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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3016014
log Bayes Factor = 66.7798
Chromosome 6   position 31,351,153  (GRCh37) Explore rs3016014 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
E16.2 Hypoglycaemia, unspecified
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.005 0.995
E14 Unspecified diabetes mellitus
0.000 0.009 0.991
E10.4 With neurological complications
0.000 0.036 0.964
E11.9 Without complications
0.000 0.039 0.961
E10.2 With renal complications
0.000 0.040 0.960
E14.3 With ophthalmic complications
0.000 0.041 0.959
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.042 0.958
E11.1 With ketoacidosis
0.000 0.078 0.922
E10.8 With unspecified complications
0.000 0.091 0.909
E11.0 With coma
0.000 0.122 0.878
L40-L45 Papulosquamous disorders
0.000 0.135 0.865
E14.8 With unspecified complications
0.000 0.137 0.863
M45 Ankylosing spondylitis
0.000 0.144 0.856
L40.0 Psoriasis vulgaris
0.000 0.144 0.856
E10.5 With peripheral circulatory complications
0.000 0.150 0.850
E14.9 Without complications
0.000 0.156 0.844
E11.4 With neurological complications
0.000 0.164 0.836
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.165 0.835
L43 Lichen planus
0.000 0.166 0.834
E06 Thyroiditis
0.000 0.173 0.827
K51 Ulcerative colitis
0.808 0.192 0.000
E05.8 Other thyrotoxicosis
0.000 0.194 0.806
E11.3 With ophthalmic complications
0.000 0.195 0.805
K51.9 Ulcerative colitis, unspecified
0.803 0.197 0.000
L43.9 Lichen planus, unspecified
0.000 0.200 0.800
E11.5 With peripheral circulatory complications
0.000 0.201 0.799
K51.4 Pseudopolyposis of colon
0.786 0.214 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.217 0.783
L40.1 Generalised pustular psoriasis
0.000 0.219 0.781
L40.8 Other psoriasis
0.000 0.222 0.778
E10.6 With other specified complications
0.000 0.224 0.776
E11.6 With other specified complications
0.000 0.225 0.775
K51.3 Ulcerative (chronic) rectosigmoiditis
0.772 0.228 0.000
K51.8 Other ulcerative colitis
0.770 0.230 0.000
E50-E64 Other nutritional deficiencies
0.000 0.239 0.761
E11.2 With renal complications
0.000 0.245 0.755
E14.4 With neurological complications
0.000 0.249 0.751
E16.1 Other hypoglycaemia
0.000 0.252 0.748
L40.3 Pustulosis palmaris et plantaris
0.000 0.257 0.743
E14.6 With other specified complications
0.000 0.264 0.736
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
E11.7 With multiple complications
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E06.9 Thyroiditis, unspecified
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
E40-E46 Malnutrition
0.000 0.287 0.713
E14.7 With multiple complications
0.000 0.289 0.710
E14.2 Withrenal complications
0.000 0.289 0.710
E14.1 With ketoacidosis
0.000 0.289 0.710
E14.0 With coma
0.000 0.289 0.710
E10.0 With coma
0.000 0.309 0.690
E14.5 With peripheral circulatory complications
0.000 0.315 0.685
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.319 0.681
L43.8 Other lichen planus
0.000 0.320 0.680
E61 Deficiency of other nutrient elements
0.000 0.322 0.678
E11.8 With unspecified complications
0.000 0.323 0.677
K51.5 Mucosal proctocolitis
0.669 0.331 0.000
E13 Other specified diabetes mellitus
0.000 0.339 0.660
L42 Pityriasis rosea
0.000 0.349 0.651
E61.1 Iron deficiency
0.000 0.373 0.627
K51.0 Ulcerative (chronic) enterocolitis
0.622 0.377 0.000
L44 Other papulosquamous disorders
0.000 0.380 0.620
L41 Parapsoriasis
0.000 0.380 0.620
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.380 0.620
E20-E35 Disorders of other endocrine glands
0.000 0.385 0.615
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.386 0.614
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.386 0.614
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.386 0.614
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.386 0.614
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.386 0.614
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.386 0.614
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.386 0.614
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.388 0.612
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.394 0.606
E06.5 Other chronic thyroiditis
0.000 0.397 0.602
K51.1 Ulcerative (chronic) ileocolitis
0.601 0.399 0.000
L43.3 Subacute (active) lichen planus
0.000 0.402 0.598
L43.2 Lichenoid drug reaction
0.000 0.402 0.598
L43.1 Bullous lichen planus
0.000 0.402 0.598
L43.0 Hypertrophic lichen planus
0.000 0.402 0.598
E58 Dietary calcium deficiency
0.000 0.403 0.597
E06.4 Drug-induced thyroiditis
0.000 0.407 0.593
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.407 0.593
E06.1 Subacute thyroiditis
0.000 0.407 0.593
E06.0 Acute thyroiditis
0.000 0.407 0.593
E65-E68 Obesity and other hyperalimentation
0.000 0.414 0.586
E07 Other disorders of thyroid
0.000 0.434 0.566
E24 Cushing's syndrome
0.000 0.434 0.566
E06.3 Autoimmune thyroiditis
0.000 0.442 0.558
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.454 0.545
E63 Other nutritional deficiencies
0.000 0.454 0.545
E51 Thiamine deficiency
0.000 0.454 0.545
E50 Vitamin A deficiency
0.000 0.454 0.545
E60 Dietary zinc deficiency
0.000 0.454 0.545
E59 Dietary selenium deficiency
0.000 0.454 0.545
E54 Ascorbic acid deficiency
0.000 0.454 0.545
E52 Niacin deficiency [pellagra]
0.000 0.454 0.545
K51.2 Ulcerative (chronic) proctitis
0.541 0.459 0.000
E56 Other vitamin deficiencies
0.000 0.464 0.536
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.489 0.511
E45 Retarded development following protein-energy malnutrition
0.000 0.489 0.511
E43 Unspecified severe protein-energy malnutrition
0.000 0.489 0.511
E42 Marasmic kwashiorkor
0.000 0.489 0.511
E41 Nutritional marasmus
0.000 0.489 0.511
E40 Kwashiorkor
0.000 0.489 0.511
E46 Unspecified protein-energy malnutrition
0.000 0.493 0.507
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.502 0.498
E23 Hypofunction and other disorders of pituitary gland
0.000 0.508 0.492
E55 Vitamin D deficiency
0.000 0.511 0.489
E13.3 With ophthalmic complications
0.000 0.511 0.489
E61.9 Deficiency of nutrient element, unspecified
0.000 0.514 0.486
E61.8 Deficiency of other specified nutrient elements
0.000 0.514 0.486
E61.7 Deficiency of multiple nutrient elements
0.000 0.514 0.486
E61.6 Vanadium deficiency
0.000 0.514 0.486
E61.5 Molybdenum deficiency
0.000 0.514 0.486
E61.4 Chromium deficiency
0.000 0.514 0.486
E61.3 Manganese deficiency
0.000 0.514 0.486
E61.0 Copper deficiency
0.000 0.514 0.486
E24.0 Pituitary-dependent Cushing's disease
0.000 0.514 0.486
E13.8 With unspecified complications
0.000 0.526 0.474
E13.7 With multiple complications
0.000 0.526 0.474
E13.6 With other specified complications
0.000 0.526 0.474
E13.5 With peripheral circulatory complications
0.000 0.526 0.474
E13.4 With neurological complications
0.000 0.526 0.474
E13.2 With renal complications
0.000 0.526 0.474
E13.1 With ketoacidosis
0.000 0.526 0.474
E13.0 With coma
0.000 0.526 0.474
E26 Hyperaldosteronism
0.000 0.527 0.473
E24.9 Cushing's syndrome, unspecified
0.000 0.536 0.464
E61.2 Magnesium deficiency
0.000 0.540 0.460
E24.2 Drug-induced Cushing's syndrome
0.000 0.547 0.453
L41.9 Parapsoriasis, unspecified
0.000 0.555 0.445
L41.8 Other parapsoriasis
0.000 0.555 0.445
L41.5 Retiform parapsoriasis
0.000 0.555 0.445
L41.4 Large plaque parapsoriasis
0.000 0.555 0.445
L41.3 Small plaque parapsoriasis
0.000 0.555 0.445
L41.2 Lymphomatoid papulosis
0.000 0.555 0.445
L41.1 Pityriasis lichenoides chronica
0.000 0.555 0.445
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.555 0.445
L44.9 Papulosquamous disorder, unspecified
0.000 0.555 0.445
L44.8 Other specified papulosquamous disorders
0.000 0.555 0.445
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.555 0.445
L44.3 Lichen ruber moniliformis
0.000 0.555 0.445
L44.2 Lichen striatus
0.000 0.555 0.445
L44.1 Lichen nitidus
0.000 0.555 0.445
L44.0 Pityriasis rubra pilaris
0.000 0.555 0.445
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.559 0.441
E32 Diseases of thymus
0.000 0.559 0.441
E30 Disorders of puberty, not elsewhere classified
0.000 0.559 0.441
E25 Adrenogenital disorders
0.000 0.559 0.441
E65 Localised adiposity
0.000 0.559 0.441
E23.7 Disorder of pituitary gland, unspecified
0.000 0.565 0.434
E29 Testicular dysfunction
0.000 0.566 0.434
E21.3 Hyperparathyroidism, unspecified
0.000 0.571 0.429
K90 Intestinal malabsorption
0.000 0.571 0.429
E34 Other endocrine disorders
0.000 0.576 0.424
E67 Other hyperalimentation
0.000 0.580 0.420
E68 Sequelae of hyperalimentation
0.000 0.580 0.420
E31 Polyglandular dysfunction
0.000 0.585 0.414
E07.1 Dyshormogenetic goitre
0.000 0.594 0.406
E07.0 Hypersecretion of calcitonin
0.000 0.594 0.406
E24.8 Other Cushing's syndrome
0.000 0.594 0.406
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.594 0.406
E24.3 Ectopic ACTH syndrome
0.000 0.594 0.406
E24.1 Nelson's syndrome
0.000 0.594 0.406
E13.9 Without complications
0.000 0.605 0.395
E50.9 Vitamin A deficiency, unspecified
0.000 0.609 0.391
E50.8 Other manifestations of vitamin A deficiency
0.000 0.609 0.391
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.609 0.391
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.609 0.391
E50.5 Vitamin A deficiency with night blindness
0.000 0.609 0.391
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.609 0.391
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.609 0.391
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.609 0.391
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.609 0.391
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.609 0.391
E51.9 Thiamine deficiency, unspecified
0.000 0.609 0.391
E51.8 Other manifestations of thiamine deficiency
0.000 0.609 0.391
E51.2 Wernicke's encephalopathy
0.000 0.609 0.391
E51.1 Beriberi
0.000 0.609 0.391
E63.9 Nutritional deficiency, unspecified
0.000 0.609 0.391
E63.8 Other specified nutritional deficiencies
0.000 0.609 0.391
E63.1 Imbalance of constituents of food intake
0.000 0.609 0.391
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.609 0.391
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.609 0.391
E64.8 Sequelae of other nutritional deficiencies
0.000 0.609 0.391
E64.3 Sequelae of rickets
0.000 0.609 0.391
E64.2 Sequelae of vitamin C deficiency
0.000 0.609 0.391
E64.1 Sequelae of vitamin A deficiency
0.000 0.609 0.391
E64.0 Sequelae of protein-energy malnutrition
0.000 0.609 0.391
E07.9 Disorder of thyroid, unspecified
0.000 0.611 0.389
E56.9 Vitamin deficiency, unspecified
0.000 0.615 0.384
E56.8 Deficiency of other vitamins
0.000 0.615 0.384
E56.0 Deficiency of vitamin E
0.000 0.615 0.384
E56.1 Deficiency of vitamin K
0.000 0.624 0.375
E26.0 Primary hyperaldosteronism
0.000 0.629 0.371
E22 Hyperfunction of pituitary gland
0.000 0.630 0.370
E44.1 Mild protein-energy malnutrition
0.000 0.633 0.367
E44.0 Moderate protein-energy malnutrition
0.000 0.633 0.367
E23.0 Hypopituitarism
0.000 0.637 0.363
E23.6 Other disorders of pituitary gland
0.000 0.638 0.361
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.642 0.358
E21.4 Other specified disorders of parathyroid gland
0.000 0.642 0.357
E21.2 Other hyperparathyroidism
0.000 0.642 0.357
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.646 0.354
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.647 0.353
E23.1 Drug-induced hypopituitarism
0.000 0.647 0.353
E55.0 Rickets, active
0.000 0.649 0.351
E03 Other hypothyroidism
0.000 0.653 0.347
E26.9 Hyperaldosteronism, unspecified
0.000 0.661 0.339
E26.8 Other hyperaldosteronism
0.000 0.661 0.339
E26.1 Secondary hyperaldosteronism
0.000 0.661 0.339
E20 Hypoparathyroidism
0.000 0.663 0.337
E21.0 Primary hyperparathyroidism
0.000 0.668 0.332
K90.9 Intestinal malabsorption, unspecified
0.000 0.671 0.329
E34.0 Carcinoid syndrome
0.000 0.675 0.325
E25.9 Adrenogenital disorder, unspecified
0.000 0.684 0.316
E25.8 Other adrenogenital disorders
0.000 0.684 0.316
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.684 0.316
E30.9 Disorder of puberty, unspecified
0.000 0.684 0.316
E30.8 Other disorders of puberty
0.000 0.684 0.316
E30.1 Precocious puberty
0.000 0.684 0.316
E30.0 Delayed puberty
0.000 0.684 0.316
E32.9 Disease of thymus, unspecified
0.000 0.684 0.316
E32.8 Other diseases of thymus
0.000 0.684 0.316
E32.1 Abscess of thymus
0.000 0.684 0.316
E32.0 Persistent hyperplasia of thymus
0.000 0.684 0.316
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.684 0.316
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.684 0.316
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.684 0.316
E53 Deficiency of other B group vitamins
0.000 0.686 0.313
E28 Ovarian dysfunction
0.000 0.688 0.312
E29.9 Testicular dysfunction, unspecified
0.000 0.688 0.311
E29.8 Other testicular dysfunction
0.000 0.688 0.311
E29.0 Testicular hyperfunction
0.000 0.688 0.311
K90.3 Pancreatic steatorrhoea
0.000 0.692 0.308
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.692 0.308
K90.1 Tropical sprue
0.000 0.692 0.308
E29.1 Testicular hypofunction
0.000 0.695 0.305
E34.5 Androgen resistance syndrome
0.000 0.696 0.304
E34.4 Constitutional tall stature
0.000 0.696 0.304
E34.3 Short stature, not elsewhere classified
0.000 0.696 0.304
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.696 0.304
E34.1 Other hypersecretion of intestinal hormones
0.000 0.696 0.304
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.698 0.302
E67.8 Other specified hyperalimentation
0.000 0.699 0.301
E67.3 Hypervitaminosis D
0.000 0.699 0.301
E67.2 Megavitamin-B6 syndrome
0.000 0.699 0.301
E67.1 Hypercarotenaemia
0.000 0.699 0.301
E67.0 Hypervitaminosis A
0.000 0.699 0.301
E31.9 Polyglandular dysfunction, unspecified
0.000 0.703 0.297
E31.8 Other polyglandular dysfunction
0.000 0.703 0.297
E31.1 Polyglandular hyperfunction
0.000 0.703 0.297
E55.9 Vitamin D deficiency, unspecified
0.000 0.705 0.295
E34.9 Endocrine disorder, unspecified
0.000 0.710 0.290
E07.8 Other specified disorders of thyroid
0.000 0.714 0.286
K90.8 Other intestinal malabsorption
0.000 0.714 0.286
E22.0 Acromegaly and pituitary gigantism
0.000 0.716 0.284
E34.8 Other specified endocrine disorders
0.000 0.725 0.275
E31.0 Autoimmune polyglandular failure
0.000 0.729 0.271
E22.1 Hyperprolactinaemia
0.000 0.733 0.267
E22.8 Other hyperfunction of pituitary gland
0.000 0.735 0.265
E03.5 Myxoedema coma
0.000 0.751 0.249
E03.4 Atrophy of thyroid (acquired)
0.000 0.751 0.249
E03.3 Postinfectious hypothyroidism
0.000 0.751 0.249
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.751 0.249
E66 Obesity
0.000 0.754 0.246
E23.2 Diabetes insipidus
0.000 0.755 0.245
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.757 0.243
E03.1 Congenital hypothyroidism without goitre
0.000 0.757 0.242
E20.8 Other hypoparathyroidism
0.000 0.758 0.242
E20.1 Pseudohypoparathyroidism
0.000 0.758 0.242
E20.0 Idiopathic hypoparathyroidism
0.000 0.758 0.242
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.759 0.241
E03.8 Other specified hypothyroidism
0.000 0.768 0.232
E53.1 Pyridoxine deficiency
0.000 0.775 0.225
E53.0 Riboflavin deficiency
0.000 0.775 0.225
E28.9 Ovarian dysfunction, unspecified
0.000 0.776 0.224
E28.8 Other ovarian dysfunction
0.000 0.776 0.224
E28.1 Androgen excess
0.000 0.776 0.224
E28.0 Oestrogen excess
0.000 0.776 0.224
E70-E90 Metabolic disorders
0.000 0.787 0.213
E53.9 Vitamin B deficiency, unspecified
0.000 0.789 0.211
E28.2 Polycystic ovarian syndrome
0.000 0.793 0.207
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.796 0.204
E78.0 Pure hypercholesterolaemia
0.000 0.800 0.200
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.805 0.195
E66.0 Obesity due to excess calories
0.000 0.806 0.194
E85 Amyloidosis
0.000 0.809 0.191
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.810 0.190
E78.8 Other disorders of lipoprotein metabolism
0.000 0.823 0.177
E66.1 Drug-induced obesity
0.000 0.824 0.176
E78.2 Mixed hyperlipidaemia
0.000 0.824 0.176
E74 Other disorders of carbohydrate metabolism
0.000 0.825 0.175
E85.4 Organ-limited amyloidosis
0.000 0.831 0.169
E85.9 Amyloidosis, unspecified
0.000 0.844 0.156
E79 Disorders of purine and pyrimidine metabolism
0.000 0.844 0.156
H36.0 Diabetic retinopathy
0.000 0.844 0.156
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.845 0.155
E77 Disorders of glycoprotein metabolism
0.000 0.847 0.153
E76 Disorders of glycosaminoglycan metabolism
0.000 0.847 0.153
E72 Other disorders of amino-acid metabolism
0.000 0.847 0.153
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.847 0.153
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.847 0.153
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.847 0.153
E78.6 Lipoprotein deficiency
0.000 0.848 0.152
E70 Disorders of aromatic amino-acid metabolism
0.000 0.850 0.150
E78.1 Pure hyperglyceridaemia
0.000 0.850 0.150
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.852 0.148
E78.3 Hyperchylomicronaemia
0.000 0.853 0.146
E84 Cystic fibrosis
0.000 0.855 0.145
E89.3 Postprocedural hypopituitarism
0.000 0.861 0.139
E20.9 Hypoparathyroidism, unspecified
0.001 0.862 0.137
E85.8 Other amyloidosis
0.000 0.863 0.137
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.863 0.137
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.863 0.137
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.863 0.137
E85.3 Secondary systemic amyloidosis
0.000 0.869 0.131
E27 Other disorders of adrenal gland
0.001 0.870 0.130
E78.4 Other hyperlipidaemia
0.000 0.870 0.130
E28.3 Primary ovarian failure
0.001 0.871 0.129
E83.1 Disorders of iron metabolism
0.128 0.872 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.874 0.126
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.874 0.126
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.874 0.126
E74.2 Disorders of galactose metabolism
0.000 0.874 0.126
E74.1 Disorders of fructose metabolism
0.000 0.874 0.126
E74.0 Glycogen storage disease
0.000 0.874 0.126
E73 Lactose intolerance
0.000 0.879 0.121
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.882 0.118
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.885 0.115
E66.8 Other obesity
0.000 0.885 0.115
E75.5 Other lipid storage disorders
0.000 0.887 0.113
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.888 0.112
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.888 0.112
E79.1 Lesch-Nyhan syndrome
0.000 0.888 0.112
E75.6 Lipid storage disorder, unspecified
0.000 0.889 0.111
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.889 0.111
E75.3 Sphingolipidosis, unspecified
0.000 0.889 0.111
E75.2 Other sphingolipidosis
0.000 0.889 0.111
E75.1 Other gangliosidosis
0.000 0.889 0.111
E75.0 GM2 gangliosidosis
0.000 0.889 0.111
E71.3 Disorders of fatty-acid metabolism
0.000 0.890 0.110
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.890 0.110
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.890 0.110
E71.0 Maple-syrup-urine disease
0.000 0.890 0.110
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.890 0.110
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.890 0.110
E72.5 Disorders of glycine metabolism
0.000 0.890 0.110
E72.4 Disorders of ornithine metabolism
0.000 0.890 0.110
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.890 0.110
E72.2 Disorders of urea cycle metabolism
0.000 0.890 0.110
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.890 0.110
E72.0 Disorders of amino-acid transport
0.000 0.890 0.110
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.890 0.110
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.890 0.110
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.890 0.110
E76.2 Other mucopolysaccharidoses
0.000 0.890 0.110
E76.1 Mucopolysaccharidosis, type II
0.000 0.890 0.110
E76.0 Mucopolysaccharidosis, type I
0.000 0.890 0.110
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.890 0.110
E77.8 Other disorders of glycoprotein metabolism
0.000 0.890 0.110
E77.1 Defects in glycoprotein degradation
0.000 0.890 0.110
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.890 0.110
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.890 0.110
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.890 0.110
E89.5 Postprocedural testicular hypofunction
0.000 0.890 0.110
E89.1 Postprocedural hypoinsulinaemia
0.000 0.890 0.110
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.892 0.108
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.892 0.108
E70.2 Disorders of tyrosine metabolism
0.000 0.892 0.108
E70.1 Other hyperphenylalaninaemias
0.000 0.892 0.108
E70.0 Classical phenylketonuria
0.000 0.892 0.108
E27.9 Disorder of adrenal gland, unspecified
0.000 0.895 0.105
E89.4 Postprocedural ovarian failure
0.000 0.895 0.105
E70.3 Albinism
0.000 0.895 0.105
E84.8 Cystic fibrosis with other manifestations
0.000 0.896 0.104
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.896 0.104
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.896 0.104
C77.9 Lymph node, unspecified
0.101 0.899 0.000
C77.2 Intra-abdominal lymph nodes
0.100 0.900 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.903 0.097
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.097 0.903 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.904 0.096
E27.5 Adrenomedullary hyperfunction
0.001 0.906 0.093
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.906 0.093
E27.0 Other adrenocortical overactivity
0.001 0.906 0.093
C77.8 Lymph nodes of multiple regions
0.091 0.909 0.000
E73.8 Other lactose intolerance
0.000 0.913 0.087
E73.1 Secondary lactase deficiency
0.000 0.913 0.087
E73.0 Congenital lactase deficiency
0.000 0.913 0.087
C77.4 Inguinal and lower limb lymph nodes
0.086 0.914 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.917 0.083
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.918 0.082
M07.3 Other psoriatic arthropathies
0.000 0.919 0.081
E89.2 Postprocedural hypoparathyroidism
0.000 0.919 0.081
E27.8 Other specified disorders of adrenal gland
0.001 0.920 0.080
E04 Other non-toxic goitre
0.000 0.924 0.076
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.925 0.075
H36 Retinal disorders in diseases classified elsewhere
0.000 0.927 0.073
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.927 0.073
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.930 0.070
E80.5 Crigler-Najjar syndrome
0.000 0.930 0.070
E80.3 Defects of catalase and peroxydase
0.000 0.930 0.070
E80.0 Hereditary erythropoietic porphyria
0.000 0.930 0.070
E78.5 Hyperlipidaemia, unspecified
0.000 0.931 0.069
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.931 0.069
C77.0 Lymph nodes of head, face and neck
0.069 0.931 0.000
E88 Other metabolic disorders
0.000 0.932 0.068
E80.2 Other porphyria
0.000 0.932 0.067
E80.6 Other disorders of bilirubin metabolism
0.000 0.933 0.067
E80.1 Porphyria cutanea tarda
0.000 0.936 0.064
E27.1 Primary adrenocortical insufficiency
0.001 0.936 0.063
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.063 0.937 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.937 0.063
E89.0 Postprocedural hypothyroidism
0.000 0.937 0.063
M06.9 Rheumatoid arthritis, unspecified
0.000 0.939 0.061
M07.38 Other psoriatic arthropathies (Other)
0.000 0.941 0.059
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.941 0.059
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.941 0.059
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.941 0.059
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.941 0.059
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.942 0.058
M07 Psoriatic and enteropathic arthropathies
0.000 0.943 0.057
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.945 0.055
E04.8 Other specified non-toxic goitre
0.000 0.945 0.054
E73.9 Lactose intolerance, unspecified
0.000 0.945 0.054
C77.5 Intrapelvic lymph nodes
0.054 0.946 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.946 0.054
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.947 0.053
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.947 0.053
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.947 0.053
E88.9 Metabolic disorder, unspecified
0.000 0.947 0.052
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.948 0.052
K50-K52 Noninfective enteritis and colitis
0.051 0.949 0.000
E83 Disorders of mineral metabolism
0.020 0.949 0.031
M06 Other rheumatoid arthritis
0.000 0.952 0.048
E27.4 Other and unspecified adrenocortical insufficiency
0.001 0.953 0.046
E04.0 Non-toxic diffuse goitre
0.000 0.954 0.046
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.954 0.046
E88.8 Other specified metabolic disorders
0.000 0.955 0.044
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.955 0.045
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.956 0.044
E88.3 Tumour lysis syndrome
0.000 0.957 0.042
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.957 0.043
E88.2 Lipomatosis, not elsewhere classified
0.000 0.958 0.041
M05-M14 Inflammatory polyarthropathies
0.000 0.959 0.041
M07.5 Arthropathy in ulcerative colitis
0.000 0.959 0.041
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.959 0.041
M07.2 Psoriatic spondylitis
0.000 0.959 0.041
M07.1 Arthritis mutilans
0.000 0.959 0.041
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.959 0.041
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.959 0.040

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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