TreeWAS – Variant ID: rs294914

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I44 Atrioventricular and left bundle-branch block	0.000	0.001	0.999
I30-I52 Other forms of heart disease	0.000	0.002	0.998
I42 Cardiomyopathy	0.000	0.003	0.997
I44.7 Left bundle-branch block, unspecified	0.000	0.004	0.996
I49 Other cardiac arrhythmias	0.000	0.023	0.977
I42.0 Dilated cardiomyopathy	0.000	0.024	0.976
I47 Paroxysmal tachycardia	0.000	0.044	0.956
I44.0 Atrioventricular block, first degree	0.000	0.045	0.955
I42.9 Cardiomyopathy, unspecified	0.000	0.048	0.952
I44.1 Atrioventricular block, second degree	0.000	0.048	0.952
I49.3 Ventricular premature depolarisation	0.000	0.060	0.940
I47.1 Supraventricular tachycardia	0.000	0.071	0.929
I42.2 Other hypertrophic cardiomyopathy	0.000	0.122	0.878
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.124	0.876
I33 Acute and subacute endocarditis	0.000	0.149	0.851
I49.4 Other and unspecified premature depolarisation	0.000	0.156	0.844
I49.5 Sick sinus syndrome	0.000	0.163	0.837
I44.2 Atrioventricular block, complete	0.000	0.175	0.825
I44.3 Other and unspecified atrioventricular block	0.000	0.179	0.821
I50 Heart failure	0.000	0.198	0.802
I37 Pulmonary valve disorders	0.000	0.232	0.768
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.243	0.757
I33.0 Acute and subacute infective endocarditis	0.000	0.254	0.746
I30 Acute pericarditis	0.000	0.272	0.728
I49.8 Other specified cardiac arrhythmias	0.000	0.282	0.718
I44.5 Left posterior fascicular block	0.000	0.284	0.716
I44.4 Left anterior fascicular block	0.000	0.284	0.716
I52 Other heart disorders in diseases classified elsewhere	0.000	0.284	0.716
I48 Atrial fibrillation and flutter	0.000	0.284	0.716
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.284	0.716
I41 Myocarditis in diseases classified elsewhere	0.000	0.284	0.716
I40 Acute myocarditis	0.000	0.284	0.716
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.284	0.716
I32 Pericarditis in diseases classified elsewhere	0.000	0.284	0.716
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.285	0.715
I42.6 Alcoholic cardiomyopathy	0.000	0.285	0.715
I42.5 Other restrictive cardiomyopathy	0.000	0.285	0.715
I42.4 Endocardial fibroelastosis	0.000	0.285	0.715
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.285	0.715
I42.8 Other cardiomyopathies	0.000	0.286	0.713
I49.2 Junctional premature depolarisation	0.000	0.300	0.700
I38 Endocarditis, valve unspecified	0.000	0.314	0.686
I47.0 Reentry ventricular arrhythmia	0.000	0.314	0.685
I49.0 Ventricular fibrillation and flutter	0.000	0.324	0.676
I49.1 Atrial premature depolarisation	0.000	0.327	0.673
I46 Cardiac arrest	0.000	0.330	0.670
I50.0 Congestive heart failure	0.000	0.356	0.644
I44.6 Other and unspecified fascicular block	0.000	0.375	0.624
I31 Other diseases of pericardium	0.000	0.377	0.623
I36 Nonrheumatic tricuspid valve disorders	0.000	0.379	0.621
I50.1 Left ventricular failure	0.000	0.388	0.612
I33.9 Acute endocarditis, unspecified	0.000	0.390	0.610
I37.1 Pulmonary valve insufficiency	0.000	0.397	0.602
I30.9 Acute pericarditis, unspecified	0.000	0.425	0.575
I50.9 Heart failure, unspecified	0.000	0.442	0.558
I37.9 Pulmonary valve disorder, unspecified	0.000	0.449	0.550
I37.8 Other pulmonary valve disorders	0.000	0.449	0.550
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.449	0.550
I37.0 Pulmonary valve stenosis	0.000	0.449	0.550
I47.2 Ventricular tachycardia	0.000	0.454	0.546
I46.0 Cardiac arrest with successful resuscitation	0.000	0.458	0.542
I49.9 Cardiac arrhythmia, unspecified	0.000	0.459	0.541
I45 Other conduction disorders	0.000	0.464	0.536
I30.8 Other forms of acute pericarditis	0.000	0.478	0.522
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.478	0.522
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.487	0.513
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.487	0.513
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.487	0.513
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.487	0.513
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.487	0.513
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.487	0.513
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.487	0.513
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.487	0.513
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.487	0.513
I40.9 Acute myocarditis, unspecified	0.000	0.487	0.513
I40.8 Other acute myocarditis	0.000	0.487	0.513
I40.1 Isolated myocarditis	0.000	0.487	0.513
I40.0 Infective myocarditis	0.000	0.487	0.513
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.487	0.513
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.487	0.513
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.487	0.513
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.487	0.513
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.487	0.513
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.487	0.513
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.487	0.513
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.487	0.513
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.487	0.513
I48.4 Atypical atrial flutter	0.000	0.487	0.513
I48.3 Typical atrial flutter	0.000	0.487	0.513
I48.2 Chronic atrial fibrillation	0.000	0.487	0.513
I48.1 Persistent atrial fibrillation	0.000	0.487	0.513
I48.0 Paroxysmal atrial fibrillation	0.000	0.487	0.513
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.487	0.513
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.487	0.513
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.487	0.513
I46.1 Sudden cardiac death, so described	0.000	0.520	0.480
I30.1 Infective pericarditis	0.000	0.534	0.466
I25.1 Atherosclerotic heart disease	0.464	0.536	0.000
I31.8 Other specified diseases of pericardium	0.000	0.553	0.446
I31.2 Haemopericardium, not elsewhere classified	0.000	0.553	0.446
I31.1 Chronic constrictive pericarditis	0.000	0.553	0.446
I31.0 Chronic adhesive pericarditis	0.000	0.553	0.446
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.554	0.445
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.554	0.445
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.554	0.445
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.554	0.445
I20.0 Unstable angina	0.439	0.561	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.561	0.439
I20 Angina pectoris	0.433	0.567	0.000
I20.9 Angina pectoris, unspecified	0.429	0.571	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.576	0.424
I45.5 Other specified heart block	0.000	0.604	0.396
I45.4 Nonspecific intraventricular block	0.000	0.615	0.384
I45.3 Trifascicular block	0.000	0.615	0.384
I45.0 Right fascicular block	0.000	0.615	0.384
I31.9 Disease of pericardium, unspecified	0.000	0.616	0.384
I51 Complications and ill-defined descriptions of heart disease	0.000	0.629	0.371
I25 Chronic ischaemic heart disease	0.365	0.635	0.000
I45.2 Bifascicular block	0.000	0.644	0.356
I20-I25 Ischaemic heart diseases	0.356	0.644	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.649	0.351
I20.1 Angina pectoris with documented spasm	0.341	0.659	0.000
I45.9 Conduction disorder, unspecified	0.000	0.661	0.338
I45.8 Other specified conduction disorders	0.000	0.670	0.330
I51.8 Other ill-defined heart diseases	0.000	0.674	0.326
I46.9 Cardiac arrest, unspecified	0.000	0.678	0.321
I25.9 Chronic ischaemic heart disease, unspecified	0.279	0.721	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.273	0.727	0.000
I45.6 Preexcitation syndrome	0.000	0.729	0.271
I51.0 Cardiac septal defect, acquired	0.000	0.731	0.269
I51.5 Myocardial degeneration	0.000	0.734	0.266
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.734	0.266
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.734	0.266
I25.2 Old myocardial infarction	0.265	0.735	0.000
I25.6 Silent myocardial ischaemia	0.262	0.738	0.000
I23 Certain current complications following acute myocardial infarction	0.255	0.745	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.751	0.248
I35 Nonrheumatic aortic valve disorders	0.000	0.754	0.246
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.754	0.246
I25.4 Coronary artery aneurysm	0.238	0.762	0.000
I51.4 Myocarditis, unspecified	0.000	0.787	0.213
I34 Nonrheumatic mitral valve disorders	0.000	0.789	0.211
Z95.1 Presence of aortocoronary bypass graft	0.202	0.798	0.000
I25.5 Ischaemic cardiomyopathy	0.196	0.804	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.186	0.814	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.186	0.814	0.000
I23.8 Other current complications following acute myocardial infarction	0.183	0.817	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.183	0.817	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.183	0.817	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.183	0.817	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.183	0.817	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.183	0.817	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.183	0.817	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.183	0.817	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.817	0.183
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.822	0.177
I25.3 Aneurysm of heart	0.174	0.825	0.000
I20.8 Other forms of angina pectoris	0.172	0.828	0.000
Z95.4 Presence of other heart-valve replacement	0.172	0.828	0.000
I22 Subsequent myocardial infarction	0.166	0.834	0.000
I35.8 Other aortic valve disorders	0.000	0.839	0.161
Z95.2 Presence of prosthetic heart valve	0.160	0.840	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.848	0.151
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.848	0.151
I51.7 Cardiomegaly	0.000	0.849	0.151
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.001	0.868	0.132
I51.9 Heart disease, unspecified	0.000	0.871	0.129
I24 Other acute ischaemic heart diseases	0.129	0.871	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.127	0.873	0.000
I22.8 Subsequent myocardial infarction of other sites	0.120	0.880	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.119	0.880	0.000
Z95.3 Presence of xenogenic heart valve	0.114	0.886	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.103	0.897	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.098	0.902	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.903	0.097
I22.0 Subsequent myocardial infarction of anterior wall	0.095	0.905	0.000
I24.1 Dressler's syndrome	0.093	0.907	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.084	0.915	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.075	0.925	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.074	0.925	0.001
I34.1 Mitral (valve) prolapse	0.001	0.935	0.064
I21 Acute myocardial infarction	0.048	0.952	0.000
I24.8 Other forms of acute ischaemic heart disease	0.040	0.960	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.962	0.038
I21.3 Acute transmural myocardial infarction of unspecified site	0.036	0.964	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.035	0.965	0.000
I21.9 Acute myocardial infarction, unspecified	0.034	0.966	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.032	0.968	0.000
I21.4 Acute subendocardial myocardial infarction	0.022	0.978	0.000
N81.6 Rectocele	0.000	0.979	0.021
I21.1 Acute transmural myocardial infarction of inferior wall	0.019	0.981	0.000
I35.0 Aortic (valve) stenosis	0.002	0.983	0.016
Z95.0 Presence of cardiac pacemaker	0.017	0.983	0.000
Chapter IX Diseases of the circulatory system	0.010	0.987	0.003
D05.9 Carcinoma in situ of breast, unspecified	0.013	0.987	0.000
N81.5 Vaginal enterocele	0.000	0.988	0.012
N81 Female genital prolapse	0.000	0.989	0.011
I77 Other disorders of arteries and arterioles	0.010	0.990	0.000
I77.1 Stricture of artery	0.010	0.990	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.010	0.990	0.000
I00-I02 Acute rheumatic fever	0.007	0.990	0.002
N81.4 Uterovaginal prolapse, unspecified	0.000	0.991	0.009
I05-I09 Chronic rheumatic heart diseases	0.007	0.991	0.002
I77.9 Disorder of arteries and arterioles, unspecified	0.009	0.991	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.009	0.991	0.000
I77.2 Rupture of artery	0.009	0.991	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.991	0.009
I72 Other aneurysm	0.008	0.991	0.000
I70 Atherosclerosis	0.008	0.992	0.000
I77.6 Arteritis, unspecified	0.008	0.992	0.000
I77.0 Arteriovenous fistula, acquired	0.008	0.992	0.000
N81.0 Female urethrocele	0.000	0.992	0.008
I77.5 Necrosis of artery	0.008	0.992	0.000
I77.4 Coeliac artery compression syndrome	0.008	0.992	0.000
I77.3 Arterial fibromuscular dysplasia	0.008	0.992	0.000
I71 Aortic aneurysm and dissection	0.008	0.992	0.000
I05 Rheumatic mitral valve diseases	0.007	0.992	0.001
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.992	0.008
M19.0 Primary arthrosis of other joints	0.000	0.993	0.007
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.005	0.993	0.002
I02 Rheumatic chorea	0.005	0.993	0.002
I01 Rheumatic fever with heart involvement	0.005	0.993	0.002
I00 Rheumatic fever without mention of heart involvement	0.005	0.993	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.007	0.993	0.000
I72.8 Aneurysm of other specified arteries	0.007	0.993	0.000
I72.4 Aneurysm of artery of lower extremity	0.007	0.993	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.007	0.993	0.000
N23 Unspecified renal colic	0.007	0.993	0.000
I70.0 Atherosclerosis of aorta	0.007	0.993	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.993	0.007
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.993	0.007
I77.8 Other specified disorders of arteries and arterioles	0.007	0.993	0.000
I09 Other rheumatic heart diseases	0.005	0.993	0.002
I06 Rheumatic aortic valve diseases	0.005	0.993	0.002
F31.9 Bipolar affective disorder, unspecified	0.000	0.993	0.007
I70.1 Atherosclerosis of renal artery	0.006	0.993	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.993	0.006
I05.9 Mitral valve disease, unspecified	0.006	0.994	0.000
I72.3 Aneurysm of iliac artery	0.006	0.994	0.000
I74 Arterial embolism and thrombosis	0.006	0.994	0.000
M65.34 Trigger finger-Hand	0.006	0.994	0.000
I72.9 Aneurysm of unspecified site	0.006	0.994	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.006	0.994	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.006	0.994	0.000
I72.2 Aneurysm of renal artery	0.006	0.994	0.000
I72.1 Aneurysm of artery of upper extremity	0.006	0.994	0.000
I72.0 Aneurysm of carotid artery	0.006	0.994	0.000
I05.2 Mitral stenosis with insufficiency	0.006	0.994	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
I70.9 Generalised and unspecified atherosclerosis	0.006	0.994	0.000
I70.8 Atherosclerosis of other arteries	0.006	0.994	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.994	0.006
N81.8 Other female genital prolapse	0.000	0.994	0.006
I05.1 Rheumatic mitral insufficiency	0.006	0.994	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.006	0.994	0.000
I05.0 Mitral stenosis	0.005	0.994	0.001
I07 Rheumatic tricuspid valve diseases	0.004	0.994	0.002
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.994	0.006
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.994	0.006
I71.8 Aortic aneurysm of unspecified site, ruptured	0.006	0.994	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.006	0.994	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.006	0.994	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.006	0.994	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.006	0.994	0.000
I05.8 Other mitral valve diseases	0.005	0.994	0.001
F31 Bipolar affective disorder	0.000	0.994	0.006
I71.0 Dissection of aorta [any part]	0.006	0.994	0.000
I78 Diseases of capillaries	0.005	0.994	0.001
M19.08 Primary arthrosis of other joints (Other)	0.000	0.994	0.005
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.994	0.005
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.994	0.005
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.994	0.005
I28 Other diseases of pulmonary vessels	0.004	0.994	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.005	0.994	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.005	0.995	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.004	0.995	0.001
I01.8 Other acute rheumatic heart disease	0.004	0.995	0.001
I01.2 Acute rheumatic myocarditis	0.004	0.995	0.001
I01.1 Acute rheumatic endocarditis	0.004	0.995	0.001
I01.0 Acute rheumatic pericarditis	0.004	0.995	0.001
I02.9 Rheumatic chorea without heart involvement	0.004	0.995	0.001
I02.0 Rheumatic chorea with heart involvement	0.004	0.995	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.995	0.005
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.005	0.995	0.000
I79.1 Aortitis in diseases classified elsewhere	0.005	0.995	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.005	0.995	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.005	0.995	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.995	0.000
I27 Other pulmonary heart diseases	0.004	0.995	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.995	0.001
I06.8 Other rheumatic aortic valve diseases	0.004	0.995	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.995	0.001
I06.1 Rheumatic aortic insufficiency	0.004	0.995	0.001
I06.0 Rheumatic aortic stenosis	0.004	0.995	0.001
I09.8 Other specified rheumatic heart diseases	0.004	0.995	0.001
I09.2 Chronic rheumatic pericarditis	0.004	0.995	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.004	0.995	0.001
I09.0 Rheumatic myocarditis	0.004	0.995	0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.005	0.995	0.000
I09.9 Rheumatic heart disease, unspecified	0.004	0.995	0.001
I73 Other peripheral vascular diseases	0.005	0.995	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.005	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.005	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.995	0.005
I74.9 Embolism and thrombosis of unspecified artery	0.005	0.995	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.005	0.995	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.005	0.995	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.005	0.995	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.003	0.995	0.002
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.004	0.995	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.004	0.995	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.995	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.995	0.000
I74.5 Embolism and thrombosis of iliac artery	0.005	0.995	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.995	0.005
M65.3 Trigger finger	0.005	0.995	0.000
I07.9 Tricuspid valve disease, unspecified	0.003	0.995	0.002
I07.8 Other tricuspid valve diseases	0.003	0.995	0.002
I07.2 Tricuspid stenosis with insufficiency	0.003	0.995	0.002
I07.0 Tricuspid stenosis	0.003	0.995	0.002
I21.0 Acute transmural myocardial infarction of anterior wall	0.004	0.995	0.001
I84.2 Internal haemorrhoids without complication	0.005	0.995	0.000
K76.8 Other specified diseases of liver	0.004	0.995	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.995	0.005
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
N81.2 Incomplete uterovaginal prolapse	0.000	0.996	0.004
F31.8 Other bipolar affective disorders	0.000	0.996	0.004
F31.7 Bipolar affective disorder, currently in remission	0.000	0.996	0.004
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.004
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.996	0.004
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.001
I78.8 Other diseases of capillaries	0.004	0.996	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.996	0.001
I10-I15 Hypertensive diseases	0.004	0.996	0.001
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
I28.9 Disease of pulmonary vessels, unspecified	0.003	0.996	0.001
I28.8 Other specified diseases of pulmonary vessels	0.003	0.996	0.001
I28.1 Aneurysm of pulmonary artery	0.003	0.996	0.001
I28.0 Arteriovenous fistula of pulmonary vessels	0.003	0.996	0.001
I27.8 Other specified pulmonary heart diseases	0.003	0.996	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.004
I27.1 Kyphoscoliotic heart disease	0.003	0.996	0.001
I27.0 Primary pulmonary hypertension	0.004	0.996	0.001
I73.1 Thromboangiitis obliterans [Buerger]	0.004	0.996	0.000
N20.1 Calculus of ureter	0.004	0.996	0.000
I73.8 Other specified peripheral vascular diseases	0.004	0.996	0.000
N20-N23 Urolithiasis	0.004	0.996	0.000
I60-I69 Cerebrovascular diseases	0.004	0.996	0.000
I07.1 Tricuspid insufficiency	0.002	0.996	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.996	0.004
I26 Pulmonary embolism	0.003	0.996	0.001
I73.9 Peripheral vascular disease, unspecified	0.004	0.996	0.000
M65.39 Trigger finger-Site unspec	0.003	0.996	0.000
M65.38 Trigger finger-Other	0.003	0.996	0.000
M65.37 Trigger finger-Ankle/foot	0.003	0.996	0.000
M65.36 Trigger finger-Lower leg	0.003	0.996	0.000
M65.35 Trigger finger-Pelvic/thigh	0.003	0.996	0.000
M65.33 Trigger finger-Forearm	0.003	0.996	0.000
M65.32 Trigger finger-Upper arm	0.003	0.996	0.000
M65.31 Trigger finger-Shldr region	0.003	0.996	0.000
M65.30 Trigger finger-Mult sites	0.003	0.996	0.000
I11 Hypertensive heart disease	0.003	0.996	0.000
H04.1 Other disorders of lachrymal gland	0.004	0.996	0.000
N20 Calculus of kidney and ureter	0.004	0.996	0.000
M13.94 Arthritis, unspecified (Hand)	0.000	0.996	0.004
I27.9 Pulmonary heart disease, unspecified	0.002	0.996	0.002
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.996	0.002
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.996	0.004
I08 Multiple valve diseases	0.001	0.996	0.002
H00.1 Chalazion	0.003	0.997	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.002	0.997	0.002
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.997	0.003
I99 Other and unspecified disorders of circulatory system	0.002	0.997	0.002
I13 Hypertensive heart and renal disease	0.003	0.997	0.001
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
I15 Secondary hypertension	0.003	0.997	0.001
I11.0 Hypertensive heart disease with (congestive) heart failure	0.003	0.997	0.000
D05 Carcinoma in situ of breast	0.003	0.997	0.000
H04.2 Epiphora	0.003	0.997	0.000
K62.1 Rectal polyp	0.003	0.997	0.000
M65 Synovitis and tenosynovitis	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.997	0.003
I27.2 Other secondary pulmonary hypertension	0.001	0.997	0.002
N20.0 Calculus of kidney	0.003	0.997	0.000
H04 Disorders of lachrymal system	0.003	0.997	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.003	0.997	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.003	0.997	0.000
M65.8 Other synovitis and tenosynovitis	0.003	0.997	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.003	0.997	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.003	0.997	0.000
I78.1 Naevus, nonneoplastic	0.001	0.997	0.002
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.997	0.001
H04.3 Acute and unspecified inflammation of lachrymal passages	0.003	0.997	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.997	0.001
I97.2 Postmastectomy lymphoedema syndrome	0.001	0.997	0.001
I97.0 Postcardiotomy syndrome	0.001	0.997	0.001
H61.0 Perichondritis of external ear	0.000	0.997	0.003
I08.9 Multiple valve disease, unspecified	0.001	0.997	0.002
M65.4 Radial styloid tenosynovitis [de Quervain]	0.003	0.997	0.000
T78.4 Allergy, unspecified	0.003	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.997	0.002
I08.8 Other multiple valve diseases	0.001	0.997	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.001	0.997	0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.997	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.997	0.001
