z72.5 High-risk sexual behaviour
0.000 0.866 0.134
Z72.3 Lack of physical exercise
0.000 0.866 0.134
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.868 0.132
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.869 0.131
Z72.8 Other problems related to lifestyle
0.000 0.869 0.131
J81 Pulmonary oedema
0.000 0.872 0.128
J18.0 Bronchopneumonia, unspecified
0.000 0.872 0.128
J01.2 Acute ethmoidal sinusitis
0.000 0.872 0.127
J11.0 Influenza with pneumonia, virus not identified
0.001 0.876 0.124
J04.2 Acute laryngotracheitis
0.000 0.876 0.124
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.878 0.122
Z72.9 Problem related to lifestyle, unspecified
0.000 0.878 0.121
J02.0 Streptococcal pharyngitis
0.000 0.881 0.119
J04.1 Acute tracheitis
0.000 0.881 0.118
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.884 0.116
I87 Other disorders of veins
0.000 0.885 0.115
J01.9 Acute sinusitis, unspecified
0.000 0.885 0.115
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.887 0.112
J03.0 Streptococcal tonsillitis
0.000 0.887 0.112
J45.0 Predominantly allergic asthma
0.000 0.890 0.110
I15.1 Hypertension secondary to other renal disorders
0.000 0.893 0.107
I85 Oesophageal varices
0.000 0.893 0.107
I88 Nonspecific lymphadenitis
0.000 0.895 0.105
I87.1 Compression of vein
0.000 0.896 0.104
I81 Portal vein thrombosis
0.000 0.896 0.103
I12 Hypertensive renal disease
0.000 0.897 0.103
I11 Hypertensive heart disease
0.000 0.898 0.101
I95.9 Hypotension, unspecified
0.000 0.899 0.101
I15.9 Seconday hypertension, unspecified
0.000 0.901 0.099
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.902 0.098
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.902 0.098
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.902 0.098
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.902 0.098
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.902 0.097
C34.1 Upper lobe, bronchus or lung
0.000 0.902 0.098
I15.8 Other secondary hypertension
0.000 0.902 0.097
I15.2 Hypertension secondary to endocrine disorders
0.000 0.902 0.097
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.903 0.097
J04.0 Acute laryngitis
0.000 0.904 0.096
I87.8 Other specified disorders of veins
0.000 0.905 0.095
I85.0 Oesophageal varices with bleeding
0.000 0.905 0.095
Z70-Z76 Persons encountering health services in other circumstances
0.000 0.907 0.093
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.908 0.092
C34 Malignant neoplasm of bronchus and lung
0.000 0.909 0.091
I80 Phlebitis and thrombophlebitis
0.000 0.909 0.091
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.911 0.089
C34.3 Lower lobe, bronchus or lung
0.000 0.913 0.087
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.914 0.086
C34.9 Bronchus or lung, unspecified
0.000 0.916 0.084
J80 Adult respiratory distress syndrome
0.001 0.916 0.082

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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