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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2856718
log Bayes Factor = 145.895
Chromosome 6   position 32,670,255  (GRCh37) Explore rs2856718 on Ensembl!
Variant rs2856718 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
N48 Other disorders of penis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
N48.6 Balanitis xerotica obliterans
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.000 0.002 0.998
E10.2 With renal complications
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
N48.1 Balanoposthitis
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
N40-N51 Diseases of male genital organs
0.992 0.008 0.000
E10.5 With peripheral circulatory complications
0.000 0.008 0.992
N48.0 Leukoplakia of penis
0.979 0.021 0.000
M35.3 Polymyalgia rheumatica
0.000 0.034 0.966
M35.0 Sicca syndrome [Sjogren]
0.000 0.036 0.964
M35 Other systemic involvement of connective tissue
0.000 0.037 0.963
L90.0 Lichen sclerosus et atrophicus
0.953 0.047 0.000
L40 Psoriasis
0.945 0.055 0.000
E50-E64 Other nutritional deficiencies
0.000 0.056 0.944
D07.1 Vulva
0.925 0.075 0.000
E55 Vitamin D deficiency
0.000 0.078 0.922
N48.8 Other specified disorders of penis
0.913 0.087 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.093 0.907
D07 Carcinoma in situ of other and unspecified genital organs
0.906 0.094 0.000
L40.0 Psoriasis vulgaris
0.897 0.103 0.000
N48.2 Other inflammatory disorders of penis
0.894 0.106 0.000
D00-D09 In situ neoplasms
0.889 0.111 0.000
E10.0 With coma
0.000 0.116 0.884
L90 Atrophic disorders of skin
0.883 0.117 0.000
E06 Thyroiditis
0.000 0.122 0.878
D06 Carcinoma in situ of cervix uteri
0.870 0.130 0.000
L90.5 Scar conditions and fibrosis of skin
0.868 0.132 0.000
N48.5 Ulcer of penis
0.859 0.141 0.000
N44 Torsion of testis
0.847 0.153 0.000
D06.9 Cervix, unspecified
0.847 0.153 0.000
C21.1 Anal canal
0.839 0.161 0.000
C21 Malignant neoplasm of anus and anal canal
0.832 0.168 0.000
C21.0 Anus, unspecified
0.832 0.168 0.000
D07.4 Penis
0.829 0.171 0.000
N48.9 Disorder of penis, unspecified
0.828 0.172 0.000
E40-E46 Malnutrition
0.000 0.177 0.823
N45 Orchitis and epididymitis
0.813 0.187 0.000
E03 Other hypothyroidism
0.651 0.190 0.159
E14.6 With other specified complications
0.000 0.195 0.805
E10.8 With unspecified complications
0.000 0.199 0.801
D04 Carcinoma in situ of skin
0.797 0.203 0.000
N42 Other disorders of prostate
0.793 0.207 0.000
M35.1 Other overlap syndromes
0.000 0.213 0.787
E14.8 With unspecified complications
0.000 0.216 0.784
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.223 0.777
E07 Other disorders of thyroid
0.000 0.229 0.771
E14.5 With peripheral circulatory complications
0.000 0.234 0.766
L40.4 Guttate psoriasis
0.760 0.240 0.000
D09 Carcinoma in situ of other and unspecified sites
0.759 0.241 0.000
L40.8 Other psoriasis
0.753 0.247 0.000
N48.4 Impotence of organic origin
0.753 0.247 0.000
M35.2 Behcet's disease
0.000 0.247 0.753
E10.6 With other specified complications
0.000 0.247 0.752
D04.7 Skin of lower limb, including hip
0.749 0.251 0.000
E51 Thiamine deficiency
0.000 0.254 0.746
D01 Carcinoma in situ of other and unspecified digestive organs
0.742 0.258 0.000
E06.9 Thyroiditis, unspecified
0.000 0.263 0.737
N48.3 Priapism
0.734 0.266 0.000
E14.9 Without complications
0.000 0.267 0.733
E06.3 Autoimmune thyroiditis
0.000 0.269 0.731
D03 Melanoma in situ
0.728 0.272 0.000
L40.1 Generalised pustular psoriasis
0.727 0.273 0.000
E14.2 Withrenal complications
0.000 0.273 0.726
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.284 0.715
E14.0 With coma
0.000 0.284 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.289 0.711
D04.9 Skin, unspecified
0.709 0.291 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.701 0.299 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.700 0.300 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.305 0.695
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.310 0.690