I98.0 Cardiovascular syphilis	0.001	0.997	0.001
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.997	0.003
I69 Sequelae of cerebrovascular disease	0.003	0.997	0.000
N21 Calculus of lower urinary tract	0.003	0.997	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.003	0.997	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.997	0.001
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.997	0.001
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.997	0.001
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.997	0.001
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.997	0.001
I97.1 Other functional disturbances following cardiac surgery	0.001	0.997	0.001
H04.4 Chronic inflammation of lachrymal passages	0.003	0.997	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.002	0.997	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.002	0.997	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.002	0.997	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.002	0.997	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.002	0.997	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.002	0.997	0.000
I62 Other nontraumatic intracranial haemorrhage	0.002	0.997	0.001
I60 Subarachnoid haemorrhage	0.002	0.997	0.000
I15.9 Seconday hypertension, unspecified	0.002	0.997	0.001
I15.8 Other secondary hypertension	0.002	0.997	0.001
I15.2 Hypertension secondary to endocrine disorders	0.002	0.997	0.001
I15.0 Renovascular hypertension	0.002	0.997	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.003	0.997	0.000
H00 Hordeolum and chalazion	0.003	0.997	0.000
D05.7 Other carcinoma in situ of breast	0.002	0.997	0.000
H04.9 Disorder of lachrymal system, unspecified	0.003	0.997	0.000
M65.2 Calcific tendinitis	0.002	0.997	0.000
M65.1 Other infective (teno)synovitis	0.002	0.997	0.000
M65.0 Abscess of tendon sheath	0.002	0.997	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.002	0.997	0.000
I61 Intracerebral haemorrhage	0.002	0.997	0.000
D05.0 Lobular carcinoma in situ	0.002	0.997	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.997	0.000
H20 Iridocyclitis	0.000	0.997	0.002
H04.8 Other disorders of lachrymal system	0.002	0.997	0.000
I15.1 Hypertension secondary to other renal disorders	0.002	0.997	0.001
H04.6 Other changes in lachrymal passages	0.002	0.997	0.000
H04.0 Dacryoadenitis	0.002	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.997	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.997	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.002	0.998	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.002	0.998	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.002	0.998	0.000
I65.1 Occlusion and stenosis of basilar artery	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.002	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.002	0.998	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.002	0.998	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.002	0.998	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.002	0.998	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.998	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.002	0.998	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.002	0.998	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.002	0.998	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.002	0.998	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.002	0.998	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I68.0 Cerebral amyloid angiopathy	0.002	0.998	0.000
N83.2 Other and unspecified ovarian cysts	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
N21.1 Calculus in urethra	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.998	0.001
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
H18.4 Corneal degeneration	0.000	0.998	0.002
I73.0 Raynaud's syndrome	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.000	0.998	0.002
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.002	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.002	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.002	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.002	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.002	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.002	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.002	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.002	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.002	0.998	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.002	0.998	0.000
N21.8 Other lower urinary tract calculus	0.002	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations