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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117426
log Bayes Factor = 98.2997
Chromosome 6   position 29,272,012  (GRCh37) Explore rs3117426 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
E10.3 With ophthalmic complications
0.992 0.008 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.991 0.009 0.000
N40 Hyperplasia of prostate
0.000 0.016 0.984
E10.2 With renal complications
0.973 0.027 0.000
E10.1 With ketoacidosis
0.927 0.073 0.000
E10.4 With neurological complications
0.916 0.084 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.097 0.903
E16.0 Drug-induced hypoglycaemia without coma
0.896 0.104 0.000
E16.1 Other hypoglycaemia
0.859 0.141 0.000
E40-E46 Malnutrition
0.850 0.150 0.000
N40-N51 Diseases of male genital organs
0.000 0.156 0.844
E11 Non-insulin-dependent diabetes mellitus
0.841 0.159 0.000
N42 Other disorders of prostate
0.000 0.171 0.829
E14 Unspecified diabetes mellitus
0.822 0.178 0.000
E11.5 With peripheral circulatory complications
0.819 0.181 0.000
N41 Inflammatory diseases of prostate
0.000 0.184 0.816
E13 Other specified diabetes mellitus
0.804 0.196 0.000
N42.8 Other specified disorders of prostate
0.000 0.197 0.803
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.202 0.798
E10.6 With other specified complications
0.792 0.208 0.000
E10.7 With multiple complications
0.792 0.208 0.000
E10.5 With peripheral circulatory complications
0.784 0.216 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.217 0.783
E10.0 With coma
0.782 0.218 0.000
E46 Unspecified protein-energy malnutrition
0.743 0.257 0.000
K90 Intestinal malabsorption
0.737 0.263 0.000
E14.3 With ophthalmic complications
0.736 0.264 0.000
E03 Other hypothyroidism
0.731 0.269 0.000
E11.3 With ophthalmic complications
0.731 0.269 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
E07 Other disorders of thyroid
0.716 0.284 0.000
N41.0 Acute prostatitis
0.000 0.317 0.683
E05.8 Other thyrotoxicosis
0.667 0.333 0.000
E14.1 With ketoacidosis
0.657 0.343 0.000
N44 Torsion of testis
0.000 0.347 0.653
E14.8 With unspecified complications
0.648 0.352 0.000
E50-E64 Other nutritional deficiencies
0.644 0.356 0.000
E13.9 Without complications
0.640 0.360 0.000
E10.8 With unspecified complications
0.630 0.370 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.628 0.372 0.000
N42.2 Atrophy of prostate
0.000 0.373 0.627
N42.0 Calculus of prostate
0.000 0.374 0.626
E06 Thyroiditis
0.624 0.376 0.000
K40 Inguinal hernia
0.001 0.379 0.620
N46 Male infertility
0.000 0.379 0.621
E14.4 With neurological complications
0.618 0.382 0.000
E11.0 With coma
0.612 0.388 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.610 0.390 0.000
E45 Retarded development following protein-energy malnutrition
0.610 0.390 0.000
E43 Unspecified severe protein-energy malnutrition
0.610 0.390 0.000
E42 Marasmic kwashiorkor
0.610 0.390 0.000
E41 Nutritional marasmus
0.610 0.390 0.000
E40 Kwashiorkor
0.610 0.390 0.000
E13.3 With ophthalmic complications
0.608 0.392 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.395 0.605
E11.7 With multiple complications
0.603 0.397 0.000
E14.2 Withrenal complications
0.600 0.400 0.000
E11.1 With ketoacidosis
0.598 0.402 0.000
N42.3 Dysplasia of prostate
0.000 0.405 0.595
E07.8 Other specified disorders of thyroid
0.594 0.406 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.408 0.592
E14.6 With other specified complications
0.590 0.410 0.000
E14.7 With multiple complications
0.589 0.410 0.000
E14.0 With coma
0.589 0.410 0.000
N41.3 Prostatocystitis
0.000 0.415 0.585
N41.2 Abscess of prostate
0.000 0.415 0.585
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.580 0.420 0.000
E13.8 With unspecified complications
0.576 0.424 0.000
E13.7 With multiple complications
0.576 0.424 0.000
E13.6 With other specified complications
0.576 0.424 0.000
E13.5 With peripheral circulatory complications
0.576 0.424 0.000
E13.4 With neurological complications
0.576 0.424 0.000
E13.2 With renal complications
0.576 0.424 0.000
E13.1 With ketoacidosis
0.576 0.424 0.000
E13.0 With coma
0.576 0.424 0.000
E11.6 With other specified complications
0.574 0.426 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.433 0.567
K90.9 Intestinal malabsorption, unspecified
0.563 0.437 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.556 0.444 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.446 0.554
E14.5 With peripheral circulatory complications
0.553 0.447 0.000
K90.8 Other intestinal malabsorption
0.552 0.448 0.000
E03.8 Other specified hypothyroidism
0.544 0.456 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.541 0.459 0.000
H04 Disorders of lachrymal system
0.529 0.471 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.529 0.471 0.000
K90.3 Pancreatic steatorrhoea
0.528 0.472 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.528 0.472 0.000
K90.1 Tropical sprue
0.528 0.472 0.000
K75.4 Autoimmune hepatitis
0.527 0.473 0.000
E03.5 Myxoedema coma
0.524 0.476 0.000
E03.4 Atrophy of thyroid (acquired)
0.524 0.476 0.000
E03.3 Postinfectious hypothyroidism
0.524 0.476 0.000
E03.1 Congenital hypothyroidism without goitre
0.522 0.478 0.000
K75 Other inflammatory liver diseases
0.521 0.479 0.000
N45 Orchitis and epididymitis
0.000 0.481 0.518
H02 Other disorders of eyelid
0.516 0.484 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.516 0.484 0.000
E11.2 With renal complications
0.515 0.485 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E07.1 Dyshormogenetic goitre
0.513 0.487 0.000
E07.0 Hypersecretion of calcitonin
0.513 0.487 0.000
H04.1 Other disorders of lachrymal gland
0.505 0.495 0.000
H02.1 Ectropion of eyelid
0.504 0.496 0.000
E61 Deficiency of other nutrient elements
0.503 0.497 0.000
E06.9 Thyroiditis, unspecified
0.498 0.502 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.507 0.493
E11.8 With unspecified complications
0.492 0.508 0.000
K70-K77 Diseases of liver
0.489 0.511 0.000
H02.5 Other disorders affecting eyelid function
0.485 0.515 0.000
H02.3 Blepharochalasis
0.485 0.515 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.485 0.515 0.000
H05 Disorders of orbit
0.477 0.523 0.000
K75.8 Other specified inflammatory liver diseases
0.474 0.526 0.000
H01 Other inflammation of eyelid
0.473 0.527 0.000
K72 Hepatic failure, not elsewhere classified
0.471 0.529 0.000
H04.8 Other disorders of lachrymal system
0.467 0.533 0.000
K75.9 Inflammatory liver disease, unspecified
0.467 0.533 0.000
H04.4 Chronic inflammation of lachrymal passages
0.465 0.535 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.462 0.538 0.000
E63 Other nutritional deficiencies
0.462 0.538 0.000
E50 Vitamin A deficiency
0.462 0.538 0.000
E60 Dietary zinc deficiency
0.462 0.538 0.000
E59 Dietary selenium deficiency
0.462 0.538 0.000
E58 Dietary calcium deficiency
0.462 0.538 0.000
E54 Ascorbic acid deficiency
0.462 0.538 0.000
E52 Niacin deficiency [pellagra]
0.462 0.538 0.000
E56 Other vitamin deficiencies
0.460 0.540 0.000
E51 Thiamine deficiency
0.460 0.540 0.000
E03.9 Hypothyroidism, unspecified
0.459 0.541 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.001 0.545 0.455
E06.5 Other chronic thyroiditis
0.448 0.552 0.000
E06.4 Drug-induced thyroiditis
0.448 0.552 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.448 0.552 0.000
E06.1 Subacute thyroiditis
0.448 0.552 0.000
E06.0 Acute thyroiditis
0.448 0.552 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.001 0.555 0.445
K40.1 Bilateral inguinal hernia, with gangrene
0.001 0.555 0.445
K72.9 Hepatic failure, unspecified
0.439 0.561 0.000
E44.1 Mild protein-energy malnutrition
0.437 0.563 0.000
E44.0 Moderate protein-energy malnutrition
0.437 0.563 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.566 0.434
N51.2 Balanitis in diseases classified elsewhere
0.000 0.566 0.434
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.566 0.434
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.566 0.434
N50 Other disorders of male genital organs
0.000 0.568 0.431
N41.1 Chronic prostatitis
0.000 0.577 0.423
K73 Chronic hepatitis, not elsewhere classified
0.423 0.577 0.000
E61.1 Iron deficiency
0.422 0.578 0.000
H05.0 Acute inflammation of orbit
0.421 0.579 0.000
H02.0 Entropion and trichiasis of eyelid
0.420 0.580 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.417 0.583 0.000
K70 Alcoholic liver disease
0.413 0.587 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.412 0.587 0.000
E55 Vitamin D deficiency
0.412 0.588 0.000
H01.9 Inflammation of eyelid, unspecified
0.408 0.592 0.000
K72.0 Acute and subacute hepatic failure
0.407 0.593 0.000
H01.0 Blepharitis
0.406 0.594 0.000
E65-E68 Obesity and other hyperalimentation
0.406 0.594 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.603 0.397
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.603 0.397
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.603 0.397
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.603 0.397
H02.6 Xanthelasma of eyelid
0.397 0.603 0.000
K90-K93 Other diseases of the digestive system
0.395 0.605 0.001
H04.6 Other changes in lachrymal passages
0.393 0.607 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.610 0.390
E53 Deficiency of other B group vitamins
0.389 0.611 0.000
Chapter VII Diseases of the eye and adnexa
0.387 0.613 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.386 0.614 0.000
K71 Toxic liver disease
0.383 0.617 0.000
H05.9 Disorder of orbit, unspecified
0.380 0.620 0.000
H02.2 Lagophthalmos
0.380 0.620 0.000
H04.0 Dacryoadenitis
0.379 0.621 0.000
H05.2 Exophthalmic conditions
0.379 0.621 0.000
N50.9 Disorder of male genital organs, unspecified
0.000 0.622 0.378
E07.9 Disorder of thyroid, unspecified
0.375 0.624 0.000
K75.2 Nonspecific reactive hepatitis
0.374 0.626 0.000
K75.1 Phlebitis of portal vein
0.374 0.626 0.000
Chapter XI Diseases of the digestive system
0.373 0.627 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.370 0.630 0.000
# Top node
0.369 0.631 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.367 0.633 0.000
M05-M14 Inflammatory polyarthropathies
0.361 0.639 0.000
E11.9 Without complications
0.361 0.639 0.000
E61.9 Deficiency of nutrient element, unspecified
0.361 0.639 0.000
E61.8 Deficiency of other specified nutrient elements
0.361 0.639 0.000
E61.7 Deficiency of multiple nutrient elements
0.361 0.639 0.000
E61.6 Vanadium deficiency
0.361 0.639 0.000
E61.5 Molybdenum deficiency
0.361 0.639 0.000
E61.4 Chromium deficiency
0.361 0.639 0.000
E61.3 Manganese deficiency
0.361 0.639 0.000
E61.0 Copper deficiency
0.361 0.639 0.000
K70.1 Alcoholic hepatitis
0.358 0.642 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.355 0.645 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.645 0.354
M67.8 Other specified disorders of synovium and tendon
0.352 0.648 0.000
K75.0 Abscess of liver
0.352 0.648 0.000
K77 Liver disorders in diseases classified elsewhere
0.351 0.649 0.000
M65-M68 Disorders of synovium and tendon
0.350 0.650 0.000
M67 Other disorders of synovium and tendon
0.350 0.650 0.000
K72.1 Chronic hepatic failure
0.350 0.650 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.348 0.652 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.344 0.656 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.344 0.656 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.342 0.658 0.000
H05.3 Deformity of orbit
0.342 0.658 0.000
H05.1 Chronic inflammatory disorders of orbit
0.342 0.658 0.000
M86-M90 Other osteopathies
0.342 0.658 0.000
H01.1 Non-infectious dermatoses of eyelid
0.339 0.660 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.339 0.661 0.000
K73.9 Chronic hepatitis, unspecified
0.338 0.661 0.000
M86 Osteomyelitis
0.337 0.663 0.000
K70.4 Alcoholic hepatic failure
0.336 0.664 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.336 0.664 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.335 0.665 0.000
M60-M63 Disorders of muscles
0.333 0.667 0.000
H05.8 Other disorders of orbit
0.332 0.668 0.000
E50.9 Vitamin A deficiency, unspecified
0.331 0.669 0.000
E50.8 Other manifestations of vitamin A deficiency
0.331 0.669 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.331 0.669 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.331 0.669 0.000
E50.5 Vitamin A deficiency with night blindness
0.331 0.669 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.331 0.669 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.331 0.669 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.331 0.669 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.331 0.669 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.331 0.669 0.000
E63.9 Nutritional deficiency, unspecified
0.331 0.669 0.000
E63.8 Other specified nutritional deficiencies
0.331 0.669 0.000
E63.1 Imbalance of constituents of food intake
0.331 0.669 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.331 0.669 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.331 0.669 0.000
E64.8 Sequelae of other nutritional deficiencies
0.331 0.669 0.000
E64.3 Sequelae of rickets
0.331 0.669 0.000
E64.2 Sequelae of vitamin C deficiency
0.331 0.669 0.000
E64.1 Sequelae of vitamin A deficiency
0.331 0.669 0.000
E64.0 Sequelae of protein-energy malnutrition
0.331 0.669 0.000
E56.9 Vitamin deficiency, unspecified
0.330 0.670 0.000
E56.8 Deficiency of other vitamins
0.330 0.670 0.000
E56.0 Deficiency of vitamin E
0.330 0.670 0.000
M06 Other rheumatoid arthritis
0.330 0.670 0.000
E51.9 Thiamine deficiency, unspecified
0.330 0.670 0.000
E51.8 Other manifestations of thiamine deficiency
0.330 0.670 0.000
E51.1 Beriberi
0.330 0.670 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.329 0.671 0.000
E56.1 Deficiency of vitamin K
0.329 0.671 0.000
E51.2 Wernicke's encephalopathy
0.328 0.672 0.000
M86.9 Osteomyelitis, unspecified
0.328 0.672 0.000
H43-H45 Disorders of vitreous body and globe
0.327 0.673 0.000
E61.2 Magnesium deficiency
0.326 0.674 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.322 0.678 0.000
H05.4 Enophthalmos
0.320 0.680 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.318 0.682 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.316 0.684 0.000
M10 Gout
0.315 0.685 0.000
N43 Hydrocele and spermatocele
0.000 0.685 0.315
H49 Paralytic strabismus
0.315 0.685 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.314 0.686 0.000
M62 Other disorders of muscle
0.312 0.688 0.000
H01.8 Other specified inflammation of eyelid
0.312 0.688 0.000
H30-H36 Disorders of choroid and retina
0.311 0.689 0.000
N50.0 Atrophy of testis
0.000 0.690 0.310
Q43 Other congenital malformations of intestine
0.309 0.691 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.307 0.693 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.307 0.693 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.303 0.697 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.303 0.697 0.000
M06.9 Rheumatoid arthritis, unspecified
0.303 0.697 0.000
M11 Other crystal arthropathies
0.303 0.697 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.302 0.698 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.302 0.698 0.000
M13 Other arthritis
0.301 0.699 0.000
K70.0 Alcoholic fatty liver
0.301 0.699 0.000
D60-D64 Aplastic and other anaemias
0.300 0.700 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.299 0.701 0.000
H36 Retinal disorders in diseases classified elsewhere
0.299 0.701 0.000
N48 Other disorders of penis
0.000 0.701 0.299
H16 Keratitis
0.298 0.702 0.000
H50 Other strabismus
0.296 0.704 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.296 0.704 0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.296 0.704 0.000
E55.0 Rickets, active
0.295 0.705 0.000
D64 Other anaemias
0.295 0.705 0.000
D64.9 Anaemia, unspecified
0.294 0.706 0.000
K70.9 Alcoholic liver disease, unspecified
0.294 0.706 0.000
M10.0 Idiopathic gout
0.292 0.708 0.000
M12 Other specific arthropathies
0.292 0.708 0.000
Q45 Other congenital malformations of digestive system
0.292 0.708 0.000
E67 Other hyperalimentation
0.291 0.709 0.000
E68 Sequelae of hyperalimentation
0.291 0.709 0.000
H36.0 Diabetic retinopathy
0.290 0.710 0.000
M62.8 Other specified disorders of muscle
0.290 0.710 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.289 0.711 0.000
M13.0 Polyarthritis, unspecified
0.288 0.712 0.000
M86.6 Other chronic osteomyelitis
0.286 0.714 0.000
M91-M94 Chondropathies
0.285 0.715 0.000
D80-D89 Certain disorders involving the immune mechanism
0.285 0.715 0.000
M20-M25 Other joint disorders
0.285 0.715 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.285 0.715 0.000
H49.1 Fourth [trochlear] nerve palsy
0.284 0.716 0.000
K71.0 Toxic liver disease with cholestasis
0.284 0.716 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.283 0.716 0.001
H04.2 Epiphora
0.283 0.717 0.000
H06.2 Dysthyroid exophthalmos
0.283 0.717 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.281 0.719 0.000
M89 Other disorders of bone
0.281 0.719 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.281 0.719 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.280 0.720 0.000
E53.1 Pyridoxine deficiency
0.279 0.721 0.000
E53.0 Riboflavin deficiency
0.279 0.721 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.279 0.721 0.000
M06.4 Inflammatory polyarthropathy
0.278 0.722 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.277 0.723 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.277 0.723 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.277 0.723 0.000
H04.9 Disorder of lachrymal system, unspecified
0.275 0.725 0.000
Q76 Congenital malformations of spine and bony thorax
0.275 0.725 0.000
M31 Other necrotising vasculopathies
0.275 0.725 0.000
K71.9 Toxic liver disease, unspecified
0.275 0.725 0.000
K71.8 Toxic liver disease with other disorders of liver
0.275 0.725 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.275 0.725 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.275 0.725 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.275 0.725 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.275 0.725 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.275 0.725 0.000
K71.2 Toxic liver disease with acute hepatitis
0.275 0.725 0.000
K35-K38 Diseases of appendix
0.274 0.726 0.000
Q43.8 Other specified congenital malformations of intestine
0.274 0.726 0.000
H50.9 Strabismus, unspecified
0.273 0.727 0.000
H43 Disorders of vitreous body
0.273 0.727 0.000
H16.0 Corneal ulcer
0.271 0.729 0.000
H50.0 Convergent concomitant strabismus
0.267 0.733 0.000
N48.1 Balanoposthitis
0.000 0.734 0.266
Q65 Congenital deformities of hip
0.266 0.734 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.265 0.735 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.265 0.735 0.000
M14 Arthropathies in other diseases classified elsewhere
0.265 0.735 0.000
H34 Retinal vascular occlusions
0.265 0.735 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.264 0.735 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.264 0.736 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.264 0.736 0.000
Q39 Congenital malformations of oesophagus
0.262 0.738 0.000
M31.6 Other giant cell arteritis
0.262 0.738 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.259 0.741 0.000
M08 Juvenile arthritis
0.259 0.741 0.000
M86.8 Other osteomyelitis
0.259 0.741 0.000
M67.0 Short Achilles tendon (acquired)
0.258 0.742 0.000
S20-S29 Injuries to the thorax
0.258 0.742 0.000
M34 Systemic sclerosis
0.258 0.742 0.000
Q74 Other congenital malformations of limb(s)
0.257 0.743 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.257 0.743 0.000
E11.4 With neurological complications
0.256 0.744 0.000
K70.3 Alcoholic cirrhosis of liver
0.255 0.745 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.255 0.745 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.254 0.746 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.254 0.746 0.000
H44 Disorders of globe
0.252 0.748 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.252 0.748 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.252 0.748 0.000
M35 Other systemic involvement of connective tissue
0.252 0.748 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.252 0.748 0.000
H16.8 Other keratitis
0.251 0.748 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.251 0.749 0.000
M00-M03 Infectious arthropathies
0.251 0.749 0.000
M07 Psoriatic and enteropathic arthropathies
0.251 0.749 0.000
K35 Acute appendicitis
0.251 0.749 0.000
M89.5 Osteolysis
0.251 0.749 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.251 0.749 0.000
M67.3 Transient synovitis
0.251 0.749 0.000
M06.8 Other specified rheumatoid arthritis
0.251 0.749 0.000
Q68 Other congenital musculoskeletal deformities
0.250 0.750 0.000
Q35-Q37 Cleft lip and cleft palate
0.250 0.750 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.250 0.750 0.000
Q24 Other congenital malformations of heart
0.250 0.750 0.000
H49.2 Sixth [abducent] nerve palsy
0.250 0.750 0.000
E06.3 Autoimmune thyroiditis
0.249 0.751 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.249 0.751 0.000
Z46.6 Fitting and adjustment of urinary device
0.000 0.752 0.248
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.248 0.752 0.000
S20 Superficial injury of thorax
0.248 0.752 0.000
E53.9 Vitamin B deficiency, unspecified
0.248 0.752 0.000
Q43.3 Congenital malformations of intestinal fixation
0.248 0.752 0.000
Q28 Other congenital malformations of circulatory system
0.247 0.752 0.000
D61 Other aplastic anaemias
0.247 0.753 0.000
H18 Other disorders of cornea
0.247 0.753 0.000
H51 Other disorders of binocular movement
0.246 0.753 0.000
Q44.6 Cystic disease of liver
0.246 0.754 0.000
E53.8 Deficiency of other specified B group vitamins
0.246 0.754 0.000
Q45.8 Other specified congenital malformations of digestive system
0.246 0.754 0.000
M62.6 Muscle strain
0.246 0.754 0.000
H17 Corneal scars and opacities
0.246 0.754 0.000
E55.9 Vitamin D deficiency, unspecified
0.245 0.754 0.000
D80 Immunodeficiency with predominantly antibody defects
0.245 0.754 0.000
H49.0 Third [oculomotor] nerve palsy
0.245 0.755 0.000
M11.9 Crystal arthropathy, unspecified
0.245 0.755 0.000
M10.00 Idiopathic gout (Multiple sites)
0.245 0.755 0.000
H43.9 Disorder of vitreous body, unspecified
0.245 0.755 0.000
Q40 Other congenital malformations of upper alimentary tract
0.243 0.757 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.243 0.757 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.243 0.757 0.000
M99 Biomechanical lesions, not elsewhere classified
0.242 0.758 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.242 0.758 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.242 0.758 0.000
M86.3 Chronic multifocal osteomyelitis
0.242 0.758 0.000
M86.2 Subacute osteomyelitis
0.242 0.758 0.000
M86.1 Other acute osteomyelitis
0.242 0.758 0.000
M86.0 Acute haematogenous osteomyelitis
0.242 0.758 0.000
M35.0 Sicca syndrome [Sjogren]
0.242 0.758 0.000
E20-E35 Disorders of other endocrine glands
0.242 0.758 0.000
H49.8 Other paralytic strabismus
0.241 0.759 0.000
M67.4 Ganglion
0.241 0.759 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.241 0.759 0.000
M96.5 Postradiation scoliosis
0.241 0.759 0.000
M96.4 Postsurgical lordosis
0.241 0.759 0.000
M96.3 Postlaminectomy kyphosis
0.241 0.759 0.000
M96.2 Postradiation kyphosis
0.241 0.759 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.241 0.759 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.241 0.759 0.000
Q43.1 Hirschsprung's disease
0.241 0.759 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.241 0.759 0.000
Q00-Q07 Congenital malformations of the nervous system
0.240 0.760 0.000
M94 Other disorders of cartilage
0.240 0.760 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.240 0.760 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.239 0.761 0.000
M61 Calcification and ossification of muscle
0.239 0.761 0.000
M23 Internal derangement of knee
0.239 0.761 0.000
M13.8 Other specified arthritis
0.238 0.762 0.000
H16.4 Corneal neovascularisation
0.237 0.763 0.000
M06.2 Rheumatoid bursitis
0.237 0.763 0.000
M06.1 Adult-onset Still's disease
0.237 0.763 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.001 0.764 0.236
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.236 0.764 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.236 0.764 0.000
Chapter XX External causes of morbidity and mortality
0.236 0.764 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.235 0.765 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.235 0.765 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.235 0.765 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.235 0.765 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.235 0.765 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.234 0.766 0.000
H50.8 Other specified strabismus
0.234 0.766 0.000
M06.0 Seronegative rheumatoid arthritis
0.233 0.767 0.000
M11.8 Other specified crystal arthropathies
0.233 0.767 0.000
N50.1 Vascular disorders of male genital organs
0.000 0.767 0.233
Q45.3 Other congenital malformations of pancreas and pancreatic duct
0.232 0.768 0.000
H31 Other disorders of choroid
0.232 0.768 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.232 0.768 0.000
K35.9 Acute appendicitis, unspecified
0.230 0.770 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.230 0.770 0.000
S40-S49 Injuries to the shoulder and upper arm
0.230 0.770 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.229 0.770 0.000
D83 Common variable immunodeficiency
0.229 0.771 0.000
Q65.8 Other congenital deformities of hip
0.229 0.771 0.000
H30 Chorioretinal inflammation
0.229 0.771 0.000
M60 Myositis
0.228 0.771 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.228 0.771 0.000
S21 Open wound of thorax
0.228 0.772 0.000
D84 Other immunodeficiencies
0.228 0.772 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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