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.310 0.690
M35.5 Multifocal fibrosclerosis
0.000 0.310 0.690
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.310 0.690
D06.1 Exocervix
0.687 0.313 0.000
L40.5 Arthropathic psoriasis
0.681 0.319 0.000
E14.1 With ketoacidosis
0.000 0.322 0.678
L40.2 Acrodermatitis continua
0.678 0.322 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.323 0.677
E63 Other nutritional deficiencies
0.000 0.323 0.677
E50 Vitamin A deficiency
0.000 0.323 0.677
E60 Dietary zinc deficiency
0.000 0.323 0.677
E59 Dietary selenium deficiency
0.000 0.323 0.677
E54 Ascorbic acid deficiency
0.000 0.323 0.677
E52 Niacin deficiency [pellagra]
0.000 0.323 0.677
D09.1 Other and unspecified urinary organs
0.670 0.330 0.000
D06.0 Endocervix
0.670 0.330 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.662 0.338 0.000
E55.0 Rickets, active
0.000 0.339 0.661
E05.8 Other thyrotoxicosis
0.000 0.341 0.659
D02 Carcinoma in situ of middle ear and respiratory system
0.658 0.342 0.000
E07.8 Other specified disorders of thyroid
0.000 0.342 0.658
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.655 0.345 0.000
D04.3 Skin of other and unspecified parts of face
0.654 0.346 0.000
D07.6 Other and unspecified male genital organs
0.650 0.350 0.000
D07.3 Other and unspecified female genital organs
0.650 0.350 0.000
D07.0 Endometrium
0.650 0.350 0.000
D01.3 Anus and anal canal
0.650 0.350 0.000
L40.3 Pustulosis palmaris et plantaris
0.644 0.356 0.000
M35.7 Hypermobility syndrome
0.000 0.360 0.640
N42.8 Other specified disorders of prostate
0.639 0.361 0.000
L90.8 Other atrophic disorders of skin
0.639 0.361 0.000
L90.9 Atrophic disorder of skin, unspecified
0.633 0.367 0.000
L90.6 Striae atrophicae
0.633 0.367 0.000
L90.4 Acrodermatitis chronica atrophicans
0.633 0.367 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.633 0.367 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.633 0.367 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.633 0.367 0.000
D07.2 Vagina
0.632 0.368 0.000
E06.4 Drug-induced thyroiditis
0.000 0.371 0.629
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.371 0.629
E06.1 Subacute thyroiditis
0.000 0.371 0.629
E06.0 Acute thyroiditis
0.000 0.371 0.629
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.627 0.373 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.626 0.374 0.000
D06.7 Other parts of cervix
0.623 0.376 0.000
D09.7 Carcinoma in situ of other specified sites
0.623 0.376 0.000
D04.4 Skin of scalp and neck
0.622 0.378 0.000
N42.3 Dysplasia of prostate
0.621 0.379 0.000
N42.9 Disorder of prostate, unspecified
0.621 0.379 0.000
N42.1 Congestion and haemorrhage of prostate
0.621 0.379 0.000
E53 Deficiency of other B group vitamins
0.000 0.381 0.619
E58 Dietary calcium deficiency
0.000 0.382 0.617
E06.5 Other chronic thyroiditis
0.000 0.384 0.615
E14.4 With neurological complications
0.000 0.385 0.614
M35.8 Other specified systemic involvement of connective tissue
0.000 0.391 0.609
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.394 0.606
E61 Deficiency of other nutrient elements
0.000 0.396 0.604
E51.2 Wernicke's encephalopathy
0.000 0.396 0.604
E03.0 Congenital hypothyroidism with diffuse goitre
0.501 0.398 0.101
D03.6 Melanoma in situ of upper limb, including shoulder
0.600 0.400 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.511 0.401 0.088
C21.2 Cloacogenic zone
0.596 0.404 0.000
E56 Other vitamin deficiencies
0.000 0.404 0.596
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.410 0.590
E45 Retarded development following protein-energy malnutrition
0.000 0.410 0.590
E43 Unspecified severe protein-energy malnutrition
0.000 0.410 0.590
E42 Marasmic kwashiorkor
0.000 0.410 0.590
E41 Nutritional marasmus
0.000 0.410 0.590
E40 Kwashiorkor
0.000 0.410 0.590
D03.5 Melanoma in situ of trunk
0.581 0.419 0.000
E03.5 Myxoedema coma
0.466 0.419 0.114
E03.4 Atrophy of thyroid (acquired)
0.466 0.419 0.114
E03.3 Postinfectious hypothyroidism
0.466 0.419 0.114
D03.8 Melanoma in situ of other sites
0.577 0.423 0.000
D04.8 Skin of other sites
0.572 0.428 0.000
D04.0 Skin of lip
0.572 0.428 0.000
E03.1 Congenital hypothyroidism without goitre
0.457 0.431 0.112
N42.2 Atrophy of prostate
0.564 0.436 0.000
E07.1 Dyshormogenetic goitre
0.000 0.447 0.553
E07.0 Hypersecretion of calcitonin
0.000 0.447 0.553
D09.9 Carcinoma in situ, unspecified
0.544 0.456 0.000
D09.3 Thyroid and other endocrine glands
0.544 0.456 0.000
D09.2 Eye
0.544 0.456 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.544 0.456 0.000
E04 Other non-toxic goitre
0.000 0.463 0.537
N41 Inflammatory diseases of prostate
0.536 0.464 0.000
E03.8 Other specified hypothyroidism
0.440 0.464 0.095
E51.9 Thiamine deficiency, unspecified
0.000 0.465 0.535
E51.8 Other manifestations of thiamine deficiency
0.000 0.465 0.535
E51.1 Beriberi
0.000 0.465 0.535
D01.9 Digestive organ, unspecified
0.532 0.468 0.000
D01.7 Other specified digestive organs
0.532 0.468 0.000
D01.5 Liver, gallbladder and bile ducts
0.532 0.468 0.000
D01.4 Other and unspecified parts of intestine
0.532 0.468 0.000
D01.2 Rectum
0.532 0.468 0.000
D01.1 Rectosigmoid junction
0.532 0.468 0.000
D04.1 Skin of eyelid, including canthus
0.531 0.468 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.474 0.526
E20-E35 Disorders of other endocrine glands
0.000 0.474 0.526
D03.9 Melanoma in situ, unspecified
0.522 0.478 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.522 0.478 0.000
D03.0 Melanoma in situ of lip
0.522 0.478 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.479 0.520
E16.1 Other hypoglycaemia
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.503 0.497 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.503 0.497 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.503 0.497 0.000
D01.0 Colon
0.501 0.499 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.502 0.498
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.505 0.495
N51.2 Balanitis in diseases classified elsewhere
0.492 0.508 0.000
E27 Other disorders of adrenal gland
0.000 0.512 0.488
E50.9 Vitamin A deficiency, unspecified
0.000 0.515 0.485
E50.8 Other manifestations of vitamin A deficiency
0.000 0.515 0.485
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.515 0.485
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.515 0.485
E50.5 Vitamin A deficiency with night blindness
0.000 0.515 0.485
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.515 0.485
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.515 0.485
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.515 0.485
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.515 0.485
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.515 0.485
E63.9 Nutritional deficiency, unspecified
0.000 0.515 0.485
E63.8 Other specified nutritional deficiencies
0.000 0.515 0.485
E63.1 Imbalance of constituents of food intake
0.000 0.515 0.485
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.515 0.485
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.515 0.485
E64.8 Sequelae of other nutritional deficiencies
0.000 0.515 0.485
E64.3 Sequelae of rickets
0.000 0.515 0.485
E64.2 Sequelae of vitamin C deficiency
0.000 0.515 0.485
E64.1 Sequelae of vitamin A deficiency
0.000 0.515 0.485
E64.0 Sequelae of protein-energy malnutrition
0.000 0.515 0.485
D02.0 Larynx
0.484 0.516 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.518 0.482
D02.2 Bronchus and lung
0.480 0.520 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.521 0.479
D02.4 Respiratory system, unspecified
0.472 0.528 0.000
D02.3 Other parts of respiratory system
0.472 0.528 0.000
D02.1 Trachea
0.472 0.528 0.000
K90 Intestinal malabsorption
0.000 0.533 0.467
N46 Male infertility
0.466 0.534 0.001
N30.2 Other chronic cystitis
0.465 0.535 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.465 0.535 0.000
L40-L45 Papulosquamous disorders
0.465 0.535 0.000
E34 Other endocrine disorders
0.000 0.538 0.462
E61.2 Magnesium deficiency
0.000 0.538 0.461
E13 Other specified diabetes mellitus
0.001 0.540 0.459
D00.0 Lip, oral cavity and pharynx
0.458 0.542 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.543 0.457
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.550 0.450
D00.2 Stomach
0.449 0.551 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.445 0.555 0.000
E53.1 Pyridoxine deficiency
0.000 0.556 0.444
E53.0 Riboflavin deficiency
0.000 0.556 0.444
H36 Retinal disorders in diseases classified elsewhere
0.000 0.556 0.444
N90.7 Vulvar cyst
0.441 0.559 0.000
N30 Cystitis
0.438 0.562 0.000
N90.4 Leukoplakia of vulva
0.437 0.563 0.000
D04.5 Skin of trunk
0.436 0.564 0.000
G36 Other acute disseminated demyelination
0.000 0.565 0.435
E61.9 Deficiency of nutrient element, unspecified
0.000 0.567 0.433
E61.8 Deficiency of other specified nutrient elements
0.000 0.567 0.433
E61.7 Deficiency of multiple nutrient elements
0.000 0.567 0.433
E61.6 Vanadium deficiency
0.000 0.567 0.433
E61.5 Molybdenum deficiency
0.000 0.567 0.433
E61.4 Chromium deficiency
0.000 0.567 0.433
E61.3 Manganese deficiency
0.000 0.567 0.433
E61.0 Copper deficiency
0.000 0.567 0.433
E56.9 Vitamin deficiency, unspecified
0.000 0.572 0.427
E56.8 Deficiency of other vitamins
0.000 0.572 0.427
E56.0 Deficiency of vitamin E
0.000 0.572 0.427
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.573 0.427
D00.1 Oesophagus
0.426 0.574 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.577 0.423
E44.0 Moderate protein-energy malnutrition
0.000 0.577 0.423
N41.0 Acute prostatitis
0.420 0.580 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.581 0.419
N30.0 Acute cystitis
0.414 0.586 0.000
N90.3 Dysplasia of vulva, unspecified
0.413 0.587 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.409 0.591 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.594 0.406
D09.0 Bladder
0.404 0.596 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.402 0.598 0.000
N30.1 Interstitial cystitis (chronic)
0.402 0.598 0.000
E28 Ovarian dysfunction
0.000 0.601 0.399
N90.1 Moderate vulvar dysplasia
0.394 0.605 0.000
E34.0 Carcinoid syndrome
0.000 0.606 0.394
N43 Hydrocele and spermatocele
0.392 0.608 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.390 0.610 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.390 0.610 0.000
D04.2 Skin of ear and external auricular canal
0.389 0.610 0.000
L42 Pityriasis rosea
0.388 0.612 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.614 0.386
E04.8 Other specified non-toxic goitre
0.000 0.614 0.385
N41.3 Prostatocystitis
0.385 0.615 0.000
N41.2 Abscess of prostate
0.385 0.615 0.000
D03.4 Melanoma in situ of scalp and neck
0.378 0.622 0.000
N41.1 Chronic prostatitis
0.378 0.622 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.623 0.377
G37.4 Subacute necrotising myelitis
0.000 0.623 0.377
G37.2 Central pontine myelinolysis
0.000 0.623 0.377
G37.1 Central demyelination of corpus callosum
0.000 0.623 0.377
G37.0 Diffuse sclerosis
0.000 0.623 0.377
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.623 0.377
E32 Diseases of thymus
0.000 0.623 0.377
E31 Polyglandular dysfunction
0.000 0.623 0.377
E30 Disorders of puberty, not elsewhere classified
0.000 0.623 0.377
N30.3 Trigonitis
0.375 0.625 0.000
L44 Other papulosquamous disorders
0.374 0.626 0.000
N90.0 Mild vulvar dysplasia
0.372 0.628 0.000
E26 Hyperaldosteronism
0.000 0.628 0.372
E29 Testicular dysfunction
0.000 0.634 0.366
E34.9 Endocrine disorder, unspecified
0.000 0.639 0.361
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.641 0.359
N30.4 Irradiation cystitis
0.358 0.642 0.000
N41.8 Other inflammatory diseases of prostate
0.353 0.647 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.649 0.351
E27.5 Adrenomedullary hyperfunction
0.000 0.650 0.350
E27.0 Other adrenocortical overactivity
0.000 0.650 0.350
E22 Hyperfunction of pituitary gland
0.000 0.651 0.349
E34.8 Other specified endocrine disorders
0.000 0.651 0.349
E56.1 Deficiency of vitamin K
0.001 0.653 0.346
E20 Hypoparathyroidism
0.000 0.660 0.340
J45 Asthma
0.338 0.662 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.336 0.663 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.665 0.335
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.665 0.335
K90.1 Tropical sprue
0.000 0.665 0.335
D04.6 Skin of upper limb, including shoulder
0.334 0.666 0.000
L41 Parapsoriasis
0.333 0.667 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.333 0.667 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.668 0.332
E34.5 Androgen resistance syndrome
0.000 0.669 0.331
E34.4 Constitutional tall stature
0.000 0.669 0.331
E34.3 Short stature, not elsewhere classified
0.000 0.669 0.331
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.669 0.331
E34.1 Other hypersecretion of intestinal hormones
0.000 0.669 0.331
N42.0 Calculus of prostate
0.331 0.669 0.000
K90.8 Other intestinal malabsorption
0.000 0.669 0.331
E13.8 With unspecified complications
0.001 0.670 0.329
E13.7 With multiple complications
0.001 0.670 0.329
E13.6 With other specified complications
0.001 0.670 0.329
E13.5 With peripheral circulatory complications
0.001 0.670 0.329
E13.4 With neurological complications
0.001 0.670 0.329
E13.2 With renal complications
0.001 0.670 0.329
E13.1 With ketoacidosis
0.001 0.670 0.329
E13.0 With coma
0.001 0.670 0.329
N30.8 Other cystitis
0.323 0.677 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.323 0.677 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.679 0.321
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.319 0.680 0.000
E25 Adrenogenital disorders
0.000 0.681 0.318
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.682 0.318
E13.3 With ophthalmic complications
0.001 0.686 0.313
E61.1 Iron deficiency
0.000 0.687 0.313
D07.5 Prostate
0.312 0.688 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.688 0.312
G36.8 Other specified acute disseminated demyelination
0.000 0.688 0.312
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.688 0.312
G36.0 Neuromyelitis optica [Devic]
0.000 0.688 0.312
E28.2 Polycystic ovarian syndrome
0.000 0.689 0.311
L44.0 Pityriasis rubra pilaris
0.309 0.691 0.000
N43.2 Other hydrocele
0.303 0.697 0.000
E67 Other hyperalimentation
0.000 0.699 0.300
E68 Sequelae of hyperalimentation
0.000 0.699 0.300
N43.1 Infected hydrocele
0.294 0.706 0.000
E22.1 Hyperprolactinaemia
0.000 0.711 0.289
N49.2 Inflammatory disorders of scrotum
0.286 0.713 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.714 0.286
E28.8 Other ovarian dysfunction
0.000 0.714 0.286
E28.1 Androgen excess
0.000 0.714 0.286
E28.0 Oestrogen excess
0.000 0.714 0.286
E27.9 Disorder of adrenal gland, unspecified
0.000 0.717 0.283
E53.8 Deficiency of other specified B group vitamins
0.000 0.718 0.282
E28.3 Primary ovarian failure
0.000 0.718 0.281
N43.0 Encysted hydrocele
0.281 0.719 0.000
E65 Localised adiposity
0.000 0.724 0.275
N90.6 Hypertrophy of vulva
0.272 0.727 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.729 0.270
E30.8 Other disorders of puberty
0.000 0.729 0.270
E30.1 Precocious puberty
0.000 0.729 0.270
E30.0 Delayed puberty
0.000 0.729 0.270
E31.9 Polyglandular dysfunction, unspecified
0.000 0.729 0.270
E31.8 Other polyglandular dysfunction
0.000 0.729 0.270
E31.1 Polyglandular hyperfunction
0.000 0.729 0.270
E31.0 Autoimmune polyglandular failure
0.000 0.729 0.270
E32.9 Disease of thymus, unspecified
0.000 0.729 0.270
E32.8 Other diseases of thymus
0.000 0.729 0.270
E32.1 Abscess of thymus
0.000 0.729 0.270
E32.0 Persistent hyperplasia of thymus
0.000 0.729 0.270
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.729 0.270
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.729 0.270
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.729 0.270
E29.1 Testicular hypofunction
0.000 0.731 0.269
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.731 0.268
L44.9 Papulosquamous disorder, unspecified
0.268 0.732 0.000
L44.8 Other specified papulosquamous disorders
0.268 0.732 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.268 0.732 0.000
L44.3 Lichen ruber moniliformis
0.268 0.732 0.000
L44.2 Lichen striatus
0.268 0.732 0.000
L44.1 Lichen nitidus
0.268 0.732 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.733 0.267
E26.8 Other hyperaldosteronism
0.000 0.733 0.267
E26.1 Secondary hyperaldosteronism
0.000 0.733 0.267
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.734 0.266
E29.8 Other testicular dysfunction
0.000 0.737 0.263
E29.0 Testicular hyperfunction
0.000 0.737 0.263
E26.0 Primary hyperaldosteronism
0.000 0.739 0.261
E11 Non-insulin-dependent diabetes mellitus
0.000 0.744 0.256
E04.9 Non-toxic goitre, unspecified
0.000 0.746 0.254
E23.7 Disorder of pituitary gland, unspecified
0.000 0.748 0.252
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.749 0.251
E22.8 Other hyperfunction of pituitary gland
0.000 0.749 0.251
E27.2 Addisonian crisis
0.000 0.751 0.249
J45.8 Mixed asthma
0.246 0.754 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.756 0.244
E20.8 Other hypoparathyroidism
0.000 0.756 0.244
E20.1 Pseudohypoparathyroidism
0.000 0.756 0.244
E20.0 Idiopathic hypoparathyroidism
0.000 0.756 0.244
J45.1 Nonallergic asthma
0.242 0.757 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.760 0.239
L41.9 Parapsoriasis, unspecified
0.239 0.761 0.000
L41.8 Other parapsoriasis
0.239 0.761 0.000
L41.5 Retiform parapsoriasis
0.239 0.761 0.000
L41.4 Large plaque parapsoriasis
0.239 0.761 0.000
L41.3 Small plaque parapsoriasis
0.239 0.761 0.000
L41.2 Lymphomatoid papulosis
0.239 0.761 0.000
L41.1 Pityriasis lichenoides chronica
0.239 0.761 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.239 0.761 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.770 0.230
E23.1 Drug-induced hypopituitarism
0.000 0.770 0.230
E25.9 Adrenogenital disorder, unspecified
0.000 0.771 0.228
E25.8 Other adrenogenital disorders
0.000 0.771 0.228
E23.6 Other disorders of pituitary gland
0.000 0.777 0.223
L43 Lichen planus
0.222 0.778 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.220 0.780 0.000
N90.5 Atrophy of vulva
0.219 0.781 0.000
E11.3 With ophthalmic complications
0.000 0.782 0.218
E67.8 Other specified hyperalimentation
0.000 0.784 0.215
E67.3 Hypervitaminosis D
0.000 0.784 0.215
E67.2 Megavitamin-B6 syndrome
0.000 0.784 0.215
E67.1 Hypercarotenaemia
0.000 0.784 0.215
E67.0 Hypervitaminosis A
0.000 0.784 0.215
E20.9 Hypoparathyroidism, unspecified
0.000 0.793 0.207
E23.0 Hypopituitarism
0.000 0.794 0.206
N41.9 Inflammatory disease of prostate, unspecified
0.199 0.801 0.000
J45.0 Predominantly allergic asthma
0.198 0.802 0.000
D05 Carcinoma in situ of breast
0.196 0.804 0.000
N43.4 Spermatocele
0.190 0.809 0.001
E11.5 With peripheral circulatory complications
0.000 0.809 0.191
E11.8 With unspecified complications
0.000 0.810 0.190
E11.0 With coma
0.000 0.812 0.188
E11.7 With multiple complications
0.000 0.816 0.184
E23.2 Diabetes insipidus
0.000 0.821 0.178
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.830 0.169
L43.8 Other lichen planus
0.164 0.836 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.837 0.163
L43.3 Subacute (active) lichen planus
0.159 0.841 0.000
L43.2 Lichenoid drug reaction
0.159 0.841 0.000
L43.1 Bullous lichen planus
0.159 0.841 0.000
L43.0 Hypertrophic lichen planus
0.159 0.841 0.000
E11.1 With ketoacidosis
0.000 0.844 0.156
D05.7 Other carcinoma in situ of breast
0.154 0.845 0.000
E11.6 With other specified complications
0.000 0.850 0.150
E11.4 With neurological complications
0.000 0.858 0.142
E11.2 With renal complications
0.000 0.859 0.141
N50 Other disorders of male genital organs
0.136 0.864 0.000
E70-E90 Metabolic disorders
0.000 0.864 0.136
E24 Cushing's syndrome
0.004 0.865 0.131
E83.1 Disorders of iron metabolism
0.000 0.868 0.132
E83 Disorders of mineral metabolism
0.000 0.871 0.129
D05.0 Lobular carcinoma in situ
0.120 0.880 0.000
N30.9 Cystitis, unspecified
0.117 0.883 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.884 0.116
E87.7 Fluid overload
0.000 0.884 0.116
E13.9 Without complications
0.001 0.886 0.113

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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