TreeWAS – Variant ID: rs2853929

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40 Psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.105	0.894
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
L40.1 Generalised pustular psoriasis	0.000	0.284	0.716
L40.8 Other psoriasis	0.000	0.331	0.669
E03 Other hypothyroidism	0.561	0.439	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.479	0.521	0.000
K90 Intestinal malabsorption	0.000	0.548	0.452
E03.5 Myxoedema coma	0.402	0.597	0.001
E03.4 Atrophy of thyroid (acquired)	0.402	0.597	0.001
E03.3 Postinfectious hypothyroidism	0.402	0.597	0.001
E03.1 Congenital hypothyroidism without goitre	0.402	0.597	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.402	0.597	0.001
E03.8 Other specified hypothyroidism	0.377	0.622	0.001
L40-L45 Papulosquamous disorders	0.000	0.633	0.367
K90.9 Intestinal malabsorption, unspecified	0.000	0.644	0.356
K90.3 Pancreatic steatorrhoea	0.000	0.676	0.324
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.676	0.324
K90.1 Tropical sprue	0.000	0.676	0.324
K90.8 Other intestinal malabsorption	0.000	0.682	0.318
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.702	0.298
L44 Other papulosquamous disorders	0.000	0.737	0.263
L41 Parapsoriasis	0.000	0.737	0.263
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.737	0.263
L43 Lichen planus	0.000	0.748	0.252
L42 Pityriasis rosea	0.000	0.750	0.250
L43.8 Other lichen planus	0.000	0.810	0.190
L41.9 Parapsoriasis, unspecified	0.000	0.811	0.189
L41.8 Other parapsoriasis	0.000	0.811	0.189
L41.5 Retiform parapsoriasis	0.000	0.811	0.189
L41.4 Large plaque parapsoriasis	0.000	0.811	0.189
L41.3 Small plaque parapsoriasis	0.000	0.811	0.189
L41.2 Lymphomatoid papulosis	0.000	0.811	0.189
L41.1 Pityriasis lichenoides chronica	0.000	0.811	0.189
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.811	0.189
L44.9 Papulosquamous disorder, unspecified	0.000	0.811	0.189
L44.8 Other specified papulosquamous disorders	0.000	0.811	0.189
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.811	0.189
L44.3 Lichen ruber moniliformis	0.000	0.811	0.189
L44.2 Lichen striatus	0.000	0.811	0.189
L44.1 Lichen nitidus	0.000	0.811	0.189
L44.0 Pityriasis rubra pilaris	0.000	0.811	0.189
L43.3 Subacute (active) lichen planus	0.000	0.819	0.181
L43.2 Lichenoid drug reaction	0.000	0.819	0.181
L43.1 Bullous lichen planus	0.000	0.819	0.181
L43.0 Hypertrophic lichen planus	0.000	0.819	0.181
L43.9 Lichen planus, unspecified	0.000	0.843	0.157
M25.5 Pain in joint	0.000	0.860	0.140
M25.54 Pain in joint (Hand)	0.000	0.864	0.136
M25.51 Pain in joint (Shoulder region)	0.000	0.865	0.135
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.873	0.127
M25.59 Pain in joint (Site unspecified)	0.000	0.877	0.123
M25.58 Pain in joint (Other)	0.000	0.886	0.114
M25.56 Pain in joint (Lower leg)	0.000	0.898	0.102
M25 Other joint disorders, not elsewhere classified	0.000	0.898	0.102
M25.57 Pain in joint (Ankle and foot)	0.000	0.904	0.096
I84.9 Unspecified haemorrhoids without complication	0.094	0.906	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.906	0.094
M25.9 Joint disorder, unspecified	0.000	0.908	0.092
M25.53 Pain in joint (Forearm)	0.000	0.909	0.091
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.911	0.089
M25.52 Pain in joint (Upper arm)	0.000	0.913	0.087
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.915	0.085
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.916	0.084
M25.7 Osteophyte	0.000	0.919	0.081
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.925	0.075
M25.2 Flail joint	0.000	0.927	0.073
M25.1 Fistula of joint	0.000	0.927	0.073
M25.8 Other specified joint disorders	0.000	0.928	0.072
M25.0 Haemarthrosis	0.000	0.930	0.069
M25.74 Osteophyte (Hand)	0.000	0.932	0.068
M25.77 Osteophyte (Ankle and foot)	0.000	0.932	0.068
M25.71 Osteophyte (Shoulder region)	0.000	0.933	0.067
M25.84 Other specified joint disorders (Hand)	0.000	0.933	0.067
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.934	0.066
M25.98 Joint disorder, unspecified (Other)	0.000	0.934	0.066
M25.94 Joint disorder, unspecified (Hand)	0.000	0.934	0.066
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.934	0.066
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.934	0.066
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.934	0.066
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.934	0.066
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.935	0.065
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.935	0.065
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.936	0.064
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.936	0.064
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.936	0.064
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.937	0.063
M25.3 Other instability of joint	0.000	0.939	0.061
M25.76 Osteophyte (Lower leg)	0.000	0.940	0.060
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.940	0.060
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.941	0.058
M25.79 Osteophyte (Site unspecified)	0.000	0.942	0.058
M25.73 Osteophyte (Forearm)	0.000	0.942	0.058
M25.70 Osteophyte (Multiple sites)	0.000	0.942	0.058
M25.72 Osteophyte (Upper arm)	0.000	0.942	0.058
M25.86 Other specified joint disorders (Lower leg)	0.000	0.943	0.057
M25.4 Effusion of joint	0.000	0.944	0.056
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.947	0.053
M25.19 Fistula of joint (Site unspecified)	0.000	0.947	0.053
M25.18 Fistula of joint (Other)	0.000	0.947	0.053
M25.17 Fistula of joint (Ankle and foot)	0.000	0.947	0.053
M25.16 Fistula of joint (Lower leg)	0.000	0.947	0.053
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.947	0.053
M25.14 Fistula of joint (Hand)	0.000	0.947	0.053
M25.13 Fistula of joint (Forearm)	0.000	0.947	0.053
M25.12 Fistula of joint (Upper arm)	0.000	0.947	0.053
M25.11 Fistula of joint (Shoulder region)	0.000	0.947	0.053
M25.10 Fistula of joint (Multiple sites)	0.000	0.947	0.053
M25.29 Flail joint (Site unspecified)	0.000	0.947	0.053
M25.28 Flail joint (Other)	0.000	0.947	0.053
M25.27 Flail joint (Ankle and foot)	0.000	0.947	0.053
M25.26 Flail joint (Lower leg)	0.000	0.947	0.053
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.947	0.053
M25.24 Flail joint (Hand)	0.000	0.947	0.053
M25.23 Flail joint (Forearm)	0.000	0.947	0.053
M25.22 Flail joint (Upper arm)	0.000	0.947	0.053
M25.21 Flail joint (Shoulder region)	0.000	0.947	0.053
M25.20 Flail joint (Multiple sites)	0.000	0.947	0.053
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.948	0.052
M25.82 Other specified joint disorders (Upper arm)	0.000	0.948	0.052
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.948	0.052
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.949	0.051
M25.09 Haemarthrosis (Site unspecified)	0.000	0.950	0.050
M25.08 Haemarthrosis (Other)	0.000	0.950	0.050
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.950	0.050
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.950	0.050
M25.04 Haemarthrosis (Hand)	0.000	0.950	0.050
M25.03 Haemarthrosis (Forearm)	0.000	0.950	0.050
M25.02 Haemarthrosis (Upper arm)	0.000	0.950	0.050
M25.01 Haemarthrosis (Shoulder region)	0.000	0.950	0.050
M25.00 Haemarthrosis (Multiple sites)	0.000	0.950	0.050
M25.46 Effusion of joint (Lower leg)	0.000	0.951	0.049
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.952	0.048
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.953	0.047
M25.06 Haemarthrosis (Lower leg)	0.000	0.954	0.046
M25.37 Other instability of joint (Ankle and foot)	0.000	0.954	0.046
M25.83 Other specified joint disorders (Forearm)	0.000	0.954	0.046
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.955	0.045
M25.36 Other instability of joint (Lower leg)	0.000	0.956	0.044
M25.43 Effusion of joint (Forearm)	0.000	0.956	0.044
M25.39 Other instability of joint (Site unspecified)	0.000	0.956	0.044
M25.38 Other instability of joint (Other)	0.000	0.956	0.044
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.956	0.044
M25.32 Other instability of joint (Upper arm)	0.000	0.956	0.044
M25.30 Other instability of joint (Multiple sites)	0.000	0.956	0.044
M25.88 Other specified joint disorders (Other)	0.000	0.958	0.041
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.959	0.041
M25.49 Effusion of joint (Site unspecified)	0.000	0.959	0.041
M25.48 Effusion of joint (Other)	0.000	0.959	0.041
M25.41 Effusion of joint (Shoulder region)	0.000	0.959	0.041
M25.31 Other instability of joint (Shoulder region)	0.000	0.960	0.040
M25.34 Other instability of joint (Hand)	0.000	0.961	0.039
M25.33 Other instability of joint (Forearm)	0.000	0.961	0.038
E00-E07 Disorders of thyroid gland	0.034	0.962	0.004
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.963	0.037
M25.42 Effusion of joint (Upper arm)	0.000	0.964	0.036
K90-K93 Other diseases of the digestive system	0.000	0.964	0.036
M25.44 Effusion of joint (Hand)	0.000	0.965	0.035
M25.40 Effusion of joint (Multiple sites)	0.000	0.965	0.034
M25.78 Osteophyte (Other)	0.000	0.968	0.032
E07 Other disorders of thyroid	0.028	0.970	0.002
D12.8 Rectum	0.028	0.972	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.024	0.972	0.003
E00 Congenital iodine-deficiency syndrome	0.024	0.972	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.024	0.972	0.003
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.974	0.026
E07.9 Disorder of thyroid, unspecified	0.025	0.974	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.975	0.025
D75 Other diseases of blood and blood-forming organs	0.000	0.976	0.024
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.976	0.024
S64.4 Injury of digital nerve of other finger	0.024	0.976	0.000
D70 Agranulocytosis	0.000	0.977	0.023
E07.1 Dyshormogenetic goitre	0.020	0.978	0.002
E07.0 Hypersecretion of calcitonin	0.020	0.978	0.002
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.978	0.022
D75.2 Essential thrombocytosis	0.000	0.979	0.021
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.979	0.021
D72 Other disorders of white blood cells	0.000	0.979	0.021
D73 Diseases of spleen	0.000	0.979	0.021
D75.1 Secondary polycythaemia	0.000	0.980	0.020
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.018	0.980	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.018	0.980	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.018	0.980	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.018	0.980	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.018	0.980	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.018	0.980	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.018	0.980	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.018	0.980	0.002
E07.8 Other specified disorders of thyroid	0.018	0.980	0.002
D72.8 Other specified disorders of white blood cells	0.000	0.981	0.019
D73.0 Hyposplenism	0.000	0.981	0.019
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.981	0.019
K93.1 Megacolon in Chagas' disease	0.000	0.981	0.019
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.981	0.019
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.982	0.018
S64 Injury of nerves at wrist and hand level	0.018	0.982	0.000
E06 Thyroiditis	0.014	0.982	0.004
D74 Methaemoglobinaemia	0.000	0.982	0.017
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.982	0.017
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.982	0.017
C18.7 Sigmoid colon	0.017	0.983	0.000
D75.0 Familial erythrocytosis	0.000	0.983	0.016
D12.5 Sigmoid colon	0.016	0.984	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.016	0.984	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.985	0.015
D72.0 Genetic anomalies of leukocytes	0.000	0.985	0.015
D73.9 Disease of spleen, unspecified	0.000	0.985	0.015
D73.8 Other diseases of spleen	0.000	0.985	0.015
D73.4 Cyst of spleen	0.000	0.985	0.015
D73.3 Abscess of spleen	0.000	0.985	0.015
D73.2 Chronic congestive splenomegaly	0.000	0.985	0.015
D73.1 Hypersplenism	0.000	0.985	0.015
M20-M25 Other joint disorders	0.000	0.985	0.015
D12.7 Rectosigmoid junction	0.015	0.985	0.000
D12.4 Descending colon	0.015	0.985	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.014	0.985	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.014	0.986	0.000
S61.0 Open wound of finger(s) without damage to nail	0.014	0.986	0.000
S61.8 Open wound of other parts of wrist and hand	0.014	0.986	0.000
S60-S69 Injuries to the wrist and hand	0.014	0.986	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.014	0.986	0.000
M24 Other specific joint derangements	0.000	0.986	0.014
D76.3 Other histiocytosis syndromes	0.000	0.987	0.013
S64.1 Injury of median nerve at wrist and hand level	0.013	0.987	0.000
S61 Open wound of wrist and hand	0.013	0.987	0.000
D73.5 Infarction of spleen	0.000	0.987	0.013
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.987	0.013
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.987	0.013
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.987	0.013
S64.9 Injury of unspecified nerve at wrist and hand level	0.013	0.987	0.000
S64.8 Injury of other nerves at wrist and hand level	0.013	0.987	0.000
E66.8 Other obesity	0.000	0.987	0.013
M21 Other acquired deformities of limbs	0.000	0.987	0.013
E06.5 Other chronic thyroiditis	0.010	0.987	0.003
E06.4 Drug-induced thyroiditis	0.010	0.987	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.010	0.987	0.003
E06.1 Subacute thyroiditis	0.010	0.987	0.003
E06.0 Acute thyroiditis	0.010	0.987	0.003
D74.9 Methaemoglobinaemia, unspecified	0.000	0.987	0.013
D74.8 Other methaemoglobinaemias	0.000	0.987	0.013
D74.0 Congenital methaemoglobinaemia	0.000	0.987	0.013
J98.4 Other disorders of lung	0.013	0.987	0.000
M24.1 Other articular cartilage disorders	0.000	0.987	0.013
M24.0 Loose body in joint	0.000	0.987	0.013
D72.1 Eosinophilia	0.000	0.987	0.012
S60 Superficial injury of wrist and hand	0.012	0.987	0.000
M31 Other necrotising vasculopathies	0.000	0.987	0.012
S60.8 Other superficial injuries of wrist and hand	0.012	0.988	0.000
M32 Systemic lupus erythematosus	0.000	0.988	0.012
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.988	0.012
M24.02 Loose body in joint (Upper arm)	0.000	0.988	0.012
R94.3 Abnormal results of cardiovascular function studies	0.012	0.988	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.988	0.012
M34 Systemic sclerosis	0.000	0.988	0.011
M30 Polyarteritis nodosa and related conditions	0.000	0.989	0.011
M31.6 Other giant cell arteritis	0.000	0.989	0.011
M21.3 Wrist or foot drop (acquired)	0.000	0.989	0.011
M24.01 Loose body in joint (Shoulder region)	0.000	0.989	0.011
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.989	0.011
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.989	0.007
S60.9 Superficial injury of wrist and hand, unspecified	0.011	0.989	0.000
S68 Traumatic amputation of wrist and hand	0.011	0.989	0.000
D12.9 Anus and anal canal	0.011	0.989	0.000
D86 Sarcoidosis	0.000	0.989	0.011
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.989	0.010
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.989	0.010
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.990	0.010
E66 Obesity	0.000	0.990	0.010
M33 Dermatopolymyositis	0.000	0.990	0.010
S62 Fracture at wrist and hand level	0.010	0.990	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.990	0.010
D12.2 Ascending colon	0.010	0.990	0.000
I47.1 Supraventricular tachycardia	0.010	0.990	0.000
I47.2 Ventricular tachycardia	0.010	0.990	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.990	0.010
D86.9 Sarcoidosis, unspecified	0.000	0.990	0.010
I47 Paroxysmal tachycardia	0.010	0.990	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.990	0.010
M24.9 Joint derangement, unspecified	0.000	0.990	0.010
M21.4 Flat foot [pes planus] (acquired)	0.000	0.990	0.010
M24.2 Disorder of ligament	0.000	0.990	0.010
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.010	0.990	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.990	0.010
C71.9 Brain, unspecified	0.010	0.990	0.000
M24.6 Ankylosis of joint	0.000	0.990	0.010
E06.9 Thyroiditis, unspecified	0.006	0.990	0.004
E66.0 Obesity due to excess calories	0.000	0.990	0.010
S65 Injury of blood vessels at wrist and hand level	0.010	0.990	0.000
R47.0 Dysphasia and aphasia	0.000	0.990	0.010
E06.3 Autoimmune thyroiditis	0.007	0.990	0.003
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.990	0.010
M21.9 Acquired deformity of limb, unspecified	0.000	0.990	0.009
M21.8 Other specified acquired deformities of limbs	0.000	0.990	0.009
M21.7 Unequal limb length (acquired)	0.000	0.990	0.009
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.990	0.009
D86.8 Sarcoidosis of other and combined sites	0.000	0.990	0.010
S66 Injury of muscle and tendon at wrist and hand level	0.010	0.990	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.990	0.009
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.990	0.009
I47.9 Paroxysmal tachycardia, unspecified	0.009	0.991	0.000
M24.09 Loose body in joint (Site unspecified)	0.000	0.991	0.009
M24.08 Loose body in joint (Other)	0.000	0.991	0.009
M24.06 Loose body in joint-Lower leg	0.000	0.991	0.009
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.991	0.009
M24.04 Loose body in joint (Hand)	0.000	0.991	0.009
M24.03 Loose body in joint (Forearm)	0.000	0.991	0.009
M24.00 Loose body in joint (Multiple sites)	0.000	0.991	0.009
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.991	0.009
M24.18 Other articular cartilage disorders (Other)	0.000	0.991	0.009
M24.14 Other articular cartilage disorders (Hand)	0.000	0.991	0.009
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.991	0.009
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.991	0.009
D86.0 Sarcoidosis of lung	0.000	0.991	0.009
S68.0 Traumatic amputation of thumb (complete)(partial)	0.009	0.991	0.000
C18 Malignant neoplasm of colon	0.009	0.991	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.009	0.991	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.991	0.009
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.991	0.009
M31.2 Lethal midline granuloma	0.000	0.991	0.009
M31.1 Thrombotic microangiopathy	0.000	0.991	0.009
M31.0 Hypersensitivity angiitis	0.000	0.991	0.009
M34.9 Systemic sclerosis, unspecified	0.000	0.991	0.009
S60.7 Multiple superficial injuries of wrist and hand	0.009	0.991	0.000
S60.1 Contusion of finger(s) with damage to nail	0.009	0.991	0.000
C71.0 Cerebrum, except lobes and ventricles	0.009	0.991	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.991	0.009
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.991	0.009
D12.1 Appendix	0.009	0.991	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.991	0.009
M21.6 Other acquired deformities of ankle and foot	0.000	0.991	0.009
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.991	0.009
M32.8 Other forms of systemic lupus erythematosus	0.000	0.991	0.009
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.991	0.009
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.991	0.009
M31.3 Wegener's granulomatosis	0.000	0.991	0.009
C71 Malignant neoplasm of brain	0.009	0.991	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.991	0.009
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.991	0.009
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.991	0.009
S62.7 Multiple fractures of fingers	0.009	0.991	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.991	0.009
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.991	0.009
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.009	0.991	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.991	0.009
S67 Crushing injury of wrist and hand	0.009	0.991	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.991	0.009
M24.7 Protrusio acetabuli	0.000	0.991	0.008
D80-D89 Certain disorders involving the immune mechanism	0.000	0.991	0.009
S63.3 Traumatic rupture of ligament of wrist and carpus	0.009	0.991	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.991	0.008
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.991	0.008
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.991	0.008
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.991	0.008
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.991	0.008
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.991	0.008
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.991	0.008
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.991	0.008
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.009	0.991	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.991	0.008
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.991	0.008
M34.0 Progressive systemic sclerosis	0.000	0.991	0.008
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.991	0.008
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.991	0.008
M30.2 Juvenile polyarteritis	0.000	0.991	0.008
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.992	0.008
C77.2 Intra-abdominal lymph nodes	0.008	0.992	0.000
E04 Other non-toxic goitre	0.007	0.992	0.001
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.992	0.008
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.992	0.008
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.992	0.008
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.992	0.008
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.992	0.008
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.992	0.008
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.992	0.008
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.992	0.008
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.992	0.008
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.992	0.008
C18.1 Appendix	0.008	0.992	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.992	0.008
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.992	0.008
M36.3 Arthropathy in other blood disorders	0.000	0.992	0.008
M36.2 Haemophilic arthropathy	0.000	0.992	0.008
M36.1 Arthropathy in neoplastic disease	0.000	0.992	0.008
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.992	0.008
M31.9 Necrotising vasculopathy, unspecified	0.000	0.992	0.008
M24.23 Disorder of ligament (Forearm)	0.000	0.992	0.008
E05.8 Other thyrotoxicosis	0.003	0.992	0.005
E05.5 Thyroid crisis or storm	0.003	0.992	0.005
E05.4 Thyrotoxicosis factitia	0.003	0.992	0.005
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.992	0.005
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.992	0.005
C71.2 Temporal lobe	0.008	0.992	0.000
M31.7 Microscopic polyangiitis	0.000	0.992	0.008
M24.07 Loose body in joint (Ankle and foot)	0.000	0.992	0.008
D86.3 Sarcoidosis of skin	0.000	0.992	0.008
M24.5 Contracture of joint	0.000	0.992	0.008
S62.5 Fracture of thumb	0.008	0.992	0.000
M33.2 Polymyositis	0.000	0.992	0.008
M34.1 CR(E)ST syndrome	0.000	0.992	0.008
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.008	0.992	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.008	0.992	0.000
S68.4 Traumatic amputation of hand at wrist level	0.008	0.992	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.008	0.992	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.992	0.008
C18.6 Descending colon	0.008	0.992	0.000
I47.0 Reentry ventricular arrhythmia	0.008	0.992	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.992	0.008
D41.4 Bladder	0.008	0.992	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.992	0.005
E66.1 Drug-induced obesity	0.000	0.992	0.008
S66.8 Injury of other muscles and tendons at wrist and hand level	0.008	0.992	0.000
S62.70 Multiple fractures of fingers (closed)	0.008	0.992	0.000
C18.0 Caecum	0.008	0.992	0.000
M33.9 Dermatopolymyositis, unspecified	0.000	0.992	0.008
M33.0 Juvenile dermatomyositis	0.000	0.992	0.008
S62.4 Multiple fractures of metacarpal bones	0.008	0.992	0.000
M24.21 Disorder of ligament (Shoulder region)	0.000	0.992	0.008
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.992	0.008
S62.1 Fracture of other carpal bone(s)	0.008	0.992	0.000
S60.2 Contusion of other parts of wrist and hand	0.007	0.992	0.000
S64.3 Injury of digital nerve of thumb	0.007	0.992	0.000
S60.0 Contusion of finger(s) without damage to nail	0.007	0.992	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.992	0.007
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.992	0.007
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.992	0.007
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.992	0.007
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.992	0.007
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.008	0.992	0.000
M21.2 Flexion deformity	0.000	0.992	0.007
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.992	0.007
C18.2 Ascending colon	0.008	0.992	0.000
S65.1 Injury of radial artery at wrist and hand level	0.007	0.992	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.992	0.007
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.992	0.007
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.992	0.007
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.992	0.007
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.992	0.007
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.992	0.007
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.992	0.007
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.992	0.007
M30.0 Polyarteritis nodosa	0.000	0.992	0.007
M35 Other systemic involvement of connective tissue	0.000	0.992	0.008
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.992	0.007
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.007	0.993	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.993	0.007
M24.98 Joint derangement, unspecified (Other)	0.000	0.993	0.007
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.993	0.007
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.993	0.007
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
M24.94 Joint derangement, unspecified (Hand)	0.000	0.993	0.007
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.993	0.007
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.993	0.007
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.993	0.007
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.993	0.007
S63.5 Sprain and strain of wrist	0.007	0.993	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.007	0.993	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.993	0.007
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.007	0.993	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.993	0.007
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.993	0.007
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.993	0.007
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.993	0.007
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.993	0.007
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.993	0.007
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.993	0.007
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.993	0.007
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.993	0.007
S63.1 Dislocation finger	0.007	0.993	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.007	0.993	0.000
S63.2 Multiple dislocations of fingers	0.007	0.993	0.000
M24.29 Disorder of ligament (Site unspecified)	0.000	0.993	0.007
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.993	0.007
M24.22 Disorder of ligament (Upper arm)	0.000	0.993	0.007
M24.20 Disorder of ligament (Multiple sites)	0.000	0.993	0.007
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.993	0.007
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.007	0.993	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.993	0.007
M24.68 Ankylosis of joint (Other)	0.000	0.993	0.007
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.993	0.007
M24.64 Ankylosis of joint (Hand)	0.000	0.993	0.007
M24.63 Ankylosis of joint (Forearm)	0.000	0.993	0.007
M24.62 Ankylosis of joint (Upper arm)	0.000	0.993	0.007
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.993	0.007
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.993	0.007
S62.2 Fracture of first metacarpal bone	0.007	0.993	0.000
S62.3 Fracture of other metacarpal bone	0.007	0.993	0.000
S65.5 Injury of blood vessel(s) of other finger	0.007	0.993	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.007	0.993	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.007	0.993	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.007	0.993	0.000
S65.4 Injury of blood vessel(s) of thumb	0.007	0.993	0.000
S65.3 Injury of deep palmar arch	0.007	0.993	0.000
S65.2 Injury of superficial palmar arch	0.007	0.993	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations