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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094564
log Bayes Factor = 42.297
Chromosome 6   position 29,486,345  (GRCh37) Explore rs3094564 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E10.1 With ketoacidosis
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.027 0.973
E10.2 With renal complications
0.000 0.030 0.970
E11 Non-insulin-dependent diabetes mellitus
0.000 0.051 0.949
E14 Unspecified diabetes mellitus
0.000 0.051 0.949
E13 Other specified diabetes mellitus
0.000 0.061 0.939
E11.2 With renal complications
0.000 0.068 0.932
E10.5 With peripheral circulatory complications
0.000 0.086 0.914
E13.9 Without complications
0.000 0.113 0.887
E10.6 With other specified complications
0.000 0.132 0.868
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.168 0.832
E14.5 With peripheral circulatory complications
0.000 0.175 0.825
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.175 0.825
E16 Other disorders of pancreatic internal secretion
0.000 0.179 0.821
E16.2 Hypoglycaemia, unspecified
0.000 0.189 0.811
E10.0 With coma
0.000 0.211 0.789
E11.5 With peripheral circulatory complications
0.000 0.222 0.778
E11.1 With ketoacidosis
0.000 0.230 0.770
E14.4 With neurological complications
0.000 0.240 0.760
K50 Crohn's disease [regional enteritis]
0.752 0.248 0.000
K51 Ulcerative colitis
0.750 0.250 0.000
K50.9 Crohn's disease, unspecified
0.747 0.253 0.000
E14.3 With ophthalmic complications
0.000 0.254 0.746
E10.8 With unspecified complications
0.000 0.257 0.743
K50-K52 Noninfective enteritis and colitis
0.739 0.261 0.000
E14.6 With other specified complications
0.000 0.262 0.738
K50.0 Crohn's disease of small intestine
0.731 0.269 0.000
E50-E64 Other nutritional deficiencies
0.000 0.270 0.730
K51.9 Ulcerative colitis, unspecified
0.728 0.272 0.000
E14.1 With ketoacidosis
0.000 0.275 0.725
E13.3 With ophthalmic complications
0.000 0.275 0.725
E14.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E16.1 Other hypoglycaemia
0.000 0.288 0.712
E11.0 With coma
0.000 0.296 0.703
K51.4 Pseudopolyposis of colon
0.693 0.307 0.000
K51.2 Ulcerative (chronic) proctitis
0.689 0.311 0.000
E14.9 Without complications
0.000 0.314 0.686
E14.2 Withrenal complications
0.000 0.318 0.682
E11.7 With multiple complications
0.000 0.320 0.680
E14.7 With multiple complications
0.000 0.320 0.680
E14.0 With coma
0.000 0.320 0.680
E11.8 With unspecified complications
0.000 0.326 0.674
E13.8 With unspecified complications
0.000 0.326 0.673
E13.7 With multiple complications
0.000 0.326 0.673
E13.6 With other specified complications
0.000 0.326 0.673
E13.5 With peripheral circulatory complications
0.000 0.326 0.673
E13.4 With neurological complications
0.000 0.326 0.673
E13.2 With renal complications
0.000 0.326 0.673
E13.1 With ketoacidosis
0.000 0.326 0.673
E13.0 With coma
0.000 0.326 0.673
E20-E35 Disorders of other endocrine glands
0.000 0.346 0.654
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.372 0.628
K51.3 Ulcerative (chronic) rectosigmoiditis
0.627 0.373 0.000
E24 Cushing's syndrome
0.000 0.385 0.615
K50.8 Other Crohn's disease
0.614 0.386 0.000
E11.6 With other specified complications
0.000 0.390 0.610
E61 Deficiency of other nutrient elements
0.000 0.393 0.607
E15 Nondiabetic hypoglycaemic coma
0.000 0.408 0.591
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.411 0.588
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.411 0.588
E16.4 Abnormal secretion of gastrin
0.000 0.411 0.588
E16.3 Increased secretion of glucagon
0.000 0.411 0.588
N84.1 Polyp of cervix uteri
0.588 0.412 0.000
K51.8 Other ulcerative colitis
0.585 0.415 0.000
E55 Vitamin D deficiency
0.000 0.418 0.582
K51.5 Mucosal proctocolitis
0.581 0.419 0.000
E51 Thiamine deficiency
0.000 0.431 0.569
E23 Hypofunction and other disorders of pituitary gland
0.000 0.432 0.568
E11.4 With neurological complications
0.000 0.443 0.557
K51.0 Ulcerative (chronic) enterocolitis
0.553 0.447 0.000
E56 Other vitamin deficiencies
0.000 0.450 0.550
E00-E07 Disorders of thyroid gland
0.000 0.452 0.548
E24.9 Cushing's syndrome, unspecified
0.000 0.456 0.544
E53 Deficiency of other B group vitamins
0.000 0.461 0.539
E24.0 Pituitary-dependent Cushing's disease
0.000 0.462 0.538
E61.1 Iron deficiency
0.000 0.465 0.534
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.476 0.524
E63 Other nutritional deficiencies
0.000 0.476 0.524
E50 Vitamin A deficiency
0.000 0.476 0.524
E60 Dietary zinc deficiency
0.000 0.476 0.524
E59 Dietary selenium deficiency
0.000 0.476 0.524
E54 Ascorbic acid deficiency
0.000 0.476 0.524
E52 Niacin deficiency [pellagra]
0.000 0.476 0.524
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E23.0 Hypopituitarism
0.000 0.487 0.513
K51.1 Ulcerative (chronic) ileocolitis
0.511 0.489 0.000
K50.1 Crohn's disease of large intestine
0.505 0.495 0.000
E11.9 Without complications
0.000 0.498 0.502
E40-E46 Malnutrition
0.000 0.508 0.492
E11.3 With ophthalmic complications
0.000 0.509 0.491
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.510 0.490
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.513 0.487
E20 Hypoparathyroidism
0.000 0.514 0.486
E28 Ovarian dysfunction
0.000 0.515 0.485
E07 Other disorders of thyroid
0.000 0.516 0.484
E55.9 Vitamin D deficiency, unspecified
0.000 0.524 0.476
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.531 0.469
E32 Diseases of thymus
0.000 0.531 0.469
E30 Disorders of puberty, not elsewhere classified
0.000 0.531 0.469
E25 Adrenogenital disorders
0.000 0.531 0.469
E58 Dietary calcium deficiency
0.000 0.538 0.461
E24.2 Drug-induced Cushing's syndrome
0.000 0.539 0.461
E51.2 Wernicke's encephalopathy
0.000 0.546 0.454
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.554 0.446
E24.8 Other Cushing's syndrome
0.000 0.559 0.441
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.559 0.441
E24.3 Ectopic ACTH syndrome
0.000 0.559 0.441
E24.1 Nelson's syndrome
0.000 0.559 0.441
E31 Polyglandular dysfunction
0.000 0.563 0.437
E61.9 Deficiency of nutrient element, unspecified
0.000 0.565 0.435
E61.8 Deficiency of other specified nutrient elements
0.000 0.565 0.435
E61.7 Deficiency of multiple nutrient elements
0.000 0.565 0.435
E61.6 Vanadium deficiency
0.000 0.565 0.435
E61.5 Molybdenum deficiency
0.000 0.565 0.435
E61.4 Chromium deficiency
0.000 0.565 0.435
E61.3 Manganese deficiency
0.000 0.565 0.435
E61.0 Copper deficiency
0.000 0.565 0.435
E23.2 Diabetes insipidus
0.000 0.565 0.435
E53.9 Vitamin B deficiency, unspecified
0.000 0.570 0.430
E23.7 Disorder of pituitary gland, unspecified
0.000 0.575 0.425
E56.1 Deficiency of vitamin K
0.000 0.579 0.420
E07.8 Other specified disorders of thyroid
0.000 0.582 0.418
E55.0 Rickets, active
0.000 0.582 0.417
E05.9 Thyrotoxicosis, unspecified
0.000 0.586 0.414
K90 Intestinal malabsorption
0.001 0.589 0.410
E51.9 Thiamine deficiency, unspecified
0.000 0.592 0.408
E51.8 Other manifestations of thiamine deficiency
0.000 0.592 0.408
E51.1 Beriberi
0.000 0.592 0.408
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.593 0.407
E23.1 Drug-induced hypopituitarism
0.000 0.593 0.407
E22 Hyperfunction of pituitary gland
0.000 0.597 0.402
E21.3 Hyperparathyroidism, unspecified
0.000 0.599 0.401
E34 Other endocrine disorders
0.000 0.599 0.401
E29 Testicular dysfunction
0.000 0.602 0.398
E61.2 Magnesium deficiency
0.000 0.602 0.397
E56.9 Vitamin deficiency, unspecified
0.000 0.606 0.394
E56.8 Deficiency of other vitamins
0.000 0.606 0.394
E56.0 Deficiency of vitamin E
0.000 0.606 0.394
E28.3 Primary ovarian failure
0.000 0.607 0.393
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.607 0.393
E00 Congenital iodine-deficiency syndrome
0.000 0.607 0.393
E07.9 Disorder of thyroid, unspecified
0.000 0.611 0.389
E53.1 Pyridoxine deficiency
0.000 0.613 0.386
E53.0 Riboflavin deficiency
0.000 0.613 0.386
E50.9 Vitamin A deficiency, unspecified
0.000 0.624 0.376
E50.8 Other manifestations of vitamin A deficiency
0.000 0.624 0.376
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.624 0.376
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.624 0.376
E50.5 Vitamin A deficiency with night blindness
0.000 0.624 0.376
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.624 0.376
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.624 0.376
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.624 0.376
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.624 0.376
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.624 0.376
E63.9 Nutritional deficiency, unspecified
0.000 0.624 0.376
E63.8 Other specified nutritional deficiencies
0.000 0.624 0.376
E63.1 Imbalance of constituents of food intake
0.000 0.624 0.376
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.624 0.376
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.624 0.376
E64.8 Sequelae of other nutritional deficiencies
0.000 0.624 0.376
E64.3 Sequelae of rickets
0.000 0.624 0.376
E64.2 Sequelae of vitamin C deficiency
0.000 0.624 0.376
E64.1 Sequelae of vitamin A deficiency
0.000 0.624 0.376
E64.0 Sequelae of protein-energy malnutrition
0.000 0.624 0.376
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.630 0.370
E20.9 Hypoparathyroidism, unspecified
0.000 0.634 0.366
E06 Thyroiditis
0.000 0.635 0.365
E26 Hyperaldosteronism
0.000 0.644 0.356
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.647 0.353
E45 Retarded development following protein-energy malnutrition
0.000 0.647 0.353
E43 Unspecified severe protein-energy malnutrition
0.000 0.647 0.353
E42 Marasmic kwashiorkor
0.000 0.647 0.353
E41 Nutritional marasmus
0.000 0.647 0.353
E40 Kwashiorkor
0.000 0.647 0.353
E05.5 Thyroid crisis or storm
0.000 0.649 0.351
E05.4 Thyrotoxicosis factitia
0.000 0.649 0.351
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.649 0.351
E21.4 Other specified disorders of parathyroid gland
0.000 0.651 0.349
E20.8 Other hypoparathyroidism
0.000 0.651 0.349
E20.1 Pseudohypoparathyroidism
0.000 0.651 0.349
E20.0 Idiopathic hypoparathyroidism
0.000 0.651 0.349
E28.9 Ovarian dysfunction, unspecified
0.000 0.652 0.348
E28.8 Other ovarian dysfunction
0.000 0.652 0.348
E28.1 Androgen excess
0.000 0.652 0.348
E28.0 Oestrogen excess
0.000 0.652 0.348
E53.8 Deficiency of other specified B group vitamins
0.000 0.653 0.347
E07.1 Dyshormogenetic goitre
0.000 0.653 0.347
E07.0 Hypersecretion of calcitonin
0.000 0.653 0.347
E05.8 Other thyrotoxicosis
0.000 0.654 0.345
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.660 0.340
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.661 0.339
E21.0 Primary hyperparathyroidism
0.000 0.662 0.338
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.663 0.337
K90.9 Intestinal malabsorption, unspecified
0.000 0.663 0.336
E25.9 Adrenogenital disorder, unspecified
0.000 0.664 0.336
E25.8 Other adrenogenital disorders
0.000 0.664 0.336
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.664 0.336
E30.9 Disorder of puberty, unspecified
0.000 0.664 0.336
E30.8 Other disorders of puberty
0.000 0.664 0.336
E30.1 Precocious puberty
0.000 0.664 0.336
E30.0 Delayed puberty
0.000 0.664 0.336
E32.9 Disease of thymus, unspecified
0.000 0.664 0.336
E32.8 Other diseases of thymus
0.000 0.664 0.336
E32.1 Abscess of thymus
0.000 0.664 0.336
E32.0 Persistent hyperplasia of thymus
0.000 0.664 0.336
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.664 0.336
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.664 0.336
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.664 0.336
E21.2 Other hyperparathyroidism
0.000 0.666 0.334
E34.8 Other specified endocrine disorders
0.000 0.668 0.332
E23.6 Other disorders of pituitary gland
0.000 0.680 0.320
E22.0 Acromegaly and pituitary gigantism
0.000 0.681 0.319
E31.9 Polyglandular dysfunction, unspecified
0.000 0.686 0.313
E31.8 Other polyglandular dysfunction
0.000 0.686 0.313
E31.1 Polyglandular hyperfunction
0.000 0.686 0.313
E65-E68 Obesity and other hyperalimentation
0.000 0.688 0.312
E06.9 Thyroiditis, unspecified
0.000 0.691 0.309
E28.2 Polycystic ovarian syndrome
0.000 0.694 0.306
E27 Other disorders of adrenal gland
0.000 0.703 0.296
K90.8 Other intestinal malabsorption
0.001 0.705 0.295
K90.3 Pancreatic steatorrhoea
0.001 0.705 0.294
K90.2 Blind loop syndrome, not elsewhere classified
0.001 0.705 0.294
K90.1 Tropical sprue
0.001 0.705 0.294
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.711 0.289
E22.8 Other hyperfunction of pituitary gland
0.000 0.711 0.289
E34.5 Androgen resistance syndrome
0.000 0.712 0.287
E34.4 Constitutional tall stature
0.000 0.712 0.287
E34.3 Short stature, not elsewhere classified
0.000 0.712 0.287
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.712 0.287
E34.1 Other hypersecretion of intestinal hormones
0.000 0.712 0.287
E29.9 Testicular dysfunction, unspecified
0.000 0.715 0.285
E29.8 Other testicular dysfunction
0.000 0.715 0.285
E29.0 Testicular hyperfunction
0.000 0.715 0.285
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.718 0.282
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.718 0.282
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.718 0.282
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.718 0.282
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.718 0.282
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.718 0.282
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.718 0.282
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.718 0.282
E31.0 Autoimmune polyglandular failure
0.000 0.718 0.282
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.724 0.276
E27.1 Primary adrenocortical insufficiency
0.000 0.732 0.267
E06.1 Subacute thyroiditis
0.000 0.733 0.267
E06.4 Drug-induced thyroiditis
0.000 0.738 0.262
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.738 0.262
E06.0 Acute thyroiditis
0.000 0.738 0.262
E26.8 Other hyperaldosteronism
0.000 0.744 0.255
E26.1 Secondary hyperaldosteronism
0.000 0.744 0.255
E26.9 Hyperaldosteronism, unspecified
0.000 0.745 0.254
E44.1 Mild protein-energy malnutrition
0.000 0.747 0.253
E44.0 Moderate protein-energy malnutrition
0.000 0.747 0.253
E46 Unspecified protein-energy malnutrition
0.000 0.752 0.248
E22.1 Hyperprolactinaemia
0.000 0.753 0.247
E34.9 Endocrine disorder, unspecified
0.000 0.764 0.236
E67 Other hyperalimentation
0.000 0.776 0.224
E68 Sequelae of hyperalimentation
0.000 0.776 0.224
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.776 0.223
E29.1 Testicular hypofunction
0.000 0.786 0.214
E27.5 Adrenomedullary hyperfunction
0.000 0.787 0.213
E27.0 Other adrenocortical overactivity
0.000 0.787 0.213
E03 Other hypothyroidism
0.000 0.791 0.209
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.792 0.207
E27.8 Other specified disorders of adrenal gland
0.000 0.793 0.207
E06.5 Other chronic thyroiditis
0.000 0.797 0.202
E06.3 Autoimmune thyroiditis
0.000 0.797 0.203
E34.0 Carcinoid syndrome
0.000 0.803 0.196
E65 Localised adiposity
0.000 0.812 0.188
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.820 0.180
E67.8 Other specified hyperalimentation
0.000 0.839 0.160
E67.3 Hypervitaminosis D
0.000 0.839 0.160
E67.2 Megavitamin-B6 syndrome
0.000 0.839 0.160
E67.1 Hypercarotenaemia
0.000 0.839 0.160
E67.0 Hypervitaminosis A
0.000 0.839 0.160
E03.8 Other specified hypothyroidism
0.000 0.840 0.160
E03.1 Congenital hypothyroidism without goitre
0.000 0.840 0.160
E27.9 Disorder of adrenal gland, unspecified
0.000 0.845 0.155
E03.5 Myxoedema coma
0.000 0.850 0.150
E03.4 Atrophy of thyroid (acquired)
0.000 0.850 0.150
E03.3 Postinfectious hypothyroidism
0.000 0.850 0.150
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.850 0.150
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.850 0.149
E26.0 Primary hyperaldosteronism
0.001 0.855 0.145
E27.2 Addisonian crisis
0.001 0.871 0.129
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.889 0.111
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.891 0.108
E04 Other non-toxic goitre
0.000 0.893 0.107
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.906 0.094
E83 Disorders of mineral metabolism
0.087 0.908 0.005
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.908 0.092
E04.9 Non-toxic goitre, unspecified
0.000 0.914 0.086
E04.8 Other specified non-toxic goitre
0.000 0.923 0.077
K52 Other non-infective gastro-enteritis and colitis
0.075 0.924 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.932 0.068
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.932 0.068
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.932 0.068
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.932 0.068
E83.8 Other disorders of mineral metabolism
0.063 0.933 0.004
E83.2 Disorders of zinc metabolism
0.063 0.933 0.004
E83.0 Disorders of copper metabolism
0.063 0.933 0.004
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.935 0.065
E83.9 Disorder of mineral metabolism, unspecified
0.059 0.937 0.004
K52.0 Gastro-enteritis and colitis due to radiation
0.061 0.938 0.000
E83.3 Disorders of phosphorus metabolism
0.057 0.941 0.002
Z99.1 Dependence on respirator
0.000 0.946 0.054
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.049 0.950 0.000
K52.3 Indeterminate colitis
0.047 0.953 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.954 0.045
E66 Obesity
0.000 0.955 0.045
N84 Polyp of female genital tract
0.044 0.956 0.000
K52.1 Toxic gastro-enteritis and colitis
0.039 0.961 0.000
E70-E90 Metabolic disorders
0.000 0.962 0.038
E83.4 Disorders of magnesium metabolism
0.036 0.962 0.002
E73 Lactose intolerance
0.000 0.963 0.037
E73.9 Lactose intolerance, unspecified
0.000 0.963 0.037
N84.9 Polyp of female genital tract, unspecified
0.035 0.965 0.000
J38.3 Other diseases of vocal cords
0.034 0.966 0.000
E66.1 Drug-induced obesity
0.000 0.967 0.033
J38.7 Other diseases of larynx
0.033 0.967 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.033 0.967 0.000
E66.0 Obesity due to excess calories
0.000 0.968 0.031
J38.4 Oedema of larynx
0.031 0.969 0.000
N84.8 Polyp of other parts of female genital tract
0.031 0.969 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.970 0.030
E04.2 Non-toxic multinodular goitre
0.000 0.970 0.030
E79 Disorders of purine and pyrimidine metabolism
0.000 0.970 0.029
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.970 0.029
E84 Cystic fibrosis
0.000 0.971 0.029
Z99.8 Dependence on other enabling machines and devices
0.000 0.971 0.029
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.971 0.029
F45.8 Other somatoform disorders
0.000 0.971 0.029
E77 Disorders of glycoprotein metabolism
0.000 0.972 0.027
E76 Disorders of glycosaminoglycan metabolism
0.000 0.972 0.027
E72 Other disorders of amino-acid metabolism
0.000 0.972 0.027
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.972 0.027
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.972 0.027
J38.5 Laryngeal spasm
0.028 0.972 0.000
K90-K93 Other diseases of the digestive system
0.004 0.972 0.024
E70 Disorders of aromatic amino-acid metabolism
0.000 0.973 0.027
E73.8 Other lactose intolerance
0.000 0.973 0.027
E73.1 Secondary lactase deficiency
0.000 0.973 0.027
E73.0 Congenital lactase deficiency
0.000 0.973 0.027
E85 Amyloidosis
0.000 0.974 0.026
E88 Other metabolic disorders
0.000 0.975 0.025
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.976 0.024
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.976 0.024
J38.2 Nodules of vocal cords
0.024 0.976 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.023 0.977 0.000
E75.5 Other lipid storage disorders
0.000 0.977 0.023
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.977 0.023
E84.9 Cystic fibrosis, unspecified
0.000 0.977 0.023
N84.3 Polyp of vulva
0.022 0.977 0.000
E74.0 Glycogen storage disease
0.000 0.977 0.022
E85.4 Organ-limited amyloidosis
0.000 0.978 0.022
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.978 0.022
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.978 0.022
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.978 0.022
E74.2 Disorders of galactose metabolism
0.000 0.978 0.022
E74.1 Disorders of fructose metabolism
0.000 0.978 0.022
J38.6 Stenosis of larynx
0.022 0.978 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.979 0.021
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.979 0.021
E75.3 Sphingolipidosis, unspecified
0.000 0.979 0.021
E75.2 Other sphingolipidosis
0.000 0.979 0.021
E75.1 Other gangliosidosis
0.000 0.979 0.021
E75.0 GM2 gangliosidosis
0.000 0.979 0.021
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.979 0.021
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.979 0.021
E79.1 Lesch-Nyhan syndrome
0.000 0.979 0.021
N84.2 Polyp of vagina
0.021 0.979 0.000
E83.5 Disorders of calcium metabolism
0.021 0.979 0.001
E84.8 Cystic fibrosis with other manifestations
0.000 0.979 0.021
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.979 0.021
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.979 0.021
K59.8 Other specified functional intestinal disorders
0.021 0.979 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.979 0.021
Z99.4 Dependence on artificial heart
0.000 0.979 0.021
Z99.0 Dependence on aspirator
0.000 0.979 0.021
F45 Somatoform disorders
0.000 0.979 0.021
E04.1 Non-toxic single thyroid nodule
0.000 0.979 0.021
E71.3 Disorders of fatty-acid metabolism
0.000 0.980 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.980 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.980 0.020
E71.0 Maple-syrup-urine disease
0.000 0.980 0.020
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.980 0.020
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.980 0.020
E72.5 Disorders of glycine metabolism
0.000 0.980 0.020
E72.4 Disorders of ornithine metabolism
0.000 0.980 0.020
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.980 0.020
E72.2 Disorders of urea cycle metabolism
0.000 0.980 0.020
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.980 0.020
E72.0 Disorders of amino-acid transport
0.000 0.980 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.980 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.980 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.980 0.020
E76.2 Other mucopolysaccharidoses
0.000 0.980 0.020
E76.1 Mucopolysaccharidosis, type II
0.000 0.980 0.020
E76.0 Mucopolysaccharidosis, type I
0.000 0.980 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.980 0.020
E77.8 Other disorders of glycoprotein metabolism
0.000 0.980 0.020
E77.1 Defects in glycoprotein degradation
0.000 0.980 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.003 0.980 0.017
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.980 0.020
J38.0 Paralysis of vocal cords and larynx
0.020 0.980 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.980 0.019
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.980 0.019
E70.2 Disorders of tyrosine metabolism
0.000 0.980 0.019
E70.1 Other hyperphenylalaninaemias
0.000 0.980 0.019
E70.0 Classical phenylketonuria
0.000 0.980 0.019
E88.2 Lipomatosis, not elsewhere classified
0.000 0.980 0.019
J38.1 Polyp of vocal cord and larynx
0.020 0.980 0.000
L40.9 Psoriasis, unspecified
0.000 0.981 0.019
E70.3 Albinism
0.000 0.981 0.019
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.981 0.019
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.981 0.019
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.981 0.019
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.981 0.019
K40 Inguinal hernia
0.019 0.981 0.000
N00-N08 Glomerular diseases
0.000 0.981 0.019
E88.9 Metabolic disorder, unspecified
0.000 0.981 0.018
K43 Ventral hernia
0.018 0.982 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.018 0.982 0.000
E85.8 Other amyloidosis
0.000 0.982 0.017
F45.9 Somatoform disorder, unspecified
0.000 0.983 0.017
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.983 0.017
F45.2 Hypochondriacal disorder
0.000 0.983 0.017
K43.0 Ventral hernia with obstruction, without gangrene
0.017 0.983 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.983 0.016
E88.3 Tumour lysis syndrome
0.000 0.983 0.016
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.983 0.017
F45.0 Somatisation disorder
0.000 0.983 0.017
K41 Femoral hernia
0.016 0.984 0.000
K40-K46 Hernia
0.016 0.984 0.000
E88.8 Other specified metabolic disorders
0.000 0.984 0.016
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.016 0.984 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.015 0.984 0.000
E66.8 Other obesity
0.000 0.985 0.015
F45.1 Undifferentiated somatoform disorder
0.000 0.985 0.015
E85.9 Amyloidosis, unspecified
0.000 0.985 0.015
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.015 0.985 0.000
E80.6 Other disorders of bilirubin metabolism
0.000 0.985 0.015
M31.6 Other giant cell arteritis
0.000 0.985 0.015
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.002 0.985 0.012
K93.1 Megacolon in Chagas' disease
0.002 0.985 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.002 0.985 0.012
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.985 0.014
E80.5 Crigler-Najjar syndrome
0.000 0.985 0.014
E80.3 Defects of catalase and peroxydase
0.000 0.985 0.014
E80.0 Hereditary erythropoietic porphyria
0.000 0.985 0.014
F45.4 Persistent somatoform pain disorder
0.000 0.986 0.014
N04 Nephrotic syndrome
0.000 0.986 0.014
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.014 0.986 0.000
F45.3 Somatoform autonomic dysfunction
0.000 0.986 0.014
N05 Unspecified nephritic syndrome
0.000 0.986 0.014
K40.1 Bilateral inguinal hernia, with gangrene
0.014 0.986 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.986 0.014
N06 Isolated proteinuria with specified morphological lesion
0.000 0.986 0.014
N01 Rapidly progressive nephritic syndrome
0.000 0.986 0.014
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.013 0.987 0.000
N00 Acute nephritic syndrome
0.000 0.987 0.013
K43.7 Other and unspecified ventral hernia with gangrene
0.013 0.987 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.013 0.987 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.013 0.987 0.000
K43.4 Parastomal hernia with gangrene
0.013 0.987 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.013 0.987 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.013 0.987 0.000
K43.1 Ventral hernia with gangrene
0.013 0.987 0.000
E80.2 Other porphyria
0.000 0.987 0.013
N05.1 Focal and segmental glomerular lesions
0.000 0.987 0.013
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.012 0.987 0.000
E80.1 Porphyria cutanea tarda
0.000 0.987 0.012
Z99.3 Dependence on wheelchair
0.000 0.987 0.013
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.012 0.988 0.000
L40 Psoriasis
0.000 0.988 0.012
K41.1 Bilateral femoral hernia, with gangrene
0.012 0.988 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.012 0.988 0.000
E80.4 Gilbert's syndrome
0.000 0.988 0.012
L40.5 Arthropathic psoriasis
0.000 0.988 0.012
N04.2 Diffuse membranous glomerulonephritis
0.000 0.988 0.012
K46 Unspecified abdominal hernia
0.011 0.989 0.000
F41.1 Generalised anxiety disorder
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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