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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095273
log Bayes Factor = 36.611
Chromosome 6   position 29,566,369  (GRCh37) Explore rs3095273 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.024 0.976
E10.3 With ophthalmic complications
0.000 0.040 0.960
E10.9 Without complications
0.000 0.053 0.947
E10-E14 Diabetes mellitus
0.000 0.062 0.938
E10.4 With neurological complications
0.000 0.088 0.912
E13 Other specified diabetes mellitus
0.000 0.088 0.912
E10.2 With renal complications
0.000 0.097 0.903
E13.9 Without complications
0.000 0.107 0.893
E10.1 With ketoacidosis
0.000 0.141 0.859
E10.0 With coma
0.000 0.166 0.834
E10.6 With other specified complications
0.000 0.181 0.819
E14 Unspecified diabetes mellitus
0.000 0.197 0.803
E10.7 With multiple complications
0.000 0.296 0.704
E14.9 Without complications
0.000 0.296 0.704
E12 Malnutrition-related diabetes mellitus
0.000 0.328 0.672
E10.5 With peripheral circulatory complications
0.000 0.337 0.663
E11 Non-insulin-dependent diabetes mellitus
0.000 0.342 0.658
E13.8 With unspecified complications
0.000 0.346 0.654
E13.7 With multiple complications
0.000 0.346 0.654
E13.6 With other specified complications
0.000 0.346 0.654
E13.5 With peripheral circulatory complications
0.000 0.346 0.654
E13.4 With neurological complications
0.000 0.346 0.654
E13.3 With ophthalmic complications
0.000 0.346 0.654
E13.2 With renal complications
0.000 0.346 0.654
E13.1 With ketoacidosis
0.000 0.346 0.654
E13.0 With coma
0.000 0.346 0.654
E14.1 With ketoacidosis
0.000 0.386 0.614
E14.6 With other specified complications
0.000 0.388 0.612
E11.6 With other specified complications
0.000 0.408 0.592
E14.4 With neurological complications
0.000 0.422 0.578
E14.7 With multiple complications
0.000 0.424 0.576
E14.5 With peripheral circulatory complications
0.000 0.424 0.576
E14.0 With coma
0.000 0.424 0.576
E14.2 Withrenal complications
0.000 0.425 0.575
E14.8 With unspecified complications
0.000 0.442 0.557
E11.1 With ketoacidosis
0.000 0.448 0.551
E11.0 With coma
0.000 0.471 0.529
E14.3 With ophthalmic complications
0.000 0.491 0.509
E11.8 With unspecified complications
0.000 0.491 0.509
E10.8 With unspecified complications
0.000 0.495 0.504
E11.2 With renal complications
0.000 0.495 0.505
E12.9 Without complications
0.000 0.518 0.482
E12.8 With unspecified complications
0.000 0.518 0.482
E12.7 With multiple complications
0.000 0.518 0.482
E12.6 With other specified complications
0.000 0.518 0.482
E12.5 With peripheral circulatory complications
0.000 0.518 0.482
E12.4 With neurological complications
0.000 0.518 0.482
E12.3 With ophthalmic complications
0.000 0.518 0.482
E12.2 With renal complications
0.000 0.518 0.482
E12.1 With ketoacidosis
0.000 0.518 0.482
E12.0 With coma
0.000 0.518 0.482
E11.7 With multiple complications
0.000 0.528 0.472
K51 Ulcerative colitis
0.457 0.543 0.000
K51.9 Ulcerative colitis, unspecified
0.456 0.544 0.000
E11.5 With peripheral circulatory complications
0.000 0.546 0.454
K51.4 Pseudopolyposis of colon
0.444 0.556 0.000
K51.5 Mucosal proctocolitis
0.417 0.583 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.585 0.415
K51.8 Other ulcerative colitis
0.392 0.608 0.000
K51.2 Ulcerative (chronic) proctitis
0.390 0.610 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.611 0.389
E20-E35 Disorders of other endocrine glands
0.000 0.621 0.379
E23 Hypofunction and other disorders of pituitary gland
0.000 0.621 0.379
E16 Other disorders of pancreatic internal secretion
0.000 0.629 0.370
E23.0 Hypopituitarism
0.000 0.632 0.368
K90 Intestinal malabsorption
0.000 0.638 0.362
E16.2 Hypoglycaemia, unspecified
0.000 0.640 0.360
K51.3 Ulcerative (chronic) rectosigmoiditis
0.347 0.653 0.000
E24 Cushing's syndrome
0.000 0.653 0.347
E23.2 Diabetes insipidus
0.000 0.659 0.341
E50-E64 Other nutritional deficiencies
0.000 0.664 0.336
K51.1 Ulcerative (chronic) ileocolitis
0.330 0.670 0.000
E83 Disorders of mineral metabolism
0.324 0.675 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.678 0.322
K51.0 Ulcerative (chronic) enterocolitis
0.306 0.694 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.701 0.299
E16.1 Other hypoglycaemia
0.000 0.706 0.294
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.713 0.287
E11.4 With neurological complications
0.000 0.714 0.286
E23.6 Other disorders of pituitary gland
0.000 0.715 0.285
E25 Adrenogenital disorders
0.000 0.718 0.282
E61 Deficiency of other nutrient elements
0.000 0.720 0.280
E15 Nondiabetic hypoglycaemic coma
0.000 0.721 0.279
E55 Vitamin D deficiency
0.000 0.726 0.273
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.728 0.272
E32 Diseases of thymus
0.000 0.728 0.272
E30 Disorders of puberty, not elsewhere classified
0.000 0.728 0.272
E20 Hypoparathyroidism
0.000 0.728 0.272
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.728 0.272
E23.1 Drug-induced hypopituitarism
0.000 0.728 0.272
E83.4 Disorders of magnesium metabolism
0.268 0.732 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.734 0.266
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.734 0.266
E16.4 Abnormal secretion of gastrin
0.000 0.734 0.266
E16.3 Increased secretion of glucagon
0.000 0.734 0.266
E34 Other endocrine disorders
0.000 0.735 0.265
K90.3 Pancreatic steatorrhoea
0.000 0.740 0.259
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.740 0.259
K90.1 Tropical sprue
0.000 0.740 0.259
K90.8 Other intestinal malabsorption
0.000 0.740 0.259
E24.2 Drug-induced Cushing's syndrome
0.000 0.743 0.257
E26 Hyperaldosteronism
0.000 0.745 0.255
E24.8 Other Cushing's syndrome
0.000 0.751 0.249
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.751 0.249
E24.3 Ectopic ACTH syndrome
0.000 0.751 0.249
E24.1 Nelson's syndrome
0.000 0.751 0.249
E24.0 Pituitary-dependent Cushing's disease
0.000 0.751 0.249
E31 Polyglandular dysfunction
0.000 0.753 0.247
E61.1 Iron deficiency
0.000 0.757 0.243
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.759 0.241
E63 Other nutritional deficiencies
0.000 0.759 0.241
E56 Other vitamin deficiencies
0.000 0.759 0.241
E50 Vitamin A deficiency
0.000 0.759 0.241
E60 Dietary zinc deficiency
0.000 0.759 0.241
E59 Dietary selenium deficiency
0.000 0.759 0.241
E54 Ascorbic acid deficiency
0.000 0.759 0.241
E52 Niacin deficiency [pellagra]
0.000 0.759 0.241
E29 Testicular dysfunction
0.000 0.760 0.240
E51 Thiamine deficiency
0.000 0.760 0.240
E58 Dietary calcium deficiency
0.000 0.766 0.234
E83.3 Disorders of phosphorus metabolism
0.234 0.766 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.233 0.767 0.000
E83.8 Other disorders of mineral metabolism
0.233 0.767 0.000
E83.2 Disorders of zinc metabolism
0.233 0.767 0.000
E83.0 Disorders of copper metabolism
0.233 0.767 0.000
E40-E46 Malnutrition
0.000 0.768 0.232
E11.3 With ophthalmic complications
0.000 0.769 0.231
E55.9 Vitamin D deficiency, unspecified
0.000 0.771 0.229
E11.9 Without complications
0.000 0.772 0.228
E00-E07 Disorders of thyroid gland
0.000 0.782 0.218
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.787 0.212
E34.9 Endocrine disorder, unspecified
0.000 0.794 0.206
E34.8 Other specified endocrine disorders
0.000 0.796 0.204
E25.9 Adrenogenital disorder, unspecified
0.000 0.797 0.202
E25.8 Other adrenogenital disorders
0.000 0.797 0.202
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.798 0.202
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.799 0.201
E61.9 Deficiency of nutrient element, unspecified
0.000 0.799 0.201
E61.8 Deficiency of other specified nutrient elements
0.000 0.799 0.201
E61.7 Deficiency of multiple nutrient elements
0.000 0.799 0.201
E61.6 Vanadium deficiency
0.000 0.799 0.201
E61.5 Molybdenum deficiency
0.000 0.799 0.201
E61.4 Chromium deficiency
0.000 0.799 0.201
E61.3 Manganese deficiency
0.000 0.799 0.201
E61.0 Copper deficiency
0.000 0.799 0.201
E53 Deficiency of other B group vitamins
0.000 0.803 0.197
E55.0 Rickets, active
0.000 0.804 0.196
E61.2 Magnesium deficiency
0.000 0.804 0.196
E27 Other disorders of adrenal gland
0.000 0.804 0.196
E30.9 Disorder of puberty, unspecified
0.000 0.805 0.195
E30.8 Other disorders of puberty
0.000 0.805 0.195
E30.1 Precocious puberty
0.000 0.805 0.195
E30.0 Delayed puberty
0.000 0.805 0.195
E32.9 Disease of thymus, unspecified
0.000 0.805 0.195
E32.8 Other diseases of thymus
0.000 0.805 0.195
E32.1 Abscess of thymus
0.000 0.805 0.195
E32.0 Persistent hyperplasia of thymus
0.000 0.805 0.195
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.805 0.195
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.805 0.195
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.805 0.195
E20.8 Other hypoparathyroidism
0.000 0.805 0.195
E20.1 Pseudohypoparathyroidism
0.000 0.805 0.195
E20.0 Idiopathic hypoparathyroidism
0.000 0.805 0.195
E20.9 Hypoparathyroidism, unspecified
0.000 0.805 0.195
E22 Hyperfunction of pituitary gland
0.000 0.806 0.194
E28 Ovarian dysfunction
0.000 0.806 0.193
E34.5 Androgen resistance syndrome
0.000 0.810 0.190
E34.4 Constitutional tall stature
0.000 0.810 0.190
E34.3 Short stature, not elsewhere classified
0.000 0.810 0.190
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.810 0.190
E34.1 Other hypersecretion of intestinal hormones
0.000 0.810 0.190
E05.9 Thyrotoxicosis, unspecified
0.000 0.814 0.186
E26.9 Hyperaldosteronism, unspecified
0.000 0.817 0.183
E26.8 Other hyperaldosteronism
0.000 0.817 0.183
E26.1 Secondary hyperaldosteronism
0.000 0.817 0.183
E31.9 Polyglandular dysfunction, unspecified
0.000 0.822 0.177
E31.8 Other polyglandular dysfunction
0.000 0.822 0.177
E31.1 Polyglandular hyperfunction
0.000 0.822 0.177
K90.9 Intestinal malabsorption, unspecified
0.000 0.825 0.174
E50.9 Vitamin A deficiency, unspecified
0.000 0.827 0.173
E50.8 Other manifestations of vitamin A deficiency
0.000 0.827 0.173
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.827 0.173
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.827 0.173
E50.5 Vitamin A deficiency with night blindness
0.000 0.827 0.173
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.827 0.173
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.827 0.173
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.827 0.173
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.827 0.173
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.827 0.173
E56.9 Vitamin deficiency, unspecified
0.000 0.827 0.173
E56.8 Deficiency of other vitamins
0.000 0.827 0.173
E56.1 Deficiency of vitamin K
0.000 0.827 0.173
E56.0 Deficiency of vitamin E
0.000 0.827 0.173
E63.9 Nutritional deficiency, unspecified
0.000 0.827 0.173
E63.8 Other specified nutritional deficiencies
0.000 0.827 0.173
E63.1 Imbalance of constituents of food intake
0.000 0.827 0.173
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.827 0.173
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.827 0.173
E64.8 Sequelae of other nutritional deficiencies
0.000 0.827 0.173
E64.3 Sequelae of rickets
0.000 0.827 0.173
E64.2 Sequelae of vitamin C deficiency
0.000 0.827 0.173
E64.1 Sequelae of vitamin A deficiency
0.000 0.827 0.173
E64.0 Sequelae of protein-energy malnutrition
0.000 0.827 0.173
E29.9 Testicular dysfunction, unspecified
0.000 0.828 0.172
E29.8 Other testicular dysfunction
0.000 0.828 0.172
E29.0 Testicular hyperfunction
0.000 0.828 0.172
E51.9 Thiamine deficiency, unspecified
0.000 0.828 0.172
E51.8 Other manifestations of thiamine deficiency
0.000 0.828 0.172
E51.1 Beriberi
0.000 0.828 0.172
E51.2 Wernicke's encephalopathy
0.000 0.828 0.172
K50-K52 Noninfective enteritis and colitis
0.168 0.832 0.000
E05.8 Other thyrotoxicosis
0.000 0.833 0.167
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.833 0.166
E45 Retarded development following protein-energy malnutrition
0.000 0.833 0.166
E43 Unspecified severe protein-energy malnutrition
0.000 0.833 0.166
E42 Marasmic kwashiorkor
0.000 0.833 0.166
E41 Nutritional marasmus
0.000 0.833 0.166
E40 Kwashiorkor
0.000 0.833 0.166
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.833 0.167
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.834 0.166
E26.0 Primary hyperaldosteronism
0.000 0.835 0.165
E65-E68 Obesity and other hyperalimentation
0.000 0.835 0.165
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.844 0.156
E00 Congenital iodine-deficiency syndrome
0.000 0.844 0.156
E53.9 Vitamin B deficiency, unspecified
0.000 0.847 0.153
E31.0 Autoimmune polyglandular failure
0.000 0.847 0.152
K50 Crohn's disease [regional enteritis]
0.150 0.850 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.853 0.147
E05.5 Thyroid crisis or storm
0.000 0.855 0.145
E05.4 Thyrotoxicosis factitia
0.000 0.855 0.145
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.855 0.145
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.855 0.145
E27.9 Disorder of adrenal gland, unspecified
0.000 0.855 0.145
E27.8 Other specified disorders of adrenal gland
0.000 0.855 0.145
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.855 0.145
K50.9 Crohn's disease, unspecified
0.143 0.857 0.000
E53.1 Pyridoxine deficiency
0.000 0.859 0.141
E53.0 Riboflavin deficiency
0.000 0.859 0.141
E27.5 Adrenomedullary hyperfunction
0.000 0.859 0.141
E27.0 Other adrenocortical overactivity
0.000 0.859 0.141
E29.1 Testicular hypofunction
0.000 0.860 0.140
E22.0 Acromegaly and pituitary gigantism
0.000 0.860 0.140
E28.3 Primary ovarian failure
0.000 0.860 0.139
E22.8 Other hyperfunction of pituitary gland
0.000 0.860 0.139
E28.9 Ovarian dysfunction, unspecified
0.000 0.861 0.139
E28.8 Other ovarian dysfunction
0.000 0.861 0.139
E28.1 Androgen excess
0.000 0.861 0.139
E28.0 Oestrogen excess
0.000 0.861 0.139
E34.0 Carcinoid syndrome
0.000 0.862 0.137
E06 Thyroiditis
0.000 0.871 0.128
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.873 0.127
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.877 0.123
E22.1 Hyperprolactinaemia
0.000 0.879 0.121
E44.1 Mild protein-energy malnutrition
0.000 0.880 0.119
E44.0 Moderate protein-energy malnutrition
0.000 0.880 0.119
E03 Other hypothyroidism
0.000 0.881 0.119
E67 Other hyperalimentation
0.000 0.881 0.119
E68 Sequelae of hyperalimentation
0.000 0.881 0.119
K50.1 Crohn's disease of large intestine
0.116 0.884 0.000
E07 Other disorders of thyroid
0.000 0.886 0.114
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.888 0.112
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.888 0.112
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.888 0.112
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.888 0.112
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.888 0.112
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.888 0.112
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.888 0.112
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.888 0.112
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.888 0.112
E06.9 Thyroiditis, unspecified
0.000 0.893 0.106
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.896 0.104
E65 Localised adiposity
0.000 0.897 0.102
K50.8 Other Crohn's disease
0.101 0.899 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.899 0.101
E03.8 Other specified hypothyroidism
0.000 0.900 0.100
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.901 0.099
E27.1 Primary adrenocortical insufficiency
0.000 0.904 0.096
E27.2 Addisonian crisis
0.000 0.908 0.092
E06.4 Drug-induced thyroiditis
0.000 0.908 0.092
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.908 0.092
E06.1 Subacute thyroiditis
0.000 0.908 0.092
E06.0 Acute thyroiditis
0.000 0.908 0.092
E83.5 Disorders of calcium metabolism
0.090 0.909 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.911 0.088
E06.5 Other chronic thyroiditis
0.000 0.914 0.086
E03.5 Myxoedema coma
0.000 0.914 0.086
E03.4 Atrophy of thyroid (acquired)
0.000 0.914 0.086
E03.3 Postinfectious hypothyroidism
0.000 0.914 0.086
E03.1 Congenital hypothyroidism without goitre
0.000 0.914 0.086
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.914 0.086
E67.8 Other specified hyperalimentation
0.000 0.915 0.085
E67.3 Hypervitaminosis D
0.000 0.915 0.085
E67.2 Megavitamin-B6 syndrome
0.000 0.915 0.085
E67.1 Hypercarotenaemia
0.000 0.915 0.085
E67.0 Hypervitaminosis A
0.000 0.915 0.085
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.915 0.085
E21.2 Other hyperparathyroidism
0.000 0.916 0.084
E07.1 Dyshormogenetic goitre
0.000 0.918 0.082
E07.0 Hypersecretion of calcitonin
0.000 0.918 0.082
E07.8 Other specified disorders of thyroid
0.000 0.918 0.081
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.926 0.073
E53.8 Deficiency of other specified B group vitamins
0.000 0.929 0.071
K50.0 Crohn's disease of small intestine
0.069 0.931 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.931 0.069
I78.1 Naevus, nonneoplastic
0.062 0.938 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.941 0.059
E04 Other non-toxic goitre
0.000 0.949 0.050
E04.9 Non-toxic goitre, unspecified
0.000 0.955 0.045
E06.3 Autoimmune thyroiditis
0.000 0.960 0.040
E07.9 Disorder of thyroid, unspecified
0.000 0.960 0.040
C18.0 Caecum
0.038 0.962 0.000
E04.8 Other specified non-toxic goitre
0.000 0.963 0.036
L30.9 Dermatitis, unspecified
0.034 0.966 0.000
E66 Obesity
0.000 0.968 0.032
C18.2 Ascending colon
0.030 0.970 0.000
I78 Diseases of capillaries
0.030 0.970 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.971 0.029
C77.2 Intra-abdominal lymph nodes
0.029 0.971 0.000
C18 Malignant neoplasm of colon
0.027 0.973 0.000
C18.5 Splenic flexure
0.026 0.974 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.026 0.974 0.000
I78.8 Other diseases of capillaries
0.025 0.975 0.000
K04.5 Chronic apical periodontitis
0.024 0.976 0.000
I78.9 Disease of capillaries, unspecified
0.023 0.977 0.000
E66.1 Drug-induced obesity
0.000 0.977 0.023
C18.3 Hepatic flexure
0.023 0.977 0.000
C18.8 Overlapping lesion of colon
0.022 0.978 0.000
K90-K93 Other diseases of the digestive system
0.001 0.978 0.021
E21.0 Primary hyperparathyroidism
0.000 0.979 0.021
E04.0 Non-toxic diffuse goitre
0.001 0.980 0.020
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.980 0.020
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.980 0.020
V18.0 Driver injured in nontraffic accident
0.020 0.980 0.000
E66.8 Other obesity
0.000 0.981 0.019
E66.0 Obesity due to excess calories
0.000 0.981 0.018
A08.4 Viral intestinal infection, unspecified
0.000 0.982 0.018
L30 Other dermatitis
0.018 0.982 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.983 0.017
K52 Other non-infective gastro-enteritis and colitis
0.017 0.983 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.016 0.984 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.984 0.015
C18.1 Appendix
0.015 0.984 0.000
C18.4 Transverse colon
0.015 0.985 0.000
E70-E90 Metabolic disorders
0.012 0.986 0.002
L30.1 Dyshidrosis [pompholyx]
0.014 0.986 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.014 0.986 0.000
L30.4 Erythema intertrigo
0.014 0.986 0.000
I83 Varicose veins of lower extremities
0.014 0.986 0.000
H40.2 Primary angle-closure glaucoma
0.013 0.987 0.000
L30.5 Pityriasis alba
0.013 0.987 0.000
L30.2 Cutaneous autosensitisation
0.013 0.987 0.000
L30.0 Nummular dermatitis
0.013 0.987 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.987 0.013
L30.8 Other specified dermatitis
0.013 0.987 0.000
L30.3 Infective dermatitis
0.012 0.987 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.012 0.988 0.000
C18.6 Descending colon
0.012 0.988 0.000
M24.1 Other articular cartilage disorders
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.988 0.011
K93.1 Megacolon in Chagas' disease
0.001 0.988 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.988 0.011
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.011 0.988 0.000
E85 Amyloidosis
0.010 0.989 0.001
I83.0 Varicose veins of lower extremities with ulcer
0.011 0.989 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.989 0.011
C43.5 Malignant melanoma of trunk
0.000 0.989 0.011
E70 Disorders of aromatic amino-acid metabolism
0.009 0.989 0.002
E84 Cystic fibrosis
0.009 0.990 0.002
K52.3 Indeterminate colitis
0.010 0.990 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.009 0.990 0.002
E77 Disorders of glycoprotein metabolism
0.008 0.990 0.002
E76 Disorders of glycosaminoglycan metabolism
0.008 0.990 0.002
E72 Other disorders of amino-acid metabolism
0.008 0.990 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.008 0.990 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.008 0.990 0.002
C43 Malignant melanoma of skin
0.000 0.990 0.010
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.010 0.990 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.009 0.990 0.001
I25.2 Old myocardial infarction
0.000 0.990 0.010
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.990 0.010
E04.1 Non-toxic single thyroid nodule
0.000 0.990 0.010
S62.3 Fracture of other metacarpal bone
0.000 0.990 0.010
E79 Disorders of purine and pyrimidine metabolism
0.008 0.990 0.002
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.990 0.010
E85.9 Amyloidosis, unspecified
0.009 0.990 0.001
E74 Other disorders of carbohydrate metabolism
0.008 0.990 0.002
C43.9 Malignant melanoma of skin, unspecified
0.000 0.991 0.009
E73 Lactose intolerance
0.007 0.991 0.002
E88 Other metabolic disorders
0.008 0.991 0.001
H40.5 Glaucoma secondary to other eye disorders
0.009 0.991 0.000
E85.3 Secondary systemic amyloidosis
0.008 0.991 0.001
C43.4 Malignant melanoma of scalp and neck
0.000 0.991 0.009
K52.1 Toxic gastro-enteritis and colitis
0.009 0.991 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.000 0.991 0.009
M24.18 Other articular cartilage disorders (Other)
0.000 0.991 0.009
M24.14 Other articular cartilage disorders (Hand)
0.000 0.991 0.009
M24.12 Other articular cartilage disorders (Upper arm)
0.000 0.991 0.009
M24.10 Other articular cartilage disorders (Multiple sites)
0.000 0.991 0.009
E80.1 Porphyria cutanea tarda
0.008 0.991 0.000
H40 Glaucoma
0.009 0.991 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.991 0.008
E85.8 Other amyloidosis
0.007 0.992 0.001
E85.2 Heredofamilial amyloidosis, unspecified
0.007 0.992 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.007 0.992 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.007 0.992 0.001
S62.31 Fracture of other metacarpal bone (open)
0.000 0.992 0.008
E70.3 Albinism
0.007 0.992 0.001
E84.9 Cystic fibrosis, unspecified
0.007 0.992 0.001
V18 Pedal cyclist injured in noncollision transport accident
0.008 0.992 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.992 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.992 0.001
E70.2 Disorders of tyrosine metabolism
0.006 0.992 0.001
E70.1 Other hyperphenylalaninaemias
0.006 0.992 0.001
E70.0 Classical phenylketonuria
0.006 0.992 0.001
E84.8 Cystic fibrosis with other manifestations
0.006 0.992 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.006 0.992 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.006 0.992 0.001
I25 Chronic ischaemic heart disease
0.000 0.992 0.008
E75.2 Other sphingolipidosis
0.006 0.992 0.001
E75.6 Lipid storage disorder, unspecified
0.006 0.992 0.001
E75.5 Other lipid storage disorders
0.006 0.992 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.006 0.992 0.001
E75.3 Sphingolipidosis, unspecified
0.006 0.992 0.001
E75.1 Other gangliosidosis
0.006 0.992 0.001
E75.0 GM2 gangliosidosis
0.006 0.992 0.001
E71.3 Disorders of fatty-acid metabolism
0.006 0.992 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.006 0.992 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.006 0.992 0.001
E71.0 Maple-syrup-urine disease
0.006 0.992 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.006 0.992 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.006 0.992 0.001
E72.5 Disorders of glycine metabolism
0.006 0.992 0.001
E72.4 Disorders of ornithine metabolism
0.006 0.992 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.006 0.992 0.001
E72.2 Disorders of urea cycle metabolism
0.006 0.992 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.006 0.992 0.001
E72.0 Disorders of amino-acid transport
0.006 0.992 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.006 0.992 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.006 0.992 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.006 0.992 0.001
E76.2 Other mucopolysaccharidoses
0.006 0.992 0.001
E76.1 Mucopolysaccharidosis, type II
0.006 0.992 0.001
E76.0 Mucopolysaccharidosis, type I
0.006 0.992 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.006 0.992 0.001
E77.8 Other disorders of glycoprotein metabolism
0.006 0.992 0.001
E77.1 Defects in glycoprotein degradation
0.006 0.992 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.006 0.992 0.001
C43.8 Overlapping malignant melanoma of skin
0.000 0.992 0.008
C43.0 Malignant melanoma of lip
0.000 0.992 0.008
E80.2 Other porphyria
0.007 0.992 0.001
E80.7 Disorder of bilirubin metabolism, unspecified
0.007 0.993 0.001
E80.5 Crigler-Najjar syndrome
0.007 0.993 0.001
E80.3 Defects of catalase and peroxydase
0.007 0.993 0.001
E80.0 Hereditary erythropoietic porphyria
0.007 0.993 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.006 0.993 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.006 0.993 0.002
E79.1 Lesch-Nyhan syndrome
0.006 0.993 0.002
H40.0 Glaucoma suspect
0.007 0.993 0.000
E80.6 Other disorders of bilirubin metabolism
0.007 0.993 0.001
C18.7 Sigmoid colon
0.007 0.993 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.006 0.993 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.006 0.993 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.006 0.993 0.001
E74.2 Disorders of galactose metabolism
0.006 0.993 0.001
E74.1 Disorders of fructose metabolism
0.006 0.993 0.001
E74.0 Glycogen storage disease
0.006 0.993 0.001
E85.4 Organ-limited amyloidosis
0.006 0.993 0.001
E88.8 Other specified metabolic disorders
0.006 0.993 0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.005 0.993 0.002
E88.3 Tumour lysis syndrome
0.006 0.993 0.001
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.993 0.007
M24.17 Other articular cartilage disorders (Ankle and foot)
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.005 0.993 0.002
E73.1 Secondary lactase deficiency
0.005 0.993 0.002
E73.0 Congenital lactase deficiency
0.005 0.993 0.002
E88.9 Metabolic disorder, unspecified
0.006 0.993 0.001
H40.4 Glaucoma secondary to eye inflammation
0.007 0.993 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.006 0.993 0.000
H40.8 Other glaucoma
0.007 0.993 0.000
H54.0 Blindness, both eyes
0.000 0.993 0.007
L03.1 Cellulitis of other parts of limb
0.007 0.993 0.000
H40.3 Glaucoma secondary to eye trauma
0.006 0.993 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.006 0.994 0.000
H40.6 Glaucoma secondary to drugs
0.006 0.994 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.000 0.994 0.006
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.006 0.994 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.005 0.994 0.001
V18.1 Passenger injured in nontraffic accident
0.006 0.994 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.005 0.994 0.001
E80.4 Gilbert's syndrome
0.006 0.994 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.994 0.006
V18.5 Passenger injured in traffic accident
0.006 0.994 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.006 0.994 0.000
V18.4 Driver injured in traffic accident
0.006 0.994 0.000
H54.7 Unspecified visual loss
0.000 0.994 0.006
I25.6 Silent myocardial ischaemia
0.000 0.994 0.006
Z50.8 Care involving use of rehabilitation procedures
0.000 0.994 0.006
H54 Blindness and low vision
0.000 0.994 0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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