TreeWAS – Variant ID: rs3011225

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F32.9 Depressive episode, unspecified	0.000	0.793	0.207
F32 Depressive episode	0.000	0.800	0.200
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.803	0.197
F32.0 Mild depressive episode	0.000	0.818	0.182
F32.1 Moderate depressive episode	0.000	0.828	0.172
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.835	0.165
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.850	0.150
F32.8 Other depressive episodes	0.000	0.859	0.141
F30-F39 Mood [affective] disorders	0.000	0.865	0.135
F31 Bipolar affective disorder	0.000	0.868	0.132
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.871	0.129
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.890	0.110
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.896	0.104
F31.7 Bipolar affective disorder, currently in remission	0.000	0.898	0.102
F34 Persistent mood [affective] disorders	0.000	0.900	0.100
F31.8 Other bipolar affective disorders	0.000	0.903	0.097
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.907	0.093
F38 Other mood [affective] disorders	0.000	0.910	0.090
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.910	0.090
F31.9 Bipolar affective disorder, unspecified	0.000	0.914	0.086
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.914	0.086
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.914	0.085
F33 Recurrent depressive disorder	0.000	0.915	0.085
F39 Unspecified mood [affective] disorder	0.000	0.916	0.084
F30 Manic episode	0.000	0.921	0.079
F34.0 Cyclothymia	0.000	0.926	0.074
F34.1 Dysthymia	0.000	0.928	0.072
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.928	0.072
F34.8 Other persistent mood [affective] disorders	0.000	0.928	0.072
I24.8 Other forms of acute ischaemic heart disease	0.000	0.930	0.070
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.932	0.068
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.934	0.066
F38.1 Other recurrent mood [affective] disorders	0.000	0.935	0.065
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.936	0.064
F33.8 Other recurrent depressive disorders	0.000	0.936	0.063
F38.0 Other single mood [affective] disorders	0.000	0.937	0.063
F38.8 Other specified mood [affective] disorders	0.000	0.940	0.060
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.940	0.060
F30.1 Mania without psychotic symptoms	0.000	0.942	0.057
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.943	0.057
F30.8 Other manic episodes	0.000	0.943	0.056
Z91.5 Personal history of self-harm	0.000	0.944	0.056
I24 Other acute ischaemic heart diseases	0.000	0.945	0.055
F30.9 Manic episode, unspecified	0.000	0.946	0.054
F30.2 Mania with psychotic symptoms	0.000	0.947	0.052
F30.0 Hypomania	0.000	0.954	0.046
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.955	0.045
I20.0 Unstable angina	0.000	0.956	0.044
I24.1 Dressler's syndrome	0.000	0.960	0.040
I20-I25 Ischaemic heart diseases	0.000	0.962	0.038
I20 Angina pectoris	0.000	0.962	0.038
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.964	0.036
I23 Certain current complications following acute myocardial infarction	0.000	0.966	0.034
I23.8 Other current complications following acute myocardial infarction	0.000	0.970	0.030
F33.9 Recurrent depressive disorder, unspecified	0.000	0.973	0.027
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.974	0.026
T40.2 Other opioids	0.000	0.975	0.025
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.975	0.024
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.975	0.024
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.975	0.024
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.975	0.024
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.975	0.024
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.975	0.024
I20.8 Other forms of angina pectoris	0.000	0.976	0.024
Z98.0 Intestinal bypass and anastomosis status	0.024	0.976	0.000
I20.9 Angina pectoris, unspecified	0.000	0.976	0.024
I22 Subsequent myocardial infarction	0.000	0.976	0.024
I21 Acute myocardial infarction	0.000	0.979	0.021
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.980	0.020
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.981	0.019
I22.8 Subsequent myocardial infarction of other sites	0.000	0.981	0.019
S92.00 Fracture of calcaneus (closed)	0.000	0.981	0.019
I20.1 Angina pectoris with documented spasm	0.000	0.983	0.017
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.984	0.016
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.984	0.016
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.985	0.015
I21.9 Acute myocardial infarction, unspecified	0.000	0.985	0.015
I25 Chronic ischaemic heart disease	0.000	0.985	0.015
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.986	0.014
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.986	0.014
I25.4 Coronary artery aneurysm	0.000	0.987	0.013
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.988	0.012
I25.1 Atherosclerotic heart disease	0.000	0.989	0.011
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.989	0.011
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.989	0.011
T17.2 Foreign body in pharynx	0.010	0.990	0.000
S92.0 Fracture of calcaneus	0.000	0.990	0.010
I25.6 Silent myocardial ischaemia	0.000	0.990	0.010
D22.4 Melanocytic naevi of scalp and neck	0.009	0.991	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.991	0.009
I25.5 Ischaemic cardiomyopathy	0.000	0.991	0.009
T40.5 Cocaine	0.000	0.992	0.008
I25.3 Aneurysm of heart	0.000	0.992	0.008
T17 Foreign body in respiratory tract	0.008	0.992	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.992	0.008
T40.6 Other and unspecified narcotics	0.000	0.992	0.008
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.992	0.008
T40.8 Lysergide [LSD]	0.000	0.992	0.008
T40.7 Cannabis (derivatives)	0.000	0.992	0.008
T40.0 Opium	0.000	0.992	0.008
T40.1 Heroin	0.000	0.992	0.008
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.992	0.008
T40.4 Other synthetic narcotics	0.000	0.992	0.008
T17.8 Foreign body in other and multiple parts of respiratory tract	0.008	0.992	0.000
T40.3 Methadone	0.000	0.992	0.007
N86 Erosion and ectropion of cervix uteri	0.007	0.993	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.007	0.993	0.000
C83.3 Large cell (diffuse)	0.007	0.993	0.000
J01.9 Acute sinusitis, unspecified	0.000	0.993	0.007
T17.3 Foreign body in larynx	0.007	0.993	0.000
T17.5 Foreign body in bronchus	0.007	0.993	0.000
S81.9 Open wound of lower leg, part unspecified	0.007	0.993	0.000
K14.9 Disease of tongue, unspecified	0.000	0.994	0.006
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.994	0.006
T17.4 Foreign body in trachea	0.006	0.994	0.000
T17.1 Foreign body in nostril	0.006	0.994	0.000
T17.0 Foreign body in nasal sinus	0.006	0.994	0.000
D22.5 Melanocytic naevi of trunk	0.006	0.994	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.994	0.006
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.994	0.006
I31.3 Pericardial effusion (noninflammatory)	0.000	0.994	0.006
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.006	0.994	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.994	0.006
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.994	0.005
D22.7 Melanocytic naevi of lower limb, including hip	0.006	0.994	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.005	0.995	0.000
Z82.2 Family history of deafness and hearing loss	0.000	0.995	0.005
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.995	0.005
S81.0 Open wound of knee	0.005	0.995	0.000
D22 Melanocytic naevi	0.005	0.995	0.000
Z82.1 Family history of blindness and visual loss	0.000	0.995	0.005
S81 Open wound of lower leg	0.005	0.995	0.000
D41.4 Bladder	0.005	0.995	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.005	0.995	0.000
T93 Sequelae of injuries of lower limb	0.004	0.996	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.996	0.004
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.996	0.004
R22.1 Localised swelling, mass and lump, neck	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.004	0.996	0.000
D22.9 Melanocytic naevi, unspecified	0.004	0.996	0.000
S81.8 Open wound of other parts of lower leg	0.004	0.996	0.000
Z82.3 Family history of stroke	0.000	0.996	0.004
D22.6 Melanocytic naevi of upper limb, including shoulder	0.004	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.996	0.000
T93.1 Sequelae of fracture of femur	0.003	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.000	0.997	0.003
K35 Acute appendicitis	0.000	0.997	0.003
R22.2 Localised swelling, mass and lump, trunk	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.003	0.997	0.000
F22.0 Delusional disorder	0.003	0.997	0.000
I25.2 Old myocardial infarction	0.000	0.997	0.003
S81.7 Multiple open wounds of lower leg	0.003	0.997	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.997	0.003
S92.4 Fracture of great toe	0.000	0.997	0.003
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.997	0.003
L40.0 Psoriasis vulgaris	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.997	0.003
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.997	0.003
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.000	0.997	0.003
D22.2 Melanocytic naevi of ear and external auricular canal	0.003	0.997	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.000	0.997	0.003
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
B17.1 Acute hepatitis C	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.997	0.003
S30.1 Contusion of abdominal wall	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.000	0.997	0.003
J01 Acute sinusitis	0.000	0.997	0.003
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.000	0.997	0.002
T90 Sequelae of injuries of head	0.003	0.997	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.997	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.997	0.003
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.997	0.000
L40.5 Arthropathic psoriasis	0.003	0.997	0.000
T90.5 Sequelae of intracranial injury	0.002	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.997	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.000	0.997	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.000	0.998	0.002
Z71.3 Dietary counselling and surveillance	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
K14 Diseases of tongue	0.000	0.998	0.002
C83.7 Burkitt's tumour	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S92.5 Fracture of other toe	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.000	0.998	0.002
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.002	0.998	0.000
S92.1 Fracture of talus	0.000	0.998	0.002
H44.2 Degenerative myopia	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.002	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.998	0.000
J01.8 Other acute sinusitis	0.000	0.998	0.002
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.002
J01.1 Acute frontal sinusitis	0.000	0.998	0.002
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
J01.3 Acute sphenoidal sinusitis	0.000	0.998	0.002
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
L40 Psoriasis	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.002
J01.2 Acute ethmoidal sinusitis	0.000	0.998	0.002
K75.0 Abscess of liver	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
Z91.7 Personal history of female genital mutilation	0.000	0.998	0.002
Z91.3 Personal history of unhealthy sleep-wake schedule	0.000	0.998	0.002
I31 Other diseases of pericardium	0.000	0.998	0.002
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
N76.4 Abscess of vulva	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.002
J01.0 Acute maxillary sinusitis	0.000	0.998	0.002
L40.8 Other psoriasis	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.000	0.998	0.002
I84.0 Internal thrombosed haemorrhoids	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.000	0.998	0.002
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.998	0.002
S30.2 Contusion of external genital organs	0.002	0.998	0.000
Z91.2 Personal history of poor personal hygiene	0.000	0.998	0.002
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
K14.5 Plicated tongue	0.000	0.998	0.002
K14.4 Atrophy of tongue papillae	0.000	0.998	0.002
K14.2 Median rhomboid glossitis	0.000	0.998	0.002
B18 Chronic viral hepatitis	0.000	0.998	0.002
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
K14.1 Geographic tongue	0.000	0.998	0.002
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.000	0.998	0.002
K14.6 Glossodynia	0.000	0.998	0.002
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Z72.9 Problem related to lifestyle, unspecified	0.000	0.998	0.002
Z75 Problems related to medical facilities and other health care	0.000	0.998	0.002
N20.1 Calculus of ureter	0.000	0.998	0.002
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.002
Z72.0 Tobacco use	0.000	0.998	0.002
Z98 Other postsurgical states	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.998	0.002
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
J01.4 Acute pansinusitis	0.000	0.998	0.002
L40.1 Generalised pustular psoriasis	0.002	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.000	0.998	0.002
M75.1 Rotator cuff syndrome	0.000	0.998	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
N32.9 Bladder disorder, unspecified	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
Z70-Z76 Persons encountering health services in other circumstances	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.000	0.998	0.001
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
Z72 Problems related to lifestyle	0.000	0.998	0.002
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.998	0.002
T94.0 Sequelae of injuries involving multiple body regions	0.002	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.002	0.998	0.000
Z75.0 Medical services not available in home	0.000	0.998	0.002
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.998	0.002
D22.0 Melanocytic naevi of lip	0.001	0.998	0.001
D41.0 Kidney	0.002	0.998	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
L40.4 Guttate psoriasis	0.002	0.998	0.000
L40.3 Pustulosis palmaris et plantaris	0.002	0.998	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.002	0.998	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.002	0.998	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
K14.3 Hypertrophy of tongue papillae	0.000	0.998	0.002
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.002	0.998	0.000
B17 Other acute viral hepatitis	0.000	0.998	0.002
Z70 Counselling related to sexual attitude, behaviour and orientation	0.000	0.998	0.002
L40.2 Acrodermatitis continua	0.002	0.998	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.000	0.998	0.002
R22.7 Localised swelling, mass and lump, multiple sites	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
I31.8 Other specified diseases of pericardium	0.000	0.998	0.002
I31.2 Haemopericardium, not elsewhere classified	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
Z72.4 Inappropriate diet and eating habits	0.000	0.998	0.002
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.998	0.002
S92.51 Fracture of other toe (open)	0.000	0.998	0.001
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
Z73.5 Social role conflict, not elsewhere classified	0.000	0.998	0.002
Z73.4 Inadequate social skills, not elsewhere classified	0.000	0.998	0.002
Z73.2 Lack of relaxation and leisure	0.000	0.998	0.002
Z73.1 Accentuation of personality traits	0.000	0.998	0.002
Z73.0 Burn-out	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
B18.8 Other chronic viral hepatitis	0.000	0.998	0.002
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.998	0.002
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
I31.1 Chronic constrictive pericarditis	0.000	0.998	0.002
N76.2 Acute vulvitis	0.000	0.998	0.002
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.001	0.998	0.000
Z72.8 Other problems related to lifestyle	0.000	0.998	0.002
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.998	0.001
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.998	0.002
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.998	0.002
D41.2 Ureter	0.002	0.998	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.998	0.002
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.000	0.998	0.002
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.001
B18.9 Chronic viral hepatitis, unspecified	0.000	0.998	0.001
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.998	0.000
K75.4 Autoimmune hepatitis	0.002	0.998	0.000
O26.2 Pregnancy care of habitual aborter	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.998	0.002
R59.0 Localised enlarged lymph nodes	0.000	0.998	0.002
Z72.6 Gambling and betting	0.000	0.998	0.002
B17.9 Acute viral hepatitis, unspecified	0.000	0.998	0.001
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.998	0.002
O47.9 False labour, unspecified	0.002	0.998	0.000
Z72.5 High-risk sexual behaviour	0.000	0.998	0.002
Z72.3 Lack of physical exercise	0.000	0.998	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
T15 Foreign body on external eye	0.001	0.998	0.000
Z74 Problems related to care-provider dependency	0.000	0.998	0.002
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.998	0.002
B17.2 Acute hepatitis E	0.000	0.998	0.001
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
O62.0 Primary inadequate contractions	0.002	0.998	0.000
Z75.5 Holiday relief care	0.000	0.998	0.002
T16 Foreign body in ear	0.001	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.998	0.001
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.001
S90.0 Contusion of ankle	0.000	0.998	0.001
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
Z70.9 Sex counselling, unspecified	0.000	0.998	0.001
Z70.8 Other sex counselling	0.000	0.998	0.001
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.000	0.998	0.001
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.000	0.998	0.001
Z70.0 Counselling related to sexual attitude	0.000	0.998	0.001
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.001
M21.4 Flat foot [pes planus] (acquired)	0.000	0.998	0.002
D41.1 Renal pelvis	0.001	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
Z72.2 Drug use	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.001	0.998	0.001
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
Z71.6 Tobacco abuse counselling	0.000	0.998	0.002
Z75.8 Other problems related to medical facilities and other health care	0.000	0.998	0.001
H27.8 Other specified disorders of lens	0.002	0.998	0.000
J45.0 Predominantly allergic asthma	0.000	0.998	0.002
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.001	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.001	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.001	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.001	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.001	0.998	0.000
Z74.0 Reduced mobility	0.000	0.998	0.002
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.001	0.998	0.000
K75 Other inflammatory liver diseases	0.002	0.998	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.001	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.001	0.998	0.000
O34.3 Maternal care for cervical incompetence	0.001	0.998	0.000
T15.0 Foreign body in cornea	0.001	0.998	0.000
T18.5 Foreign body in anus and rectum	0.000	0.998	0.001
Z75.2 Other waiting period for investigation and treatment	0.000	0.998	0.001
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.998	0.000
L28.0 Lichen simplex chronicus	0.001	0.998	0.000
M05.2 Rheumatoid vasculitis	0.001	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.998	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.001
Z85.6 Personal history of leukaemia	0.000	0.998	0.001
M05.88 Other seropositive rheumatoid arthritis (Other)	0.001	0.999	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.001	0.999	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.999	0.000
O34.1 Maternal care for tumour of corpus uteri	0.001	0.999	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.001	0.999	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.999	0.001
B17.8 Other specified acute viral hepatitis	0.000	0.999	0.001
G82.5 Tetraplegia, unspecified	0.000	0.999	0.001
I31.0 Chronic adhesive pericarditis	0.000	0.999	0.001
M05.0 Felty's syndrome	0.001	0.999	0.000
O26.0 Excessive weight gain in pregnancy	0.001	0.999	0.000
O62.1 Secondary uterine inertia	0.001	0.999	0.000
Z99.8 Dependence on other enabling machines and devices	0.001	0.999	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.001	0.999	0.000
N20.9 Urinary calculus, unspecified	0.000	0.999	0.001
O26.8 Other specified pregnancy-related conditions	0.001	0.999	0.000
O26.4 Herpes gestationis	0.001	0.999	0.000
O26.1 Low weight gain in pregnancy	0.001	0.999	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.001	0.999	0.000
O75.9 Complication of labour and delivery, unspecified	0.001	0.999	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.001	0.999	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.999	0.001
Z71.5 Drug abuse counselling and surveillance	0.000	0.999	0.001
Z71.0 Person consulting on behalf of another person	0.000	0.999	0.001
Q18 Other congenital malformations of face and neck	0.000	0.999	0.001
T19 Foreign body in genito-urinary tract	0.001	0.999	0.000
Z76 Persons encountering health services in other circumstances	0.000	0.999	0.001
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
T15.9 Foreign body on external eye, unspecified	0.001	0.999	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.999	0.001
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.999	0.001
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.999	0.001
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.999	0.001
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.999	0.001
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.999	0.001
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.999	0.001
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.999	0.001
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.999	0.001
S82.60 Fracture of lateral malleolus (closed)	0.001	0.999	0.000
M05.1 Rheumatoid lung disease	0.001	0.999	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.999	0.001
T91.2 Sequelae of other fracture of thorax and pelvis	0.001	0.999	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.999	0.001
O62 Abnormalities of forces of labour	0.001	0.999	0.000
M24.0 Loose body in joint	0.001	0.999	0.000
O26.5 Maternal hypotension syndrome	0.001	0.999	0.000
O34.6 Maternal care for abnormality of vagina	0.001	0.999	0.000
T15.1 Foreign body in conjunctival sac	0.001	0.999	0.000
S37 Injury of urinary and pelvic organs	0.001	0.999	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.999	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.001	0.999	0.000
N21.8 Other lower urinary tract calculus	0.000	0.999	0.001
S37.3 Injury of urethra	0.001	0.999	0.000
S37.0 Injury of kidney	0.001	0.999	0.000
T90.4 Sequelae of injury of eye and orbit	0.001	0.999	0.000
Z74.1 Need for assistance with personal care	0.000	0.999	0.001
G35 Multiple sclerosis	0.000	0.999	0.001
S90-S99 Injuries to the ankle and foot	0.000	0.999	0.001
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.999	0.000
K75.2 Nonspecific reactive hepatitis	0.001	0.999	0.000
K75.1 Phlebitis of portal vein	0.001	0.999	0.000
O34.0 Maternal care for congenital malformation of uterus	0.001	0.999	0.000
W25.9 Unspecified place	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations