TreeWAS – Variant ID: rs2943652

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	0.998	0.002	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.997	0.003	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.992	0.008	0.000
I25.1 Atherosclerotic heart disease	0.977	0.023	0.000
I25.5 Ischaemic cardiomyopathy	0.953	0.047	0.000
E11 Non-insulin-dependent diabetes mellitus	0.885	0.115	0.000
E11.3 With ophthalmic complications	0.850	0.150	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.831	0.169	0.000
E10-E14 Diabetes mellitus	0.817	0.183	0.000
E10 Insulin-dependent diabetes mellitus	0.792	0.208	0.000
E10.1 With ketoacidosis	0.769	0.231	0.000
E78.0 Pure hypercholesterolaemia	0.750	0.250	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.745	0.255	0.000
I25.2 Old myocardial infarction	0.732	0.268	0.000
I25.3 Aneurysm of heart	0.731	0.269	0.000
E78.5 Hyperlipidaemia, unspecified	0.707	0.293	0.000
I25.6 Silent myocardial ischaemia	0.706	0.294	0.000
E11.7 With multiple complications	0.700	0.300	0.000
E10.5 With peripheral circulatory complications	0.693	0.307	0.000
E13 Other specified diabetes mellitus	0.690	0.310	0.000
E11.8 With unspecified complications	0.672	0.328	0.000
E78.2 Mixed hyperlipidaemia	0.667	0.333	0.000
E78.4 Other hyperlipidaemia	0.645	0.355	0.000
E10.8 With unspecified complications	0.645	0.355	0.000
E78.1 Pure hyperglyceridaemia	0.644	0.356	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.634	0.366	0.000
I20-I25 Ischaemic heart diseases	0.630	0.370	0.000
E78.8 Other disorders of lipoprotein metabolism	0.628	0.372	0.000
E10.0 With coma	0.626	0.374	0.000
I20.9 Angina pectoris, unspecified	0.623	0.377	0.000
E13.9 Without complications	0.621	0.379	0.000
I20 Angina pectoris	0.620	0.380	0.000
E10.7 With multiple complications	0.618	0.382	0.000
E11.4 With neurological complications	0.596	0.403	0.000
E12 Malnutrition-related diabetes mellitus	0.586	0.414	0.000
E11.6 With other specified complications	0.548	0.451	0.000
E11.0 With coma	0.545	0.455	0.000
E10.3 With ophthalmic complications	0.518	0.482	0.000
E10.6 With other specified complications	0.516	0.484	0.000
E11.1 With ketoacidosis	0.501	0.499	0.000
E10.9 Without complications	0.497	0.503	0.000
E13.8 With unspecified complications	0.495	0.505	0.000
E13.7 With multiple complications	0.495	0.505	0.000
E13.6 With other specified complications	0.495	0.505	0.000
E13.5 With peripheral circulatory complications	0.495	0.505	0.000
E13.4 With neurological complications	0.495	0.505	0.000
E13.2 With renal complications	0.495	0.505	0.000
E13.1 With ketoacidosis	0.495	0.505	0.000
E13.0 With coma	0.495	0.505	0.000
E78.3 Hyperchylomicronaemia	0.492	0.508	0.000
E14 Unspecified diabetes mellitus	0.486	0.514	0.000
I20.0 Unstable angina	0.485	0.515	0.000
E10.2 With renal complications	0.474	0.526	0.000
I22 Subsequent myocardial infarction	0.472	0.528	0.000
E10.4 With neurological complications	0.439	0.561	0.000
E13.3 With ophthalmic complications	0.434	0.566	0.000
E78.6 Lipoprotein deficiency	0.431	0.568	0.000
E14.5 With peripheral circulatory complications	0.429	0.571	0.000
E12.9 Without complications	0.420	0.580	0.000
E12.8 With unspecified complications	0.420	0.580	0.000
E12.7 With multiple complications	0.420	0.580	0.000
E12.6 With other specified complications	0.420	0.580	0.000
E12.5 With peripheral circulatory complications	0.420	0.580	0.000
E12.4 With neurological complications	0.420	0.580	0.000
E12.3 With ophthalmic complications	0.420	0.580	0.000
E12.2 With renal complications	0.420	0.580	0.000
E12.1 With ketoacidosis	0.420	0.580	0.000
E12.0 With coma	0.420	0.580	0.000
E11.2 With renal complications	0.396	0.604	0.000
I23 Certain current complications following acute myocardial infarction	0.381	0.619	0.000
I25.4 Coronary artery aneurysm	0.379	0.620	0.001
E14.4 With neurological complications	0.367	0.633	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.350	0.650	0.000
E14.7 With multiple complications	0.348	0.652	0.000
E14.2 Withrenal complications	0.345	0.655	0.000
E14.8 With unspecified complications	0.344	0.655	0.000
E11.5 With peripheral circulatory complications	0.344	0.655	0.000
I22.8 Subsequent myocardial infarction of other sites	0.344	0.656	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.340	0.660	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.340	0.660	0.000
E14.0 With coma	0.329	0.670	0.000
E14.3 With ophthalmic complications	0.318	0.682	0.000
E14.9 Without complications	0.305	0.695	0.000
E14.6 With other specified complications	0.285	0.714	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.273	0.727	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.273	0.727	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.273	0.727	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.273	0.727	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.273	0.727	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.273	0.727	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.273	0.727	0.000
E14.1 With ketoacidosis	0.247	0.752	0.000
I20.1 Angina pectoris with documented spasm	0.247	0.752	0.000
E70-E90 Metabolic disorders	0.240	0.760	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.239	0.761	0.000
I24 Other acute ischaemic heart diseases	0.237	0.763	0.000
I20.8 Other forms of angina pectoris	0.233	0.767	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.207	0.793	0.000
I23.8 Other current complications following acute myocardial infarction	0.202	0.798	0.001
E73 Lactose intolerance	0.196	0.804	0.000
E85 Amyloidosis	0.191	0.809	0.000
I24.1 Dressler's syndrome	0.188	0.812	0.000
E16 Other disorders of pancreatic internal secretion	0.184	0.816	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.172	0.827	0.000
E77 Disorders of glycoprotein metabolism	0.172	0.827	0.000
E76 Disorders of glycosaminoglycan metabolism	0.172	0.827	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.172	0.827	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.172	0.827	0.000
E72 Other disorders of amino-acid metabolism	0.171	0.829	0.000
E79 Disorders of purine and pyrimidine metabolism	0.171	0.829	0.000
E16.2 Hypoglycaemia, unspecified	0.170	0.830	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.166	0.834	0.000
E73.9 Lactose intolerance, unspecified	0.163	0.836	0.000
E74 Other disorders of carbohydrate metabolism	0.161	0.838	0.000
E85.4 Organ-limited amyloidosis	0.161	0.839	0.000
E70 Disorders of aromatic amino-acid metabolism	0.160	0.840	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.157	0.843	0.000
I60 Subarachnoid haemorrhage	0.151	0.849	0.000
E15 Nondiabetic hypoglycaemic coma	0.148	0.851	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.148	0.852	0.000
E88 Other metabolic disorders	0.143	0.857	0.000
E85.9 Amyloidosis, unspecified	0.142	0.857	0.000
E84 Cystic fibrosis	0.141	0.859	0.000
E73.8 Other lactose intolerance	0.140	0.860	0.000
E73.1 Secondary lactase deficiency	0.140	0.860	0.000
E73.0 Congenital lactase deficiency	0.140	0.860	0.000
I24.8 Other forms of acute ischaemic heart disease	0.140	0.860	0.000
E80.2 Other porphyria	0.137	0.863	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.137	0.863	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.137	0.863	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.137	0.863	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.136	0.864	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.136	0.864	0.000
E85.3 Secondary systemic amyloidosis	0.133	0.866	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.133	0.867	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.132	0.868	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.132	0.868	0.000
E16.4 Abnormal secretion of gastrin	0.132	0.868	0.000
E16.3 Increased secretion of glucagon	0.132	0.868	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.132	0.868	0.000
I60-I69 Cerebrovascular diseases	0.131	0.869	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.130	0.870	0.000
E74.0 Glycogen storage disease	0.129	0.871	0.000
E80.6 Other disorders of bilirubin metabolism	0.127	0.872	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.127	0.873	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.126	0.874	0.000
Chapter IX Diseases of the circulatory system	0.126	0.874	0.000
E75.5 Other lipid storage disorders	0.124	0.876	0.000
E75.6 Lipid storage disorder, unspecified	0.124	0.876	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.124	0.876	0.000
E75.3 Sphingolipidosis, unspecified	0.124	0.876	0.000
E75.2 Other sphingolipidosis	0.124	0.876	0.000
E75.1 Other gangliosidosis	0.124	0.876	0.000
E75.0 GM2 gangliosidosis	0.124	0.876	0.000
E71.3 Disorders of fatty-acid metabolism	0.124	0.876	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.124	0.876	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.124	0.876	0.000
E71.0 Maple-syrup-urine disease	0.124	0.876	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.124	0.876	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.124	0.876	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.124	0.876	0.000
E76.2 Other mucopolysaccharidoses	0.124	0.876	0.000
E76.1 Mucopolysaccharidosis, type II	0.124	0.876	0.000
E76.0 Mucopolysaccharidosis, type I	0.124	0.876	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.124	0.876	0.000
E77.8 Other disorders of glycoprotein metabolism	0.124	0.876	0.000
E77.1 Defects in glycoprotein degradation	0.124	0.876	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.124	0.876	0.000
E85.8 Other amyloidosis	0.124	0.876	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.123	0.877	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.123	0.877	0.000
E72.5 Disorders of glycine metabolism	0.123	0.877	0.000
E72.4 Disorders of ornithine metabolism	0.123	0.877	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.123	0.877	0.000
E72.2 Disorders of urea cycle metabolism	0.123	0.877	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.123	0.877	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.123	0.877	0.000
E79.1 Lesch-Nyhan syndrome	0.123	0.877	0.000
I67.1 Cerebral aneurysm, nonruptured	0.122	0.878	0.000
I67 Other cerebrovascular diseases	0.122	0.878	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.121	0.878	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.120	0.880	0.000
E16.1 Other hypoglycaemia	0.120	0.880	0.000
E80.5 Crigler-Najjar syndrome	0.119	0.880	0.000
E80.3 Defects of catalase and peroxydase	0.119	0.880	0.000
E80.0 Hereditary erythropoietic porphyria	0.119	0.880	0.000
E72.0 Disorders of amino-acid transport	0.118	0.882	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.117	0.883	0.000
E40-E46 Malnutrition	0.116	0.883	0.000
E80.1 Porphyria cutanea tarda	0.116	0.884	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.116	0.884	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.116	0.884	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.116	0.884	0.000
E74.2 Disorders of galactose metabolism	0.116	0.884	0.000
E74.1 Disorders of fructose metabolism	0.116	0.884	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.115	0.885	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.115	0.885	0.000
E70.2 Disorders of tyrosine metabolism	0.115	0.885	0.000
E70.1 Other hyperphenylalaninaemias	0.115	0.885	0.000
E70.0 Classical phenylketonuria	0.115	0.885	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.114	0.886	0.000
I62 Other nontraumatic intracranial haemorrhage	0.113	0.887	0.000
I60.8 Other subarachnoid haemorrhage	0.112	0.888	0.000
E88.9 Metabolic disorder, unspecified	0.111	0.888	0.000
I21 Acute myocardial infarction	0.111	0.889	0.000
I61 Intracerebral haemorrhage	0.110	0.890	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.109	0.891	0.000
I10-I15 Hypertensive diseases	0.108	0.892	0.000
I10 Essential (primary) hypertension	0.105	0.895	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.104	0.896	0.000
E89.1 Postprocedural hypoinsulinaemia	0.103	0.897	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.102	0.898	0.000
E70.3 Albinism	0.102	0.898	0.000
E84.8 Cystic fibrosis with other manifestations	0.101	0.898	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.101	0.898	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.101	0.899	0.000
I67.2 Cerebral atherosclerosis	0.101	0.899	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.099	0.901	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.098	0.902	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.097	0.902	0.000
E88.3 Tumour lysis syndrome	0.097	0.903	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.096	0.904	0.000
E50-E64 Other nutritional deficiencies	0.095	0.905	0.000
E89.2 Postprocedural hypoparathyroidism	0.095	0.905	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.094	0.906	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.094	0.906	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.094	0.906	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.093	0.907	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.093	0.907	0.000
I05-I09 Chronic rheumatic heart diseases	0.093	0.907	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.093	0.907	0.000
E89.0 Postprocedural hypothyroidism	0.092	0.908	0.000
E88.2 Lipomatosis, not elsewhere classified	0.091	0.908	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.091	0.909	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.091	0.909	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.090	0.910	0.000
I21.4 Acute subendocardial myocardial infarction	0.090	0.910	0.000
E88.8 Other specified metabolic disorders	0.088	0.912	0.000
I05 Rheumatic mitral valve diseases	0.088	0.912	0.000
I67.5 Moyamoya disease	0.087	0.913	0.000
I67.4 Hypertensive encephalopathy	0.087	0.913	0.000
I67.3 Progressive vascular leukoencephalopathy	0.087	0.913	0.000
I13 Hypertensive heart and renal disease	0.085	0.915	0.000
I00-I02 Acute rheumatic fever	0.085	0.915	0.000
E89.5 Postprocedural testicular hypofunction	0.084	0.916	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.084	0.916	0.000
E45 Retarded development following protein-energy malnutrition	0.084	0.916	0.000
E43 Unspecified severe protein-energy malnutrition	0.084	0.916	0.000
E42 Marasmic kwashiorkor	0.084	0.916	0.000
E41 Nutritional marasmus	0.084	0.916	0.000
E40 Kwashiorkor	0.084	0.916	0.000
I05.2 Mitral stenosis with insufficiency	0.084	0.916	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.082	0.917	0.000
E89.4 Postprocedural ovarian failure	0.082	0.918	0.000
I62.1 Nontraumatic extradural haemorrhage	0.080	0.919	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.080	0.920	0.000
E84.9 Cystic fibrosis, unspecified	0.078	0.921	0.001
E65-E68 Obesity and other hyperalimentation	0.077	0.923	0.000
I68.0 Cerebral amyloid angiopathy	0.076	0.923	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.076	0.924	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.074	0.926	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.073	0.927	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.072	0.928	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.071	0.928	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.071	0.928	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.071	0.928	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.070	0.930	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.068	0.931	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.068	0.932	0.000
E63 Other nutritional deficiencies	0.068	0.932	0.000
E50 Vitamin A deficiency	0.068	0.932	0.000
E60 Dietary zinc deficiency	0.068	0.932	0.000
E59 Dietary selenium deficiency	0.068	0.932	0.000
E52 Niacin deficiency [pellagra]	0.068	0.932	0.000
E58 Dietary calcium deficiency	0.068	0.932	0.000
I05.9 Mitral valve disease, unspecified	0.068	0.932	0.000
E56 Other vitamin deficiencies	0.068	0.932	0.000
I15 Secondary hypertension	0.068	0.932	0.000
I05.1 Rheumatic mitral insufficiency	0.067	0.933	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.067	0.933	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.067	0.933	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.067	0.933	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.067	0.933	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.067	0.933	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.067	0.933	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.066	0.934	0.000
E51 Thiamine deficiency	0.066	0.934	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.065	0.935	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.065	0.935	0.000
I05.8 Other mitral valve diseases	0.064	0.936	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.064	0.936	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.063	0.936	0.000
I09 Other rheumatic heart diseases	0.063	0.937	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.063	0.937	0.000
E61 Deficiency of other nutrient elements	0.063	0.937	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.062	0.938	0.000
I61.8 Other intracerebral haemorrhage	0.062	0.938	0.000
I05.0 Mitral stenosis	0.062	0.938	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.061	0.939	0.000
I02 Rheumatic chorea	0.061	0.939	0.000
I01 Rheumatic fever with heart involvement	0.061	0.939	0.000
E44.1 Mild protein-energy malnutrition	0.060	0.939	0.000
E44.0 Moderate protein-energy malnutrition	0.060	0.939	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.060	0.940	0.000
E53 Deficiency of other B group vitamins	0.058	0.942	0.000
I07 Rheumatic tricuspid valve diseases	0.057	0.943	0.000
E54 Ascorbic acid deficiency	0.057	0.943	0.000
E55 Vitamin D deficiency	0.057	0.943	0.000
E67 Other hyperalimentation	0.056	0.944	0.000
E68 Sequelae of hyperalimentation	0.056	0.944	0.000
I00 Rheumatic fever without mention of heart involvement	0.055	0.945	0.000
I12 Hypertensive renal disease	0.055	0.945	0.000
I15.2 Hypertension secondary to endocrine disorders	0.055	0.945	0.000
E89.3 Postprocedural hypopituitarism	0.054	0.945	0.000
I11 Hypertensive heart disease	0.053	0.946	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.053	0.947	0.000
I06 Rheumatic aortic valve diseases	0.053	0.947	0.000
E80.4 Gilbert's syndrome	0.052	0.948	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.052	0.948	0.000
E53.9 Vitamin B deficiency, unspecified	0.050	0.950	0.000
E50.9 Vitamin A deficiency, unspecified	0.049	0.951	0.000
E50.8 Other manifestations of vitamin A deficiency	0.049	0.951	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.049	0.951	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.049	0.951	0.000
E50.5 Vitamin A deficiency with night blindness	0.049	0.951	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.049	0.951	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.049	0.951	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.049	0.951	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.049	0.951	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.049	0.951	0.000
E63.9 Nutritional deficiency, unspecified	0.049	0.951	0.000
E63.8 Other specified nutritional deficiencies	0.049	0.951	0.000
E63.1 Imbalance of constituents of food intake	0.049	0.951	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.049	0.951	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.049	0.951	0.000
E64.8 Sequelae of other nutritional deficiencies	0.049	0.951	0.000
E64.3 Sequelae of rickets	0.049	0.951	0.000
E64.2 Sequelae of vitamin C deficiency	0.049	0.951	0.000
E64.1 Sequelae of vitamin A deficiency	0.049	0.951	0.000
E64.0 Sequelae of protein-energy malnutrition	0.049	0.951	0.000
E56.9 Vitamin deficiency, unspecified	0.049	0.951	0.000
E56.8 Deficiency of other vitamins	0.049	0.951	0.000
E56.0 Deficiency of vitamin E	0.049	0.951	0.000
E56.1 Deficiency of vitamin K	0.048	0.952	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.048	0.952	0.000
I63 Cerebral infarction	0.048	0.952	0.000
I15.8 Other secondary hypertension	0.047	0.952	0.000
E51.9 Thiamine deficiency, unspecified	0.047	0.952	0.000
E51.8 Other manifestations of thiamine deficiency	0.047	0.952	0.000
E51.1 Beriberi	0.047	0.952	0.000
E61.2 Magnesium deficiency	0.046	0.954	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.045	0.954	0.000
I08 Multiple valve diseases	0.046	0.954	0.000
I09.8 Other specified rheumatic heart diseases	0.045	0.955	0.000
I09.2 Chronic rheumatic pericarditis	0.045	0.955	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.045	0.955	0.000
I09.0 Rheumatic myocarditis	0.045	0.955	0.000
E61.9 Deficiency of nutrient element, unspecified	0.045	0.955	0.000
E61.8 Deficiency of other specified nutrient elements	0.045	0.955	0.000
E61.7 Deficiency of multiple nutrient elements	0.045	0.955	0.000
E61.6 Vanadium deficiency	0.045	0.955	0.000
E61.5 Molybdenum deficiency	0.045	0.955	0.000
E61.4 Chromium deficiency	0.045	0.955	0.000
E61.3 Manganese deficiency	0.045	0.955	0.000
E61.0 Copper deficiency	0.045	0.955	0.000
E51.2 Wernicke's encephalopathy	0.045	0.955	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.044	0.956	0.000
I15.1 Hypertension secondary to other renal disorders	0.044	0.956	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.044	0.956	0.000
I01.8 Other acute rheumatic heart disease	0.044	0.956	0.000
I01.2 Acute rheumatic myocarditis	0.044	0.956	0.000
I01.1 Acute rheumatic endocarditis	0.044	0.956	0.000
I01.0 Acute rheumatic pericarditis	0.044	0.956	0.000
I02.9 Rheumatic chorea without heart involvement	0.044	0.956	0.000
I02.0 Rheumatic chorea with heart involvement	0.044	0.956	0.000
I15.0 Renovascular hypertension	0.043	0.956	0.000
I65.1 Occlusion and stenosis of basilar artery	0.043	0.956	0.000
I15.9 Seconday hypertension, unspecified	0.042	0.958	0.000
E65 Localised adiposity	0.042	0.958	0.000
E53.1 Pyridoxine deficiency	0.041	0.958	0.000
E53.0 Riboflavin deficiency	0.041	0.958	0.000
I08.8 Other multiple valve diseases	0.042	0.958	0.000
I09.9 Rheumatic heart disease, unspecified	0.041	0.958	0.000
I07.9 Tricuspid valve disease, unspecified	0.041	0.959	0.000
I07.8 Other tricuspid valve diseases	0.041	0.959	0.000
I07.2 Tricuspid stenosis with insufficiency	0.041	0.959	0.000
I07.0 Tricuspid stenosis	0.041	0.959	0.000
E55.0 Rickets, active	0.041	0.959	0.000
E67.8 Other specified hyperalimentation	0.040	0.960	0.000
E67.3 Hypervitaminosis D	0.040	0.960	0.000
E67.2 Megavitamin-B6 syndrome	0.040	0.960	0.000
E67.1 Hypercarotenaemia	0.040	0.960	0.000
E67.0 Hypervitaminosis A	0.040	0.960	0.000
I63.8 Other cerebral infarction	0.040	0.960	0.000
I69 Sequelae of cerebrovascular disease	0.040	0.960	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.040	0.960	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.039	0.961	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.038	0.961	0.000
I06.8 Other rheumatic aortic valve diseases	0.038	0.962	0.000
E61.1 Iron deficiency	0.038	0.962	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.962	0.038
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.962	0.038
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.037	0.963	0.000
I67.8 Other specified cerebrovascular diseases	0.037	0.963	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.963	0.037
I12.0 Hypertensive renal disease with renal failure	0.037	0.963	0.000
T42.4 Benzodiazepines	0.000	0.963	0.037
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.964	0.036
I70-I79 Diseases of arteries, arterioles and capillaries	0.036	0.964	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.965	0.035
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.965	0.035
I69.1 Sequelae of intracerebral haemorrhage	0.035	0.965	0.000
I08.0 Disorders of both mitral and aortic valves	0.035	0.965	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.035	0.965	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.035	0.965	0.000
I08.9 Multiple valve disease, unspecified	0.034	0.966	0.000
I28 Other diseases of pulmonary vessels	0.034	0.966	0.000
E83 Disorders of mineral metabolism	0.034	0.966	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.967	0.033
I78 Diseases of capillaries	0.033	0.967	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.033	0.967	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.033	0.967	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.968	0.032
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.968	0.032
I06.1 Rheumatic aortic insufficiency	0.032	0.968	0.000
I07.1 Tricuspid insufficiency	0.032	0.968	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.969	0.031
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.969	0.030
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.970	0.030
T42.0 Hydantoin derivatives	0.000	0.970	0.030
I78.0 Hereditary haemorrhagic telangiectasia	0.030	0.970	0.000
T40.6 Other and unspecified narcotics	0.000	0.970	0.030
I06.0 Rheumatic aortic stenosis	0.029	0.970	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.970	0.029
E46 Unspecified protein-energy malnutrition	0.028	0.971	0.001
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.971	0.029
E55.9 Vitamin D deficiency, unspecified	0.029	0.971	0.000
T46.1 Calcium-channel blockers	0.000	0.971	0.029
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.971	0.029
E83.9 Disorder of mineral metabolism, unspecified	0.029	0.971	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.971	0.029
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.972	0.028
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.972	0.028
T40.2 Other opioids	0.000	0.972	0.028
E20-E35 Disorders of other endocrine glands	0.028	0.972	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.972	0.028
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.972	0.028
T42.3 Barbiturates	0.000	0.972	0.027
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.972	0.027
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.973	0.027
T42.2 Succinimides and oxazolidinediones	0.000	0.973	0.027
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.027	0.973	0.000
T50.1 Loop [high-ceiling] diuretics	0.000	0.973	0.027
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.973	0.027
I21.9 Acute myocardial infarction, unspecified	0.027	0.973	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.973	0.027
I28.8 Other specified diseases of pulmonary vessels	0.026	0.974	0.000
T38.0 Glucocorticoids and synthetic analogues	0.000	0.974	0.026
T50.7 Analeptics and opioid receptor antagonists	0.000	0.974	0.026
T50.5 Appetite depressants	0.000	0.974	0.026
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.974	0.026
T50.0 Mineralocorticoids and their antagonists	0.000	0.974	0.026
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.974	0.026
I78.1 Naevus, nonneoplastic	0.026	0.974	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.974	0.026
I08.2 Disorders of both aortic and tricuspid valves	0.026	0.974	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.026	0.974	0.000
I70 Atherosclerosis	0.026	0.974	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.974	0.026
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.974	0.026
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.974	0.026
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.974	0.026
T46.7 Peripheral vasodilators	0.000	0.974	0.026
T38.9 Other and unspecified hormone antagonists	0.000	0.974	0.025
T38.7 Androgens and anabolic congeners	0.000	0.974	0.025
T38.4 Oral contraceptives	0.000	0.974	0.025
T38.2 Antithyroid drugs	0.000	0.974	0.025
T40.1 Heroin	0.000	0.975	0.025
T50.4 Drugs affecting uric acid metabolism	0.000	0.975	0.025
I11.0 Hypertensive heart disease with (congestive) heart failure	0.025	0.975	0.001
T40.5 Cocaine	0.000	0.975	0.025
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.025	0.975	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.975	0.025
I78.9 Disease of capillaries, unspecified	0.025	0.975	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.025	0.975	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.975	0.025
T43.6 Psychostimulants with abuse potential	0.000	0.975	0.025
I28.1 Aneurysm of pulmonary artery	0.024	0.975	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.976	0.024
E83.8 Other disorders of mineral metabolism	0.024	0.976	0.000
E83.2 Disorders of zinc metabolism	0.024	0.976	0.000
E83.0 Disorders of copper metabolism	0.024	0.976	0.000
T50.8 Diagnostic agents	0.000	0.976	0.024
I72 Other aneurysm	0.024	0.976	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.976	0.024
T40.8 Lysergide [LSD]	0.000	0.976	0.024
T40.7 Cannabis (derivatives)	0.000	0.976	0.024
T40.3 Methadone	0.000	0.976	0.024
T40.0 Opium	0.000	0.976	0.024

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations